LOCUS       DAVKAU010000001       124013 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVKAU010000001 DAVKAU010000000
VERSION     DAVKAU010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 124013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 124013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..124013
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.001"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..110
                     /locus_tag="VWX48_000001"
     CDS             <1..110
                     /locus_tag="VWX48_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9170738.1"
                     /translation="EEVMNQLQDVIQGLEKEVIKSIVNRRWTRMLFESR"
     gene            complement(227..574)
                     /locus_tag="VWX48_000002"
     CDS             complement(227..574)
                     /locus_tag="VWX48_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9170739.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(685..2460)
                     /gene="spxB"
                     /locus_tag="VWX48_000003"
     CDS             complement(685..2460)
                     /gene="spxB"
                     /locus_tag="VWX48_000003"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU9170740.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2667..4910)
                     /locus_tag="VWX48_000004"
     CDS             complement(2667..4910)
                     /locus_tag="VWX48_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9170741.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEAIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4920..5291)
                     /locus_tag="VWX48_000005"
     CDS             complement(4920..5291)
                     /locus_tag="VWX48_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU9170742.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            complement(5302..5697)
                     /locus_tag="VWX48_000006"
     CDS             complement(5302..5697)
                     /locus_tag="VWX48_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU9170743.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5881..5979
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6063..6854
                     /gene="thiD"
                     /locus_tag="VWX48_000007"
     CDS             6063..6854
                     /gene="thiD"
                     /locus_tag="VWX48_000007"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9170744.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7063..7695)
                     /locus_tag="VWX48_000008"
     CDS             complement(7063..7695)
                     /locus_tag="VWX48_000008"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9170745.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7688..8491)
                     /locus_tag="VWX48_000009"
     CDS             complement(7688..8491)
                     /locus_tag="VWX48_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9170746.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8491..9015)
                     /gene="thiW"
                     /locus_tag="VWX48_000010"
     CDS             complement(8491..9015)
                     /gene="thiW"
                     /locus_tag="VWX48_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU9170747.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9020..9712)
                     /gene="tenA"
                     /locus_tag="VWX48_000011"
     CDS             complement(9020..9712)
                     /gene="tenA"
                     /locus_tag="VWX48_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU9170748.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9723..10373)
                     /locus_tag="VWX48_000012"
     CDS             complement(9723..10373)
                     /locus_tag="VWX48_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU9170749.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQFKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10375..11760)
                     /locus_tag="VWX48_000013"
     CDS             complement(10375..11760)
                     /locus_tag="VWX48_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170750.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHVQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIARKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTSIVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11761..12321)
                     /locus_tag="VWX48_000014"
     CDS             complement(11761..12321)
                     /locus_tag="VWX48_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9170751.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSAMIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLSFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12583..12671)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12880..13509)
                     /locus_tag="VWX48_000015"
     CDS             complement(12880..13509)
                     /locus_tag="VWX48_000015"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9170752.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13511..14293)
                     /gene="thiM"
                     /locus_tag="VWX48_000016"
     CDS             complement(13511..14293)
                     /gene="thiM"
                     /locus_tag="VWX48_000016"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9170753.1"
                     /translation="MTSLKLLKEKVPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            14384..14470
                     /locus_tag="VWX48_000017"
                     /pseudo
     CDS             14384..14470
                     /locus_tag="VWX48_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(14575..15243)
                     /locus_tag="VWX48_000018"
     CDS             complement(14575..15243)
                     /locus_tag="VWX48_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU9170754.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDFALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15458..15546)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15800..16936)
                     /gene="lctO"
                     /locus_tag="VWX48_000019"
     CDS             complement(15800..16936)
                     /gene="lctO"
                     /locus_tag="VWX48_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU9170755.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17561..19051)
                     /gene="lysS"
                     /locus_tag="VWX48_000020"
     CDS             complement(17561..19051)
                     /gene="lysS"
                     /locus_tag="VWX48_000020"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU9170756.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19178..19324)
                     /locus_tag="VWX48_000021"
     CDS             complement(19178..19324)
                     /locus_tag="VWX48_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU9170757.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            19539..20219
                     /locus_tag="VWX48_000022"
     CDS             19539..20219
                     /locus_tag="VWX48_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9170758.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIHLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
     gene            20179..20856
                     /locus_tag="VWX48_000023"
     CDS             20179..20856
                     /locus_tag="VWX48_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9170759.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            20857..21614
                     /locus_tag="VWX48_000024"
                     /pseudo
     CDS             20857..21614
                     /locus_tag="VWX48_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21626..22492
                     /locus_tag="VWX48_000025"
     CDS             21626..22492
                     /locus_tag="VWX48_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9170760.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGPSSGKTTAKARTID
                     ENKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(22579..23226)
                     /locus_tag="VWX48_000026"
     CDS             complement(22579..23226)
                     /locus_tag="VWX48_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170761.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23223..23921)
                     /locus_tag="VWX48_000027"
     CDS             complement(23223..23921)
                     /locus_tag="VWX48_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170762.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAIVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(23931..24683)
                     /locus_tag="VWX48_000028"
     CDS             complement(23931..24683)
                     /locus_tag="VWX48_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170763.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24683..25447)
                     /locus_tag="VWX48_000029"
     CDS             complement(24683..25447)
                     /locus_tag="VWX48_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170764.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(26126..26758)
                     /locus_tag="VWX48_000030"
     CDS             complement(26126..26758)
                     /locus_tag="VWX48_000030"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU9170765.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26792..27493)
                     /gene="pyrF"
                     /locus_tag="VWX48_000031"
     CDS             complement(26792..27493)
                     /gene="pyrF"
                     /locus_tag="VWX48_000031"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU9170766.1"
                     /translation="MREHRPIIALDFPNFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(27726..28925)
                     /gene="divIB"
                     /locus_tag="VWX48_000032"
     CDS             complement(27726..28925)
                     /gene="divIB"
                     /locus_tag="VWX48_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU9170767.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            complement(28935..29993)
                     /locus_tag="VWX48_000033"
     CDS             complement(28935..29993)
                     /locus_tag="VWX48_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU9170768.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(29995..31335)
                     /locus_tag="VWX48_000034"
     CDS             complement(29995..31335)
                     /locus_tag="VWX48_000034"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU9170769.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNV
                     ENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQ
                     KALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAY
                     VEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE"
     gene            complement(31439..32080)
                     /locus_tag="VWX48_000035"
     CDS             complement(31439..32080)
                     /locus_tag="VWX48_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170770.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32082..34103)
                     /locus_tag="VWX48_000036"
     CDS             complement(32082..34103)
                     /locus_tag="VWX48_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9170771.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMALTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLIDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(34174..34473)
                     /locus_tag="VWX48_000037"
     CDS             complement(34174..34473)
                     /locus_tag="VWX48_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9170772.1"
                     /translation="MKTKKHRLLALVLISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(34838..35092)
                     /locus_tag="VWX48_000038"
     CDS             complement(34838..35092)
                     /locus_tag="VWX48_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU9170773.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35112..36953)
                     /gene="typA"
                     /locus_tag="VWX48_000039"
     CDS             complement(35112..36953)
                     /gene="typA"
                     /locus_tag="VWX48_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU9170774.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37115..37840
                     /locus_tag="VWX48_000040"
     CDS             37115..37840
                     /locus_tag="VWX48_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEU9170775.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            complement(37880..38107)
                     /locus_tag="VWX48_000041"
     CDS             complement(37880..38107)
                     /locus_tag="VWX48_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170776.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38196..38576)
                     /locus_tag="VWX48_000042"
     CDS             complement(38196..38576)
                     /locus_tag="VWX48_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9170777.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(38576..38845)
                     /locus_tag="VWX48_000043"
     CDS             complement(38576..38845)
                     /locus_tag="VWX48_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU9170778.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            38909..39817
                     /locus_tag="VWX48_000044"
     CDS             38909..39817
                     /locus_tag="VWX48_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9170779.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(39871..40626)
                     /locus_tag="VWX48_000045"
     CDS             complement(39871..40626)
                     /locus_tag="VWX48_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9170780.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40647..41576)
                     /locus_tag="VWX48_000046"
     CDS             complement(40647..41576)
                     /locus_tag="VWX48_000046"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU9170781.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(41591..42214)
                     /locus_tag="VWX48_000047"
     CDS             complement(41591..42214)
                     /locus_tag="VWX48_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU9170782.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42207..43445)
                     /gene="hflX"
                     /locus_tag="VWX48_000048"
     CDS             complement(42207..43445)
                     /gene="hflX"
                     /locus_tag="VWX48_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU9170783.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(43438..44322)
                     /gene="miaA"
                     /locus_tag="VWX48_000049"
     CDS             complement(43438..44322)
                     /gene="miaA"
                     /locus_tag="VWX48_000049"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU9170784.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIKEFLDD"
     gene            44443..44613
                     /locus_tag="VWX48_000050"
     CDS             44443..44613
                     /locus_tag="VWX48_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU9170785.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(44661..45500)
                     /locus_tag="VWX48_000051"
     CDS             complement(44661..45500)
                     /locus_tag="VWX48_000051"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU9170786.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(45597..46556)
                     /locus_tag="VWX48_000052"
     CDS             complement(45597..46556)
                     /locus_tag="VWX48_000052"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU9170787.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(46691..47681)
                     /locus_tag="VWX48_000053"
                     /pseudo
     CDS             complement(46691..47681)
                     /locus_tag="VWX48_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(47731..48348)
                     /locus_tag="VWX48_000054"
     CDS             complement(47731..48348)
                     /locus_tag="VWX48_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9170788.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGATLTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(48349..50070)
                     /gene="pabB"
                     /locus_tag="VWX48_000055"
     CDS             complement(48349..50070)
                     /gene="pabB"
                     /locus_tag="VWX48_000055"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU9170789.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVAEVADLLAQVESYQ
                     EQDYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAENYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLGQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50139..55574)
                     /locus_tag="VWX48_000056"
     CDS             complement(50139..55574)
                     /locus_tag="VWX48_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9170790.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPSPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETVNQPVEQPKVETPAVEKQTEPTEEPKVEVTSIPQTTRYEEDLTKE
                     HGTREVVKEGKNGSRTVTTPYILNATDGTTTEGTSTTDEAEMEKEVVRVGTKPKEKLA
                     PVLSLTSVTDNAMLRSARLTYHLENTDSVDVKKIHAEIKNGDKVVKTIDLSKERLSDA
                     VDGLELYKDYKIVTSMTYDRGNGEETSTLEETPLRLDLKKVELKNIGSTNLVKVNEDG
                     TEVASDFLTSKPVDVQNYYLKVTSRDNKVFRLTVEKIEEVTEEGQPLYKVTAKAPNLI
                     QHTDATKMQDEYVYYIEKTRATDGDIYYNFNDLVNAMNKNKTGTFKLGADLNATGVPT
                     PAKSYVTGDFRGTLTSVDGEHYTIHNTSRPLFNNIIGGTIKDINLGNVNIHMPWANNV
                     ASLANIIKGGTTIENVKVTGNVLGKDWVSGFIDKIDSGGTLRNVAFIGNVTSVGTGGS
                     FLTGIVGENWKGLVEQAYVDANIRGKKAKAAGIAYWSQNGGDNYAVGRYGAIKKSVVK
                     GSIDVEKPIEVGGAVGSLNYLGYIEDTVAMMKVKNGEIFYGSHDIDTDPYYTGERVNR
                     NFIVDGVSEGKSSYKYSKQQNRIKSVSQEEADKKIKELAITADKYAITEPIVNKLNAL
                     TTRDNEYRTTQDYKADRELAYRNIEKLQPFYNKEWIVDQGNKVPSNSKLLTTEVLSVT
                     GMKDGQFVTDLSEIDKIMIHYADGTKEEMNVTAVADSKVKQVREYDVTDLGVVYTPNM
                     VDKNRDQLIADVKAKLSSVELISPEVRALMDKRGKAEENTEGRQNGYIRDLFLEESFA
                     EVKAGLGKLVKALVENEDYQLNSDEAAMRALIKKVEDNKAKIMMGLTYLNQYYSFKYA
                     ELSIKDIMMFKPDFYGKNVNVLDFLIKIGSSERNVKGDRTLEAYRETIGGTIGINELN
                     GFLHYNMKLFTNHIDINDWFKKAIEKNAYVVEQPSTNPAFANKKYRLYEGINNGQHGR
                     MILPLLNLKNAHLFMISTYNTISFSSFEKYGKDTDEKREKFKSEINKRAKEQVNYLDF
                     WSRLATDNVRDKLLKSQNVVPTPVWDNHNSPNGWASRHGHIDGKPDYAPIREFFGRIN
                     KYHGYKYGYGAYAYIFAAPQPMDAVYFVMTDLISDFGTSAFTHETTHINDRMAYYGGH
                     WHREGTDLEAFAQGMLQTPSVSNPNGEYGALGLNMAYERQNDGNQWYNPNPNKLKSRA
                     EIDHYMKNYNEALMMLDYLEAESVLPKLKGNNDRWFKKMDKQMRKDGQPHQFDKIRDL
                     NNEEKKIQLASIEDLVDNNFMTKHGAPGNGTYNPSDFSSAYVNMNMMTGVYGGNSSDG
                     APGAASFKHNTFRMWGYFGYENGFIGYASNKYKAEANKAGQTLSDKYIINKVSGGTFN
                     TLEAWKKEWFKQIKTKAQKGFTAIEIDGKTIDSYEKLKDLFDKAVEEDLKGTGTDKTV
                     KLKEKVYKQLLKNTDGFSGDLFTAPQA"
     gene            complement(55596..56159)
                     /locus_tag="VWX48_000057"
     CDS             complement(55596..56159)
                     /locus_tag="VWX48_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU9170791.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(56275..57966)
                     /locus_tag="VWX48_000058"
     CDS             complement(56275..57966)
                     /locus_tag="VWX48_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9170792.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRVETS"
     gene            complement(57963..58700)
                     /locus_tag="VWX48_000059"
     CDS             complement(57963..58700)
                     /locus_tag="VWX48_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9170793.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            complement(58968..60080)
                     /gene="msrB"
                     /locus_tag="VWX48_000060"
     CDS             complement(58968..60080)
                     /gene="msrB"
                     /locus_tag="VWX48_000060"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9170794.1"
                     /translation="MNDKLKIFLLLGVFFLSITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKTVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            complement(60091..60657)
                     /locus_tag="VWX48_000061"
     CDS             complement(60091..60657)
                     /locus_tag="VWX48_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU9170795.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            complement(60677..61387)
                     /gene="ccdA2"
                     /locus_tag="VWX48_000062"
     CDS             complement(60677..61387)
                     /gene="ccdA2"
                     /locus_tag="VWX48_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9170796.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            complement(61606..62466)
                     /locus_tag="VWX48_000063"
     CDS             complement(61606..62466)
                     /locus_tag="VWX48_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU9170797.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            complement(62645..64699)
                     /locus_tag="VWX48_000064"
     CDS             complement(62645..64699)
                     /locus_tag="VWX48_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU9170798.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            complement(64711..64965)
                     /locus_tag="VWX48_000065"
     CDS             complement(64711..64965)
                     /locus_tag="VWX48_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170799.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            complement(64958..65515)
                     /locus_tag="VWX48_000066"
     CDS             complement(64958..65515)
                     /locus_tag="VWX48_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9170800.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            complement(65499..66455)
                     /locus_tag="VWX48_000067"
                     /pseudo
     CDS             complement(65499..66455)
                     /locus_tag="VWX48_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            66547..66906
                     /locus_tag="VWX48_000068"
     CDS             66547..66906
                     /locus_tag="VWX48_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU9170801.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            67117..67973
                     /locus_tag="VWX48_000069"
                     /pseudo
     CDS             67117..67973
                     /locus_tag="VWX48_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(68221..74922)
                     /locus_tag="VWX48_000070"
     CDS             complement(68221..74922)
                     /locus_tag="VWX48_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU9170802.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDTKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRIYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(75124..75201)
                     /locus_tag="VWX48_000071"
                     /pseudo
     CDS             complement(75124..75201)
                     /locus_tag="VWX48_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(75227..76702)
                     /locus_tag="VWX48_000072"
     CDS             complement(75227..76702)
                     /locus_tag="VWX48_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU9170803.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            complement(76750..77055)
                     /locus_tag="VWX48_000073"
     CDS             complement(76750..77055)
                     /locus_tag="VWX48_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9170804.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            complement(77093..77569)
                     /locus_tag="VWX48_000074"
     CDS             complement(77093..77569)
                     /locus_tag="VWX48_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9170805.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            complement(78196..84615)
                     /locus_tag="VWX48_000075"
     CDS             complement(78196..84615)
                     /locus_tag="VWX48_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU9170806.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSNSEDALSISDKEKV
                     AENKEKHENIYSAMETSQDFKEKKTAVIKEKEVVSKNPVIDNNTSNEEAKIKEENSNQ
                     SQGDYTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTYDRIF
                     NGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAGSTSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHF
                     IRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLF
                     NIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGT
                     DLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATK
                     YDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKSEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQSVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKFNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPIYKGELEKGYQFDGWKISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
     gene            84836..84922
                     /locus_tag="VWX48_000076"
                     /pseudo
     CDS             84836..84922
                     /locus_tag="VWX48_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(85303..85548)
                     /locus_tag="VWX48_000077"
     CDS             complement(85303..85548)
                     /locus_tag="VWX48_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9170807.1"
                     /translation="MSRRKKAYQGRKIGSQLFATLESEARKKVGYLQVKTVAEGSNKD
                     YDRTNDFYRGFGFKKLEIFLQLWNPQNPCQILIKKLE"
     gene            complement(85485..85763)
                     /locus_tag="VWX48_000078"
     CDS             complement(85485..85763)
                     /locus_tag="VWX48_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU9170808.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(85802..86587)
                     /locus_tag="VWX48_000079"
     CDS             complement(85802..86587)
                     /locus_tag="VWX48_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9170809.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLIFFVISLKLWDKGLDSYESAGS"
     gene            complement(86589..87407)
                     /locus_tag="VWX48_000080"
     CDS             complement(86589..87407)
                     /locus_tag="VWX48_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU9170810.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(87409..88401)
                     /locus_tag="VWX48_000081"
     CDS             complement(87409..88401)
                     /locus_tag="VWX48_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9170811.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            complement(89446..89807)
                     /locus_tag="VWX48_000082"
                     /pseudo
     CDS             complement(89446..89807)
                     /locus_tag="VWX48_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
     gene            89815..89895
                     /locus_tag="VWX48_000083"
                     /pseudo
     CDS             89815..89895
                     /locus_tag="VWX48_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(90793..91482)
                     /gene="rplA"
                     /locus_tag="VWX48_000084"
     CDS             complement(90793..91482)
                     /gene="rplA"
                     /locus_tag="VWX48_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU9170812.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(91690..92115)
                     /gene="rplK"
                     /locus_tag="VWX48_000085"
     CDS             complement(91690..92115)
                     /gene="rplK"
                     /locus_tag="VWX48_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU9170813.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            92247..92384
                     /locus_tag="VWX48_000086"
     CDS             92247..92384
                     /locus_tag="VWX48_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170814.1"
                     /translation="MKIKEQTRKLATGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(92424..93140)
                     /locus_tag="VWX48_000087"
     CDS             complement(92424..93140)
                     /locus_tag="VWX48_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU9170815.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(93221..94005)
                     /locus_tag="VWX48_000088"
                     /pseudo
     CDS             complement(93221..94005)
                     /locus_tag="VWX48_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(94025..94454)
                     /locus_tag="VWX48_000089"
                     /pseudo
     CDS             complement(94025..94454)
                     /locus_tag="VWX48_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
     gene            complement(94456..95493)
                     /locus_tag="VWX48_000090"
     CDS             complement(94456..95493)
                     /locus_tag="VWX48_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU9170816.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFGFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(95591..96916)
                     /gene="brnQ"
                     /locus_tag="VWX48_000091"
     CDS             complement(95591..96916)
                     /gene="brnQ"
                     /locus_tag="VWX48_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU9170817.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(97087..97179)
                     /locus_tag="VWX48_000092"
     CDS             complement(97087..97179)
                     /locus_tag="VWX48_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9170818.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(97222..97374)
                     /locus_tag="VWX48_000093"
     CDS             complement(97222..97374)
                     /locus_tag="VWX48_000093"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9170819.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(97534..98112)
                     /locus_tag="VWX48_000094"
     CDS             complement(97534..98112)
                     /locus_tag="VWX48_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU9170820.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(98166..99566)
                     /gene="pepV"
                     /locus_tag="VWX48_000095"
     CDS             complement(98166..99566)
                     /gene="pepV"
                     /locus_tag="VWX48_000095"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU9170821.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(99579..100184)
                     /locus_tag="VWX48_000096"
     CDS             complement(99579..100184)
                     /locus_tag="VWX48_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU9170822.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            100355..101155
                     /locus_tag="VWX48_000097"
     CDS             100355..101155
                     /locus_tag="VWX48_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9170823.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKISVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(101337..102170)
                     /locus_tag="VWX48_000098"
     CDS             complement(101337..102170)
                     /locus_tag="VWX48_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9170824.1"
                     /translation="MNHKIAILSDIHGNVTALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLHFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKDYFDF
                     L"
     gene            complement(102160..104004)
                     /gene="uvrC"
                     /locus_tag="VWX48_000099"
     CDS             complement(102160..104004)
                     /gene="uvrC"
                     /locus_tag="VWX48_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU9170825.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVIFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(104044..104745)
                     /locus_tag="VWX48_000100"
     CDS             complement(104044..104745)
                     /locus_tag="VWX48_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU9170826.1"
                     /translation="MRWLFRLIGAFFFFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(104824..106056)
                     /gene="murN"
                     /locus_tag="VWX48_000101"
     CDS             complement(104824..106056)
                     /gene="murN"
                     /locus_tag="VWX48_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU9170827.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(106061..107281)
                     /gene="murM"
                     /locus_tag="VWX48_000102"
     CDS             complement(106061..107281)
                     /gene="murM"
                     /locus_tag="VWX48_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU9170828.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(107393..108172)
                     /locus_tag="VWX48_000103"
     CDS             complement(107393..108172)
                     /locus_tag="VWX48_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9170829.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(108241..109902)
                     /locus_tag="VWX48_000104"
     CDS             complement(108241..109902)
                     /locus_tag="VWX48_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9170830.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(110077..112299)
                     /gene="recJ"
                     /locus_tag="VWX48_000105"
     CDS             complement(110077..112299)
                     /gene="recJ"
                     /locus_tag="VWX48_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU9170831.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNTVLPEGVPVLDFPGELPNLAASEAVVVKNIPESITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            112576..113334
                     /locus_tag="VWX48_000106"
     CDS             112576..113334
                     /locus_tag="VWX48_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9170832.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            113345..114139
                     /locus_tag="VWX48_000107"
     CDS             113345..114139
                     /locus_tag="VWX48_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9170833.1"
                     /translation="MKKKFFLSALLISLFGLVAAKPVQANTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIHYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            114152..114829
                     /locus_tag="VWX48_000108"
     CDS             114152..114829
                     /locus_tag="VWX48_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9170834.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            114839..115498
                     /locus_tag="VWX48_000109"
     CDS             114839..115498
                     /locus_tag="VWX48_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9170835.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            115735..116859
                     /locus_tag="VWX48_000110"
     CDS             115735..116859
                     /locus_tag="VWX48_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU9170836.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(117257..118138)
                     /locus_tag="VWX48_000111"
     CDS             complement(117257..118138)
                     /locus_tag="VWX48_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU9170837.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(118279..119607)
                     /gene="vncS"
                     /locus_tag="VWX48_000112"
     CDS             complement(118279..119607)
                     /gene="vncS"
                     /locus_tag="VWX48_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU9170838.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     HTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(119604..120260)
                     /gene="vncR"
                     /locus_tag="VWX48_000113"
     CDS             complement(119604..120260)
                     /gene="vncR"
                     /locus_tag="VWX48_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU9170839.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(120309..120392)
                     /gene="pep27"
                     /locus_tag="VWX48_000114"
     CDS             complement(120309..120392)
                     /gene="pep27"
                     /locus_tag="VWX48_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU9170840.1"
                     /translation="MRKEFHNVLSSGQLLTYKRPARDYNRK"
     gene            complement(120573..121952)
                     /gene="vex3"
                     /locus_tag="VWX48_000115"
     CDS             complement(120573..121952)
                     /gene="vex3"
                     /locus_tag="VWX48_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU9170841.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(122004..122651)
                     /gene="vex2"
                     /locus_tag="VWX48_000116"
     CDS             complement(122004..122651)
                     /gene="vex2"
                     /locus_tag="VWX48_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU9170842.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(122664..123941)
                     /locus_tag="VWX48_000117"
     CDS             complement(122664..123941)
                     /locus_tag="VWX48_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9170843.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT        36177 a        27348 c        22440 g        38048 t
ORIGIN      
        1 tggaagaggt catgaatcaa ctccaagatg tcatacaagg actggagaag gaggtgataa
       61 agtccatcgt taatcggaga tggactagaa tgctttttga aagcagatga gtattatatg
      121 caatttcttt atataaaaag accggattgc tccgatcttt caatagttca tattctcaat
      181 ttctatttta aaaatagcta aggttaacgt caaatgacta cgcgacctat ttcatacgat
      241 aaaaatcaag cactagacca gcaggtcctt gaactaataa ggactctgtt ccccaatcgg
      301 ttacagttgg tccgtgtaaa acctttatac caagctcgtt caaccgtttg tagttctggt
      361 ctacatcctc aacctcgata tgaataatga ttcctgactg aaagttttcc aaaggaacca
      421 aatgattttg tgacaacata aggcagtgac taccaatcgt aaactgagca aaaccatcat
      481 cagcataatc tgccttttta tccaaaatat gctccaagtc agcacagact tggggaacat
      541 ttgaaacgat aatatctaat tgatttaaat tcatttactc tcctccataa aaagaccgga
      601 ttgctccgat cttttaaagt tctgctctat gaaaatcaaa gaataaagtc tacaagtttc
      661 atatttgatt ttcggcgaga ggaattattt aattgcgcgt gattgcaatc cttcttcttc
      721 caagaagaga cggaatggta cgagttcttc tgcttcgtat ttttccttga aggctttgat
      781 agcttcttct gagtgaagtt ttggatccaa ttcaagtact tctactggaa gtggacggtg
      841 ttgagtgatg cgagcatcga tgacaacagt tttaccttct ttgttcaatt taacagcttc
      901 tgcaacaact gcatcgatgt cttcgatacg gtcaactgtg aatccaacag ctccttgagc
      961 ttccgcaatt ttagcgtagt cagcgtttgt gaagtctaca ccaaacaagt gtttgtttgt
     1021 atcttcgtat ttgttcttga tgaagccgta ctcagcattt gagaagacaa ggttgataac
     1081 tggaaggtcg tattgaacgt ttgtgataac gtctgggtag cacatgttga atgctccatc
     1141 acccatgatg ttccatactt ggcgatctgg attgtctttc ttagcagcga taccaccagg
     1201 aagggcaata cccattgtcg caaagagcgg agatgtacgc cacatattct taggtgtcat
     1261 gtgaaggtga cgagtagatg tttgagtagt gttacctacg tcgattgagt agatagcgtc
     1321 ttgatcagca tgtttgttga ttgcattgta aacttgatac aattgcaatt caccctcagt
     1381 tttaccttcg agtttgttca tgtaatcacg ccagttttgg ttgttcttaa cgtttgcacg
     1441 ccaccatgga gttgattcaa ctgggtttac tttgtcaagg atagctttag ctgcttgacc
     1501 agcatcacca aggattgaag cgtcaagggc atgacgttta ccaagtttgt aagggtcgat
     1561 atcgacttgg atgaattttt cagtgttctt gaatgcttcg taaacttcag caaatgggaa
     1621 gtttgaacca aggaaaagaa ctgtgtctgc ttcaaagacc acttcgttgg ctggtttcca
     1681 accaacacgg taagcagaac ctgtcaaacc ttcatagttc cattcgaaag cttcaaagtt
     1741 tttaccagtt gtgatgattg gtgctttgat tttacgtgac aattcagtaa tcacttcacc
     1801 agctttaaca ccaccaaatc cagcatagat aactgggcgt tcagcattgt tcaagatttc
     1861 aacagctttg tcgatttcaa cttcgttcaa agcaggagcg atgaatgagc gttcgtatga
     1921 acctgaaccg tagtatgagt tttcatcgat ttcttggaaa ccgaagttta ctggaatttc
     1981 aacaacagct ggaccttttt tagaaactgc agcacggcag gcttcgtcaa ttacttttgg
     2041 caattgctca gcgtaagcta cacgtttgtt gtaaacagcg ataccgttgt acattgggtt
     2101 ttggttaagc tcttggaaag catccatgtt caattcgtta actggacgtg atccaaggat
     2161 cgctaggaat ggagtgttat ccatagctgc atcgtaaaca ccgttaatca agtgagtcgc
     2221 acctggacca cctgaaccaa ctgcaacccc gattgagccg ccgaatttag cttgcataac
     2281 cgctgcaaga gcacctgtct cttcgtggcg aacttgtaag aaacggatat ctttgtcttc
     2341 agccaaagcg tccatcaatg agctgagtgt tcctgatggg ataccgtaga ttgtatctac
     2401 gccccatgtt ttcaatacgt taagcattgc tgcagatgca gtaattttcc cttgagtcat
     2461 aatgataact ctccttcaat ttttttagac ttggagaata cgattacata gaattggaaa
     2521 cgttctccaa atttttacta ttccactgta tcatatttat gctgactttt ctaaaaatct
     2581 gctcaaaact ctctattctc tattctaata cagttttgaa ggtgttgtca tttttgtttt
     2641 ataacaaaga aatctagtca ttacttttag tctattttac taaaatttaa cagaagggaa
     2701 ctggtcagaa cagatacaga actaaaggcc atggctagac ctgccaattc tgggttgaga
     2761 gccagtccaa cacctgaaaa gactcctgct gcaatcggaa ttccgacaac attgtagata
     2821 aaagcccaga aaagattgag tagaattcga tgaaaggttt tcttactcat atcaaaggca
     2881 cgcaccactc ctaaaagatt attggttgtc aacaccaaat ctgctgactc gatggcgata
     2941 tctgttccag ctcccatagc aatccccaca tctgctacac taagggcagg agcgtcattg
     3001 atcccatcac caacaaaggc tactttacct gactgttgca gtttatggat ttcatgggct
     3061 ttttcttctg gcaagacgcc tgcaatgacc tcttcaattc cgatttgatc tgcaatagca
     3121 cgcgccacac cagcattgtc tcctgtcagc atgactgttc ggagaccacg tttttttagc
     3181 tgactgatga ctagcttagc attttcctta ggaatatctt gcaaagcaag caaacctttg
     3241 atttcattgt caacagctaa gaacacaact gtcttagctt ctttttctag ttcttctagt
     3301 ttatcttgat aagtattaga aatatccatg ccatccagca ttttagcatt tccaagtaaa
     3361 acttgttttc cattaattcg ccctgaaaca cctttcccgt gcaaggtctg aaaattttca
     3421 acagtttgaa actcaagtcc agcttcactc gctcgcttaa cgatagcctc agccagtggg
     3481 tgttgagaag catcttccaa ggaggctgcc aacccaaaca cttctacttc gtcgccgatg
     3541 atatctgtta ccacaggttt cccttccgtc aaagtcccgg tcttatcaaa gacaagagtt
     3601 tgaactttct ggatttcctg taagacagtt ccatttttga ggagaacccc catcttggca
     3661 ctacgtcctg tccccaccat aagggctgtc ggtgttgcaa gtcccaaggc acaaggacag
     3721 gcgataatca aaaccgccac tccgtagaga agagaggaca caaagctagc tccaagcacg
     3781 accacactat ccctgagcaa gacgaaccaa acccaaaagg tcatgattcc taaaatgaca
     3841 actactggga caaaaatccc tgaaatctta tccgtcaagt cctgaatcgg cgcacgactt
     3901 gtctgagctt tcttcacaaa atctacaatc tgagccaaaa cagtctctga gccaactttt
     3961 tctgctctaa agacaagcgt tccactatga ttgatggttg agccaatgac agtatctcca
     4021 actgtcttgt ccacaggcag actctcacct gtcaccatgg attcgtcaat actagagaca
     4081 ccttctacta cgacaccatc aacagcaatc ttttcaccgg gacgcactcg aatcaggtcg
     4141 cctaccttga cttgttccaa aggaacttgg acataactat catcactcaa gacttctgcg
     4201 gttttagctt gcaagtccag taatttctcc acagcttggg acgtattttt cctcattttt
     4261 tcctcaaaaa ctgctcccaa aagaacgaaa aagaggataa atccagcact ttcgaagtaa
     4321 acagggagac cagcaaagag agcaactagg ctatagaaat aagccactag agttcccagc
     4381 gcaaccaagg tatccatgtt ggcattgtgc tttttaaaac tggcccaagc actctggata
     4441 tatggcttac ccgcaactaa cataataggc gttgttgcta aaaaggttcc ccaatgcatg
     4501 acttgatgac taatgctacc tgccaacatc ccaatcatga gaatcacaag aggcacagta
     4561 aagatactag taatccaaaa acgttgcagg agagatagag attttcgagt cttctcaacg
     4621 actatatagc ttcccttttg catcttcatg ccacaagaaa attcatgtct ccctaattct
     4681 tgaggtgtaa aacgaatgac tttctcctca tctacgccga ttgcttccaa gataccttct
     4741 tcttcaaaca gaatttcctt ataacagttt gaaggagtag cacgatgaaa ggtaatctca
     4801 gctggaattc ccttttgaag ctggatatgg gctggatgat agcctttttc agctcggata
     4861 cggatttttt gaatgccatt ttctaagctt gctttcacaa tttctgtcat agtctccacc
     4921 tactctacaa tcatcttgcc gtgcatcatg ttcataccac aagcaaagcc aaactctcca
     4981 gcctgttcag gcgtgatttc cactacatac tcttccccca ttggcaggtt cgcatgtaca
     5041 ccaaaatctg gaaaaacaat ttgatccaga catggtgaag gatccttgcg gtcaaagaca
     5101 atgcgggctg gcactgattt cttgaggaca atcaactcag gagtatagcc tcccatgact
     5161 tccactcgaa tctcttggta tccgtttttt tgctgggctt tttgtccaga tttttcaggc
     5221 tttttgaaaa accaaaacaa gataaacgcg ataagggcaa tacaaataat ggttacaata
     5281 ctatttaaca tgacgtctcc tttacataca attacatctt acttctgtta cagcacttga
     5341 tttcttctct gaaatcacag cttccaagtc ttccaagtca gtctgagtaa attcacattc
     5401 tacaatcaag tcagccaaca aattcctaat cctacgggaa caaaccttgt ctttgatatc
     5461 ttggacaagt aaatcccgac tttggtctag agttaaaagc gctgaataaa caaaggactt
     5521 gccttctttt ttccgagtca aacactcttt ctcaactaga cgagccaaaa gtgtctgaac
     5581 cgtggacttg gaccagtcaa accgctctgc caaaacccta atcaaatctg tactggtctg
     5641 ctccccctgc atccaaataa tcttcatgac ctgccattct gcatctgaaa tctgcattac
     5701 catacctcca aaatctacat ttgtcaatta cactcaacag tatactccca aaatctacat
     5761 ttgtcaatta tagaaataat attttcttcg aaaaatagaa ttttaatcat ttgaaaaacg
     5821 atttgcagtc aaatattact atataaacaa taaaaatatg ctatactaaa gaaaaaagaa
     5881 aacaaccact aggggtgcgt aaagctgaga ttaacgactg ttagatccct ctgactcaat
     5941 ctaggtaatg ctagctgatg gaagtggaaa tgataatggg gactagcagt cttctattgc
     6001 ctttctaaaa cagactagct tgttcttaag aatacaaact tcagttggtt gggaggtttt
     6061 agatgactta tttacccgtt gctttaacca ttgcagggac tgaccctagt ggtggtgctg
     6121 gcattatggc agatttaaag tcattccaag cgagagatgt ctatggaatg gctgttgtaa
     6181 ccagtcttgt cgctcaaaat accagaggtg ttcagctaat cgagcacgtt tctcctcaaa
     6241 tgttgaaagc ccaattggag agtgtctttt ctgatattcc acctcaggct gtaaaaactg
     6301 gaatgttggc tactactgaa atcatggaaa tcatccaacc ctatcttaaa aaactggatt
     6361 gtccctatgt ccttgatcct gttatggttg ctacaagtgg agatgccttg attgactcaa
     6421 gtgctagaga ctatctcaaa acaaacttac tacctctagc aactattatt acgccaaatc
     6481 ttcctgaagc agaagagatt gttggttttt caatccatga ccccgaagac atgcagcgtg
     6541 ctggtcgcct gattttaaaa gaatttggtc ctcagtctgt ggttatcaaa ggcggacatc
     6601 tcaaaggtgg tgctaaagat ttcctcttta ccaagaatga acaatttgtc tgggaaagcc
     6661 cacgaattca aacctgtcac acccatggta ctggatgtac ctttgctgca gtgattactg
     6721 ctgaactagc caagggcaag agtctttacc aggcagttga taaggccaag gcctttatca
     6781 caaaagctat tcaagatgcc cctcaactcg gtcatggttc tggtccagtc aaccatacaa
     6841 cttttaaaga ttaagaaaaa aactctctag ttcccacttt aagggaatta gagagttttt
     6901 atacccttcg aaaatctctt caaactacgt cagcttccat ctgcaacctc aaaacactgt
     6961 tttgagctga cttcgtcagt cttatctaaa acctcaaggc agtactttga gcaacctgcg
     7021 actagctttc tagtttactc tttgattttc attgagtatt aattaggaaa gaatgtcatg
     7081 caactttgtt aaaaaggctt gcgtttttgc ctcaatatct tctgcttgca tcaaatcacg
     7141 tacaacagct acaccagcta taccagtgcc cataagctga tcaatattct ccgaagtcaa
     7201 gccgccaata gcaactattg gaatggcaac cgtttggcaa attgttttca aggttgaaat
     7261 cagggtgatg ggtgcatttt ccttggtggt tgtcggaaaa atggctcctg tccccaagta
     7321 atctgcacct gatttctccg cttccagagc tcttttaacc gttttagcgg tgacaccgag
     7381 gattttttca ggacccaaga cttgtcgggc aaccgaaact gggagttcgt catctccaat
     7441 atgcagacca gcagcatcaa ccgcaagaca aacatccaac cgatcatcga ttatcaaggg
     7501 gacctgatag gcatctgtta tttccttgac ttgttttgcc agttgataat attgattggt
     7561 tgtgagattt ttttctcgca attggactat ggtaacccct gaacggcagg ccgtctcaac
     7621 ttttgcaaga aagctttcca cggaatcttg atagcgattg gttaccagat atagtctaag
     7681 cgcttctcta ttcataaacc tctcctttga tggtatctag ccaattttca tctcttctta
     7741 ggagcgaaag ctgattgagt acttggtaac gaaattcttc caatcccatt ccttgaacaa
     7801 ctattttctc agcagcgata ttgagataag agactgctaa gcaagaagct tcaaaaccag
     7861 tctttccttg gctgagaaaa acagctgtta aggctccaac caagtctcct gtccctgtta
     7921 tccagtctaa ttcagtacag ccattctcaa gtacagcaac ttgattctcc gaaacaataa
     7981 ggtccttggg acctgtgact aagaatgaca taccaggata ggtctgacac cagtctttca
     8041 agacttgaag caaatcctcc gtttcttgat ctttagcact cgcatcgacc ccaacgccgt
     8101 gatgctttaa tccaacaaga cttcgaattt ctgacatgtt tcctttaagg accgtaggtc
     8161 tatagtctaa aaggtcttta actaagctct tacgaatgga tgaagtcgtt acgccaaccg
     8221 catctactac catcgggaga gaagattggt ttgcatacaa agctgccatg cggattgctt
     8281 tttccttctc agctgacaaa tgccccaaat tgatgaagag agcctggctt tgcttagtaa
     8341 aatcaagaac ttcacgggga tcatctgcca tgacaggttt gcatcccaga gccaaaatcc
     8401 catttgccag catctcacaa gaaatctcat tggtcataca gtgaatgagg gaactagagc
     8461 ctataggaaa aggatttgtc aatgcctgca tcattctatc ctttcagcaa agaaatatcc
     8521 ttgcactttt ttaaagaatt cctgcttgat taaaaatcta aatgcaataa aggaaatcgc
     8581 tgtaccaatc aaggttgctc cgaaaaatcg aggcgtgtag ataaaccaac taagcttagc
     8641 agccgatcct gtaaagagca ccataacagg ataggaaaca atagaaccaa taatacctgt
     8701 tcccacaatt tctcccaagg cagaaaagta aaattttcga ccgtacttat aaaagagacc
     8761 tgctagaagg gctccaaaag tcgctcctgt gagagctaaa ggcggaatcc cttgagtcgt
     8821 catacggata aaggctgtca ctgtagccat agccaaggca taaacaggtc ccatcatgat
     8881 tcccgctaga atattgacta cactggacat cggtgccatt ccctcaatcc gaaagatagg
     8941 tgtaaggact acatcaaggg caatcatcat agataaaatg gtcaatttgt gaacttgtag
     9001 ttggtgcttt ctcatgtttc tattcttctc ctttttctaa agactgtaaa tcgctcttcc
     9061 atgtctggtg ttggtaagcc atctcccaaa acttggcttc catatgaaca ctgatgtgga
     9121 aggcatctag cattttttgc ttatctgtct catcactttc tcgatagagc tgattgacca
     9181 gtgctccctc ctctctgatc tgttgctcta actcatccgt aatataagtt tcaatccatt
     9241 gttgatagag aggatttggt gatggtttaa gattaagtga tttgcctata tcatggtata
     9301 accaaggaca aggaagcaag cttgcaaaag cgatggctaa gttcggttct gcaaattgcc
     9361 tataaatatg agaaatgtaa tgataacagg ttggagcaat tggatgttgc tccatttcct
     9421 ggtcgctgat ttccatttcc ttgaaaaatt gttggcgaat aaataactca ccctccacta
     9481 aaccctgagc attttgtttc aagagtcttt tcatctcttg gtttgaagtc ttatcagcca
     9541 aaagatgata gatttctgag aaggccttca gatagtaggc atcctgaatc aggtaatagc
     9601 ggaaaatggc aggttctaaa ttcccctctt gtaattgtaa aataaaggga tgatgaaagg
     9661 aagcctgcca agctttcttg gataattcca tcgcaatatc tgtaaattcc ataataactc
     9721 ctttataaaa atagactggt ttgaagcaat aaaaagaaaa gcaggtagat taattttgtt
     9781 tttttaggaa tataaaaagt ccgatagcta ttcttaaact gtgcatgttc gtcatatcca
     9841 tgagcagaca gagctctcag gtaaagatgg cgccacctaa agactgtcat cagaacctta
     9901 ctgtaaatca agggcgacca aaaatgcagt tcttgaccac gtaatagaca agcttctttg
     9961 agggacttga tttcttgctg aatgagagga aaggaattga ataccacaat caaggcatag
    10021 gaccaagagc gtgatagccc cttttgagcc aagtacaaga gaagctcttt tagtgaaata
    10081 gaggaaacaa agacaaggcc gatacaaact gtcacaaagg ccctcgttcc aagcatgact
    10141 gcctgtgaag catctccgtg taactgaact gcccagtagt tggcaaaaga tggtaaaatg
    10201 gcaagtatga tcatccaagc taacatttta aatcgacggt aatagagcat aaagagaata
    10261 caaaatgcga ctaccgaaag attcagagca atcgaaggaa tgaaagatgt ttccaaggat
    10321 aaaatcagca agaagagact gataatcggt gtctgggttg ctactttgac catactatct
    10381 cacctcccct tgggtattgc tactctgaga tgtaagtggt ttggtaatgg tcacttcttt
    10441 cacatgccga agaccctgac tagtcatctc aatccaataa tcaaccacag aaatcaaagg
    10501 gtctaaacga tgactaatga gcagaaaact tcttccttga ttcctctcct ccacaatcca
    10561 cttgcaaaaa taatggcagg ctctatcatc caaacctgca aaaggttcat ctagcaagat
    10621 cacggaagcc ttactggtca agatggtcag gagctgaaga attttttgct gaccaccact
    10681 taattgatag ggactcttat cgactgcctg ctccaaatca aaatatcgta aagcttgaaa
    10741 aatccgctga tttctttcag aatcaggtcc atctaattga agctcctctc gcagactgac
    10801 tcggataaac tgcttctcag cttcctgaac aatactcgtc agatcacggt acaaactctt
    10861 tttctttttc aggactgtcc ccttccatgc aatgcgcccc ttatactttt gaaattgaag
    10921 aatagaccga aagagggttg atttcccgac accattgtca cccaggatac aggaaatccc
    10981 ttgatagaat gtgaaatcag caattgaaaa gagggggcga ttaccaagct caccagtcac
    11041 acggttcata tggaatagtt ccgggctaga agcaacttcc tttgaagcaa cctgtgtcat
    11101 ctcataggaa gggatttgaa acacttccct tagttttccg tctcttagct caaccatatg
    11161 gtcgatatag gctttatagt cagataaatc atggtcgcac aaaataactg tcttcccatc
    11221 aagagccaac tcttttagaa tctccaatat ctcgattctg ctcttgcggg caatagaagc
    11281 gaagggctca tccaagagat agaccctagg attcatggca aagaggacag ccagcgctgc
    11341 tttttgcttt tccccacctg ataggtgatg aatgggacgg tgtaagattg cctcgcaacg
    11401 acattgctgg acaacctctg ctattttaga atcaatttcc tgaaggtgat agccgatatt
    11461 ctccaaggtg aaaatcaact cctcaaacaa gttctccatg gtaaattgat gattgggatt
    11521 ttgaaagaga atgccaacct tctggacacg ttcgacgata gaaagctgac tgacctcact
    11581 cccatctatc aggacttgac cgctataggg aagagaacta acttgggcaa tcatttgaaa
    11641 gaggcttgat tttccagacc cactactccc aactaacaag gtaaaggctt gcacatgaaa
    11701 agtaaaatca aacggctcag agaagattgg ggactgaatc gctcgtagtt ccagacccat
    11761 ctatgctttt cctccagttg caaactgatg atagagtttg acaatggcac gaaccaagat
    11821 ggtacagaag aaataaacag aaataaaacg taccacaagc aaggaaagga caaacgaaag
    11881 ggaaaaggcg tagtaaccta acttaatgta ttcatagaca aagctaacaa gcgtaatccc
    11941 aatactatta gcagttagag agagccaact ttcatagcga ttcttagtta cgataaaacc
    12001 aaattcactt cccaaacctt gaaccaagcc agacaaaaga gctcctagac caaattggct
    12061 accataaagg acttcagcaa gcgcagctag cacttctcca atcattgcac ttccgactct
    12121 cggaacaaag atggcagcaa tgggcgcagc catacaccag agaccgaaga ggatttcatt
    12181 ggcaaaggcc tgcaaaccaa gaggtgttaa gagtagactg agaatattat acacatatcc
    12241 tgaaccaacg aaaaccccac caaaaaagat agacaagaaa gcaagcaaga taacatcttt
    12301 taactgccat tttttcaaca taaaaaactc ctttttttaa agaaaagtgg ggcactcaag
    12361 aagaccgacc taaatacttt gtatagcaga ctgaatttag aacagtacac aagaatgcta
    12421 aaatatttct agaaattaat ttgaattttc taattgattt gttcgcatct tatttcaatc
    12481 tactatatca tcttcatcca gtttcgtaaa agaaaaaact ctaattacag atacgaatta
    12541 gagttcagct tacaagatta gacagttctt ttcgacatac gaaaaaaaca tttcacattt
    12601 cccttcgcca gtcttaactg tatcaggttc aatgggtatc atctcagcct aaagcacccc
    12661 aaatgtcttt attatttaat tatgtgatta ttataacaca cattttatac tagttcaaga
    12721 aattgaactg gaaatacagc cttgcactca caaagacagc agatctttct tttgcaaaaa
    12781 acaaatgacc tgtttgatga attagccatt caagctgaat ctagacatag ctttttaaaa
    12841 aaggaaaatc ctacttactt agaatccaag gatagatatc tattgttcac tcatttcccg
    12901 aacagttttt tctatatttt ttgcatacga tattgccgaa atgattgaaa cgccgtcaac
    12961 attggtcttt ataatgtctt taatatgttt cgtctgtatc ccaccaattg caactaaagg
    13021 catttgtggc aatagttttc tcatcaattc aagaccttca taacctatag caccaccagc
    13081 atcatctttt gactgggtat caaatacagg cccaacacct acataatcta catattcaac
    13141 ttttgattgt tgaaattctt cttcgtttct tatagaaaga ccaattattt tatctggcat
    13201 caattttcta atttcatcaa caccaatatc atcttgacca acatgtacgc catcggcgtc
    13261 aatttccatt gctaaatcta tatcgtcatt aacgataaat ggaacattgt attttttaca
    13321 aagttcttta atttggatag ctagctcaag tttttctaag ccttctaaag caccctcacc
    13381 tttttctcga aattgaaata aggttatacc accttttaag gcttcctcaa cgactgtata
    13441 tagatttttt ccttggcaag tagtcgttcc acaaataaaa tatagtttta gtaattcttt
    13501 atgaaacatc ttacttcact cttttgaatt cctttacatc ttcatctgta atctcgtata
    13561 aggcatttat aaattcaact ttaaatgtcc caggaagatg tccatttgga cgtttttctg
    13621 ccatttctcc agcgatattg taaactaaca ttgctgtttc taatgatttc aattcttgac
    13681 ctttttctag tccgataaag cttgctacta cagctcctaa taagcatcct gtcccaatga
    13741 ctttcggcat catagcacta ccattatgaa tcgttaccac ttctccatta acagcaatgg
    13801 catccacttc acctgttact actattggaa tattgaactt ctcatttgct gctagagcaa
    13861 tttcgtcaat attatctacg cccgcactat ctactccttt agatgccaca tctattccta
    13921 ctaaagaggc aatctcgcca gcatttcctc taatcgctgc tagtttataa ttgttgatta
    13981 gatcatctgc tacttttttt ctatattctc ctgctccaca ggctacagga tctaaaactg
    14041 ctgggacatt atatttctcc gcaattttca gagcagcttg gtataatttc caattttcat
    14101 ctgtcaatgt tcctatgttt attaataaac caccagcata ctttaacaaa tcctctaaat
    14161 ctgctggaaa ctcactcatg gctggtgaga cgctcagtgc tactaatcca tttgctgtga
    14221 aattttttac tacatcattg gttatacaaa tgaccaatgg tactttttct tttaataatt
    14281 ttaaacttgt catattgaaa tccttccttt acactttata cgatctactg atttcgattt
    14341 atctctatct ttcgttaaga aatttttttc atttacgttg aatgatttat actcaatgaa
    14401 aatcaaagag caaactagga ggctaaccgc aggttgctca aaacactgtt ttgaggttgt
    14461 ggatagaact gacgaagtca gtaaccatac ctacggcaag gtgaaactga cgtggtttga
    14521 agagattttc gaagagtctt acctcatcaa atttgtaaat atcatgagcc ttctctagac
    14581 atcgtaacca atatcaaaaa aagctaattc taaagcgact gcttgattcc agcgttgctg
    14641 aagttctgtc aaatcttctc gatttttacc gacacgattg agttcgtcaa ccagaaattg
    14701 aacccactct gcaaagaaag gacctctgtg gagattgatc cattccgaat gaatataaac
    14761 ttcaggtaga gcaaaatctt tagaacccca gtctaaatag agaccttctg caatgaccag
    14821 cataaccaaa agatgggcat agtctgatga agccactgcc gaatacatta gatcctgaaa
    14881 ggcttttgtt acagggtgca aagtcacttc taggtagtca ttctctgcta cttttaactc
    14941 tttaaaagcc ttttggaaat aaccatcttc atctgcttca agaaagccta gttgcttggc
    15001 aaaacgaagc ttggattcaa gtttatctgc gtgagctacg caggcaccca gcatggataa
    15061 gaaggcatca aagaagtgat aatcttgaat cagatagtcc tttaagacct tattctcaat
    15121 tgtccccgca aaaagttcct taacaaaacg atgattgatt gcagcctgcc aatccttctg
    15181 actgcttttt aataattctc caacagtcaa acctggctga aatgcatagt cttgtgtttc
    15241 catatttact tctcctctct ttacttgtta gtaattaata aaacaccaag aaatatcaag
    15301 caaaatcgta attccacttg atccttttaa aacacatcga gagtatttgc agagagctaa
    15361 ctaaacaagc ctatccagtt tatataaaca aaaaactcca attacaatca agaattagag
    15421 ttgacttaca agattagacc attcatttca ccatacgaaa aaactgttca catttccctt
    15481 cgccagtctt aactgtatca ggttcaatgg gtattatctc agcctaaagc accccaaatg
    15541 tctctattat ttaattactg aaccagtata gcaaaaaatg aaagccttag caagatattt
    15601 aaccgaaaaa tatctttata tatagtagat tgaaactaga atagtacccc tctacttcta
    15661 aaacattgtt agaaatcgat ttaactgtcc tgattgattt gtcctattct tatttcattt
    15721 tactatagtt ttcgatagca atttattctt ccaatacacg aagaaaaacc tccacattca
    15781 gtggaggcaa tctgttttat caatacaatt ttaagtcacg agggtcaact gggaaggttg
    15841 ggttgtatgg attgtgacgg agcttaaagt gtttgacatc ttcaatggtc tgagctccag
    15901 acaattgcat aactgtcttc aattccgcat tcaagtgttc aaagacttga cgcacaccga
    15961 cactaccacc gagagccaag ccataaataa cagggcgacc aatagctacc aagtctgctc
    16021 ctgaagccaa ggctttaaag acgtgttgac cacgacgaac accagagtca aagacaatcg
    16081 gcacacgtct atcaactgct tctgccactt cttgaagcga gtcaaaggca gctggtccac
    16141 cgtcgatttg acgaccaccg tggttggtta cccagatacc agaagctcct gcagcaagcg
    16201 aacgttcaac gtcctcacgg cattgtggtc ccttgacata cacaggaaga ccagagtatt
    16261 cagcgataaa ttctacatcg cgtggagaca agcgttgttt agctgatttg taaacaaagt
    16321 ccattgattt accagcacct tctggcaggt attcttcaac aatcggcatg ccaactggga
    16381 agacaaaacc attacgctta tccacttcac gattcccccc tacagtagca tctgccgtca
    16441 agacaatcgc tttataacct tcagccttca cacggtccat gatgtggcgg ttgataccgt
    16501 catccttact aaagtaaaat tggaaccaat ggggggtccc ttgaagggct tcagaaatct
    16561 ctggaaggtc aacagtagag taagagctgg ttgtataaag agaaccaaac tcatgcacac
    16621 cacgcgcagt cgccacttcc ccctgttcat ttgccaattt atgagccgca acaggcgcca
    16681 taatgattgg tgaagatagt ttttcacctg caaattcaat ctctgtactt ggattttcaa
    16741 catcgcaaag tgtatgagga acgatgagtt tgtggttaaa ggcgcggata ttctctctta
    16801 aagtgaaagt atcttccgcc ccactagcga tatagccaaa tgctgcttta ggaataactt
    16861 gttgcgccat tggctccaaa tcataggtat tgatgaagtc tacatgacct tctgcattgc
    16921 ttgttttgta tgacataaaa tgccctcctt gattaagtaa gcgtttgctt tttactacac
    16981 aactataata actctttttt caatcatttt caagagtttt gcttaaaaac catcttattt
    17041 tttcatacaa tatactagcc ctactttcct taaactctaa accttagtct atattaagtg
    17101 aatcgttgag attttttgct gccaggcatt tgaactactt ttttatttgc ggattctatc
    17161 tactaatact ataaaaaaac aagtgaataa gacaccagaa catcctctaa taggacctat
    17221 ggacttatat cagtcccata tatactgttt aagcaagata ctatcctagt tgacgctaac
    17281 ttcctatccc acttattaat tttttattta tagtgaatct gaacaaatca attggggaat
    17341 ccaagtcaat ttctagtact ttttgaacag tttcagcgta ctatcgtaaa atgaaataaa
    17401 acatgcacaa attgattagg gaatttaaac caatttctaa caatgtctta gaaatcaaag
    17461 tgtactattt caacttcaat atactacact tcattttctc cttaaattca gtctcttttt
    17521 gaatcaaaaa atcctctggt aagagccaga gggtaagaat ttatttcatt gttgggaaga
    17581 gcaatacatc acggatagtt gttgtatcag tgaggagcat gcagagacgg tcgataccga
    17641 ttcccaaacc acctgttggt ggcataccgt attcaagagc ctcgatgtag tcatagtcga
    17701 tgcctgtcgc ttcatcatca ccaagttctt tagctttagc ttgggcttca aaacggctaa
    17761 gttggtcgat tgggtcgttc aactcagtaa aggcattacc gtactcctta gtcatgataa
    17821 agagctcgaa acggtcagta aagcgttggt cttcaggatt tttcttagcg agtggagata
    17881 cagctactgg atgtccatag acaaaggttg gttggattaa agtttcttca acaaactctt
    17941 caaagaaggc attgatgatg tgaccaacct cagtgtagtg tttctcaact ggaactttct
    18001 tctcagcagc gatagcttta gcttcttcca aagtcatgtc ttgccagaaa tcgacaccag
    18061 taatttctct gatagcatcc accatatgaa cacgcttaaa tggttcgtta atcttgattt
    18121 cagtaccttg gtagttgact gggccatcac ctttgactga tttagcagcg tgttggataa
    18181 tgccttcagt caagtccatg atgtcttgga agtctgcata agcttggtaa acttcgatag
    18241 aagtgaactc agggttatga gtagcgtcca ttccttcgtt acggaagata cggccaattt
    18301 catagacacg ttccatacca cccacgataa ggcgttttaa gtgaagctca gtcgcgatac
    18361 gaagcaccat gtcaatgttt tgggcattgt ggtgggtgat aaatggacgg gcagcagcac
    18421 caccggcttc attatgaaga acaggtgttt ccacttcaag gaatcctttt tggtcaaggt
    18481 aacgacggat ttcagagatg atttttgaac gagtgacaaa gcgttcaaag ctttcacgat
    18541 tagaaatcaa gtcaaggtaa cgtttacggt aaattgtttc aacgtctgtc aaaccatgga
    18601 atttctcagg aagaggacga agagccttag acaagtgtgt gatgtgggtt gccttgatag
    18661 agagttctcc catatccgta cgcatcactt caccttcgac accaaggaag tcaccaaggt
    18721 ctgctttttt gaagatttcg tagttttctt caccgacagc atccttacga acgtagatct
    18781 gaatctggcc ttcgcggtct tgaaggtggg caaaaccaac ttttccttta ccacgtttgg
    18841 ttaccaagcg tcctgcgata gtagctgttt cgtttttatc gtgtaattgt tctttatcga
    18901 ggttggcata tttatctttt aattcttgtg aatttgcagt acgttcaaaa cgttttccga
    18961 aaggatcgat tccttgttcg cggagcgcag ccattttttc acggcgaacg atctgctggt
    19021 catttagttc ttccatatgt tctgtagaca tgggatcctc ctagttttac tcaaaattga
    19081 atacgatgag tcattttttg cgatacccca ttttatcata aataagcaag aaattcacgg
    19141 ataatcttta aaaactaaaa agaacctgac gctaaaatca ctggaaagaa gtgaaagtat
    19201 cttccgcccc actagcgata tagccaaatg ctgctttagg aataacttgt tgcgccattg
    19261 gctccaaatc ataggtattg atgaaatcta catgaccttc tgcattgctt gttttgtatg
    19321 acataaaatg ccctccttaa taagtaagcg ttcactttgt atattacaaa aatatcttaa
    19381 ctctttttca aaacttttca aatattttgt ttggaaattt cagaaatttt atgtctatgg
    19441 taaaaaatcc ttataacggc aataaaaaat agatattatc caaagaagat tttaagtgct
    19501 acaataactg tattatttct agatgggagg ttctattttt ggattggtcc attgttgaac
    19561 aatatctacc actatatcaa aaggcattct ttctgacctt gcatattgca gtttggggaa
    19621 ttttgggatc ctttctgctc ggtttaatcg ttagtatcat ccgacattat cgaatccctg
    19681 ttttggcgca agtagcgaca gcctacattg aattgtcacg taatacgccc cttttgattc
    19741 atctcttctt tctctacttc ggtcttcccc gaatcgggat tgtcctatct tcagaagtct
    19801 gtgcaacgct tgggcttgtc tttttaggag gatcctatat ggcagaatct ttccgaagtg
    19861 ggctggaagc catcagtcaa acccagcagg agattggcct cgctattggt ctgacacctc
    19921 tacaggtctt tcgctatgtg gttcttccgc aagcaacagc ggtggcactc ccctccttta
    19981 gtgccaatgt cattttcctt atcaaggaaa cctctgtttt ctcagcagtg gctttggccg
    20041 acctcatgta tgtcgccaag gatttgattg gtctctacta tgagacagac attgcgctag
    20101 ctatgttggt agttgcttat ctgatcatgc tgctacccat ctcactggtc tttagctgga
    20161 tagaaaggag gctccgccat gcaggattcg ggaatccaag tactctttca gggaaataat
    20221 ctcctgagaa tcttacaggg attgggcgtt acgattgaga tatccatcct gtctgtcctc
    20281 ttatccatga tgttcggaac agtcatggga atcatcatga cctcccattc tagaatcata
    20341 cgatttttaa cacgattgta tctggacttt acccgtatca tgccccagct ggtgctactc
    20401 ttcatcgttt actttggctt agctcgaaac tttaatatca atatctcagg tgagacttca
    20461 gctattatcg tttttaccct ctggggaaca gctgaaatgg gagacttggt acgtggagct
    20521 atcacttctc tccctaaaca tcagtttgaa agtggacagg cactcggctt gactaatgtt
    20581 caactttact accacatcat catcccacaa gtcttaagaa gactgctacc gcaggctatc
    20641 aatcttgtca ctcggatgat taaaaccact tcattagttg ttttgattgg ggttgtggaa
    20701 gtgaccaaag ttggacaaca aatcatcgat agcaatcgcc tgaccatccc aactgcttca
    20761 ttttggattt atggaaccat tctagtctta tatttcgcag tttgctaccc tatttccaaa
    20821 ctatccactc acttagaaaa acattggaga aactaaatgt ctgaaactat cttagaaatc
    20881 aaggaactaa aaaaatcctt cggagacaat cccatcctcc aaggactttc tctagaaatc
    20941 aaaaaaggga agttgttgtc atcctagggc cctctggttg tgggaaaagt accctccttc
    21001 gttgcctcaa cggcttagaa agtattcaag gtggagatat ttttctggat ggtcagtcta
    21061 tcgttgaaaa taaaaaagat tttcacctag ttcgccaaaa gattggcatg gtctttcaaa
    21121 gttatgaact ctttccccat ctggatgtct tacaaaacct catcctaggc cctatcaaaa
    21181 ctcaaggaag ggacaagaaa gaagtaacgg aagaagcttt gcaattacta gatcgtgtcg
    21241 gtttgctgga taaacaacat agctttgccc gtcaattatc tggtggacag aagcaacgtg
    21301 ttgcaattgt ccgtgccctc ctaatgcatc cagaaatcat cctttttgac gaggtgactg
    21361 cttcgctgga tccagaaatg gtgcgtgagg tgctggaact tatcaatgat ttggtccaag
    21421 aaggccgtac catgatttta gtaacccacg aaatgcagtt tgcccaagcc attgctgacc
    21481 ggattatctt cctcgaccaa gggaaaatcg ctgaagaagg aacagctcaa gccttcttta
    21541 ccaatccgca aaccaaacga gcccaggaat ttttaaacgt ctttgacttt agccaattcg
    21601 gctcatatct ataaaggaga ttcttatgaa actattcaaa ccactcttaa ctgttttagc
    21661 acttgccttt gcccttatct ttatcactgc ttgtagctca ggtggaaacg ctggtccatc
    21721 ctctggaaaa acaactgcca aagctcgcac tatcgatgaa aacaaaaaaa gcggtgaact
    21781 gcgaatcgcc gtgtttggag ataaaaaacc gtttggctac gttgacaatg atggttctta
    21841 ccaaggctac gatattgaac tagggaacca actagctcaa gaccttggtg tcaaggttaa
    21901 atacatttca gtcgatgctg ccaaccgtgc ggaatacttg atttcaaaca aggtagatat
    21961 tactcttgct aactttacag taactgacga acgtaagaaa caagttgatt ttgcccttcc
    22021 atatatgaaa gtttctctgg gtgtcgtatc acctaagact ggtctcatta cagacgtcaa
    22081 acaacttgaa ggtaaaacct taattgtcac aaaaggaacg actgctgaga cttattttga
    22141 aaagaatcat ccagaaatca aactccaaaa atacgaccaa tacagtgact cttaccaagc
    22201 tcttcttgac ggacgtggag atgccttttc aactgacaat acggaagttc tagcttgggc
    22261 gcttgaaaat aaaggatttg aagtaggaat tacttccctc ggtgatcccg ataccattgc
    22321 ggcagcagtt caaaaaggca accaagaatt gctagacttc atcaataaag atattgaaaa
    22381 attaggcaag gaaaacttct tccacaaggc ctatgaaaaa acacttcacc caacctacgg
    22441 tgacgctgct aaagcagatg acctggttgt tgaaggtgga aaagttgatt agtcattaac
    22501 tcttaaaagg aactggattt taagatccaa tcccttttta agatttcacc tataacatcc
    22561 tgagtctatc taagatgttc aatctgaaca cagtgtacat actttatctt ctattgcata
    22621 tactttatca cataagatac gaatatcctc ttcactatga ctagcaatca aaattgttgt
    22681 ccctttttca ctagagagct ttctaaacaa tgttctcata ttttctacac ttgatttatc
    22741 caaggcattc ataggttcat ctagtaaaag aatagaggga ttctccataa ttgcttgagc
    22801 aatccctagc tttttcctca tacctagcga ataagtttta actttctggt ctttttgctc
    22861 atatagacca actattttca gtgtatcatt gatttcctga ttaccaacta ctcctcgtat
    22921 gcttgccaaa tattgtaaat tcttaaagcc actataataa tttataaaac caggttcttc
    22981 aatcaaagct cccaaattag ctggaatttt tctctcagga acaatatttt ccccattgat
    23041 taacacttct ccataagacg gactatataa accagctatt aatttaaaca atacactttt
    23101 ccctgagcca ttcgcaccag taattcctat aatttccccc tgtttacaac taaagttaag
    23161 gttttgaaaa acacatgttt tttttaattc caactgaata ttttttaatg taattatttc
    23221 attcattcta taaacctcct cttttgacga gtgaaataga aaatgctttt aaaaagaaag
    23281 actaaaaata gcaactgaag aaataaatct cgtcctatat ctccattccc tcgatttaaa
    23341 atataaaata gataattagt tcgatttcct acaaatagac caccaaacac aatcatgagt
    23401 aaaaagaagc taacacaaga aaagttcatt tgctcattcg ctcctagtgc gtataacata
    23461 aagcaaaaca agactaacac acaagcattc aaagaatcaa ctataaacaa aactcctata
    23521 tcccagtttg gtaactgtaa cataaattga atcactagaa cttttaccat gattaaaatg
    23581 agtccataaa gaaaacaggt ccaaatctga tacctaatcc agagcttaat agaagaaaat
    23641 cgaatcactt ccataaagaa atcggatgct cttctacgat atacaattgc tagaaaaaat
    23701 gtatgaataa taaaccaatg aagcaaccat atagataaga ctaaaaaaga gttttgactc
    23761 agattaggcc cttttaaaat ttctataaca agtctatcat ttccttctaa ccaataccat
    23821 aatcctaaac aaatcaatat ccaaaaaaga acataacccc aaaagtactt ggtatagatt
    23881 atctgattca acctccacat gtgactactt aactttccca tttccaactt ttacactctc
    23941 ctccagtttc tatgaacaga aaatacagtc aatggaatta tgatagatag taatgtaagc
    24001 caataaatca atgcatacgg attggaattt accatatact gaaaaattgg caataatcca
    24061 attatcccat tgtccaactg ataaatccag aataaggatt ctacaaataa aaaagtaaac
    24121 agaaatacta agctcatgtt tgatttttta aaccaagaaa aactgctaat agtaagtaag
    24181 gataaaaaga aatagtatgc tatataagag aaaaaaaatc ctataaagaa actagcattg
    24241 tttgcaatac ttataccata aaattctctt aaaaaatcaa cctcctttat ctccaaagag
    24301 aagctaaaac cattactaaa tgcaatcaga aaaatcaata aaaataaagt cgccgtccaa
    24361 atccccgtac taagagctgc taatttgaaa ctaaaactgg taaagtgctt aattgatttc
    24421 agacgaatac gacactccaa cctattaaaa tagttattca tcaaataaaa aaagaataat
    24481 atatatgtga acggaaagca atatactcca gtcgtcatat cttgaagtaa aactaagatc
    24541 cattctaata catttggatg gattgaatat tggcgacagc gcaataaata tactgtacta
    24601 gataaaacac aggatagcag taatataaaa taaaccaata ctgataaaaa atcttttttg
    24661 taaaattgaa caaattgttt cattatacat agtcctctga atgtagaaaa aatgtaccat
    24721 aaacaaccaa acaactaaca aataaaataa aagcaagatg cccactaact aaggaaagac
    24781 tgatatcttt ctgatatccc aaagctaatg ttgtcacagg ttctaagtaa gatagcccta
    24841 aaatagccca aaaaatacca ccaaccatca tataggcaac tgggatgaaa atagctccta
    24901 tttttttctt cactagcaaa gcactagcta gtccaaaaat agagaacaca gcgccccaaa
    24961 ctccatacca gagagtcgtc acaagactat agagcaactg attagaatca aataattctt
    25021 ttaaggcacc actataatct ccaatataaa tttcctgata aggagtcact aaaagattaa
    25081 ttcctaataa taataaatag gggagaaaaa agactagaaa agaagaaata attgcagtac
    25141 tacctacaat agccagatac ttctttttag aaattcggca caattgtgct gttagaaaat
    25201 gactctcagc atcctctatt atctgactag aatagggcag tgtacagata agtgcagcta
    25261 ctaggctaat cggtgaaaat cctcgaatag aagaagcggc aaaaaaaatc gataaacctt
    25321 caattttata aataccattg aaagcaagga aatttcctaa actcatgcaa agaagggtca
    25381 aaaataaaga catataaaat cgaggtgatt gaacgactcg tacaagatta caaatgaaaa
    25441 attccatcct tactcctcct tataataaaa atagggtgta gcattctttt ttcatgctac
    25501 acccacaatc aaccatcttt aaggcttact ctgacaagta agttaataag aatctggact
    25561 ccaagaacct gaagtatgaa ttcttacatg atttccaaat tgtggcgcca tagctaatct
    25621 agtaccagaa ccaatataat tgtcaccacc tccattatag tacatgacaa tcctagagcc
    25681 agaccccaat gaatataccg gggtaatatc tgacccacta taggcgctac gaatagaggt
    25741 acttaacctt ttaccgccac cagtgctgtc actgttatta attccagcag aggcgttttc
    25801 tttctcaagc tcactagttg tatccgaacc ccaacgcggc aacgttaaat cataatttcc
    25861 aatctgtcta gctaaaactg tagggagaaa caaactagat gcaattgtaa ctacgcaaaa
    25921 aaggaatata tttttcttct tttcatgaca tcgtcctctt aagaagtgat aaacaagata
    25981 gttgattgat caatttgata catattacat tttcattata tcaataaaag aaagcgttgt
    26041 caattatttt atttaaaata ttgtcatatt ttaaataaaa tggtaaaaga gactcggtag
    26101 cctcgtctct ctttatctta ctgacctaac cttcttgcca attttcttgg tcttctttaa
    26161 agcgttttag aagatcaagg ccctctggcg tgatgtaacc ttcttcttgg gctagatgga
    26221 taagctcgct atagtttgaa agcgtcacaa gtttaacacc agcatctgca aagttcttat
    26281 ctgcttttgg caattggtag ctgaaaatcg ctacaactcc aagtacatct gctccttctc
    26341 gcttggctgc tgctacagct tcaagaactg aaccacccgt tgaaataagg tcttcaacca
    26401 ctaccatttt ttgaccttga gctacgcgac cttcgatttg attaccagct ccgtggtctt
    26461 ttggtttgct acggatgtag gcaaaaggca agtccatctt atcagcaata atggctccgt
    26521 gtggaatccc tgctgttgca gttcctgcaa tcacttctac ttcaggaaag gcttctttga
    26581 tagcttccac aaaaccattt tcaattaggg tacgagtttc tggataggct agtgtcacac
    26641 gattatcagt gtaaatcggt gacttgatac cagatgccca agtgaagggt tcctctggtt
    26701 tgaggtaaac ggcttggatt ttcaagaggt ggctagcgat atctttagca agtgtcatgg
    26761 tattctcctt ttatttttct aatctagttc tttaattcca gtcctgtgtc cattcatcct
    26821 tgatggcatg ataagctgca acaggatcct cagcttgggt aatgggacgt cccactacga
    26881 tatagtcact gccgatttga taggcatcag caggtgtcat gactcgtttt tgatctccaa
    26941 ctgcaacacc agctggacga atccctggtg tcagacagat aaaatctgga ttggtagcct
    27001 gcttgatgac ttgtacttcc tgagccgagc aaacaacacc atccaagcca gcttcagctg
    27061 tcttcttggc atagtgaatc acagactctt gcagactggt ttggatattt tgaaactcct
    27121 gcatctgagc ttctgacgtt gatgtcagct gagttacagc gatcaatttg gcttgactcc
    27181 caagaccttc acgcgccgcc ttcatcatct ctacaccacc agccgcatgg acattagtca
    27241 tatcgacacc aagctgagac aagaccttca tggctgactt gactgtatta ggaatgtcat
    27301 gaagtttgag atccaaaaag acactatgac ccaaaccttt taagtaggac acaatctcag
    27361 gccccgctgc gtaataaagc tccatcccta ccttgagata aaggctttct tctgctggga
    27421 aaagagctaa aaattccttg accgcctcaa aattaggaaa atcaagagca atgattggac
    27481 gatgttctcg cataggtttc tccttttgcc tttactagtg agagagtctg gccaacagaa
    27541 gccacgaaaa aaggaacctg ccaacagcaa ggttccacga aaaatgggta gtctccaccc
    27601 tttcaccgtc taaccttagc tgcctctctg gactgcttta aaggtttttt actattctat
    27661 tatttctact agcacttgtc aagtaaaaac atggtcacta aagaactata agagaaaagg
    27721 taaacctagc gacgcgatga acgctgattt gtttgatttc gattgctctc ttcctcttgt
    27781 tttttctgtt cttcttcctg ttttttctcg gcttccttgg cctcttgttt ggctttttcc
    27841 tcagcttcca taattaattt atccgccaca gtgtaactgt aaattccagc ttccatgtcg
    27901 accacactcg gttctgacaa ttgtggctta atcttactgt aatatggcag tttcttactc
    27961 atttcagata gaggaaccaa gacttcgtcc gaatcattca tggtcaatcg aattaaatcg
    28021 gatgtcacct tgcttggggc taattccacc ttttggatag ccgccttgag ttctgggcta
    28081 atttgagcaa gttctgagac aaaaaccttg atttgttcac tatcattaaa gagaactgat
    28141 aaataagttt ctggtaaact gttcagactc acagaactag tctcaagctg accactggaa
    28201 agaataggat aatgattttc accagaaata tagtaggcca caatatcata ttccttgacc
    28261 ttaatagtga acttagttgg aaattgatag acaagttgag ctgattcaac ccaatagtta
    28321 gacttaatct gcttttcata ttttgccttg tctagcagaa ggttaatcgt ataatccgaa
    28381 tcctgaatgc ctgaagcctg tcgaatatca tcagctgtag tttgcaccgt tccctcaaca
    28441 cgaatatctt tcatggtcgc ataaggactg agcaagtagg cagagacaat caataaaagc
    28501 agacttggaa ataaaatcgt gaaggctcgc aagatatgga taccaggaat ctttgctttg
    28561 gctggttttt cctttgtagc ctttttagaa agctttttat cctgttcctc cttctcttta
    28621 gactctggtt cttctttctc ttctttctct ttgtcagcct ctgaggatgc tactttttct
    28681 tcagactctt ccttagctga ttctgaatct tcctggtctg tttcactctc ctggtcctgt
    28741 ttgtcctctg acttctcaga ttcttctccc attcgagctt gtctttcctt ttccttctcc
    28801 tcagctagag ccgcctcttc ttcagccttc ttttttagat attcttggtt tcgtttctgc
    28861 cattctgata actctttcaa ttcttcgagg atttctttgt cctcattttt cttatctttt
    28921 gacatttact ttccttatga taaatctttt ttcaacaatt gataaaaatc tgctagagat
    28981 ttcaattcct tagaagcctt catcttagct tggtaatctt ccttgtgact tagtaagtga
    29041 gaaagcttct cttccaaact atccaaggtc aaatcgcttt cttgaaggtc ttctgcatag
    29101 ccttttttta caaagtaagc tgcattttca agctggtcac cacgactagc ttcacgacca
    29161 agcggcacaa tgacatgcaa ttttgctatc gccaagagct caaaaatcgt attggcacca
    29221 cctcgtgtca caacaatatc agccaattcc atcaagggtt gatagagatc ggtcacatag
    29281 tcaacacgaa aaagattttg gctcaactca ttcaggctag aatctccagt tagattgata
    29341 atattgtagc gctctgttag ttctttctta tggtctgtca ccaattggtt aaagacacga
    29401 gcacctgcag aaccgccaac aaacaataca gtcggcaatt tatgattaaa gtggctttga
    29461 atatccacca attcatctgg ttctggattt ttttgatctg aaaccttggt cactgctccc
    29521 acatgctcaa ccttagacaa actcgaagct tgctcaaagg ttgaatacat cttagtcgca
    29581 aatttatagg cgattttatt ggccaagccc atagacaggt cagattcgtg aataaagaca
    29641 ggcactcctg acacacgcgc agcgataaca ggcggtactg agacaaagcc cccctttgaa
    29701 aaaagggtct gtggacgaag tcgcaacatg ataaagagcg attggacgat tccccagcaa
    29761 actttgaaga cgtccagcat attttgccaa gagaaatagc gacgcagttt tccagtcgca
    29821 atagaatgga aggtgacatc caaacctgac ttaaggattt cttggtgttc gataccacgc
    29881 ttgtccccga tatagtggac ttcccaacca tcttcgatga acttgggcat taacaaaaga
    29941 ttgagggtaa cgtgtccaac cgtcccccca cctgtaaaga caattttttt catattattc
    30001 ttttaactcc gctactgtgt cgataaagag gtcgccacgt acttcaaagt tagcatacat
    30061 atcccagctg gcattggcag gactaagaag aaccacatct ccttgagtcg caagctcata
    30121 ggccttgcgg gtcgcatctg caatatctgt cgcctccaca taagcgacac cagccttgtc
    30181 tgctgcccgt ttgacacgtt ctgcagattg acccaggatg accatcttct tgagtccagt
    30241 aatgtctggc accaattcgt caaactcatt gccacggtcc aaaccacctg caatcaagac
    30301 gaccttgctg ttgtcaaatc ctgacaaggc tttttgagta gccaagatat tagttgattt
    30361 actgtcgtta tagaatttaa cacccttgat gtcatccaca aactggagac ggtgtttgac
    30421 accaccgaag gctgaaagag tttccttgat ggtttgattg tccacaccac gaagcttggc
    30481 tacagcaata gtcgcaaggg cattttccac attgtggcta cctggaacac cgatttcatt
    30541 cgctgccatg actacttcac cacggaagta gagttgacca tcttccagat aagctccatc
    30601 aaccttttca agtgttgaaa atggtacaac agtggcttct gtcttggaag tcaagtcttg
    30661 attaaagttc aagacaagga aatcagctgc tgtcatcttg ttctggatat tccacttggc
    30721 tgctacatat tccgaaaatg acccatggta gtcgatatga gttggcataa ggttggtaat
    30781 aaccgcaatc tctggatgaa attcttgaac acccatgagt tggaaagaag aaagttccat
    30841 aacaagcgtg tccttgtccg acgcagtttg ggccacttga ctagctggat agccgatatt
    30901 ccctgataaa agaccatgtt gcccagcagc agtcaaaact tccccaatca tagtcgttgt
    30961 ggttgtctta ccgttcgatc ctgtgatacc aataatcggt gcttctgaaa tcaaataagc
    31021 caattccacc tcagtcaaga ctggaattcc cttggccaaa gccttttcaa tcatgggatt
    31081 gttgtagggg atacctggat ttttcaccat aagagcaaac tcttcatcca agagttccaa
    31141 aggatggcca cctgtaatga ccttgatccc ttcttccagc aaactttggg cagctggatt
    31201 gtcctcgaaa ggtttcccat catttactgt cacaatggca cctagcttgt ccaacaaacg
    31261 agctgcagat tcaccagact tggccaaacc taaaacaagg actttcttat ttttaaattg
    31321 atctattact ttcatgtctc gaactccatt tctactccta ctattttacc atttttatgg
    31381 aaataaaaaa gccacaaagt gtgtttgtga ctctttcttc taactgaatc ttgccttatc
    31441 atctatgtga taaatcggta actcgaataa cttggtccac ttgttcccaa ataagaggat
    31501 tgtgggtcgc aataataata gttcgattcg gattttttaa agattctagg atggaaagta
    31561 attcctcaga gtttttggga tctaaggaag cggttggttc atctgcgagg atcaaaggtg
    31621 gatcctttaa aattatcttc gctagtgcaa cacgttgtgc ttctcctcct gataactcaa
    31681 atataggttg cttcaaatcc aaataagaga ggtttacacg gtttagagct tgtttcatca
    31741 aagagatttt ctctttttcc ttcaactttt taccaactaa acccagattg agattctctt
    31801 tgacggtttg gctttcaatt aagccaaaat cttgaaataa gtatcctaag taatctctaa
    31861 agaaaacaga aggcttgatg tccttaagag aagtgccatc atagatgatt tgccctttgt
    31921 catatggctc taatcgtcca atcatattca agagtgttgt cttaccacag ccacttgtac
    31981 cgattaaggc ataaattttc ccaccttcaa aatgaagatt cgtatctgaa aatagctgac
    32041 ggcttccaaa ttttttagat atattcttta gttcaatcat cctattttcc tttcataatt
    32101 gtcatagaaa cacgagattc tttctgcgct tgacggtaaa gcgtcagaac tgcactagct
    32161 agaaagacta ataaagtgag caagccaatc accaagtctc gactgcttaa aataaagaga
    32221 ctagcaccaa atacaaaact ggcaaattga ctaaccatat actgagcatg tgtttcaaaa
    32281 aatcgtaaac ctgaaattcg tttaatcaag atatctcggc ggaattgctc gaaatataga
    32341 agattgacag aataaaagag taacaaggaa ctagctatcc ccacaatagc tcctaagatt
    32401 aaagttgctg tttcagtttg aacttcatta taacgagtta gataaacact tcttccttct
    32461 ttaagatagg atacttgctc ataaattcca gctttcttca agagttctag cccactctca
    32521 tatcctttga taaagagttg ttttccagca ttgatagacc aactagataa ggatataaaa
    32581 ctatcacctg tagaagtcgg cgtgaataca actaaaatcg gatcaatcaa atactgagtg
    32641 gatacgggat tctcaccgtt attataaaca aaccgctttt ctcccattga aagataacta
    32701 acgtgcgctt tcatctcata atccaaagga gcacttgcct cctcaccaga ttttccataa
    32761 taactcaatc tttcttcaaa aactttctta agttctgctt ctcgagagcg caaatgttct
    32821 gggagcaaga ggataaactc acctttttgg agatgggcta acttctgttt ggtctcagca
    32881 tctaccacga ccttttcctt gtccaaataa ctgggactaa catagagcgt attagcatct
    32941 ggactatagg tatccagtgt ctctccctgt tcattttttc cttgtggatt ggcaaaatgg
    33001 agcagattat cctttacata aagagcttgt tcttcttcga ttgcttcctt ggcaaaggca
    33061 taccacttgc tctgattttc tgtatctttt cctctatcac ctaagccaaa agaaatttga
    33121 taatagtctg ctctatcctg ccatgcttgt tttgaaattt caagttcttt caatcgttgg
    33181 taagacatca aacctgtctt aacagcgtag cctactgtaa agacagcaac caactgacac
    33241 aatagggtta aagccatcaa gcgtttaagg ggtaatctcc ccttaataac aggaactaat
    33301 gctttgtaac tcaaactcat taggtaaagg agcattagta aaattgaaat cgccaataaa
    33361 aacaacagat agaaactaat cccaaaacca taggtggcta acaagatagg ataaaacaaa
    33421 ccttgactaa aaagaacgac tcccccacct aggaaggaaa ggagggctga tagaaggagc
    33481 catttgatat cagtagataa agaatgcccc atgatggata agagagtctg accagaaaag
    33541 agttttatac ctgctgctct catttcctta atccgagtga taatcactaa agcaaagaaa
    33601 gataagccaa atattgctaa actaattaaa ataaggggat ttagtaatat tcgaaaagca
    33661 agaaaatagg gcggtatctt tcggtcagca cttgctttat aacccaaatc tcctaattta
    33721 tcggcaagct tttctttcgt caaggagcct gacaaaagga gataactatt tagcggatca
    33781 ctacgttcac gactttcttg gctagcttct tggaattctt ttggtaaagt tccctgacca
    33841 taagttgcat aagtaaagtg agtcgtccca tccttactcg gctctacaat tcttctagct
    33901 attaaactct gttctgagtt tgcaaaattc tccaattcct gttcaaatac ctcacgcgtc
    33961 ggttcctgag tatctttttt gacacgaagt aaagaaacgg aatcatagct tgcatataaa
    34021 tattgtggcg cacgtaagac aataatccaa gcaaggaaga agctgagaaa aaaagttgat
    34081 aataatatga atagtttctt catagtagac tccttgtaaa caaaattccc cctgtaattt
    34141 cttacaaggg gaacgattta aatcaatgaa cgattagtca taatcacagt aaaatgctac
    34201 ttgttctccc catttagtcc aaatccatgc ataggaggtt tttccagcag gagcttctcc
    34261 tttatcagaa tgaccatccc atctgctcac gatggatgaa taatgatatt ttttaccatg
    34321 atagtaattt gaaaaagccc aaccacctcc tgaaccttct ccatatgtcc atactcctcc
    34381 atctggatat tgtacagcag ctgatgcagc tcccaataat gtaaaacttg aaataagaac
    34441 tagagcaagt aatctatgtt ttttcgtttt cattttattt tttctttcaa aaaaagcaca
    34501 ccttgagcaa caatgcaaca aaataaaccc tcctctttct tttgttgaaa ccgctttctt
    34561 atgtgatgag gataacattt ttattatttg ttgtcaagga aaaaatcgaa ttttttagat
    34621 attttactat attacctcta tgaataatat tatatagtag ttttatttca aaataatatg
    34681 caaccagtac taaccaaata taaaatagat gccattaaag aattttattc aagtttttcc
    34741 cattcatatt atccaaacaa aagagatggt gataactcaa aaataaattg caatcttgta
    34801 aaattcctag caaaaaagag agccgaaact ctctttttta tcttctttta ctttttttga
    34861 ctggcatgag tgtgatgtct ctcacactaa agtaagctag gatcaacatg gctattgcta
    34921 ggaatatttc tgttggtaat tgaaaaattt tcagaaaaga tagaaccaat aaaatcaaga
    34981 gtgccactaa aatacatacc atagcgacga tattgactgt ccctttaatg ctttctggtg
    35041 tcgcaaatac atagagtagg agcagtaaaa ttcctaggac taaatagacc atctttctct
    35101 ctttctagct cttattcagc tgattttttc ttcttgttag ctttctcacg ctctgctttg
    35161 ttaaggattt gtttacgcaa acggatagac tcaggcgtta cttccatgta ctcatcgtcg
    35221 ttcaagaact caagagactc ttcaagtgtc aagatacgag gcgtcttgat aacagctgtt
    35281 tggtccttag tagctgaacg aacgttggtc atttgttttg ccttcgtgat gttaactgtc
    35341 aagtcatttt cacgagagtt ttcaccgatg atcattcctt cataaacctc agtacctggg
    35401 ttgacaaaga tcgtaccacg ttcttcgata gacatgattg agtaagttgt agccttacca
    35461 gcatcgatag aaacaagggc accacggtga cgtccaccaa tttcccctgg aatcaatggc
    35521 aagtactggt cgaaggtatg gttcatgata ccgtaaccac gagtcattga caagaactca
    35581 gttgagtatc caatcaaacc acgcgctgga acaaggaaga ccaaacgagt ttgaccatta
    35641 ccagttgaaa tcatatccaa catttcacct ttacgttcag aaaggctttg gataacagac
    35701 ccttggtatt cttctggagt gtcgatttgt acacgttcaa atggttcaca tttaacaccg
    35761 tcgatttctt ttacgataac ttctggacga gatacttgaa gttcatagcc ctcacgacgc
    35821 attgtttcga taaggattga caagtgcaat tctccacgtc ctgaaacagt ccatttatct
    35881 ggtgaatcag ttgggtcaac acgaagggaa acgtctgttt gcaattctgc ctgcaagcgt
    35941 tcttccacct tacgagaagt tacccattta ccttctttac cagcaaatgg tgagttgttg
    36001 accaagaaag tcatttgaag agttggctca tcgatgtgta ggattggaag agcttctact
    36061 gcatctgtcg gagtgatggt ttcaccgaca aagatgtctt ccatacctga aacggcaatc
    36121 aagtcacccg ctttggcttc ttggatttca cgacgttcca aaccaaagaa accgaagagt
    36181 tttgtaacac ggaagttttt agttgtaccg tcaagtttag aaagggtaac ttggtcccca
    36241 accttaactg taccacggaa gacacgaccg ataccgatac gtccaacgaa gtcattgtag
    36301 tccaaaagtg acacttggaa ctgcaaaggc tcatctgagt tatctactgg agctgggata
    36361 tggtcgataa tcgtgtcaaa gattggtgcc atagtcgctt cttggtcagc tggatcatct
    36421 gacaatgaag aagttccgtt gatcgctgaa gcataaacca ctgggaaatc aagctggtcg
    36481 tcatctgcac caagctcgat gaaaagttcc aagacttcat ccactacttc tgctggacga
    36541 gctgatggct tatcgatttt gttaacaacc acgattggga caaggtcttg ttccaaggct
    36601 tttttcaata cgaaacgagt ttgtggcatg gttccttcat aggcatctac gaccaagaca
    36661 acaccgtcaa ccattttcat gatacgctca acttctccac caaagtccgc gtgtcctggt
    36721 gtgtccataa tgttgatacg agttccgttg taagcaacgg cagtattttt agcaaggatg
    36781 gtaatcccac gctctttttc gatatcgttt gagtccatag cacgctctgc caattcagta
    36841 cgtgcatcaa gcgtttctga ttgtttcaat aattcgtcaa ccagggttgt tttaccgtgg
    36901 tcaacgtggg cgataatcgc aatgttacgg atatcttctc ttaattttgt catgatttcc
    36961 tctataatat tcaaaattta ttttctaact gaacgattat accataattt caaataaata
    37021 acataactca agcaagtgta aatgttttca ctccgctttt cttttcacgt caagcctttt
    37081 caaagcaagc gacttatgat aagataggca cagtatgcgt ttagataatt tattagctca
    37141 agaaaaaatc agccgaaagg ccatgaaaca agccttactc aaaggggaca ttctcgtcga
    37201 tagttgccca gcccgctccc tagcccaaaa tatcgataca ggactacaag aactcctttt
    37261 tcaggatcga atcattcaag gctatgaaca cacctatctt atgcttcata aacctgctgg
    37321 tgtcgttaca gccaacaaag acaaggaact tccgaccgtc atggacctgc ttccatctga
    37381 cattcagtct gacaagctct atgccgtcgg ccgactggac cgagatacaa caggactcct
    37441 tctcttgacc gataacggtc ccttgggctt ccaactcctc catccccaat atcatgtcga
    37501 taagacttat caagttgagg ttaatggact tctaacacct gaccatatcc aagcctttca
    37561 aaagggaatt gtctttttag atggcactat ctgtaaacct gcaagactag agattctatc
    37621 agcaagtccc tccctcagtc aagcctctat caccatttca gaaggaaaat ttcatcaaat
    37681 caagaaaatg ttcctctcgg ttggtgttaa ggtgactagc ctcaaaagaa tccaatttgg
    37741 ggacttcaca ttgaacccag atttagcaga aggtaactac cgccctttga accaaaaaga
    37801 gttacaaatc attaaaaact atttagagat gagtcgataa aataaaaaaa gctttaaaac
    37861 taaagctttt ttcttttatt taccgaaaaa ttaaggcgat tgctacaatc cagttaacta
    37921 cagaaatcac aattcctaag atattaagaa tcttttctat tttatagtct aattgtgact
    37981 ctttttggta tgaaatagcc aagaccaatc ctatgatacc caaaatcagg cctacaattg
    38041 gaaataacaa accaagaata atcgacaaga tacccacaaa aagtggattt ttcttctttt
    38101 ctttcatgtt ctaagaactc tttaaatttt atacaaatta attatactat aaaacaatag
    38161 cttcatccta tcattcgact aatttggaaa taaggttagc tagtcttcac tttccctttc
    38221 caagaatcca agccataaga aaggatataa atctcagaaa aaccttgttt tttcaagtaa
    38281 agagctgcat ttgtaactcg ttgcgcacgt tggttttcgt agagaaggac aggtttatct
    38341 ttacgaagtg ctgcaagact agttttcaac tgacttgaag gaatattgcg tgcaccaagg
    38401 atatgttttc tgtggaattc tgctgggtcg cgcaaatcaa tcaattgacc cgtacgaatc
    38461 aaggcttcaa actccttatt gtccacaatt ttagccgcac ggcgaatacg aagatagtta
    38521 aagcccatcc acgccaacat tgctagtata agtgcccaca aaatccaagt aaccattagt
    38581 tcttttctcc atttttctca atataatcca attctacctt gtgctctctg cgaagaactg
    38641 cttctgcctc tagatagtct aatttatcca tcaaccctgc atcgtaaatc cgagatagtt
    38701 ccaacttcat cagttcaata tcatataagc gttttcccat gtaaacaata ataccaaatc
    38761 gtttgaggaa ttgctgcaca tcatagaatg ttttcataag actcattcta gcaaaatttt
    38821 gtgttttttt caagaagaga ctcatacaat gctccttatt ttcctatctt ctttagcgat
    38881 tctaaggcaa gtatggtaca ataaaaacat gagaattcaa caattacatt atattatcaa
    38941 aatcgtcgaa actggctcca tgaatgaggc agccaagcaa ctctttatca ctcagccaag
    39001 tctctccaat gcagtgcgag atttggaaaa tgaaatgggc attgagatct ttatccgcaa
    39061 tcccaaggga atcaccttga cccgtgatgg gatggagttt ctctcttatg cccgtcaggt
    39121 tgtcgagcag acccagcttc tggaggaacg ctataaaaat cctgtcgccc accgcgaact
    39181 ctttagcgtt tcgtctcaac actatgcctt tgtggtcaat gcctttgtct ctttgctcaa
    39241 gaaaagcgat atggagaaat acgaactctt ccttcgtgaa actcggactt gggagattat
    39301 cgacgacgtc aagaacttcc gcagtgaggt cggggtcctc ttcttaaaca gttacaaccg
    39361 tgatgtttta accaagatgc tggatgacaa tcacctgcta gcccaccatc tcttcacagc
    39421 gcaaccgcat atctttgtca gcaagaccaa ccctctggca aagaaagaca aggtgaaact
    39481 gtctgatttg gagaatttcc cttacctcag ctatgaccaa gggacgcaca actccttcta
    39541 cttttcagaa gagattcttt ctcaggaaca ccacaagaaa tccattgtgg tcagtgaccg
    39601 tgccaccctc tttaatctct tgattggttt ggatggttat accattgcga cagggatttt
    39661 gaacagcaac ctaaacggag acaatatcgt ttctatccca ctggatattg atgacccgat
    39721 tgagctggtc tatatccagc atgagaaaac cagcctatct aagatgggcg aacgctttat
    39781 cgactatcta ctagaagaag ttcagtttga tagttgagaa atgataagaa ccaatatgta
    39841 ggctagcaac aacctgcaca ttggttcttt ttacttataa ttaaaagttt cccctgccaa
    39901 cttatcagct agcttgggaa agagagtata aaacttatgg gctaggttca acaaaatcgg
    39961 gagattgagt tctcgtttat ttttgcctat aatcttgaca atctttttag ccactgcatc
    40021 tgcctctaag aggaagcggt caaccgattt aagataagtt ccatctgggt cagcttggtc
    40081 aaaaaatcct gttcggattg gacctggatt gactgttgtc acatagactc catagggcat
    40141 aagttcgagt cgcagagcat ttgaaaaacc aatagccgca aacttggtcg ctgagtaaag
    40201 actagacttg ccagtagcta ttagacctgc catgctgacg atgttgatga tatgcccttt
    40261 gctgctttcc ttcatacgag ccgcaaggtg acgagacaga ttcatcaggg caaaggtatt
    40321 gacctcaaac atctggtgaa tatctttatc agcaatctgg tcaaatccct caaaaatccc
    40381 gtaaccagcg ttgttaatca agacatcaat cttgccatag cggagataaa gatcagttac
    40441 cagagcttct agggctgaat cgtcggtaat atcaatttca atcaattctg catgggaata
    40501 atttccgtag agttgggcta atttttcctt atttctacca agcaagatga gttggtcatt
    40561 gggcaagagt ttgaccattt cttgagctag accaccgcta gctccggtaa tgagaatagt
    40621 aggcatactt atcctttctg tgactgctag atttccactt cttccaagtc tttgaccaca
    40681 tggacatttt caaaaattgt ggcagcgtcc ttcttgagtt tgcttatatc ttttgagagg
    40741 aaacgggcac tgatatggtt gagtaggagg cgtttggcac ctgcttctac cgctacttgt
    40801 gcagcttgca tattagttga gtgaccatgg ttacgagcaa ttttttcatc acccttgcca
    40861 taagtggact catgaactag gacatctgca ttgacagcca gacgcacact ggcatccgtt
    40921 tttcgagtgt ctcctaaaat agtgataatc ttacctggac gtggcgctga gatatagtct
    40981 gctgccttga tttcagttcc gtcttccaaa acaagatcct ggccgttttt gattttacca
    41041 aaaagcgggc cgaacggaac accagcagcc ttgagttttt cagcatccag cgtcccttct
    41101 agatcctttt gcatgacacg atagccaaca cagaaaatag tgtggtccag ctcctctgca
    41161 tacacagtga atttatcggt ttcaagaatt ttacccagag aatcttggtc aaactcatgg
    41221 aaatgaatgc ggtagggcag acgagaacct gacacacgaa ggctggttaa gacaaatgac
    41281 ttgattcctt gaggtccgta gatttccaaa tctgtctgct cttcattggc ctgaaaggca
    41341 cggctagaaa ggaaacctgg caaaccaaaa atgtggtctc catgcagatg ggtaataaag
    41401 attttgctga ccttacgtgg tcgaattgtg gtttccagaa tgcgattttg cgtaccttct
    41461 ccacagtcaa agagccaaac ttcgttaatc tcgtccaaaa gtttcagggc gagacttgaa
    41521 acgttgcggg ctttagaggg ctgaccagcc cccgttccta aaaattgaat atccattcga
    41581 tactttctaa ttaatcaata tataacatgg ctgtgcggtt ttccgatcgg aaatagcgtt
    41641 tgccagaaaa agcagcagct tcttgcaata aatcctcttg gctgtagcct ttgagacgtt
    41701 ttcgaccatc agccaatctt tccaaatcag tcaaagctgt gagactttct aggctgacaa
    41761 cttcctcgtc cttgacaggc ttcatgtaaa tcttaccaga ctcttcaaag actaattgat
    41821 gggagaaaat ttgcgcaatt tcaaagagca agtcatccga gattttctcc tcattttcag
    41881 agaaaatccg accaaagccg tcactctcat aacaaaaacc aaaggattta ccagacagat
    41941 taagccgaat aaaaggctta ttttctaggg tgaaacttgg ctcagtattg taaagattca
    42001 gttcctgact gagttctgca aaataatccg tcgcagcctg aggacttttt ttctgataga
    42061 gttctgcaaa gtaggcatta acaacacttg gcggaggtgt aataagtgtt aactgctcct
    42121 gctctgtttt accagctaga agctgatcca gatagacctt gtccagactt gtataacctc
    42181 catactttag agccaaagtt ttaatatcag tcataaaatt cttctaacct ccatttattt
    42241 ttctcggaaa tgtagcctgt aatcacttcg ccgtcttcct gataatcacg ttcttccaga
    42301 attgcaacac tctctaaatc atgaatcttg taggactttg aaaaaggcac tcgcagggta
    42361 aatgcttcaa aaatttcctt aatcttatct agcaataatg cttgcaagtt ttcacgactg
    42421 tcctcagact tggcagaaat gagggtatat ggcgtttggg taggcgtgaa atcctccacc
    42481 aaatccgctt tattataaag cgtcaagtga ggaatatctt ccatgtccag gtctttcatg
    42541 atggagagaa ccgttttttc atgctcctcg tggtaaggat tgctagcatc gataacatga
    42601 accagaaggt ccacatgctt gctttcttcc aaggttgact tgaaactgga caccaactct
    42661 gtcggcaaat cttgaataaa gccaacggta tctgtcaaag ttacttggag attgcctccc
    42721 agatgaatac tcttggttgt cgcatccaga gtcgcaaaga gctcatctgc ttcatactgg
    42781 gtcttactgg tcaagatgtt catgatagtt gatttcccag cattggtata accaatcaaa
    42841 ccaatcttaa aggtgctaga ctccaaacgt ttttctctga cagtcgcccg atttttctca
    42901 accaccttga gctggcgctc gatatccgtg atttgattgc gaacgctacg acggttcagc
    42961 tccagctggc tttcaccagg accacgggaa ccaattcccc ctgcctgacg gctgagcata
    43021 atcccctgac caaccaagcg aggcaagagg tatttgagtt gggctaggtg gacttggagc
    43081 ttcccttcat ggcttcgagc ccgcatggca aagatatcca aaatcaactg catacggtca
    43141 atgaccttaa caccgagaac ttcctctaga ttgacattct gccttggggt cagacggttg
    43201 ttgacgatga cagtagtgat ttcttctgca tccaccataa gcgcaatctc ttccaactta
    43261 ccagagccga cgaaggtctt ggaatcatat ttttcacgtt tttgtctgta gctatctaca
    43321 acgactgccc ctgccgtttt cgctaaacta gccaattctt ccatggagag gtcaaaactg
    43381 tccataccct gcaattccac accaatcagc aggactcgct cctctttttt ctccgtttca
    43441 atcatctaaa aactccttta tctggcttaa aatgcggtct tgtacaccag attctccaat
    43501 ctgataaaag gtgacctgca tgcgattacg gaaccaggtc agctgacgct tggcaaaacg
    43561 acgggtcgcc tgtttaagac tctcacgagc ttcctcaaag gtctgctctc cacggaaata
    43621 aggaaagagt tccttatagc caattccttt agcagcctgt acattagggg aatggtcaaa
    43681 cagccacttg gcctcatcca aaagcccagc ctcaaacatc aaatccactc ggtggttgat
    43741 acgctcataa agttgactac gttcatcatc caagcagata atcagcggtt catacaagat
    43801 ctcttgattt tccaaatcct gaccaaaatg ggcaatttct aaggcacgca tagcacgacg
    43861 acgattaaac tggggaatct caaggcctgc ttgctccacc aaatgggcta attcctcatc
    43921 tgaatatggc tccaaactag ctcgataagc taaaatctcc tcatgaggag tctccccacc
    43981 taggtggtaa ccttctagca agctctggat ataaagtcca gtcccaccgg cgataatggc
    44041 tagcttgcca cggctgtgaa tatcctcaat agtcatctta gcttctgaaa caaaatcaaa
    44101 agccgagtaa gactcggtta tctctctaac atcgattaaa tgatgaggaa cagctgcctg
    44161 ctcttctgga ctagccttgg ccgtcccaat atcaagtcct cgatagactt gctggctatc
    44221 tccactaacc acttcgccat taaagcgctt tgcaacttca atagctagag ccgtctttcc
    44281 aacagcagtc ggtccaacaa tcacaattat ttttgttttc atcttttttc cttgaaaaat
    44341 tcccattttt tcgttactat tattataaca caaaaaggtc agtcagaaaa atgtgacctc
    44401 ttgaggaggc tggctgattg agaatataaa ggaggaagac tcatggctaa aggattcgct
    44461 aaaggtcttg taacaggtgt cgcaggaact gtcgctgccg ttgcaggtgc agtatacgca
    44521 tttaaaaaga aagtaatcga accagaagag caaaaagcag ctttcatcga agaaaatcgt
    44581 aaaaaagcag ctcgtcgccg cgtatcacgt taagaaacaa aagaagttgg gattattctc
    44641 aacttctttt ttctattctt ttaaatagct aggtcaaact tcaactgtgg cttaacaggg
    44701 tcataatcca ccaactcaaa atcttctgct ttgatatcaa agaaattagt cccatcagga
    44761 acatttaaaa ccaagcgtgg ttggcagttt gacggctccc gacggagcaa ttcctgagct
    44821 tgttcaaatt gattatcata gatatggagg ttgttgatga aatagaagaa cttcccaacc
    44881 ttccagccaa aatgtttggc aatcatcatc tgcaaagcca catactgcat agcgttgatg
    44941 tggtgggcca ccagcatatc attggagcgc tgggtcaagg tcgcatccag atagatttcc
    45001 ccatcaacac gccggacatc aaacatggtc tgaaaggcgc acgggagcag cccatctgtt
    45061 tcttcgaaag cttggtaatc ccagagcgaa ataatattgc ggcgattcca aggattggtt
    45121 tccaactgtt tgagaagctt attgataatg tcgtgtttct taacaacggc accatagcgc
    45181 tcaccaatgg ttcccgtgtc tccaacttcc cagtcattcc agtagtgaac attgtacttg
    45241 tcattaagca cttctaagct atttgactgg tcttgataaa tccagagaac ttctttgatg
    45301 gcggatttga ttgcaatggg acgcaaggtt gtgataggaa attctccttt agataagtcg
    45361 tactcggaaa aggcaccagt tacatacttg gaattagcaa cagtcccatc cttgtactta
    45421 ggacgagctt gctctgagaa aacaccttcc tttagaatgc attcaatatt ctctttaaaa
    45481 atcgtatctg cttttgtcat ttactctcac ctcattcatt gtcctaacta gtatagcata
    45541 aaaaataaaa gaggaacatt actaactcta ggttagcatt ttcctctctc attatcttat
    45601 tgcaatacaa gtgatgctgc tccgataact ccagcgtcat ttcctagagt tgcaagagct
    45661 aatttagtag atgtgcgtac ttgtgggaaa ctattttcat cgtaaacttt ttgaacacct
    45721 tgtagaagga attctcccgc agctgacaca ccaccaccga tgacgattgt tgatgggttt
    45781 aggattgaac caatgttagc acaagcgatt cccaagtaac gtgagaagtt acggtaaaca
    45841 atcaaagcaa ggtcgtctcc ttcttttgcg agatcaaaga cagtcttagc agttacttct
    45901 tctccattat caatcaagcg tttcaaggct gcatcgcctt cgtattcatc ggcatagcga
    45961 cgagtcaagt tgacaatccc tgttgctgaa gcaactgtct caaggcagcc tttcttaccg
    46021 caagtacatg agattggctg gtcaaagtca acagtgatgt gaccaagctc acctgctgca
    46081 ccagcaacac cgtgaagcaa tttgccttct gcgacgatac cgccaccaac accagtaccg
    46141 agtgtcataa agacaacgtc tggttggtta tctccagcac ccatccagcg ctcaccaaga
    46201 gctgctacgt tggcatcatt atcgatgaaa aatggaatgc ccaaagcttt ttcaatcttt
    46261 tgtttgattg gttgaagggt tttccagttc aagttgtagg caccgataac agtccctttg
    46321 tcacggtcaa ccacacctgg tgatcccatt ccaatgcctt ggaagtccgc tgctgccaat
    46381 ccaagcaagt ccaaacgatg ttgaatagac tcaatcatat catcaacgat atgacttccc
    46441 tcatccaaaa tgttggtctt gattgaccat tttccttgga tttctcctgc tgttgttaag
    46501 attgcaaatt tgatagaagt tccaccaagg tcaatcccaa taatcttttg actcatcata
    46561 ttctcctttt tcattgtgta gtaattgaaa atgcttacag tactagtata tcaaaatcca
    46621 ttcacttatg caaaggtttg cgtaaatgaa ttataaggaa ttttttcgcc taccagtatc
    46681 tgttaatcat ctaatgatca atggcatatt gagctgcatc atttgaaaat ttatcaaaat
    46741 cagaagttaa ttgtctatac atacgttttt tttgacatgt ggaataacga attataactt
    46801 tttgcctttc ctaaagcagc agaatattca ctattgctat cattactaga agaagctgta
    46861 cttgcttgac cttccttcca aactccgtca gcgccaacat aataacgtcc accatcaacc
    46921 cattcattga cagccatttt accatccgat tttagatagt aatttccttg ccatgtactg
    46981 taagcataag aaccatctga tgtcaaataa taccatgctt gataggtggc atcataaacc
    47041 cattcattga cagccatttt accatctgat ttcaaatagt agtttccttg ccatgcattg
    47101 cgagcatatg aaccatctga tttcaagtaa taccatgctt ggtaagaaga atcataaacc
    47161 cactcacctt gtaccatttt accgtttgat ttaaggtaat aagctccttg ccatgcattt
    47221 tttgcataag aaccatctga tttcaaataa taccaagctt gataagaaga gtcataaatc
    47281 cattcactct gtgccatttt accatcagct ttcaggtaat agcttccctg ccatgcattt
    47341 ttcactagat ttccatttcc atcaaagtag taccaagcgc cgtcctgctt aacccaacca
    47401 cttgttgttg ctgaacttgt gttgatttga atagccgttg actgttttgc tttaaaagca
    47461 cccttaggag catttttcaa ttcgcaagcc acaccatcat gatcacggtc taacttggca
    47521 gaataaccag gttctccctc gtaaatatcc gaatagccat tcgcccaagc ttccttacag
    47581 ctcgaaaaat ggatgttttc ttccgccaaa actggttgtg aaaacaaggc taaaattggc
    47641 aacgtcacca gactcatttt taaaaataga cgtttattca tttctttctc ccataattat
    47701 gatatcgatt tcaatattat tttatcaaac ttatttcagc aattcaagga aacttctggt
    47761 cttttctaca aactcctttg gttttgcctt attcaagaca tgagggccat caggaatgat
    47821 ctgaaactgc gaatctgtta acagtctatg gagagctttc atagaactaa gattcggttt
    47881 atctttgctg ccacaaatta gtaaggttgg ataggagcaa gtccctgcta tatccgttaa
    47941 atcaagtgtc ttcaattcct cagaaactcc gaccataaga gtcttgtctg ctccctgttt
    48001 ttcaaatact cttttgggaa gtagtttaaa aatcagcaat tgaagataaa ataggatatt
    48061 ccctgctaat ttaagcgggc atcctgacag aatcaaagct cgaagatttg gtaaatcgta
    48121 actggaaagt tctagtgtca gggtagcacc taaggacaat ccaatcaaaa caaaaggttc
    48181 tgtctcttga gctaggtgct gataaactcg ctctttagct tgttgatagt tactaactcc
    48241 agaaggaaat aactcgatag cctcagaagg ataatctgtc agtagattcc gaacttcttt
    48301 ccaagactct gctgactgcc ctaacccatg caaaaatatc aatttcatct agttctcctc
    48361 aaggcttagt tcatacaagc ctctcactgc attacagccg taaatagctt ctgcttgggt
    48421 taaatctgcc aaggtcaaga ctttctcttc tacctgtcct gtttctagca aatgctgacg
    48481 gtaaattcct ggcaagattc caagtcggat aggcggtgtg tagagttttc cagcgatttt
    48541 cagaaccaaa tttcctatag aggtttcaag cagttctcct gacttattgt ggtaaatctt
    48601 ctcttgttct cctaggctca aatgcggtcg gtgagtggtt ttaaagtagg taaaggattg
    48661 attcaaagca gcttcctgaa gacagacttg ggcctgacaa aagcttgtac tgagaggggt
    48721 taatacttga cgattgactt ctatctctcc agatttgcta aggctgattc gcaagcggta
    48781 atcttgatta gcttcacaat cctgacactc ttcctcaatc ttgtgtccca agtcttctgc
    48841 atcaaaagga aaggcaaaat aacgactggc ttttctcagt ctttccagat gttgatcttc
    48901 aaacagcagg ttcttctggc tgatttcccc tgtcgtaatc agttggaagc gagcttgttt
    48961 acgataaaga actgctgcct tttgatgaac ctctcggtat tcagattccc atgtgctatc
    49021 ccaagtaatc cctccgccaa ctccataaat tgcttgacct ttgtgaagtt gaatggtacg
    49081 aatggccaca ttaaaaatcc gtcgtccatt tggaagcaag agaccaatcg ttccacagta
    49141 gactccacgc ggttgaggct ccaagtcctt gataatctcc attgtcgcaa ttttcggtgc
    49201 acccgttatg gaaccacaag gaaagagtga gcggaagatt tcaacaaggt ccacatcctc
    49261 tcgcaactga ctcttgatgg tcgaagtcat ctgccaaaca gttgaatact gctctacctg
    49321 acacagacgc tccacgtgct cgctcccaac ttcagaaata cggttcatat cattgcgcaa
    49381 gaggtccaca atcatcatat tttcagagcg atttttggga tcctgtccca accaactggc
    49441 ctgttcaaga tcttcttggt cagttacccc acgctgagtc gtccccttca ttggtcgtgt
    49501 tgtcaactcg cgatcatttt gctcaaaaaa gagctctggg ctcatggaaa tcactgccat
    49561 ctcgtcatgt tccacatagg cattgtagcc cgcctcctgc tctaccacca tacgattgta
    49621 gatggcaaaa ggattggcac ttaacttttg cttgagttgg acggtgtagt tgacctgata
    49681 ggtgtctccc tgcctcaagt gatggtgtat ctgggcaatg gccttttcat agttctctgc
    49741 agacgttact tcctgccaat ttgagggcaa atcaatatcc tcataagtca gaggaatagg
    49801 ggaggtctcc accctatcgt gaacagtaaa gtaaagcaag tactcgccca gtagaggaac
    49861 cttgtgaact gctaatttct cctcaaaagc aggtgcagcc tcgtagctga cataccccac
    49921 cacataataa tcttgctctt ggtagctttc cacttgtgcc agcaaatctg ccacttctgc
    49981 tacatttctc gttttcaact ctttaatagg ctgggtaaag gtatatctct cccctaaagt
    50041 cctaaaatca atcactgttt ttctatgcat accttaagta tagcataaaa aggcagatac
    50101 agacaaagct gatctacctt tttccgattt tattcattct atgcttgtgg tgcagtaaat
    50161 agatcaccag agaaaccgtc tgtgttttta aggagttgtt tgtatacttt ttctttaagt
    50221 ttcacagtct tatccgttcc agttccttta agatcttctt caacagcttt atcaaataag
    50281 tcttttaatt tttcatatga atcaatagtt ttaccatcaa tttcaattgc tgtgaatcct
    50341 ttttgagctt tagttttgat ttgtttaaac cattctttct tccacgcttc aagtgtatta
    50401 aatgtaccac cagaaacttt attgatgata tatttatcac ttagagtttg acctgcttta
    50461 ttggcttcgg ctttatattt attagaggca tatccgatga atccattttc gtatccgaag
    50521 tatccccaca tacggaaagt attatgttta aatgaagcag cgccaggagc cccatcactt
    50581 gagttacctc cgtatacacc agtcatcata ttcatattaa catatgctga actaaaatct
    50641 gatgggttat atgtaccatt tccaggagca ccgtgtttag tcataaagtt attatcaact
    50701 aaatcctcaa tagaagctaa ttgaattttc ttctcttcat tatttaaatc gcgaattttg
    50761 tcaaactggt gaggttgtcc gtccttacgc atttgtttat ccattttctt gaaccatcta
    50821 tcattgttac cttttaattt aggtaaaaca gattctgctt ccagataatc taacatcata
    50881 agagcttcat tgtagttctt catgtagtga tcaatttcag cgcgagattt aagtttgtta
    50941 ggatttggat tataccattg atttccatca ttttgacgtt catacgccat atttagacct
    51001 aatgcgccat attctccgtt tggatttgat accgatggcg tttgtaacat cccctgagca
    51061 aatgcttcaa gatccgtacc ttcacgatgc caatgaccac catagtaagc catacgatca
    51121 ttaatgtgag tagtttcatg tgtaaatgca gatgttccaa agtcactaat taaatctgtc
    51181 ataacgaaat aaactgcatc catcggttga ggtgctgcaa aaatatatgc atatgcgcca
    51241 tatccatatt tgtaaccatg atacttattg attcgcccaa agaactcacg aattggagca
    51301 taatccggtt tcccatctat atgaccatgt ctactagccc atccgttcgg gctattatga
    51361 ttatcccata caggagttgg aactacattt tgactcttaa gaagtttatc acggacatta
    51421 tcagtagcaa gacgtgacca aaaatctaag taattaacct gctctttagc acgtttattg
    51481 atctcactct taaacttttc acgtttttca tctgtgtctt tgccatattt ttcaaacgaa
    51541 ctaaacgaga tagtgttgta tgttgaaatc ataaatagat gtgcattttt caagttaaga
    51601 agaggtaaaa tcatccgccc atgttgccca ttattaattc cttcgtatag acgatatttt
    51661 ttgttggcaa atgcagggtt cgttgatggt tgttcaacta cataagcatt cttttcaata
    51721 gctttcttaa accagtcatt tatatctata tggttagtaa atagcttcat attgtaatgt
    51781 aagaatccat ttaattcatt tattccaatt gttccaccga tagtttcacg ataagcttct
    51841 aaagttctat cacctttaac atttctttca cttgaaccaa ttttgattaa gaaatctaag
    51901 acattaacat tcttaccata aaaatcaggt ttaaacatca taatatcttt aattgataac
    51961 tcagcgtatt taaaactata atattgattt aagtaggtca gtcccatcat gattttagct
    52021 ttattgtctt caactttctt aattaacgcg cgcattgctg cttcatcgct atttaattga
    52081 taatcttcgt tttcaaccaa agctttaacc aatttaccca aaccagcttt cacttcagca
    52141 aagctttctt caaggaatag atctctaatg tatccatttt gacgaccttc cgtattttct
    52201 tcagctttac cacgtttatc cataagagca cgaacttcag gggaaatcaa ttcaactgac
    52261 gacaatttcg ctttcacatc tgcaatcaat tggtcgcggt ttttatcaac catattcgga
    52321 gtgtaaacaa cacccaaatc agtcacgtca tactcacgaa cttgtttcac cttagaatca
    52381 gcaaccgctg tcacgttcat ttcttctttg gtgccatccg catagtgaat cataatttta
    52441 tcaatttctg ataagtcagt cacaaattga ccatctttca tacctgtaac agataatact
    52501 tctgtagtta ataatttaga atttgatgga actttattac cttggtctac aatccactct
    52561 ttattgtaga atggttgaag tttttcgata ttacgataag caagttcacg gtctgctttg
    52621 taatcttgtg ttgttctata ctcattatca cgtgttgtga gagcgttgag tttatttaca
    52681 attggctctg taattgcata tttatctgct gtgatagcca attctttaat tttcttatca
    52741 gcttcctctt gagatactga tttaatgcga ttttgttgtt tagagtattt atacgaagat
    52801 ttaccttcac ttacaccgtc aacaatgaaa tttctattta ctcgttctcc tgtgtaatat
    52861 ggatcggtat cgatatcatg cgaaccgtag aaaatttcac cgttcttaac tttcatcata
    52921 gcaacagtgt cttctatata accaagataa tttaaacttc caacagcgcc accaacttca
    52981 attggttttt ctacatctat tgaaccttta acgacagatt tcttaattgc tccatatcta
    53041 cctacagcat agttatcgcc tccattttgc gaccagtaag ctatacctgc agccttagct
    53101 ttcttccctc gaatattggc atctacataa gcctgttcta ccagtccctt ccagttttca
    53161 ccaacaatac cagtcaagaa cgaaccacct gtaccaacag aggtcacatt cccaataaaa
    53221 gctacatttc tcaatgtacc gccactatct attttatcta taaatccaga tacccagtct
    53281 ttaccaagaa cattacctgt aactttgaca ttttcaatag tggttccacc tttaataata
    53341 ttagctaacg atgcaacgtt atttgcccat ggcatgtgaa tattaacatt gccaaggtta
    53401 atatctttga tagtcccacc tataatatta ttaaacaatg ggcgacttgt attatgaatt
    53461 gtgtaatgtt caccatcaac acttgtcaaa gtacctcgga aatcacctgt aacatacgac
    53521 ttagcaggtg tcggtacacc tgtagcgttc aaatcagcac caagtttgaa tgtaccagtt
    53581 ttgtttttgt tcatggcgtt tactaagtcg ttaaagttgt agtaaatatc accatctgtt
    53641 gcacgtgttt tttcaatata atacacgtat tcgtcttgca ttttagtcgc atccgtgtgc
    53701 tgaatcaaat taggagcctt agcagtgact ttgtaaagtg gttgaccttc ctcagtcacc
    53761 tcttcaattt tttcaactgt gaggcgaaac actttattat cacgtgaagt tactttgagg
    53821 tagtaattct gcacatccac aggtttactt gttaagaagt cacttgccac ctcagtacca
    53881 tcctcattta ctttgacgag attagtagag ccgatgtttt tcaattcaac cttcttgagg
    53941 tctaatcgta gtggagtttc ttccaacgta gaggtttctt caccattacc tctatcatag
    54001 gtcatactcg tcacaatctt ataatcttta taaagttcaa gaccgtcaac agcatctgat
    54061 aatctctctt tagataagtc aatagttttg acaaccttat cgccattttt aatttcagca
    54121 tgaatttttt tcacatcaac actatctgta ttttccaaat gataagtaag tctcgcacta
    54181 cgcaacattg cattatctgt aacacttgtc aaacttaaga ctggagctaa tttttctttg
    54241 ggtttcgtgc caacacgaac aacctctttc tccatctcag cttcatcagt tgtcgaagtg
    54301 ccttctgtag tcgtaccatc tgtcgcattc aagatatatg gagtagtaac tgttctactg
    54361 ccattcttac cttccttaac aacttcacgc gttccgtgtt ccttagtaag gtcttcctca
    54421 tagcgagtag tttggggaat acttgttact tcaacttttg gttcctctgt tggttccgtt
    54481 tgtttttcta cagcaggcgt ttccactttt ggttgttcaa caggttgatt aacagtctcc
    54541 tcttttgatt ctactggttc ttcaaccttg atttctgggg cttctgctgg ctgttcatct
    54601 tcttgtttcg gtgtctcttc cgctccccta tcttctttag gattttcttg ttgtgatgat
    54661 tcttttggtg tacttggttg ctcagcttgt gtaggttgca cgggttgttc tgggactttt
    54721 gcttgttcta ctggtggttc aacttttgat tcctcagctg gtttgtctga tggttgactt
    54781 tctggcttaa ctgctacttt ttcctctggt tttgactcaa cttctccacc tacttcttca
    54841 actggagatg gttctgctga atcttctttc ccctcttcta ctttaggaag ggtgtcgtca
    54901 gtaggtttta cctccgattt tggttcttcc tttggacttt cttctgtttt aggtgcttct
    54961 tcttttggag cttcctctgt ctctactact tggttttctg tcctagcttg ctcctgattt
    55021 gttgttgatt gaggagtctc aacttcgact acagtcacct ctccaggttt tgctgaggtt
    55081 tcttctaaaa cagtgtccaa gccaagcgtt ttgaggatgt cacctgatag ataaccaaca
    55141 tagcgatagc catccatttc aacaacaccc tctcgactag ccagcgctag ggtcgcaact
    55201 gggtctacag cccctgcact aggaagaact accaatccca tagctccaac tagaaagacg
    55261 ctagcaattt tctttctctt gtagattaaa agcaagctcc caacagtcag caaaccaaaa
    55321 gctgtcaaaa cagatgcttc tgtccctgtt tgaggcaact gatctttttg atacaccaaa
    55381 ccatatacaa cttcattcct gtcaggcttt cctgtctgaa ttaaatcttt agcttcttgt
    55441 gaaataatct ctttatttac atagtgatag gtggctgcgt ccactacaga aggagccatc
    55501 aaaaggcttc caagaaatac agagcctaca actcccttaa tcttacgaat tgaaaaacgg
    55561 tcttttttaa acacttttat ctcctttatt cattctcaag actttctaat agcgtcttgc
    55621 ggatagtgcg cacgcgcacc tccgattaat tttggacgac tagccagtgc cgttacatgg
    55681 gcatgaccaa tctctctcaa aatagggcga atcggaacct gaacatgctt gacatgcatg
    55741 ccaattgcag tgtctccgat atccaatcca gcatgagcct tgataaattc aacctcaact
    55801 ggatcctgca taaacttaaa ggctgccaac tgccccgaac ctcctgcatg aagagtagga
    55861 tggacactga caatttccag atcaaactgc tctgccacct gacgttcaac aacgagagcc
    55921 cgattgacat gctcacaacc ttgaactgct aaatggatac ctctactacc tagaataccc
    55981 aagatagtct ccactatcag ctcaccaatc tcttgactgg attctttccc aatctgacca
    56041 cctagcacct cactagaaga tagacctaaa acaaaaagga ccccctgctt caaattggtc
    56101 ttttctaaaa catcttccac tacctgacgt gtttctcttt gaatctgtgt ctcgttcatc
    56161 tctgttacct ctgttgtcac tcttctatca taccgttttt tcttgttttt agcaagatag
    56221 acaacctata aagtttgccc aattacgcat aaaactccca gaattaactg ggagttagct
    56281 agtttctact ctatttatat atatttcaac tttcgtccct ttttggggtc tagaatcaat
    56341 cttcatctgg taattggctc caaaatgaag tttgagccgt tgatcgacat tttgaagacc
    56401 aactccccca cgtttgagtt gactttgact actatcacca gcatcttgga agccaacgcc
    56461 atcatcctca atacggatga ccaatcccga atcctgtttc tggacagaaa gtttaatatg
    56521 gccctgacct tccttttcct taatgccatg gtaaagagca ttttctacaa ggggttgtag
    56581 gaccagcttg ggtaagacta aattatcaaa ggcaacattt tcattaattt cgtattccag
    56641 cttatctcca tagcgttgtt tctggataaa gagatactgg cggacatgat tgatttcgtc
    56701 agagagacaa atcaagtctt tgccttgatt gagtgccaag cggaaatagg ttgccaagga
    56761 cttggtcacc tgcaccactc gctgactatc atgaaattca gccatccaga tgatggtgtc
    56821 caaagtgtta tagaggaaat gtggattaat ctggctcgaa agggcttgaa gttggtactg
    56881 acgggtcgtt tcttcctggc tacgaatagc taccatcaac tgatcaatct gatccaacat
    56941 ggcattaaat tggcgagtta cttctctcag ttcataggca ccaacttcct tggcacgaag
    57001 attttgagca ccagaagcaa tttccaacat ggtttctctc aaatccttca aaggagcaat
    57061 ccagcgttta agactgaacc acactaagca gagacagaca agaagagatg tgacactggc
    57121 cccaagcaag gtccacaaga gctgactccg aacctggtct aacttttcca atgatgacac
    57181 gccaagtacc gtccaatcag ttcctgcaat cttctcttga ctgacgtagg atttgtgacc
    57241 aggagtataa ccctgacctg tctcgatgta gggtttcata gcctccattt tgctagacga
    57301 actataaact gtgtgttgag gatggtagac aaattcatgg ttttcattga taatgaaggc
    57361 aaagccctgc tgccccaact ggagttgatt gagataggct tccagagttt cataagaaat
    57421 atccaaacga agcacaccaa gattggctcc ctttgcatca acaagttctt gagtgacaga
    57481 aatgacccac tgactatctg atttacgagc tggagtcaaa acaggcatag ctccctgatg
    57541 aatggccttt tggtaccaat cctcagccat catatcagag gaagttttca tctgcacact
    57601 gtcatctgta gaaatgacct gaccagattt ggtcaccagc acaacagttt tcaagtcctt
    57661 atctgacttc aagatggtca aaaacaaatc tcggattccc tcgaccttgt cttgactggg
    57721 attctcagca taggccagaa catccgtctg ctgggtcaaa ccggtcgaag tggtttctag
    57781 ttttttgata taagactgaa taaagtggct agtctggctg atggtcgttt ggctgttgcc
    57841 ctcaatggtg gcctcaatgg ctgaagaact tgattgatag tagaaagttc caaccagagc
    57901 taggagaatg agaaagacca gaaagatgga aataaccatt ctaactaaaa gagaagaacg
    57961 cttcatcggt cttctccctt cttaaactga cgaggtgtca cacctgcaat ctgcttaaaa
    58021 cgttgggtaa aatagttcat atcttcaaaa ccaaccttct ctgcgatctc ataaatcttc
    58081 agatctgtag ttaaaagcaa gagcttggct tgtttaacac gttctctcac tagataatcc
    58141 tgaaaaggca agcccaactc tttcttaatc aaggaactca gataggtcgg actaaaacct
    58201 aagtcactgg ctaaagactt taaactaaat tggctatcag ccagatgaga ctggattttc
    58261 tgggccatgt ttccttcaaa cctattagtc aataaatctt gtaactgctc ttctttctct
    58321 tccttgtcta gtttttgttt gattttcccc aacatttcct caatatcctg acgagaaaag
    58381 ggtttgagca ggtagtcgtc cacacctagt ttgacagcag acaaggcata atcaaaatca
    58441 tcgtaacctg ttaaaaagac caaatgaacc tgaggatagg tttctcgtac cagactggcc
    58501 aactggatgc catttagatg aggcatgttg atatcggtta aaatgatatc tggaacctgc
    58561 ttttggatca attcccaagc ctgccttcca ttttcagcct gaccgatgat ttccatatcg
    58621 taggctgcta cattgaccag tttagtcaaa ccttgtctta ccagatattc atcttctacg
    58681 attaagattg tgtaggtcat gctctgctcc tttaccactt actagtatca gtatagcaaa
    58741 attctcctct aactgcttag gaaagacctc ttatactcaa taaaaatcaa aaagtaaact
    58801 aggaagatag ccacaggttt ctcaaagtac cgctttgagg ttgtagataa aactgacgaa
    58861 gtcagctcaa agtatagctt tgaggttgta gataaaactg acggagtcag taaccctaca
    58921 tacggtaagg cgacgctgac gtggtttgaa gagattttcg aagagtatta atcaacataa
    58981 tctagtaaat aagcgtagcc tttttcttcc atttggtctt tgggaataaa gcggatagag
    59041 aggctattga tacagtaacg taagccgccc ttgtcctgtg gaccatccgt aaagacatgc
    59101 ccaaggtgag aatctcctac tcggctccgc acttccatac gcgtcatatt gtaggactta
    59161 tcttccttgt aggtgacaac atctggactg atgggttggg taaaactagg ccagccacaa
    59221 ccagactcaa atttgtcttt tgatgaaaag agaggttccc cagttgctat atccacatag
    59281 ataccggatt caaatttatc ccagtaacgg tttgagaaag ctcgttctgt ttgattttcc
    59341 tgggtaactg catactcctc aggtgacagg gtctttttca attcctcatc acttggtttt
    59401 ggatatttgc tggcatcaat gacaggatag gccgcctgat taacattgat atggcagtag
    59461 ccatttggat ttttcttgag atagtcttga tggtaatcct cagccaccac aaaattcttc
    59521 aagttttcct tttcaactgc tagaggttga tcgtatttct tagccacctc atcaaagact
    59581 tggttaatca cttccaaatc cttgtcatct gtgtaataaa caccagtacg gtactgggtc
    59641 cccacatcat ttccttgttt atttttgctg gttggattga taatgcggaa atagtgaagc
    59701 aggatttcct tgagagaaat ttgcttggca tcataggtga catggacggt ttctgcatga
    59761 cctgtttggt taatcaattc gtacttggtt gtttctcctc taccatttgc atagcctgaa
    59821 acggcatccg tcaccccggg aacgcgtgag aaatattcct ccactcccca gaaacaacct
    59881 ccagctagat aaatttcgtg caagtctgcg tctttactaa tttctgtttt tttcactgtt
    59941 tttcctcctt ggctaactgc cgccttttca atttgcgagg catctgtctg ccctgcattt
    60001 cgtatcaata gaacatagaa accggttatg gatagaaaaa atactcctag caacaagaag
    60061 atttttaact tatcattcat aagacacctc ctaagctaat tccttcaaag tttgcaaaat
    60121 tgcatctttt tccatgaatc ctggatgtgt tttgaccagc ttgccttctt tgtctataaa
    60181 ggcttgggtt gggtaagaac ggacaccata agtttccaaa agtttgcctg atgggtcaac
    60241 taggactggg agatttttat aatccaatcc cttataccaa ttcttaaagt ccgcttcaga
    60301 ttgctctccc ttatgtcctg gtgacactac tgtcaatacc acatagtcat caccagcttc
    60361 tttagcaatc tcatccgtat ctggaagact agccagacag atggaacacc aagaagccca
    60421 gaatttgaga tagactttct tgcccttgta atcagataaa cggtaggtct tgccatctac
    60481 tcccatcaat tcaaaatcag ccacctcttt ccctttagct gcgcttgttt tactagctgt
    60541 ctgctccgtc ttcatttcat ctttcgtttg gtgttcacta gtcacggact tgcctgaaca
    60601 agccgtcaaa caaaggagcg aacctgctcc aagaacacat gtttgccatt ttttcatatt
    60661 gatattcctt tccattttat tcaaataatt gacttaaaat tgaagcattt ccaaacagaa
    60721 ccaagagtcc catcacaata atgagaaaac cacccacttt tttgaggatt ccgagatagg
    60781 gatgaagttt ccggaaatgt ttcaaaacat aactagaggt cagagctaga agcaagaatg
    60841 gtagcgccaa gcccagcgta tacaccaaca tgagaccagc tccctgccaa gctcctgaac
    60901 cacctgaagc cgccaaggcc aaaacagacc ccagaaccgg ccccacgcaa ggcgtccaag
    60961 caaaactaaa ggtcaagccc aataaaaatg cctgactata gcccttacca ttttgcccct
    61021 gtccttgcag ttgtagcctc ttttccttat aaagcccctt aaagtgtaga atctccattt
    61081 ggtgcaaacc aagaaggata ataattgccc cagtaagata ttggaaccaa gaagcataaa
    61141 gcaaatcgcc taaaaaacca gctccatagc ccaacaaaat aaatataaag gaaattcctg
    61201 ctataaaggc cagagttcgt aataaactag taactgagat tgaaaatttg ccgctagaag
    61261 cctgagcacc atccttatca tctagtaaca ctcctgtata gaccggtaac aaaggtaaga
    61321 tacaaggaga aaagaaggat agaatccctg ccaaaaagac acttagaaaa aagaaaatat
    61381 gacccataaa gttcctccta tcattttatt gatagattta ttatactcct tccattttcg
    61441 aaaaaacagg gacaatgata ggggaaaata ggaatttaat cagatgattt agaaatcttg
    61501 gacaaaaact atacaaaaaa ctgtcaaagc acaaaagcgc aaaagcgcat agtatcaagg
    61561 ttctataaag tcttgatact atgcgctttt ataatggata aatagttagt cttttttaaa
    61621 gaccggatct ttcaaactct gcatactggc attgataacc gcgcctagga taacaatttt
    61681 agcaatcaag ataaaccaaa acatcataac aacaagaaga acggaaccta aaattcggac
    61741 atccaccaaa tgatggacat agtaattgag ataactagag aacagagtta gtaaacctaa
    61801 aatcactaag agaacaaagg cactgcctgg tagggtatag ctaattttcc tgttagatag
    61861 attgggaaga aaataataaa gcatgaccaa gatagcaaag aggagggcgt aaatcagagg
    61921 acctgccaac ccttgtaaag cctgatagat aatgccatct tttgtccaat aatgagcaag
    61981 taaagccaaa atcatctgac caaataagat caaaaacaag gcaaacgcaa agaggagctg
    62041 caagccaaaa ctgactagga gactcagcat ctgatgggaa ataagtccac gactcttttc
    62101 gacgccataa gccttgttaa aagctttttg caagaaattc atagattttg aaaaactcca
    62161 taacgccgat aaaacagaaa aactcaataa acctgttgaa ggttgcgtca agacttctct
    62221 ggctattttt tccacacctt catagaggct tgggggcagg acgtctttca taaagcccag
    62281 aaattctccc acaggaatct gaaaataagg gaggatattg accaccacca aaagcagggg
    62341 gaaaatcgaa atcaaccaat agtaggctac tgcgacactg gtcaactcac tatctgatgc
    62401 ttgataataa tgcaaaaaag cttttaataa aggcttgtct atcagctctt tccaccattt
    62461 tttcatgtca cactccttca cttacaatct tatactcaat gaaaatcaaa gagcaaacta
    62521 ggaagctagc cgcaggttgc tcaaagccct gctttgaggt tgtagatgaa actgacgaag
    62581 tcagtcacat atataatcca aggcgacgct gacgtggttt gaagagattt tcgaagagta
    62641 ttaactaatt tcttcttacc aattccacca tatcatacgg cagggtattg gcagcttcct
    62701 tcaaggaata gttctctaag ttatttacat tttgtcgtaa tttcttggca tacttagtcg
    62761 taatcaatcg tttttcttcg tattcgaaaa tcaacttgcg ctccagataa tagcctctca
    62821 gcatttcatc gatattgttg ggtttgacac gattgataac ccgttcgaca aaggcaccac
    62881 tgctgataat agctgtttct cgaagacgag actcctgcat aaaactaatc aaagagcgtc
    62941 tgtagactcc cttcaggttt tccaaacttt caataatcat ctctgtattg gcaagataga
    63001 gctctgcaat ttggtcataa tcaagagcac ggagacggct ttgctccttg tccttccagc
    63061 tacggaaggt ctttccaaga gtaaaaactt catgaagaag aaaacgtaaa atcctcaagg
    63121 aaacaagaaa ataataggtc agtcttgagg caagtttacg attgattcct tgttctatat
    63181 ttttcagata acgttggtaa actcggtaag cacgattgct aatgttcccc tcttcatagg
    63241 cctgttccaa accatcactt tcaatactaa gaattaagag tttcaaagca gcccagtctt
    63301 cttgatcatc ctggttttct tggcttaaaa tgagattttc aatacgtcca tgataattgt
    63361 caatagccgc atagagggga agtttatttc tggtgtcttc caactctttt tccaactcta
    63421 gcgttacttc attcaaaatg gcgatatgca tgagataatc cttgctttct tcctcttcat
    63481 cagaaagatg aggcaagacc aagagacctg ttaaaaagct gacaagcgtc acacctgcaa
    63541 caaggaaaag caagagagga tactcctgtt ctagattact tggtatcaag agaatcgtag
    63601 caatcgacac cgttccctta acacctgaaa aggtcaagag aaacatgtcc ttcatatact
    63661 tatttagctt tttctttagg cgtcgggttc tataggcata atagccatag atcataataa
    63721 aacgaatgac aaagaggaca aaggtaaggg cgatgagaga tagcaataaa agtagaggat
    63781 tatagattgg attggtcaag ataggttctg ctatcatttc cagctccatc cctaaaatca
    63841 caaagacaga accgttgagc ataaaggtca ctgtatgcca gaccgtctcg gtcaccgtat
    63901 ccacttgggc ttcgaggagc gtgattttct tgaaacgact tgcctttaaa attccagcaa
    63961 ctacgacggc aataatacct gaaacatgaa cttcttctgc cagaaagaag gtcacaagag
    64021 gcaaactcaa ttctaataaa agttcactgg caatatccgt tgcacgcaca cttagcaaga
    64081 aggtatggag gaagcggttg gtcatggctg ttaaaaatcc aattaaaaaa ccgcctagga
    64141 ttgaaaagat gagtgaactg ctagcttgcc ccagagaaaa agctccagtt gtccaagctg
    64201 tcaaagctac ctgaaaagcc accaaaccag aagcatcatt caagagtcct tcgcccttaa
    64261 gaatattgga cacgcgctta ggaaagctaa aacgctccga aagagaggca aaggccacca
    64321 agtccgtagg accaagggct gccccaacag ccaagcaagc tgccaaggga aggctgaacc
    64381 aaagaagatg ggccaagcca cccaaactca gggtcgagat aaaaatcact ggaaatatga
    64441 gataaacaat gattcgccag tgttttaaaa tagccgtaac atctgcttct tcagcctctc
    64501 ggaaaagcaa ggggccgata accagtgcca aaaacaactc cgtattaagg tgaaagtcag
    64561 tattgggtaa aaagagacca atcacaattc ccaaaagaat ctgcaccaaa gggagaggca
    64621 aaaagggtag gagcttattg gttgtacttg agacaatcaa gaccagtaaa aataggatga
    64681 ggtaaatcag taattccacg cacgtcctcc ttaatctttt ttacaacagg attcaaatat
    64741 ctccttctgc tctttgattt tttggtcaat cttggaacag tctttgtgct caatttttct
    64801 ctggcaccgt tccatttcaa gagcaactaa ttttttcttg attttaagca tttttttgct
    64861 catatgcgct tggtctagca cgcccaccgc tcgttcgtgg taggttgatt caacaaaatt
    64921 ctggcgcatg gcatccagct tttcgtgtag gtattgttta tccatgtctg tatctctcta
    64981 atttttcaat catcactaaa aacggcgggt tgttgacttg gtttaaagtt cggtaaatgg
    65041 cagctgtgta ctcttgttgg ttcaactgga tcacaaaatc caagacagca tctctctcga
    65101 ggtcgcctcc ttcatgacca tagtaaatca taatagcaat tcgtccacct ttgacaagta
    65161 agccacatag cttttctaat gcctcaatcg ttgtctgcgg tcgggtgatg acagacttat
    65221 cagctgacgg caaatagccc aaattaaaaa tccctgcctt agcttttgtc acaaactggt
    65281 ccagtgtctc atggccttgc aagattaact gggcatttgt caagccagcc tgatgcaaac
    65341 gctcttgggt cttttccaag gcttgcttct gaatatcaaa ggcatagact tgcttggcta
    65401 gcttggctaa aaaaagcgtg tcatgaccat ttcccatagt cgcatccact acgacatcct
    65461 cttttgtcac gacctcagcc aaaaaatcat gtgccatctc aagtggtctt ttcattttca
    65521 aactcctgtt ttacagcctt gcatccttga acacttccac gacgtctcat ctccatctca
    65581 atgctgttga ggacttccca tttattgagg ctccacatag gaccaatcag catatcccta
    65641 ggcgcatctc ctgtaattcg atggatgacg atatgtttgg gaataatttc cagttggtca
    65701 cagatgaccc tgacatattc gtcctgactc atcaattgta aacgtccctc atggtaatct
    65761 cgttgcatac gagtatttgt cataagatgg agcaaatgca gtttaatccc ttgaatatcg
    65821 ttatccgtga cacaacggcg gacattttca accatcatct catgggtttc accaggcaaa
    65881 ccattgatca aatgggaaac aatctcaatt tttggatact ttctcaaacg cttgaccgtt
    65941 tccacctaca attcataaga atgcgcacgg ttaatcaggt cagaggttgc ttcataagta
    66001 gtctgcaagc ccaattcaac cgtcacatgc atgcactccg ataactcagc caaatattcg
    66061 atggtttcgt ctggtaaaca gtctgggcgc gttccaatat tgattcctac cacacctggc
    66121 tcattgatag cctgttcata acgctctcga ataacttcca ccttttcatg ggtgttggta
    66181 aaattttgaa aataaaccag atacttctga acatctggcc acttacgatg aataaagtca
    66241 atttccttat aaaattgctc acggataggc ggatctgggg ctacaatggc atctccagaa
    66301 ccggaaaccg tacaaaaagt acagcctcca tgagccacag ttccatcacg attgggacag
    66361 tcaaatcccg catcaatagg gactttaaaa gtcttttctc caaagagttt tcgataataa
    66421 tcattcaagg tatcataaga ttttataact ttcattataa caaaaatcac ccacaatctc
    66481 aaaagcctga ctttcctata aattcctctg tttctcgttt ccattagcct ttttttatga
    66541 tacaatatgg gtatgatttt aatgaaatta gcatctattt tattattgat actgacctta
    66601 gtcgtctgca ttatcctaac caaacttttt agattaaaaa aactaggacg aaactttgcg
    66661 gatttggctt ttccagtctt ggtatttgag tattacttga ttacagctaa aacctttacc
    66721 cataatttcc tccctagact ggggctagcc ctctcgttcc tagccattat tctcgtcttt
    66781 ttcttccttt taaaaaaacg cagcttttac tatcctaaat tcatcaaatt cttctggcgt
    66841 acaggatttt tattaaccct tatcatgtat atagagatga ttgttgaatt gttcttaatg
    66901 aaatagtcga atccctaagc attttctagg gatttttgct ttctctacaa aatagtatag
    66961 acaataacac tatacaattt tatacaaaga aaagagtctg ggacaatagt ctcttatatc
    67021 caaaaaaggc aacggatttg ccgttgcttt tttgcatggt tacgatagtc ttggtaaaat
    67081 agaattgctt aataaaccat ttagaaaggc tatcccatgc atattcacta taacacaaat
    67141 caaacaactt taccactaga aatcagttcc ttcttaccac aagaccatct cgtctttact
    67201 attgaaaaag tggtgaatac cttggaggaa cgtcacttct acacctccta tcatgccttt
    67261 ggtcgcccgt cttatcaccc taaaatgctt gtatctactc ttctatttgc ctattcacaa
    67321 gggattttct ctggtcgaaa aattgaaaaa tggaagagtt agtgacctta gattgtttgt
    67381 ttattgacgg aactaagatt gaatccaatg caaacaagta tagttttgtg tggaagaaaa
    67441 cgacagagaa attctccgcc aaacttcaag aacagataca agtctatttt caagaagaaa
    67501 tcactcccct tctgattaaa tatgccatgt ttgataagga acaaaagaga gggtataaac
    67561 agtcagctaa aaacttagcg aattggcact ataatgacaa ggaggatagc tacatacatc
    67621 ctgatggctg gtgctatcgt tttcaccata tcaagtacca gaaaacacag acagactttc
    67681 aacaggaaat caaggtttac tacgctgatg aacctgaatc agcccctcaa aagggactgt
    67741 atatgaacga acgctatcaa aacttgaaag ctaaagaatg tcaggcgctt ttatctcccc
    67801 aagatagaca gattttcgct caacgcaaga ttgatgtgga acctgtcttt gggcagataa
    67861 aggcttgttt gggttacaag agatgtaatc tgagaggcaa gcgtcaagtg agaattgaca
    67921 tgggattggt acttatggcc aataacctcc taaaacatag tgaaatgaaa taagaacagg
    67981 acaaatcgat aaggacagtc aaatcgattt ctaacaatgt tttagaagta gaagtgtact
    68041 actctagttt caatctacta tacaataaga gaacgactca aaattaaaaa gctagagttc
    68101 cgcaattgga aatatctagc ttttttgtgg ttgagaacta ttttgttcca gactctttat
    68161 cttctattta ggacaagagt ttttctttgg tctttaatga taaagaaggt atcaaaattt
    68221 ctagtcttct tttttacctt tagtaactac taatcctgca ctcaaaccta gaagagctaa
    68281 acctgctgct actgctgctt ggcttgacgc actacctgta tttggtaact gggctttatt
    68341 agtttgacta gcttcacttg aatcaattgg ttttgtatct gctttttctg acacttgtgg
    68401 ttttttagct tcttgagcta ctggtttggt tccaaccaag acgatgcggt ctgtcggagc
    68461 ttctaccact tcacggagtt tttcttcctt acttccatca ggattaatcg ctgtaaagat
    68521 acgttcttta ccagtttttc cttcttgttc tacacgagtt tcacctagat acagtgttga
    68581 atcttttttc tcaactgtct tgtaggccaa atctttttca acaaattcga gttttggaag
    68641 atcttcttgt acagcagcaa ctgtcttctc agaaactggt ttttccttag tcaactggat
    68701 acggtattcc ttaacttgtt ttccactttc tgaaacgagg cgaacaagta ctggaaggct
    68761 atcttctcca ctatctacca cagttgaagc tacttgattg ttttcttcaa ctgagacttt
    68821 tggccgttga cctttatagg taatttgata gtcttgacga ttttcagcga aatcagcaag
    68881 ttcttttcca tctacaagaa tcttcgattg cgtgctttct tgaggcaatt cacttggtgc
    68941 aaggaaggtc atctcaatca tcgcaacacc gctcttatct gctttacgct ccatacgcca
    69001 tctcatagct ttggctttga cagctttaaa tgttacgttg atttcatcac cagctgcgat
    69061 gtctttatcc gcacgataag gcacagcttc ccaattttct ggattgttga atggatggtc
    69121 tgcgtcgtag gcttggtagt ttgaatagta ggttggcact tcaaactctg gaccgacata
    69181 gcgttctaaa acgagtttag ttggtgcatc cgtaccacta tctgcaaaga agtgaagttt
    69241 ggcttgcgca acagtccgtt ctacaatctt accattttca cggaagatca cacccgctga
    69301 tacttctgga ttagaagatg gtgttggaga ccagtttgtc caacgacgat tttctgaatg
    69361 atctccgtca ttgagatagt caacgcggtc atgagagttt ttgtcaatat cattggttgc
    69421 tgaagcaaag gcctggttac tgttttcatc atagttaggg ttatctgaaa gagcttcgcc
    69481 tagtttgtct gtcactcgta cagtgacctc agcaacaaga tcactaccaa ggacatggcc
    69541 tcgaacggta aattgacctg cttttgtcag attttctgct ggaacttctt cccattcaac
    69601 tgacaaatct tttgtttcgt agccgtcttt acctgtgaag taaactggaa ccttagtcgg
    69661 caattcaagt gcttgaccta cttgtagcaa gcgagcttgt ttaaccgcag caactggttt
    69721 atgagaaagt aagttcttat ccttagtgaa gtgcagacgg tattctccta agatgtcgcc
    69781 attttcagct ttcgcgatga cacgaactgg ctcaccttca cgaacgcttg gaacgacggt
    69841 agcgagacca ttgttgctaa cacttgctgt gactgccgga acttttccat ctacagactc
    69901 aaggtagtag tctgtcagat cagggttgaa gtttgctaag tctttaccgt caacttggat
    69961 tcttgtttgt ccttgcttgg ctgccgcaac ttgtttcgca aagatttgta cctctgtgat
    70021 agacgttcct agtttgttgt ctgctctcac catgcgaata cgaacagcat aggtttcaac
    70081 tttatcaaag ctaaagtggt tcatttctcc agccttgagt tgagcagggg cttttagatt
    70141 agtaactggt ttccagttgg cagaatcatt aaagacatgg tcctcattac caacaaaact
    70201 agggttttta ggagctgttg ggacagtctt accaacataa tactcaatca cataagactt
    70261 cggtgcacca actccatggt cttcatggaa gccaacgctt aagttatcaa ctgaacgttt
    70321 gctcaaaata cctgaatctc cgaataggac accgactgaa gcttctggat tactacgatt
    70381 ccagtttgtc caacgattgg ctggttggtt attgtaggaa atgagcttgt cattaacatt
    70441 tgaaactggg tcgcttggat ttgaatctga agcaaaggca agtggcaatt ctgaaccggt
    70501 ccattggtca gaaatgtttg caccttgctc agtttgagca gatacgcgaa catgaagttt
    70561 agttgttaat tgagtacctt ctaagcgacc attaactgta aagacacctt ccttagcgta
    70621 ttgctctgga cgaatcgcat cccatgcaac cttagctgat gaaacgtgac catttgaatc
    70681 atatatccga acactttctg gtaattgtgg tgcttctgcg attggagttg tcacactgac
    70741 ttcttcaact gaaacgatac cttctacaga gacttttgca cgcgcttcaa ggtcaattcc
    70801 ttcaacttta cctagtactt caaatgtttg ataggagtct agtttttctt tcggaatagc
    70861 ttgccaagtg actttatgag ttttagggaa acctttgtca tactcaactg ttactgttgc
    70921 tggaagactt ggttcctgat gcaaatctgt cactacattt acaggacgga tggattgcgc
    70981 aatcttcttc tcagtattgg cttggatagt gagttcaact tggcctttag ctccctcata
    71041 ttcagcgttc aaagtgactg ctcctggctt atgcaactca agcattcctt tacgaattgc
    71101 gacttcccct tcaccacttg tagagaaggt tactttatca gctggtaata cagcttgcgt
    71161 tccatcttga tagtgagctc gaaccgacaa tttgacagtt tggtcttctt tgagactgtc
    71221 agctttttcc acttgcaagc tcaagtgagc aatttttggc gcttcttcaa ggaattgaat
    71281 tgcataggtt tgaagagggc caccatcttt aggctgaata aagatgctcg cacgcatgcc
    71341 gtttgctgcg cttgcttgaa gaactgtaac agctgcattt ttagcacttg ctgtgacttc
    71401 tggcaactta gctccataag caagagtgcg gtattgcatt ggtttttgac tagtaagacc
    71461 tgtgacagct tcaccaccaa ccgttacagt tggtactgca ggtgccgcag gattgccttc
    71521 ttctaccaca agggttgcat gaattggttg accttctaaa taaccggtcg cttgaatacg
    71581 agaacctgga attgctaact tagctttatc ttcttcggca atctcccact tgtccacttc
    71641 atactcttca acacttccat cagtcaaaac ataggaaaca gatttgtcta cagaattcaa
    71701 gtcagtattt ggagcaatac gtttcacaac tggtagctct gatttaagag caatcacttc
    71761 tacacgagct tctacttctc gtccgtcagc catacctttc accgttacaa taccaggctt
    71821 gctcacatct actgaagacc aggttacagg acgttctgca cggctaccat cactgtatac
    71881 aaacggaaca gtggtaggca tttcaggtgc ctctccaata atggtctgta cttttggcac
    71941 ttctgtcccc aaaacagtct tctcttgtcc ttctttctta ccagtaaaga cagtgacttg
    72001 gttcgatttc aagagatcag agtgggcagt aagggtgaat ttccctgctt gttcagttga
    72061 tttgacaatg gcaacacctt taccattaaa tgctttacga atccaagaac catctgcttg
    72121 cgccttatag cgttcacgac tggcttgttc tccgttatct acaccgacca gttgaccttg
    72181 gccatgcaat tggaagcgaa ccagattatt agcagttgga accacattcc cctggctgtc
    72241 aacaatttca tagtagatgt aagtcaagtc ttttccatct gctgcaatcg catggtcttc
    72301 cttaataaga cgaactgccg ctggcttacc agcagtcgta atcttatctc gagcaatttc
    72361 cttgccagat tcatcacgag caattgcttc caaggtaccc ggttgatagg caactttcca
    72421 ttcaagataa agttcattag catttgcacc ttcttggtaa gtccgcccat cgctggtttg
    72481 ttttttattg aaagtcttaa gaccaagaga ttttccattc aagaacaatt ctacactaga
    72541 agcattcgaa taagcacgaa ctggaatctt accttctgag tcagctactt tggatgctaa
    72601 ttctttgttt tcccagttcc agtgaggaag aaggtgtacc atcggtttct ttttaacaga
    72661 aacccattgg ctttggtaga ggtagaagtc atgttttgga atgccggctg tatctacgat
    72721 accaaagtaa gagctcttaa caggagtttg attttggttg tgccatggtg taggttcacc
    72781 aatatagtcc gtacctgtcc agataaactg tccagcatag ccagcgttgt cacggtcaaa
    72841 agtccatgaa gcggttgctg ttttccccca accaacacga tcatttccat aatctgactg
    72901 ttcataatta cgctcaggtc cattgctatg tttcaattca cgttcagggc gatagtaact
    72961 tcctcgtgta cgggttgctg atgatgtttc tgaaccgtaa atcaaccatt ttggatgctt
    73021 agctctaagg gctttgtaat tatcttcaga atagttaaat ccaacagcat cgagttcatc
    73081 agcaattttc tcatgccctc cgctaccatt accgaaacgg aatttatctg ctcccatggt
    73141 aacatagcga gtcttatcaa catccttgat aaccttgacc aaacgtttaa cagttgctaa
    73201 agagtgggca tcaccattag cttcacctat ttcattacca attgaccaca tgaagatagc
    73261 agggttgttt ttgcctcttt cgaccatggt acgtaggtca aaatcagacc atttttcacc
    73321 ttttcgagct tctgggtgag tggcatcttt ttcaaaaaaa cgtccatagt cataaggttt
    73381 cttgccacca taccaagtat caaaagcctc ttcctgaacg agtaaaccta gttctgctgc
    73441 gatttgcaag gtttgctcac tagcagggtt gtgggttgta cggatggagt taactcccat
    73501 ctccttcatt tgtttgagac ggcgatattc tgctttatag ttttcttctg ctccaagcgc
    73561 cccatggtcg tggtgcaagg atactccatg gaatttaata cgttcaccat tcaaagagaa
    73621 accttcattt ggagtccagt gatagtaacg gtaaccaaac aaatccttct tagcatcaac
    73681 caattgaccg tcacggtaaa cacgcgtaat caattcgtac aaggcaggtt tgtcatttaa
    73741 aacggtccag agttttggtc tttcaacttc taaaatcgca tctaggcttg ttgattcatg
    73801 tgcttttaag gtacgactcg ctgtacgaac taagcctgtt acagcatgac cacctcgttc
    73861 aacgatttga tattcggcta caagttcatg gtctttgtcg tccgtattga cgattttgct
    73921 ggtcacatga gtttcaacct tgccatgttg ttgttcttca agttttggtg ttaaaatagt
    73981 tgtcccattt ttctcaacat gcaccttatc tgtcacttgt aaagtcacat cacgatagat
    74041 accacttcct gaataccaac ggctacttgg ctgtttgttg actgcatgga cagcaatcac
    74101 attctcacga ccatctttgt gaaggtattt ggtgatatcg tatgagaact ggttataacc
    74161 atttggataa tgccccacta actgaccatt gacataaact tgagaatcca tgtagacgcc
    74221 atcaaaagta aggcgaacat ttttcttgag gtctttttca tctagtttga aagtcttgcg
    74281 ataccaagct tccccaccgt tgagctgtcc accttcattt tgtgcaggag attcatgatc
    74341 gaaatcgtta aagatactcc agtcatacgg taaatctaat tttttccacg tagatacgtc
    74401 tgcatcaggt ttaatggctt ccttagaatt tgcattgagt ttaaagtacc aattttgatt
    74461 aaaatccact ttcctgtctt caatcatttg attcacttct tcatttgtta cagctttagt
    74521 atcttccttg agcggttttt cttgacttga agcttgtgat tctatccttg gagctttttc
    74581 ttccggttta gcagacactt tttcctcttt tggagttacg gcttcatctt ctttcttctc
    74641 agatgcaata gcctcagttg aactaggttc actttgttct gtcctttcaa ctacattttt
    74701 agtttccaaa gctttatcag ccttttcttc tactatcatt ttttcctctt taggtttctc
    74761 agcagtatga gtaataagtg tttcatccgc ataaactaca gattctccag ctatatttcc
    74821 tcctaataga actgcacaag tcccaatcat tactgagcaa gctcccacag caaacttacg
    74881 aatgctataa actcttttcc gattccaatg gcctttcccc ataaaaccct ccttatatta
    74941 tatttagtgc agttagctac taccaaagcc caagtggtat acatggtatg acaacctagt
    75001 ttcaacaatt tacactctgc gaaaatccaa ttcaaacttc gtcagtgtcg ccttgccgta
    75061 gatatgatta ctgacttcgt cagtttcatc tacaacctca aaaccatgtt ttgagctgac
    75121 ttcgtcagtc ttatctacaa cctcaaaact gtgttttgag caacctgcgg ctagcttcct
    75181 agtttgctct ttgattttca ttgagtttat attttatagg agcgcattat tttgcttttg
    75241 ctgcgtactc ttcgttacgt ttgatcattt gttttctgta ccaagcaaag ataccgatat
    75301 agaatacaag gaaggctact gcaccaagga ttgctttgat atcaccagtt gtagtgttac
    75361 caattgtcca accaagaagt ttttcgattg gtccttcaag agtagagtga gtaatcaatt
    75421 gagtttggct cacaccttct gggaaggcac ctacaccttt agcaagttct gttgcaaatg
    75481 gtgcaataag ggtacctgaa agaaggaaga gtggcaacaa gagtgttccg aagataatca
    75541 tacggagcaa tttaccacga gttacaacca agagagctgg agtaacaccc atagcgatga
    75601 tacctgcaag tggcaagata ccatttccaa cttttgaaag aagcactgct tcaatcaaca
    75661 tgattggtgc aagtacgttg gcacaagccc agatttcagc acgaccagcg atgaatggcc
    75721 agtcaagacc gatattgaat ttacgtcctt gaagacgttt agtagcaacg tttgtaatac
    75781 cttgtgatag tggttctacg gctgcgatga accatgaacc gataagtgag aagagttcca
    75841 aagatacacc ggcagtcaaa ccaagagaca accatccttt gataacaaga cgccatttat
    75901 ctgcatctgc aacacctgca attggatgtg gagttcccat aataccgata acgataccaa
    75961 ggatgaaacc gatgaagaat ttagatcccc agaaaccgat tttcttgttc aatttagcag
    76021 catcaaagtc atatttatca aggcctggga agaatttttc aaaaatctta tccaaaacca
    76081 tgataactgg gttcatcatg tagttcatgt gagttgatgt cattggtgat gaacttgggg
    76141 cgttaagaag gtcatcaaat gtaggtttca tcaagtcaga gttgataatt ttcaacacac
    76201 cgacaagaac gatagctgct gtagcaatca agagtgaaac cccttgactc acaccattgt
    76261 tatcagcata ccatttaatc aagagacctg tgatagacaa gtgccagata tcaaagatat
    76321 cgacatcaag tgtatcggtt ttcttcatag caagcatcac tacgttgaca atcaacatga
    76381 tgagcaagaa gtaaagtgtc caagcagaac cccaagtgat tgttgcaagt ggtgcccaac
    76441 caacgtcggt aatactcaat tgtataccag tgttttcaac gaattttgca agtgatgctg
    76501 agaaagcacc atttagcata ccgatgatag caccgatacc tgtaagagcg atggcaagtt
    76561 tgataccacc ttcaagcgct ttggagaatt tcactccaaa aagtaaagcc aatactgtca
    76621 aaatgattaa catgatgaca ggtccaccca tttctaagat gggattgaaa acctttccga
    76681 ttaggtcaaa gattgcatcc ataacagttc ctcccttttt tatgttatat gaatgttaac
    76741 aaattagaat tagcttaatc cgtgttcttt aatagctgct tcaatattgt caaatactgg
    76801 agcgctcatt gctgggatac ggaataagat tggtccagct tcgataactg ggatacctgg
    76861 ttcaaaacca aggtctgttg cagcgattgg tgtaaagata tcgtaacctt tcataaggtc
    76921 ttcgtttaca tctttcacca tgactgcatc acagtgaaca tcataaccac ggtttgaaag
    76981 ttcttcttct agagcacttt taatttggtg acttgagtta acacctgcac cgcaggcagc
    77041 aagaatttta atcatttaga tttcctccga ttttattttt taatagacaa gattaagcgg
    77101 ttgcttcagc aatgtaagca taaagttttt ctggttcgga aatttttgat aggtcttcaa
    77161 gatgtccatt tcctgtgaaa aagtccatca actgagccag aatatttgtt tgacttgaac
    77221 ttgagttatt gatgataaag aagagcaagg atacttctac ttccttatca ggagctatca
    77281 tattgtgaaa agttactggt ttttctaatc gaacaaccac cactttctca gctagattat
    77341 gaacaatatc tgtatgagga atcgctacat ttggcaagtc ctttcctaga aattccatat
    77401 ctaaaccagt tggaaatgac ttttcacgcg tgatcaaggc ttcacgataa gttggagtga
    77461 caatttctcg ttcttccaat aaagttgcaa cctgatcaaa gagttgttct tgattatccg
    77521 cttctaagca aaacacaagg tttttgtcaa agaaataatc taataccata aggttttccc
    77581 ttctttccat taactttatg ccataagtat aacactatat gaaaccgttg tcaattactt
    77641 tttgttcttt tttgtctctt tttttatatt tttgttttgt ttatagtttg ttatataaaa
    77701 acaaacacac aaacaaatac tccaagcatt tttgctgttc taatattcaa tgaaaatcaa
    77761 agagcaaact aggaagctag ccgcaggttg ttcaaaacac tgtttttagg ttgtagatag
    77821 aactgacgaa gtcagtgatc atatcgtaac cgcccaatag acttcgttat tgggcggtta
    77881 cgaaaaactt ccttccaaat aaaaaggaat taagcaacca aacgctactt aattccttga
    77941 aattgtctca tcacctctat tagcctttaa attttgatag actctatttt ctaatcaata
    78001 tgaccaatat tgtcaatact aaccctttca atcaattcat tagttatcta aactaagtcc
    78061 attaataact ccaaatagta tcaatagtga agtaagctaa ataattgagt tataaatggc
    78121 tgttttcaca aaactatgtc atcacctcac tatctaatct cagtacataa accatttttt
    78181 tctatagctt ttgtcttaat cttgattttt tttcttcaat ccaagaaaaa ttcctactat
    78241 aaacattatt ccggcagcta atagtgtctg ggctccgctt gctgttccag tttttggcaa
    78301 cttattagga ttgttagtag ttgatttact actgatattg tttttatcaa gaactgtagc
    78361 tgtaacatcc ttagttgaat cagatttttg tgaatgatct tctctttgta aatcctcttt
    78421 tctgtgactt tcatttaatt gactatggtt tacttgtggg ttatctttct ttttcgatac
    78481 atcaaaagta ggtttatttt cttcctcctt tttctcctct attttcttga atacaggttt
    78541 tataaaggta tcttttgata gattaataac atagccagcg tcttttttac cttcgaaacc
    78601 agaaattttc caaccatcaa attggtatcc tttttctaat tcacccttat aaataggtaa
    78661 aataaaatct tcttccgaca ctatcgttga actcatttct tttccatttt gaatggtcac
    78721 agttacccta tgaggtttta attcacttac ctctcccgta tctttattta aaatgaattc
    78781 ttttacggtt gtatttcttg caaaatcttt tacaacaatc ttaatgttta gtgtcttgtc
    78841 tgttatttgt ttaatatcat caaatgatgt atattctttt ccatttacat aaatatgttg
    78901 ttcttgaatc tcaccatcga atccattatt tcttttatca ttgatgttaa agactacaga
    78961 ttttccatca gcatattcga tactagtatt tcccttagga tcaatgttta cttcgggttt
    79021 aacattatca tataaaaact gatagtggac tccaactgct ttagcattca aatcactata
    79081 gccagtttga agataaacat ttccatccat atctgttacc ttatctggaa atccgtttgc
    79141 tttatagtct ttcattcccc agtccatgat gtcaccgtct ttaacattca gcttaatatt
    79201 aaaatctcta gtgttatcaa tgtgtaaatc tccgtagatt aaataattat ctacaaccga
    79261 ttcattaact ctcaattccc agttaaaacc acccttatca gaaatcttac ctcttaaata
    79321 aaattctgga tttcgtacat aaattttatt agatttagat ggattaaagt agttcttatc
    79381 cattgaaagg tttactggtt tggtatcaat aaataacatg gagccatctt cttttatagc
    79441 ttctacattg aacttatcct ctccagtgta ttctttatca tctttaccaa ataatacaag
    79501 tttagaagaa tctgtcacaa gatttccgtc tttatcgata gcttcccctt tatcgttcat
    79561 tttaaatgta aacacttgat accttataat gttaaagccg tccaaagccg acattaatac
    79621 agattgggta cttcttccat cttcaacatt tctactatca gcataaattg ttgtttctga
    79681 aagggctctt agattaggat tggccttttg tatttttgct atatcttcct tgctatagac
    79741 tccatttcct tctaacatat ccgtttttcc aggattatag gtagtcactt ttagtgcata
    79801 gccttttctt agaatgatat tatcctttaa cagatattgt tgtttttctg aatcagaata
    79861 gattttacca gattccattt tagttaaatt gtctggtttg ttttttgaaa gatctccttc
    79921 ccctaattct atgacattcc cataacttga tacataggga tattctgatt tagtttcctt
    79981 aattttttca ggcattctaa ttttaatttc agcttttttc tgatcattat ctttaacaaa
    80041 taatctcata tctcctgcaa aagctaatcc atccacaata tcattaatat tagcgtatag
    80101 atcaaatgtc atcgtttttg agtggaaatc atacttggtc gctttgattt ctatagattt
    80161 atagttattc ccataatata ccttggcatt tttagaaaca ttacttatct ttccaagaat
    80221 ttcaaagtgt ccatctttag acggacttag aacaccataa atttttgatt tgatttcgtc
    80281 aagtttctca gtttcatatt ctagatcagt cccatcatcg taggctatta tatttccttt
    80341 atcatcgtat ttataatcac gctctactgt tcttgttcca ccatttacaa agtcgtcttc
    80401 ttgcttatat ttctttttaa tgagtttctt taggtcttta ttttcaaagt ctctaattgt
    80461 tgaaatagtt ttatgaatat taaagagaga ttttccttcg atagactgat tatctactaa
    80521 aaggttattt tccacctcag ctgtctcttt gtttaggcta tcatctttaa cattttttaa
    80581 attcttaaat ttagattcag gaatttcgcc aagcttttgg tatttagatg aatcctgatc
    80641 aggatctact agataatagg aaatcatccc tttttcatca gcttgattag caaatttaat
    80701 cctatggatt ttggtaaagt tgcttgctcc atctagggcg attacttcga tgatttttcc
    80761 tcttagatct cctgctccgc taatttcata gatagtattc ccatctttat caagcttcct
    80821 atttcttcct tgaccctcac ctgcataagt tacttcaaga tttttctcaa cctctccatc
    80881 ttcattaaca agagcagctc ctgcatacca cacctcattt gcaatctcat caaatttttc
    80941 aggatgttct ttttgatctc tagcaaataa agtttcattc ttgtattgat cttttacctt
    81001 gtgataagta tcctttgtga ttagcttaat tttttcagga tttgaaaaat caaccgaaac
    81061 aatcttaggg gctgtgttat caatttttac aggaatatag gaaacctgcc atgggtaatc
    81121 tttagttaat ctatatttaa atttatagaa atattgacct tccgcaatcg gttcaaattg
    81181 tcctcgtatc ttagtagctg gatcttggtt atccttactt tctggggcat tttcttctct
    81241 acctcttggg ttatagatga gtccatccca tttcaagtca ccccaaactt ttagtttgga
    81301 tgatttgata cccttagcgt catttccctt agaatttaga attcctctta tgaagtgctc
    81361 tcttgataca actttaaggt ctttttggtt ttctccttct ttgttggtgt ttacaattga
    81421 aattagtcct tcttctgcac ttcttagaac aagtggagat ggagttagtc ctctttctag
    81481 ttgagcatct tgaggatttc catttgaatc taaaggataa atgttagcaa tcttagaacc
    81541 actagtggat cctgcatgaa caccttggtt gttaaaggca aataagtctg gatcttgatc
    81601 tagagatgtt ctatttttat cttttctatt ttggataact cctgctggat taaatttatc
    81661 tataccatgt tctccaccaa tccccttatt taaggttcct ggaatttttg gtttaccgtc
    81721 atcatcataa ccttccattg tttttgattt tgatccttct tcccaagccc atttatcaag
    81781 gattggttcg tggttccaat tcccagcaaa tcccatcagg ggcattgata aagatggttg
    81841 gaagtcggtt ttcttgccat tggagcttaa tgcttccatt tcttctactg actcaaaatg
    81901 aataaatgat tctacaaatt tatttttatt tttagcctcc ccaacattta taaccgcatt
    81961 taaatcaaag ctagaatttg cccctatagt gaaagtgtca tgctcaaatg taatatttgc
    82021 ccctttgact ttttctggat gaatttctgg aacaatttgc ttaccatctg gagatttttc
    82081 atctttatat gtttcatcca gttttagtct gtcagttaga gaatctgtag ttaccgctga
    82141 tgctgaaact ttaaaggtta aaggcctgtt ggatgtattg tgaagcttaa ttgtaaagta
    82201 ttttttatca ccttttattt ctttaagaga aatggaacca tatgaattta ccaaaccttt
    82261 agaatccgtg tttttgaaag tcgctacaac ttcatttctc aaagcgttgg ccacattaat
    82321 tagccccgcc ccctgctgtc taggtgatgc aaagtattga cttttttctt tccaagaagt
    82381 tgcatccatc ataggtcttg cagtattttg tagggctatt tttgtaagac ttgtaaggtc
    82441 tattttatca tcacctttaa gattttttaa tacgggtttt tcaagcattt ccttcaattt
    82501 tggtcgaatc aaaacagtag aagctgctac gattggagtc gccatactag ttccggacat
    82561 atagccataa gttgatttgc cattaataac attaagcgtg gatttaatat ttttaccagg
    82621 tgctgaaaca tcgggtttta aaagtaaatc tattcttggc ccccaagatg tggatcctgc
    82681 tggaacgatg atatcttctt tatagagttc tttgtctgtg tcaggtgcaa acttaaagtc
    82741 aatctctttt tcgtcaccta cattcggttt gttggaatta aaactttcca tatcaattgg
    82801 atagtattgc tccaatttat ctttaaaatc ttctttatta tttcttttga cttcagtttt
    82861 tttatcagga ttaatcatgt tccatagctt tacaccatca tctcctgaaa ttgaaaacac
    82921 ttgactttta gtaccttcat ccgcttcata tcccatagct ggaagctctg tccaattatc
    82981 tctattgtag taatttacag tatttacaac cataatggcg cgtgcaccct tatccatagc
    83041 ttttttaaaa gcatttttta aatcctttgt ataaattcta tccattactg caattttgcc
    83101 cctaagatcc aaacctatca aatcttggtc ttgccccttg cctatatata caaattttaa
    83161 tttactagga gcttttgttc catcttcatt tgttgtgatt ttattcttat cgaaaaaggc
    83221 ccctatattt ctgtatttaa aactttgtcc tccaatgtta accttatcaa actcaactgt
    83281 ttgattttta gcagaagcga ccgctatcgc atcttcatgt gctgcagttc gtgttacatt
    83341 tccagtgtcg gtcattttca gatgattatt tgctactaaa tcccatgaag aacttgaagc
    83401 agaagtcgca tagttacccg tagcgacaac cattggaatg cctgcttttc ttaatgcccg
    83461 aatagcttgc caatatttct cacctacaag acctgttcct gtaaaaccag atgataccga
    83521 aacaacatca acgttgtgtt tgatagaatc ttcaatagca tgaaacattg tttcatcacc
    83581 cgcaaaccca gatcctgcgt cagaatacat tttgtaagag aaaatttgtg cattaggtgc
    83641 aattccatct atgccgttaa agtttttgat atcttgttca gtatcatttc cagcaagaat
    83701 ccctgcaata tgcatcccat gtgggtcaaa ataatctctt ccatcatcat atttttctac
    83761 agtgattttg ccaccattat aataattgaa cgcatgaggg attttatcac tcaaccaata
    83821 atttttatca gttcctttta agtcttcttt tttaaatctc attgaggctt tggcatcatc
    83881 atcgattctc atagccttat gtctataatc tgttccagta tcgatatttg aaatgaccat
    83941 acctctacca tcaaaatttt tcccaaacgg agcattgata gactttaggt aatcaatagc
    84001 ttcctcaact ccaatttcct ttctggcatg attcatcatg ggttggactt tttgtgccct
    84061 ttcaaccgat gaaatacctt ctatttgttt aattttgtcc aagttatctg gagttgtttc
    84121 tatggcacta ccgttaaaaa ttctatcata agtatataaa acttttgtat tcttaagact
    84181 ggatagttgc ttgattgctt tttctccaga ttctttatct ttaaattcag caatatagac
    84241 aactttatct tcttttttgg gattttctgt gtttttattc acaaatgagt ccgtataatc
    84301 tccttgggat tgattggaat tttcttcttt gatttttgct tcttcattgc tagtgttatt
    84361 gtctatcaca ggatttttac taacaacttc tttttcctta atgactgctg ttttcttctc
    84421 tttaaaatcc tgtgaagttt ccatagcact atagatattt tcatgtttct ctttattttc
    84481 tgctactttt tctttatcag agatgcttaa agcatcttca gagttagatg tgtctgctaa
    84541 gactacctca ttaggggcat aggctgctaa aataactgca gctgtggtta atgacaatac
    84601 tgtacttttt ttcattttaa ttccttacat atttatttaa actccaatag ataataaact
    84661 ttaactttgc tagcctttgt tataaaaagt tttactaagt attatctagg aaatagagta
    84721 gtacatttat atataattgt tatctctcca taaaaacagt atatcattta aaaaaattta
    84781 attcaagaaa aattaacatg cattaattta ttttttagca cacgttaaaa aataagatta
    84841 gtactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct caaaacactg
    84901 ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acgcacggca aggcgacgtt
    84961 gacgtggttt gaagagattt tctaagagta taagtccaaa actttcgtta accgggatac
    85021 attataagca cattcatacc atcaaaaata gtagcaataa acttgaacaa ctaccagaaa
    85081 cacgaaaaca ggcataattg atgaaatatc agcgctatta aacaatataa ataaccgcta
    85141 agaataaggc ttaacggtta tcttctacct atctattttt tcaactcctc agtcgtttat
    85201 ctacctataa cctaggcttt acgagtgcct tgctctacca actgagctaa atcggcgatt
    85261 acacttacag tatagcactc tgagaataga tgtcaaataa tattattcaa gctttttaat
    85321 caaaatctga caaggatttt gcggattcca tagttgaaga aaaatctcta actttttaaa
    85381 gccaaaacct cgataaaagt catttgttcg atcataatct ttattagaac cttctgccac
    85441 tgttttgacc tgcagataac caactttttt acgagcttca ctctctaaag tagcaaacaa
    85501 ttggctccca atttttctac cttgataagc ttttttacgc cgagacaatc aatctctgca
    85561 caatcttcac tcgaatagga taagcttaca aatccagtca aatcactctc ctgataggcg
    85621 gtccaaactt gcagtgtcgt ggttccttct atataggctt gtgtgctttc tgggattcca
    85681 aaccattctg gcaaatcctt caaaacctca gcgacaactg cctttttttg attttcatcc
    85741 ttgacttctt caattacaaa catcataagt tcctttcttg attttagtct tactttagct
    85801 tttacgaacc cgcactttcg taggaatcta agcccttatc ccaaagttta agggaaataa
    85861 caaagaaaat cagagaaatc aacatcaaac ctcctacgtt aaagaacaca tccttttcct
    85921 gtaagaaata gctagctgga tagtaggctg taaaggcgaa aggcacgata aagctaatca
    85981 accaacgaag aagagaattg taaatagaaa tcggatactt agcaaagtca ttgaacatat
    86041 agaagatgta aatcatggcg cctgactgct tagtccaaaa ggcgatactg gctgttgcga
    86101 ttttaagaga agtataaatc aaggtcgcaa aaggaataca aactaggaaa agcagaaatt
    86161 ttggaagagt ccaaacaatg ctggtcactg ttgttcccaa taaaatacca ccgactaaga
    86221 gttcacccaa ggcatcaatc tgaaaggttt caactaggat gtgaaagaga ggattgatgg
    86281 gacgagtcag atacttgtca aactcccctt ttcggactag gcgttgccct agtgcccaga
    86341 gattgtcaaa aaagagatgg tccattccct tgggaatcaa ggaaaatcca taaatgaaag
    86401 ctatctcttg aaaggtccag ccttctagga atggaatatg ttgaaagatg acattgagaa
    86461 acaagagatt caagccttga gccagaaaga ctcccaagac accaaccaca aaatccacct
    86521 tatattccat gatttgtttg atgtattgtc tgataaaaat cagatgcatt cgttgatatt
    86581 ttttcatact aacctccttg aatggtgata aaggactgga cccgtttcca aatcaactga
    86641 gacaatccca ccatcactaa gagccagaag aactgcaaaa ggagtgcctg aagaatctga
    86701 ctggcatcgt attttccaac aatgatcata actggagtat aaatcaagga tgaaaaaggc
    86761 aaaaaggaga gaatatctga aacaaccttt ggaaagaatg ccaagggaat caaactcccc
    86821 gacataaaag ccactatgga agtcttaagt aggttggaac cccaaagatt tttaaacaca
    86881 aaggctgaaa atccaaagca aatattaaag aaaaagttaa tcagataggc gagcgttaag
    86941 ctaaaaagat aaatgacagt taatcctagc acctctacaa taccttgacc cgatatgatt
    87001 ttcatcaaga caatgacact taaaaatgga aggccaacgc tgataaaaat caaccacttg
    87061 gaaccaagct cggtgaaaag ataggaggcc gcaaaatgca ctggtcgcaa caaacgcatg
    87121 ataatggagc catccttgac ctcctcccca atcataaagg acgaatcgga tctagtcaga
    87181 agattggtca caaaactcat gatgatgtag agggtgatat ccgccatact gaagccctga
    87241 atcaaagact cttgcgaaga atcaaagaca gccttccaga gataaaaggc cacaaaagcc
    87301 cccatgacat cgccaatccg atagagaata aagttgactc ggtaagtaat caactcctga
    87361 acccctgcat tgataaaggg tttataacgt ctccacaatt tgatcatcct agagctcctt
    87421 tcggtagaag cgacggataa tatcctcaat atccgtatcc accatcttca aatcgcggat
    87481 ttcaaaatca gacagggttt gcttgataat gtcagctgac tggtagcgag aactatcaaa
    87541 ttcaatgttg aggctgtttc cttgtctatc aatggtcata tcagacagac cttcatagtg
    87601 agagacgaga tgactttgac ctggtagcag ttcaaaagag agagtcttca tcttaccaaa
    87661 ggtctccttg agttggctca ctgttccatc aaaaatctct tgccccttgt caatcatgaa
    87721 aatccgatca caaagttgct caatatcact caaatcgtga gtggtcaaaa gaatggtagt
    87781 ttcttcctct tgattgatct gagtaattgc ccgacgaata ttatccttaa ccgaaacgtc
    87841 caaaccaatg gtcggctcat ctaaaaaaag aaccttggga ttgtggagca aggaggccgc
    87901 aatatccgcc cgcatccgtt gtcccagtga aagagtccgc acgggatcct tgataaagtc
    87961 cttcaaatcc aagacttcat tcaaaaagtc catacgctta tgaaagagcg agtctggcac
    88021 atcataaatc tcttttaaga cagtgtaggt ctcttgcaga gccaaatccc accatagctg
    88081 ggtgcgttgt ccaaagacta cgccaatatc tttgacataa tcttgccgat tgtcctgggg
    88141 aatcttgccg ttaatccgac aaaaaccaga tgttggtttc aaaattcctg tcagcatttt
    88201 aatggttgtc gacttcccag caccatttgc cccgataaat cctaaaatct gcccttttgg
    88261 aacctcaaag gtcaaatcct tgaccgcttc aaaggtctgc ttttcaggat gaataaagga
    88321 gcgcaaagcc cccttcaagc ccggttcctt aacaatcttc acaaaatgtt tctgaagatg
    88381 ttccacttct atcattgcca tatctatctc cctatcataa ggaatagcaa cattgtgttt
    88441 ttaactacaa atattctaaa tccttacttt ctacaccttc tacattttat tactacagaa
    88501 ggctttatac caacctatta tagtccaata aaaaacagaa tgcaagcgtt tgcctatgga
    88561 ttgtgaaatt aggatttctc tcatgaaata atacttttaa tcaaaaattc tgtttaatag
    88621 tttaaattac caacctactc atcttctcac cagagggcgg tattaacttt gatcataaaa
    88681 tcggatactc cctctatcca gaaaatatgc tcagaatgat tgtctctaaa caatacctgc
    88741 tcttttacct cattcatgaa aaagaagtcc ataccctgag aattatcaac tcacgcaccg
    88801 actacctaaa ccaactcgac cacctctttc gtacatgtag gaaactattt tcctcacaaa
    88861 taatctcatt ataaaatcca ataaattttt ttagctcact tgaatatttt ctttgtatcg
    88921 ttttatcagc ttcaatctga tctagacttg ttaccttgga acgacttgaa ataacctttg
    88981 taaaataaca cttaaggctt tcatcatctc gtataaattt ttcaatagtg atataaaaag
    89041 ctttcatatt ctgtttgtaa tcagatatta attgattaat tttatcattc tgatgaagat
    89101 tcgataccat aatatatagc ggattgaaat aagatgagaa caaatcgatt gggaaagtaa
    89161 aattaatttc tataaatatt ttagcaattg tttcgtacta ttttagattc agtctactat
    89221 acataaacta acctcctcat tattagcaag gcttctactg attataacct aattcttaga
    89281 ctacttcaag actaactgtc caataataat ctacagataa atcatccact cttaatcaaa
    89341 ttttattcaa tccatctact cattcccaaa aggttgctgt ataatgcaag acatttttct
    89401 tactgctttt acttttcctt accctcaatt tagtgagcta ataaattatt cttcttcaaa
    89461 aggttgagat ttatctagta actctaaaac attaatggta ggtagcaaca ttgcttcact
    89521 gctatcaatt gccgaaacta ttgaaacaat agaacgtaaa taaggacaaa gaatagcagt
    89581 accatttacg tatagaatat cggtgatatt ttcatctata tttatttcaa aatatcctat
    89641 tacagttaca gatatttttt catggcatct ttgtcaacta aagaaacact aagttttacg
    89701 gctccatgac tataatcatc tgtatgacca accttaacta tgggatataa tatatcgaag
    89761 gtaaatgtga acaaactgat tagggaattt aaaccaactt ctaacaatgt gttatactca
    89821 atgaaaacca aagagcaaac taggaaacta gccgcaggtt gctcaaaaca ctgttttgaa
    89881 gttgtagatg gaactgacgt agtcagctca aaacactgtt ttgaggttgt gaatggaact
    89941 gacgtagtca gttcaaaaca ctgttttgag gttgtggatg gaactgacgt agtcagctca
    90001 aaacactgtt ttgaggttgt ggatagaact gacaaagtca gctcaaaaca ctgttttgag
    90061 gttgtggata gaactgacga agtcagtaac catacgcacg gcaaggcgac gttgacgtgg
    90121 tttgaagaga ttttcgaaga gtattagaaa gctcgatgga ctattccaga ttcattccac
    90181 tagatttcga aatcgagtag gggataatct ctagcccctc tcacaccacc gtacgtgccg
    90241 ttcggcatac ggcggttcaa ctaactttta acgcatgtcg ttcaaggtaa taatccaaac
    90301 acgaaaccag tccacgtttt tcaaggactg gttttgatat agcacgttta agtaccgact
    90361 tctgagctac tatagtagat tgaaactaga atagtacacc tctacttcta aaacattgtt
    90421 agaaatcgat ttgactgtcc tgaacgattc gtcctattct tatttcattt tactataatt
    90481 gatagtggtc gccccagcca gataccttat ccgctatata ggccttatta tcacgttcct
    90541 gttcgtagag ccacgatttc gctatccctt cctctgacga ttcttatttc cagcgtcaga
    90601 cttaaaacgg tctatcccca gaccgtttta atccgctacc tcacgatagt cagacttggg
    90661 aatcgctatt gggttcacca gtagtaggtg cccaccgagg actcacacct cagatatacg
    90721 acatgcccgt cgtacatcaa aaaaagttga gacatagcgt cttcaacttt tttacattac
    90781 tttaactact gattaaagtg agtttacgtc aactttgata ccaacacctt gagtagttgt
    90841 gatagtcaag tttgttacgt aagttccttt agctgtagct ggttttgctt tttggattgt
    90901 ttcgttgaaa gctttaaagt tttcaaccaa tttttcagct tcaaatgata ctttaccgat
    90961 gattgcttga acgttacctg cacggtcagc acggtaagtg attttaccac ctttagactc
    91021 ttcaactgct ttagcaacat ccattgttac agtaccagtt ttagggtttg gcatcaagtt
    91081 acgtggtcca aggacacgtc caagacgtcc aacaagagcc atcatatcag gtgtagcgat
    91141 aactacgtcg aagtccaacc aaccgtcgtt gattttagca acaaggtcat cttcaccaac
    91201 aaagtctgca ccagcagctt ttgcttcttc agcttttgca ccacgtgcga aaacaagaac
    91261 acgtgaagtt ttaccagtac cgtttggcaa taccattgct ccacggattt gttggtcagc
    91321 ttttttaacg tcgatgttca agttgtaagc aacttctaca gttgcgtcaa attttgcaaa
    91381 gttagtttct tttgcaagag ctacagcttc ttctacgctg tatgcttttg tgctgtcgat
    91441 tttctcaaga gcagcacgaa gttgtttgct ttttttagcc attttctatt ctccttgtaa
    91501 gtggttcaat cgattttcat ctcccacgtc acttctcgaa atgatgaagt cttgcgggtt
    91561 ttcagtctac tatttttctc ctcctacggc cttaagctcc cttgctgtac ccaagtacaa
    91621 gcctcagtca cttgcctagt atgaaaagca actaatagac tgctgtgaga ttttctactg
    91681 tgttattgat tagtcaacaa cagtgaatcc catagaacga gcagtacctt cgatcatacg
    91741 cattgcagac tctacgtttg ctgcgttcaa atctggcatc ttagtttctg caatttcttg
    91801 tacttgtgca cgagtaactg tagcaacttt agttttatta ggtgtacctg atcctttttc
    91861 aacacctgca gcttttttca aaagaacagc agctggtggt gttttcgtaa cgaaagtaaa
    91921 tgatttatct tcgtaaactg agataacaac tggaatgatc ataccagctt ggtcagctgt
    91981 acgagcgttg aactcttttg tgaatcccat gatgttgata ccagcttgac caagagcagg
    92041 tccaaccggt ggagctggtg tagctttacc agcagggatt tgcaatttta caagtttttc
    92101 gactttttta gccattttta aatcctcctt tgtggttttg gcggtaatta gagattttta
    92161 cctcccacaa gtatgttttt cacataccca tccattatac actatttatc tggaattgca
    92221 agagaaaagt ttatttttta tactcaatga aaatcaaaga gcaaactagg aagctagcca
    92281 caggctgctc aaagtacagc tttgaggttg cagataaaac tgacgaagtc agctcaaaac
    92341 actgttttga ggttgtgaat agaaccgacg cagtcagtag gtaaggcgac gctgacgtgg
    92401 tttgaagaga ttttcgaaga gtattaatcg acgtagtctc cgccttcaaa gccatagtat
    92461 tcttccaaac tgagaccact tgcagcaatt tctttagctt cttttcctac ataacgcagg
    92521 tgccattcct cagccatata gcctgtttcc ttttccttgc ctttgagata acggacaaca
    92581 aagccataat cagctgcatg atccaagagc cattgggctg ctttttcttc tgtcaccaaa
    92641 tcaccatcag tcccaatcac atcaaaggcc aagcctgtct ggtgttcgct atagccagga
    92701 cgggcagagt aacggtcagc tgctgccttt ccatcttggt tgacataatc ttgatagagc
    92761 ttggtctgag tttcataact tctaaaacca ctgtaatgat cactaatagg gaaacctgcc
    92821 tcttgcatcg ctttgatgag tttgaccaac tcagccttgg ctgttggatt ttccccggga
    92881 ttatagtctt tcgacaaagg ataatgttta ttggctacga tgatttcgtc gtattttcct
    92941 tggatgctgt agtaatcacc tttattgacc acttctgctt ttttctgggc agccccttga
    93001 gacttactgc cgactgtccc atcagctttg gctgtctgtt ctgtcttagc tgtgccatct
    93061 tcattttttg ctttttcttg tgaacaagct gctagactca aggctagcaa ggctgtcacg
    93121 acaaggtatc ttttcttcat ttctactcct ttatttctaa tagtttatct acttctgatg
    93181 ataaacgttt gactaatctt ttaatagact tcctgcaaaa ctagaatcct agttcatgat
    93241 tgataatacc agcaatcaaa ttcattcgta atccgaagcg tttacgatga tttcgatagg
    93301 ttgttgaaaa cattttaaac gtttttactt tggcaaggat gttctcaacc ttgcttctat
    93361 ccttagatag cgcatggtta taggctttat cttcagctat tagcggcttg agtttgctgg
    93421 atttacgtgg agtttgtgct tgaggatata tcttcatgag cccttgataa tcactgtcag
    93481 ccaagatttt accagcttgt ccgatatttc tgcaactcat tttgaacaac ttcatatcat
    93541 ggcaatagaa acaattctcc cttgacttgt gacaatcgct tgagccttca tagcgtgaaa
    93601 tttcttttta ccagaatcat tcgctaattg ttttttaggg cgattgattt gtacttccgt
    93661 cgcatcaatc attaccgtgt cctcagaact gagaggagtt cttgaaatcg taacaccact
    93721 ttgaacaaga gttacttcaa cccatcggct ccgacggatt aagttgcttt cgtggatacc
    93781 aaaatcagcc gcaatttctt cataagttcg atattctcgc acatattgaa gagtggccat
    93841 aagaaggtct tctaggctta atttaggttt tcgtccacct tttgcgtgtt taagttgata
    93901 agctgttttt aatacagcta acatctcttc aaaagtcgtg cgttgaacac caacaagacg
    93961 cttaaatcgt gcatcggtta gttgtttact tgcttcatca ttcatagaac tactatacca
    94021 tattttattt cgcaggaagt ctgatctcat ccggttttgc ttgacgggtt tctgcggtta
    94081 tttcttcaaa agggacccac cagactggcc cacagccctt gagaccgtgg ccattcatat
    94141 cacctcttcg tctagggaaa aggtgccagt ggagatgggc atcgccattt cctagaagtt
    94201 caatattcat tttctcagca gtaaaggcct tggcaactgc ctcttggact aaactcattt
    94261 cttctagaaa atggagtctt gtgtcctttt ctaaaatggt gcaattccgt gacatgttcc
    94321 ttggctaaaa agagactata gcttgcaaaa tactgatggt ctccaatcac aagatagcct
    94381 gtttccaact ctttgacaaa gtagggattt tctcccttct tgatgagctc aattctctgg
    94441 caaataaggc acatatcaat ctactaaatt gcttctaaga taggcatcga ccattcgttc
    94501 tgttgcgacc accgagtcaa tatgagtgcg ctcataagaa tgactagact cgatacccgc
    94561 accaagaagg gcatgcttga cctctgcccc tgcagacata gccgctgaag catccgaacc
    94621 ataaaatgga tagatgtcca gcttaaaagg aatatcttgc tctttagcca aggcaaccaa
    94681 gtgttgacgg aagtcatagt gataaggacc tgaagcatcc ttgacacaga tagatactgt
    94741 gtactcatct gtctgctggt catctcccat agctcccata tccacagcca gatattctac
    94801 tacctgagca ggaatgttag aattagcacc atgtcctact tcttcaaaaa ctgaaaaacc
    94861 aaaatgagtt gttactggca attcaatctt ctctttctta taaatacgaa gcaggttgag
    94921 caaaatcgct gcgctgacct tatcatccaa atgacgagac ttgataaaac ctgtatcagt
    94981 cacaacagtt cgtggatcga agctgataaa atcaccgacc tcaatcccaa gagcacgagt
    95041 ttctttttca ttgcttactt ttacatccaa acgcacttcc atattgtcct gcgtgcgttc
    95101 tgcagttcct gcatccttgt agacatggca agaagtttgg tggatgagga tggttcctga
    95161 taccttttga cctgtgctag ccacatgaac ggtacagttt tcaccttcaa tcatgttcca
    95221 aggaaaacca ccgatacggt ccaatttaag acgaccatct ggtttgacag cacgaacaat
    95281 agcacccagc gtgtccacat gggcagtcac atagcgatgt tgctcatcat tttgaccttt
    95341 gatggtcaca ttgacaccac ccttggctgt gcgaactggc tggtaaccaa aaccttctag
    95401 agtcttgact aaataattcg aaatttcacg agtgaagccc gttggcgatg cgatggctgt
    95461 cagttctttg atatattcta ctgtttgatt catttcttca cctctttcgc tacctattat
    95521 aacacattta tcatcggata aaaaaagaaa atcactcctg tagacttggc tacaaaagtg
    95581 atttaagtga ttattccatt tcaaaaacat cgctttcttg cttgtttggt agaaccaatg
    95641 agagcaagat tccaacaatg gctggcacca accatgggag agatgccttg gcaaaaggaa
    95701 gaacgctaac aagatttgca agaaactcaa ccttaaacga gcttcctagt acgcttgcaa
    95761 tggcaataac tgtaaccaca gcaattgtca actgcatacc tggttttgaa agggcaacaa
    95821 atttgttgac aatgacaatc ataacgatag caatcgtgat tgggtacaag ataaccagta
    95881 ctggaattga gtacttgata atcgcatcaa gacccaaatt ggcaatagca aatccaatca
    95941 aggtaaaggc tgtcgcataa accttgtagc tgatttgtgg gaagcgctca ttaaagaact
    96001 cagctgttga cacaatcaaa ccaacagtcg ttgtgaagca ggttacggta accatagctg
    96061 caaggaagag ttgagctgtt gagccaaaga tttcttgagt ggcttgtgac aagatgtaaa
    96121 cacctggtgt tccacccttc atcgcttcag ctggtactgg gaaatgattt ccaagaaaac
    96181 ctaaaccgat gtaaagagcg ctgaaggcaa gggcaacaac gataccaaca acccaaatag
    96241 ttgaaatgta ttctttctta cttgaaaatc caagttgttt caaggtttga actgcgatta
    96301 cgctaaaggc cactgaggca agggcgtcca aggtattgta accttctagg aaacctgtac
    96361 caaaggcaga agcttgataa gcagctgaag cagcttgagg acttgttcca ccatatttga
    96421 tagctcccag aacgaccaag ataacaatca aaattgcaaa gactggcgtt aaaatacgtc
    96481 caatgcggtc taagattttt gatggattaa gcgaaatcaa ataggctgcc gcaaaataca
    96541 gaaccgtaaa tacaatcaag ccaagtcctt tatttgcatc cgacaaaagg gggctaatcc
    96601 ctacttcgta agctgttgta gcagtacgtg gggtagcaaa gaatggaccg attgacaagt
    96661 aaagaactga gaggtaaaga gtcgcaaacc aaggcgctat cttcgttgaa atctcgtaga
    96721 tatatccttt aggatttagc gttccaataa taagggtcaa gacggcgata ccaacgcctg
    96781 aaaagacaaa acctgcgatg gcaggaagaa aatgttctcc agatagagca cctagagaag
    96841 gcggaaaaat caagttcccc gcaccaaaaa atattccaaa caggagcaaa cctgttaggg
    96901 tacctttttt agccataaaa atctccttca tatttataaa atactgacct agtataccac
    96961 gattaggagt ctgaaaaaag catcacgagg caaatattaa atgttttcaa ttttcttaaa
    97021 aataagaatt atctaaaaat aaaactctcc tacccagtcc acaccaagta ggagaaatgc
    97081 aaaattttaa agttcttcaa aggctaacat gccaccctgg acattgataa cattataacc
    97141 ttgttctaat aggaattggc aagcacgcgc cgatctcatt ccagatttgc aaataatata
    97201 atgcaagcga tctttgtcca attaatcata actatcagcc aattgactaa gcggtaggtt
    97261 gtgggcacct tctaaatgaa gagctgcaaa ctcatccact tctctcacat ccactaaaga
    97321 aagctggtcg ttttggtaaa gctggtaaaa tgcgtcaaag gctatttctt tcattctttt
    97381 tcttctaata ctcttcgaaa atctcttcaa accacgtcag cgtcgcctta ccgtgcgtat
    97441 gttaccgact tcgtcagttt tatctgcaac ttcaaagctg tactttgagc agcctacgac
    97501 tagcttccta gtttgctctt tgattttcat tgactataaa atggttttaa ttcttttttt
    97561 caaatctggc actacttctg cctcaaacca aggatttttg gccatccaga tttgatttcg
    97621 tggtgatggg tgaactagcg gaaaataggc tggcagatag tctttatagt gtttcaccct
    97681 ctccgttacc ttcccactga ttttctcctg taaatagtag gcttgggcat attgcccaat
    97741 caagagggtt aactgaatat caggcaattc ctgtaagagc tgcggatgcc atttttctgc
    97801 aaaacctgta cgaggcggaa gatcacccga cttgccatgt cctggaaagt agaaatccat
    97861 aggcaaaaca gcaaaataac ctgaattgta aaaggtatct tcatccacac ctagccagtc
    97921 ccgcaagcgg tcaccacttt tatctttcca gtaaaggcct gcttcttgag ttttaagtcc
    97981 cggagcctga ccgatgatat tgatgcgagc agtttttggc gctgcaaaga gaggctcaat
    98041 gccacgctct gtatagctgg cattctgcga atccgccatg atagcctgtt tgattctttc
    98101 gatttgagac atctactttc cctccaaaaa gaagtccaag cataagatct cagacttcta
    98161 tcgttttatt tgatcaattc gtaaatagct tcggcataaa ttgctgctgc tcggaagaga
    98221 tcgtccaagg caataaattc attggcttgg tgcatggtat caattgagtc tgggaacata
    98281 gcaccatagg caactccgcg ctctaacaag cgaccaaagg ttccaccacc gatgacttgt
    98341 tcatgacctt gtaggcctgt ttgtttttca tagacattca acaaggtttg cacaagtgga
    98401 tcttccattg gcacatagtg aggggtatga ccatgttctg atagactgac agaagcaact
    98461 ggcaagtttt ctaggattga cttgatttgt tctggacttg ttccttttgg atagcggatg
    98521 ttaagggcaa tggtattatc agcacttgtt tcatcgaagc ggaagacgcc ggcattcata
    98581 gaaagagcac ccatcttttc atccacatga gcaatcttaa gattttcacc ctcatgatcg
    98641 ttcaagagaa ttttacctgc gatgtcaagg tagtctttgg ctggaccagc aaagccaaac
    98701 tggctgagga agagggcaag gtaagttgcg ccattgacac ctgaagcagg catagcaccg
    98761 tgggctgatt taccaatgat cgtcaccttg tatttgccag cttcttcttg gagttctcct
    98821 ctaagtttgt gttctgcaac aaaggcatct agtttagctt gcaagtcagc caaatcacct
    98881 gaaacgactg ctgttgctga ttctggtacc atattttcac gtaaaccacc tgtaaagctg
    98941 tgaagacggg cagcacctgt attttctcct gcaaagtgga ggtattccgt gatatttcct
    99001 ttttcaccat tgatgattgg aaattcagca tctggtgaga aaccgaaatc tggtttggca
    99061 agtcctacgt gctcaaagta gtagtccatg tctgcccagc ctgattcttc gtctgttcca
    99121 acgatgaagc gaactttctt agaagttgga agacccaatt ctttgatgat tttcaaacca
    99181 tagtaacaag ctgttgtagg acccttatcg tccgaagccc cgcgcgcata aaggcgacca
    99241 tctttgatag ttggtgtgta aggatctgta tcccaaccgc taccagctgg aaccacgtcc
    99301 atatgggcaa agattccgag aacttcttct ccatcaccaa actcaaaatg tcctgcatag
    99361 ttatcaacat ttttagttgg ataaccatca cggtctgcga tttcaaggaa tttttccaag
    99421 gcttttactg gaccaggtcc aaatggatgt tgggcatcag ccttgctatc atcacgttct
    99481 gagttgattt ccaaaaggct aaacaagtca gccaagaggt cttctttgcg tttttctact
    99541 tctgctgtaa aatcaattgc tatcattttt tcttcttcct atcttttttc gatgatttca
    99601 tctactggca agcggtagct tggttccaat ttgtcgtctg tgtaacccac tgtgatcaag
    99661 agttctgggc ggaaacggtc ttcgatttcc aaaacttcat taacttttga tttgtcaaaa
    99721 ccaaggataa tattggaacc aattccttgg tctgtaagag cgagaaccaa gttcatagca
    99781 accaaacctg cattgagtgc taggtagtcg ctgacttgtt gttcattgta gcgtgcaaat
    99841 tcagctggca aatttttcat gaagtattga agttgttctt ctgagaaatt gttagcacca
    99901 ccaactcggg caatcttacg agcgcgtttg gcaaggtctg tatctgtaaa tagggcaatg
    99961 gttacaggtg ctgatgatac ctgctcaaag tttgaaccat aagccaactt tgccagttca
   100021 gcatttttct cacgaacaac tacaaatttc caaggctggc tgttgtgggc gcttggcgcc
   100081 aaggttgcaa tttcgatagc cgtacgcaca tcttttggat caacaggctt atcagtgaaa
   100141 tgcttggtcg catgacgttt tttatttaat tcaagaaatt tcataatcga tttccttttc
   100201 taattctact gcttccattc taccataatt tgaaagagct tgcagggatt tttcatgatt
   100261 aagtttttct atcacagaca taaaagatat atattggttt atcaggaaag tttctgataa
   100321 actagcaagt actttacatt tgaatggaga cagtatgaaa aaatttagcc tattactagc
   100381 tatcctacca tttttggttg cctgtgggaa tcaagctaca cccaaagaga ctagcgctca
   100441 aaagacaatc gtccttgcta cagctggcga cgtgccacca tttgactacg aagataaagg
   100501 caatctgaca ggcttcgata tcgaagttct aaaggcagta gatgaaaaac tcagcgacta
   100561 cgagattcaa tttcaaagaa ccgcctggga aagtatcttc ccaggacttg attctggtca
   100621 ctatcaggct gcggccaata atttgagtta cacaaaagag cgtgctgaaa aataccttta
   100681 ctcgcttccg atttccaaca atcccctcgt ccttgtcagc aacaagaaaa atcctttgac
   100741 ttctcttgac cagatcgctg gtaaaacaac acaagaggat accggaactt ctaacgctca
   100801 attcatcaat aactggaatc agaaacacac tgataatccc gctacaattg atttttctgg
   100861 tgaggatatt ggtaaacgaa tcctagacct tgctaacgga gagtttgatt tcctcgtttt
   100921 tgacaagata tccgttcaaa agattatcaa ggaccgtggt ttagacctct cagtcgttga
   100981 tttaccttct gcagatagcc ccagcaatta tatcattttc tcaagcgacc aaaaagagtt
   101041 taaagagcaa tttgataaag cgctcaaaga actctatcaa gacggaaccc ttgaaaaact
   101101 cagcaatacc tatctaggtg gttcttacct cccagatcaa tctcagttac aataatactc
   101161 ttcgaaaatc tcttcaaacc acgtcagctt tatctgcaac ctcaaagctg tgctttgagc
   101221 aacctacggc tagcttccta gtttgctctt tgattttcat tgagtataag atatactaaa
   101281 agcgattgga ccagccaatc gcttttttag tttgcattgg ttattttagg aaactcttac
   101341 aaaaaatcaa aataatcttt cacatcctct acatacccat gcttttctat taagcttgct
   101401 aaaagttcca gattgtgtcc ctgatagtta tcttcacgac gtagttcttc atacatttcg
   101461 ataaagggaa gccccttgga cttggccaat tctaactcag cctcgtaatc ataagcaact
   101521 ttacgaaatt ggatattgac caattccccg tcttcaactt ctatcacggc atactgggca
   101581 cggtgatttt ttaacgcctc ccaattaaaa tagggcatgc caatcgaccc tggattgatg
   101641 atttgttgcc cttgacttcc ataacgaagc aactgcttgt gaacatgacc ataaactgcc
   101701 acgtccgttt ccgcatctag cagttggtca aatttctctg tatcattctc aactagcaag
   101761 tcaccaccat agtttttgtc aggtaaatta tgagagatag aaaagtgcaa tccgtcaatt
   101821 tctttctttt ccagcaaagg caagcttcgt agccagacaa tcgttgcagg atccattcgc
   101881 tccatcaaaa actgggtcat gcgcattgac tggatttctt tcggatattc caaaccatat
   101941 tcgccatcca agacctcaag gacacgatca tcccaattgc ctcgaacact tgctgtgata
   102001 ggaaggtcct ttagcagggc gactaagtca tttgcgcctg gaccaggaag aaaaatatct
   102061 cccagaagcc agtattcact gactccttga tttttagcat ctgcaatcac tgcttctagc
   102121 gccgtcacat tgccatgaat atctgataaa attgcgattt tatggttcat tgtggtttcc
   102181 ttccgtttgg taatctactc tttcttctgc tacttgaggc aaggcttctc cctgcgggtt
   102241 caactttctt tgcacagcct ctgcaacgac tctaggtacc ccaacttcga caatctcatc
   102301 cacactggct tccttgattt tggtcaaaga cttgaaatgc ttcataagat tctgcttgcg
   102361 tttaggtccc agaccgtcaa tcccatccaa ttgagatgag aaagaatttt tggagcgcag
   102421 ttggcggtgg aaagtgatag caaagcggtg cacctcatct tggatgcgtt ggaggaggaa
   102481 aaattcctga gaattgcgag acaagtccac cacctcaagc ggatctccaa agagcaattc
   102541 atgggtttgg tgcttatcat tcttttgcag cccagcaatt ggaatatcca agcccagttc
   102601 ctcttggata acctgcttag cgatattgac ttgaccttgc cccccatcaa tcacaatcaa
   102661 atctggagga gtcaaagcct cacgctgtac tcgaccatag cgtctgcgaa tgacctctct
   102721 catgctggca tagtcgtctg gtccaacaac cgtttttatc ttgtacttac ggtaatcctt
   102781 cttactcggt ttaccgttga caaagatcac catagccgaa acagggctag ttcccatgat
   102841 attagagtta tcgaaggact cgatacgtac tggggtcggg atttggagca aacgccctag
   102901 attttcaata gctccttgag tcttttcgac agatttttct agcaggttaa atttctgctc
   102961 cagactaaca cgtgcatttt ttatggctag attgaccagt tgttttttct ctccacgttg
   103021 aggcttaaga atcttggaat ccaccaaggc cttgacagcc tcttcgtcaa tatcctgcgg
   103081 aatcagtacc tcattgggaa ctagatgaga tttttcttga tagaattgtc ctacataggt
   103141 caaaaaatcc tcatctggat cattgaagta ggggaagaga ttgacatcgc gctcgataag
   103201 cttaccctga cggacaaaga aaacctgcac acacatccag cccttatcca catagtagcc
   103261 aaagacatcg cgattttgca aatctttcgc catgacccgt tgcttggttc gaagcgttcc
   103321 aatagcctga atcaggtcac ggtattccgc cgcacgttca aactccatac tttgtgctgc
   103381 tactgccatt ttactcttga gatcatcgat gattttgtta tcctgccctt tcagaaaatc
   103441 agaaacctcc tgggccatag acttgaaata agtctcatcc ttcttacaga tggtgtgggc
   103501 catgcattga ccgatatggt aataaaaaca gaccttagag ggcgggttgg tacacttacg
   103561 aaaagggaat atccgatcca gcaaccgctt gatttcattg gctgccccca catcgggata
   103621 gggtccaaaa taaagacctc cgtccttttt gacctgacga gtgataatca agcgtggata
   103681 gcgctcattg gtgattttga tgaaaggata ggacttgtca tccttgagca tgatattgta
   103741 cttgggcttg ttttccttga tcaggttgat ttctaggaga agtgcctcaa tattagactc
   103801 cgtaacaata aattcaaaat ccacaatttc agacaccaga gcctctgtct tggtatcatg
   103861 acttccacga aaataggacc gtactcgatt acgcagattt ttagcctttc ctacatagat
   103921 aatggtgcca tttttatcct tatgaatgta gcaaccaggg ctggtcggca agagctctag
   103981 ttttgattta atcaagttgt tcatagttcc attatagcaa aaaaagtagg gaaagatagt
   104041 accctactca ttagtctcat atatttttcg gaggtttgca acatcctctt cctggatacc
   104101 ataaaaggaa cctgctggtt gcatgacaga cttctcatct gtatggtcca agccaatcgc
   104161 atgacctaac tcatgttctg ccgtatggac aaggcgttca taggaatagc catagtatgg
   104221 attggacaaa taataatgat tcaaccgcac cgttacggac aagaattgcc ctgttaagag
   104281 attagtttga ctttccgcct ctcctgccac aggagtgcct ccgtcgttca tctccgtagc
   104341 cgtaatatcc gccttactag actcagtcac gagttcaaag ttaaaagcac cagtttgatt
   104401 ccagttctgg attgcttcta aataagcctc ttgaaagcgt gaatccatct gcggatccag
   104461 gtaaatacga gcagaggcct gtggccacct tccttcagaa tgctggtgac tatctgtctg
   104521 gcttaactta ggcagttgcc ctgttttctc ccattggtca atactttgtt gaccaatttt
   104581 tactgaccgt tctgcttgct ttagcgctcc ttgaaaatcc ccgttcaaat accagagaag
   104641 tccgaaagca agcacacata agagcacaac tatccaaacc agacgccaaa acaaacgcca
   104701 cacaaaaaaa aagaaagccc ctatcaaacg aaaaagccag cgcatgtctc tccacctttc
   104761 tagcaaataa aaattatttt actaaaagaa gctaaaagaa atctaaatac tgactttttc
   104821 atcttaacgt cctactattt ttttgagtaa ctggatagct ttgtatttta aaggcgatgg
   104881 atggtaacgg aaagtacccg ctttgcgtac aatatagcca ttaaaattct gtttaaaacg
   104941 caaaacacca tcacttccat caaaaatccc ttgaatgcct aggaaattgt atttaggtat
   105001 tccacgtttt atgctttcca acataacata tttttgaagc agtgcagggg catagaactt
   105061 attaaactca gtgtaggaac cactaaagag ataagtcgtt tcctgaggca tataaacaaa
   105121 taaactccca gctaaaacaa tatcttcttc tccatatttt tcaatcaagt ctcgcgcttc
   105181 tgcttttcga acttcaaacg tttcaaattg actagaatat tctctcagtt gattttgttt
   105241 tttctcagaa tgaggatttt tactcaaatc aagtcgcaac ttgtccaagt tttcttctag
   105301 tttactttgt tcaccttgca atttgctcat atactccgaa aaattcaagc ttgctatgag
   105361 aaactccgct tgttctccaa aagtatcata aaaatgctca taatattcta aacttttatc
   105421 actatattct ctacgttcag aggtttcttt tgttatattc ttaaaaatcg atagttcttc
   105481 acgttttaac tttttcaacc gaatgccaaa ggtttcagcc tttttcacca agggtttacc
   105541 ctttttgcta aaacttttaa gcaaactctt ttcagttaat tcagttaaat ctttatagta
   105601 taaccaatct ggttctccac ctgggtaacc tgttgttaag ccatcaaatt gataacctaa
   105661 atcagtcaaa ccttgaataa tacttttttt ctcagcatct attggattac cttggctatc
   105721 aaaagtttga taagtttcat aaggttttac aagcaactct aatacaccat tttgcttggc
   105781 atattctttt aactctgcat aaaaaactgg aagagcatct tgttgggtat aaatcggccc
   105841 cgaattgagt tccatatgca gaccacccag catgggcaag ctataaacca gagctgcaac
   105901 ttgaatttct ccttcttgtt tcaaagcaag ataaacaatt cgagcccctc ttttttctag
   105961 caaatccccc atctggacag attgcataaa ggaacgagaa gaaacctgat cagaataagt
   106021 ctgaaactct tctttcgtga gtgttgttag tgccatatac ttactttcta tgtttttttc
   106081 ttaatgtttt acggaaatca agagcaagtc ttaacagagg atagagagga tgagtgggca
   106141 ttgtaaattc acccaagtat tcttcaatcg ttggattaaa tttttcctta aaatgataaa
   106201 gtccaccatt gagagagttt tcaacaccac ctaaattttg ccagaccata cctcgctcaa
   106261 aggcatagcg agccgtttca taccatgtta aaattggtgc attgtaacgt ttaaaatcat
   106321 catccatacc agcatatata ttgacagagg tagtaccaaa ttccaaactc aaagtagccg
   106381 ctaaaggaac tctcgcttga cctacatcta tatattcctg caagaaggtc aattcctcta
   106441 acaaacgttc tttttccttc ttctgcgctt ctacttttga aattcgagtc gactcagtaa
   106501 acgtctcttc caaggctcta tttttcgcta actgttcttc taattcttgc gaacgtttag
   106561 aaacatccaa ggtggccaag gtgatatagg ccttgtcctt aaaattatct aacaattttt
   106621 tataataggc ttcattcctc aaatgaatct cttttcgctt ctcagttttt ttcatcaact
   106681 ccgaaaatga atctaatagt tccagtccac catattgaat ctcaagccct ttgtttcgtg
   106741 ctgttcgaat agcctgtttt gttgacttgg aaagtttatc ttcttcaaaa ttttccttgt
   106801 atattttcgc ctgaatacga ggttgaatgg tgtctcccat ttcctccgtt tttcctgacc
   106861 accttactcc catttgttgc aaactatcaa taatagccag attttcagga aattctgtct
   106921 tttcctgatt gattaaactt tgagataggc aaatacttgg gtcaaaagtc acaaaaaccg
   106981 ctctcttact gcgagcatag gacttaatag actgaatggc aaaattcaag agttctttat
   107041 ccccataatc caatataggt cctcttggga tgtaaaacat tttatagcct agcggaagag
   107101 ttctaatcaa aatactagct gtcgccagta atttttcttc cctgtaaaca ccaaacttct
   107161 catgttgcca attagactta acttcctccc aagcactact ttgtaataca ttggctaatt
   107221 catgttcttt gacaaactga tcatattcta atgtgggaat gccaatttga taacggtaca
   107281 tttcctactc tctttcctcc agtattttat tactattcta ctactttcgt ttgaaaagtc
   107341 tagtgaaaac atattttatt ttagttctac tccccctatg ctgaagttca aactaagtca
   107401 gtctctcttc taatttgaaa tcaattggta gggttgttaa aaaaacttcc aattgttttt
   107461 cccagtagta ccactcgtga gttccagcac tatggctata ggtcacatca aaacctagtt
   107521 ttttgagatt tttcactgcg agattattgg cttcgtacaa gaaatcctgt tcgccacacc
   107581 acgcccaaag tttggtcttt ttatccgatt ttttagccag actttcaaga gaatagggac
   107641 tagttgtcca gtctctaatc tctccaaaaa cacctctcca gtaggctgga cttcccagat
   107701 tttgactttc aggagaaaag ttttgaaagc tgagggcacc tgaaaaacta gctgcatgag
   107761 aaaaacgatt tgtcgtaaga gccagtttga agcagccgta gcctcccata gaaagaccag
   107821 cgataaaggt cttttcacgc ttgctagtca tattagggaa gaagcgtttc agaacctgtg
   107881 gcaattcctc tgctagagcc gtgtagtagt caaaaccata ctgggtgtcg gtgtaccaac
   107941 cattgctggt attgggcata acaacgatga gattagttcc tcgaagcaag cgttctacat
   108001 tggtccgctt aagccaacta ttatgatttc cagacatccc gtgcaaaagg tacaagacgg
   108061 gaatatcttc acactctggt tcttccactc gattggcatc agggtagagg acattcaccc
   108121 cccactccat atccaatact tgtgagtaat actcgatttt cattactgcc atgattttct
   108181 ccttctattt ttctataaga aaaagccgaa actcgacttt ctctctgttt atttcaacga
   108241 ttattttgct tccatgacta ctggtaaaat agctggacga cgcttggttt ggtcaaagag
   108301 atacttggtc aaattatctc gaaccttccc tttaagatct gcccagtcaa agtcatctcc
   108361 ttgaagataa tcttctaccg tttggttaat caattctgaa ctttcacgga gaatatcgcg
   108421 actcttcttg agataaacaa atccgcgcgt atgaacacga gccctagcca caattttctt
   108481 ctcacgacgg ttgactgtaa tagccacgat gaaaattcca tcctctgaca agaccttacg
   108541 gtcacgaaga acaacatttc caacatcacc aatggcattc ccatcaatta agatatctcc
   108601 tgctgaaacc gatccagctg gaacaaagtc tccattctcg taagccatgg tcgtcccctt
   108661 tttaggaatg aagatgcgtt ctggcaacat cccaactgcc atggcagcct tagcgtgagc
   108721 atccaactca cgatactccc cttggacagg gaagaggtac ttaggttgca aaagattgat
   108781 catcagctgc aaatcacgca catttccgtg ccctgataca tgtaaacttt gggtaatcaa
   108841 tttgacaacc ccacctgcct gataaatcat attttccaca cgcgcaacaa aggcttcttt
   108901 agcaatagac ggagccgtag caatatagac caggtcccca tccttgattt ctacataacg
   108961 atggcgacca atcgacatct tacgaagtcc attgataggt tcacccatac gacctgtctc
   109021 aagaataatc aactcatggt cttcaaagcg agacatatct ttaggcttaa tcaagagaat
   109081 ttcgttggct aaagacaact tcttaagacg aatcgctgtg cggacgatat tttcaatatc
   109141 aaatcctgtc aagacgatac gtcgacctgt tttatccgca gcgtcaaaaa tctgctgaat
   109201 acgagaaaga ttactggaaa cagctgcaac gatgatacga ccttcccagt cagcaatagt
   109261 ttgggtaatt tcatccctaa cttcactttc actagccacc tgaatattgc tgtctgcatt
   109321 ggccgaatca ctgaggagag ccagaacgcc gtcacgacca atctctgcca aacgagcaaa
   109381 atcagttgca taagattcac tagccgtttg gtcaaatttg aagtcacctg tataaacgat
   109441 gcttccttcc gatgtcttca agacaattcc cagactctct ggaacggagt aagtcgtagg
   109501 gaagaaggaa accactgtcc caccaaaatc aatctccgta ttctcatcaa tgacatggaa
   109561 atcattaaat ttcttaacgg catcatttcc tttgacaaag agctttgcca actcaatggt
   109621 caactcagac ccaaatacag gaactttagc ctctgccaag agataaggta gagcaccaat
   109681 ggcatccgca tgcccgtggg tcaagaaaac cccagcaata cggtcgctat tttcaaaaag
   109741 gtaatccatg tttggaatca ccacatcgac ccctaattgt tcattttcag gatattttaa
   109801 ccctacattc aaaacaaaaa tggactctcc aatttcagca atgtacatat tttttccatt
   109861 ctcacgcaca ccaccaagtg ttgttaaact gatattactc atttttcctc caaaatctta
   109921 gtttatcttg attatagggc aactctaccc tcttattcta aaagttctaa tactttcagc
   109981 cgaatctttt cctaccatta taccattttt ttgatgattt tcaaaatgaa ggtctgtttt
   110041 caaaaaagag ttgatttccc aactctttcc taacttctac tctttttcca tcaaaaaatc
   110101 ataaatttct tgcaccgtac ccagcgccat catttcttgg tctttaacgg tttgtttgag
   110161 attttggtaa atttgacttt ctcctatctc ccgctttggc gcctctttat tgactgtcat
   110221 cacaccatct tttatcgtca caaagcctag ttcttcaaat acttgaatca tcttgaccag
   110281 caagatttgt tgaatattaa gatatgcagc caaatctttc agcttgtagc gaatatcaaa
   110341 ctctgggaac tggtaaatag tcttgtacaa tttggcaaac tgatctctag tcccataacc
   110401 tgtcagataa taggccttgt caatatcatt tttgaaatag acagcagaga aatgctgttc
   110461 ctgaaaaatg gtcttcagct gagtaatact ctctggaatg ttttttacga caacagcttc
   110521 actagccgca agatttggca gttctccagg aaaatccaag actggaacac cttctggcaa
   110581 gactgtattt tttccacgaa tgttaaaaag ttgaacacct tccactcgcg catccaccat
   110641 catcaactgg agggcagttt ggccattcca ttggttgaca gacaatttaa ccgctaactc
   110701 tagattcttg gtttgagaaa actctgtcgc ccatctgcct tgaccaaagg ctaccacttc
   110761 aaaactcgcc tcacccttgg aaattttcag ctttagatgg gcattacctg cccccatagt
   110821 acgagcactt tcgacctgaa aattcttgat ataaaaaata ggtttctgat tatccattcc
   110881 aaaaggagct aaacgttcaa aacttttgac cgtttccaag ctaagtgcct ccaaatccaa
   110941 ctcttcatct aggtttaact tattctttcc accagcatct gcaccttttt cacgaacata
   111001 atcttccaaa acctgagata aatctgagag ttgctcaact tccagcgtca tacccgctgc
   111061 acctgcatga cctccaaagg cgatgaagag gtctcgatgg ggatccagag cttcaaaaat
   111121 atcgaccgct tccacactac gagcactgcc cttggcacga ccgtcttcta tattaagaac
   111181 aatgactgtc tgtcccaatt cttccaataa acgaccagcc acgattccta gaaccccagg
   111241 attccagcct tccttggcca agacctgaac cttcttctca ggatccacca tggtcttggc
   111301 ttcttcatag atagactgaa cgatttcctt gcgctcttcg tttttctggt gaatcataag
   111361 ggcaatctca tgcgcttcct catcatcaaa tccagtcaac aaatcaatgg caggattggg
   111421 atcatccaag cggcccaagg cattcaaacg aggagcaatc tggaaaccaa ccgtttcttc
   111481 tgttacttcg ttggcagcaa tcccagccat gtccagcatt tcttgcagac caatgcgctg
   111541 ggtatgaccc aacatttcca gaccatattg aactaagata cgattttcat ccgtcagact
   111601 caccatatct gcaatagttc caatagcgac caaatcaagc aattccactt gcacttcttc
   111661 taacagggca caagccaact tgaaagcaac tccacaacca gccaaatatt taaaaggata
   111721 atccgcatct ggatgttcag gatggacaat agcataagca tctggcaggg tttcaggcat
   111781 ggaatgatgg tctgtcacaa tgacatctac tcccatagac tgagccaatg caatagcctc
   111841 atgaccagca accccattgt ccaccgtcac aatcaaggaa atcccttctt gctcgataaa
   111901 gtatttataa acactagcat tagggccata gccatcggta aaacgatttg gcaggtaaac
   111961 tcggcactca gcaccaagtt gttccaaact ttccttcaca atagaagccg aagtcatgcc
   112021 atccgcatcg tagtctccat aaacgagaat attttccctt tcttcaatag cctgacgaat
   112081 ccgctccact gccttgtcca tatcatggag cagataagca tcatgtaagt cctccaagga
   112141 aggttctaaa aacttcttca gactttcttg gtcctgaatc cctctctcaa acaataaccg
   112201 agccacctca ggacccagtc cagccttctt ggctatcttt gtaaaatccg catcttctac
   112261 ctgcagggca aactgccatt cataagtagg tgttatcaaa aagacatcca ctctttctaa
   112321 gaattctatt gcttcattat aacatgattt agacgttttc tctatccaga ttgctttttt
   112381 ataacatttt atagtatatt gaaactagaa tagtacacct ctacttctaa aatattgtta
   112441 gaaatcgatt tgactgtccc gatcgatttg tcctgttctt atttcactat agtgaatttt
   112501 ttcagatatg gtttgacaag aacattcttt tattgtagaa tcgtgttata aaatctgaca
   112561 taaatgagtt ctctcatggc tttagtagaa tttaaaaacg tcgaaaaata ttacggagac
   112621 taccacgcac tccgcaacat caatctccgt tttgaaaaag gacaagttgt tgtcctgctt
   112681 ggaccttctg gctctgggaa gtccactctt atccgtacga tcaatggttt agaggctgtt
   112741 gacaaaggaa gtctcctagt caatgggcac caagttgctg gtgccagcca gaaagatttg
   112801 gtacctcttc gcaaggaagt cggcatggtt tttcaacatt ttaaccttta tccacacaaa
   112861 acagtgttag aaaacgtgac acttgcaccc attaaagttc taggaattga taaaaaagaa
   112921 gctgaaaaaa ccgcccaaaa atatctggaa tttgtaaata tgtgggacaa gaaagattcc
   112981 tatcccgcca tgctatctgg tggacaaaaa cagcggatcg ccatcgctcg tggtcttgct
   113041 atgcatccgg aactcctcct ctttgatgaa ccaacatctg ctcttgatcc tgagactatc
   113101 ggagatgttc tagcagttat gcagaaactg gcgcgtgatg ggatgaacat gatcatcgtt
   113161 acccacgaaa tgggctttgc tcgagaggtt gcggaccgca ttatctttat ggccgacgga
   113221 gaagttttag tagatacgac agatgtcgat aacttttttg acaatccaag cgaacctcgt
   113281 gcccaacaat tcctcagcaa aattatcaac cacgaaagtg acaaagtcaa ataaggaggc
   113341 gcctatgaaa aaaaaattct ttttatcagc attattgatt agccttttcg gccttgttgc
   113401 tgccaaacca gtccaggcta atactagtat cgcagacatt caaaaaagag gcgaactggt
   113461 tgtcggtgtc aaacaagacg ttcccaattt tggttacaaa gatcccaaga ccggtactta
   113521 ttctggtatc gaaaccgact tggccaaaat ggtagctgat gaactcaagg tcaagattca
   113581 ctatgtgccg gttacagcac aaacccgcgg cccccttcta gacaatgaac aggtcgatat
   113641 ggatatcgcg acctttacca tcacggacga acgcaaaaaa ctctacaact ttaccagtcc
   113701 ctactacaca gacgcttctg gatttttggt caataaatct gccaaaatca aaaagattga
   113761 ggacctaaac ggcaaaacca tcggagtcgc ccaaggttct atcacccaac gcctgattac
   113821 tgaactgggt aaaaagaaag gtctgaagtt taaattcgtc gaacttggtt cctacccaga
   113881 attgattact tcccttcacg ctcatcgtat cgatgccttt tccgttgacc gctctattct
   113941 atctggctac actagtaaac gcacagaact actagatgat agtttcaagc catctgacta
   114001 cggtattgtt accaagaaat caaatacaga gctcaacgac tatcttgata acttggttac
   114061 taaatggagc aaggatggta gtttgcagaa actttatgac cgttacaagc tcaaaccatc
   114121 tagtcatacc gcagattaag gaggataccc tatgacagat ttatcatctt ggacagccta
   114181 ttttcaggat tttggacaat ttttcaatgg tttcctcttt actcttgccc tagcgattgg
   114241 atcctttatc ctcgccatgg tcttaggaat cttctttggt gccatgtcaa ccagtaaacg
   114301 tccaatttta cgcattttag ctcgcatctt cgtggaattt taccaaaaca ctcccctctt
   114361 ggtgcagttt gttattgttt tttatggcct acctcttatc agtgaccaca tcatcatgat
   114421 tccaatttat tggacagccg ttctctgcgt gggactctat cacggcgctt atatcgctga
   114481 ggttattcgt tcagggattc agtctattcc tagtggtcag atggaggccg ccttgtcgca
   114541 aggttttacc tatatcagtg ccatgcgctt gattatcttg cctcaggcct tccgcatcat
   114601 tctccctcca ttgaccaacc aaattgttaa cctcatcaag aacacatcta ctgtagctat
   114661 catctctgga gtagacttga tgtttgtgac taagtcttgg tcggctctca acggaaacta
   114721 tatcccagcc tttttaggtg ctgctcttct ctactttgcc ctatgcttcc ctgttgccca
   114781 gtttggtcgc aagatggagc aagccaataa aaaagcctat tcactttagg aggttactat
   114841 ggaatctatt ttagaaattt taaccccaga taacctagtc tttatcttta aaggatttgg
   114901 cttgaccctc tatatttctc tgattgccat catcctctct actatcatcg gtaccgtgct
   114961 tgccgtcatg cgaaatggaa aaaatcctat cttacgcatt atttccagta tttatatcga
   115021 gtttgtgcgc aacgttccca accttctctg gatttttact atctttttgg tgttcaaaat
   115081 gaaatccaca ccagcaggta ttacagcctt tactctcttt acatcagcag ccttggctga
   115141 gattattcga ggcggtctca atgccgtaga caagggacaa tacgaagcag gaatgtcaca
   115201 aggcttcacc tcagcccaaa tcctctacta catcattctc ccacaagcca tccgcaaaat
   115261 gctaccagcc atcatttctc agtttgttac cgtgattaag gataccagtc tcctctactc
   115321 tgttatcgcc ctacaagaac tctttggagc cagccaaatt ctcatgggcc gttatttcga
   115381 accagagcag gtcttcagtc tttacatcct gattgccctc atctacttca gctttaacct
   115441 agcgatttct agcctgtctc atatgctagc caaacgttgg caacaagctg cagaataata
   115501 ctcttcgaaa atctcttcaa accacgtcag cttcaccttg ccgtactcaa gtacagcctg
   115561 cggctagctt cctagtttgc tctttgattt tcattgagta taaacagcca ctctccagtt
   115621 caattggaga gttttttgat gagagtagat atttatagac ctcaatttga caccatacat
   115681 tttctatgat aaaatgtaac aaattcattt acaacaaatc gaaatctaaa tgaaatggaa
   115741 ttttctatga aatcagtcaa aggactactc tttatcatag ctagttttat cttgactctt
   115801 ttgacttgga tgaacacttc tccccaattc atgattccag gactagcttt aacaagccta
   115861 tctctgactt ttatcctagc cactcgtctc ccactactag aaagctggtt tcacggtttg
   115921 gagaaggtct acaccgtcca caaattcaca gcctttctct caatcatcct actaatcttt
   115981 cataacttta gtatgggcgg tttgtggggc tctcgcttag ctgctcagtt tggcaatctt
   116041 gccatctata tctttgccag catcatcctt gtcgcctatt taggcaaata catccaatac
   116101 gaagcttggc gatggattca ccgcctggtt tacctagcct atattttagg actctttcac
   116161 atctacatga taatgggcaa tcgtctcctt acatttaatc ttctaagttt tcttgttggt
   116221 agctatgccc ttttaggctt actagctggt ttttatatca tttttctata tcaaaagatt
   116281 tccttcccct atctagggaa aattacccat ctcaaacgct taaatcacga tactagagaa
   116341 attcaaatcc atcttagcag acctttcaac tatcaatcag gacaatttgc ctttctaaag
   116401 attttccaag aaggctttga aagtgctccg catccctttt ctatctcagg aggtcatggt
   116461 caaactcttt actttactgt taaaaattca ggcgaccata ccaagaatat ctatgataat
   116521 cttcaagccg gcagcaaagt aaccctagac agagcttacg gacacatgat catagaagaa
   116581 ggacgagaaa atcaggtttg gattgctgga ggtattggga tcaccccctt catctcttac
   116641 atccgtgaac atcctatttt agataaacag gttcacttct actatagctt ccgtggagat
   116701 gaaaatgcag tctacctaga tttactccgt aactatgctc agaaaaatcc taattttgaa
   116761 ctccatctaa tcgacagtac gaaagacggc tatcttaatt ttgaacaaaa aaagtgcccg
   116821 aacatgcaac cgtctatatg tgtggtccta tttctatgat gaaggcactt gccaaacaga
   116881 ttaagaaaca aaatccaaaa acagagctta tttacgaagg attcaagttc aaataagtaa
   116941 tcatactctc ctgggatttc ccaggagagt tttttatagc caaatgaaat aagacctgaa
   117001 cgatggaatt ttggcattca aatcaattga taagaatatt ttatagtgga gtgaaatagg
   117061 atacgaacaa attgattagg aaaatcaaat gaatttatag aaatctttta gcagttatgt
   117121 tgtcctattc tagtttcgaa acgctataga agcagcattg tgctagtcta gattcagttt
   117181 actatactaa aacgagtagc ttgaaatcaa aaaacccacc ctcacaggca ggttttatct
   117241 gtattattca gctagattat gctttacctt ctgaaccgaa tacgtcgata cgttcttcaa
   117301 ccgatgcttg gatagctttt acaccgtcag ccaagaattt acgtgggtcg aagagttttt
   117361 tcttgtcgta ttctgcttcg tttgcttcgt agtcacgagc aaatttacga gttgcgttag
   117421 cgaatgcgat ttggcattct gtgttaacgt taactttggc aacaccaagt ttgatagctg
   117481 cttggatttg ctcatcagga atacctgatc caccgtgcaa tacgattggg aatcctggaa
   117541 gagcttctgt caatttttgc aagtggtcaa ggtcaagacc ttcccagttt actgggtaag
   117601 ggccgtggat gttaccgata ccagctgcca agaagtcgat accagtttca accattgctt
   117661 tagcgtcttc gattggagcc aattcacctt taccgatgat tccgtcttct tcaccaccga
   117721 tagtaccaac ttcagcttct actgagatac ctttagcgtg tgctttttca acaacttctt
   117781 tagccaattt aaggttttct tcaactggaa ggtgtgaacc gtcaaacatg attgaagtat
   117841 aaccaacttc gatacactca agtgcatctt cgtagtgacc gtggtcaagg tggatagcta
   117901 ctggtacagt gatacccatt gattcaacaa ggttagcgat caagttgcga gcaactttgt
   117961 aaccacccat gtatttagca gcacccattg aagtttggat caaaactgga gcttttttag
   118021 cttctgctgc gcgcaagata gcttgagtcc actcaaggtt gtttgtgtta aatccaccaa
   118081 ctgcataacc gttgtcacgg gctgcttgga caaatttttc tgctgaaacg attgccattt
   118141 tatcaggcct cctgtatatt tttatgggtc atcccattta cattgttcat tttatcactt
   118201 tttgccaaaa aaatctagtt tttcccgcag tttcgattga ttttcttcta actccatcta
   118261 tgtaaaccct ttctctccct agtcttggac gacttttgga aaatctataa agaaggttaa
   118321 acgattctcc tccatctcga aacgataagc taatttttca tgttctaata gactcttaac
   118381 cacaaagagc cccataccag accccttgac cttgcgactg gcattgtcag aaaaagactg
   118441 ggctagtttt tcttgttcct ctgagctaca gctattttcg ataaaaagtt ctccttctct
   118501 ttctccaatt cgaactaagc cacctggaac agagtgctta atggcattgc tgatgagatt
   118561 agaaagaatc aacttcataa ctgatgggtt tagataagcc tgctgatggg tcaaactatt
   118621 gtctatctgg agctctcttt ccttggctag caaggcataa tctttgacca gattttgcgt
   118681 catctggagg aggtcaattg tttccctatc atctcgcaat tcctgcacag aagagaggga
   118741 aagtatctgc agaacatggt gattgagttc atccacaatc cccaaggcaa ctcccagata
   118801 ctggtctcta ttcttataac gaccgatatt ctctctcata ttttcgatta ggattttcaa
   118861 actagccagc ggtgttttca attcatgaga agctcctcgt aggaattcga ccttcatctt
   118921 ctccagctgg agaatggctt cattcttttc atgcaagtcc gcaataacag tcaagagatg
   118981 ctggtagagg ctattgattt gttccttgag attgcctatc tcatccttag aatccacgcg
   119041 caatcgcact tgggaatcca ggtccatcat ccgacgggtc acccgcttga tttccaaaat
   119101 cggtgcaaca atagtccgag cgtagatgta ggccaccaag agggaaatca gaaaggaggc
   119161 cagcaaggta tagggaagaa attggagact gatttgctcc gcttcctttt gtaaatccat
   119221 ggaagctaga aactggagaa tcatagtacc accgtcttgc gttttcacct cgcgctcctc
   119281 aataaagaga gaggttgtat ggcggtctgt gtccagagga agactgtcct tgacttctaa
   119341 cttgtcctcg gtcatctcac ctttgacggt ccccttgata tcactagtct gggaatacaa
   119401 gtctaacact tgctcgatac tctgcctatc tttcccttct agggactggg caatggctgt
   119461 tgccttttga ccaatggttt cctgacgatg actcagataa gtcgaaggaa aaagaaaata
   119521 aatagctaaa tgaaggcaga taaccagaac actaaatatc gagaaggtat agataaatat
   119581 ctttgtaaat aaacctgttc gtttcatttt cgctccaatt tataaccaac attgcgcaca
   119641 gtgaggatac aatccaagtc tagctttttc cgcaattcct tgatataaac atcaataaca
   119701 cggtcaaagg gaacctcatc tgtcgctttc cagacggcat cgataatctg agaccgagtc
   119761 aaggcccggc cttcattttt cactagatag tccagaattt ccaactcttt ggcattgata
   119821 ggcacttctt gacctgcgag gcttgcactg tagctttcaa agtccacctt ggtatccttg
   119881 taagaaaaga ttcgtcctgt atcgtagtag cgcttgaaaa tcgcgtccac cctcactttt
   119941 aagagggaga gggagaaagg tttttccaga tagccatctg ccaaagaggc aaaggcactc
   120001 atcttgtatt cctcatcctg aaaagctgtc aacatcaaga caggaacctg actggtttta
   120061 cgaatctcag ctaggacttc taagccgtta agcttgggca tctggatatc cagtaaaacc
   120121 agggccacct catagctaga aaattgctcc agagcttcct gaccgtccgc tgcctcaata
   120181 gtttcatagc cacaatccgt caaataatca ctgaccccct cacggatcat ctcttcatct
   120241 tctacaatta aaattttcat actttaactg ctctctattt tttatttttc ttagaataaa
   120301 tacctactct attttctatt atagtctctt gctggccttt tgtatgtaag caactgacca
   120361 ctagataaaa cgttgtgaaa ttcctttctc ataaattcca taactttagt atattatatt
   120421 taagcactaa agtacaaaga aagcaactga aagcaatgat tttcaccact gctttcagat
   120481 ttattttgaa ttgttaaata gctattccta tccactattc ttgaatagaa acacaagatg
   120541 caatctttat tccagactca tttttttcaa atttattcac catccagcaa gagctctttt
   120601 ggttgttttc taaggagatt gcttgaagca agcgccataa cgagaaccac tagaaccaag
   120661 gcaaggacaa aaatgatgat aaagtctgat gtctgaatgg aaatgtctag gctcgacaag
   120721 gtcttgctaa agccatctac ttctgcaccg ccaccaaggt tagaggcttg agccgcctta
   120781 ctagcctgtt tggcaacacc tgaagtcaca ttggcaagga cagtgtttcc aattgcacgg
   120841 gcagtgtaat tagctaggaa gtaagcagaa actagagcag ggatagcaat caagatagat
   120901 tcggtgatga attgacccaa gatacttgcc tgcttgagac caatagagag gaggattccc
   120961 acttccttgc gacgggcatt gatccaaaga ctgagcaaga gggcaaggag aaggactgag
   121021 aagctcaagc taccccagaa gaggaggttg gccatcttgt acataccaga gatagattgc
   121081 tcaagagctg ggtagttaga ggagctcttg acgagtgtgt agctcttcca gttgatacca
   121141 ctgatgccat tcaactcttt cataacatca tccaagttct tgtctgctgt tacaaagaag
   121201 gttgcgtccc cataaatggc tgtgtcttct gtgtatccat aaagttttgc agcagtgtga
   121261 atgtctgtaa tagctgtgtt ttcgtaaagt tcttgtgagt aggttactgc tgacttatta
   121321 tgaccatcaa agagtccctt gattgtcact tcaactgttt ccttggctcc tttttcatta
   121381 tctgcatcgt agatattaga gtccagttta accttgtccc ctactttcca gccgtgtttg
   121441 gctgccaagt ccttgtgcaa gaggatttta tccttgtcgt cgttggttaa gtgctctcct
   121501 tcgactagtt tataagaacc agagacaaac ttgtcttctt tagaggagtc attgacacct
   121561 gtaatcatca agctacttcc aaaacgtttg gcacgatcag cagtgagatt cttcttggtt
   121621 tctggcgttt caatcaggtc atatccagtc aaatctccga tagcgttgat acgtttgaca
   121681 taagactcaa tggccttgtt ttcggtgatt tttttgatgt cttcaccctt gatattccca
   121741 gcaccacgag gcgttccttg gttgacgcga cgattgattt gcatggagaa gctattggtg
   121801 atatttttaa aggtctcctg agaagccttg gcagtagctc ccttgattga caagccgacc
   121861 aaactcaagc tcgccataag gagaataatc aggaagatga caatcgattt gaaaaacttc
   121921 cttgtaacat aggcaaatgc gttgtgtaac atagattccc tttctagatt ttgttttaat
   121981 cattctatca aaataagctc aaattattta ctagtattgc gcgtttcagt cagtttctta
   122041 tcctttaatt caagtgtaat atctgacgct tgtgccactt ctttactgtg agttacgaca
   122101 atcacacatt tacctgtttt ctgggcaagt gatttgagta gttcgacaat atctccagca
   122161 gttttaggat ccagatttcc tgttggctca tcagctagaa taactggagc ttctgagacc
   122221 aaactgcgag caatggcaac acgttgctgt tgaccacctg ataactggag aacattccgc
   122281 ttaatctggc tttcatccaa accaagctca agaagtgtat tcttgcttgc ctttttgttg
   122341 accaattgga tattttccag cggagaaaga taatctatca agttataatt ttgaaagacc
   122401 agggaaatat ggtgcatgcg atggtaagaa tagcccttct tacgaatatc ctctccttga
   122461 aaaaggatag aaccttcaac aggactatct agaccagcaa gtagggacaa gagtgtggat
   122521 tttcctgctc ctgactcccc aataatactg taaaattttc cgggttcaaa attataattg
   122581 atctgatata ggactgcttc agcagtattc ttataacggt aggtaacatc ttgtaattgt
   122641 aataaagtca tgatttctcc ttcttaacta atagatgata aaatttcttt cggtgatttt
   122701 ctaaataaga ataggaaaca aagggctaca gataagcaac taagcagaac tagaaaaaca
   122761 taggattctg caaaagataa gatgctagtt gataaactgc ttgctttggc tagtgtatct
   122821 tgtaagctta cctgatctcc acttgctagt agagtttgga gtaggtaagt tgtgattccg
   122881 tttcctgcaa caaatgctgg aagcaaagct ccaagagata ccaaaactac ctctaaacag
   122941 aattgtagga agatcgagct cttgcctttt ccaagtgcaa gtaaaatccc cacttcatag
   123001 acccgttctc tcaaccagag agacaaaacc agaattaagg ctccagctcc tgctatcaac
   123061 atcccataaa ggaagatggt caggaaggtt tggaaagttg caactgagtc tttgatttgt
   123121 tcaaaagcct tgttttcctt ttcgacttgg tagccttgat tttccaaggc caagttttct
   123181 acctgcttca tgagtccgtc catttcctta ggattttcta catagaagcg tgctgcactg
   123241 acttgagctt cactattgcc caaaagggtt tggctacttt cataatctgt aaagacttga
   123301 ttttcactga agtcagaaga caagcctgtg aatttctctt gttttttacc agaaaagatg
   123361 ccgataatct caaactctac tgtttgtcct tttccagatt cagactgacc agcatccaag
   123421 ccaatcttgt catgaagtga aagaccgttc ttcttagcca attcttcgtg gataaggatt
   123481 ttcttggaat cccctttttg aaggtgtcgc ccttctttta gattgaaagc cgaactggta
   123541 aaggttacat ccttggatga atcctcaaga gccgttaagc taaccaagtt attgtctgca
   123601 gctgataaat catcacgctc cacgctctgc tcgccagtca ctgcttcctt gtcttttagt
   123661 tttgcgaccg tctcaagttc aggagagaca ttttccagcc ccttaatctt gcttacagat
   123721 gctaggtctg acaacttgaa tgtctgacca ttctctatct tcttaataga aaaagatgta
   123781 ttgagtgatt tataaagatt gctttctact gttttgttgg acttcatcag agtcaaacag
   123841 gctgaaattc cggccaataa gaccaataaa atcagaaata aaataaaact tctcagtcgc
   123901 tttctgctga cataagccca agatctttgg attggattca tttgtcacct ccatatttgt
   123961 aagactatta taaaacccaa atatgaaatg tttatgaaat acgaaaaaaa aaa
//
LOCUS       DAVKAU010000002        90126 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVKAU010000002 DAVKAU010000000
VERSION     DAVKAU010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 90126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.002"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(552..2279)
                     /gene="ezrA"
                     /locus_tag="VWX48_000118"
     CDS             complement(552..2279)
                     /gene="ezrA"
                     /locus_tag="VWX48_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU9170844.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHASDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2361..4307)
                     /gene="gyrB"
                     /locus_tag="VWX48_000119"
     CDS             complement(2361..4307)
                     /gene="gyrB"
                     /locus_tag="VWX48_000119"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU9170845.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAE
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLAAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4322..4885)
                     /locus_tag="VWX48_000120"
     CDS             complement(4322..4885)
                     /locus_tag="VWX48_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9170846.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNQGGRHFLVS
                     HRNDQVLEILEKPSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4970..5524)
                     /locus_tag="VWX48_000121"
     CDS             complement(4970..5524)
                     /locus_tag="VWX48_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU9170847.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5535..6758)
                     /locus_tag="VWX48_000122"
     CDS             complement(5535..6758)
                     /locus_tag="VWX48_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9170848.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6795..9245)
                     /locus_tag="VWX48_000123"
     CDS             complement(6795..9245)
                     /locus_tag="VWX48_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU9170849.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SHSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9445..10374)
                     /locus_tag="VWX48_000124"
     CDS             complement(9445..10374)
                     /locus_tag="VWX48_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9170850.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10514..10801
                     /locus_tag="VWX48_000125"
     CDS             10514..10801
                     /locus_tag="VWX48_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU9170851.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10835..12169)
                     /gene="ciaH"
                     /locus_tag="VWX48_000126"
     CDS             complement(10835..12169)
                     /gene="ciaH"
                     /locus_tag="VWX48_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU9170852.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12159..12833)
                     /gene="ciaR"
                     /locus_tag="VWX48_000127"
     CDS             complement(12159..12833)
                     /gene="ciaR"
                     /locus_tag="VWX48_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU9170853.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12942..15488)
                     /locus_tag="VWX48_000128"
     CDS             complement(12942..15488)
                     /locus_tag="VWX48_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU9170854.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15611..16051)
                     /locus_tag="VWX48_000129"
     CDS             complement(15611..16051)
                     /locus_tag="VWX48_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU9170855.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(16026..16895)
                     /locus_tag="VWX48_000130"
     CDS             complement(16026..16895)
                     /locus_tag="VWX48_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU9170856.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16937..17665)
                     /locus_tag="VWX48_000131"
     CDS             complement(16937..17665)
                     /locus_tag="VWX48_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9170857.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17673..18152)
                     /locus_tag="VWX48_000132"
     CDS             complement(17673..18152)
                     /locus_tag="VWX48_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9170858.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(18163..18861)
                     /locus_tag="VWX48_000133"
     CDS             complement(18163..18861)
                     /locus_tag="VWX48_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU9170859.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18854..19120)
                     /locus_tag="VWX48_000134"
     CDS             complement(18854..19120)
                     /locus_tag="VWX48_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU9170860.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19186..20112)
                     /locus_tag="VWX48_000135"
     CDS             complement(19186..20112)
                     /locus_tag="VWX48_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU9170861.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20187..21002)
                     /locus_tag="VWX48_000136"
     CDS             complement(20187..21002)
                     /locus_tag="VWX48_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170862.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21006..21326)
                     /locus_tag="VWX48_000137"
     CDS             complement(21006..21326)
                     /locus_tag="VWX48_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9170863.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21702..23699)
                     /gene="metG"
                     /locus_tag="VWX48_000138"
     CDS             complement(21702..23699)
                     /gene="metG"
                     /locus_tag="VWX48_000138"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU9170864.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEKSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23823..25082)
                     /locus_tag="VWX48_000139"
     CDS             complement(23823..25082)
                     /locus_tag="VWX48_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9170865.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENTNLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVCMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25084..25785)
                     /locus_tag="VWX48_000140"
     CDS             complement(25084..25785)
                     /locus_tag="VWX48_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170866.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELIERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25769..26968)
                     /locus_tag="VWX48_000141"
     CDS             complement(25769..26968)
                     /locus_tag="VWX48_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU9170867.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27254..28600
                     /gene="gor"
                     /locus_tag="VWX48_000142"
     CDS             27254..28600
                     /gene="gor"
                     /locus_tag="VWX48_000142"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU9170868.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28797..29333
                     /locus_tag="VWX48_000143"
     CDS             28797..29333
                     /locus_tag="VWX48_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU9170869.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAILSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGIAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            29384..29470
                     /locus_tag="VWX48_000144"
                     /pseudo
     CDS             29384..29470
                     /locus_tag="VWX48_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29539..29754)
                     /locus_tag="VWX48_000145"
     CDS             complement(29539..29754)
                     /locus_tag="VWX48_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU9170870.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29852..30172
                     /locus_tag="VWX48_000146"
     CDS             29852..30172
                     /locus_tag="VWX48_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170871.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(30202..30540)
                     /locus_tag="VWX48_000147"
     CDS             complement(30202..30540)
                     /locus_tag="VWX48_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170872.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(30552..31271)
                     /gene="trmD"
                     /locus_tag="VWX48_000148"
     CDS             complement(30552..31271)
                     /gene="trmD"
                     /locus_tag="VWX48_000148"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU9170873.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFNSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(31261..31779)
                     /gene="rimM"
                     /locus_tag="VWX48_000149"
     CDS             complement(31261..31779)
                     /gene="rimM"
                     /locus_tag="VWX48_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU9170874.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(31810..32598)
                     /locus_tag="VWX48_000150"
     CDS             complement(31810..32598)
                     /locus_tag="VWX48_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9170875.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(32702..32945)
                     /locus_tag="VWX48_000151"
                     /pseudo
     CDS             complement(32702..32945)
                     /locus_tag="VWX48_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(33175..33414)
                     /locus_tag="VWX48_000152"
     CDS             complement(33175..33414)
                     /locus_tag="VWX48_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU9170876.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(33434..33706)
                     /gene="rpsP"
                     /locus_tag="VWX48_000153"
     CDS             complement(33434..33706)
                     /gene="rpsP"
                     /locus_tag="VWX48_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU9170877.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33885..34085
                     /locus_tag="VWX48_000154"
     CDS             33885..34085
                     /locus_tag="VWX48_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170878.1"
                     /translation="MNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMNLLAD
                     DSLAGDIILLWRIQFGTFTTET"
     gene            34564..34785
                     /locus_tag="VWX48_000155"
     CDS             34564..34785
                     /locus_tag="VWX48_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170879.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            34868..35671
                     /locus_tag="VWX48_000156"
     CDS             34868..35671
                     /locus_tag="VWX48_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU9170880.1"
                     /translation="MKKLATLLLLSTVALAGCSNVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILNTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(35727..37268)
                     /locus_tag="VWX48_000157"
     CDS             complement(35727..37268)
                     /locus_tag="VWX48_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9170881.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHDPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(37270..37752)
                     /locus_tag="VWX48_000158"
     CDS             complement(37270..37752)
                     /locus_tag="VWX48_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9170882.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLSWLLYKRLHKNKIRN
                     "
     gene            complement(37752..38837)
                     /gene="rlmN"
                     /locus_tag="VWX48_000159"
     CDS             complement(37752..38837)
                     /gene="rlmN"
                     /locus_tag="VWX48_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU9170883.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIEIVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVNHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLRFNTMKRDRQKVVAAVNP"
     gene            complement(38858..39388)
                     /locus_tag="VWX48_000160"
     CDS             complement(38858..39388)
                     /locus_tag="VWX48_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU9170884.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(39545..40150)
                     /locus_tag="VWX48_000161"
     CDS             complement(39545..40150)
                     /locus_tag="VWX48_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU9170885.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(40323..41360)
                     /locus_tag="VWX48_000162"
     CDS             complement(40323..41360)
                     /locus_tag="VWX48_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU9170886.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(41394..42329)
                     /locus_tag="VWX48_000163"
     CDS             complement(41394..42329)
                     /locus_tag="VWX48_000163"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU9170887.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(42882..44072)
                     /locus_tag="VWX48_000164"
     CDS             complement(42882..44072)
                     /locus_tag="VWX48_000164"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU9170888.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLIRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(44287..45630)
                     /locus_tag="VWX48_000165"
     CDS             complement(44287..45630)
                     /locus_tag="VWX48_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9170889.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATVPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45770..46585)
                     /locus_tag="VWX48_000166"
     CDS             complement(45770..46585)
                     /locus_tag="VWX48_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9170890.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(46637..48817)
                     /locus_tag="VWX48_000167"
     CDS             complement(46637..48817)
                     /locus_tag="VWX48_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9170891.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVAAYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            complement(49103..50029)
                     /locus_tag="VWX48_000168"
     CDS             complement(49103..50029)
                     /locus_tag="VWX48_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9170892.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            complement(50022..50714)
                     /gene="ftsE"
                     /locus_tag="VWX48_000169"
     CDS             complement(50022..50714)
                     /gene="ftsE"
                     /locus_tag="VWX48_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU9170893.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(50732..51827)
                     /gene="prfB"
                     /locus_tag="VWX48_000170"
     CDS             complement(join(50732..51754,51756..51827))
                     /gene="prfB"
                     /locus_tag="VWX48_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU9170894.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(51935..52591)
                     /locus_tag="VWX48_000171"
     CDS             complement(51935..52591)
                     /locus_tag="VWX48_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9170895.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(52899..53609)
                     /locus_tag="VWX48_000172"
     CDS             complement(52899..53609)
                     /locus_tag="VWX48_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170896.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(53609..54373)
                     /locus_tag="VWX48_000173"
     CDS             complement(53609..54373)
                     /locus_tag="VWX48_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170897.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(54373..55329)
                     /locus_tag="VWX48_000174"
     CDS             complement(54373..55329)
                     /locus_tag="VWX48_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9170898.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(55333..56202)
                     /locus_tag="VWX48_000175"
     CDS             complement(55333..56202)
                     /locus_tag="VWX48_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9170899.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(56470..57630)
                     /locus_tag="VWX48_000176"
     CDS             complement(56470..57630)
                     /locus_tag="VWX48_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9170900.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(57732..57980)
                     /locus_tag="VWX48_000177"
     CDS             complement(57732..57980)
                     /locus_tag="VWX48_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU9170901.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(58059..58649)
                     /gene="clpP"
                     /locus_tag="VWX48_000178"
     CDS             complement(58059..58649)
                     /gene="clpP"
                     /locus_tag="VWX48_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU9170902.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(58823..59452)
                     /gene="upp"
                     /locus_tag="VWX48_000179"
     CDS             complement(58823..59452)
                     /gene="upp"
                     /locus_tag="VWX48_000179"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU9170903.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLNLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(59541..60008)
                     /locus_tag="VWX48_000180"
     CDS             complement(59541..60008)
                     /locus_tag="VWX48_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU9170904.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(60027..60584)
                     /locus_tag="VWX48_000181"
     CDS             complement(60027..60584)
                     /locus_tag="VWX48_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9170905.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            60709..61554
                     /locus_tag="VWX48_000182"
     CDS             60709..61554
                     /locus_tag="VWX48_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9170906.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            61613..62788
                     /locus_tag="VWX48_000183"
     CDS             61613..62788
                     /locus_tag="VWX48_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9170907.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            62808..63263
                     /locus_tag="VWX48_000184"
     CDS             62808..63263
                     /locus_tag="VWX48_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9170908.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(63283..64037)
                     /locus_tag="VWX48_000185"
                     /pseudo
     CDS             complement(63283..64037)
                     /locus_tag="VWX48_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            64243..65578
                     /locus_tag="VWX48_000186"
                     /pseudo
     CDS             64243..65578
                     /locus_tag="VWX48_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(65618..66562)
                     /gene="manA"
                     /locus_tag="VWX48_000187"
     CDS             complement(65618..66562)
                     /gene="manA"
                     /locus_tag="VWX48_000187"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU9170909.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(66683..66979)
                     /locus_tag="VWX48_000188"
     CDS             complement(66683..66979)
                     /locus_tag="VWX48_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU9170910.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            67239..67813
                     /locus_tag="VWX48_000189"
                     /pseudo
     CDS             67239..67813
                     /locus_tag="VWX48_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            67810..68028
                     /locus_tag="VWX48_000190"
     CDS             67810..68028
                     /locus_tag="VWX48_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170911.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(68085..68369)
                     /locus_tag="VWX48_000191"
     CDS             complement(68085..68369)
                     /locus_tag="VWX48_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU9170912.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(68423..69358)
                     /locus_tag="VWX48_000192"
     CDS             complement(68423..69358)
                     /locus_tag="VWX48_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU9170913.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            69462..69905
                     /locus_tag="VWX48_000193"
     CDS             69462..69905
                     /locus_tag="VWX48_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU9170914.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            70021..70287
                     /locus_tag="VWX48_000194"
     CDS             70021..70287
                     /locus_tag="VWX48_000194"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU9170915.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            70284..70658
                     /gene="crcB"
                     /locus_tag="VWX48_000195"
     CDS             70284..70658
                     /gene="crcB"
                     /locus_tag="VWX48_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9170916.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDAVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            70652..70981
                     /gene="crcB"
                     /locus_tag="VWX48_000196"
     CDS             70652..70981
                     /gene="crcB"
                     /locus_tag="VWX48_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9170917.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            71100..71447
                     /gene="rplS"
                     /locus_tag="VWX48_000197"
     CDS             71100..71447
                     /gene="rplS"
                     /locus_tag="VWX48_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU9170918.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            71489..71560
                     /locus_tag="VWX48_000198"
     tRNA            71489..71560
                     /locus_tag="VWX48_000198"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:71522..71524,aa:Arg,seq:cct)
     gene            complement(71615..72421)
                     /gene="yidA"
                     /locus_tag="VWX48_000199"
     CDS             complement(71615..72421)
                     /gene="yidA"
                     /locus_tag="VWX48_000199"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU9170919.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYTTKTNDESGVAHAIRTWVL"
     gene            complement(72434..73738)
                     /locus_tag="VWX48_000200"
     CDS             complement(72434..73738)
                     /locus_tag="VWX48_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU9170920.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQCNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            73810..74187
                     /locus_tag="VWX48_000201"
     CDS             73810..74187
                     /locus_tag="VWX48_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU9170921.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDRQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            74277..74609
                     /locus_tag="VWX48_000202"
     CDS             74277..74609
                     /locus_tag="VWX48_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU9170922.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILDRYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            74621..76192
                     /gene="ffh"
                     /locus_tag="VWX48_000203"
     CDS             74621..76192
                     /gene="ffh"
                     /locus_tag="VWX48_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU9170923.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKVLAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTSEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(76387..77670)
                     /locus_tag="VWX48_000204"
     CDS             complement(76387..77670)
                     /locus_tag="VWX48_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU9170924.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(77924..78637)
                     /gene="rsmG"
                     /locus_tag="VWX48_000205"
     CDS             complement(77924..78637)
                     /gene="rsmG"
                     /locus_tag="VWX48_000205"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU9170925.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            78731..79291
                     /locus_tag="VWX48_000206"
     CDS             78731..79291
                     /locus_tag="VWX48_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU9170926.1"
                     /translation="MTWIILGVIALIVVFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            79293..80192
                     /gene="htpX"
                     /locus_tag="VWX48_000207"
     CDS             79293..80192
                     /gene="htpX"
                     /locus_tag="VWX48_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU9170927.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRIFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINAPKKG
                     GGVQKLFYTHPPISERIERLKQM"
     gene            complement(80341..81900)
                     /locus_tag="VWX48_000208"
     CDS             complement(80341..81900)
                     /locus_tag="VWX48_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9170928.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIICRMTE
                     HGLKLVNLEDL"
     gene            complement(82139..82456)
                     /locus_tag="VWX48_000209"
     CDS             complement(82139..82456)
                     /locus_tag="VWX48_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9170929.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYRPV
                     FEF"
     gene            82626..83168
                     /locus_tag="VWX48_000210"
     CDS             82626..83168
                     /locus_tag="VWX48_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU9170930.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            83168..83797
                     /gene="nth"
                     /locus_tag="VWX48_000211"
     CDS             83168..83797
                     /gene="nth"
                     /locus_tag="VWX48_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU9170931.1"
                     /translation="MILSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVVFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            84008..84529
                     /gene="pyrR"
                     /locus_tag="VWX48_000212"
     CDS             84008..84529
                     /gene="pyrR"
                     /locus_tag="VWX48_000212"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU9170932.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            84548..85471
                     /locus_tag="VWX48_000213"
     CDS             84548..85471
                     /locus_tag="VWX48_000213"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU9170933.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQIPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFSGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            85521..86600
                     /gene="carA"
                     /locus_tag="VWX48_000214"
     CDS             85521..86600
                     /gene="carA"
                     /locus_tag="VWX48_000214"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU9170934.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            86913..90089
                     /gene="carB"
                     /locus_tag="VWX48_000215"
     CDS             86913..90089
                     /gene="carB"
                     /locus_tag="VWX48_000215"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU9170935.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAVVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT        26446 a        19025 c        17383 g        27272 t
ORIGIN      
        1 tttagttgat tttatattac tattatataa tactttttta ttttagtcta gtataaatag
       61 cgagaaatat ctatcctatc ttctagaatg tcttccaaac gagaaaactc tcgtaaacaa
      121 agaggtttta gaggcctatt taccgtggga ctaaagttgt acaagaaaag tgcaaataag
      181 aaatctccag attaggaact atccgtgagt tctctagtct ggagattttt caatagactt
      241 cgttattgga cggttaccaa gttactcaaa gtacagattt gaagctgcag ataagattga
      301 cgaaatcact ttaatactaa atgaaaatca aaaagcaaac taagaagcta gcctcaggct
      361 gtacttgagt acggtaaggc gacgctgacg tgatttgaag agattttcga agagtataaa
      421 acactgtttt gaggtggtgg ataaatcggc tgggtaaaaa ctcaatctca ggagaaaatg
      481 aagtaaatct ccccacaact atagaaaaag atttgattct gctcctcaca caataaaatc
      541 tttttctttt attaaaaacg aatcgtttca cgtgttttct catatgaggt aacaaagcga
      601 ttggttacac caggctctgc cacttccaat gcttgagaaa tcttgtcaaa tgaagcgtga
      661 taatcaaatt ctttttcaaa aatatctaaa gcttcgttaa atgcttcttg aatgcgttca
      721 tcaaatgagc gatagcggtt agaatattgc aagagttgct ctgtcaaagt tgcatattgt
      781 acaatattat aagtttccgt ttctaaagct tccatatcat tcgttgcaat ttcaagaact
      841 cgggtaacag attcaatgtt aatcattttt tgttctaact caaccattaa atcctcggta
      901 ttattgcttg ccgtaaagaa taacttcaag aaagtttgtg gaatacctgg cagattgcgt
      961 ttttccatgt atcgcttgat agtatggaga cgattgacat aaacattggc cttttgacgt
     1021 gcattaatat catctttctc aatttgtgtc aggcgctcac taactgaaat ttgctcatct
     1081 tcaatatctt ttagttgagt ttgtaaatcc tcaagatttt cttcaagaac tgaataagct
     1141 tgggttggtt cttcttgatt tgaagttacc tcaacaatag ctgcctcaaa actctctaat
     1201 tctgtctgaa tacgacgaac atggcttgca gctgtctcag gaagtaaata ggtcttgttc
     1261 aaacgtgcaa tatcttctcc caataaagta ttattctctt tcatatgttg aaggtaagtt
     1321 ggaagagttg caagtagatt ttccactact ttctgagcag caatttctcg agtaaaaata
     1381 tcatacaagg cattgatttc ctcttgtgcc tgtccattct catattcggc attatccaat
     1441 tccaactgac gaatattctc ttggtttttc ttgaatgctt cataaagcaa gtggaaacgc
     1501 gcttcaatat ccgtttcaac aaaatgataa ttagcatcaa ttagtttacg ataaccggct
     1561 tccaaatcct gtaattgatc tggcaattct gtagaaagcg tcgtaaccaa ggctggaaca
     1621 cgatccacaa tatgacttaa ggccaaaatg tgattttctg tattatccaa aatcactgcg
     1681 gcttccacag ggtcacccga tgaattcaag gttacaaatt gtgaaaattc agattggata
     1741 ttttctaatt gtttttcaat ttcatccaag gcttgaccat actgttctga attttcagca
     1801 actctatgct gaagttcctc aaataaatcc gaagcatgaa gaacacgacc actattttta
     1861 gattcttgct tctctaagtc tgccaaagca ttgcgaattg ccgcaatatc ttcttcaatc
     1921 aaagtaattt gactctcaat ttggtcaatt tgatgactgg ccttgagaaa acgaaatgaa
     1981 tggttatagc cttctgcttc aaagagatta ttttcaatat cggcaaaaga gttgagagat
     2041 aaatcgaccc atttttgatt ccattcacgg aaagccactt gactttgtcc aatcaagtgc
     2101 atatttttta cagcttctac ttcatcattt actggaagat tgtatagttc ttcttttctt
     2161 tcttctagcg cctctaatct cccctcgttt cgcttacgta gaaagattgc cactacataa
     2221 gccagaacta aaatgactgc aattgcaacc attaaataaa ttagttgtcc attagacata
     2281 tcaaactcct tttttacttg aaacaatcgt aacaattata tcatattttt tagaccaagg
     2341 gaactacttc tccctatttt ttagacatca agtgtactat agacagcatt ttcttcgata
     2401 aactcacgac gaggctctac tcgatccccc atcaacatat caaagatttt atctgcttct
     2461 gcagcatcat ctacagaaac tctagccatc aagcgatgtt cgggatccat ggttgtttcc
     2521 cacagctgat gatcgtccat ttcacctagc cccttataac gctgaatagt cggtttggta
     2581 cgaccttcac tataacgggc taaagcttct tggagtttga tttcttgatc tgcacccggt
     2641 tggatatatt ctttaatctc gcttccaacc ttgacaccat agattggtgg ttgggcaata
     2701 taaacataac cagcttctag gattggtttc atataacgat aaatcaaggt taaaagaagg
     2761 gtacgaatgt gggctccatc gacatcggca tcggtcatca aaacgagttt ttggtaacgg
     2821 gctttcgaaa catcaaattc tgcgccaaat cctgttccca tggctgtgaa aagactacga
     2881 atttcttcgt tagctagaat cttatccata cttgcttttt caacgttcaa aatcttaccg
     2941 cgaattggaa ggatagcctg aaactcacgg ttacgaccag atttggctga tccaccagct
     3001 gagtctcctt cgacgatgaa gagttctgtt tcagcagggt tattagaaga acagtctgct
     3061 agtttccctg gaaggttgga aatttccaaa ccagattttt tacgtgtgac ttcacgcgca
     3121 cgcttggcag ccacacgagc cttggcagcc aaaattcctt tttctacgat acgtttggca
     3181 atctgtggat tttccatgag gaaatcggag aaggcttcac tgaagaggcg attggtaatc
     3241 ttgaccactt cgctatttcc caatttggtc ttggtttgtc cttcaaactg tggatttggg
     3301 tgtttaactg agataactgc agctaagcct tcgcgaacat cttcccctgt taggttgtct
     3361 tcattgtctt tcagtaactt atttttacga gcataatcgt tgataacacg tgtcaaggct
     3421 gtacggaaac cttgttcatg cgttccacct tcatgtgtat gaatattatt ggcgaaactc
     3481 atgacatttt catggtaacc cgttgtatac tgcatggcta cctcaactgt gatatcatcc
     3541 atctcaccgt ctgtatagat tggtgtatca aagattacat ccttgttctc gttgatatat
     3601 tcaacgtaac tagcaatccc accttcataa tgataatgct tggtttgttc caaaccttgg
     3661 cgcttatctg taattgaaat ttgaagaccg cgatttagaa aggccaactc ttgaatccgt
     3721 ttatttaatt tatcaaaatc aaagattgtt gtttcagtga agatttttgg gtccggtgtg
     3781 aagtgaacag ttgttcctgt tttatccgta tctccaacta tttcaagttc tgcgacaaca
     3841 tgaccacgac ggtattcttg gtaatgaatc ttaccatttt tgtgaacatg aacgtctaat
     3901 tgagtggaaa gggcattaac aactgacgac cccaccccgt gaagaccacc tgaaaccttg
     3961 tatccaccac caccgaactt tcctccagcg tgaaggactg taaagacggt ctcaacagca
     4021 ggacggcctg ttttttcctg aatatcgact gggataccac gcccatcatc cacaacagta
     4081 atcgaatcat ctggctcaat aaaaacttga atatggctgg caaatcctgc caaggcctcg
     4141 tcaattgagt tatcaacaat ttcccagact agatggtgaa gaccttcttt tgaggttgat
     4201 ccaatgtaca tccctggacg catacgaaca gcctctaagc cctctaaaac ttgaatttga
     4261 ctggcatcat aatcctgtgc ctgcagattt ttgatttctt ctgtcatctt attccttttt
     4321 cttatatgtc taatacttgt cttaaattca cgatactggt aaacaagtgg gtatcaagtc
     4381 ctgcagcttg acctgcttcg atatcaatcg gccgatcacc aatgacaaga ccagagctaa
     4441 tctgatactt ttctcttaaa taaagcatgg attcgggatt tggctttctc ttaaagcctg
     4501 agctagaagt caccacttct gtaaaataag ctgctataga gggtttttct aaaatttcca
     4561 aaacctgatc gtttcgatga gagaccaaaa aatgacggcc accttgattt gaaatgtctt
     4621 ccaataggtc agaaactcct tcaaataaaa tcgggtgttc aagctctctg gcttcatttt
     4681 ccttgtactt ttctaaaaaa ttctctaaat tgggagcgaa tgtctcaatc gcaaaaggag
     4741 tagaaacctt taaagcttga tagacactgt catggtcttg tgtgatacca tacagtgcca
     4801 atgtttcaac aaatgcagct gttgaagttt cataattatc cagtaaagtt ccacctaaat
     4861 cccagatgta atcgtgatat ttcataccct tcattatagc atttttttat gaaaaaagcg
     4921 atgatttccc tgagttttcc acataaaaaa cgagagaata actcccgttt tactgatttt
     4981 taccaaagac atctcgatag agcattcctg ttcgtaaact ctctgcgtcc cctcctagtt
     5041 gctccaccaa ctcgtaggca aaggcaaggg ctgttgaagg accccgactg gttgtcaact
     5101 gaccatctac cactactgtt tccttgacgt agtgaccatc aaggatttgc tcttgaacgc
     5161 cgtcataaca agtgtatcgc ttatttttca atatctctgc ttgattgagg gcaattggtg
     5221 ccgcacaaat ggctgctagt ttcttccctt cttgctcgaa gctttgcaat tcttgaatca
     5281 aggtctgatt atcacgtaaa tgtgcagaac caggcatacc tccaggaaga acaatcatat
     5341 catagtctga taaatttcca tcaaagacat gatctgctct tacttggatt gcatgcgaac
     5401 ccgttacttg ctcttcaaaa ccaaccatat cacatgtgat attggctcga cgcaagacat
     5461 ctacaactgt caaggcttca atttcttcaa agccctgagc taacataact gctactttta
     5521 ccatgatttt ctccttattt aatttgtttt aatacaacct ttttccgttt gaatgggact
     5581 tttccgctct tttcttcagc tagattagtc tggtaactca tcgataaaag caaaccaaca
     5641 ccaatcagat tactgataat agctgatccc ccttgcgaaa tgaaaggcaa gggaatcccc
     5701 gtcaaaggaa gtagtccagt cacagcaccg atattctcaa agatgtggaa gagcaacatc
     5761 ataatcaaac ctgtggaaat ataagtgtag aactggttat ttgatttaag agtaatcttc
     5821 aacatacggt aaatcaacat gagatagagg gcaataacca ggacagagcc aataaagcca
     5881 aaatcttctg caataaccgt aaaaatcata tctgactctc gaactgggat aagcagattc
     5941 gaagcattaa atccctgacc aaataagcca ccactcccaa tggcaatctg cccttgagcc
     6001 tgctggtaag tcgttgtttg ggcaaactca aagggattga gccaagccaa aatccgattg
     6061 atttggtagg tcggcattcc aatctggtga agaaaagctc gtccgtcctt gctaataaag
     6121 atagctaaga aaccagcaac tcctgttaca gcagtcacaa atactgggat aataattttc
     6181 caagaaaccc ctgataataa aacgattcct gagaaaatgg ctacaaaaac caaagccgtc
     6241 cccaagtcac tttgaagtgc taaaagaact aggactggaa tggtaaagag aatcatccag
     6301 aaaattaaca aaaagtccag cggaaccgtg cgtctccatt ccttatgttt ctttgtaaat
     6361 tggacaatga cacgagccaa catgaggata taggatatct tcataaattc tgacggttga
     6421 aatagggtaa ttccatttat tgatacccag tttttggcac ccgttgatgc aactaagctt
     6481 ggattataaa atacaatcgg caagatcata agtcccaagc ctaaaatata tagaaagggg
     6541 gtcaccttcc aaagaaattc tgtattaaag agcatgacca caaaaccaat cacaagcccc
     6601 aaggcaatcc aggcgacctg ctgccctaaa atgggcagaa tattattggg gtaatcatga
     6661 ctaacggcta tatagatagc caccacaccg atgaccagta gaaaaaatac tggcaagagc
     6721 aaactgtaat cgactcttga gtcgagagaa cgtttcatat atactaacct tatactttca
     6781 tacaatacta tttatcaaag ttcattaaaa aatctatcaa tagcctcgtc aacttcggat
     6841 cgagagatgg ttttaacagt cgcttcttct gctagagatg ctactatttg tttgccgtat
     6901 cgttttccga cgattctcct atccaaaata agagttaagg aacgttggta ttcacgtctc
     6961 atacttcttc ccaaagcctg ttttaaacga ataatggcca ttggcaattg ataatcataa
     7021 aaggcatttt tcccttcttg attcagttct tgattaatct ttttcgtcaa gggttcttga
     7081 ggattttgga aaggaagcct cggtacaact tgaatcacaa aaggatggct tgaaaaatca
     7141 actccctccc agaaacttgc tgcaccaagc aagatttgtt gttcaccttt ttcaaagcgt
     7201 ttctttagct gatgaacatc cccattttta tactgggcca agtggctaac tgtaagtaaa
     7261 tccgatactg ctagaagcat gtctttagcg gtaaagagaa ccaaaatcgg ttgctggaaa
     7321 gcttgaattt ccactagtaa agcagctacc tctctggcat agacttctaa ggaggtttct
     7381 gttaccagag ggaaatcttt gaccatgacc acttcttgtt cctgttttcc ccgagattca
     7441 atcttgacaa atttagcttc aggatagcct aaaaggtctg ccaaagaaac cctctgacta
     7501 atctcaagag tagccgatac tcccaggact tggcaactct caggaagtaa agaggacaga
     7561 agagtacggc ctgattttgt agaagaaatc tgaattttct tttgactcgt ttcagttact
     7621 tcaagccagt aatcaccttc agctgtaaaa tagcgaacca gctcatcaaa gccttctact
     7681 tctaattctg aaaaatactg atggagatta tccagagaat ctaagatatt tttcctagat
     7741 ttgccagact gaaattgttc tatcaagtag agacactcaa agcgaatact ttctagtatc
     7801 cgttgttgaa ccctgttttc ttctcctact aaagccttat caattaaatc gataatagat
     7861 tgtatatcgt aggtctcttg aagcagattt tctagagcta acaaaatctt ttggacttca
     7921 tcaataatca gtaaacggtc actgacaaat tcaggattat cttcaagtct ggtcacgaga
     7981 taggcatgat tagtcactaa aagcttgcaa gtctctgccc tttcttgact acgtttccaa
     8041 aaatcttccg tcacaaataa gctatgggat gataaattcc catcatgacg aaggtctgct
     8101 agaaaatgtt ggtaacggta gagttgcccg atttcatcca aatctcctgt ctctgtctca
     8161 gtaagccaga ccaagacttg cattttaaag cgtctaaata agcgattttc atcattttcc
     8221 tgcaaggaat gataaaaggc atccaacttc agataatttt gtggtccctt taagctatga
     8281 atatctgtat ggaacacttc cttgagacgt ttaccttctt cttccatgat ttgattttga
     8341 agaatctttg tcggaacact aagaacaatt tgtcgctctt tggattgaga taaagcgggt
     8401 aagagatagc cataggtttt cccaatccct gtcggcgctt gaatcagaga gacaggttca
     8461 tctttcaata gcaagccaac ctctttagca aaactttctt gttcctccct cacttcaagg
     8521 ttcaacagag aaatattttt agaaaagtct tgagatagtt ttcgtagctc cagagaagct
     8581 gccgttttct taaaatacag accttgaact tggaccaagt ctggagaact caggatagat
     8641 tggttgcgat aagtttcctc aataaccagg taggactcat ataggagagc gtcagccatt
     8701 tccagcaagc gttccaagag acctttagga agctgggtca tcttttcccg taaaaaaaga
     8761 agtaattctg ctgtagcttg ggcatctgaa agggctgtgt gtgcgtgttt aagaggaatt
     8821 cctaattctc gacacaaaat cggcaagcta tatttttcca gttcagggaa aaagacctgg
     8881 gccaattcga ccgtatcaac acgagggttt cttagctcat agccttcaaa aaataaattt
     8941 tccgccaaga gattagcatc aaactgaaca ttatgggcta caaaaatccc atcctccacc
     9001 aagtcaaaga tttttctggc aacttgcgaa aaatcaggtg cttgcgccag acgttggtct
     9061 gtcaatcctg tcagttcttt gatatgagca tccaagggtt catgtggatt gacatccgtc
     9121 gtatagtgat cgacgatttc tccatcctca atcacgacaa ttcccacttg gataatttta
     9181 gccttactac ctgtgctagt tgcctctaaa tccaccacaa catagcgatt accaatcgtt
     9241 ttcattataa aaaattatac caaaaaaagg gccatttggc acctgcaaac ataggataat
     9301 tttcaaactc aagaacacta cttttcttag aaatcccatc gaatagagca ttctagcctg
     9361 ctgatttttt taaaatagtg aagaaatacg aaaaattgag agaagaaatg ttttcatctt
     9421 ccttctctca acgaatcatg tattttattt aaccatgtca ggatcgtagt cataaaatcc
     9481 tgtatcaagg aaacggtttt tagggtgaag tttacgaact tcttcatcca gcaagaaggc
     9541 ttggtcatgg ctaaagttgc cctcttgaat caagctacgc gcttggataa agagttttgc
     9601 aatctcaaca aagttctgac caggagtgta gagcccttct agtttccagc gagtaaagcc
     9661 atgctccacc aattctgtta atttgatcat caaatcaagg tcattgttgg caaagatatg
     9721 ggtcccatga ttatcttcaa aaatggaata gtggctctct ggatcacttg gctcagccaa
     9781 gaagaggtca cgtttatgcg tcttttcatc atcgatatgt gtaaagttat agtagttttg
     9841 caagagtgga cgtttagaat gatggatgac gctagcaccg taaaccaaaa cttcagcagg
     9901 aatttccaaa atctctggca ttttgaaaag ttcagctgat ggaatttcac gcgccaaaac
     9961 agcctcagat gcgccagcct tttgtcccca gaagttaatc tgacgactgc tagttaccat
    10021 ggttgaagca tcgtagatgg tcttaaatga ataaccatcg cggttaacta cgtaaaagac
    10081 gcctgcatcc ccaatcgtaa tatagtctgt cttgatttct tccaagaagt ctaagaaagg
    10141 cttgatacgg tccatcatat cttggtgcat gagagcattg accgcaacga gcaattcctt
    10201 accagcatca tgaaccaact tagcgatttc acgtaattgg tcataactaa aggtcgttgg
    10261 cagacgaagg ccaaaatctt tctcaccgac atagatacgg tctacgccag cttcgagtag
    10321 ttgttcaact tgttcaatac tttcagcagt tgctgtaatg acaatctttt ccataagaaa
    10381 aattatacca catttctcca aaatcatcca tgctttgaaa atgaaaaggg actttattct
    10441 ttttgtaacc tttctgtaat aattttctgc cgaaaaaatg ataaaatagg tatgtactgt
    10501 taaggagaga atcatgcccg taagaaaatt acaatcctat gaggtagact atcaagaaga
    10561 attaaaccag cagcttcctc attaccaagc ttatacacct gaagcgcaat ctgatgccaa
    10621 tctcaaggaa atcctatttt ttattaatat cgctgttttt tgtatctgta ttgctatctt
    10681 tagttttatc tttttagcat taaaattatc aactgctctt gcctttgccg cagcaatcgg
    10741 attcagctta cttgttttaa aagttcaacg gtctattatc aaacgaaaac gtagaagata
    10801 aatccaaaat atcgccccaa ttggagcgat atttttattt tttcttttta gatggtgtct
    10861 gaatggcaat cttcacttca aagattgttc ccttgggttt attatctttg acagtaacag
    10921 ttccttttag agcatctaca atttgcttgg ctagggataa tcctaaacca aaaccacctt
    10981 tttgccgggt tctagccttg tctactcgat aaaaacggtc aaaaattttc tttttatctt
    11041 ctgtcgaaat accgattcca ttatcagaaa caagtaaata aagattgcga tcggtcgccg
    11101 agataagaaa atcaatttca ccatcctcct cagtatactt gacggcatta tcgaaaagaa
    11161 tggtcatcag ttgtttcaga agaagctgat ctgtgacaat tgttcgatgg atacgatttt
    11221 caaaacggaa gacacgatta ttttccgaag caatcatctc atagtttgtg aaagttgtat
    11281 taaaaaagct agttggaact tctgcaagct ccggcttaat cccatcatct ctccgagcta
    11341 agttcagcaa gcttgtcgtt aaaaaacgca tatttcggac ttcttccaaa ctcgatgcaa
    11401 tgctttcgct cacatccata atggtagctt ctggcttacg aaaaagggtc tctaagcgat
    11461 tttgcaaaac tgcgagtgga gttcgtaact catgactggc attttccaca aaagactgtt
    11521 gcttctgcat actctcaagc aggggcctaa cactgaccct agctagatag agactggcaa
    11581 gtaaagacaa aatccagaaa ctagccatca cgaccacaat caattgctca tgcttttgac
    11641 tagcctgctc caactgactg gtattaatca agacagcagc atacttgata ttggttgaaa
    11701 ccgaactaat attggtctcc atcaaaatca cacgatagat ttcttcctgc ccatagctat
    11761 taaaaacctg aatctggtag atatgtccta gttctttctt ttctaactta atcttatcca
    11821 agcccaaaaa tcgatttcca gaaagaagtt gagtaaagtc tttatcaaag agaatgactt
    11881 ccgtattgga actgacatta ggttttattt ctactttact agcgtccgcc ctagcatttt
    11941 ctaaatcttt aatctcttct gttgccctat ttatagccag ctgaataact gcttgaggat
    12001 tttcactcag tccatgaagc ttatcgtcca ccgaagtata aagactcgaa tgcatgactt
    12061 gtaaaataat cagagtcatt gtagaaaaaa tcagggtgaa gacaccgaag ttgcggataa
    12121 aataactaaa gtcatccgca taccatgttt ttttaagttt actgaacatc ttttaaaaga
    12181 tacccaacac tacgcaaggt ttgcaaattc tctgcaaaag tggttccctt taatttctta
    12241 cggacttttg aaacatagac ttcgacaacc gaaatcgttg tatcactatc aaatccccat
    12301 agacggtcaa aaatctgcgt cttaggcaaa atcacatttt gattttgaag gaaataaact
    12361 agtaaatcga actctttccc cagcaattcg acaggagtat cttcaacttt aacggtattg
    12421 gttgataaat taaccacgat attcccataa gtcaaggtgt tttcattaaa cttccctgaa
    12481 cgtttgagaa gggcctgaat tcgcatttta agttcttcta ggtagaaagg tttggtcaga
    12541 taatcatccg ctcccagttc aaatccatgt cccttgtcat ccaaactttc cttggcagtc
    12601 ataatcagaa ctggtgtcgt aattcccttt tcacgcaatt cttttaagac ttggaaacca
    12661 tttttttctg gcaacatcaa atccagcaaa atcaagtcat agacaccact ctcagcttcg
    12721 tagagacctt cttctccatc aaatacctgc ataacatccg caaaatcgtc taaaaagtca
    12781 aatactgaat ttgacagacc taggtcatcc tcaaccaata agatttttat catgagaaac
    12841 tcctccttat taaaactatt ataccaaatt tgccttaaaa aaaactcaac tctctgcatt
    12901 ttacatgaga tagctgagtt ttctttttat tttaggctta tttatgcatt tccgtattga
    12961 agaacaactg cttcgactgc agctttttca cggctaatca agtcaacacg tgctgcaatt
    13021 tccttgattc ccataccgat gttacggcta agagcaaggt cagaaagttg cggctcaaag
    13081 aactccttgt attccgccaa gcgttgctga gtcttaaata catgagcagg aaggataaca
    13141 aagctatcaa agctcatatc tcctccaagg gctgccttaa tccaagccca gttttcacgc
    13201 gcccaagacc aagctgtttt ctgagttgct tgatgagcta ggaattggta ataccaagca
    13261 gacaagtcct gtggtttgac cacaaatttg tccttccaag aagtaatcaa gttttggata
    13321 ttatccgcat ctgtactgta tgcaagagct gctgccaact ggcgtttaaa gacagcatct
    13381 gttgcgtgag tataagtatc aagataaagt gctaacaagt ctttagtctc atgatgtttc
    13441 atctcattaa tcagaacttg tgaacgaata gctgctggga gttctgcaag attctccttg
    13501 tgtgttgcga agatttggct agcgacttga cgagcttctg catcatttga gcgaatcatc
    13561 atcgaaacag ccagctgacg aaccaattca tcctcatctg attctccgtc tttagcttca
    13621 aaaccaagac ggtcatagtt atgacgagcc aatttagcaa ccagtccttt gaaggctgtt
    13681 tcagcatccg ttccttcatc aataaagcgc tcaagggctg aaatcacttg agaaacagct
    13741 gaaaccacca gataagactc ttccttagca agtttatcaa gaactggaag caagtctgca
    13801 taagaaatgt gccctgcctc agccaacaaa cgacgttctt gaacaatttg cagtttgctt
    13861 gtgttatcaa gtgtctctag ctcagcaaga acagcttcta acaagtctcc ttgatagtcg
    13921 gtaatatagt gggcagtatt ttcagtgttg agacgaagag ctccttcatt ttcagcaaga
    13981 agagctgcgt agccagggat ttcgatactt tcagtttcga gtgtatcagg caagcctttc
    14041 cagttgctat tgaggggcac cacccagaga cggttcttgt cttcgttctc accgatgaag
    14101 aattgttttt gtgaaatctt caagacatca ttttcaactt tgacagtaag aactgggtaa
    14161 ccaggctgtt ccaaccaaga atccatgaag gctgcgacat cacgtcctga cgcttgacca
    14221 agggcatccc aaaggtcact accaatggtg ttgctgtatt ggtgtttttc aaagtaggca
    14281 tgcaaacctt tagcaaaatc agcatctcct agccaacggc gaagcatgtg catgagacgg
    14341 cttcctttgg catagacgat agcgccgtca aagagtgtat tgatttcatc tggatgttta
    14401 acttcgacgt ggacagactg aacgccatca gtagcgtcac gttcaagagc aagaggtact
    14461 ccacctgttt ggaaatcttc aaagatattc cagcttggtt cgatggtatc cacacagacg
    14521 tattccatca tattagcgaa actttcattg agccaaaggt catcccacca tttcatagtc
    14581 acgaggttcc caaaccattg gtgagccaat tcatgggcca caacaagggc aacttgttga
    14641 cggctagcaa atgtagagtt ctcatcgaca accaagtaaa cttcacggta ggtcacaaga
    14701 ccccagtttt ccatagcacc agctgagaag tcaggaaggg cgatgtggag agattgagga
    14761 attggatact taactccata gtaatcttcg taaaactcga tagagcgaac agcgatatcc
    14821 agtgagaaat caagatttga aagtggatgt gctttggttg agtagacacc taccagggta
    14881 ccatttttag ttttagcggt caccccttgc aaatcaccag caacaaaggc caacaagtaa
    14941 gaagacatgc gaggtgttgt ctcaaacttc cagatacctg tttccttacg gttttcaaca
    15001 tcgatttctg gcatgtttga caaggccaat tcaccttctg cttggtcaaa gcgaagagag
    15061 aggtcaaaag ttgctttggc ttcaggctca tccacacatg ggaaagcttc gcgcgcaaaa
    15121 tggctctcga actgagtaga caagacctcc ttcttgactc catcaactgt ataataagaa
    15181 gggtaaatcc ctgtcatgtt gtctgtaatt ttaccagaaa aggcaagaac caattcaact
    15241 tgaccagcct cagccaattc gatatgaagg gcttcattgt catggtcaac tgtaaatgga
    15301 cgagcttgac ctgcaacttc tacagaggtg atttccaagt ctttttggtg gagggagatg
    15361 cggtcactct gtgcttgacc agtgatggtc actttcccag aaaaagtctt ggtctcacga
    15421 ctcaaatcta aaaataaatc ataatgttca ggaacaaatt gcttaataaa atgttcaact
    15481 gcttgcatag ttttctccta ttctaagttt aagagctgct gctcttcttc aaacaaactt
    15541 attatatcat attttgcttg aaaaaaaagg attggacagc gatttccaaa actttcttcc
    15601 ttctaatagt ctacagtggg tagaccttgc gaaattcttc taaaacaacc ttgctttcag
    15661 atgtaaaagt cagccctact tcacccaaac agtctgtgaa aaagtcctca tgaacctggc
    15721 gccaataggc aagtgatttg tctccctcac cttccttaaa ggcatgttgc gcagaaactt
    15781 gattgaagag ttcaacagaa acctttgtaa tttcgacaat gcagacagac tgattttgac
    15841 tatctaaaat gatatcgaag gtccctactt ggggaagtgg ttcgtcttct agtacataga
    15901 ggtcataggc tgatgctgtt gctgtctttt ctcctttaaa caccaaatcc gctaaaagat
    15961 ctggttcaac tccaaaagcc caagcatcga tttcatctcc gatcaaagga ttgatttgct
    16021 tgtatttatt ccacatttct tgcggtatca tgggtactcc tttgtaattt tttactttct
    16081 tcttttatgt gtttaagatg atctggatgg tcaatctcta aatcaaaaat ctctggaata
    16141 gaactgtagt ggataatgca cttgataccc aactgattca ttttttgtat gaaagaagta
    16201 ttcagatagc ctgctacagc aaaatcaatc ttgttctttc ttgctttatc ctgcatatct
    16261 cttagcatat ctaacattat tggactttcc atatcatgcc attgactgtt tctcatagtc
    16321 gcaaaaacaa aggaagtcaa atcattcatt ccaactacaa tctttgaaat gcccgtttcc
    16381 agtatactag ataagtcaaa atacgctgac ggtaattcaa tcatcgttcc gactttccca
    16441 gtaaaaccct gctgacgcaa tactgtaata gcttgtttta attggtcgtc atcattgaca
    16501 aaaggaaaga taacagatag attggggttg gtttgataaa cttctgtaac gacatgtgct
    16561 tcagcctgaa attcatccaa acacgccagt aaacgcctgg ttcctctata gccaaacaag
    16621 ggatgccctt cgtcaaaaaa ctctctagtc cccactaaac aattggcttc tgtattcgtt
    16681 aattcagaaa aacgatacca aacttcttca tctgagtaca gggagcagat agtctctaga
    16741 taatctttta caaattgctg acaacttgct aatatgatgt tttgattaag ctctctcaac
    16801 aaatattccc cacgaatcat gccgacgtgg tgaaatagtt gaggataaat tttttcaaga
    16861 attttttcgc cactaagggc aagttgattt ctcatagcca ttcacctcgt cttaaaagat
    16921 acaatatcat atataattat atcaaaattt cctctagttc aaaagcttca taaggttcag
    16981 ataactcata tcctaaaaat tctgctactt ttttggaagc ctcattatga gcatcccaaa
    17041 gtggaaacat atctctattt aaactctcta gaatcattgc agcaccaagc tttttagcaa
    17101 atccatttcc ttgttcgttt ggtctagttg caacttccac ttcaactgct ttacggtaaa
    17161 ctaaccctga ggaaatccca gcaatcagtt cattattttt aagaatcaca aagccaaatc
    17221 caccttttaa aacaaaatcc tgataggact caaaatcccc ctgtaaatcc tgtgaccatt
    17281 cttccgtaga aaagcagtta taaatatgat tatcaatagg cacaatattg taaccttcct
    17341 ctaaatgagt aactagatta tttaaaaatt caacttgaaa atttgcctta tctttaaaag
    17401 aatagcgagt aaaagaattt agccccactt ttcgatgcag aaaatcttgc caattagtat
    17461 tttctgaaat aataatctta taatctaaac catattttct aacaaaatct tcccaaaatc
    17521 tggaatccaa ctcccctgct aggtatagaa aattcccaac atcataaaag cttgttgtcc
    17581 tatcattgtt tcggtagaca gttccaattt gagatttaag accatagaga accatatttt
    17641 tcttccatgt tttaaatagt tccattatcc ctctacttca ccttccaatt catgtaagaa
    17701 gtcttgtcca gttctggcaa tcctaataat tcagacttaa ccttcaagac taatggcgat
    17761 gcattttctt ctgtaatctc ttgaatatcc atccaaatat atccaagtga atcattcgca
    17821 ccatcagaca cagcttccga aatcgtaact tgaggtgcac tctcattcat ttcaacatca
    17881 tacaaggcta tgacatggtg aaccataaaa ttttttaact cttccctgac gaaaacatcg
    17941 tagattcgag gattagagta gcttctaaca gtaaatcccg tctcttccat aacttctcta
    18001 gtcagcgttt ccgtcagtcc ttcaccaagt tgctgactgc ctccaggtag atcataccga
    18061 tgttgataag ggcctctcgt tttttcaatg caaagtaact ttccattttc aaagcaaaca
    18121 cagtagaccc caaagtgatt tttgatttcc atccaactcc tcctacttca aagaccagcc
    18181 accatctatt gtcagaattt gtccctgcat ggcagatgcc tttccactgg ccaaaaagag
    18241 actgacttct gccacttcct ctggttcaat ccagcgcttg attggtgttt cactagccac
    18301 ccagtcagct aagccacctg tctcaaaatc cgcagcggtc atagctgtct tgactgctcc
    18361 tggagcgata ccaaagacct gaatcccagc ttcagcatag tctagagcca actgcttggt
    18421 gaagccagcc aaggcatgct tggatgaagt ataggcgtga ccacctccac ctgctaggct
    18481 agaagcaatg gaacacatat tgatgatgat tcccttttta ttttccagca tttgtgtcaa
    18541 ataataccga gtcaactcta ctggaataat gtagttgatt tcaaaaatct cttgaatgtc
    18601 ctgcgccgtt tgttccaaca gtggtttgta atcatccaaa actccggcag tattacacaa
    18661 aacatccacc tgagggcacc agtcaaaaat aggttccaag tccaaggtca aatctctctg
    18721 taaaaagtga aaatcaccct ctaagagtgg cttttcacct tggtcaactc cataaacttg
    18781 atagcccttc tctaaaaaga ggcgagcttg agccaatccg atccctgaac tcactcctgt
    18841 aatgagtaca cgtttagtca tgcacttcta cccaatccgt tgccaaaaca tcacaaactg
    18901 tcgggctcca catggaaaaa ccttctcctt cgccagaaac gttgattagg aaataaggtg
    18961 tcatttcaag tgcaagccca ttttgctcga tggtatcaaa gagttggaca tagttttccg
    19021 cacctcccca accagttcgt acatattttc tcttagcctt taacccaggc aggatctctt
    19081 caaatgtcat gtttttctcc tttaattcta cattcttcat ttaattatag caaaaaacca
    19141 ctttatacgg ctttttgact gtgagttatt caaacctgct actacttacg gcaaattatt
    19201 ccctgcagca agataaattt cataccattc ttttcttgtt aagctaaagt ttgccgctcg
    19261 gctaacttct ctcaagtgct taggatttgt tgtacctacg actgcctgca tttttgctgg
    19321 ataacgcaat atccaagaaa tggcaatagt tgaagaggtt actccatatt taatagctaa
    19381 acgatcaagt acttgattta aagcttgaaa tttctcattt ccaacaaagt tccctttaaa
    19441 atacccgaat tgcaagacag accatgcttg aatgaccaca tcgtgtaatt tgcaatattc
    19501 aaaaatgctg ccatctcgca tagctgcttg actatcttcc atattaacat gaaaagctga
    19561 ttcaaatcct ggagtaaaag ccgcactcaa ttgtagctga ttaacagcta acggctgctt
    19621 gacatctttt ttaagcaact ccatcatcat aggattttga ttagaaactc caaaatctcg
    19681 aactttacct tgtttataaa ggagatcaaa ggcttctgct acttggtcag attccatcaa
    19741 agcatctggt cgatgaagga gcaagctatc tagatgatca atcttcaatc tttgcaaaat
    19801 accgtctact gattttataa tatagtcctt agaaaaatca aaataggtaa attcttcaat
    19861 gcgaatgcca catttggact gaatccacat cttttctctt aaatctggac gattttttag
    19921 gacaagacct aacagttctt cacaacgacc acgaccataa atatcagcca agtcgaaggc
    19981 attgattcca acagaaagtg ctgtttctac aagctcttca acttctttta cagacttatc
    20041 ttttattctc atcattccga gaacaatttc tgataattct ttgtcatctt gaccaagagt
    20101 tatgtatctc atcaaatttt tctcctttaa tttctaacat tcttcccttc attataacaa
    20161 aaaaccgctt tgcaacggct ttttgactat acttcactcc attttatctt cttaaaccca
    20221 cggaacaaga caaagattcc aataaagagg acagctaaag gaataacttt tgtaaggaaa
    20281 acatttgaaa ttcccatcca ctcataataa cggagcagag aacccaccac aagatgggca
    20341 ataatcatac tgacaaatgg acgaaagacc gcttctttcc aattccaaat accgataact
    20401 agcgaaatcg taaagacaga caaactatcc cagggagccg gaatataaaa ggctccttct
    20461 tgtatgaagc ttgccattcc tacatatcct aaaacaacta gaagaactat agtcccaaca
    20521 acaatgtaag tgccaatttt cattttagga gaatcttgga ctaaacttct tcgtaaaatt
    20581 gtggccacaa gtccaaatcc aatcagaaaa ataagaagtt gccctaaaaa tgtgagcaaa
    20641 ttgactgtta agagaggacc tttagaaaaa tcacttagta gttgataata acgtaatacc
    20701 gccaggacaa gaattggcgt caaaagggac tctttgatag aactgcgagg tgctcccttg
    20761 agaatctctt tcattatttt tttaggattc ttacctagat aatcctctgc actcatgcca
    20821 tctcgttctg cttctgagaa atctagcatc atcaaataga tctgctctct gagatagtct
    20881 tcatcataga gaaatccagc aagattaaaa ctttcccaca actcctcaaa atacttttga
    20941 ttctcctcag aaaactcatg tagcaaagcg cttgtttctt cgtaatactt cattttcttc
    21001 atggtttaac ccccattctt aatcccttct actttttgac tcaaatcgtc ccattgttgc
    21061 caaaagactg agacacgctc ttctccttct ttcattaatg aaaaatactt ccgatctgga
    21121 ccatctggcg acgggcgcat gtcgcctctt atccattgat ttttttctaa cttttgcaac
    21181 aaaggataaa tagttcctgg aacgatagta tcaaatccag cctctcgcaa agtctgaacc
    21241 aactcataac cataccgctc tttttgacca atcatatcca agacacaacc ttcaagaaca
    21301 ccttttaata gctgagtttc tttcatcact tctcccttct aatctatttt gtaataccta
    21361 ctagtaactt cacctatagt atatcacttc tacactagtt tgtaaagcat aatagttaat
    21421 actcttcgaa aatctcttca aaccacgtca gcgtcgccct accgtatgta tggttactga
    21481 cttcgtcagt ttcatctaca acctcaaaac agtgttttga gctgacttcg tcagtttcat
    21541 ctacaacctc aaaacagtgt tttgagctaa cttcgtcagt ttcatctaca acctcaaagc
    21601 agtgctttga tcaacccgcg gctagcttcc tagtttgctc tttgattttc attgagtata
    21661 aataaaaaaa cagaactagc ctgaactagt cctgtctact tttacccaat cacacttcca
    21721 tttggtacag ctggatcaac tgtgagaagg gttaatttgc catcatgttc agctgagaga
    21781 atcataccct ggctgacata ttttttcatc attttacgtg gtttgaggtt agcaacgatt
    21841 tgaactttct tgccgaccaa ttcttgttca tttggatagt attttgcaat tcctgaaaga
    21901 atctgacgat cttctccatc accagcatcc aagcggaatt gaagcaactt atctgaacct
    21961 tctactttag acacttcttt gacttctgcg acacggattt caaccttgtc aaagtcttca
    22021 aacttgattt catccttgtt tagtttgagc tcaacttcgt ccggattcca ttctttttcg
    22081 actgctggtt tattgccttc catttgttcc ttgatatagg cgatttcttc ttccatattt
    22141 agacgtggaa agataggtgt tcctttggca actacagtca catctgctgg gaagtcagcc
    22201 aaactcaagt tttcaagact agaaacttct tccaaaccaa gttgagtcaa aactgcacga
    22261 ctagtttcca tcataaatgg ttcaatcaag tgagcaacta cacgaatgct ggctgccaag
    22321 tggctcatga cacttgccaa ttggtcacga agagcttcat ccttgtccaa gacccatggt
    22381 gcagtctcat cgatgtattt attggtacga gagatcagag tccagactgc ttcaagcgca
    22441 cgtggatagt caactgcttc catgtgtgta tggaagtctg cgattgattt ttctgcaacc
    22501 tcagcaagaa catgatcaaa ttcagtcaca ccttctacat aggcagggat ttgtccatca
    22561 aagtacttat taatcatgga aaccgtacgg ttaaggaggt tcccaaggtc attagccaat
    22621 tcatagttga tacgaccgac atagtcttca ggagtaaagg ttccgtctga accaactgga
    22681 aggttacgca tgaggtagta acgaagtgga tctagtccat aacgctctac caacatttca
    22741 gggtaaacga cattcccttt tgacttagac atttttccgt ctttcatgac aaaccaacca
    22801 tgggcaatca aacgatcagg taatttaaca tccaacatca taagaaggat tggccagtag
    22861 atagagtgga agcgaaggat gtcttttcct accatatgga agactgttcc attccagaac
    22921 ttgtcaaagt taccatgttc gtcttgagcg tagccaagag ctgtcgcata gttaagaagg
    22981 gcatcaatcc aaacgtagac aacgtgtttt ggatttgatg ggacaggcac tccccatgta
    23041 aaggttgtac gagataccgc caaatcttcc aaacctggct cgatgaagtt gcgtagcatt
    23101 tcattaagac gaccatctgg cgtgataaat tcaggatgag ctttgaaaaa ttcgaccaaa
    23161 cggtcttggt atttgctaag gcgaaggaag tatgattctt cagaaaccca ttcaacctca
    23221 tgacctgatg gagcaatacc accagtcaca tttccagctt catcacggaa aacttctgcc
    23281 agctggcttt ctgtaaagaa ttcttcgtct gatactgaat accaaccaga gtattcaccc
    23341 aagtagatat catcttgagc aagtaagcgt tcaaagacct gtgcgacaac tttttcatgg
    23401 tagtcatcgg ttgtacggat aaatttatcg tatgagatat ctagtaattg ccagagttct
    23461 ttaactccaa ccgccattcc atcaacatag gcttgaggtg taataccagc ttcttccgct
    23521 ttctgctgga ttttctgacc atgttcatca agacctgtca gataaaatac atcgtagccc
    23581 atcaggcgtt tgtaacgtgc taggacatca catgcgatag ttgtgtaggc agaaccgata
    23641 tgaagtttcc cagatggata gtaaatcggc gttgtaatat aaaaattttt ttcagacata
    23701 atttttcctt tccaggcaaa tgaaacctgt ttttctaaca cttcattata tcacattttt
    23761 aatgaatttc gatagggaaa tccatacaaa aacaagatag acgagtgtcc atcttgttga
    23821 tctcattcat aacgaagggc ttcaattgga tcaagtttcg atgccttgtt ggctggcaag
    23881 actccaaaaa tcatacaaac actagccgaa actgcaagac taaatagggc aactgggatt
    23941 gatactccaa cttctatacc ttctattaaa ccttgcagta acaaacctgc taaggcagtt
    24001 aaaccacttg caattgtcaa gccaattaag ccacctaaca aggtcaaaat catggattca
    24061 atcaaaaact gaattaaaat attggcacgt gttgcaccca aagccttacg aagaccaatc
    24121 tcacgagtgc gctctgtcac cgaaaccagc atgatgttca tgacaccagt tcctccaaca
    24181 aagagagaaa tccctgcgat ggaactaata atcgtcgtca taaaactaaa cgattgttga
    24241 atttctgcaa atacaacgga ctcatctgcc acctggtatt ctccctgttg taagcctgca
    24301 agctctgtca tttttcgtgc cagttctgga cccagagttg gggttaaact ggtatcattc
    24361 actcgaaaga caatactagc tatttcatct atattaaaat tcgcagcaag ggagatattg
    24421 gtagtaatag gcaagccacc aaacccatat atttttgacc ttttagcctc cggactagta
    24481 taaaccccaa tgacccggta actaaatcca ttgacttcta caaccttgtt aatagcctct
    24541 tgaggagatt caaataaact aatggacaat tcctcatcta gcaaaataac acttgcaaac
    24601 tctttgaaat cttgctctct cagactacga cctgcaataa tttcattctt aacagcgtcc
    24661 atgtaagttc tgtttccacc tgtcaaatta gtattctcaa cctttttatc ttgataggtc
    24721 aagatggcat tcgttgaatt ggttacatag taactatcca ctcccttcag tttagctgcc
    24781 tcttgaaccc aggattcttg cggttttggc ggttcaacag gaacttcctc ttcctttcca
    24841 gaaaccgtaa aagctgattg tttctgagta aaagacccat ctttactttt tttaggagag
    24901 aaaaagacgc taatattttt ctgagattta gtcatatctt tattgacttg acgagatagg
    24961 gaatcaccca aagccataat cacaacaact gatgaaacac cgataataat cccaatcata
    25021 gtaagcaaag aacgcatctt gtgagccatg atagatgaaa aggcaaattt cagattctgc
    25081 atcttagttt tcctcctttc ctaactgagc actgtcagac gaaatgaccc catcccgaat
    25141 gacaatctga cgtttggcat aggcagcaat ctcaggctca tgcgttacca tgataatggt
    25201 ttttccttct ttattcaaat caaccaataa ttgcataatt tggttacctg ttttggtatc
    25261 caaggctcct gtcggttcat ccgctaggat aatagaagga ttgtttacca aggcacgcgc
    25321 aatggctaca cgttgctttt gaccaccaga taattctgaa ggtaaatggt gactacgttc
    25381 tatcaattca accttgtcta aatattcctc agccaacttg cgacgttttg aagacgaaac
    25441 tcctgcgtaa atcaagggca attctacatt ttgcagagca ttgagcttcg atagaagaaa
    25501 gaactgctga aagacaaaac cgatttgttg gttacggacc ttagctagtt gtttttcacc
    25561 aagcccagcc acttcttgac cttcaagata atattctcca ctggttggtg tatccaacat
    25621 gccaatcgta ttcatcagag tggacttacc agacccagat ggtcccatga tggctacaaa
    25681 ttcaccctca ttcacttcta gattgatatt tttgagaacc tgcagttctt ggtcaccatt
    25741 acggtaactt ctgaagatat tttttagact aattagttgc ttcatcagcc ttcacctctt
    25801 ttccttcttc caaggaagat gttggattac tgatgacctt agcaccgttc gttaaaccag
    25861 aagtgatttc ttgattttct gcgtcagcat ttcccaatga aacctcaact tttttagcct
    25921 tttgttgttc atccacaatc cagacataat ttttactatc atccattact agactgctaa
    25981 caggaacaag aatagcctta gttttgcttt taacctcaat gttgacagaa aaaccttgtt
    26041 tcaaatcacc aacctcgcct gtcacatcaa tagtataagg gtatttagaa cctgtattat
    26101 tcccggctgc tggactagct gcttcaccat tgtttttagg atagtcagaa atatagctta
    26161 atttcccagt ccatttttta tcaggataca ctttagaagt aaagcttact tcttgaccta
    26221 cagaaaggtt ggctagattg tactcagaca attctccctt gacttgtaaa ttttcattgc
    26281 tgacaatatg aaccataact tgactcgccc ctgttggaga tttagaaaca ttgctattga
    26341 cttcgactac agttccctct agggtactga gaacagttgt tgcatccaat tgactttgag
    26401 ccttgcttaa ttgcgctgca gcatctgcac gcgcatcacg ggcatcaccc aattgagcat
    26461 caatagaagc aacagaattt ccagccactg gagttgggct ttgcaccgtt gcatcttctc
    26521 ctcctactgg cgctggtaac tgtggagcct gagctgaagc ggcttcattt cgtgcttgat
    26581 tgagttcatt gatatgacga tctgccttag ctactgctcg actagctgaa tcataggccg
    26641 cctgcgcttc tgaactactg tacttgacta aagcctgccc ttcgctgacc ttatcgccca
    26701 cagaaacaag gatttcatct aaatcaccct tactagcatc aaaataaaca tattgttcat
    26761 tttttgctgt tactgtccct gacaataaaa cagaggatgc cacgcttcct tccttggcaa
    26821 caacaagatg agtaggctca tcttttacag cagtctgaga aggttgtcta aaaagtaaaa
    26881 tccccccggc acccaataca actacactcg cagcaccgat tgctgcatac agttgccact
    26941 ttttagcttt accattcttt ttcttcataa tgaaactcct tttctttttt acaatacttt
    27001 gctattatac caaatttccc tccagcaaac aatgcagttc agatggaaat aatggcagtt
    27061 caggattaaa caatcgttcg gaattttact tttctattgt actagatata taatacacta
    27121 tcttgactta tttggcaagc ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca
    27181 aatcaaaaaa agaataaaat ataactatca aaaaagacac tctactattt aaaagattac
    27241 aaaggagttt tcaatgagag aatatgatat cattgctatc ggtggaggta gcggaggaat
    27301 cgctaccatg aaccgtgctg gtgaacatgg agccaaagca gccgttattg aggaaaagaa
    27361 attaggtgga acctgtgtca acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc
    27421 gcaaatcgct gagactttcc atcaatttgg agaagactac ggctttaaga ctactgatct
    27481 taactttaac tttgcaaccc tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc
    27541 ttcttatgat ggtagtttta aacgcaacgg tgtagacttg attgaaggtc atgctgaatt
    27601 tgtagattct catactgtaa gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat
    27661 tgctacaggt gcccatccaa gtattcctaa tattcctggt gctgagctag gtggctcttc
    27721 tgatgatgta tttgcctggg aagaacttcc agagtcaatt gccattctag gcgctggtta
    27781 tatcgccgtt gaattagctg gcgtactcca cacttttggt gtcaagacag atctctttgt
    27841 tcgccgcgat cgtcctttac gtggttttga ttcctacatc gttgaaggtt tggtcaagga
    27901 aatggaaaga acaaacttac cacttcacac tcacaaagtc cctgtcaagt tagaaaaaac
    27961 tactgacggc attaccattc atttcgaaga tggtactagt cacacagcta gccaagttat
    28021 ctgggctaca ggtcgccgtc caaacgttaa gggattgcaa cttgaaaaag ctggagtgac
    28081 tctgaacgaa cgtggcttta tccaagtgga tgaataccaa aatactgttg ttgagggaat
    28141 ctatgctcta ggtgatgtaa cgggcgagaa agaactgact ccagttgcaa tcaaggccgg
    28201 acgtacccta tctgaacgtc tctttaacgg aaaaactact gcaaaaatgg attactcaac
    28261 tattccaact gttgtctttt cacaccctgc tatcggaact gttggtttga cagaagagca
    28321 agctattaaa gaatacggtc aagaccaaat caaggtttat aaatcaagct ttgcatctat
    28381 gtactctgct tgcactcgca accgtcaaga atcccgtttc aaactcataa cagctggttc
    28441 agaagaaaaa gttgtcggac ttcatggaat tggctacggc gttgatgaaa tgattcaggg
    28501 atttgccgtt gctatcaaaa tgggagcaac caaggctgac tttgatgcaa ctgtggcaat
    28561 tcacccaact gcatctgaag aatttgtaac catgcgttaa tcgaaacaaa agaagctgat
    28621 ataaatatgt ctgcttcttt tttaatgatt ttcgaatcaa caaaaaaatt atccaacttg
    28681 actagtcacg aaaatcggct gttacagttt ttgttacctt gtttttaaaa aatggttgac
    28741 atcgactcct atatgagtat aatagttact atacattaga aaagaggtta actattttga
    28801 aaaaagctca cgtttatgct atccctgcta ttggggctgc tctcattgct gctttggcac
    28861 aaatcagtct tccaattgga cctgttccct tcactctgca aaactttgca attggcttga
    28921 ttgctactgt ctttagaccg agagaggcta tactttctgc tggactctat cttcttctag
    28981 gtgctatcgg tcttcctgtc tttgcaggag gtggagctgg ttttcaggct ttagttggcc
    29041 ctactgcagg ctatctttgg ttttatctcg tttactctgg acttacttcc tctctaacca
    29101 acagcaagag tggtgttgtt aagatttttc ttgcaaacct cttgggtgat gcccttgtct
    29161 ttgtcggcgg gattctcagc ttgcatttcc tagctggaat agcatttgaa aaagctcttg
    29221 ctgtgggggt tcttcctttt atcattccag accttggcaa acttctggct attagtttta
    29281 ttagccgtcc cctacttcaa cgccttaaaa atcaggctta ctttactaac taaaaaagga
    29341 tatcgagtta tcatgactca atatcctttt cttttatttt gaaaacttat actcaatgaa
    29401 aatcaaagag caaactagga agctagccgc aggctgctca aaacactgtt ttgaggttgt
    29461 ggatgaaact gacgaagtca gtaaccatac atacggcaag gcaaagctga cgcggtttga
    29521 agagattttc gaagagtatt agttgccttt aaaggcatcc accatcgttt gaaattcttc
    29581 atttgagaga gtaatccctt tgcccatttt agtatggtct ggactccaag cacgaatatc
    29641 aaactttgca ggggcaccat taaagctcac acggttaatt tccttggtcc aacctttttc
    29701 gttttcagaa agagtcaaca agtgctcttc gatttcaaat gtaaattctg ccattttctt
    29761 ctcctttttt agtttcatta gtttattcgt aaaatcttgt agattttagg aaaattttat
    29821 ataatattga tataaaagaa gggaggccaa tatgagacat aaattccagc aagttctaaa
    29881 taaaatacat gattttttaa atggatatga ccaacctgac cagactgaaa ccaactccct
    29941 tacagccact attgaagagg ctatccagaa acaaaccgct gttcacctta tcttgtctga
    30001 gacaagcttt acaggtgaca tcatcaaata tgatcagcaa ggccagcaaa ttatcgtgaa
    30061 aaatttttcc aaaaatgtga gccggattat ccgtataagc gatattcaac gcctgcgatt
    30121 tgtcccctca actgtccaaa cagcccaaaa aaatagattt aagaaagagt gagatgtagt
    30181 tgcttcatcc cactcttttt cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg
    30241 atctccataa ccacttcttt ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc
    30301 aatggtaatg taacctgcgc ccaataaacg atgttcaacc atagattgaa tcatactgat
    30361 agtcgcacgt tccaccttgg cttcttgtaa atccaaaact accttcttag tgacttgagc
    30421 aagattttga cgcaaatcat ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc
    30481 ttggtaaatc ttatctggat taaattcagc aatttcgcca ttacgtttga ttacttgcat
    30541 aggtttctcc tttattcttt gttttctttg atttctgcca gcattttttc ttcttctact
    30601 gtcagttgat aatgttcaag taaatctggt ctgcgctcgt aggttttctt taaactctcg
    30661 tacaatcgcc actgacgaat cttttcatgg tggccactca tcaatacatc tggcacgacc
    30721 atgcctcgat aatcataggg acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa
    30781 ctatcatctt ggtggctaga ctccttgcca atcacttctg gaatcaggcg aactgtagca
    30841 tcaatcatgg tcatagctgc caattctcca ccagtgagga catagtcgcc tagggaaatc
    30901 tcatctgtta ccaaggtctt aatgcgctca tcataaccct catagtgccc acagataaag
    30961 attagctctt cctcttgagc caaatcttca gcataagcct gatcaaactg ctttccagca
    31021 ggatcgagga gaataacgcg cggatttttc ttttcaatag catcaaagga attgaaaata
    31081 ggttgtgctc tgagcaacat gccctgaccg cctccgtagg gctcatcatc tacatgacgg
    31141 gccttttcag cattttctcg aaaattatga tactggatat ccaagagccc tttttctcga
    31201 gcctttccaa cgattgagtg ctccagtgga gaaaacatct ctggaaagag ggttaaaata
    31261 tcaatcttca tcgtctaacc cttctaagat ttccacatcg acccgtttat ttggaatatc
    31321 aacattgaga accactggtg ggatataagg taaaagcaaa tcacgtttgc cttttcgttt
    31381 gaccacccag acatcattag cacctggttg caggatttcc ttgatggttc caaccaagct
    31441 atcaccctca tagacttcca aaccgataat ctcgtgatag taaaattcac catcgtctag
    31501 gtcattcaaa tcttcctcag cgaccttgag actgtatccc ttgtactttt cgatagtatt
    31561 gatatggtac atatctttga atttaataat gtcaaagttc ttctgtttac ggtggctagc
    31621 gatggtcact gtttggacaa actgatcttt ttcatcaaac aaagccagct cagctccttt
    31681 tttaaaccgt tcttctgcaa aatccgtcac agacaagact cgcatctcac cctgtaatcc
    31741 ctgcgtatta acgattttcc caacattaaa gtagttcatc ttgtctcctg taatctcctt
    31801 ttttccatct tattctgaca attctcgaat aatagccgca attttttccg attctgacca
    31861 ttgtaaataa tggtgattcc ttcctaaaat gagtttagta ttggaagtcc aatattctga
    31921 ttctctgtac tctttttctc tataagtctg acaaaaaata aatacaggga catgagattc
    31981 tatcgacaaa ttctcaaaat cttcctcagt aatctctcca gatatctgaa attctggatc
    32041 ttgattttcc aactctaagc ctttttcttg cattaattcc cagatttttt tattcgtttc
    32101 aggactaaat gttgcttgag ttaagttctt aaaataaagt tcaggaccac actcgtcaat
    32161 cagcctcatc tgctcttcca tttctggata aggattttct gaaaaatcag caaacatgac
    32221 ttttttagtt gtcggttcaa ttgctactaa agtctgacgc ttaattggtt tctcgagtaa
    32281 tttgcaagct aaaattccac tccaactatg tgcacaaagt atatattcag aaattcctaa
    32341 ttcttcaagt acttcataaa ccgcatctgc aagattatct agattttttc cagcttggtc
    32401 atgaatcgga ctcctacctg tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg
    32461 aggtttttca agtataagtg aaaaattttc ataacttggt agcaaacctg ctccgtttag
    32521 acaaactagc actttctttt gcttttgata agtaacagag aggctaccaa tttctgtaga
    32581 tacttcaaac ctcttcataa agaaatccac tcattctata taatgaatta ttaaaaatcc
    32641 ttatccttta ttttatcacg ttccaaagat tttctcaagt tggaggaagg ggacaacatc
    32701 tctactttcc cttcaagaat ccttccaaat catgtttatg ttggtaatta acggctgcgg
    32761 ttttgtcttt ctcaaagatg gttctagtta ggtcaatatg cttgatagca gcaatagcga
    32821 cggtgtagtg aatgatatca gccagttcta tggcaggttc ctcgttcgaa tcctatccct
    32881 tcttttcgac cagagcgcct attcaaaacc tcggctactt ctccgacttc ctccactaac
    32941 ttcataaaga gaccttcatc agtccgagac tgctgttaat gttcgagtaa gtagtcttgg
    33001 aattgcctaa acgttcaatc ttttatagta tattgaaact agaatagtac acctttactt
    33061 ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttgtcctgt tattatttca
    33121 ttttactata tcttctattc cacacaaaaa agcgagacat ccgtcccgcc cttcttattt
    33181 ttcgtcaata acgattctta cttttttgta ttcagttggg acagagtaga caatcgttct
    33241 tatcgcagaa atagtgcgac ccttacgacc gattacacga cccacatcgc tttgatcaag
    33301 attcaaatga tattccaaaa attctggtgt atcttcaatc ttgatagtta aggcatctgg
    33361 ttgtgaaatt aagggtttca caatcgcaat aatgagattt tcaatcgtat ccatctgtca
    33421 acctacttta aacttatttt gagaatttag aatcgtggaa ttttttcaat acgccttctt
    33481 ttgaaaggat gttacgtact gtgtctgaag gttgagctcc attagccaac catgcaagaa
    33541 cgcggtcttc tttcaaagtt acttggtttt cagcaacaag tgggttgtaa gttccaactg
    33601 tttcgatgaa acgtccgtca cgtggtgaac gtgaatctgc tacgttgata cggtagaaag
    33661 gttttttctt agaacccata cgagtcaaac ggattttaac tgccattttt aaagtctcat
    33721 ttctttaatt ttttatttcg gtgaaatagc tgagctattt agcacatgtt ctattatagc
    33781 agatttttgg catgtgtcaa gaaaaaaact tgacagacta taaatttctt aaagtattta
    33841 gaaatttgtt agaataggaa ataaatgttt gaaagatact atccgtgaat actattttag
    33901 aaaaatttta taaagaacac caagtcaaac ccttcatatc gcctgaacga gatttggata
    33961 cttggctcct aagtcccaag cccgttccca agcgaaatat gaacttatta gcagatgatt
    34021 cactagcagg agatatcatt ttactatgga gaatccagtt tggtactttt accactgaaa
    34081 catgatttta aaaactccca ttcgaatatg attcaaaatt cgcttagaat caatgttttc
    34141 ccgctttttc aaaaaataaa ttttcatcta atttaaataa ctttcaatta agtgtgaatt
    34201 ttgcttaaaa tcattaaaaa gcaccccatg gtgtgaacca tgaagtgttg taaatgctgt
    34261 gttgtagcta gttcttagcg tttagagaac tggctagctt tacgagcttt cttaagatct
    34321 ggtttccaaa atactttgag tacacttatg gtattgatgc ccctaaacat ctaaaaactc
    34381 tggtagaaaa agggtatgct cttgtcgaaa cttcttttga ctcacttgac catctaaata
    34441 ctaccatgaa aaagaatatc ctgaagaaga agggagttac tggactttct aaaatgaaat
    34501 cttgcgacct ggatcaagcc cttcatgagc atttttcaga agaagaatta gctggtcact
    34561 ttcatgtcct tctatggact tttttacaat ggcattgcta tcacacccaa tacctatcta
    34621 agcgcctggt tcgtaaactt tattgcagct cttcctctaa atttcctaat tgttgaacca
    34681 attgcccgtt ttatactaag ttcttttcag aaaccattta ctggggaaga agttgaagaa
    34741 gttgaagatt ttcaagatga tgatgaaatc ccaactatta tctaagccag ttctgtaaac
    34801 tactaatatt tgaaatccac ttccttttag ggtacaatgg tataaatgaa tttttgagag
    34861 gatcagaatg aaaaaactag caacccttct tttactgtct actgtagccc tagctgggtg
    34921 tagcaacgtc caacgcagtc tgcgtggtga tgattatgtt gattccagtc ttgctgctga
    34981 agaaagttcc aaagtagctg cccaatctgc caaggagtta aacgatgctt taacaaacga
    35041 aaacgccaat ttcccacaac tatctaagga agttgctgaa gatgaagccg aagtgattct
    35101 caacacaagc caaggtgata ttcgcattaa actcttccct aaactcgctc ctctagcggt
    35161 tgaaaatttc ctcactcatg ccaaagaagg ctactataac ggtattacct tccaccgtgt
    35221 catcgatggc tttatggtcc aaactggaga tccaaaaggg gacggtacag gtggtcagtc
    35281 catctggcat gacaaggata agactaaaga caaaggaact ggtttcaaga acgagattac
    35341 tccttatttg tataacatcc gcggtgctct tgctatggct aatactggtc aaccaaacac
    35401 caatggcagc cagttcttca tcaaccaaaa ctctacagat acctcttcta aactccctac
    35461 aagcaagtat ccacagaaaa ttatcgaagc ctacaaagaa ggtggaaacc ctagtctaga
    35521 tggcaaacac ccagtctttg gtcaagtgat tggcggtatg gatgttgtgg ataagattgc
    35581 taaggccgaa aaagatgaaa aagacaagcc aactactgct atcacaatcg acagcatcga
    35641 agtggtgaaa gactacgatt ttaaatctta aaaaccaaaa aaatacagta tccacattcg
    35701 gtactgtatt tcttttactc tcattcttaa gttaaattat taaaatccca tatttggtct
    35761 atccaacctt cataaaagtc tggatcgtgg cagaccataa ggatagatcc cctgtattct
    35821 ttgagagcgc gtttgagctc atcctttgca tccacatcca aatggttggt cggctcgtcc
    35881 agcactaaaa cgttgttttc acgattcatc aagagacaga aacgaacctt ggcttgctct
    35941 ccccctgata atacttgaat ctggctttca atatgtttgg ttgtcaaacc acaacgggca
    36001 agggctgcac ggacttctgc ttgattaagg gcaggaaagg cattccagac agcttcaaga
    36061 ggagtttggc gattaccgcc ttctacttcc tgctcaaaat aaccaagttc taaataatct
    36121 ccacgctcca cttccccagc gattggcgag ataatgccca agagactctt caagagagtt
    36181 gtttttccaa taccattagc accaataatc gcaacctttt gattgcgttc gaaggtaaga
    36241 tttaaaggct tagtaagagg acggtcgtaa ccaatttgca agttcttggc ttggaagata
    36301 aagcgccctg gtgtacgagc tggtttgaaa tcaaaggatg gttttggttt ctcactttgg
    36361 agttcgataa tatccatctt atccaatttc ttttgacgag acatagccat attacgagtt
    36421 gcaacacggg ctttattacg agccacaaag tccttgaggt ctgcaatctc tttctgctgg
    36481 cgttcgtagg ctgcctctag ctgagatttc ttcatagcat aaacttcttg gaactggtag
    36541 tagtcaccag agtaacgcgt cagctgttga ttttccacat gatagacaat attgataacg
    36601 tcattgagga atggaatatc gtgcgaaatg agaacaaagg cattctcata gttttggaga
    36661 tagcgcttga gccaatcaat atgctcagca tccaagtagt tggtcggctc gtccaacagc
    36721 aaaatatcag gcttttcaag gagaagtttt gccaaaagca ccttggttct ttgcccacct
    36781 gacaaagaag ttacatccgt atccatgcca aagtccataa taccaagagc acgcgctact
    36841 tcgtcaatct tagcatccaa ggtatagaaa tcacgactct ccagacggtc ttgaagttct
    36901 cccacttctt ccatgagagc atcaacatcc gcaccgtctt cagccatttc catatagagg
    36961 tcattgatac gagcttcagc tttgaaaagc tcatcaaaag ccgtacggag aacatcacgc
    37021 accgactgtc tttcagcaag gacagagtgc tgatccaagt aaccagccgt cacatatttg
    37081 gaccactcaa cctttccttc atctggcagc attttaccag tcacgatact cataaaggtt
    37141 gattttcctt caccattggc accgaccagg ccgatatgtt ctcccttgag gagacggaag
    37201 gacacatctt caaaaattgc acggtcacca aaaccgtgac tcagattttt aacttctaaa
    37261 atactcattt taattcctta tcttgttttt atgtaatcgt ttataaagga gccaagacag
    37321 atagccaccc aaagtgttgg tccacaaatc atcaatctca aagacgcgat tgaaatcaaa
    37381 gaaaaagtcc aagattaatt gcgtacactc gattccaaga ctcacaagaa aactaaaaag
    37441 aaggaccttt tttgttttcc gcaaatttgg aaatagataa aggagttgga aaatcagagg
    37501 aaaaaacaag aagacattga ggatattttg taaaaaaatc caacataatt gtccaatgtc
    37561 actcacttcg cccagtttcc agagagaatt gaaaggagtc aaaagaaaaa ccaggcgtcc
    37621 aagatgctga atatctggag ttcccactcc cacggtagat tgttcttgag gagtaaagca
    37681 aaaatagaca atgcaaatgc tatagaaaat gactccccag accaaaatat gattataagt
    37741 cttcttcatc attaaggatt taccgctgcg actaccttct ggcggtcacg tttcattgtg
    37801 ttaaagcgca attgtccaca agctgcgtca atatctgtac catgctcttg acgaaccaca
    37861 cagttgcccc cttttttctt aagcgtatca tagaaagcca acacgcgctc tttgggacta
    37921 cggctatatt ggtcatgctc actaactggg ttataaggaa tcaagtttac ataagacaat
    37981 ttcttgatgt tcttgagcaa ttcagccaat tccaaggctt gttctacacc gtcattgact
    38041 tcattaagca tgatatattc aaaggttaca cgacggtttg ttgtctcaat gtagtattca
    38101 atagcagcaa agagtttttc aatcggaaag gcacggttaa tcttcatgat acttgaacga
    38161 agttcattgt tgggtgcgtg aagagacacg gcaagattga cctgaacccc ttcatcagca
    38221 aagtcacgaa ttttatgagc caaacctgag gttgaaaccg tgatgtgacg agcaccgata
    38281 gccattcctt tatcatcatt gatagtacga aagaaattca agacattgtt gtaattatca
    38341 aagggctcac cgattcccat gacaacgata tggttgacgc gttcatcctg accacgctca
    38401 tcaaagtatt tctgaaccag catgatttgc gctacgattt caccgttatt gaggtcacgc
    38461 tgcttcttaa tcaaaccaga ggcacagaag gtacaaccga tattacagcc gacctgagtg
    38521 gtcacacaga cagataaacc atagtgttga cacatgagta caatctcaat taacataccg
    38581 tcaggcaatt caaagagata tttgactgta ccatcagcag actcttgcac aatacgttgt
    38641 ttcaagggat tgaccacaaa ctggtcattg agcttagcaa tcaaatcctt ggaaaggttg
    38701 gtcatttctt caaatgactg cacacgttta cggtagagcc attcccagat ttgatctgca
    38761 cggaatttct tttctccctg ctccaatacc cattcctgca tggtttgatg tgccaaacta
    38821 tgaattgagg gtttcatttc ttctccttat tctctactca cttctgacga atgacaaaat
    38881 gacgttgttc cttgtcctct ttctgagaat gctggtcttt ctgacgacgt ctatttttct
    38941 tatctgcatt cgactttcgt ttagtttgag tcggtttctt tccttttcta gaaggtgttt
    39001 cttcttccgt cttacgcatt ttcttgtcaa atgatgctcg cttaggggct tcattttcta
    39061 agacaaaata ggcacaacca taactacaat actctaaaag gtagtcttgt aaacgactga
    39121 ttttttcaag tttttcttct gttcggtcat ccttgtaaaa acctcgtagg cgaagctgtt
    39181 cgttgctcca gtcccccacg atataatcaa acttggttaa tacttctgaa aaacgctgat
    39241 taaaagtcgt cacatcaaag gcatccttga tattttcaac caaggaaaaa gctatccctt
    39301 ccgtttcgac cttgtccccg tgtaaatgga actccggacc aggaaacttg ttatagttgt
    39361 ataattcagg tgcaatttct tttcgcatag atatcctttt tccacgatta cttaatactt
    39421 tattctacca taatttctag cagttagcac gtttctcata aaaatgaaaa aagtctgacg
    39481 attttgtcag accagaatct tataacctaa aaaagagaag aacaattctt ccctccaact
    39541 atcattattt agcagctgcg tacaattcat ctactttatt ccagttgatt actgaaaaga
    39601 aagctttgat atagtcagga cgcacgttgc ggtatttcac gtagtaagca tgttcccaaa
    39661 cgtccaagcc caagattggt tttttacctt ctgagattgg tgtgtcttgg tttgctgttg
    39721 aagtcacttc aagtttccct tctttgttga caaccaacca tgcccaacct gaaccaaaac
    39781 gagttgttgc tgctgcagtg aaggctgctt ggaattcttc aaatgaacca aatgttgcat
    39841 cgattgctgc tgccagttct gctgaaggag ctgttttctc gggagtcatc aattcccaga
    39901 aaagagcgtg gttcaagtgt ccgccaccat tgttgataag tgcttgacgg atatcagctg
    39961 ggatagattc tacatcagca agcaaggctt caaggtcttc accgatttca gggtgttttt
    40021 ctaaagctgc attggcattg ttgacataag tttgatggtg tttgtcatgg tgcaaatgca
    40081 ttgtttccgc atcgatgtat ggttccaaag cgtcgtatgc atatggaagt tctggtaaga
    40141 taatagccat ctgtaatacc tctttttctt tctatatgaa aatgataacg caaacattca
    40201 cttttttcaa gttttttgct tatagataag gaaatcactg acatactttc taataaaata
    40261 agcaaatcag caagaaaccc acgacaagat aatcctgacg cgggttgtag tttcaacaaa
    40321 tgtcaattga cctgactagc aatctgtaag agtgcctttt caaaaaggaa acctttttca
    40381 taaagacctg tcttaatctg atagtctgtc tcaatcaaat aggaaatagc ttgcttcaga
    40441 aagctcaaag aaagtcctct cgaatctctt aatgcaaact tgatttgata aggatttggg
    40501 ttacgtccca gataactacc taaactactt gcaatctgcg attctgtttg gccagactct
    40561 gccaaaatct tcacctgagt aaaagtccga aattgtccca gcatgactgc aatcagtttg
    40621 atttcatctt ccccttgcaa ggtcaagtct ctcaccaaat cgcgcgcctg atccatcttt
    40681 ttagtcagaa taaactgagt taaatcaaaa atattgtcct gcaaggtctt gggaattgcg
    40741 ttaacaatat cctcttcctc gataacagaa tccgccttat aggactgtaa aaagagaaga
    40801 tttttctgga tttcgctaaa ttgaaacccc gacttgatga ggagattttc aaaagaatga
    40861 ttggtaaact gcagaccttg tttctgactc cacttttgga aatactggcg caattcttgt
    40921 tcttttactt ctactgcatc gaagaccttg gcatcacgct taagtaattt gactaaccgt
    40981 cttttgctat ccagctttcc ttctgcaaag attatcaact tggttgttgg agaaggattg
    41041 tcaaggtatt cctcaaatga cttaagctca tcatctgtca aaaagcgttt cttagcagtc
    41101 gtgatatcca taaaataatc taatatcacg attttctcat ccgcaaagaa aggaaggctg
    41161 accaactcca gttccacatc cttgtaaact acttctttca tatcaaagta ggcaaagttg
    41221 aggtcagcag aatcataccc aatctgtttc aacacttgac tcttcatcac ttcaaactga
    41281 ccctgatctg tccctgtaaa taggctcagg ctcggtaaat ttgataaagt caacttctga
    41341 ctttcttcaa tggctagcat cgtctctcct ttcttcagat ttttcgattt aatttagtca
    41401 atatagcgca atttcccacg gaaatcttct aagctctcgt agcctttttc caccatgatt
    41461 gctttcagtt cattggtaat gcggtcaaaa gcactgacgc cttctttgtg aagggtcgtt
    41521 cccacctgca ccatacttgc tccacagagg atgtgttcaa aggcatctcg accagtcaga
    41581 acgccacctg ttccgataat ttggatttga ggatttaaac gttgataaaa ggcgtgaaca
    41641 ttggctagag cagtcggttt gatgtattct ccaccaattc caccaaaacc attcttaggc
    41701 cgaataacga cagattcgtc ttctatatag aggccgtttc cgatagagtt aacgcagttg
    41761 acaaacttga gcggatattt gttgaaaata gctgccgctt gatcaaagtg aacaatatca
    41821 aaataaggtg gcaatttaat tccaagaggt ttggtgaagt aagcaaacac ttctgccaaa
    41881 atccggtctg ttgtctcaaa atcataggca atctgaggtt tacctggaac atttggacag
    41941 gaaagattta gctcagtcag accacgaaaa tcactctctt ggactttttt caaaatagta
    42001 tgggtttcct ctggagacat gccgaccaga gataagaaga aagttcggtt cgactctttt
    42061 tcctgcaaat ctaaaagata atccaaataa tagtctaagc cattatttgg caagcccata
    42121 gagttgatgg aaccaagtgg aacatcttgg tagcgtggct caggattccc ctgacggaag
    42181 tccaaggtcg ctgtcttagt aacaaaggtt cctgccgctg agtttttgac ctcttctaac
    42241 tcctctatcg tcatacaagc cacacctgct gcattcatca agcaattgtc aaactcaaaa
    42301 ccagcaattt gtgttttcgt tgataccatg attctaatcc tccagatttc ttttattgct
    42361 aatattatac cataatttta attctaggtt tactagattc tgtggttcta tctatttatt
    42421 cggaaaagaa agtctagtac agaagtcatg ctatggaaac agctagtgta ttagaagttt
    42481 gaacaaggct tgggtaacag acttttgaat gaagtccaag caacaaggag aaatctcaac
    42541 catgagtcca ttccatgact ctgttgctct agaaaacctt gcaatagtca agtgataacg
    42601 aataaaactt tggattgaaa tatccccaag attatctatt acgaggagaa atcttaacct
    42661 ttataatttt taaagaaata tagtaaaatg aaacaagaac aggagaaatc gatcaggaca
    42721 gtcaaattga ttgctaacaa tgttttagaa gttgaggtgt actattctag tttcaatcta
    42781 ctatacatgt aaatctctac tttcgcaaaa tggattttca gaacagtatc ccagtatagt
    42841 taaaaactat aaaaaagaga ggacgttccc ctcttaaaat cttattttac tgcttctttc
    42901 aaagcatcta ccttatccaa acgttcccat ggaagatcaa tatctgtacg tcccatgtga
    42961 ccgtaagccg atgtttgacg gtaaattgga cgcttgaggt ccagcatttg gataatccct
    43021 gcagggcgaa ggtcaaagat ttgacgagcc gctttttcaa gttgactttc agctactgtt
    43081 cctgtaccga aagtatcgat acgaacagaa acaggttgcg caacaccgat agcataggcc
    43141 aactgcactt ctgccttctt agcaaggcct gctgcaacga tattcttggc aatatagcga
    43201 gccgcataag aggctgaacg atccacctta gtcgcatctt taccagagaa ggcaccacca
    43261 ccatgacgag agtagccacc ataagtatct acaataatct tacgaccagt caaacctgag
    43321 tccccttgag gaccaccgat tacaaaacga cctgtcggat tgataaagaa ttttgtctta
    43381 tcatcaagat aagaagatgg aataacttct ttgatgacct tgtcaatcac atcttgatgg
    43441 atttgttcat tagtggcctc tggatcatgc tgagtagaaa taacgactgt atctacacgt
    43501 accggacggt cattttcatc gtactcaact gtaacttgtg attttgcatc tggacggaga
    43561 tagctaattt ctccagactt acgaagttct gccagacgac gaatcaattt atgactgagt
    43621 gcaattggca atggcataag ctcttctgtt tcatctactg caaatccaaa catgagccct
    43681 tggtcacctg ctccaatcaa gtccagtgga tcttgatcag catttccacg aacctccaag
    43741 gcttcgttaa caccttgagc gatgtcagga gattgttcca ccaaagatgg gtgtactccc
    43801 accgtctcag cagaaaatcc atattctgta ttggtataac caatctctgc aatggtatca
    43861 cgaaccacac ggttaatatc cacataggca tttgtagaaa tttcaccaaa aacgtggaca
    43921 gaaccagtat atacagctgt ttcagcagca acgtgcgcct ctggatcctt tgctaaaata
    43981 gcatccaaaa tcgcatctga aatttggtct gcaatcttat ccggatgccc ctcagataca
    44041 gattcagacg tgaataattt acgctctgac ataaaaatgt ccccccttaa aaaatattgt
    44101 tatagagtta caaagtactg ataggaaaac tcttcgtaat aaatacctac catcttatcg
    44161 ggactatata actttatcat tataccattt ttaatcgcaa tttgcagtct ttaatgtagt
    44221 atttcggttt agatagttcg ttctcataaa gcaaaaagtt ggagctcagt actccaacaa
    44281 tttctattaa aatgtttgac gtttagcttt acgctctgca cgaccgcgag cgcgattttc
    44341 agcacgcttg gttttacggc gcttttcatc aaccgcccat tgaattttct tcttataacc
    44401 cggtttgact tttttctttt tctttttaac caaaccaatc atttcgatat caagtttatc
    44461 ttgttttttc tcacggttgg cacgacgatc acggtcatag gtatcttgaa attccccgtc
    44521 tttgaccatc ttaggactaa acttgattcc caatttctcc aactcacgga tatccgagtc
    44581 atcacttggc tgataaaggg taatagctgt acctggtagg ccatttcgtc cagtacgacc
    44641 aacacggtga acaaaaaaag ataagtcttg cggaatggca tcattgatga catggctgac
    44701 accttcaatg tcaatcccac gtgctgccaa atctgttgcg acaatatact caaaatccag
    44761 attttgcacc tgattcatga ttcgcttgcg ttcacgaggg gcaatatcgc catggatttt
    44821 tgcaaccttc aagccttgag cagtcagata tgaatgcaat tcatcagcac gcgttttagt
    44881 gttaacaaaa atcattgcca aatacggctg catcaactga gtcaactggt aaatttgagc
    44941 attcttatca tgtcccttgg tcgaaatcaa ccaattatca atggtgtcag aaataaccgt
    45001 tttggtctta attttctcca taacaggatt ggataagtat tttttcaaga atggttgcag
    45061 tttttgtggg acagtcgctg agaagaccat gaattgcaag tcttttggaa gactgccagc
    45121 aatcttatca acagtttcca agaatcccat atccaaggtc atatccgctt catcaacaac
    45181 aaatgtcttg gctttatgaa tagctaaatc accagattta accaagtcgt agatacggcc
    45241 tggtgttcca ataacaatat gaggctgatt gcttgccaat ttctcaatct ggcgagcctt
    45301 atccgtacca cccacataat taaccacacg aacttcgaca tctgagtgag ctgaaatctg
    45361 acgcgctact tggtaaattt gagtagccaa ctcacgactc ggtgcagtaa tcactgcttg
    45421 tacactatcg ctagcttcat ctaattgctg gaaaatcggt aacaagaaag tatgagtctt
    45481 acctgaacct gtttttgatt ctcctactag gtcacgacct gccaaaacaa taggaatcaa
    45541 cttgtcttgc acctctgttg gagttgtaaa ttttaactcc tccaaggctt ctctaatata
    45601 gtttttaaat tgaaatttcg taaatgacat aacatcctcg attctatcta tcttatcaat
    45661 tataccatat tttattccat tacagtagtc tcacttattt aggctatttc cagtagcttc
    45721 tctagtaaga aaaggctgga attttatagt tccaacctct tttcagttat tatttccagt
    45781 ttaacatagc attcaagcca tagtgatcac tcacttgtgg actcttgtta ccatcaaata
    45841 cgacatgtaa attttccacc gctaactctt tggtagtaaa gacataatcg attcgaaggg
    45901 gttcagtgtt ccctttccag ccatcaattt caggcggaac agtatagcta ccacttttct
    45961 cttgagcaac ttcaaatgcg tcttgtaagc ctaatggact agctaaaata gcttggtaac
    46021 cttcctgacc tgctgggttg ttaaaatctc cagctagtaa aagtggcttg ttcaattttt
    46081 tcaagacagc ctcaaatcgt gcccattctt cttgaaaacc tttatcccac caagagagat
    46141 gaacactggc aactgctagc tccttgccat cgactacagt ttcagctagg gcaacacggc
    46201 gagtatgata gtctgttgga tcatccacat ctgaaaccaa aatttctctg gcttcaatag
    46261 gtgttttaga caagatagcc acaccttcgt ggtagcggtc atagccgata tggttatagg
    46321 cccaggtcca gtagtaattt ttcccttgct cagataactt ttcaaccaag agtctaacat
    46381 agtgatcttg gtgaataggc tcagctgctg gcaaagcttg ataaaggtca ttaacctcca
    46441 cctctgacga ggtcatctcc tgattaattt cttggaaaca aatcaaatca tagtcctttt
    46501 caagaatatc ttcaagcaaa atctggaatt tttcctctgc ttctttctcc atccaactat
    46561 gagtattgag tgttaaaaat ttcattcttt tctcccaaaa taagaggttg gaatacagct
    46621 tccaacctca agtatattac aattctactt tagcaactgc tgttttagct gcaagagaac
    46681 ctgttttttc taatttaact gatttaattg catcaccatt tgtgaagaca actactgttg
    46741 aagtttcacg tcctgctgca cggatagcat tcaagtcagc tgtaacaagg agatctcctg
    46801 ctgcaacttt ttgtccttca gcaacatgaa ctgtaaatgg tttaccttca agacttactg
    46861 tgtccaaacc aatgtgaacc aatacttcaa gacctgcttc cgtcacaata ccaaaagcat
    46921 gttttgttgg gaagatgctt gatacagtac ctgaaactgg agatacaatg tttccatttg
    46981 caggttctac tgcaaatcca tcacccatca ttttttgagc aaatactgga tcctttactt
    47041 gttccaaagc aacaacttga ccgtctgcta ctgagtaaac ttcctcagta agatctttga
    47101 agtgaacagt gttttgttgt acttcagtca tttggcttgg aagagtttca ggaatgattt
    47161 cacctgaatc aaggatatct tggatatcag atttcaaaat gtcagctttt ggaccgtaga
    47221 tagcttgaac cccttgtcct ttcatcacaa gacccatagc tccttctgct ttccattgct
    47281 ctgcatttcc tactttatct gcatctttaa cagttacacg aagacgagtc atacatgcat
    47341 caacatcaac gatgtttaca cgtccaccaa gaaggttgat aatgtttaca gcttgagagc
    47401 ctgctgcaac tttcacttcg ctgctggttt cttctgaacc ttcagcagtt tcgtagtttc
    47461 cgttgcgccc tggagttgcg tagttgaatt tttgaatcat gaagtttgcg ataaagtaca
    47521 tgattacagc aaagagaaca gttacccaaa cgaagttaac gatatccata ccaataccag
    47581 cactgattgc aataggtgta cgagtcaaga actcgattga accgaatgag tgcatacgta
    47641 ggtttacgac gtcagccata gcgaaggcag caccttgaac aagtgagtaa acaagataca
    47701 taggtgttgc gatgaacatg aacatgtatt cgattggttc agtaacccct gtcaagaatg
    47761 ttgcaagagc tgttgcaatc atcatacctt tgtatttatg tttcttgtca gcatcaacat
    47821 tacggtagat agcaacaatc acacccatca agataccgaa tgaaccgatc atttgtccaa
    47881 ctttgaaacg agctggatgt actgtatcta acaagtgttg gtattgacta gcatcagtac
    47941 ctttaaggtt tacaaggtct gttacccatg caagccatag tgggtcttga ccgaatactt
    48001 gagtaccttt agctgcacca gttaaaatgt cataagtacc accaagagct gtgtagttca
    48061 ttgggatagt caacatgtgg tgaagaccaa atggcaagag caaacgttcc aaagtaccat
    48121 acaagaatgg tgcaagaatt ggagcagttt cttgtgagtt ggcaatccag ataccgaaat
    48181 tattgatacc tgtttgaact actggccaga aagcagcaag tagaattgca gcgattgctg
    48241 aacgaagaat aactacaaat ggtacgaaac gtttcccgtt gaagaatgaa agtgcatcag
    48301 gaagtttacg gaagttgtag tatttgttgt aagcagttgc ccctacaaaa cctgagataa
    48361 tccctacgaa tacccccatg ttcaaggctg gagcttcaag aacactgata aagtaagcag
    48421 caactttgat tgaaccacca aagaaagtag ttaccatagc atctggattt ttcaacatat
    48481 cgcctgatac accaaagatt gtaccagtga tacggttaat caagatgaag gcaagaccag
    48541 cggcgaaagc accaccagca cgttctttag cccagcttcc tccaatggct agggcaaaca
    48601 aaatgtgaag gttaccgata accccccaac cgatttgctc aagaattcca cctgtgatga
    48661 caagtggtgc aaaggttggg ttaatcatca cgatagactt accgattgaa atcatcaaac
    48721 cagcagccgg cataaccgcg ataactacca tcaaagcctt accgaatttt tgccaaaatt
    48781 cgaaagacaa gacatttttg aatgtatctt tcatcattca aatctccttt atttttattt
    48841 aggcaaacgt tttacgaaaa cgtttgcact ttctatgatt taattatacc actttaattt
    48901 tttttgtaaa ggcttttata aaaaaattac acttttttct aaaaaatttc tagtgcgcca
    48961 aatttcaagt tcaaattagc catcaagaag tcttctctgg gggacttctt tggaagctct
    49021 tttcttctgc gcatctcttt tcaaaaactc ttgtagcaaa aaaggagatt ttacaatctc
    49081 ctcataaaag cagctatttt acctaaatct tcaagaatcg gcgcatggat attcctgatc
    49141 ccaatgaacc aatgaaaacc ccaatcacaa atagtagggc aatcatcaac ggactaaata
    49201 aatctggact aatcatggat agattttgcc ctaccaacga tttgttgaca gattggtaaa
    49261 caatttgata aacaataaag accaaaacag atggtgcgat agctcccaat aaaccgataa
    49321 aggctccttc taacaagaac ggtccacgga tataactgtt tttagctccg accaagcgca
    49381 tgatttgaat ttcgcgactg cgggaaataa tggtaatacg aatggtattt gaaatcaaga
    49441 aaactgcgat aaaaattaac aaagcggcaa tccctagtcc ccaaacacgg ataaatgaag
    49501 ctaacttgaa gagtctttct gtattggcac cgccatcttg aacctcagag acaccttcaa
    49561 tttttttagc atcttcggct atagttttta catcatttgg agtgtttgcc tctacaatat
    49621 aggcatcata gagaggattg gcatctcctt caaagatttt ccagttatct cccattatct
    49681 cggttaattt ttcatattgt tcttctttac ttgaaaaggt aacactttta accgtagaca
    49741 tgttcttcaa agaatcatat accttgtggt agtcattatt tgtaacagtt tgaccttctt
    49801 tttcaattgt ctgactatta tcttccacat cctttcggat ataaactact acacggacat
    49861 tattttcaat atctgtagct agtttcgctg tattgaaaat aacagatgca aatattgcca
    49921 ccaaggtcaa agtaatcatg actgaactga cagcagctac tgtcatccaa ccatttcgtt
    49981 tcaaactttt taaggcttca aataaatggc gaaaaaatct actaatcatc gtatccatac
    50041 tctccttttg attcgtcacg aacgacacgg ccattttcaa tggcaatgac acggtggcgc
    50101 aaggtattta caatctggct attatgagtc gccatcaaaa tagttgttcc ttgtaggtta
    50161 atccgttcca agagattcat aatttcccat gaattatccg gatccagatt tcctgttggc
    50221 tcatcagcta tcaatacttt gggattattt acaattgcac gcgcaatcgc aatccgctgt
    50281 tgctccccac ctgagagttc atttgggaaa gaacgaacct tatgcttcaa tccaaccaag
    50341 tccaaaactt ccatcactcg tcttttgata ttacggcgat tttccccgat tacttccata
    50401 gcgtaagcaa tattttcata gacagttttc tttggtaaca atttataatc ctggaagaca
    50461 accccaacac tacgacgtag aagcgggata tctttctttt tgatcttaac cagattaaaa
    50521 ccagcaactg ataggcttcc tttatcgatt tttacttcac gatacagaga acgaataaaa
    50581 gttgacttcc ctgctcctga aggtcctacg atgtaagcaa attcccccgg ttgaacgcta
    50641 accgaaacac cgcgtagagc agtcgttccg ttgtcgtatt ttttaacgac atctctcatt
    50701 tcaataattg acatgtgagt tcctttctat cttagctaat tcgccacttg agataagcat
    50761 cgataaaacc atctaggtcc ccatccataa ccttatctac ctgagcaacc tcaaagctag
    50821 ttcggtgatc ttttaccata gtataaggcg tgaagacata agaacggatt tggcttcccc
    50881 aagtgatctc ctttttctca cctttgagag aatctacctc tgcagccttc ttctcttgct
    50941 ccatttgata gagcttagcc tgcaacatct tcatggcacg atctctattt ccatactggg
    51001 tacgatccac tgttgattgg acaacaattc cagttggaat gtgggttaaa cgtacacctg
    51061 ttgaaacctt attgacgttt tgtccaccgg caccacctga acggaaggta tccatcttga
    51121 tatcatcttc acggatttcc acttcaatag tatcatccaa ttctggcatc acttctacag
    51181 atgtgaaaga ggtatggcga cgtttggcag agtcaaatgg tgagattcgc actaagcggt
    51241 gaacacccat ttctgacttg aggagaccat aggcattagg cccttcaaat gataaagtta
    51301 ccgacttaat accagcctca tcacctgctt ggtaatccaa cacttccact ttaaagcctt
    51361 tagcattacc ataacgagta tacatacgaa gcaacatatc accccagtcc tgcgcctcag
    51421 taccaccaga acctggatgg atttccaaga tggcattgtt gtggtcataa ggttctgaca
    51481 agagtagagt catctcgtag ctggtcatta tcttatcaag ttcggctaac tgcgctacca
    51541 gttcatcatg cactgactcg tcttcagcca aaaaatccaa taaaatttcg acttcatcct
    51601 gcaactcttc catcttatgg aaggtattgt aagtgttttt taattcattt aattcttgcg
    51661 acgttttttg ggccgcaata ttatcgttcc aaaaatcagg ttctgtcatc ttgttttcca
    51721 agatggcaat ctcttcctct agcccttcga ggtcaaagag accccctgaa agaagctaat
    51781 ttttcacgat ttgcgtcaat tttctgacga attactgaaa tgtccataaa tactcctttt
    51841 ttacattatt tcattatagc atattttatc atttctttcc atctttttct ctaatcccct
    51901 tttcatgaaa aaagaagcct ttgggcttcc cttcttacaa gacttttgct gaagtgcgag
    51961 cgatttcttc cacttgaata ccatttgctt caaatttttc tttcaaggct ggtaaatcaa
    52021 ttgatccatc gatttgcact tcgataatca ccttaccatc cttacgcgga atattgactg
    52081 tatgggagat attcaaattt tcttctacaa tcaaagaaac aatttttcca agaacaccaa
    52141 cttcatcttc tgtaacaaag cgtacacgaa tcccttcttc gccataacct gcaatttcaa
    52201 gaaaggcttg gaaaacgtca cggtcagtaa taactccgta tacttgatgg ttatctacga
    52261 cagggagaat actaatctta tttttcaaca tcagataagt tgcatcttct agactagcat
    52321 agcctgagac agtgacaaca tcgcgaatca tgacatcttt tacttttgtc ttattcagaa
    52381 gataattcat ctcatagata gaaagacttg ttgctttaga tggacttgct tgtgcaatgg
    52441 ttccctcagt caccaaacca actaattgat cattttcgat aacaggcaga cggtgcaaac
    52501 cttgctctct catcaaatct gctgcatgag atactgttgt atctggacta atataaacta
    52561 ccttgcgggt cataaaatct ttaactgcca tgagacttct ccttttctat tcttatccct
    52621 attatacaat ctttttgtaa atctatcaaa cgcttacatt tctttttcga aattcagaaa
    52681 agtatgaata agctagcaaa aagagctctg aaatcgagct ctgtgaatga aggtaagaaa
    52741 tttttcattc gattttttca attattagaa attaagcttt caatgtagat gcagatttgt
    52801 ttgcaatctc aatctaccga ctaaaaaggt cccccggact atattgatga ttacttcgta
    52861 atctccatct gccgactaaa acaatccact ggattgtttt agccacctag atatgctttt
    52921 ctgacttctt ctgatgaagc gagttctttt cctgttcctg ataggacgat tttccctgtt
    52981 tccagtacat atcctcggtc agagattgca agtgctttat tggcattttg ttcaatcaag
    53041 aggaccgttg ttccttgctt ctgaatatct tgaatgatat caaaaatttc ttggataaag
    53101 attggggcaa gtcccattga tggttcatct aaaagaagaa gttttggtgt tgacatgagg
    53161 gcgcgtccca tggcaagcat ttgttgttcc ccccctgaaa gagtggctgc atcttggttc
    53221 ttccgttctt caagacgagg aaagcgtgag aaaaccttct tcaagttagc ttgattttct
    53281 tcacgatttt tctttaagaa agctcccatt tcaagatttt ccataacagt caagccagga
    53341 aagacgtggc gtccttctgg aacttgtgaa agaccacttg ccacgatttt ctgagctggc
    53401 attttttgga tttcttgacc taaaaattca atctttcctg aacttggtcg aaccaaacct
    53461 gacaaggtgc gaagaatagt tgtcttacct gcaccgttgg caccgataag ggaaacaact
    53521 tctccttcat taacttcaaa gcttacatca cgaactgctt ggatcatacc gtaatgcaca
    53581 gaaagatttt caacttttaa catagacatt aggcttcacc tcctagataa gcttcgataa
    53641 cgcgtttatt ggtcttaatt tcgtctggag ttccttgagc gattaaacgg ccatattcaa
    53701 gtacgtagat acgttctgtt acttccatga ccagattcat atcgtgttca atcaacatga
    53761 ttgtaatctt aaactcatct ttgatacgac gaattaactc agtcaattcg gctgtttcct
    53821 gtgggttcat acctgctgct ggttcatcta agaagagaat tttaggttcc gtagcaaggg
    53881 cacgaacaat ttccaaacga cgttgttgtc cgtaggaaag atttttagca agagtctctg
    53941 catcaccatc taaatcaaag attttcaaca attccaaagc tttagccttt aattcttttt
    54001 cactcttgta aaaagctggt aagcgtaaga aactagtaaa aacatgctgt ttgtgatggt
    54061 ttccaaaagc aatcaaaaca ttgtctaaaa ctgttaaatc tttaaaaaga cggatatttt
    54121 ggaaagtacg tccaagtccc aaagaggcaa tcttataagg tgatttccca ttcaaaaggt
    54181 gaccatctag ggttactgtt ccctcgcttg gttcataaac accggtcaaa aggttgaaaa
    54241 gggtggtttt cccagctccg tttggaccga ttaatccaac cagttcccct tcgttcaatt
    54301 caagagtcac atctccaaca gctgttagac caccaaaatg tttggttaac tgttttactt
    54361 caagtaatgc cattagtttt gttcctcctt cttagatttt ttaaagaaac gtgataggct
    54421 cagttcccac gttccaagga gtccacctgg tctgaaaatc attaccaata ccaaggccaa
    54481 agcgtaaata atcatacgca cactagcaac atcttggaga agcatattca aaattcccag
    54541 aacaatagcc gaaacaatcg cacctgtaat ggaaccgagt ccaccaaata caacaataat
    54601 caaaacgttg attgagttga tgaaggtgta atctttcggt acaacagacc cgataaatcc
    54661 tgcctgaagt gacccagcaa tacttgcagt aatggcacca aagacaaaag cgatgatttt
    54721 aattttagtc gtattaaccc caactgactc agcagcgatt tcatcttcac gaacagagag
    54781 ggttgaacgg ccaattgggc tacgcaagaa gttcaaggtt gcaatggttg taatcacgac
    54841 aaagaagtaa accatttgcc aagttgtaaa gttaggaatc cctaagatac ctgccgcacc
    54901 atttgtaaga cttccaccat tgatgataaa gatacggata atttcagaaa cacccagagt
    54961 tgctaccgca agatagtccc ccttcaagcg caaggttgga ataccgacaa gtaaggcaac
    55021 tgctcctgaa agcaaagccc ctacaagcat agctccaaag aaggcaccgt aggttggtga
    55081 tttagaacca ataatagctg ctgcataggc accaatcgcc atgaaaccag catgaccaag
    55141 tgaaaattgt cctgaaaaac caacgattaa gttgagacca acagccaaaa taatattaat
    55201 tccaatttgt tgtaaaatct gtacatagaa tagattaagt actccgactg aaaccagtac
    55261 actaatcaag ctatagccag ctaacaaaag gagtaaccat agaatattaa cttttaaatt
    55321 ttccttcatc gtttacacct tctctttcac attcttacca aggataccag ctgggcggac
    55381 aatcaagatc aacaacaaga ttccataaac aatggcatca cggaaatctg acatcccaaa
    55441 ggctgtcgca aaggtttcca atagaccaat cacaaagcca ccaagagccg caccaggaat
    55501 aattccgata ccaccaagta ctgcggcaac gaaagattta agacctggag taacccccat
    55561 caaaggctca agagagttat aataaagagc aatcagaaca ccagccgcac ccgcaagagc
    55621 agaacccaaa gcgaaggtaa agctaatcgt acggtttaca ttgatcccca tcaattgtgc
    55681 cgcgtcgcta tctactgata ctgcacgcat ggctttcccc atcttagtct tttggacaat
    55741 gacttgtaac aaaatcatca aaatcaagga aatggccaaa atcattaact gcacatttgt
    55801 taagctaatt ggtcccaaat catatcgaac tgtttgaatc gcttgaggga aggcacgggt
    55861 attggcacca accagataga ccattccata ctccaatagg aaagaaaccc caatagccgt
    55921 aatcaaaaca gcaatacgag tagagtggcg caaaggtcgg taagcaagaa actcaatcac
    55981 gacaccaaga atagctgtcg ctagcatagc tacaataagc gctacaaaga aattcatttg
    56041 gaaagaattg atcaagaaat aaccgataaa ggctcccatc atataaatat caccatgggc
    56101 gaagttgatg agcttgataa ttccgtaaac catggtatat cctagggcta acagcgcgta
    56161 aacactacct agaatcaaac catttacgag ttgttggagc ataagattca ctctttctat
    56221 ttataattcc gagggttttc cctcactttt tgataggttc ttatactcaa tgaaaatcaa
    56281 agagcaaact aggaaactag ccgcaggttg ctcaaagcac tgctttgagg ttgtagataa
    56341 gactgacgaa gtcagtcaca tatataatcc aaggcgacgt tgacgcagtt tgaagagatt
    56401 ttcgaagagt attaaatatc gaaacaggga gtgagtcaaa ggctcattcc ctatttcaac
    56461 atttttctat tatggtttta caacttctgc tgcttcaact ttaccattgt tcatggtcat
    56521 catgtaagca gttttgactg tgttgtggtc tgcatcgaag cttgtttgac cagttacacc
    56581 ttcaaaatct tttgttttag caaggttatc cttgatttca cctgaatttt tagcaccttt
    56641 tgctgcgttt gctacaaggt gaactgaatc ataagccaag gctgcaaatg ttgaaggctc
    56701 ttcattgtac ttagcacggt aagcgtcaag gaaggcttta gctttagctg aaacttctac
    56761 agtagttgag aagcctgaga taaagtagat gtttgatgct ttttcagcag ttgcttgttg
    56821 tacaaactcc tcaccgttga atccatcacc accaacgatt ggtttgtcaa ttcccatgcc
    56881 acgcgcttgg tttacaattt taccagcctc attatagtaa ccaggaacaa cgatagcatc
    56941 aaagtctttc cctttcattt ttgtaagggc tgcttggaag tctgtgtcac ctgctacgaa
    57001 agtttcatct gcaacgattt cacccttgta tgactcgcgg aaagatttgg caatcccttt
    57061 agcatagtca ctggcattgt cagtgtaaag aacaactttc ttagcattta atttttcaga
    57121 aacatagttt gagataattt ttccttggaa gctatcttgg aaagttccaa taaagaggta
    57181 atcttgacct ttagtcaatc catcttgagt cgcacttggt gagatcaatg gaacacctgc
    57241 ttttgtagcg ttcgctaccg cagctgcagt cgcaccagat gtcgcaggtc ctacgactgc
    57301 tgatacttta gattgggtta caaggttagt tgtaactgaa gcagcctcag ctgtttcaga
    57361 cttattatct ttatcgatta cttcgatttg ttttccatcg ataccacctg cggcattgat
    57421 ttcatcaaca gccaattggg cacctttttg ttcagctgtt ccgtatgcag ctaaagaacc
    57481 tgattcttca aagttaaacc cgattttaat tgtcttttcc tctactgagt taccagcagt
    57541 gttgactgct ccagacttca cttctccaca ggctgcaaga agtgctacac ttgcaagcgc
    57601 cacaaacgat agggcaaatt ttttcttcat cttttttgtc tccttatttc ttaaatagtc
    57661 tgttaagaat ataccgaatt atcagaaaat tgtcaatgtt ttccttgaac tttttcgatg
    57721 ataacgtttt cctatcgata aagattgccc acaaagggtg tttccaactc ttggatatga
    57781 caaaccctaa cttttttaat aaatttttcc ttgctcaagc gtccgaccaa ttgctccact
    57841 tcttgagttg gaacatagag ttgtaagtaa cgatgtttct tggaatgata ggtaatatct
    57901 ccataatcct gcagtttttt ggcatcacga ttatagtaaa gatagataat caagccagag
    57961 cgattgactt tttcaaacat gataaatcct ctttctaaga aatctctccc tattatacca
    58021 aaaaaagcaa acccagtcga gtttgccttc tatcatcatt agttcaatga attgttggcc
    58081 ataatttcat caataaagcc atattcaagt gtttcctggg cgctcatcca gttatcacgt
    58141 tctgcatctg catggacttt ttccattgac tgacctgaat tttcagccaa gattttttcc
    58201 aaggtattac gagttttgag caagtgttct gcagcgatag ccatatcagt ttgttgggta
    58261 ccaccacctg taccgcccat tggttggtga atcatgtatt cagcatttgg aagcatgaaa
    58321 cgtttgcctt ttgctccact tgatgcgatg actgttccca tagatgcagc cattcccata
    58381 acaatggttt ggacatctgc cttgataaag ttcatggtat ctacgattgc caaaccagct
    58441 gaaacagaac cacctggtgt attgacataa aggtaaatat cttttgtact atcttgggca
    58501 tccaagaaaa gcaattgggc aataacagag ttagccatat tgtcttcaac cggacctgtc
    58561 agcataatga tgcggtcttt gagaagacgt gagtaaatat cgtaagaacg ttctccacgg
    58621 cttgtttgtt caataactac aggaatcatt catttctcct tttgagtttt aattttgttg
    58681 gtcaaatgac tgaagataag actattataa tatcttggtc aaaaaaggtc aaatttttgc
    58741 tctgctttca ttagacagaa acaaaaaccc aacctccttt cgtgactgga aatacttttc
    58801 caagtcattc ttcttttcga tcttattttg taccgaacaa gcggtctcca gcatctccaa
    58861 gacctggaac gatataaccg tgttcgttca aacgttcatc caaggctgct gtaaagattt
    58921 ctacatctgg atgagcttct tgaagggctt ttacaccctc tggagcagat acaaggcaga
    58981 caaatttgat atttgatgcg ccacgttttt taagagaatc aacagccaag attgctgagc
    59041 cacctgttgc caacattggg tctactacaa aaatttgacg ttggtcaatg tcctcaggta
    59101 atttcaccaa gtattcaact ggttgaagtg tttcttcatc acggtacata ccgatgtggc
    59161 caactttagc agctggaacc aagttcaaga gaccatcaac catcccgata cctgcacgca
    59221 agattgggac gatggccaat ttcttacctg ccaattgttt ttgaactgtt tttgtaattg
    59281 gtgtttcgat ttccacatct tctagtggaa gatcacgaag tacttcatac cccatcaaca
    59341 ttgcaatctc atctactagc tcacgaaaag cttttgtaga agtatctgta cgacgcaaga
    59401 ttgacaattt gtgttgaatc agtgggtgat taataacttc aatttttccc atttttggaa
    59461 ttccttcttt caatttattc ttcttattat accaaaaaac ggtttaaaaa tctttctaaa
    59521 ccatttattt ttgataattt ttacattaga tcagcctctt taagagctgt ctgtactgtc
    59581 tcaagtggta aatgggtcaa ttctgtccct ttttcttgat aaaggtattg ggcgtagtcg
    59641 tccattcggt actggttgat ataaaccaca cgcttgcagc cgacctgaag caattgtttt
    59701 gtacagttga gacaaggaaa atgggttaca taggctgtaa agcctttggg aacaccacgc
    59761 tcagcacctt gaaggatagc attgacctca gcgtgaaggg tgcgaacaca gtggccttca
    59821 atgaccaaac attcgtgatc aatacaatgc tcagtccctg acaccgaacc attgtaacca
    59881 gtggaaataa ccttattatc ttttaccaga atcgcgccca ctttagcacg tttacaagtg
    59941 gaacgattcg caattagtag ggcttgggct gcaaaatact catcccaggc cagtcttttt
    60001 tcagtcatct cttttctcct ttttctctat tttttaaaaa atggtaaacc taaatctgca
    60061 atcttttcag ctggtacctt catgccatcc ttgatccatt ttagaaggac agagacgatg
    60121 gctgagctcc agaaggaatg aagataagag ctgacacctt ttgatttccc atggtatttt
    60181 tctagaaatt cctgcatggc ttggacaaag attttttcca gatggtaatc caaggccaat
    60241 tgaattactc tagcttcctt tctggcctcc cggaaaaggt gaacccaaac caaataaagg
    60301 tctgtcttta aatcgtaatg atgcagctgt tccataatat tgtggacagt tcgtttaaag
    60361 acgctctcta aaatttcctc tttggagtca taattgcgat aaaaggccgc acgcgaaaca
    60421 cctgcacgtt tgaccaattc agaaatacta atcttggtca gttccttttt ttccaagagt
    60481 tgcaagaggg ctgtttcaat ggcttctctg gttaataaat tggattcttg gtttgatttt
    60541 ctgagatttt caagagactt ttcagagatt ctacgttcag acataacatt ttctttctac
    60601 ttgtcacaac agacggatga tgcttttgtt tcaagggttt tcatgatata attgtaaaaa
    60661 aagacagaac ctttgtcaat gtataactga caaagatgga gaatttctat gacttggaag
    60721 attattgctg actctggttg tgattatcgt caactgccaa caccagctat taacacaacc
    60781 tttgtaagtg tccccttaac cattcaagta gctgatcagg tctttgttga tgacgccagt
    60841 ctcgatattg accaaatgat ggaaaccatg tatgcaactg cagaagcttc aaaatcggct
    60901 tgtccaagcc cagatgacta tttgcgagca tttgaaggtg ccaaaaacat tttcctagta
    60961 accatcacag gtaccctttc tggtagtcac aatagtgctc aactagcaaa gaatatttat
    61021 ctggaagacc atcctgacac taagattcat gtgattgata gtttatctgc tggtggtgaa
    61081 gttgacctac tcgtagaaaa attgaatgac ttgattgacc agggcttgtc ttttgaagaa
    61141 gtggttgaag ctatcaccgc ctatcaagaa aaaactaagt tgctctttgt cctagccaaa
    61201 gtcgataact tggtgaagaa cggccgtttg agcaagctta tcggtacggt cgttggcctt
    61261 ctcaacattc gtatggtcgg aaaagctagt gaaactggaa ctctcgaatt gctacaaaaa
    61321 gcaaggggat caaagaaatc agttcaagct gcctatgatg agttagtaaa agctggatat
    61381 gctggtggcc gtattgtcat ggcccaacgc aataacgaaa aatgttgtca acagctctca
    61441 gagcgaatcc gtgaaacctt cccacaagcg gatattaaaa ttctaccaac ctctggtctc
    61501 tgcagtttct atgcagaaga gggcggtttg ctgatgggct atgaaattga ttaattgcat
    61561 tcttgacaag aggtgaccat catctcttgt ttttttgtgg tacaatagag ctatgaaaca
    61621 ttttgatact attgtcatcg gtgggggacc tgctggtatg atggctacga tttccagtag
    61681 cttttatgga cagaaaaccc tcctcatcga aaaaaatcgg aaacttggaa aaaaattagc
    61741 tgggactggt gggggacgtt gcaatgtgac caacaatggt agcttagaca acctgctagc
    61801 tggaattcct ggaaacggac gctttcttta cagtgttttc tcccagttcg ataatcatga
    61861 catcatcaac ttttttacag aaaatggtgt taaacttaag gtcgaagacc acggacgcgt
    61921 ctttccagcc agtgacaagt ctcggactat tatcgaagct ttggaaaaga aaatcactga
    61981 actaggtggt caagttgcta ctcaaataga aatcgtttct gttaaaaaag tagatgacca
    62041 gtttgtcctt aagtcagcgg atcaaacctt cacttgtgag aaactcattg tcacaacagg
    62101 tggtaagtct tatccttcga ctggttcgac tggttttggt cacgagattg ctcgccattt
    62161 taagcatacc atcaccgagc ttgaggctgc tgaaagtcct ttattaacag attttccaca
    62221 taaagcctta caagggattt ctttggacga tgtgacccta agttatggta agcatgtcat
    62281 cactcatgat ttactcttta cccactttgg tttgtcaggt cctgctgccc tacgcatgtc
    62341 tagctttgtc aaaggtgggg aggttctctc actcgatgtt ttgcctcaac tttctgagaa
    62401 ggacttggtt acatttctag aagaaaatcg ggaaaaatcc ttgaaaaacg ctttaaaaac
    62461 cttgttacca gaacgcttgg ccgaattttt tgtacaagga tatcctgaaa aagtcaaaca
    62521 gctgactgaa aaggaacgag aacaacttgt ccagtccatt aaagaactta aaattcctgt
    62581 aactggaaaa atgtcccttg caaagtcctt tgttaccaag ggtggagtca gtctcaagga
    62641 aatcaatcct aaaacccttg aaagtaagct ggtacctggc ctccactttg caggcgaagt
    62701 tatggatatc aatgcccaca cgggtggctt taacatcact tctgccctct gtaccggctg
    62761 ggtggcggga agtctgcatt atgattaaag attaaaggtt gtgaagaatg aacagaagag
    62821 aggcagtcga atttgttaac atgtgtatga ttaaaaacgg agataaggtc ctggtccaag
    62881 accgagttag tcccgactgg tctggcatta cttttcctgg tggtcatgtt gaacgtggcg
    62941 aatcctttgt cgatgctgtc attcgtgaag tgaaagaaga aactggtctg atcatttcca
    63001 aaccccaact ctgtggtatc aaaaactggt atgacgacaa ggattatcgt tatgtcgtcc
    63061 ttttttacaa gacagaacac tttactggtg aactccagtc ttcagacgaa gggaaagttt
    63121 ggtgggagga ctttgaaaat ctttctcatc taaaacttgc aaccgatgat atgtctgata
    63181 tgcttcgtgt gtttctagaa gaagatctca gtgaattctt ttactacaaa aacggtgacg
    63241 actggcttta tgatttgaag taaaaaatag gctaggaaat tcctagccta ttttttctgc
    63301 atttgtctga acgtaagccg caatggcatc tgacgtgtac tgggctgttc cagaaccaaa
    63361 cttgtcaatg ttttccttaa actctgggtt gtagacgtaa cctttaccga tatgaccgaa
    63421 tacctcaata gagcagtcaa atccataagt gcgaatggct tgcaagagct tggctgcttg
    63481 ctcttggttt tcggttgctg ttgcaggtaa accagcttga agattttgtg ccaaagtttg
    63541 aaagacttgg ttaaaggcgg ccgtagcctc gttttcgtga cctttttggc gttcaagcgc
    63601 ttgtcccatg acttcttgac catatttctc taccgcttct tggtggtatt tttgattgtc
    63661 ttgatagcta aatcccgtga atttttcctc aatggtcatt tttctttctc ctttttgttc
    63721 ttgaatagtt ttttgcaagg tggaaatcaa ggtatccaga tgttgccttt cgcgagttag
    63781 atagtccaac tgcctagtta aatggggcaa taaatctgtc ctttcttcct ttaacagctc
    63841 tgctattttc tctaaagaaa agcctagata tttgtagtaa agaatgacct gaaggcgttc
    63901 caaatcctct tgactatagg ttcgatagcc gttttccgac tttaagggga ccaagagtcc
    63961 tatcttgtca tagtgatgca gggcagggtc ttgacagaga cacctgaaag ctgcgcagct
    64021 tcttttatat ggtacatgat ttcctcctta caatgatagt ataacccctc cccttaggtc
    64081 agagtcaagc gtttttgaga aaggtgtgaa aacttgaaaa tggtttgctt gacagacctt
    64141 agaaaacata ataggatagt caagtctatc aatcaaacag aaggctattt gacaactcaa
    64201 gtagcttttt cttattttga aaaaggagat cagagtttaa ctatgtcaga aaaatcacaa
    64261 tgggggtcga aacttggttt tattctagca tctgctggct ggccatcggg cttggttccg
    64321 tttggaagtt tccctacatg actgctgcta atggcgatgg aggcttttta ctaatctttc
    64381 tcatttccac tattttaatc ggtttccctc tcctgctggc tgagtttgcc cttggccgta
    64441 gtgctggcgt ttccgctatc aaaacctttg gaaaactggg caagaataac aagtacaact
    64501 ttatcggttg gattggcgcc tttgccctct ttatcctctt atctttttac agtgttatcg
    64561 gaggatggat tctagtctat ctaggtattg agtttgggaa attgttccaa cttggtggaa
    64621 cgggtgatta tgctcagtta tttacttcaa tcatttcaaa tccagccatt gccctaggag
    64681 ctcaagcgtc ctttatccta ttgaatatct tcattgtatc acgtggggtt caaaaaggga
    64741 ttgaaagagc ttcgaaagtc atgatgcccc tgctctttat catctttgtt gttatcatcg
    64801 gtcactctct cagcttgtca aatgccatgg aaggggttct ttacttcctc aaaccagact
    64861 tttcaaaact gactagcgct gatctcctct atgctctggg acaatctttc tttgccctct
    64921 cactaggggt tacagtcatg ttgacctatg cttcttactt ggacaagaaa accaatctag
    64981 tccagtcagg aatctccatc gtagccatga atatctcgat atccatcatg gcaggtctag
    65041 ccattttccc agccatgtca gccttcaata tccagtctga agggggaccc agcctgctct
    65101 ttatcgtctt gcctcaactc tttgacaaga tgccttttgg aaccattttc tacgtcctct
    65161 tcctctttgc gactgtcact tcttctgtcg tgatgctgga gatcaatgtg ggcaatgtca
    65221 ccaaccagga taacagcaaa cgtgccaaat ggagtgttat tttaggaatt ttgacctttg
    65281 tctttggcat tccttcagcc ctatcttacg gtgtcatggc ggatgttcac atttttggta
    65341 agaccttctt tgacgctatg gacttcttgg tttccaatct cctcatgcca tttggagctc
    65401 tctacctttc actttttaca ggctatatct ttaaaaaggc tcttgcaatg gaggaactcc
    65461 atctcgatga aagagcatgg aaacaaggac tgttccaagt ctggctcttc cttcttcgtt
    65521 tcttcgtttc gtcattccaa tcatcatcat tgtggtcttc attgcccaat ttatgtaatc
    65581 aaaaagaact tgagtagtga actcaggccc tttcttttta tggatggcta acaatcaatt
    65641 ccaaaccttg cccttccaga gtccaagctt caacatcact tggtaggata aagtggctgc
    65701 ctttttgaat tggataattt ttcccgtcaa cagttagctg accttgacca gctaagacac
    65761 tcaataaact gtagtcagct gtcttttcaa agtcaacttt tccagtaatt tcccacttgt
    65821 aaactgcgaa gaaatcatta gatacaagga gagtggaacg caaatcatct gctttaacag
    65881 ttacaggacg gctatttgct ggctcaccaa tgttcaagac atcgatggat ttttcaagat
    65941 gaagttcacg caagttgcct ttgtcatcct tgcggtcaaa gtcatagacg cgataggtgg
    66001 tatcgctaga ctgctgggtt tcaaggatta agatacccgc cccgatagcg tgcatagtcc
    66061 cgcttggtac atagaagaaa tctccagcct taacagggac tttggtcaac aagtcatccc
    66121 agttcttgtc ctcgatttgc tggcggagtt cttcttttga cttggcattg tgaccgtaga
    66181 taatctctga accttcatcc gctgcgataa tgtaccagca ttctgttttt ccgagttcgc
    66241 cttcatgctc gagtccataa gcatcgtctg ggtgaacttg gacactgagc cagtcgttgg
    66301 catcgaggat cttggtcaaa agtggaaata caggttctgg acgattgcca aataattcac
    66361 ggtgttccgc atacaaagta gcaagatctg ttccctcgta acgaccattt gcaactttag
    66421 agactccatt tggatgggct gagatggccc aatattctcc gattttttca cttgggatgt
    66481 cgtagccaaa ctcatcacgt agcttggctc caccccagat tttttcttgc ataactgatt
    66541 gtaaaaataa tggttctgac atgtcgatct cctgtctgat ttttctcccc tcattatagc
    66601 aaaaaaagag ttcgaattga actctttttt acatcttata aagcagggag aagattttat
    66661 aaaaatagta aacaaatgtg ctctacccga tgcttgcacc attgctatca atgacatcct
    66721 tgtaccaata gaaggacttc ttcttgctac gtttgagagc tccgtttcct acattatctc
    66781 gatctacata gataaagcca tagcgcttat tcatttcccc tgtgccagct gaaactggat
    66841 cgatacagcc ccaagtcgta taaccaagca agtcaacccc gtcttggtaa atggcatctc
    66901 gcatggcctt gatgtgggcc tctaagtaag taatccgata gtcatctgct acataaccat
    66961 tctcatccgg tgtatccata gcacctagtc cattttctac gataatacta aactaaaatc
    67021 aaaaagcatt atataatagt gatatgaaat caactaaaga agaaatccaa gccatcaaaa
    67081 cacttttaaa agactctcgt acagctaaat atcataaacg ccttcaaatc gttctatagt
    67141 aaaacgaaac aagaacaggg caaatcgatc aggacagtca aatcgatttc taacaatgtt
    67201 ttagaagtag aggtgtacta ttctagtttc aatctactat atttcgtctg atgggcaaat
    67261 cttataaaga gattatagat cttttagact gtaatcaaac aacgatttgg cgaaatgtaa
    67321 aaaaatatga ggagttcgga ctcgactctc tccttcaaga aacacgtggt ggtcgtaacc
    67381 atgcatatat gacagttgag gaagagaaag cctttcttgc ccgtcatttg aaggctacag
    67441 aggcaggaga atttgttaca attgatgcct tatttcaggc ttataaaaag gagtgtggat
    67501 gaacgccttt ttagaagagc tttcacaagc ttatcctttt attcgttatg gacaatgcta
    67561 tatggcataa atcaagtacc ttaaatattc cgactaatat tgattttacc tttattcctc
    67621 catacacacc agagatgaac ccattgaaca agtgtggaaa gagattcgta aacgtggatt
    67681 taagaataaa gcctttcgaa ctttggaaga tatcatgaat caacttcaag atgtcataca
    67741 aggactggag aaggaggtga taaagtccat cgttaatcgg agatggacta gaatgctttg
    67801 tgaaagcaga tgagtataag tcctcgtttt gaaaccttag agcaggccat tgcctccaaa
    67861 gatttggaaa aagtccgaga agcttttaag aaaatgaatt ccacttggac catcaatgaa
    67921 agtgtggttc gtgacaatag tacagctcat tatggacgtg ttgaaacagc tatttccttc
    67981 ctgcctagta gcatggaaac cgaacctaca gatgagtctg gaacatgaaa acagcagttg
    68041 atttcaagaa acaaaaaaga acagccgaaa ctgttctctt atcattattt gagaccgtat
    68101 tttttgttga aacgatccac gcgtccatct gcttgagtga acttttgacg tccagtgtag
    68161 aatgggtgtg agtctgatga aatttccaca cggatcaatg ggtaagtttc gccttcgaac
    68221 tcaactgttt cgttagagcg ttttgttgaa ccgctaagga attggtaacc agtagttgtg
    68281 tccatgaaga caactgggcg atattctgga tggatatctt ttttcatttt gcaatatttc
    68341 ctttctgcca tggtctcttt gcgagccata gattgttacc atactagtct atcagattct
    68401 gaaaagtttg gcaagtattt tatcagtttt taagcaagtt ttttaacttt tggtagatga
    68461 tttcgttttc ttctaggcta taggaattag caccacttgc tagagggtgg cctccaccat
    68521 catgctcctt ggcgatttca ttgataggat ggattttact gcgtaagcga actcggtagt
    68581 ggccatcagc ctgttcgaca aaaattcccc agagactcac tctgtcaatg cgtccaggtg
    68641 caccgacaat ggctgcagtt tcagcatcgg ttacattgta ttgtttcaag acttcttgac
    68701 tcaggataac gcgagcagca ccattttcat ccacttccag atggtcgtag atgtagcctt
    68761 gcagtttagc aattttgtag ctcatagtgt ccattttgcg agtgagagcc gcaaagtcaa
    68821 agttatgttc tctcaaataa gcagccaggc gaagagtccg tgcagtggta gaagggtaga
    68881 ggaagcgacc tgtatcaccg acaattcctg caaagagcaa ctcagcatcg cgatctgcca
    68941 aggctagttg ggttgtttgg gcaaataggg taatcatctc gctagcgcta cttgaactag
    69001 tatcgaccca agacaggtca ccgtatacat catcatttgg atggtggtca atcttaatga
    69061 gaaaatcacc ttgactatag cgcttatcat cgatacgagc agtattagct gtatcacaga
    69121 cgatgacaag tgcgccttgg taggctctat cttcaacaag atccatctca gccatccaag
    69181 taagagttgg ttcatcaaaa ccgacggctt tgatggtttt ttctgggaaa tgatgttcca
    69241 gcaaggcttt caatcccacc tgacttccca aggcatcagg gtctggtttc atatgacgat
    69301 gaatgataat ggtgtcgtat tctttaattt tttctaaaat ttgttggcaa atctccataa
    69361 ataacctcaa ttctttctca tttcattgta gcacaagaat ttttattttt aaaatgaaaa
    69421 agatgtgata taatggagaa agataaattg aggaggacga tatggcatta gcaaaaattg
    69481 tatttgccag tatgaccggt aataccgaag aaattgcaga tattgtagca gacaaattac
    69541 gtgacttggg cttggatgtt gatgttgatg aatgtacaac tgttgacgct tcagacttct
    69601 tggaagcaga catcgctatc gttgcgacct atacttatgg tgatggtgaa ttgccagatg
    69661 agatgatgga cttctacgaa gacctagcag atctcaactt gaatggcaaa atctacggag
    69721 tggtcggctc aggagatacc ttctacgatg aattctgtaa ggctgttgat gactttgacc
    69781 gtgtctttgt gtcaacagga gcagaaaaag gttcagagtg tgttaaagtt gatctttctg
    69841 ccgaggaaga agatattgaa cgcttggaac aattcgcaga agaattggct gctaaagtag
    69901 gataagcata aaagtgcgct gatgtaatca atcagtgcat ttttcttatc gagagttggg
    69961 attttactag cctaattgat ggctttttga tacaataatt caaataaagg aggagactgt
    70021 atggatttag atattattcg tcaagaaatc gatcaaatcg acgaccaaat tgtcaaactg
    70081 ttagaagaac gaatgcattt agttgagggg gtggttgctt ataagaaagc ttcaggtaaa
    70141 ccgattttag atactaagag agaagaagtt atttttgaaa aggttaggag tcgtgtagag
    70201 gacaagcgct atcaggagac tattgtagcg actttttcgg acatactcaa acgttcgcgt
    70261 gattatcagg atcaaaatat caaatgaaaa aagaacaatt ttatccgcta ggaatttttc
    70321 tagctgctat gttgggcgga cttgtccgat atctagtttc cacctggtta ccagccagtc
    70381 cagactttcc ttggggcact ctctttgtca actatctggg aattttctgc ttgatttttc
    70441 ttgtcaaggg ctatctggtc tataagggga ctagtaaggg cttgatttta gcactgggga
    70501 cgggtttttg cggaggttta acaacctttt ctagtctcat gcttgatgct gtgaaattac
    70561 tggatacagg gcgttatctt agtttgatac tgtatttgct tttgagtatc ggtggaggcc
    70621 tgcttttagc ttactatttg gggaggaaga aatggtaatc gtctatcttg caatcgcctg
    70681 tggcttggga gcactcgtac ggtatttctt ttcccgctac aatcaagctt ctaaattgcc
    70741 acttggaacg ctcatagcta atcttttagg ttgtttttta attggagtat tctacaatca
    70801 tgtagagtct aaggaagtat atgctattct agcaacagga ttttgtggcg gtttaacaac
    70861 tttttcgacc ttgaatgacg aacttcaaag actgctaagt gataagaagg tcttttattc
    70921 ttacctgact ttgacttaca taggtggttt ggttgcgatt tttttaggaa ttttgctata
    70981 aatttcttta cttttttgtg aaaatttggt agactgtatc ttgtgtgtga tggacgcaca
    71041 aaaatacagt ttatccgctg aggaagtttc ctcaagattg acaaagatag gagaataaaa
    71101 tgaatccatt aatccaaagc ttgactgaag gtcaacttcg tacagatatc ccatcattcc
    71161 gtcctggtga cactgttcgt gtacacgcga aagttgtcga aggtaaccgt gaacgtatcc
    71221 agatttttga aggtgttgtt atcgcacgta aaggtgctgg aatctcagaa aactacacag
    71281 ttcgtaaaat ctctaacggt gtaggtgttg agcgtatctt cccaatccac actccacgtg
    71341 ttgaaaaaat cgaagttgtt cgttacggta aagtacgtcg tgcgaaattg tactacttgc
    71401 gtgctcttca aggtaaagca gctcgtatca aagaaatccg tcgttaattc gactaaaaaa
    71461 ctctgctttt cagcagagtt tttatctagc tcccttagtt caatggatat aacaactccc
    71521 tcctaaggag tagttgcagg ttcgattcct gcagggggca gtaattagac atcaaaaacc
    71581 gctcagctga gcggttttta tctattcttt ccttttacag tacccatgta cgaatagcat
    71641 gggcaacgcc ggattcgtca tttgttttgg tggtgtattt ggcgattttt ttgatttctg
    71701 gatttccgtt ttccatgact acagggttgc caacgacttc cagcatggca cggtcatttt
    71761 cttcgtctcc gatagccatg gtttcatctt tggttaatcc tagtttttca gctaagtgag
    71821 taatagctga acccttgtct acattctttt taaggagttc gaggtagaaa ggagcagatt
    71881 tgttgataga gtagtgctcg taaaattcgg ctggtatttt ttcaatcgca gcatcgagga
    71941 tttctggttc atcgatgaac atacacttga caatttcctt gccagccatt tcttcaggag
    72001 tgcggtagaa gataggcatg ctgacgaggg ttgattcgtg cacagtgtat gttccgatat
    72061 tgcgattggc ggtatagata ccgtccttag taatagcatg catgtgaaca ccaagcttgc
    72121 gactgagaaa ttccatatcc agataatcct cataggtcaa ggattcgctg ataatctcat
    72181 ggccagtatc agtctcttgg acaagggcac cattgaaggt caccacatag tcaccttggt
    72241 ctctcaactg caagtcgtcc agaagtttgg caacacctgc gatggggcgg ccagttgcaa
    72301 tcacgacttt gacaccagct tctttggcat cttggatggc agaaaagact tcaggagtga
    72361 tttccttttg gctgttgact agggttccgt caatatcgac ggcaattagt ttaatactca
    72421 taaaattcct cttctagttt ttatttgggg taaaatgatc gttctcaatc aagtgtaaaa
    72481 attgctgggt aatgcttgca aagatgctgt tttggtccaa catttctttt ggaaaataaa
    72541 agcgattatc tccgtggcga ctgccagcaa gggattggac gataggagac aggctagaga
    72601 gttcggccag ttctccattt ttttgtaaaa tctcaatctg tgtccgtggg ttttcagatt
    72661 cgggacgata gatatcataa gggaggtcaa agttcttatg aatggcagtg tagtagtcgg
    72721 gatcaaagcc gatatcctca accaattttc tcatgctagt aagttgatct tggtcctctt
    72781 gtgaaaaggt aatggattta aagaccttgc ggttgacaaa gcgatgcgat aaatctgcaa
    72841 gaatcttgtc aggactggtc atccaaagct ggaagtaggt attcatcacg ccatcatcca
    72901 gagccagata gtcagtcaag gtcacatttt tttcgaagaa aggcaggagg tgtggagaag
    72961 ttcgggcaaa gaaatccttg tcctcaggat agagttcctt ggcgcgtttg agaagattct
    73021 gtaggagaac ttccatggcg cgtgttgcgg ggtggaaata aacctgcatg tacatctggt
    73081 agcgactgag gacgtagtct tcgatggcgt gcatgccatt gcactgaaag gcgataccat
    73141 tttcgatagg acgaatgact cggaggattc gagtcaggtc aaattcccca taggatgctc
    73201 ctgtaaaata ggagtcacgc aagagatagt ccatgcggtc cgcatcaatc tggctagaaa
    73261 tgagctgcac gacctgctta ttaggatagg tatggtcaat gacactggcc accttttctg
    73321 ggaaatcagg tgccacttgt agcaggactt ggtgaatctc tgtctcagga ttttgaataa
    73381 tctcctgagt aatggcttca tggtctgtat caaagagatt ttcaaaagta tgggagtagg
    73441 cgccatgccc aaggtcgtgt aggagagcag cggtcatggt caagagagac tcggcaggat
    73501 tccattcctc aggatatttt tcttcgaaaa tctctgtgat gcgtcgtgca atttcataga
    73561 ctcctagaca gtgagagaag cgactgtgtt ctccaccgtg gaaggtataa ctggaagttc
    73621 ccagttgttt gatccggcgc aaacgctgaa attcttttgt attaatcaag tcatagatga
    73681 tttgattatt gacatggatg tagttgtgaa ctgggtcacg gaatactttt tcgttcatat
    73741 gaccattata gcaaaatcct gctctttttg gtaaaatagt aggacaagag acaagaaaga
    73801 ggacttgatg tgaagattcg gatgcgaaat acgattcagt ttgatgagca gttggaagtg
    73861 attgaccagc tttatgatgt ggaagtgcat gaaaagggag attatagcta tttactcttt
    73921 tataatgagg aaaaggaaaa agtagttatt aaatttcatg gtcaagaact ggtgatgagc
    73981 cgattttcta atcccaagac cattatgcgc tttttaaagg atagtgatag tttggcctat
    74041 attcctaccc ctatgggcat gcaggaattt atcattcaaa cgagccgtta tcaagttgat
    74101 aggcaaaaga ttgagctagc ttatcaacta caaaatcaag aggggcatcc ctttgccagc
    74161 tatcaattgg aaattacttg gggctaggat ctcgtttttc tcaaatctac tttctatctt
    74221 caaggattgg ctccctagtg tggtagatta ggctattttt tggtataata aaagttatgg
    74281 aaatcgaaaa aaccaatcgt atgaatgcgc tctttgaatt ttatgcggcg cttttgacag
    74341 ataagcaaat gaattatata gagctttact acgctgatga ttacagtctt gctgagatag
    74401 ctgaggagtt tggtgttagt cgtcaggctg tctatgacaa tatcaagcga acagaaaaga
    74461 ttctggaaga ttatgagatg aaattgcaca tgtactcgga ctacattgtc cgtagtcaga
    74521 tttttgacca aatcttggat cgctatccca aggatgattt tctgcaggag cagatagaaa
    74581 ttttaacaag cattgataat agagaataag aggaagaaaa atggcatttg aaagtttaac
    74641 agaacgtttg cagaacgtct ttaaaaatct acgtaaaaaa ggaaaaatct ctgaatctga
    74701 tgtccaagag gcaaccaaag aaattcgctt ggccttgctc gaggccgacg ttgccttgcc
    74761 tgttgtaaag gactttatca agaaagttcg tgagcgtgca gtcgggcatg aggtcattga
    74821 tacacttaat cctgcgcaac agattattaa aatcgttgat gaggaactga cagccgtttt
    74881 aggttctgat acggcagaaa ttatcaagtc acctaagatt ccaaccatca tcatgatggt
    74941 tggtttacaa ggggctggta aaacaacctt tgctggtaaa ttggccaaca aactcaagaa
    75001 agaagaaaat gctcgtcctt tgatgattgc ggcggatatt tatcgtccag ctgccattga
    75061 ccagcttaag accttgggac aacagattga tgtgcctgtc tttgcacttg gaacagaagt
    75121 accagctgtt gagattgtac gtcaaggttt ggagcaagcc caaactaatc ataacgacta
    75181 tgtcttgatt gatactgcgg gtcgtttgca gattgatgag ctcctcatga atgagcttcg
    75241 tgatgtgaaa gtattggctc aaccaaatga aatcttgctt gtcgttgatg ctatgattgg
    75301 tcaggaagca gccaatgttg cgcgtgagtt taatgctcag ttggaagtga ctggggtcat
    75361 ccttaccaag attgatggtg atactcgtgg tggtgctgct ctgtctgttc gtcacatcac
    75421 tggaaaacca atcaagttca ctggtacagg tgaaaaaatt acagatatcg aaaccttcca
    75481 cccagaccgt atgtctagcc gtatccttgg catgggggat atgctcactt tgattgagaa
    75541 agcttctcag gaatacgatg aacaaaaagc ccttgaaatg gctgagaaga tgcgcgaaaa
    75601 cacctttgat tttaatgatt tcatcgatca attagatcag gtgcaaaata tggggccgat
    75661 ggaagacttg ctcaagatga ttccaggtat ggccaacaat ccagcacttc aaaacatgaa
    75721 ggtggatgaa cgccagattg ctcgtaaacg tgccattgtg tcttcgatga catctgaaga
    75781 acgtgaaaac ccagatttgt taaatccaag ccgtcgccgt cgtattgctg ctggttctgg
    75841 aaatacattc gtcgaagtca ataaattcat caaggacttt aaccaggcta aacagctcat
    75901 gcagggtgtt atgtctgggg atatgaataa aatgatgaag caaatgggga ttaatccaaa
    75961 taaccttcct aaaaatatgc caaatatggg aggaatggat atgtctgccc ttgaaggaat
    76021 gatgggacaa ggcggtatgc ctgacttatc agctctcgga ggagcaggaa tgccagatat
    76081 gagccagatg tttggtggcg gtttgaaagg taaaattggt gaatttgcca tgaaacagtc
    76141 catgaaacgt atggctaaca aaatgaagaa agcgaagaag aaacgcaagt aagacaagag
    76201 attgatgcaa atctcatttg atgagaaaat aaagtaaaaa tttctatgat aaaacgtaca
    76261 gtatcaaggt tttagaatat ctgatattat acgttttttg attttaataa ttttgttaag
    76321 acacttttat tatggtatac gaaaaatcca ctcagctgtc tgagtggatt aggtgtattt
    76381 agactcttag tctttatttt cgtatggcaa gatcaagttc aagatgattc ctgtcatggc
    76441 tgaaagggca gtacctgaaa gtgtaactgg accaagttta aggatagctc ctccaagtcc
    76501 aagaaccaac atagcacttg cgatgatgag gtttcgcatt tgagcgaaat caacacgttc
    76561 tttaatcaag actttcaaac cattgctggc gataacccca tagagaagga ttgacatacc
    76621 accaagtaca gcgtttggaa tagttgaaat caaggcagtg aatttaccaa ggaagctgag
    76681 ggcaatcgcg atgaaggcag cgttacggat aactgagaca gaagcgatac gagtcatacc
    76741 gataacccct gtattttctc cgtaagttgt attggctggt ccaccaagga aggcagaaac
    76801 agaagttgcg ataccgtcac caataagagt acggtgaaga cctggttctt ttaagaattg
    76861 acggccacag atttgaccca aaacagtatg gtctccgata tgttcagaaa ttgttacgat
    76921 agcgattggc aagatagcga tggcttctgg accaaagtaa agattgtact ctttaaaggc
    76981 accacctgtg ctaaatggca agtagaaacc aggaatttcg aaccagttgg ctttaagaac
    77041 tggtgtaaag tcaaccaagc caagagttag tgcgaaaagg taaccaccga taatggcaaa
    77101 gaggaatgga atgattcgta ggaagccttt tccttttgta ttgataaagg cagcaattag
    77161 gaaagtaaca acggctacca gagcattttt ccaatttccg tctgctacaa gacctgcatt
    77221 ggtaacagct gaacctgcaa gtccaagacc gataacgatg atcataggac cgataatgat
    77281 tggtggcaag agtttatcaa tccattttgt tcctacaaat cggatgctgg tagcaacaag
    77341 gacatagacc aaaccagtca agataacccc tgtttgggca gcagatacat ccccccccat
    77401 ttctttcata gccagtgaca tagctgtgat aaaggcaaat gaagaaccta gataaactgg
    77461 aactttaaaa ccagtagcaa tcatgtagat gagtgttcca acacctgaag caaagagggc
    77521 aacagataca ggcattccca aaatcaatgg taccaagatg gtcgcaccaa acatggcgaa
    77581 aacgtgttgg aagctaagga gaattccttt tccatccgaa ggacgttggt caacgtctag
    77641 taacaaatca acagttgatt cttgtttcat ataaacctca cttttgggca tcagaaaaga
    77701 gcccattatt ttacagcaat aggccctcag agtaagactt ctctaaaatc tagactttaa
    77761 agagtttcaa atatttttgc gtcttcgtca cctcacggga tgacattaaa aacctttgct
    77821 taggatagta tagcagaaaa aaatgatttt gtaaatcatt ttttcccgag cctagaaata
    77881 aaagagcgag gctgattttg taaacatttg tttactaaaa aatttaaagt gggcgtttat
    77941 ttggcatacc agccttacgt ggatatttat ttggtgtttc ttttttcttt tctaccactg
    78001 tgatatagcg cggatctcta ttcggtaggg cgtagctgag attgtcttcg accttactaa
    78061 aaaggagatt gagggcattc ttagcttcta ataattcctc aggcgcattg ctggccttga
    78121 gtgccaatag tttgccacca accttaaggt agggaatagt caattcagat aggacctgca
    78181 tacgggcaac cgcacgagct gttacaaaat catattgagc acggaagttc ttgtcttggg
    78241 caaaatcttc ggcacgtccg tggtagaaat gaactccgtt caaatccagt tcttgagcca
    78301 agagttgtag gaagttgatg cgcttattga gtgaatcaat aatggtcaca tctaactccg
    78361 gatagagaat tttcattggt agactaggaa atcctgcccc agccccgata tcaagaagtt
    78421 tgatagtttc attgggaatc aaaccttgaa gaatgggtgc aatcgaatcg taaaaatgtt
    78481 tgagataaac ttcttccttg tccgtaatcg ccgtcaaatt aatcttctca ttccactcga
    78541 ccaagagctc aaaataacgt tcaaattgtt ctttttgctg gttcgaaagt ggaagatttt
    78601 gctcggcaag caagttgtaa aatgtttctg gtttcatagt tatttccttc tttagtatca
    78661 tcttatttta ccacaatcat taaaaatttg atatactggt actaatctaa aagtagaaag
    78721 gacttatatc atgacttgga ttattcttgg agttatcgct cttattgttg tttttgtgat
    78781 tgttagctat aacggtttgg ttaaaaatcg tatgcaaacc aaggaggctt ggagtcagat
    78841 tgatgttcag ttgaaacgtc gaaatgacct cttgccaaac ttgattgaga ctgtaaaagg
    78901 ttatgccaaa tatgaaggtt ctacccttga aaaggtggca gaactacgta accaagtggc
    78961 ggcagcgact tcaccagcag aagctatgaa agccagtgat gccctcactc gtcaggtttc
    79021 aggtattttt gcagttgcag aaagctatcc agatttgaaa gctagtgcta actttgttaa
    79081 attgcaagag gagttgacaa atacagaaaa taaaatttct tactctcgtc aactctataa
    79141 cagtgttgtc agcaactaca atgtaaaatt agaaactttc ccgagcaata ttatcgctgg
    79201 aatgtttgga tttaaagcgg cagatttcct tcaaacacct gaagaggaaa agtcggttcc
    79261 taaagttgat tttagcggtt taggtgacta agatgttgtt tgatcaaatt gcaagcaata
    79321 aacgaaaaac ctggattttg ttgctggtat ttttcctact cttagctctt gttggttatg
    79381 cggttggtta tctctttata agatctggac ttggtggttt ggttatcgca ctgattatcg
    79441 gctttatcta cgctttgtct atgatttttc aatcgacaga gattgtcatg tccatgaatg
    79501 gagcgcgtga ggtggatgag caaacggcac cagacctcta ccatgtagtg gaagatatgg
    79561 ctctggtcgc tcagattcct atgccccgta ttttcatcat tgatgatcca gccttaaatg
    79621 cctttgcgac aggttctaat cctcaaaatg cggctgttgc tgcgacttca ggtctactag
    79681 ctatcatgaa tcgtgaagaa ctagaagctg ttatgggaca tgaagtcagt catattcgta
    79741 attatgatat ccgtatttcg actattgcag ttgcccttgc tagtgctatc accatgcttt
    79801 ctagtatggc aggtcgtatg atgtggtggg gtggagcagg tcgcagacga agtgatgatg
    79861 accgagatgg aaatggtctt gaaatcatta tgctagtggt ttccctacta gctattgtac
    79921 tggcacctct cgctgcaacc ttggttcagc tcgctatttc tcgtcagagg gaatttctgg
    79981 cagatgcatc tagtgtcgag ctgactcgca atccccaggg aatgattaat gccctagata
    80041 agttggacaa tagcaaacct atgagtcgcc acgtcgatga tgctagcagt gccctttata
    80101 tcaatgctcc caagaaaggt gggggggtcc aaaaactctt ttatacccac ccacctatct
    80161 cagaacggat tgaacgttta aaacagatgt aaaatgaagg ctggaaaaaa gtctttaaaa
    80221 tctgaaaaat gcataatatc aggtgtgaaa acttgatatt atgcgtttta ctatgggaag
    80281 atttacttct ttttctccta aaattgtgtt tttgccccac ctatctgcta tgttgcaaat
    80341 ttataaatct tctaaattaa ctagcttcaa accgtgttct gtcatgcgac agatgatcga
    80401 gcagacttct tttaagaaac gacggtcatg cgaaacagtg atgagaccgc ctggataggt
    80461 tgcaaagagt tttctgattt ggggttgaga agtgggagaa aagtttcgtg tgggttcatc
    80521 cagcaggaga aagtttggtt tgcgcaggac tagatccaaa agcaggagtt ttccctgttg
    80581 tccgccagat aaggagcgaa tttgatgctg catttctgga taactgaaat tgagactggc
    80641 taggtgagat tgaattttct gaagttcctc tttttcccca gttttgctga tataagctat
    80701 tggtgataaa tccaattgta gttttttgtg gtaatcttgt ggcataaaac caagggaaat
    80761 ctctctttta tcattcagaa gttgctttaa tttggctaac agagttgatt tcccaacacc
    80821 atttggcccg ataataccga ttttttcttg cccacggaca gttagttgta gtttttgaac
    80881 caaaactcgg tcgtcaatgg acaaattttc tttttccagt tggactaaga ctttagaagc
    80941 tggtaatggt tggatatctg aaaagaaaag ttggatttgt tcctcttcaa gtggtttttg
    81001 agtcatggac tgagctgcct tttcgtagcg tttttcttgt gagaggacag ttttcatctt
    81061 tttagccaat aggcgaccgg cagtactatc tttggtagct cgaagcgcag tttctacatt
    81121 ttgcttaact ctccgatgtt tttccatggt tttatcgtag gctctttggt tgttagcagc
    81181 ttgctgactt tgtttggcaa aattagcctt tctctgctca ctatagctat catagtctaa
    81241 atgctctact agcgtttccg cttctttacg gtgtttgacc agtcgcaagt gaacaatagt
    81301 gtctgccgtt tcagaaagaa agtcttcatc atgggaaatg aaaataacgg tttgcctggt
    81361 cttttgaatc tggcctttta gccaatcaac tgtctcaagg tctaggtcat ttgaaggttc
    81421 atctaaaaat agaatctcaa agggtttggc taactcatgg ataagctgaa ttttcaaagc
    81481 ttctccccct gatagattgc caatctcttg gtcacttgcg aaacgattgc tatcaaaatg
    81541 caattcctcc gccaaacgat agaggatact gtagtctaaa tcaatagaat ctaaaaagaa
    81601 gtagtcgtgt aaagttttct ttttcagctc ctcgggaagt ttttgaggaa tgtaggccag
    81661 tgactgatag tcagattgga tgtttccctt gatagtgaaa tcagacaaag cttcccccat
    81721 taaaatttta agtaaggttg atttgccatt tccttcttca ccaataatag caaccttttc
    81781 cccgtcttgg atggtcatgc ttaggtcaga tacaagatct cgtaaatctt tgttttgtgt
    81841 gatggttaga tgattgattt ttatcatatg atttcccttt ctagaatgtt catagtgcat
    81901 aacaaaaagc tctactttac ctagtagagc ccaaagtcta tgtcaaaaaa actctattaa
    81961 catgccagaa aaagagcata aaagagcaca caaaaagaga caaaaacaag atctactaaa
    82021 taaaggttct ttatttgata gacttagttg ttcatgtctc ccttacctcc gagtattagt
    82081 atctttatat tataccttta aggaaatttt gtcaacagaa aactggaaat tctatgctct
    82141 aaaattcaaa aacaggtcta tagagactta gtacgtgttt gacatgctcg taatggaatt
    82201 tatcatagtt tcgccaagca gtgcgtgctt gatcgtttag ttttaggcta cccagtccaa
    82261 tcagaagact ggtgggttgg taaaatttct caagatcaat taagatactg ttgttcaact
    82321 gttccgtttt tttgagctct tgcatagtag tgtttagcag ctcttgtagt cgaatatcat
    82381 ctgccgtacc ctgtttacag ttttggtagc ttttatttaa cttggatagg agttgaatga
    82441 gtttcttgtc ttccatgtga gcatcctcct tgatctgatg tactctttcc ctatagtata
    82501 gcactaaaaa acaaaactgt catagtaaat atgttaaagt tttgaatttt aattacaaag
    82561 tttggtgtgc tgatttgtag ccttttcatg gtataatcaa gagagtaaat ctttatggag
    82621 gaagtatgaa attaaatatt caagaaattc gtaagcagtc tgaaggtttg aactttgaac
    82681 aaacgttaga tttagttgat gacctgcgtg cacgtaatca agaaatttta gatgtaaaag
    82741 atatccttgc agttgggaaa gtacaatatg aagaccgtat gtatttctta gattatcaac
    82801 tatcttatac cattgttctt gcttcgagtc gcagtatgga gccagttgag ttagttgaat
    82861 cttatccagt cacggaagtt ttcatggaag gcgcaactaa ccagctagat caagaagttt
    82921 tagatgatga cttggtcttg cccatcgaaa atggggagct tgaccttgct gagagtgtat
    82981 cagacaatat cctgctaaac attcctatca aggtcttgac ggctgaagaa gaagctggtc
    83041 aaggatttat ctcaggaaat gactggcaaa tcatgacaga ggaagaatac caagctcaaa
    83101 aagcagtaaa gaaagaagaa aacagtcctt ttgctggctt acaaggacta tttgacggag
    83161 atgaataatg atcttgtcaa aaaaacgagc acgaaaggtg ctagaagaaa tcattgccct
    83221 cttcccagat gccaagccta gtcttgattt taccaatcat tttgaactcc tggttgcggt
    83281 catgttatca gcccagacga cagatgcagc ggtaaataag gccacaccag gtctctttgt
    83341 tgtctttcca acaccccaag ctatgtctgt agcgacagag agtgagattg cttcacatat
    83401 ttctcgcttg ggattgtatc ggaataaagc taaattcctt aaaaaatgtg cccaacagtt
    83461 actagacgat tttgatggtc aagtccctca gacacgtgaa gaattggaga gtttggcagg
    83521 tgttggtcgc aagacagcca atgttgtcat gagtgtagga tttgggattc cagcctttgc
    83581 agtggatact catgtggagc gtatttgcaa acaccacgat attgtcaaaa aatcagcgac
    83641 gccacttgag gtggaaaagc gggtcatgga tatcttgccg cctgagcagt ggttagctgc
    83701 ccatcaggcc atgatttatt ttggaagagc catttgccat ccaaaaaatc cagagtgtga
    83761 ccagtaccca caattatatg attttagcaa tttgtaagat gctacattga aactttttgc
    83821 ttgattttaa gcatgctttg tgctatagta aatgataact aaatattcct ttaaacctgt
    83881 cccgtgaggc aggcaaggag cgcgataaag tagaagggtg aagtctatac tgtgtgcagt
    83941 agggctcgct tggctataaa tttcaagtct ccttgtttaa ggagactttt ctttttggag
    84001 gtttgtcatg aaaacaaaag aagttgtaga cgaattgacc gtcaaacgag cgattacgcg
    84061 tattacttat gagattatcg aacgcaacaa agatttgaat aagatcgtct tggctggtat
    84121 taaaactcgt ggtgtcttta ttgcccaccg aatccaagaa cgtttgaagc agttagaaaa
    84181 tctttcagtt cctgttgtgg aattggatac taaacctttc cgtgatgatg ttaaaagtgg
    84241 agaagatact tctttggttt ctgtcgatgt gacagaccgc gaagttatct tggtggatga
    84301 tgtgctctat acaggtcgta ccatccgtgc tgctattgat aatattgtcg gtcatggtcg
    84361 tcctgcgcgt gtgagtttag cagttctagt cgatcgtgga catagagaat tgccaatccg
    84421 tccagattac gttggaaaaa atatcccaac cagtcgttct gaagaaatca tcgtagagat
    84481 gacagaactt gatgaccaag acagagttct gattactgaa gaagcttaga aagttaaagg
    84541 agtagccatg tcagaaaatc aacaagcatt gaaccatgtg gtgtccatgg aagacctcac
    84601 tgttgatcaa gtaatgaaat tgatcaagcg aggaattgag tttaaaaatg gagcccagat
    84661 tccctatgaa gaccatccga ttgtttccaa tctcttcttt gaggattcta cacggacaca
    84721 taagtccttt gaagtcgcag agattaaact tggattggaa cgacttgact ttgatgtgaa
    84781 gactagttcg gttaataagg gtgagacact ttatgacacc attttgactc tgtctgcttt
    84841 aggagtggat gtctgtgtga ttcgccatcc agaggtcgac tactatagag aattgattgc
    84901 tagtccaacg attacgactt ccatcatcaa tggtggagat ggttctggcc aacaccctag
    84961 ccagagcttg cttgatttga tgaccattta tgaggaattt ggccactttg agggtcttaa
    85021 agttgctatt gcaggtgact tggaccactc acgcgttgcc aaatccaata tgcagatttt
    85081 gaaacgcttg ggagctgaac tctttttctc tggacctgag gaatggagaa gtcaagagtt
    85141 tgcagactat ggacagtttg taaccattga tgaaatcatt gatcaggttg atgtcatgat
    85201 gtttctccgt gtgcaacacg aacgccatga tagtggagct gtattttcaa aagaagacta
    85261 ccatgcccaa catggcttga ctcaagaacg ttacgatcgt ttgaaagaaa cagcaatcct
    85321 catgcaccca gctccaatca atcgtgatgt agaaatagca gaccacttgg ttgaagcacc
    85381 aaaatcacgg attgtccaac aaatgaccaa tggtgtcttt gttcgaatgg caatcttaga
    85441 atccgtacta gcgagtagaa acgccaacta aaacacaaga cgttaaaaga cgccagtgag
    85501 cgtccacgag aggtgaaaat atgacaaaaa gaattctagt attagaagat ggcacagttt
    85561 ttgaaggcaa ggccttcgga gcagatattg atgtaacagg cgaaatcgtc tttaatacag
    85621 ggatgaccgg ctaccaagaa tccattacag accagtctta taatggacaa atcttgacct
    85681 ttacttatcc tttggtagga aattatggta ttaatcgtga tgattatgaa tccattattc
    85741 caacttgtaa gggagtcgtt gtttttgaag aagcgcgtag agctagcaac tggcgcaacc
    85801 aaatgacctt ggatgaattt ttgaaagcca agaaaattcc agggatttca ggaattgata
    85861 cgcgtgctct taccaagatt atccgtaagc atggtactat gcgtgcaacc ttgacccatg
    85921 ttggggacag tatggaccat gtgacggacc agctccaagc aacagtttta ccgacagaca
    85981 atatcaaaca ggtttctact aaaacgtctt atccagctcc aggagttggt ttgagcgtgg
    86041 tgctagtgga ctttggtctc aagcactcaa tcctacgtga actttctaaa cgcaactgta
    86101 acgtgacagt tgttccttat tcgacaacgg ctgaagaaat tctccatctc aatcctgacg
    86161 gagttatgtt gtcaaatggt ccaggtaacc cagaagacgt tccacaagca ctcgacatga
    86221 ttcgcggtgt acaaggaaaa attccaatct ttggtatttg tatgggacac caactctttg
    86281 caatggcaaa cggggctaag acctataaga tgaagtttgg ccaccgtgga ttcaaccatg
    86341 cggtacgtga aatcgcaaca ggacgagtag acttcaccag ccagaaccat ggttatgcag
    86401 tcagccgcga ggatttgcca gagcacttga ttattaccca cgaagaaatc aatgacaagt
    86461 cagtggaagg tgtgcgccac agataccaac ctgctttctc tgttcaatac cacccagatg
    86521 cagctcctgg gccacacgac gctagctact tatttgacga gtttatcgag atgatggaag
    86581 tttttaaaca atcaaactaa gaacgagtaa aagctcgtcg gagaatttat gtaactgaac
    86641 acggacggaa agctcagaat ttagagaaac caacttggat tgtcaatcct tccttgattt
    86701 cctaaaaatc aatcgctttc tattcgtcct ttgtatctta tttaatgtcg ccctgagagg
    86761 ctacgaatag aaaggagaag ggtgctccgt atttgctgaa ctgaatacgg gctacggacg
    86821 gtgctaaaaa gatagttatt cctagaactg acagttcttc gtcataactc ctattttagc
    86881 tttgtccgct tgacgccctt aatatcttat atatgcctaa acgtactgat attcaaaaaa
    86941 ttatggtgat tggttctggt ccgattatta ttggtcaggc tgctgagttt gactacgctg
    87001 ggacccaggc ttgcttgtcg ttgaaagagg aaggttatga ggttgttttg gttaactcaa
    87061 atcctgcaac catcatgacg gacaaggaaa ttgctgataa ggtttacatt gaaccgatta
    87121 cacttgagtt tgtgacacgt attcttcgta aggaacgtcc agatgccttg ctaccaacac
    87181 tcggtggtca gacaggtctc aacatggcca tggaattgtc taaaaatggt atcttagatg
    87241 agcttagcgt tgaacttctg ggtactaaat tgtctgccat tgaccaagcg gaggaccgtg
    87301 acctctttaa acaattgatg gaagagcttg agcaacccat tccagaatct gaaattgtta
    87361 acacagtaga agaagcagtt gcctttgcag cgacaattgg ctacccagtc atcgttcgtc
    87421 cagcctttac ccttggtggt actggtggtg gtatgtgtgc caacgagaaa gaattgcgtg
    87481 aaatcactga aaatggtttg aaattgtcac ctgttaccca atgtttgatt gagcgttcga
    87541 ttgccggttt caaggaaatt gaatacgaag tgatgcgtga ctcagctgac aatgccttgg
    87601 ttgtttgtaa catggaaaac tttgacccag ttgggattca cacaggggat tccattgtat
    87661 ttgcccctgc gcaaaccatg tcagactatg aaaaccaaat gcttcgtgat gcgagcttga
    87721 gcattattcg tgccctcaag attgaaggtg gatgtaatgt tcagctagct cttgatccta
    87781 acagcttcaa gtattatgtt atcgaagtaa accctcgtgt atcacgttcg tcagcccttg
    87841 cttctaaagc gacaggatat ccgattgcta agttggctgc caagattgca gtaggtttga
    87901 ccttggatga ggttataaac ccagttacag gttcaaccta tgccatgttt gaaccagccc
    87961 ttgactacgt agttgctaag attccacgtt tcccatttga caagtttgaa aagggtgaac
    88021 gccgtctcgg tacacaaatg aaggcgactg gagaagtcat ggcaatcggt cgtaacatcg
    88081 aggaatctct tctcaaggcc tgccgctccc ttgaaattgg ggtgcaccac aatgaaatac
    88141 ctgaacttgc agtagtttct gatgatgcct tgattgaaaa ggttgtcaaa gcccaagatg
    88201 accgtctctt ctacgtatca gaagcaattc gtcgtggcta cacacctgaa gaaattgcag
    88261 agcttacaaa aattgatatc ttctatcttg ataaactctt gcatatcttt gaaattgagc
    88321 aagaattggg tgctcatcca caagatctag aagttttgaa aacagccaaa cttaatggtt
    88381 tttcagaccg taagattgct gaactctggg gaacgactga tgataaagtt cgccaacttc
    88441 gcttggaaaa caagattgtt ccagtttata agatggtaga cacatgtgcg gcagagttcg
    88501 actccgaaac gccatatttc tattcaacct atggttggga aaatgaatct atcagatctg
    88561 ataaagaatc tgtacttgtc ctaggttcag gtccaatccg tatcggtcaa ggggttgagt
    88621 ttgactacgc aaccgttcac tctgttaagg ctatccaggc agctggttat gaagctatca
    88681 tcatgaactc aaacccagag accgtttcaa cagacttctc tgtatcagat aagctttact
    88741 ttgagccatt gacattcgaa gatgttatga acgtcattga cttggaacaa ccaaagggag
    88801 ttatcgttca gttcggtggt caaacagcca tcaaccttgc ggagccattg gcaaaagcag
    88861 gtgtgaccat ccttggtaca caggttgctg acctagaccg tgccgaagac cgtgacctct
    88921 tcgagcaagc tctcaaagaa ttggatattc cacagccacc aggacaaacg gctaccaatg
    88981 aagaagaagc agctcttgca gctcgtaaga ttggcttccc agttcttgtc cgcccatctt
    89041 atgtacttgg tggacgtgcc atggaaatcg ttgaaaacga agaagatctt cgttcttaca
    89101 tgcgaactgc tgttaaggct agtccagacc acccagttct tgtcgactct tatatcgttg
    89161 ggcaagagtg cgaagttgat gccatttcag atggtaaaaa tgtactcatt cctggtatca
    89221 tggagcatat cgaacgtgct ggtgtccact caggtgactc aatggctgtt tacccaccac
    89281 aaaccttgtc gcaaaaggtt caggagacca tcgcagacta caccaaacgc ttagcaatcg
    89341 gtcttcactg ccttggaatg atgaacatcc agtttgttat caaggatgaa aaagtctacg
    89401 ttattgaggt caatccacgt gccagccgta ccgttccatt cctatctaag gtaaccaata
    89461 ttcctatggc tcaagtagcg accaagctca ttcttggtca aagtttatca gaacttggct
    89521 accaaaatgg actttaccct gaaagcaccc gtgttcatat caaggcacct gtcttctcct
    89581 ttaccaaact agctaaggta gacagcttgc tcggtcctga aatgaagtca acaggtgaag
    89641 ttatgggttc tgatgctact ttggaaaaag ctctctataa agcctttgaa gcttcttatc
    89701 tacacttgcc aacttttggt aatgtcgtct ttaccatcgc tgatgatgcc aaagaagaag
    89761 ccttgaactt ggctcgtcgt ttccaaaaca ttggttatgg aatccttgcg acagaaggga
    89821 cagcagcctt ctttgctagt catggcttgc aagcccaacc tgttggtaag attggtgatg
    89881 acgataagga tatcccaagt tttgtacgca aaggaagaat tcaagctatc attaacacag
    89941 taggaacaaa acgaactgct gacgaagatg gtgagcaaat tcgtcgttca gccattgaac
    90001 acggggtgcc cctcttcaca gcgctagata cagctaatgc catgcttaag gtacttgaaa
    90061 gtcgtagctt tgttacagaa gcgatttaaa tagaaaaata agatatagca gactgaattt
    90121 agaaca
//
LOCUS       DAVKAU010000003        68102 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVKAU010000003 DAVKAU010000000
VERSION     DAVKAU010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.003"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            42..157
                     /gene="rrf"
                     /locus_tag="VWX48_000216"
     rRNA            42..157
                     /gene="rrf"
                     /locus_tag="VWX48_000216"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            162..234
                     /locus_tag="VWX48_000217"
     tRNA            162..234
                     /locus_tag="VWX48_000217"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:195..197,aa:Val,seq:tac)
     gene            237..309
                     /locus_tag="VWX48_000218"
     tRNA            237..309
                     /locus_tag="VWX48_000218"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:270..272,aa:Asp,seq:gtc)
     gene            334..406
                     /locus_tag="VWX48_000219"
     tRNA            334..406
                     /locus_tag="VWX48_000219"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:367..369,aa:Lys,seq:ttt)
     gene            412..493
                     /locus_tag="VWX48_000220"
     tRNA            412..493
                     /locus_tag="VWX48_000220"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:446..448,aa:Leu,seq:tag)
     gene            512..584
                     /locus_tag="VWX48_000221"
     tRNA            512..584
                     /locus_tag="VWX48_000221"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:545..547,aa:Thr,seq:tgt)
     gene            607..678
                     /locus_tag="VWX48_000222"
     tRNA            607..678
                     /locus_tag="VWX48_000222"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:639..641,aa:Gly,seq:gcc)
     gene            686..771
                     /locus_tag="VWX48_000223"
     tRNA            686..771
                     /locus_tag="VWX48_000223"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:720..722,aa:Leu,seq:taa)
     gene            781..854
                     /locus_tag="VWX48_000224"
     tRNA            781..854
                     /locus_tag="VWX48_000224"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:815..817,aa:Arg,seq:acg)
     gene            870..943
                     /locus_tag="VWX48_000225"
     tRNA            870..943
                     /locus_tag="VWX48_000225"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:904..906,aa:Pro,seq:tgg)
     gene            949..1022
                     /locus_tag="VWX48_000226"
     tRNA            949..1022
                     /locus_tag="VWX48_000226"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:983..985,aa:Met,seq:cat)
     gene            1036..1109
                     /locus_tag="VWX48_000227"
     tRNA            1036..1109
                     /locus_tag="VWX48_000227"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1070..1072,aa:Ile,seq:cat)
     gene            1120..1209
                     /locus_tag="VWX48_000228"
     tRNA            1120..1209
                     /locus_tag="VWX48_000228"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1156..1158,aa:Ser,seq:tga)
     gene            1223..1296
                     /locus_tag="VWX48_000229"
     tRNA            1223..1296
                     /locus_tag="VWX48_000229"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1257..1259,aa:Met,seq:cat)
     gene            1300..1372
                     /locus_tag="VWX48_000230"
     tRNA            1300..1372
                     /locus_tag="VWX48_000230"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1333..1335,aa:Phe,seq:gaa)
     gene            1392..1462
                     /locus_tag="VWX48_000231"
     tRNA            1392..1462
                     /locus_tag="VWX48_000231"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1424..1426,aa:Gly,seq:tcc)
     gene            1498..1571
                     /locus_tag="VWX48_000232"
     tRNA            1498..1571
                     /locus_tag="VWX48_000232"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1532..1534,aa:Ile,seq:gat)
     gene            1578..1665
                     /locus_tag="VWX48_000233"
     tRNA            1578..1665
                     /locus_tag="VWX48_000233"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1612..1614,aa:Ser,seq:gct)
     gene            complement(1799..2236)
                     /locus_tag="VWX48_000234"
     CDS             complement(1799..2236)
                     /locus_tag="VWX48_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9170936.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(2443..3378)
                     /locus_tag="VWX48_000235"
     CDS             complement(2443..3378)
                     /locus_tag="VWX48_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU9170937.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(3375..4235)
                     /locus_tag="VWX48_000236"
     CDS             complement(3375..4235)
                     /locus_tag="VWX48_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9170938.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVVFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            4343..6505
                     /locus_tag="VWX48_000237"
     CDS             4343..6505
                     /locus_tag="VWX48_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU9170939.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            6540..7799
                     /locus_tag="VWX48_000238"
     CDS             6540..7799
                     /locus_tag="VWX48_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9170940.1"
                     /translation="MEWYKKIGLLATTGLALVGLGVCSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKEQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            7813..8679
                     /locus_tag="VWX48_000239"
     CDS             7813..8679
                     /locus_tag="VWX48_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9170941.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDSKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LGWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            8693..9526
                     /locus_tag="VWX48_000240"
     CDS             8693..9526
                     /locus_tag="VWX48_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9170942.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            9837..11279
                     /gene="gtfA"
                     /locus_tag="VWX48_000241"
                     /pseudo
     CDS             9837..11279
                     /gene="gtfA"
                     /locus_tag="VWX48_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
     gene            11417..12610
                     /locus_tag="VWX48_000242"
     CDS             11417..12610
                     /locus_tag="VWX48_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU9170943.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            13298..15277
                     /locus_tag="VWX48_000243"
     CDS             13298..15277
                     /locus_tag="VWX48_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9170944.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTNSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            15344..16840
                     /locus_tag="VWX48_000244"
     CDS             15344..16840
                     /locus_tag="VWX48_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9170945.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            16840..17766
                     /locus_tag="VWX48_000245"
     CDS             16840..17766
                     /locus_tag="VWX48_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9170946.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVVKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            17775..18842
                     /locus_tag="VWX48_000246"
     CDS             17775..18842
                     /locus_tag="VWX48_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170947.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18853..19779
                     /locus_tag="VWX48_000247"
     CDS             18853..19779
                     /locus_tag="VWX48_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170948.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(19854..21180)
                     /locus_tag="VWX48_000248"
                     /pseudo
     CDS             complement(19854..21180)
                     /locus_tag="VWX48_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21335..22045)
                     /gene="treR"
                     /locus_tag="VWX48_000249"
     CDS             complement(21335..22045)
                     /gene="treR"
                     /locus_tag="VWX48_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU9170949.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            22230..24197
                     /gene="treP"
                     /locus_tag="VWX48_000250"
     CDS             22230..24197
                     /gene="treP"
                     /locus_tag="VWX48_000250"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU9170950.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24375..26000
                     /gene="treC"
                     /locus_tag="VWX48_000251"
     CDS             24375..26000
                     /gene="treC"
                     /locus_tag="VWX48_000251"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU9170951.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            26256..26504
                     /locus_tag="VWX48_000252"
     CDS             26256..26504
                     /locus_tag="VWX48_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU9170952.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26711..27505
                     /gene="racE"
                     /locus_tag="VWX48_000253"
     CDS             26711..27505
                     /gene="racE"
                     /locus_tag="VWX48_000253"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU9170953.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27502..28473
                     /locus_tag="VWX48_000254"
     CDS             27502..28473
                     /locus_tag="VWX48_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU9170954.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28449..28970
                     /locus_tag="VWX48_000255"
     CDS             28449..28970
                     /locus_tag="VWX48_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU9170955.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28967..29428
                     /locus_tag="VWX48_000256"
     CDS             28967..29428
                     /locus_tag="VWX48_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9170956.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29419..30159
                     /gene="xerD"
                     /locus_tag="VWX48_000257"
     CDS             29419..30159
                     /gene="xerD"
                     /locus_tag="VWX48_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU9170957.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30159..30887
                     /locus_tag="VWX48_000258"
     CDS             30159..30887
                     /locus_tag="VWX48_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU9170958.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLTFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30906..31475
                     /locus_tag="VWX48_000259"
     CDS             30906..31475
                     /locus_tag="VWX48_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU9170959.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31462..32184
                     /locus_tag="VWX48_000260"
     CDS             31462..32184
                     /locus_tag="VWX48_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9170960.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            32184..32426
                     /gene="yidD"
                     /locus_tag="VWX48_000261"
     CDS             32184..32426
                     /gene="yidD"
                     /locus_tag="VWX48_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU9170961.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(32651..33616)
                     /locus_tag="VWX48_000262"
     CDS             complement(32651..33616)
                     /locus_tag="VWX48_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9170962.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALTILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33712..34464)
                     /locus_tag="VWX48_000263"
     CDS             complement(33712..34464)
                     /locus_tag="VWX48_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9170963.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(34461..35417)
                     /locus_tag="VWX48_000264"
     CDS             complement(34461..35417)
                     /locus_tag="VWX48_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU9170964.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(35407..36366)
                     /locus_tag="VWX48_000265"
     CDS             complement(35407..36366)
                     /locus_tag="VWX48_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9170965.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36789..37490)
                     /locus_tag="VWX48_000266"
     CDS             complement(36789..37490)
                     /locus_tag="VWX48_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEU9170966.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DDSCIRDYIYVLDLA"
     gene            37891..38955
                     /gene="pepA"
                     /locus_tag="VWX48_000267"
     CDS             37891..38955
                     /gene="pepA"
                     /locus_tag="VWX48_000267"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU9170967.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38977..39273
                     /locus_tag="VWX48_000268"
     CDS             38977..39273
                     /locus_tag="VWX48_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9170968.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39955..40398
                     /locus_tag="VWX48_000269"
     CDS             39955..40398
                     /locus_tag="VWX48_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9170969.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            40402..41166
                     /locus_tag="VWX48_000270"
     CDS             40402..41166
                     /locus_tag="VWX48_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU9170970.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAVFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            41181..41909
                     /locus_tag="VWX48_000271"
     CDS             41181..41909
                     /locus_tag="VWX48_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170971.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            41902..43422
                     /locus_tag="VWX48_000272"
     CDS             41902..43422
                     /locus_tag="VWX48_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU9170972.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTV
                     LLGLSYSPALLVQKEKENVIIAGKIGPEPEILANMYKLLIEENTSLTATVKPNFGKTT
                     FLYEALKSGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVSTLEPALRYQAIQSGEIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELETVLNKLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            43767..44573
                     /locus_tag="VWX48_000273"
     CDS             43767..44573
                     /locus_tag="VWX48_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU9170973.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(44740..45276)
                     /locus_tag="VWX48_000274"
     CDS             complement(44740..45276)
                     /locus_tag="VWX48_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9170974.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            45409..46299
                     /locus_tag="VWX48_000275"
     CDS             45409..46299
                     /locus_tag="VWX48_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU9170975.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            46543..46896
                     /locus_tag="VWX48_000276"
     CDS             46543..46896
                     /locus_tag="VWX48_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU9170976.1"
                     /translation="MNIKSASDLLEISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQIQTAL
                     NRLNLKIKLYKEGKF"
     gene            46897..47934
                     /locus_tag="VWX48_000277"
     CDS             46897..47934
                     /locus_tag="VWX48_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9170977.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKVGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(47980..48987)
                     /gene="galR"
                     /locus_tag="VWX48_000278"
     CDS             complement(47980..48987)
                     /gene="galR"
                     /locus_tag="VWX48_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU9170978.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            49152..50330
                     /locus_tag="VWX48_000279"
     CDS             49152..50330
                     /locus_tag="VWX48_000279"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU9170979.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLERDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYKEVVGYAPSFYIAEVAGGTRVFD
                     "
     gene            50349..51830
                     /locus_tag="VWX48_000280"
     CDS             50349..51830
                     /locus_tag="VWX48_000280"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU9170980.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKTL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            51900..52304
                     /locus_tag="VWX48_000281"
     CDS             51900..52304
                     /locus_tag="VWX48_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU9170981.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            52485..53249
                     /locus_tag="VWX48_000282"
     CDS             52485..53249
                     /locus_tag="VWX48_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU9170982.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCDIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            53246..53707
                     /locus_tag="VWX48_000283"
     CDS             53246..53707
                     /locus_tag="VWX48_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU9170983.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(53757..55019)
                     /locus_tag="VWX48_000284"
     CDS             complement(53757..55019)
                     /locus_tag="VWX48_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU9170984.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKIANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(55019..55600)
                     /locus_tag="VWX48_000285"
     CDS             complement(55019..55600)
                     /locus_tag="VWX48_000285"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU9170985.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     regulatory      complement(55951..56046)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(56429..56557)
                     /locus_tag="VWX48_000286"
     CDS             complement(56429..56557)
                     /locus_tag="VWX48_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEU9170986.1"
                     /translation="MKANYPIYRLLTKRKFRVSDPYIYPHKFAVLDPNGYFLRFSE"
     gene            complement(56564..56815)
                     /locus_tag="VWX48_000287"
     CDS             complement(56564..56815)
                     /locus_tag="VWX48_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9170987.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLSL
                     EECQLMLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLY"
     gene            complement(56827..57654)
                     /gene="xth"
                     /locus_tag="VWX48_000288"
     CDS             complement(56827..57654)
                     /gene="xth"
                     /locus_tag="VWX48_000288"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU9170988.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHLEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            57788..58244
                     /locus_tag="VWX48_000289"
                     /pseudo
     CDS             57788..58244
                     /locus_tag="VWX48_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            58241..58693
                     /locus_tag="VWX48_000290"
     CDS             58241..58693
                     /locus_tag="VWX48_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU9170989.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            58899..60644
                     /locus_tag="VWX48_000291"
     CDS             58899..60644
                     /locus_tag="VWX48_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9170990.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            60634..62385
                     /locus_tag="VWX48_000292"
     CDS             60634..62385
                     /locus_tag="VWX48_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9170991.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            62558..63250
                     /locus_tag="VWX48_000293"
     CDS             62558..63250
                     /locus_tag="VWX48_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU9170992.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            63293..64519
                     /locus_tag="VWX48_000294"
     CDS             63293..64519
                     /locus_tag="VWX48_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU9170993.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            65649..67808
                     /gene="pfbA"
                     /locus_tag="VWX48_000295"
     CDS             65649..67808
                     /gene="pfbA"
                     /locus_tag="VWX48_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU9170994.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGYGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            67792..68088
                     /locus_tag="VWX48_000296"
     CDS             67792..68088
                     /locus_tag="VWX48_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9170995.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
BASE COUNT        19885 a        12586 c        15206 g        20425 t
ORIGIN      
        1 aattgaatag atattcaatt ttgagtaggt attactcaga gttaagtgac gatagcctag
       61 gagatacacc tgtacccatg ccgaacacag aagttaagcc ctagaacgcc ggaagtagtt
      121 gggggttgcc ccctgtgaga tagggaagtc gcttagctct agggagttta gctcagctgg
      181 gagagcatct gccttacaag cagagggtca gcggttcgat cccgttaact cccaaaggtc
      241 ccgtagtgta gcggttatca cgtcgccctg tcacggcgaa gatcgcgggt tcgattcccg
      301 tcgggaccgt ttaaggtaac gcaagttatt ttagactcgt tagctcagtt ggtagagcaa
      361 ttgactttta atcaatgggt cactggttcg agcccagtac gggtcatata tgcgggtttg
      421 gcggaattgg cagacgcacc agatttagga tctggcgctt aacggcgtgg gggttcaagt
      481 cccttaaccc gcattaagat ataacaaatg agccggctta gctcagttgg tagagcatct
      541 gatttgtaat cagagggtcg cgtgttcaag tcatgtagcc ggcattttta gatagaagaa
      601 aacagtgcga acgtagttca gtggtagaac accaccttgc caaggtgggg gtcgcgggtt
      661 cgaatcccgt cgttcgctta gagaggccgg ggtggcggaa ctggcagacg cacaggactt
      721 aaaatcctgc gattggtaac gatcgtaccg gttcgattcc ggtcctcggc ataatatgga
      781 gcacccttag ctcaactgga tagagtacct gactacgaat caggcggtta gaggttcgac
      841 tcctctaggg tgcatttttc tatttaactc gggaagtagc tcagcttggt agagtacttg
      901 gtttgggacc aaggtgtcgc aggttcgaat cctgtcttcc cgattcatgg cggtgtagct
      961 cagctggcta gagcgtccgg ttcatacccg ggaggtcggg ggttcgatcc ccttcgccgc
     1021 tataatgatc ttgtcggacc tttagctcag ctggttagag ctctcggctc ataaccgagt
     1081 ggtcgtaggt tcaagtccta caaggtccat ttgaatattg gaggattacc caagtccggc
     1141 tgaagggaac ggtcttgaaa accgtcaggc gtgtaaaaac gtgcgtgggt tcgaatccca
     1201 catcctcctt ttatattatt aacgcgggat ggagcagctc ggtagctcgt cgggctcata
     1261 acccgaaggt cgtaggttca aatcctgctc ccgcaataag gctcggtagc tcagttggta
     1321 gagcaatgga ttgaagctcc atgtgtcggc ggttcgattc cgtctcgcgc cattttattg
     1381 atagtattta tgcgggtgta gtttagtggt aaaactacag ccttccaagc tgttgtcgcg
     1441 agttcgattc tcgtcacccg ctttgaactt tgttcaaatt accaagtttt ttaacttggg
     1501 cgcgtagctc aggtggttag agcgcacgcc tgataagcgt gaggtcggtg gttcgagtcc
     1561 actcgtgccc attaattgga gaattactca agaggctgaa gaggacggtt tgctaaatcg
     1621 ttaggtcggg taactggcgc aagggttcga atcccttatt ctccgtttta atgagagttt
     1681 gtaactctct tttttatttt tagagacaat aaagcttcag atccgtaaaa cttaattgaa
     1741 ttactaatct gaagttattt ttatggctct ttgtcaactg tagtgggttg aagaaaagct
     1801 aagctcgaga aaggacaaat ttcgtccttt cttttttgat gttcaaagcg ataaaaatcc
     1861 gttttttaaa gttttcaaag tttcgaaaac caaaggcatt gcacttgata agtttgatga
     1921 gattattggt cgcttccagt ttggcgttag aatagtgtag ttgaagggcg ttgacaatct
     1981 tttctttatc tttgaggaag gttttaaaga cagtctgaaa aataggatga acctgcttaa
     2041 gattgtcctc aataagtccg aaaaatttct ctggttcctt tttcttcatt agacttccac
     2101 aatcagggca agatggagcc tcataatcca gcttagcgat aatttctttg tgggtatcca
     2161 tattgatgat atctagaatc ttgatgtttg ggtctttaat atcgagcagt tttgtgataa
     2221 aatgtaattg ttccatatga atctttctaa tgatggtttt gtcgcttttc attataggtc
     2281 atatgggact ttttttctac aacaaaatag gctccataat atctataagg gatttaccca
     2341 ctacaaatat tatagagcca ataaaacttc agatccgtaa aacttaattg aattactaat
     2401 ctgaagttat ttttatatcg tttatattat aattgtgtta ttttacttcc aactattgag
     2461 agaaatttcg ccactattta gccagatttc ttttccgtta tcacattgaa ctaaaagttt
     2521 tccattttct gagatgtctt tagcaagtcc cttgtagtct ttttgctcta gtgtgaaagt
     2581 gacttctttt cctagaatga atgactgttt tttgtatagg tataatagct cttctgctgg
     2641 tgtttcgaag aaagcacgcc agatttctat gatcaattca ttccttgtta taggagctgt
     2701 agctttaaat aagctggcag ctttttcttt taattcctga gggaagtctt taatagtgaa
     2761 attgatacct actccaataa tgatatctgt gactaagcca gtttctacag aggtcattgc
     2821 ttcagtaagg attcctccaa ttttatgatt gtttagatag atatcattga cccattttat
     2881 gtcgacatct attaaagtta ggttcttaat ggctttgtag acagctccag ctacaagtag
     2941 tgtgtaggat ggtaatttgt cataggggag atttggttta agatggagtg tcatataaat
     3001 accaccttgt ggtgagtaga aggaacgttg aaaacggcct cggcctgctg tttgatagga
     3061 agctagatag agggtatttg cttcatggcc taaatcaatt gcttcttttg catctagttg
     3121 tgttgatttt gtttcgggtt taaagctgac tttaattgga agattttctt ctagaatctc
     3181 tggaagaata aggtcaccat tcatcagttt gtatcctcta tttttgatac tatcaatttc
     3241 aatgccttct tgttctagtc gcttgatagc tttccaaatt gatgttcggc ttagggatag
     3301 tttttctgcg attttttctc cgctgatata gtcggtttct ttagatagga tttggtagac
     3361 agcttggtag gatttcataa tgttgccttt ctcactagtt ggtattgaga gtattctttt
     3421 cttgtatgac ttggagtctg attaaagtat tgtttataag ctttcgaaaa atggagtgga
     3481 tctgaaaaaa ctaccgagta tgcaattacc ttgatggact cttgggtatt ttcgagaagt
     3541 tgtctagctc ggtgcattcg aacgtagagt aggtattctt tgggtgataa ggtattaaat
     3601 tctttgaata cgcttgataa gtagcttctg tgaacggata gttcttttgc taaatcttga
     3661 attgtaagtg attgaggata gtggctatca attaatcgtt tgcattcaag atagagttgg
     3721 tgggttgatg aaatattctt ttttttctga ttgggagcaa tagttcccag atgaaacatc
     3781 agttcatgaa gttgtcccat gatatggagt tgagctaatt cacttgattt tgtaatctga
     3841 gcgaagcgga caatgtctga gatgagtttt gcagtagtct gggtatgaca agtttcagat
     3901 tggatgagat aggattgatc agaaatttga gaaagagcaa aataatcagg ggatttccct
     3961 ccagtgattc ctaaccagta gtaggcccaa ggttctttac tatctgcttg ataaaaggtt
     4021 agttcctctg gttttaatag aaagaaatct ccttctttta aatcaacaat tttacccttg
     4081 taatgaaatt ttccttgtcc tttagtaatg taatgtagga cgtatgtatc acgaatggct
     4141 ggaccaaaag agtaattagg tgtgcattcc tcatatccat aaaagcttag ggcaaggtcg
     4201 attgttccag tctggtattc tgaaaaaact aacatgtgct acctcctacc taacatttta
     4261 ccatattctt gagacatttt tctattttag aaagcgattt caggtgataa aatataatca
     4321 ataaagtgat gaggtgaagt aaatgggagt taggatagag aataatctat tttatgttga
     4381 gagtaaaaat ctaagtttga ttattgaaaa tcgaaatggc tacttacttt tgaaacattt
     4441 aggaaagact attaagaact ataaaggttc caatagtgtt tatgaacgag accatgcctt
     4501 ttcaggaaat ccaacagcta ctaatcgaac ctttagttta gatactcaac gtcaaatttt
     4561 tggacaacat ggcttaggag attttaggaa accaaccata caggttcagc ataatgtaac
     4621 tgaagtaaca gactttcgat ttgtagaagc aaagatttta aaaggtcaga atggtccaca
     4681 gggcttacct tctccacata gcatggacga tacagagact cttgtcttaa tgttagaaga
     4741 ttctaaggct caacttagtc tgactttgta ttatactact tttaataatg atgcgactat
     4801 tgctagctac agtaaattag ataataatag taatcaggaa gttgtcatct ataaagattt
     4861 ttcttttatg gctgattttc cagctgcaga ttacgaaata gtaactctgc agggtgctta
     4921 tgctcgtgaa aagactgtta gacgtcaaca ggtagaacaa ggaatctttt cgattagttc
     4981 aaaccgaggt gcttctggtc atgctcaaac accagctctt ctactatgcg aacaaggagt
     5041 cacagaggat gctgggaatg tgtttgctat tcaactaatg tatagtggca actttgaagc
     5101 ttttgttcaa aaaaatcaat tgaatgaagt tcgggtggct attggcatta atccagaaaa
     5161 cttttcttgg aagttagccc ctgaggaata ctttgaaaca ccggtagctt tagtgactca
     5221 ttcagatcag ggattaactg gtattagtca tgaaagtcag aattttgtac tgaagcacat
     5281 tatgctaagt gaattttcta aaaaagaacg tccaattcta atcaataact gggaagctac
     5341 ttactttgac tttcagagag aaaaactgtt agagttagca gatgaagcta agaaagttgg
     5401 cattgaactt tttgtattag atgatggttg gtttggcaat cgttttgatg ataatcgtgc
     5461 tttaggtgat tgggttgtta atgaggaaaa actgggtgga agtctagaaa gtctgatttc
     5521 agctatccat gaaagaggtt tgcagtttgg actttggtta gaacccgaaa tgatttctgt
     5581 agatagtgat ttgtatcgtc aacatcctga ctgggctatt caggttcctg gctatgagca
     5641 tacttattct cggaatcaat tagtacttaa tcttgccaat cctcaggtag tagaatactt
     5701 gaaaagtgtc ttagatcaac tcctatctta tcatgatatt gattacatta aatgggatat
     5761 gaaccgcaat atcactaagc tagggaatgg attaacttat ctagagacac agatgcaatc
     5821 tcatcagtac atgctggggc tttacgaact cgtttcttat ctgacagaga agcacagcca
     5881 tattctcttt gagtcctgct ctggtggtgg tggacgaaat gatcttggta tgatgcgcta
     5941 tttcccacaa gtctgggcta gtgataatac tgatgccatt gcacgtttac caattcaata
     6001 cggttcatcc tatctctatc caaccatttc tatgggggct catgtgtcag cagtaccgaa
     6061 tcatcagatg ggacgaatga caccattaga aacacgtggc cttgtagcaa tgatgggaaa
     6121 tttgggctat gaacttgatt tgacaaattt atcagatgaa gagaaagcta cgattgctaa
     6181 tcaggtgaac ttgtataaag aattacgacc agtagttcag ttaggacagc agtatagact
     6241 aattaatcct gatactgtat ccaatgaagc agctgtacaa tttaattacg gaaatcaaac
     6301 gattgtaacc tacgttcgcg ttttatctgt tgtagagacc atggaaacaa ctttaaaatt
     6361 aaaagatttg gatgaagagg gactatataa attacaggaa aatggcgaag tttactcagg
     6421 tgcagaacta atgtatgcgg gcctaactgt tatcttatcc caaggagatt ttttgagtag
     6481 acagtatatt tttagaagac tatgataagg gtgtataaat ttataaagga ggctttctaa
     6541 tggaatggta taaaaaaatc ggacttcttg caactacagg tttagctttg gttgggcttg
     6601 gcgtttgctc caactatggt aaatctgcgg atggcacagt gaccatcgag tatttcaacc
     6661 agaaaaaaga aatgaccaaa accttggaag aaatcactcg tgattttgag aaggaaaacc
     6721 ctaagatcaa ggtcaaagtc gtcaatgtac caaatgctgg tgaagtattg aagacacgcg
     6781 ttctcgcagg agatgtgcct gatgtggtca atatttaccc acagtccatc gaactgcaag
     6841 aatgggcaaa agcaggtgtc tttgaagatt tgagcaacaa agactacctg aaacgcgtga
     6901 aaaatggcta cgctgaaaaa tatgctgtaa acgaaaaagt ttacaacgtt ccttttacag
     6961 ctaatgctta tggaatttac tacaacaaag ataaattcga agaactgggc ttgaaggttc
     7021 ctgaaacctg ggatgaattt gaacagttag tcaaagatat cgttgctaaa gaacaaacac
     7081 catttggaat tgcaggtgca gatgcttgga cactcaatgg ttacaatcaa ttagcctttg
     7141 cgacagcaac aggtggagga aaagaagcaa atcaatacct tcgttattct caaccaaatg
     7201 ccattaaatt gtcggatccg attatgaaag atgatatcaa ggtcatggac atccttcgca
     7261 tcaatggctc taagcaaaag aactgggaag gtgctggcta taccgatgtt atcggagcct
     7321 tcgcacgtgg ggatgtcctc atgacaccaa atgggtcttg ggcgatcaca gcgattaatg
     7381 aacaaaaacc gaactttaag attgggacct tcatgattcc aggaaaagaa aaaggacaaa
     7441 gcttaaccgt tggtgcggga gacttggcat ggtctatctc agccaccacc aaacatccaa
     7501 aagaagccaa tgcctttgtg gaatatatga cccgtccaga agtcatgcaa aaatactacg
     7561 atgtggacgg atctccaaca gcgatcgaag gggtcaaaca agcaggagaa gattcaccgc
     7621 ttgctggtat gaccgaatat gcctttacgg atcgtcactt ggtctggttg caacaatact
     7681 ggaccagtga agcagacttc cataccttga ccatgaacta tgtcttgacc ggtgataaac
     7741 aaggcatggt caatgattta aatgccttct ttaacccgat gaaagcggat gtggattagg
     7801 agtagagaga ctatgaaaaa agtattacaa aaatattggg catgggcttt tgtggtcatc
     7861 cccctcttgt tacaagcaat tttcttctat gtgccgatgt ttcaaggagc cttttacagt
     7921 tttaccaact ggacaggatt gacttataac tacaaatttg tcggcttaaa caactttaag
     7981 ctcctcttca tggattcaaa attcatgaat gcgattggct ttaccgcaat cattacgatt
     8041 gccatggtgg ttggtgagat tgcactcggg atcttcattg cgcgtgtctt gaactctaaa
     8101 atcaaaggcc aaaccttctt ccgtgcttgg ttcttcttcc cagctgtttt atctggtttg
     8161 acagtggctt tgatcttcaa gcaagtcttc aactacggtc ttccagcgat tgggaatgcc
     8221 cttcatattg aatttctcca aaccagtctt ttagggacta agtggggagc aatctttgcg
     8281 gctgcctttg tccttggttg gcaaggggtg gctatgccca tcatcatctt cctagctggt
     8341 ttgcaatcta ttccaactga gattacagag gcagcaagga ttgatggtgc gactagcaag
     8401 caagttttct ggaacattga attgccttac ttgctaccaa gtgtctctat ggtctttatc
     8461 ctagccctaa aaggtgggct gactgccttt gaccaagtct ttgccatgac cggtggtggt
     8521 ccaaacaatg ccacaacctc acttgggctc ttggtttata actatgcctt taaaaacaac
     8581 caattcggtt atgccaatgc cattgccgta atcttgttcc tcttaattgt agtgatttcg
     8641 atcatccaat tgagagtatc taagaaattt gaaatttaag aggagaagca tgatgaaaca
     8701 agatgaaaga aaagccctga ttggcaaata cattctattg attctaggat cggttctgat
     8761 tttagtgccg ctccttgcta ccctctttag ttcctttaaa cccactaagg atattgtaga
     8821 taatttcttt ggctttccaa ccaacttcac atgggacaac tttagccgtc tcttagctga
     8881 tgggattgga ggctattatt ggaactctgt cgtcatcact gtcttgtctt tacttgcagt
     8941 aatgatcttt atccctatgg cagcctactc catcgctcgc aatatgagta aaagaaaagc
     9001 ctttaccatc atgtataccc tcttaatcct cggaatcttc gtacctttcc aagtcatcat
     9061 gattccgatt acggttatga tgagtaaact cggtttggct aatacctttg gtttgatctt
     9121 gctctacttg acctatgcga ttccacagac cctctttctc tatgttggct atatcaaaat
     9181 ctcgattcca gaaagtctgg atgaagcagc agagatcgat ggggctaatc aatttacaac
     9241 ctatttccgc atcatcttcc caatgatgaa accgatgcat gcgacaacca tgatcatcaa
     9301 tgccctttgg ttctggaatg acttcatgtt gccactcctt gtcttgaacc gggattccaa
     9361 aatgtggact ctgcctttgt tccaatacaa ctacgcaggc caatatttca acgactacgg
     9421 accaagcttt gcctcttacg tggtcggcat tatcagtatc accattgtct atctcttctt
     9481 ccaacgccat atcatttcag gaatgagcaa cggggcagtg aagtaatact caatgaaaat
     9541 caaagagcaa actaggaagc tagccgcagg ctgtacttga gtacggtaag gcgacgctga
     9601 cgtggtttga agagattttc gaagagtata agaagagctc atggaatcta tagtctttga
     9661 cacagaggaa gagttcagct tgttgataat tctatgtaga aaacaagaaa gtagtacttt
     9721 gtttatcaca gtctatatta gtacgagttt gatgataaat agagatttaa aatgaatttg
     9781 atttacgaag ccagatcata tgagacttgg cttcaattag aaaaaggaga gtaatgatgc
     9841 caattcaaaa taaaaccatg ttgattacct attctgatag ccttggaaat aatcttaaag
     9901 acttatatga taatttggaa gagcattttg gagatgctat tggaggagtt caccttttac
     9961 catttttccc atcaacaggt gatcgtggat ttgcgccagt tgactacgac gaagtggact
    10021 cagcttttgg tgattgggag gatgttaagc gtttaggtga gaaatattat cttatgtttg
    10081 attttatgat taatcatatt tctcgtcaat ccaagtatta taaggactat caagaaaaac
    10141 atgaagccag tgaatttaaa gatctctttt taaactggga taagttttag ccagaaaacc
    10201 gtccgacaca gtctgatgta gatttaattt acaagcgtaa ggatcgtgca ccaaagcaag
    10261 agattgtgtt tgaagatggt tcagtggaac atttgtggaa tacctttggt gaggagcaga
    10321 ttgatcttga tgtgaccaaa gaagtaacta tggaatttat ccgtaagacc attcagcact
    10381 tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt tgcttatgca gtgaagaaat
    10441 tggatactaa tgatttcttt gtggaaccag atatttggga tttattggac aaagttcgag
    10501 atatcgctgc tgagtatggg acagagcttt tacctgagat tcatgaacac tattcgattc
    10561 agtttaaaat agcagaccat gattactatg tttatgattt tgctcttcca atggtgacac
    10621 tttatactct ttacagttcc agaacagagc gtttggctaa gtggttaaag atgagcccga
    10681 tgaagcaatt tacgacgcta gatacccatg atgggattgg agtagtagat gtcaaggata
    10741 tcctgaccga tgaggagatt gactatgctt caaatgaact ctataaggtt ggagccaatg
    10801 tcaaacgtaa gtactctagt gccgagtata acaacttaga tatctaccaa atcaattcaa
    10861 cctactattc agcgcttgga gatgatgatg tcaagtattt tctcgctcgt ctaattcaag
    10921 cttttgcccc aggtattcct caggtttact atgtgggtct attagcaggc aagaatgact
    10981 tgaaattatt agaagaaact aaagaaggtc gaaatattaa tcgtcattac tatagcaacg
    11041 aggaaatagc aaaagaagtg caacgacctg ttgtgaaggc ccttctcaat ctattttctt
    11101 tccgtaaccg ttcagaagcc tttgatctag aagggactac tgagatagag acaccaacag
    11161 ctcacagcat tgtaatcaaa cgtcaaaata aagataagtc cgtaacagca gtagcagaaa
    11221 ttgatttgca aaatcagact tatcgggtaa ttgagaatgg agttgaagta acattttgaa
    11281 gccttgatat ggtggataaa atagggtttt tattttggaa aacgtttcct ttgttttcaa
    11341 attgctaaaa aagtggtaca atataggata gcttactatt atctgaatca gctgatttgg
    11401 agagaaagga ttcattttga aatcaatagg ctttattgaa aagctgaagg ggttgtctag
    11461 taaagagctg attttattgg gaattatcct aagtatcttt ttaccctttt atctttttgt
    11521 agttgtactc tgtttatata ttatcagttt gatttttaca ggagacatga aaagtattct
    11581 tcagaaaatg ggggagcatc cgatgctgct tctttttctt agctatagta ctgttatatc
    11641 cattcttgca caaaattgga tgggtcttgt ggcttcagta ggaatgtttc tatttactat
    11701 tttctttttg cactatcagt cgattttatc ccataaattc tttcgattga ttttgcagtt
    11761 cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt ttagaacatt tccaaattgt
    11821 gaagaaattt aactatgctt ttctttcacc caatatgcag gtgtggcatc agaaccgggc
    11881 agaagtgacc ttctttaatc ctaattatta tggaattatt tgttgtttct gtattatgat
    11941 tgctttctat ctgtttacaa cgaccaagtt gaattggttg aaagtattct gtgtgattgc
    12001 aggctttgtt aatctctttg gtttgaactt tactcaaaat cgaactgcct ttcctgctat
    12061 tatcgctgga gcaattatct atctctttac gactattaaa aactggaagg ccttttggct
    12121 tagtattggg gtcttcgcga ttggtttgag tttcctcttt tctagtgatt tgggagttcg
    12181 aatgggtact ttagactctt ctatggaaga acgcatttct atctgggatg ctgggatggc
    12241 cttgtttaag caaaatcctt tttggggtga agggccattg acctatatgc actcttatcc
    12301 tcggatacat gctccttatc atgaacatgc ccacagtctt tatattgata cgattctgag
    12361 ttacggaatt gtgggtacca ttttattagt tttgtcttct gttgctcctg ttcgcttgat
    12421 gatggatatg agtcaggagt cggggaaacg tccgattatc ggcctttatc tatctttcct
    12481 tacagtggtt gctgtgcacg gaatttttga cttggctctc ttctggattc agtcaggctt
    12541 tattttcttg ctagttatgt gcagtattcc attggagcat cgaatgttgg tatcggacat
    12601 gacggattaa gttttataag tttgaaatct tctaccttgg gtaggagatt tttttatacg
    12661 atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg gatccactac cggtgaatac
    12721 aatagcgctc cccaagcctg actatcgtga ggtagcggat taaaatggtc tggggataga
    12781 tcgttttaag tctgacgcag gaaataagaa ttgtcagaga aagcaatagt gaaatcgtag
    12841 gctatgaata gaaacgtgat agcgaggagc atatagtgga taaggtagcg agaaatttta
    12901 aagtataaaa gatagtctta atctatatat gtaaatcaca aaagtaattg aattcggaat
    12961 aaggttggtg tgaaaagaca tagtaaactg aatcttgaat actagaatga tacttctaca
    13021 atattgttat aatttaattt gaattccaaa atcacattgt tccgtccgta tttcatttta
    13081 ctgtatgtct tcctaaactc caaagtttct gcgtcaaatt tcctattttc actgtagtct
    13141 ttgacacttc gaacgacaat ttgaatcata tattcaaaaa aaaaatgaaa aatttgtgcc
    13201 aacaagccta aatattctga aaatttgttt gatttttaat ggataatgtg atataatggt
    13261 tgtcaatcta taattcacat aaacagagga gtagaaaatg aaaaaaaatc gtgtatttgc
    13321 tacagcaggt cttgttttat tagcagcagg tgtacttgca gcatgcagtt cttcaaaatc
    13381 atctgattca tcagccccta aagcttatgg ctatgtttat acagcagacc cagaaacctt
    13441 ggactacctg atttcaagta aaaatagtac aacagtagtg acttcaaatg ggattgatgg
    13501 tttattcact aacgataatt acggtaatct tgctcctgca gttgcagagg attgggaagt
    13561 ctctaaggat ggtttgacct acacttataa gattcgtaaa ggggttaaat ggtttacctc
    13621 tgatggagaa gaatatgcag aggtgacggc taaagatttc gtgaacggtt taaaacacgc
    13681 agcagataaa aaatcagaag ctatgtattt agctgaaaat tcggttaaag gcttggcaga
    13741 ttatctatca ggaacttcaa cagatttttc aacagttggt gtcaaggcgg ttgatgatta
    13801 tacgttacaa tacactttga accagcctga accgttctgg aactctaagt tgacctattc
    13861 tattttctgg cctctgaatg aagaattcga aacatcaaaa ggaagcgatt ttgctaaacc
    13921 aacagatccg acatccttgc tttataatgg tccattcttg ttgaaagggt tgactgcaaa
    13981 atcttctgta gagtttgtaa aaaatgagca atattgggat aaagaaaatg tccacctaga
    14041 tactatcaat ctagcttact atgatggatc agatcaggag tcgctagagc gtaacttcac
    14101 tagtggagct tatagttatg cccgtcttta ccctaccagc tccaactatt ctaaggttgc
    14161 agaagaatac aaggacaata tctattacac acaatcaggc tctgggattg ctggtctggg
    14221 tgtgaatatt gatcgccaaa gttacaacta tacttctaaa actacagatt cagagaaagt
    14281 agctactaag aaggcattgc ttaacaaaga tttccgtcaa gccttgaatt ttgctcttga
    14341 tcgctcagct tactcagctc aaatcaatgg taaagatgga gcagctttag cagttcgtaa
    14401 tttatttgta aaaccagact ttgtttcagc tggtgagaag acctttggtg atttagtcgc
    14461 tgctcaactt cctgcttatg gtgatgagtg gaaaggtgtg aatttagctg atgggcagga
    14521 tggtttattc aatgctgaca aggccaaggc agagtttgcg aaagctaaga aagctttaga
    14581 agcagacggc gttcagtttc ctattcatct ggacgttcca gtagaccaag catcaaaaaa
    14641 ctacatatct cgtattcagt cttttaaaca atctgtagaa acagttcttg gtgttgaaaa
    14701 tgtcgttgtt gatattcaac aaatgacaag tgatgaattc cttaatatta cttactatgc
    14761 tgccaatgct tcatctgagg attgggatgt atcaggagga gtttcatggg gtccagacta
    14821 tcaagaccca tctacttacc tggatatttt aaaaacaaat agcagtgaaa ctacaaaaac
    14881 atatttagga tttgataatc caaatagccc ttcagtagtt caagttggtt tgaaagaata
    14941 cgataaatta gttgatgaag ctgccagaga gacaagcgac ttgaatgtcc gttatgaaaa
    15001 atatgcagcg gctcaagcat ggttgacaga tagttcactc tttattcctg ctatggcttc
    15061 ttctggtgca gcaccagtgc tttcacgaat tgttccattt actggagctt ctgcgcaaac
    15121 aggctctaag gggtcagatg tttacttcaa atatttgaaa ttacaagata aagtggtgac
    15181 taaggaagag tatgaaaaag ctcgtgaaaa atggttgaaa gaaaaagctg aatcaaatga
    15241 gaaagctcaa aaagaattgg caagtcatgt gaagtaaata atttctaata gaactttctc
    15301 tccatgagga gaaggttctt ttgggatttt taaaggaaat aatatgaaaa aatatatttt
    15361 tatgcgtgtt ttgcggtcat tggtttcgat tttcttagta acgactttga cctacacgat
    15421 tatctatacc ttggttcctc gaaaattgat tttcaagcag gatcctaact ataataaaat
    15481 tgcgacaacg gctgataaac gtgataacta tgaaaatact gtgtttgagc gtatgggcta
    15541 cattgagtat tacgatacta aagagttgca agaaaaggca agtagcatgg attcttctgt
    15601 aacagtagaa gcaaatgcga ccaataaagc tatttatgaa aagtacatca atcaattagg
    15661 tcatggttgg actttgggag aatttactga aagtggtcaa ttctatgcta ctcgtgaaat
    15721 tccaattttt gaacgtgttt ttcacttcta tgctaacttg attgacattg accatacaaa
    15781 taaaatccaa gaccctgaaa atccagactt gaaacgctac cttcgttttg aaaatgatcc
    15841 agctatcgga tggtcattgg tcggttcagg aactaaacat aaatatctct tgtactttaa
    15901 cagtcagttc ccatttgttc atcaaaactt tgtgaacttg aatttaggtg actcttaccc
    15961 aacctatgct aatacaccag ttcttcaggt tattactcaa ggtcaaggac aaaccaaaac
    16021 tgcccaagtt cagttcccaa caggtaagaa aacgtcttct gtaaatattt actcaagaac
    16081 ctacaagtca cctagtcagg ctgactctcg tgaagtagct agctatggga aagatgatcc
    16141 ttatacagcg actgaaagta attaccaata tccatctatg attgtcagct ctgctattac
    16201 tggtttgatt ggtttggttc ttgcctatgc tcttgccgtg ccacttggtt cagccatggc
    16261 tcgtttcaag aacacttgga ttgatagcct ctcaacaggg actttgacct tcttgcttgc
    16321 tcttccaacg attgccttgg tttacatcgt tcgattgatt ggatcatcta ttgcccttcc
    16381 agattcattc cctatcttgg gagctggaga ttggcgttct tacgttttac cagcagtcat
    16441 ccttggtttg ttgggtgctc ctgttacagc catttggatt cgtcgttaca tgattgactt
    16501 gcaatctcaa gactttgttc gtttcgctcg tgcaaaaggt ttgtctgaaa aagaaatttc
    16561 aaacaaacac atctttaaaa atgccatggt tccgctggtt tcaggaattc ctggtgccat
    16621 tattggggtt atcggtggtg caacccttac tgaaacagtc ttcgccttcc caggtatggg
    16681 taaaatgttg attgactctg taaaagcatc taataactct atggtcgttg gtcttgtctt
    16741 catctttaca tgtatttcta tcttctcacg tcttttggga gatatttgga tgactattat
    16801 tgacccacgt attaaattga ctgagaaagg aggcaaataa tgtctacaat cgataaagaa
    16861 aaatttcagt ttgtaaaacg tgacgatttt gcctctgaaa ctattgatgc gccagcatat
    16921 tcttactgga aatcagtgtt taaacaattt atgaagaaaa aatcaactgt agtcatgttg
    16981 ggaatcttgg tagccatcat tttgataagt ttcatctacc caatgttttc taagtttgat
    17041 ttcaatgatg tcagcaaggt aaacgacttt agtgttcgtt atatcaagcc aaatgcggag
    17101 cattggttcg gtactgacag taacggtaaa tcgctctttg acggtgtctg gttcggagct
    17161 cgtaactcca tcctcatttc tgtgattgcg acagtgatta acttggttat cggtgttttt
    17221 gtcggtggta tttggggtat ttcaaaatca gttgaccgtg tcatgatgga agtttacaac
    17281 gtcatctcaa acatcccacc tcttttgatt gttattgtct tgacttactc aatcggagct
    17341 ggattctgga atctgatttt tgccatgagc gtaacaacat ggattggtat tgccttcatg
    17401 atccgtgtgc aaatcttgcg ctatcgtgac ttggaataca acttggcgtc acgtactttg
    17461 ggaacaccaa ccttgaagat tgttgtcaaa aatatcatgc ctcaattggt atctgttatt
    17521 gtgacaacca tgactcaaat gcttccaagc tttatctcat acgaagcctt cttgtctttc
    17581 ttcggtcttg gattaccgat tacagtgcca agtttgggtc gtttgatttc ggattattca
    17641 caaaacgtaa caaccaatgc ttacttgttc tggattccat tgacaaccct tgtcttggta
    17701 tccttgtccc ttttcgtagt tggtcaaaac ttagcggatg ctagtgatcc acgtacacat
    17761 agataggagt agaaatgaca aaagaaaaaa atgtaatttt gactgctcgc gatattgtcg
    17821 tggaatttga cgttcgtgac aaagtattga cagccattcg cggcgtttct cttgaactag
    17881 ttgaaggaga agtattagcc ttggtaggtg agtcaggatc aggtaaatct gttttgacaa
    17941 agaccttcac aggtatgctc gaagaaaatg gtcgtattgc ccaaggtagt attgactacc
    18001 gtggtcagga cttgacagct ttatcttctc acaaggattg ggaacaaatt cgtggtgcta
    18061 agattgcgac tatcttccag gacccaatga ctagtttgga ccccattaaa acaattggta
    18121 gtcagattac agaagttatt gtaaaacacc aaggaaaaac agctaaagaa gcgaaagaat
    18181 tggccattga ctacatgaat aaggttggca ttccagacgc agatagacgt tttaatgaat
    18241 acccattcca atattctgga ggaatgcgtc aacgtatcgt tattgctatt gcccttgcct
    18301 gccgacctga tgtcttgatc tgtgatgagc caacaactgc cttggatgta actattcaag
    18361 ctcagattat tgatttgcta aaatctttac aaaacgagta tcatttcaca acaatcttta
    18421 ttacccacga ccttggtgtg gtggcaagta ttgcggataa ggtagcggtt atgtatgcag
    18481 gagaaatcgt tgagtatgga acggttgagg aagtcttcta tgaccctcgc catccatata
    18541 catggagtct cttgtctagc ttgcctcagc ttgctgatga taaaggggat ctttactcaa
    18601 tcccaggaac acctccgtca ctttatactg acctgaaagg ggatgctttt gccttgcgtt
    18661 ctgactacgc aatgcagatt gacttcgaac aaaaagctcc tcaattctca gtatcagaga
    18721 cacattgggc taaaacttgg cttcttcatg aggatgctcc aaaagtagaa aaaccagctg
    18781 tgattgcaaa tctccatgat aagattcgtg aaaaaatggg atttgcccat ctggctgact
    18841 aggaggaagg aaatgtctga aaaattagta gaaatcaaag atttagaaat ttccttcggt
    18901 gaaggaagta agaagtttgt cgcggttaaa aatgctaact tctttatcaa caagggagaa
    18961 actttctcgc ttgtaggtga gtccggtagt gggaaaacaa ctattggtcg tgctatcatc
    19021 ggtctaaatg atacaagtaa tggagatatc atttttgatg gtcaaaagat taatggtaag
    19081 aaatcgcgtg aacaagctgc ggaattgatt cgtcgaatcc agatgatttt ccaagaccct
    19141 gccgcaagtt tgaatgaacg tgcgactgtt gattatatta tttctgaagg tctttacaat
    19201 caccgtttat ttaaggatga agaagaacgt aaagagaaag ttcaaagtat tatccgtgaa
    19261 gtaggtcttc ttgctgagca cttgactcgt taccctcatg aattctcagg cggtcaacgt
    19321 caacgtatcg gtattgcccg tgccttggtc atgcaaccag actttgttat tgcagatgag
    19381 ccaatttcag ccttggacgt ttctgtacgt gcccaagtct tgaacttgct caaaaaattc
    19441 caaaaagagc tcggcttgac ctatctcttc atcgcccatg acttgtcggt tgttcgcttt
    19501 atttcagatc gtatcgcagt tatttacaag ggtgttattg tagaggttgc agaaacagaa
    19561 gaattgttta acaatccaat tcacccatat actcaagcct tgctttcagc agtaccaatc
    19621 ccagatccaa tcttggaacg taagaaggtc ttgaaggttt acgacccaag tcaacacgac
    19681 tatgagactg ataagccatc tatggtagaa atccgtccag gtcactatgt ttgggcgaac
    19741 caagccgaat tggcacgtta tcaaaaagga ctaaactaat aatggtttta taatttccat
    19801 gtcaattttt atggaaatta ggctctttgt caactgtagt gggttgaagt cagctaagct
    19861 cgagaaagga caaatttcgt cctttctttt ttgatgttca aagcgataaa aatccgtttt
    19921 ttgaagtttt caaagtttcg aaaaccaaag gcattgcgct tgataagttt gatgagatta
    19981 ttggtcgctt ccagtttggc attagaatag tgtagttgaa gggcgttgat aatcttttct
    20041 ttatctttga ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg cttaagattg
    20101 tcctcgataa gttcgaaaaa tttctctggt tccttattct ggaagtgaaa aagcaagagc
    20161 tgatagagct gatagtggtg tttcaagtct tgtgaataac tcaaaagctt gtttaaaatc
    20221 tctttattgg ttaagtgcat acgaaaagta ggacgataaa atcgcttatc actcagttta
    20281 cggctatcct gttgtatgag cttccagtag cgcttgatag ccttgtattc atgggatttt
    20341 cgatgaaact gattcatgat ttggacacgc acacgactca tagcacggct aagatgttgt
    20401 acaatgtgaa agcgatcaag aacgatttta gcattcggga gtgaaacagt ctagaagact
    20461 gtttcagcct gagcctagaa atttgaaagc gaagctgttt agccaagtca tagtaagggc
    20521 taaacatatc catagtaatg attttgacgc gacatcggac ggctctatca tatttaagaa
    20581 agtgatctcg gatgacagct tgtgttctac cttcaagaac agtgatgata tcgagctttt
    20641 caaaatcttg cgcaataaag ctcatctcca tctcccgatt gaaacagtca ctccccggac
    20701 tgtttcaacg tcccaagaca taatcttagg cagatttcta aaattacact caaagtggaa
    20761 gtcattgagc tttcgaatga cagttgaagt tgagatggaa agctgatggg caatatcagt
    20821 catagaaatc ttttcaatta acttttgagc aatcttttgg ttgatgatac gagggatttg
    20881 atgattcttc ttgacgatag aagtttcagc aaccataatt ttagaacaat gatagcactt
    20941 gaaacgacgc tttctaagga gaattctagt aggcatacca gtcgtttcaa gataaggaat
    21001 tttagaaggt ttttgaaagt catatttctt catttgactt ccgcactcag gacaagatgg
    21061 agcttcatag tccagtttgg cgatgatttc cttgtgtgta tccttattga tgatgtctaa
    21121 aatctggata ttagggtctt taatgtctag taattttgtg ataaaatgta attgttccat
    21181 atgaatcttt ctaatgagtt gttttgtcgc ttttcattat aggtcatatg ggactttttt
    21241 tctacacaaa ataggctcca taatatccat aggggggtta cccactacaa atattataga
    21301 gccgaaaaag gctgagatct ggtgtctcag tcttttattt cttgcgtttt gcaaaatcta
    21361 caaatctaaa tttttctaac ttatggcgac tttcggtaaa ctgaaattgg cgtccgtctt
    21421 ggagatagac ttttgattta atcgaaacga cataagggtc tttgccaatg tccatgagaa
    21481 tcttgtctcg gtcgcttgag tggtcaatgg tgatttcctt ctgagcataa tcaataagga
    21541 gtttgaggcc attttctata taagaataga tagactgctc agcaatttgg cgagtgagat
    21601 ttggaattag ttccatatcc agatagtctg tatccagaac ggataccaga tcatccacca
    21661 cacgctggcg gaccaccttc caaaccatcc gaaactctgg gaaaccggtt atcagtgagg
    21721 attttttatc aataataatc ttgtccagac tgaccacgtt ggttttagag cgcagtccaa
    21781 gttctttaac tagttcttgg tagctggtta ggttggatac agggaaattg acggtttctt
    21841 ctttgacgac ttgagaacct tgccctctta tctttttgat caatccttcc tcttggagga
    21901 gagacagggc ctttcggacg gtatcacgac tcacttgata ttgctccata aggtcgtgct
    21961 cgctaggaag gaaatctccg acagcgtaag tctcgttttg aatggtttct tggatttgct
    22021 taaataattg ttggtatttc ttcattttgc ctgcttaaat aggtttttag tctagtttaa
    22081 tgaacacctg tatctatttt accatacaag tgctagaaaa tttacaaaaa aacacccttt
    22141 ttataccaaa caagttgcag acaagtttgg tatcgtttac aatatactta tcaaatcaaa
    22201 cttgctttga caagtataag gagaatcaaa tgggaaaatt tgaacaagaa gccaaagatc
    22261 tgcttcaggc aattggaggc aaagaaaatg tgactgccgt cacccactgt gcgacacgga
    22321 tgcgctttgt tttaggagat gataagaagg ctaatgttaa agctatcgag tcaattccag
    22381 ctgttaaagg aacttttaca aatgcaggtc aatttcaggt aatcattgga aatgacgtgc
    22441 ccatctttta taatgatttt acagccgttt caggtattga gggtgtttcc aaagaagcag
    22501 ccaagtctgc agctaagagt aatcaaaacg tggtccaacg tgttatgacc actctggcgg
    22561 agatttttac tccgattatt ccagccttga tagtcggagg attgatcctc ggtttccgta
    22621 atgtcttgga aggtgtccat tggtcgatgt tggatggcaa gaccatcaca gaatcctctc
    22681 agttttgggc aggtgtcaat cacttcctct ggttgcctgg tgaagctatc ttccagttct
    22741 taccagtagg gattacttgg tctgtttctc gtaagatggg aaccagccaa attttgggaa
    22801 ttgttctcgg aatctgtttg gtatcgcctc agttgctcaa tgcctatgcg gttgcttcaa
    22861 cgccagcagc tgatatcgcg gcaaactggg tttggaattt tggctatttt actgttaatc
    22921 gtatcggtta ccaagcccaa gttatcccag ccttgcttgc aggtttgagt ctgtcttatc
    22981 ttgaaatctt ctggcgcaag catatcccag aagtcatttc tatgattttt gtacctttct
    23041 tgtcattgat tccagccttg attttggctc atactgtttt gggaccaatc ggttggacaa
    23101 ttggacaagg actttcatca gttgtcttgg caggtttaac tggtccagtt aaatggctct
    23161 tcggtgcaat ttttggtgcc ctctacgctc catttgtcat cacaggtctg caccatatga
    23221 ccaatgccat tgatacacaa ttgattgcgg atgctggtgg cactgcccta tggccaatga
    23281 ttgctctttc taatattgct caaggctcag ccgtgtttgc ctattatttc atgcatcgcc
    23341 atgatgagcg tgaggctcag gtttcacttc ctgcaaccat ttcagcctat ctcggtgtta
    23401 cagaaccagc tctttttggg gttaacgtaa aatatattta tccatttgtt gctgggatga
    23461 ctggttcagc ccttgcaggc atgttatccg ttacttttaa tgtaactgcg gcttctattg
    23521 gtatcggtgg tttgccaggt attctctcta ttcaacctca atacatgctg ccatttgcag
    23581 gaactatgct agttgcgatt gttgttccaa tgctcttgac tttcttcttc cgcaaggctg
    23641 gtctctttac aaaaacagag ggcgatacga acttgcaggc agaattcgtt gctcaagaag
    23701 aagcagaatt tgtgaaccat gaaccagtag aacttacttc ggtagaaatt atcagcccac
    23761 taactggcca agtgaaagaa ttgagtcaag cgacggatcc tatttttgca tcaggtgtca
    23821 tggggcaagg tctagtcatt gaaccaagcc aaggtgagtt gacctctcca gttaatggga
    23881 cagtgacggt tcttttccct accaagcatg ccatcggcat tgtctctgac gagggagttg
    23941 aattgctcat ccacatcggt atggatacag taggtcttga tggcaaaggt tttgaaagtc
    24001 ttgtagtcca aggagatcac gttacagttg gtcagcaact gattcgtttt gatatggatg
    24061 tcattaaggc tgcaggtctg gtgacagaaa ctcctgttat catcaccaac caagatgctt
    24121 atacagcgac tattcccgga acttatccga caacgatcca agctggagca tctctcatgg
    24181 tcgctacacg aatctaatac tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca
    24241 acctcaaaat agtgttttga gcaacctgtg gctagcttcc tagtttgttc tttgattttc
    24301 attgagtata attgaaatag cacaaatagg gacggaagac tgcttcctcc cttttatcag
    24361 aaaaggagaa acagatgaca cttgataaag gaaaagtagt ctatcaaatc tatccaaaat
    24421 cttacaaaga caccactgaa aacggtattg gggatttccg tgggattatc gaaaaaattc
    24481 cctatttagc caaactaggt gtggatatgg tctggctcaa tccattctat ccaagccctc
    24541 aacgggataa tggttacgat atttcagatt atatggcagt ggatcctctt tttggtgata
    24601 tggctgattt tgaggaaatg gtgtgtgtcg gtaaagagca caagattgac tttatgctgg
    24661 acatggtact taatcattgt tcgacagagc atgaatggtt tcagaaagcc ctagctggtg
    24721 ataagtatta tcaagacttt ttcttcatcc aagaccaacc aacagattgg cagtctaagt
    24781 ttggtggttc tgcatggacg cctttcgggg atactgggaa atactatctt cacctatttg
    24841 atgagaccca ggctgacctt aactggcgca attccaatgt ccgtaaggag cttttcaagg
    24901 ttgttaattt ctggcgcgac aagggtatca aaggtttccg atttgatgtg atcaatttga
    24961 tcggtaagga cgaggtttca gtggactgtc ctgaaaatga agggaagcca gcttatacag
    25021 acaaacccat cgttcataac tatttgcgta tgatgaacca agccactttt ggatctgacg
    25081 atagctttat gacagttggg gaaatgtctt ctaccaccat ggaaaactgt gtcctctatt
    25141 cgtcgcctga tcgtcaggaa ttatccatga cctttaattt tcatcacctc aaggtggact
    25201 ataaggatgg acaaaagtgg accttggctc cctttgattt tgaagagttg aagagtcttt
    25261 accatagttg gggtaaggaa atgagtgata aagacggttg gagtgccctc ttttggaaca
    25321 atcacgatca accacgtgcc ttgaaccgtt ttgtcgatat tcaaaacttc cgcaaggaag
    25381 gagccaccat gctagcggct agcattcacc tgtcacgtgg gacaccttat atctatatgg
    25441 gtgaagaaat cgggatgatt gacccagact atgattctat ggctgattat gtggatgtcg
    25501 aatcgcttaa tgcctatcag acgctcttag aagaaggaaa gagtcagcaa gaagccttcc
    25561 agattattca agctaagtcg cgtgataatt cacgcattcc catgcagtgg gatgcttcgg
    25621 aaaatgcagg attttcaaca ggcactccat ggttgaaagc tggtaaatcc tataaataca
    25681 tcaatgtaga aaatgaaatc cagggtccga ttttcacctt ctatcaagac ttgattcgac
    25741 tgcgtaagga aatgccaatc atttcagaag gaagttacaa accagccttt gaagatagca
    25801 aacaagtcta cgcttttgaa cgccagtttg aggatcaaaa gttactagtg ctcaataact
    25861 tttatgctaa agaagtggaa atcgacttgc cagcagtcta ccaaaatgga cagattttga
    25921 tatcaaacta tgaagatgca gaagtgtctg agaaaattct actcaaaccc tatcaaacac
    25981 tggctattta tgtaaattaa tactcttcga aaatctcttc aaaccgtgtc agttttatct
    26041 gcaacctcaa agcggtgctt tgagcaacct gtggctagct tcctagtttg ctctttgatt
    26101 ttcattgagt ataaacttag caaggagacc tctttttcag aaaagcagcg ttctttttgc
    26161 tgtctattcc atccctgaaa gtgtagaaca aactggtcag ggtggctagt ttgtggtata
    26221 atgaaaggga ttcaaaaaga aacaggagaa aaatgatgga tttactttta gcaattgtat
    26281 tgattgtgct agcttttcta ggaggagctc ttggaggaat gtacttggtt cgtaagcaaa
    26341 tcgaaaaaga atttgctgac aacccacgtt tgaatgctga agcagttcgt actcttttga
    26401 gtgcaaatgg tcaaaaacca agcgaagcta aggtacaaca agtttaccac caaatcatcc
    26461 gccaacaaaa ggcagccctt gctaacaata aaaagaaaaa ataaataagg aaaagtctgg
    26521 gatgaaagtt ccagacttct cactatgttg gttatggttt agggatgaga ctttttcctt
    26581 gcattctatt gatatttgat tatgattaag agagaggtag ttgacattct atcaagctgt
    26641 cggtcagttc gttcagtaca aggaatcata atgaacgatc aatcagaaaa aagactagaa
    26701 agaagactgt atggataatc gaccaattgg ttttttggat tcgggtgtcg ggggcttgac
    26761 cgttgtgcgc gagctcatgc gccagcttcc ccatgaagaa atcgtctata ttggagattc
    26821 ggcgcgggcg ccctatggcc cccgtcctgc tgagcaaatt cgtgaatata cttggcagct
    26881 ggtcaacttt ctcttgacca aggatgtcaa aatgattgtc attgcttgta acactgcgac
    26941 tgcggtcgtc tgggaagaaa tcaaggctca actagatatt cctgtcttgg gtgtaatttt
    27001 gccaggagct tcggcagcca tcaagtccag tcaaggtggg aaaatcggag tgattggaac
    27061 gcccatgacg gtacaatcag acatataccg tcagaaaatc catgatctgg atcccgactt
    27121 acaggtggag agcttggcct gtcccaagtt tgctcccttg gttgagtcag gtgccctgtc
    27181 aaccagtgtt accaagaagg tggtctatga aaccctgcgt cccttggttg gaaaggtgga
    27241 tagcctgatt ttgggctgta ctcattatcc actccttcgc cctattatcc aaaatgtgat
    27301 ggggccaaag gttcagctca tcgatagtgg ggcagagtgc gtacgggata tctcagtctt
    27361 actcaattat tttgaaatca atcgtggtcg cgatgctgga ccactccatc accgttttta
    27421 cacaacagcc agtagccaaa gttttgcaca aattggtgaa gaatggctgg aaaaagagat
    27481 tcatgtggag catgtagaat tatgacaaat aaaatttatg aatataagga tgaccaggac
    27541 tggtatgttg ggtcttatag tatttttggt ggcgttaaca gtttgagcga ctatcagaca
    27601 gattttcctc tgtttgaatt ctccaaaata tttggagatg aagagtatgg tttcccgctt
    27661 tcagttactg ttttacgcta tggttctacc taccgtttgt tctcctttgt ggtagatatg
    27721 cttaatcaag aaatgggacg aaacttggaa gttattcaac gtcatggggc cctgctcttg
    27781 gttgaaaatg ggcaactctt gtatgtagaa ttgcctaaag aaggggtcaa tgttcatgat
    27841 ttctttgaga caagcaaggt cagagaaacc ttgttgattg cgactcgtaa cgaaggtaaa
    27901 accaaggaat tccgagctat ctttgataag ttaggctacg atgtggaaaa tcttaatgac
    27961 taccctgacc tgcctgaagt agcagaaaca ggtatgacct ttgaagaaaa tgcccgcctt
    28021 aaggcagaaa ccatttctca attaacgggc aagatggttt tggcagatga ttctggtctc
    28081 aaagtcgatg tccttggtgg cttaccaggc gtctggtcag ctcgtttcgc aggtgtggga
    28141 gcaactgacc gtgaaaataa tgccaaactc ttgcacgaat tggccatggt ctttgaactc
    28201 aaggaccgct cggctcagtt ccacacaacc ctagtcgtag ccagcccaaa taaggaaagt
    28261 ttagttgttg aagcagactg gtcaggttat attaactttg aacctaaggg tgaaaatggc
    28321 tttggctatg atcccctctt ccttgtagga gagacaggtg agtcatcagc tgaattaacc
    28381 ctggaagaaa aaaatagtca atctcaccgt gccttagccg ttaagaaact tttggaggta
    28441 tttccatcat ggcaaagcaa accatcattg taatgagcga ttcccatggc gatagcttga
    28501 ttgtggaaga agtccgtgat cgctatgtgg gcaaagtcga tgccgttttt cataacggcg
    28561 attctgaact acgtccggat tctccacttt gggagggcat ccgcgttgtt aaagggaaca
    28621 tggacttcta cgccggctac ccagaacgtc tggtgactga gcttggttcg accaagatta
    28681 tccaaactca tggtcacttg tttgacatca atttcaactt tcaaaagttg gactactggg
    28741 ctcaggagga agaggccgct atctgcctct atggtcactt gcatgtgcca agtgcttgga
    28801 tggaaggcaa gatcctcttt ctaaatccag gttctatcag ccaaccacga ggtaccatca
    28861 gagaatgtct ctatgctcgt gtggagattg atgatagtta cttcaaagtg gactttttga
    28921 cacgagatca cgaggtgtat ccaggtttgt ccaaggagtt tagccgatga ttgccaagga
    28981 gtttgagact ttcttgttgg ggcaggagga aacttttttg acccctgcta aaaatctagc
    29041 tgtgttgatt gatacccaca atgcggatca tgcgaccctc ttgctcagtc agatgaccta
    29101 tacccgtgtt cccgttgtga cagatgaaaa acagtttgtt gggacgattg gactcagaga
    29161 tattatggct tatcagatgg agcatgactt gagccaagaa atcatggcgg atacggatat
    29221 cgttcatatg acaaaaacgg acgtagcggt tgtttcgcct gatttcacca ttacggaggt
    29281 cttgcacaag ctagtagatg agtccttctt accggttgtg gatgcagagg gtattttcca
    29341 agggattatt acgcgcaagt ccatcctcaa ggccgttaat gccctcttgc atgactttag
    29401 taaggaatat gagattcgat gccaatgaga gacaggattt cagccttttt agaggaaaag
    29461 cagggcttgt ctgtcaattc caagcagtcc tataagtatg atttggagca atttttagac
    29521 atggtaggtg agcggatttc tgagaccagt ctcaagattt accaagccca gctagccaat
    29581 ctaaaaatca gcgcccagaa gcgaaagatt tcggcctgta accaatttct ctactttctc
    29641 tatcaaaaag gagaggtgga cagcttttac cgcttggaat tagccaaaca agctgaaaag
    29701 aagacggaaa agccagagat tctataccta gactcttttt ggcaggaaag cgaccatcca
    29761 gagggccgct tgctagcgct cttaatccta gaaatggggc tcttgcccag tgagatttta
    29821 gccatcaagg ttgcggacat caatctggat tttcaggtgc tgcgaatcag caaggcttcc
    29881 caacagagga ttgtcaccat tcccacggcc ttgctttcag aattggaacc cttgatgggg
    29941 cagacctatc tttttgaaag aggagggaaa ccctattctc gtcagtgggc ctttcgtcag
    30001 ttagaatctt ttgtcaagga gaaaggtttt ccatccttat cagctcaagt cttacgtgaa
    30061 cagtttattc taagacaaat agaaaacaag gtcgatttgt acgaaattgc aaaaaaatta
    30121 ggattaaaaa cagtcctgac cttagaaaaa tatagataat ggatattaaa ttaaaagatt
    30181 ttgaaggacc cctggactta ctcttgcatc tggtttctaa gtaccagatg gatatctacg
    30241 atgtgcccat tacggaagtc atcgaacagt atctagccta tgtctcaacc ctgcaggcca
    30301 tgcgtctgga agtgacgggt gagtacatgg tcatggctag tcagctcatg ctgattaaga
    30361 gtcgtaaact ccttccgaag gtagcagaag tgacagactt gggggatgac ctggagcagg
    30421 acctcctctc tcaaatcgaa gaatatcgca agttcaagct cttgggtgag cacttggaag
    30481 ccaagcacca agaacgggcc cagtattatt ccaaagcgcc gacagagttg atttacgaag
    30541 atgcggagct tgtgcatgac aagacgacca ttgacctctt tttgactttt tcaaatatcc
    30601 tagccaagaa aaaagaggag tttgcacaaa atcacacgac gatcttgcgg gatgagtata
    30661 agattgagga catgatgatt atcgtgaaag agtccttgat tggacgagat caattgcgct
    30721 tgcaggattt gttcaaggaa gcccagaatg tccaagaggt catcaccctc tttttggcaa
    30781 ccctagagtt aatcaaaacc caggagttga tcctcgtgca agaggagagt tttggagata
    30841 tctatctcat ggaaaagaag gaagaaagtc aagtgcctca aagctagact tgatagagag
    30901 gaaagatgag tactttagca aaaatagaag cgctcttgtt tgtagcgggt gaagatggga
    30961 ttcgggtccg ccagttagct gaactcctct ctctgccacc gacaggcatc cagcaaagtt
    31021 taggaaaatt agcccagaag tatgaaaagg acccagattc cagtttggct ttgattgaga
    31081 caagtggtgc ttatagattg gtgaccaagc ctcaatttgc agagattttg aaggaatact
    31141 ctaaggcgcc tatcaaccag agcttgtctc gggctgccct tgagaccttg tccattattg
    31201 cctacaaaca gccgattacg cggatagaaa ttgatgccat ccgtggagtt aactcgagtg
    31261 gagccttggc aaagttgcag gcttttgacc tgataaagga agacgggaaa aaggaagtat
    31321 tggggcgccc caacctctat gtgactacgg attatttcct agattacatg gggataaacc
    31381 atttagaaga attaccagtg attgatgagc ttgagattca agcccaagaa agccaattat
    31441 ttggtgaaag gatagaagaa gatgagaatc aataagtata ttgcccacgc aggtgtggcc
    31501 agtaggagaa aagcagaaga gctgattaag caaggcttgg tgacggttaa cggccaagtg
    31561 gtgcgtgaac tagcaaccac tatcaagtca ggcgacaagg tcgaagttga aggtcaacct
    31621 atctacaacg aagaaaaggt ctactatctg cttaacaaac cacgcggtgt gatttccagt
    31681 gtgacagatg ataagggtcg caagacggtt gtcgacctct tgcccaatgt caaagagcgt
    31741 atttaccctg tgggtcgttt ggactgggat acatcaggtg tcttgatttt gaccaatgat
    31801 ggggacttta cagacgagat gattcaccct cgtaatgaga ttgacaaggt ttatgtcgcg
    31861 cgtgttaaag gtgtggccaa taaggacaat ctccgcccct tgacccgtgg tcttgagatt
    31921 gatggtaaga aaaccaagcc agctgtttat gaaattctca aagtggaccc agtcaaaaat
    31981 cgctctgtgg tgcagttgac catccatgaa gggcgtaacc atcaggttaa aaagatgttt
    32041 gaagctgttg gtctccaagt agataagttg tctcggactc gtttcggaca cctagacttg
    32101 acaggactcc gtccaggaga atcccgtcgt cttaataaaa aagaaatcag ccaactacac
    32161 accatggctg taactaagaa ataatgaaac gaattttaat agcgcctgtg cgcttttacc
    32221 aacgttttat ctcaccagtc tttccaccct cttgtcgctt tgagctgact tgttccaact
    32281 acatgattca ggctattgaa aaacatggtt ttaagggggt attgatgggc ttggctcgga
    32341 ttttacgttg tcatccctgg tcgaaaacag gtaaggaccc cgttccagac cacttttccc
    32401 ttaaacgaaa tcaagaaggg gaatgaggtg gggtaaatag atttcaaaat gataaaaacg
    32461 catcctatca ggtttgagtg aacttgatag gatgcgtttt agaatgtcaa aattttatac
    32521 tcttcgaaaa tcccttcaaa ccgcgtcagc tttcatctgc aacctcaaaa cagtgttttg
    32581 agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat taaattgagt
    32641 ttgaagtggc ttatttcaaa gctttttgta tgtcttcaat catgagtttt gttgattcaa
    32701 gtccgcctcc gcttagatac cagaggtctg gtgttagttg gataatctta ccatttttag
    32761 cagcaggtgt ttcagcgata agggcatttt ctaggacacc gtcgttgcta gagttgtccc
    32821 caccgatggc aagggtacgg ttgatgacaa agaggatgtc agggttgatt tctttgacac
    32881 tttcaaagct gacttcttgt ccgtggcgtg agtcttcaaa ttttgtatca gttggtttga
    32941 atttcaaggt ttggtacaag aaagagaaac gagatttggc accaaaggct gccatttttc
    33001 cttcattaag gaggatcgta agggcttttt tgtcagagct ttcattttta gtagcgactt
    33061 cttggatgct cttgtctagc ttggccaatt cttccttggc tttctgtgta ccagtttcgc
    33121 cgaaggcact tgctaaggat tcgatattag ccttggtaga agtccagtag tcgtccttgc
    33181 ttgcttggaa gagaacggtt ggggcgattt ctttgaattt gtctacgaat ttttgtgtac
    33241 gtggtgaagc gataatcaaa tcaggctcaa gggcggcgat agcttctaaa tcaggttctt
    33301 tcatagaacc aacatttttg acagttccca ctaggtcttt tagataagtc ggaacagttt
    33361 ttgtaggcat tccgacgata tttttttcaa atcctaaagc gcgaatagta tccgcagcgc
    33421 cgaggtcaaa ggtcacaatc ttttcaggaa ctttggaaag tttgacctcg tccagtgaac
    33481 ttttaatggt tatctctgtt ggagcagagc tactggtctc tgtctgacta gtgcttgagt
    33541 ttgtactaca tgcaccaagt aggagcaaga agctggccac tagggcagtg aaataaagtt
    33601 taagggatgt tttcataatt tttccttttt aaaatgtgat aacgatttag ggagtctctt
    33661 aatcttattg actaagagac tgaaggttct ctaacttgag cttttatgtt actagctata
    33721 gatacagatc tttttgtcat tgatatcagc tagcgtgatg ggaatctcat aaagttgact
    33781 gagcaggtca gcctgcatga tttgatcggt tcttcccttg ctaaagacct ggccgtcctt
    33841 gaaggcgaca atttcatctg catactgact ggccatgttg atatcgtgga ggacgatgat
    33901 aatggtcttg ccgagttcct ccaccagtcg tcgaagaatc tgcatcatgc tgacgctttg
    33961 cttgatatcg agattgttga gtggttcgtc cagcaagata aagtccgtat cctgggccag
    34021 taccatagcg ataaagacgc gctggagttg cccccctgac aggctattga tgtagcggtc
    34081 ttttaagttg gtcagttcca aatagttcag agtttctcgg attttttccc agtcttctga
    34141 tctaagtcga cctcggctgt agggaaaacg tccaaaactg accagttctt caacagtcaa
    34201 tttggcttgg taattgattt tctgttttag gatggttagt tcttgggcca gttcttgcga
    34261 attccagctc tcgatttcac gtcctttgat actgagaact ccctgatctt tcttggttag
    34321 tctgctcatg atggagagga gagtcgattt tccagcacca tttggaccaa taaaggctgt
    34381 cagtttttga ggactgactt caagcgaaat gccttgcaaa atatcctgtt tttgaatgga
    34441 tttgtcaatg ttttccagtt tcactgacga gccctcctat atagtaagat aaagaataag
    34501 aagccaccca cactctcaat gatcatactg atacgaattt ccagtgcaaa gactcgttca
    34561 atcaaggctt gccccaaggt taagctaata aatccaacca gaatggccac tataaagagt
    34621 aacttgtgct gatagtcttt gacaatcagg taggtgaggt tggccagcat aaagccgaag
    34681 aaggccatag gtcctaccaa ggcagtggcc gttgaggtca aaagcacgat tccccagagg
    34741 agctctttct gttctttttc aacatcgagt cccaatatct gagccgtttc tctttgcagg
    34801 tgcaagacat ctagaacgac tgcttttcga aagaaaaaga ttgtcaaagc gaggatgatc
    34861 agagaaccga tggctaggat ggaagtgttg agatgttgaa aggaggcaaa aagactattt
    34921 tgcagtttat cgtattcgtt tggatccatt aggacttgaa ggaaggtgct gatatttcga
    34981 aagagacttc tgagcgctag acagatcagc aggatgaaga ccaggtcttg cttcatcagt
    35041 gtcttcaagt aaccttgtaa ggcgagaaag aagagggact ggacaagaag taagactagg
    35101 aattctaaga taggggattt gccaagttga agaaacttgc tttcaaaaac cagtagtagg
    35161 gtttgtagta ggacgtagaa ggattcaatt cccaaaatac taggcgtcag gaagcgattt
    35221 tccgtcaggg tttgaaaact aatggtcgaa atcccagtcg cgatggctac caagagataa
    35281 acgatgatct tttgggaacg caacttccaa gcaaaggctg acaagtgagt gatgggccaa
    35341 aagtagagaa gacaagctcc gatggcaaga ataatgagaa tccagaagag cttggtatgt
    35401 ttgcttttag tctgcatctt ttcgtccccc tctccagaga agtaggataa agacgagact
    35461 accgatgatt cctagcaaga gactgacaga caactcatag ggcctaatca gaactcggga
    35521 taggatatcg caagccagaa ctagattggc accaaccagt gcgaccatga gtttggtttg
    35581 acttagatta tctccatagc gcttgcgaac aagattggga acgataactc cgagaaatgg
    35641 taagccaccc acggtaatca tggtgacgct tgtcgttagc gccaccagaa agagggccag
    35701 tttttcaagt agggagtagg aaatccccaa actctcgctg gtttctttcc ctagattcat
    35761 gatggtgaag gtttgggata atttccaaac ggttatcagg atgatgaggc ctaagaagag
    35821 ccactcatac tgatgggtct gaatcatgga gaaggagccc tgggtccagg cagtcatact
    35881 ctgaaccaga ttgaaacgat aggcgataac ttctgtgact gagccgataa tcccgctata
    35941 gatgatccca atcagaggca acatccacct ttcctttaca gtaaaaatgg tcataaaggc
    36001 taggaagaag agggtgaata cgatggatga aacaaaagcg aagagcatct tttgggtcag
    36061 actagccgat ggaaagacaa aaaggctcag caccattccc agtttggcgg cttcagtcgt
    36121 tccaactgta ctcggtgcag caaactgatt ttgggtaata gtctgcatga gaaggcctgc
    36181 catactcata ctagaggcag tcaggagaat actgatagtt cttgggagac gggactcttg
    36241 aaagaggagc caggtctgct ggtcgaaatc aaatagcttt ccccatgaaa aatcactggt
    36301 cccaatgcta atagagagaa agactaggag tagaagtaag ccaattaaat aatgagaaag
    36361 tttcataccc cgtcctttca tgtagatttg gtatcgaaag atatctgcgg atataaatgt
    36421 aacattattt ttctaatctg tcaataaaat ttctgacaat ttaataaata caacaaggag
    36481 agagcaacaa gattttctcc tttgttatcc tattctaaaa tgtttttacc ttaatctgat
    36541 aaaataatat cttcgaggga gtagctagcc gtccaatcaa gatattgttt agcttttgaa
    36601 gcatctgcta ggacactggc tgggtcacta gcacgtcgag caacaatctc gtgtgggatt
    36661 ttttaattta gtaattcttc agcagtttta aagatttctt tgatagtata gtctttttta
    36721 gttcctaagt taaagatttg agaagaactg tcttcttgaa ataggtagtt cattccttta
    36781 acatgagcct atgcaaggtc caagacataa atgtaatctc gaatacatga atcgtcacgt
    36841 gtatcgtagt catctccaaa tatttttaag ctatcatgtt gtcccaatgc ggtcttgttg
    36901 atatttggaa tgatgtgagt tggatttttc acacgcagac cgtttgaagc atccatttca
    36961 gccccagcaa cattaaagta acggaaaata acatatttcc agtcgtagcg attggccatc
    37021 cagtaaatca ttcgttcgcc catcagtttt gtctctgcat aagggttgac agggtcgagc
    37081 agggtatctt cagtcaccgg cttgtcaata cagttatttc catagagaga agcagtcgaa
    37141 gagaacatga ttttttgaat gccaacttca gataagactt tgagaacttg gttcatacca
    37201 gcaacgttgg cagtgaagta tttacttgga ttttcaatac tttcgctcac aacaatttca
    37261 cctgcacaat ggaggacagc atcaatctga ttttcttcta agtaagcctt taaggcgcta
    37321 gcatcataaa catccagttc tttaaagcta gcacgactat ccacagccgc tcgatttcct
    37381 gtggagagat tatcgaggac atgcacctga tagccagcat ttaaaagagc tttaacggta
    37441 tgggagccaa tgtagctagt cccacctgta acaagaattg ttttggtcat gattttttcc
    37501 ttttctagtt ttgtactata gtaaattgaa ataagatatg aacaactcta ttaggaaagt
    37561 caaattaatt tctagaaatg ttttagcagc tacagcgtac tattccaaac tcaaccaact
    37621 atatatttaa agaaagaaga aagggaagtc aactattttc tgtaaatttc atgaaaaatc
    37681 caaacaactt tgatggtgta ttgttttttt gtttggaaat aaatattcga gttaattttg
    37741 gaatgtttac tagattttgc actacatgca agagaatact atccttttct aagatagagc
    37801 aggactaaga tactaactta gaaatccacc ttcccactat ccttctccta taaaaagtgg
    37861 taaaatggat gaaagaaaga aggaactgaa atgacaacat tattttcaaa aattaaagaa
    37921 gtaacagaac ttgctgcagt ctcaggtcat gaagcgcctg tccgtgctta tcttcgtgaa
    37981 aagttgacac cgcatgtgga tgaagtggtg acagatggct tgggtggtat ttttggtatc
    38041 aaacattcag aagctgtgga tgcaccgcgc gtcttggtcg cttctcatat ggacgaagtt
    38101 ggttttatgg tcagcgaaat caagccagat ggtaccttcc gtgtcgtaga aatcggtggc
    38161 tggaacccca tggtggttag cagccaacgt ttcaaactct tgactcgtga tggtcatgaa
    38221 attcctgtga tttcaggttc tgttcctccg catttgactc gtggaaaggg gggaccaacc
    38281 atgccagcca ttgccgatat cgtttttgat ggtggttttg cggacaaggc tgaggcagaa
    38341 agttttggca tccgtcctgg tgataccatc gtaccagata gttctgcaat tttgacagcc
    38401 aatgaaaaaa atatcatctc aaaagcttgg gataaccgct acggtgtcct catggtaagc
    38461 gagctagctg aagctttatc aggtcaaaaa ctcggcaatg aactctatct gggttctaac
    38521 gtccaagaag aagttggtct gcgtggcgct catacctcta caaccaagtt tgacccagaa
    38581 gtcttcctcg cagttgattg ctcaccagca ggtgatgtct acggtggtca aggcaagatt
    38641 ggagatggaa ccttgattcg tttctatgat ccaggtcact tgcttctccc agggatgaag
    38701 gatttccttt tgacaacggc tgaagaagct ggtatcaagt accaatacta ctgtggtaaa
    38761 ggcggaacag atgcaggtgc agctcatctg aaaaatggtg gtgtcccatc aacaactatc
    38821 ggtgtctgcg ctcgttatat ccattctcac caaaccctct atgcaatgga tgacttccta
    38881 gaagcgcaag ctttcttaca agccttggtg aagaaattgg atcgttcaac ggttgatttg
    38941 attaaacatt attaaaccat aagggaggtg gtagggatgg tagaaccaaa cctagaaagc
    39001 cttataaaag atctttacaa tcatgctcga catgatttga gtgaagattt agttgctgct
    39061 ctcctagaga ctactaaaaa actgcctact acaaatgagc aattgcaggc agttcgtctc
    39121 tcaggcctgg tcaatcgtga attgctccta aatcccaaac atccagcacc tgagttgctc
    39181 aacttggctc gctttatcaa aagagaagaa gccaagtaca gaggaactgc gacttctgcg
    39241 cttatgtatg aggaactttt taaaatgctt tgattccatt gtggatcaaa gcatttttta
    39301 taagacctat ctcgtgagcg ttcaaatagt agtaacaagg aatcatgaga agtcagccga
    39361 gaccatagta gtgaagaaac ttctgtaatg gaagtggagt gaagtgagga atcgtcaaac
    39421 ggtaggggat aggctgtttg aagggtgcta cgaaaaagat agggtaaggt gaaattatag
    39481 cggaatgaaa taagatatga acaaattgat taggaaaatc aaatgaattt atagaaatat
    39541 tttagcagtc ataacgtcct attccagttt caaaatgtta taaatacgaa caaattgatt
    39601 gggaaattca aatcgctttc tatcaatgtt ttagaagata cagtgcccta gtctaacttc
    39661 aatatactat aaaagaacag atggaagcaa ttatgattta cttctatctt taaaataaat
    39721 gatctgatag gaaaaatgtg tcccctcata aaaaatagga tagtacggat ggaaggcttt
    39781 tgtagactgg aggacgaagg aatttagaaa ctctcgttaa aagttagttg agccggagta
    39841 tggtggtgtg aataattatc aaaaattatt tccaaatcga aatagttgac agttagaacg
    39901 atgagtgtta caattatttt attcatttcg acatcgaaat aaattggagg tgttatgaaa
    39961 gatagtcatt tgctagccca tcatattcgt ttgttgaatg ggcggatttt tcaaaagtta
    40021 ctgagtcaag atcctgaggc tctttatagg ggtgaacagg gcaagatttt agcggtttta
    40081 tggaatagtg aaactggctg cgcaactgcg acagatatcg cgcttgcgac tgggcttgcg
    40141 aataatacgc tgacgactat gataaaaaag ctagaggaac aaaagcttgt aattgttagt
    40201 ccgtgtggaa aagacaagcg taagaagtat ttagttttaa cggagttagg caagtcccag
    40261 aaagaagtgg ggcatcgtgt cagtcagaaa ttggatacta tcttttacaa aggattttca
    40321 gaggaagaaa ttcaccaatt tgaaggtttt caagaaagaa ttttggcgaa tttgaaagag
    40381 aagggaaatg aggtttagaa tatgtcacaa caagtgaaaa atgctcacaa cctatacatc
    40441 catgccattc aagacggacg agttgctgag gctcaagccc agtctgtagg ggatacctat
    40501 atccaacatt cgacaggtgt tcctgacggg aaagaaggat ttgcagtctt ctttgcagat
    40561 ttctttgagc gtcatccaga gcgtcagatt aagattgtcc gcaccattga ggatggcaat
    40621 ctggtctttg ttcatgttca tcaatatctg aatggtggag aagctcaatg ggtgacgacg
    40681 gatactttcc gtgcggatga gaatggtcgt attgttgagc attgggatgt cattgactac
    40741 tatcgaacac ctgaaaatga ccaactagat caaatttttg gagattttga aatcaaggat
    40801 ttggacaaga aagcagaaaa taaaaagctg gttcgccgtt tcttgacaga aattttccaa
    40861 aatggggagc tagagcagtg gagtgattat gtggcagacg atttgattca gcataatcat
    40921 gagattggac aaggaagtgc tgcttataaa aactatgtgg ctgaatatag tgtcactttt
    40981 gactttgttt tccaactctt aggacaagga aactatgtgg ttagctatgg tcagactcag
    41041 attgatggcg ttgcttatgc ccagtacgat atcttccgtt tagagaacgg gaaaattgtg
    41101 gagcattggg ataataagga agtcatgcct aaggtagaag acttgaccaa tcgagggaag
    41161 ttttaaattg aggacaaaga atgattgaat acaaaaatgt agcactgcgc tacacagaaa
    41221 aggatgtctt gagagatgtc aacttacaga ttgaggatgg ggaatttatg gttttagtag
    41281 ggccttctgg gtcaggtaag acgaccatgc tcaagatgat taaccgtctt ttggaaccaa
    41341 ctgatggaaa tatttatatg gatgggaagc gcatcaaaga ctatgatgag cgtgaacttc
    41401 gtctttctac tggttatgtt ttacaggcta ttgctctttt tccaaatcta acagttgcgg
    41461 aaaatattgc tctcattcct gaaatgaagg ggtggagcaa ggaagaaatt acgaagaaaa
    41521 cagaagagct tttggctaag gttggtttac cagtagccga gtatgggcat cgcttaccta
    41581 gtgaattatc tggtggagaa cagcaacggg tcggtattgt ccgagctatg attggtcagc
    41641 ccaagatttt cctcatggat gaaccctttt cggccttgga tgctatttcg agaaaacagt
    41701 tgcaggttct gacaaaagaa ttgcataaag agtttgggat gacaacgatt tttgtaaccc
    41761 atgatacgga tgaagccttg aagttggcgg accgtattgc tgtcttgcag gatggagaaa
    41821 ttcgccaggt agcgaatccc gagacaattt taaaagcgcc tgcaacagac tttgtagcag
    41881 acttgtttgg aggtagtgtt catgactaat ttaattgcaa cttttcagga tcgttttagt
    41941 gattggttga cagctctatc tcaacatttg cagttgtcac ttttgacctt gttactagct
    42001 attttgcttg cgattccctt ggctgttttt cttcgctatc atgagaagct ggccgactgg
    42061 gtcttgcaga ttgcaggtat tttccagacc atcccgtctc tggccttgtt ggggctcttt
    42121 atccctttga tgggaattgg gaccttgccg gctttgacag ctctagtgat ttatgcgatt
    42181 ttccctattt tgcaaaatac tatcactggg ctgaagggaa ttgatccgaa cctgcaagag
    42241 gctgggattg cctttgggat gaccagatgg gaacgtctca agaaatttga aattccactt
    42301 gccatgcctg ttatcatgtc tgggattcgg acggcagctg ttttgattat cggtacggca
    42361 accttggcgg ccttgattgg agcaggggga ctgggttcct ttatcctgtt gggaattgac
    42421 cgtaataatg ccagtttgat tttgattggg gcactttctt ctgcagtgct tgctattgcc
    42481 tttaacttcc tactaaaagt aatggaaaaa gcaaaattac ggacgatttt ctcaggtttt
    42541 gccttggtga cggtattgct gggtctatct tatagtccag ccctcttggt tcaaaaagag
    42601 aaagaaaacg tgattattgc agggaaaatt ggtccagaac cagaaatttt ggctaatatg
    42661 tataaacttt taatagaaga aaatacaagt ctaacagcaa ccgttaagcc taactttggg
    42721 aaaacaactt tcctttatga agcgttgaaa agcggagaca ttgatatcta tcctgaattt
    42781 actggtacgg tgactgaaag tttgcttcaa ccatcaccta aagtgagtca tgagccagag
    42841 caggtttatc aggtggcgcg tgatggcatt gccaaacagg atcatctagc ctatcttaaa
    42901 cccatgtctt atcaaaatac ttatgctgta gctgttccga aaaagattgc gcaagaatat
    42961 ggcttgaaga ccatttcgga tttgaaaaaa gtggaaggtc agttgaaggc aggctttaca
    43021 ctcgagttta acgaccgtga agatggaaat aagggcttgc aatcaatgta tggtctcaat
    43081 ctcaatgttt caaccttgga acctgctctt cgctatcaag cgattcagtc aggtgaaatt
    43141 caaattacag atgcctattc gactgatgcg gaattggagc gttatgattt acaggtcttg
    43201 gaagatgaca agcaactctt cccaccttat caaggggctc cactcatgaa agaagctctt
    43261 ctcaagaaac atccagagtt ggaaactgtt cttaataaat tggctggtaa gattacagaa
    43321 agccagatga gccagcttaa ctatcaagtc ggtgttgaag gcaagtcagc aaagcaagta
    43381 gccaaggagt ttctccaaga acaaggtttg ttgaagaaat gatgggacag agactttaaa
    43441 catactgaac tcaacttcct taaacgacta gataaaagaa tgctcagaca atttcgtctg
    43501 ggcttttttg atgtgagaat gactgaatgt cacttaaaat ggaaagaaag agaaaatttt
    43561 catgattttc taaaatttta ctgtaaagac agttgactat tcataaaata ggtgtataat
    43621 attttgtgaa ctacttaaca aataagaggt ttcagctcat gtcgactaag gttagaaatc
    43681 ttgtgtatag gcagttcatt atctaataga gcgttgcgtc cgaaagtcta tccagacacg
    43741 gctctttaaa aacaaaagga gaaatgatgc atacttattt gcaaaagaaa attgaaaata
    43801 tcaaaacaac cctaggtgaa atgtcaggtg gttaccgtcg tatggttgcg gctatggctg
    43861 atttaggatt ttcaggaact atgaaggcta tctgggatga cctctttgcc catcgtagtt
    43921 ttgcccagtg gatttatttg ctggttttag gaagttttcc tctctggctg gagttggttt
    43981 acgaacatcg tattgttgac tggattggga tgatttgtag cttgacaggg attatctgtg
    44041 taatctttgt atcggaaggt cgagcaagta attatctttt tggcttgatt aactctgtta
    44101 tttaccttat tttggcccta cagaaaggct tttatggtga ggtgctgacg acactttact
    44161 tcacagtcat gcagccaatt ggacttctag tttggattta tcaggcacag tttaagaagg
    44221 aaaagcagga gtttgtcgcg cgtaaactgg acggcaaggg ctggacaaag tatctttcca
    44281 ttagtgtgct ttggtggttg gcctttggct tcatttatca gtctattggt gccaatcgtc
    44341 cctatcgtga ttcaatcaca gatgcaacca atggggtagg gcaaatcctc atgacagctg
    44401 tttaccgtga acagtggata ttctgggcgg ctaccaatgt cttttcaatc tatctctggt
    44461 ggggagaaag cctgcaaatt caagggaaat atctaattta tctcattaac agtctagttg
    44521 gttggtatca atggagcaag gcagctaagc aaaatactga tttacttaac taggaaaaga
    44581 tgtttgaaag tgctgttttg agatttcgat taaaacagat atagttgata atcaaggatt
    44641 tatagtatga aaaagaggat cggcgggtcc tcttttgttg ttgaaaagat aaaaaactca
    44701 gtaacctaga aataagacaa ctgaagcttt actctatatt caatttttag gaatgagaag
    44761 gtctagataa aattggacaa cttcctggtc tgtgaaatct tgaccttttt tgagccacca
    44821 ggtcaatgtc tcgataaagt tggacacgac caagtgttgg aggtaagaag taggcagatt
    44881 agggtgggct tcttttaaat tatcagctag cacggaatag acatggtgtt ctagctcttt
    44941 atggagttga cggaggaagt agtcattttt ggaaaatagc agactggtga tatggtcttg
    45001 gtttttatga aaatggagaa agaggtgggc gaggtagtcc tcggttgaaa tggcttgctc
    45061 tctttcaaaa agatgatgga agaggtagcg gcagagctgg tccagaagaa gctccttact
    45121 ctcatagtga cagtaaaagg tggatcgtcc cacatctgcg agatcaatga tatcctgaac
    45181 agtagtggcc tcgtagccct tagcattcaa aagttgtata aaagcttgat agatggcttt
    45241 tttggttttg ctgatacggc ggtcaatgtt agtcatatgg acacttaagg caaattgttc
    45301 agaactgaat aaagctgacg ttttgcttct atcctttctt tgagttttag tggataatga
    45361 taatgaacaa ggtgttcata aatctattat aacaaaggaa tgagaaatat gaaggcaaaa
    45421 tatgctgttt gggtggcttt tttcttaaat ttgacttatg ccattgttga gtttattgca
    45481 ggtggagtat ttggttctag cgctgttctt gctgactctg tgcatgactt gggagatgcg
    45541 attgcaattg gaatatcagc ttttctagaa acaatctcca atcgtgaaga agacaatcag
    45601 tacaccttgg gctataagcg atttagcctg ctaggagcct tggtaacagc tgtgattctc
    45661 gtaacaggct ctgttctagt cattttggaa aatgtcacga agattttgca tccgcaacca
    45721 gtcaatgatg aggggattct ctggttagga attattgcga ttactatcaa tctgttagcg
    45781 agtctggtgg ttggtaaggg aaagacaaag aatgagtcta ttctgagtct gcattttctg
    45841 gaagatacgc tagggtgggt agctgttatc ctgatggcga ttgttcttcg atttacggac
    45901 tggtatatcc tagatcctct tttgtccctt gtcatttctt tctttattct ttcaaaagcc
    45961 ctttcacgtt tttggtctac actcaagatt ttcttggatg ctgtgccaga aggtcttgat
    46021 atcaagcaag taaagagtgg cctggaacga ttggacaatg tggccagcct taatcagctt
    46081 aatctctgga ctatggatgc tttggaaaaa aatgccattg tccatgtttg tctaaaagaa
    46141 atggaacata tggaaacttg taaagagtct attcgaattt tcctaaaaga ttgtggtttt
    46201 caaaatatta ccattgaaat tgatgctgac ctagaaactc atcaaaccca taagcgaaag
    46261 gtgtgtgact tggaacggag ttatgagcat caacattaga aaaaagtgaa aaatacttgg
    46321 gtactatctt atttggaata gagtaatttc tttattattt aaatatttca aaaattggta
    46381 agagaagagc attgtataaa ctccagatat atgattgtta atgataaaaa tttttcgatt
    46441 agatacaaaa tgcttgactt ggagtcaact caaagttata taataagata agtgagttag
    46501 aatagcgtga actcagtgaa tgaaatgaga ggaggttagc gtgtgaatat taaatctgcc
    46561 agtgatttgt tggaaatttc agcggatacg attcggtatt atgaacgggt tggtcttgtg
    46621 ccaccgatta ctcgtactgc tactgggatt cgtgattttc aagatcagga tatcgaagcg
    46681 ctggaattta ttaagtgttt tcgttcggcg ggtgtctctg tagatagttt agttgactat
    46741 atgtcgctct accaaaaggg agatgaaacg agagaggaga ggcttggtat tttagaagag
    46801 gaaaagcaaa aattagagga gcgcttgtct cagatacaga cagctttaaa tcgtttaaat
    46861 ctcaaaatta aactttataa ggaaggaaaa ttttaaatga aatcagcagt atatacaaag
    46921 gcaggtcagg ttggacttgc tagcattgaa cgtccgcaaa taatagaagc ggatgatgtg
    46981 attattcgtg tggttcgtgc gtgcgtttgt ggttcagatt tatggaggta ccgtaatcca
    47041 gaaacgaaag ttggacacaa aaatagtgga cacgaagcga ttgggattgt tgaagaagct
    47101 ggggaagcca ttacgacggt gaaaccaggt gattttgtga ttgtcccttt tacacatgga
    47161 tgtggtgagt gtgatgcctg tcttgctgga tttgacggtt cttgcgacaa tcatattggc
    47221 aataatttgg ggggtgattt tcaggcagaa tatattcgct tccactatgc aaactgggcg
    47281 ctggttaaaa tccctggtca accttctgac tatacagaag ggatgctcaa gtcccttttg
    47341 actcttgcag atgtcatgcc gacaggctat catgcggcgc gtgttgcaaa tgttcaaaaa
    47401 ggggacaagg ttgttgttat cggtgatggg gctgttggtc aatgtgctgt catcgcggct
    47461 aagatgcgtg gagcatcaca aattatcctt atgagccgtc atgaagaccg tcaaaagatg
    47521 gctatggagt caggtgcgac agctgttgtt gcagaacgtg gtcaagaagg aattaccaag
    47581 gtgcgtgaaa tcctcggcgg aggagcagac gcagcacttg aatgtgttgg tacggaggct
    47641 gctatagaac aggcgctagg tgttcttcat aatggagggc gtatgggctt tgtaggagtc
    47701 ccacactata ataatcgtgc tcttggttcg acatttatgc aaaatatctc tgtagcaggt
    47761 ggggcagctt ctgctacaac atacgataag caatttttac taaaagccgt ccttgatggt
    47821 gatatcaatc caggtcgcgt ctttacttca agttataaac tggaagatat cgaccaagcc
    47881 tacaaagata tggatgaacg taagaccatt aagtctatga ttgtaatcga ataaaaaacg
    47941 aataggagtt ttagaactct attcgttttt tatgttatcc tattcttgat ttagggtact
    48001 ttctcttaat gtcagtctgg ttcccagcat ggtcaggcta gggattttcc gaccgtggag
    48061 gacttccttg ttaagaatat ccatacctgc tcggcccatt tcttcagtat aaactgtaat
    48121 actagagagg ggaggataga cctgtttggt cagactagtg tcgttaaagg aaatgaggct
    48181 gacgcgatct ggcaggctga ttccagcttc ttggagggca cggagggcac cgatagctaa
    48241 actatcgctg gctgcgaaaa atgctggcgg aagttggtct cccaagctct gaatggcctc
    48301 cttcattaag tcatagccag actgggcagt aaatcttcct tgaaagacca gttcatcatg
    48361 atagattccc ctcgcttgac tgtagttttt gaagttttct agacgcttgt cctgaatgat
    48421 ttcttcttgg tctgttgttt cttcaaggcc tgttagaatc ccgatacggt ccattccttg
    48481 actgaggaaa taatcgacaa cctgtttcat agcagtgtaa aaatccgtga taatacaggt
    48541 atgtcccagg gaaagtgtat cgctgtctag aaatacaaga ggcttttggt attcttcaaa
    48601 ggcagaaatc tgagctcgac taaactttcc gatgcagaga atcccaatca cttcctcgct
    48661 tagggtaaaa gggtggtcat taaaatagcg caagatatca tagtccaact cttgggctct
    48721 tttttctatt cctaggcgaa tctggtagta gtagaggtcg tccagctccc cttgttcgct
    48781 gacccattgg ataatggcaa tcttttgctt gggtttgtgg gactcgcctg tcttgaggtg
    48841 cttggtgtag cccagctctt cagcaacggt taaaatacgg tgtctggttt cttctgtaac
    48901 agataggctc tggtcgcgat tgaggacgcg ggatacggtc gcgatagaga cagaggctag
    48961 ctgtgcaatg tcttttaagg tagccataaa tcctccttga ttaggttagt atatcatgtt
    49021 tttcttcttt ttactgatat tttactaaaa ttttagtaaa aaggattgac cttggaaaat
    49081 tccttggata caatagaaag aaaacgatta cacgttaaga tggcttaacg gacagtcaaa
    49141 ggagaattca tatggcacaa catcttacta ctgaagccct tcgcaaagac tttcttgctg
    49201 tttttggtca agaagcagac caaaccttct tttcaccagg ccgcattaat ttgattggtg
    49261 aacatacaga ctacaacggt gggcacgttt ttcctgctgc tatttccttg ggaacttacg
    49321 gtgcagctcg taagcgtgac gaccaagtct tgcgtttcta ctcagctaac tttgaggaca
    49381 agggcattat cgaagtgcct ctcgctgacc tcaagtttga aaaagagcac aactggacca
    49441 attatccaaa aggtgtcctt catttcttgc aagaagctgg gcacgtgatt gacaaaggtt
    49501 ttgattttta tgtttatggg aatatcccaa atggtgctgg tttgtcttct tcagcatcct
    49561 tggagctctt gacaggagtt gtggcagagc atctctttga tttaaaacta gagcgtctcg
    49621 atttggttaa aatcggaaaa caaacagaaa ataactttat cggagtaaat tctggcatta
    49681 tggaccaatt tgctattggt atgggggctg accaacgtgc tatttactta gataccaata
    49741 ctttagaata cgacttggtg ccacttgatt tgaaggacaa tgtcgttgtt atcatgaaca
    49801 ccaacaaacg ccgtgaattg gcggactcta aatacaatga acgtcgtgct gagtgtgaaa
    49861 aagcagtgga agaattgcaa gttgccttgg atattcagac cctgggtgaa ttggacgagt
    49921 gggccgttga ccaatatagc tatctgatta aagatgaaaa tcgtttgaaa cgtgctcgcc
    49981 atgctgtgct tgaaaaccaa cgtaccctta aagctcaagc agcccttcaa gcaggtgatt
    50041 tggaaacatt tggtcgtttg atgaatgcgt cacacgtttc tctggagcgt gattatgaag
    50101 taactggttt ggaattggat actcttgttc acacagcttg ggcacaagaa ggagttctcg
    50161 gtgctcgtat gacaggggct ggttttggtg gctgtgccat tgccttggtt caaaaagata
    50221 ctgttgaggc ctttaaggaa gctgtaggca aacactacaa ggaagtagtt ggatacgctc
    50281 caagcttcta tatcgctgaa gttgcaggtg gcactcgcgt ctttgactag tcaaaaggag
    50341 gctctatagt gaccttagta gataaatttg taacacatgt catttctgaa agttcatttg
    50401 aggaaatgga tcgaatctac ctgaccaatc gtgttttggc acgagtggga gaaggtgttt
    50461 tggaagttga gaccaatctg gataaattga ttgacctcaa ggaccagcta gttgaggaag
    50521 ccgttcgatt agagacgatt gaggatagtc agactgcgcg tgaaatcctt ggtactgaat
    50581 tgatggactt ggtgactcct tgtccgagtc aggtcaatcg tgacttctgg gaagcctatg
    50641 tccactctcc tgagcaagcg atagaggatt tttatcaact cagtcagaaa aatgactaca
    50701 tcaaactcaa ggccattgct aaaaatatcg cttatcgtgt tccatctgat tatggagaac
    50761 ttgaaattac catcaatctc tctaagcctg aaaaggatcc gaaagagatt gcggcagcca
    50821 agttggtgca agctagtaat tatcctcagt gtcaactttg tttagagaat gagggttacc
    50881 atggtcgggt caaccaccca gctcgcacca accaccggat tatccgtttt gaaatggttg
    50941 gtcaggaatg gggtttccag tattcgccct atgcttactt taatgagcat tgtatctttt
    51001 tagatggcca gcatcgtccc atggccatta gtcgtcagag ttttgaacgt ctgttggcta
    51061 tcgtagagca gtttccagga tattttgctg gatctaatgc cgacctgccg attgtggggg
    51121 gctctattct aactcatgat cattatcagg gaggccgtca cgtatttcct atggaattgg
    51181 ctcccttgca aaagaccttc cgatttgctg gttttgagca ggtcaaggct ggaattatca
    51241 agtggccaat gtctgtccta cgcttgactt cggattccaa agaggatttg attaacttag
    51301 ctgataagat tttccaggaa tggcgtcagt attcagattc tagtgtgcag attttggcag
    51361 agacagacgg gacaccgcat cacaccatca caccaatagc gcgtaagcgt gatggacagt
    51421 ttgagttgga cttggtcttg cgagacaatc agacttcagc agagcatcct gatggcatct
    51481 atcatcccca caaggatgtc caacatatca agaaggaaaa tatcggcttg attgaggtca
    51541 tgggcttggc aatcttgcca ccacgtctga aagaagaagt ggagcaagtc gctagctatc
    51601 ttgtaggaga agctgttaca gttgccgatt atcatcagga gtgggcagac caactaaaat
    51661 cccaacatcc agacctaacg gataaagaaa aaacccttgc aatcgtcaag gactctgtgg
    51721 gtgctatctt tgtgcgtgta cttgaggatg caggagtcta caagcagaca gaacaagggc
    51781 agacagcctt tatgcgcttt gtggaacagg tcggaatttt actagactag gagctttctc
    51841 cttgcacagt cctataaaaa gtagtatcat agtgtcgttt gaaatatcgg gaggaaacga
    51901 tgaaagactt tcattttgac gctatatctg cctttgaaaa ttacgaaatt gaaaaaatga
    51961 gagatggtca cgttgtggtg acgaccaaag tagtgaactc gtcgctcaac tactatggca
    52021 atgcccatgg tggctatcta ttcacgctat gtgaccaaat cagtggtttg gtggttatct
    52081 cgctgggact tgatggggtg acactccaat cctctatcaa ctaccttaag gcaggaaaac
    52141 tcgacgatgt attgaccatt aaaggagaat gtgtccatca aggtcgtaca acctgtgtga
    52201 tggatgtgga tatcaccaat caagagggca gaaatgtctg taaagcaacc tttaccatgt
    52261 ttgtcacagg ccaaaggtct gaggaaagac gggtaagtat ataaagaaag gtgagtggga
    52321 taaatttatc tcactcattt ttaatttatg agatatgtta gaaggaaata taaaagagag
    52381 tgatgaaata caaatgtaat aggtacatat atgtggtata ctagttatag tagattttaa
    52441 ttgcttatat cgagtgagtt ctcatattag tgaggaattt ttaaatggaa ttacatttta
    52501 atttagaatt agtagaaacc tataaaagta atagccaaaa ggcacgtatc ttaacggagg
    52561 attgggttta tcgtcagtct tattgcccta attgtgggaa caatccctta aatcattttg
    52621 aaaataatcg gcctgtagca gatttttact gtaatcattg tagtgaggag tttgaactaa
    52681 agagcaaaaa aggaaatttt tcatcaacaa tcaatgatgg tgcttatgca acgatgatga
    52741 agcgtgtgca ggcagataat aatcctaatt tctttttttt aacttacaca aaaaattttg
    52801 aggtaaataa ctttcttgtc cttccgaagc aatttgttac accgaaatcg attattcaaa
    52861 gaaaaccact tgcaccaact gctagacgag caggttggat tggttgtgac attgatttat
    52921 cacaagtacc ttctaaagga aggatatttc ttgtgcaaga tggacaagtt agagatccag
    52981 aaaaagttac aaaagaattt aagcaaggtt tatttttaag gaagagctct ctgtcatcaa
    53041 gaggttggac aatagaaatt ctaaattgta tagataagat agagggttca gaatttaccc
    53101 ttgaagatat gtatcgtttt gaaagtgacc taaaaaatat ctttgttaag aacaatcata
    53161 tcaaagaaaa gattaggcaa cagcttcaaa tattaagaga caaagaaata atagaattta
    53221 aaggtagagg aaagtatcgg aaattatgaa aacgaaacaa cttgttgcat cagaagaggt
    53281 gtatgatttc ttaaaagtca tctggcctga ttatgaaact gaaagccgtt acgataacct
    53341 aagtttaatc gtctgtacct tatcagatcc cgattgtgtg agatggttat ctgaaaatat
    53401 gaaatttggt gacgaaaaac aactagcttt gatgaaggaa aaatatgggt gggaagtagg
    53461 agataaattg ccagagtggc tacatagctc ctatcataga ttattgttaa taggtgaatt
    53521 attggaaagc aatctaaaac tgaaaaagta tacagtagaa attacagaaa ctttatcacg
    53581 tttagtaagt atagaggctg aaaatccaga tgaagccgaa cgacttgtaa gagaaaagta
    53641 taagagttgt gaaattgttc ttgatgcaga tgattttcag gactatgaca ctagcatata
    53701 tgaataggta gatgttttta ttttgtcaac aaaaaagagg ctcgcacctc tttttcttat
    53761 ttctttttat gatttaatac ggcattgagg acaatagcga gtaggctggc tacgacgatt
    53821 ccgtttgaga agaacatttg gaaggctgtc ggcatgctga caaagagatt actgttgttg
    53881 agaccgacac ctgcagcgat tgaaacagct gcgataagga agttgtgttc attgttagca
    53941 aagtcaacac gggcgaggat ttgcatccct tgaattgata caaaaccaaa cattaccagc
    54001 atggcaccac cgaggacgga gcttggaatg atttgggcaa gggcgccaaa cttaggaagc
    54061 agtccaagga gaaccaggaa accagctgcg tagtagattg gcaggcgttt tttgatgcct
    54121 gacaatttaa ccaaaccaac gttttgtgaa aatccggtgt aagggaaggt gttaaagatt
    54181 cctccgagaa gtacggccaa accttctgcg cggtaaccgt tgcgaaggcg cgtgctgtcg
    54241 attggatctt ttgtgatatc agacaaggct agataaacac cagttgactc aaccatagac
    54301 accgttgcga taatacacat catgacaata gatgagattt caaaggttgg catcccaaag
    54361 tagagtggaa ttgggacatg gacaagtgga gctaccgcaa caggagagaa gtccaccaag
    54421 cccatagtag cagcaatggc agttccaaca accagaccaa tcaaaataga gatagacttg
    54481 ataaatcctt tggtaaagat gttgatcaag aggataatca gaacagtaat agctgcaagc
    54541 aagagacttt gaccagttgg ctctggaacg ttatttccca tatttccaat agcgacaggg
    54601 atcaaggtta aaccaatcgt ggtaataaca gatcctgtta cgatagatgg gaagagattg
    54661 gctatttttg agaagatgcc tgaaacaaga accacgtaaa tcccagatgc gataagggca
    54721 ccaaacatag cgccactacc atggctttgc ccaatcataa tcaagggagc gaccgactgg
    54781 aatgcaactc caagaacgac tgggagtcca atcccaaagt atttgttgag ttggagttgg
    54841 aggaaggttg ccaccccaca catgaagata tctgtagaaa tcaggtaggt caactgctca
    54901 gctgaatagc caagggctgt cgcaatcatg atgggaacca ggatagatcc tgagtacatg
    54961 gctagtaagt gctgcaagcc cagaacggct gcttgcgagt gtttttcttg agtttgcatt
    55021 agagatctgc ctccttaaat acgacctgac cattttcaaa acgatccaag cgagcaagtg
    55081 ataggacagg gtagcctgct ttttcaagca aatcacgacc atcttggaag gatttctcaa
    55141 tcacgatacc gatagcttgg actgtggcac cggcctgttc gatgatttga atcaagcctt
    55201 tagcagcttg gccattagca aggaaatcgt cgataatcaa aaccttgtcc tctggtgaga
    55261 ggaattttcc agcgatagaa acagtgctgg tcacctgctt ggtaaaggag tagacttgag
    55321 cagttaagat gccttcgttc atggtgatgt tcttagcttt tttggcgaaa atcatgggaa
    55381 cgtttaaggc ttcagctgta aaaacggctg gggcaatacc cgacgcttca atggttacga
    55441 ccttggtaat gccagtagca gcaaattttt ccgcaaaaac cttaccaatc tctcgcatca
    55501 agctaaagtc aacttggtgg gttaaaaagg aatctacctt gaggatgtta tcacccaaga
    55561 tatgcccatc cttgaggatg cgctcttcta ataatttcat aagacctcct aaagtctaaa
    55621 agttaattta cttgttgttt aaatatttct atagtgatcc cttttgctaa tactatatat
    55681 ttgataaaac tattacgagc gaagcgagtc ttatcaaata tttcccgttg tagtggtatc
    55741 atagacaata atcttgttat tgtctatgac gggatttttg agacttttgg ctcaaaaatt
    55801 agggatgaaa ttccctggat tcctgaaatt attcacagga taatttcacc tcccgtccgc
    55861 actaattaag ggaaatatta aaaatattca aaaaagacct acttaatctc taagtaagtc
    55921 ccccaaatag gcatggcaaa aacggccata tctcactgct gacttactta ttgttaggtg
    55981 ttccggcacc ttgtagaaac gtcgtgccaa ttcacgacat aaacaagtaa aacgatattc
    56041 aattttaaat aggcttgagc caatgttttt attttacact aaataacttt ataaatcaac
    56101 tattttgtta gtgttttggt ttaaaaaacg aacaaacaga agagagggtg aacaaaaact
    56161 ccattgtaag ctaatattta tactaaatga aaatcaaaga gcaaactagg aagctatcca
    56221 caacctcaaa acactgtttt gaggttgtgg atagaattga cagagtcagt atcatatacc
    56281 tacggtaagg cgacgttgac gtggcttgaa gagattttcg aagagtatta gaagattttt
    56341 ccatcataaa aggcatacta tcaagttttt aaacacctga caatatgcct ttttctaact
    56401 ttaaagactt ttcccaattt ttattattct actcgctaaa tcttaaaaaa tagccatttg
    56461 gatccaaaac tgcaaattta tgaggataga tatagggatc actgacacga aactttcttt
    56521 tggtcaagag gcgataaata ggatagtttg ccttcatcac tctttaatag agttttgaaa
    56581 catcctttat gccaaaggag agattgactc cacgaccaaa tggataggtc agttcagcta
    56641 gttgatcctt tgttccctcc tctaacatta gttgacactc ttcaagagaa agaaagagaa
    56701 agttttcttc tggacgttgg tattcaatcc taaaacccag taaaccacag tagaaggacc
    56761 gggactgttc gatattcgat acaagcaact cgggaatgac cgcattgtag tccatataga
    56821 aaattcttac aagtcaattt ccaagacaat cggtgtatgg tcttggcgag cacctgagtc
    56881 aatcatatca gatttagtga ccttgtcagc gatacggtta cttgtgagcc agtagtcgat
    56941 tctccagcct gtattgttga ttttagaagt tttgctgcgt tgtgcccacc aagtgtagcg
    57001 ttcaggaaca tcgccatgaa catggcggaa ggtgtctgta aatccagttg ccaaaaggtt
    57061 ggtaaatcca gcacgttcct cgtcagtaaa tccaggtgaa cggcggttgc tagcaggatt
    57121 tgcaaggtcg atttcattgt gggctacgtt gtagtcaccg gtcgcaagga ctggtttttc
    57181 tttgtctagt tcagccaaat actcagcata tttaacatcc cagacttggc gttcttccaa
    57241 gcgtttgaga ccgtcaccag cgtttggagt gtaaacttgg gttacgaaaa atgcatcaaa
    57301 ttctagagtg atgatacggc cttccaagtc catggtagaa ggggcaccga tttctgggaa
    57361 gctgatagta ggtgtaagtt cttttttata aaggaacatg gttccagcat agcctttacg
    57421 ggcaggctct tgggaagaac gccacgtgtt ttcgtagcct gggaagagtt cttctaaaat
    57481 ttctaagtgt ttctttgtag gtcctttggc agaaagcttg gtttcttgga tagcaatgat
    57541 atcagcattt tcagcgacca aggtttgtag gacttcttgg gacaatttgg cacgagctga
    57601 gtcactagtt agggcagcgt ttagggaatc aatattccat gagataagtt tcataaagtt
    57661 acctttttca ttcagattat agattttatt ataccaaaaa aagatctatt tccccaacgt
    57721 atggtttgaa aaattactct ctttcgttta taattaagaa tgattttatg aaagggagtg
    57781 aaaatatatg aaattctact cttatgacta tgtactcagc caaatcggtc agcaaaatgg
    57841 tatcatggtt ggctttggga ttgttctatt agctgtgaca gttttttttg ctttcaaggc
    57901 ataccatgat aaaaagggaa ccgaatttcg tgagttggtc atgatttcag ctctggcctt
    57961 atttagctct gcttttggtc agcatcacga cttatcaaaa caatcaagtt tctaacaata
    58021 aatttcaaac ttcacttcat ttcatcgagg ttgtttccaa agatttggga gtagacaagt
    58081 cagaagtcta tgttaatact tccacaaaca cagatggcgc acttatcaag gtgggagatc
    58141 gctattatcg tgccctaaac ggaagtgagc cagacaagta cctgttagag aaagtcgaat
    58201 tgtataagac agacgcaatt gaactggtgg atgtgaacaa atgacactta attatatcga
    58261 aattttaatc aaactggtct tgactctcaa atggctcaac aacaatgttc actttgtgaa
    58321 acgtttgatt gatggtaagc caactctcct tatcaaaaat gggaatattg acccagaagc
    58381 ctgtcgttca gttggtttgt ctgcatcgga tgtagccctc aaacttcgta gccaagggat
    58441 tttccagatg aagcaagtca aacgagctgt gcaagagcaa aatgggcaac ttatcgttgt
    58501 gcaaatggga gatgaaaatc ctaagtatcc agttgtgact gacggtgtga ttcaagtaga
    58561 tgtcttggaa tcgattggtc gtagcgaaga gtggttgctt gataacctca gtaaacaagg
    58621 gcatgacaat gtagccaata tctttattgc tgaatatgac aagggtgctg ttacagtcgt
    58681 aacttatgaa taagaaaaac ctggggtctt gtactcttcg aaaatctctt caaaccgcgt
    58741 caacgtcgcc ttgccgtatg taggttactg acttcgtcag ttctatctac aacctcaaag
    58801 cagtgctttg agcagcctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat
    58861 tggcctcagg tttccatttg caatcagaaa gggattttat gtccattatt caaaaactct
    58921 ggtggttttt caagttagaa aaacgccgtt atctagtcgg gattgtggcc ctggtcttgg
    58981 tttccgtcct caatctcatt cctcctatgg ttatggggcg agtcattgat gccatcacat
    59041 cggggcaatt aactcagcag gacctccttc ttagcctatt ttacttgcta cttgcagcct
    59101 ttggtatgta ctatttgcgc tatgtgtggc gtatgtatat ccttgggacc tcttattgct
    59161 tgggacagat catgcggtct cgcttgttta agcatttcac aaaaatgtcg tcagcctttt
    59221 atcaaaccta tcggacgggt gatctgatgg cacacgcaac caatgatatc aatgccttga
    59281 ctcgtttagc aggtggcggt gtcatgtctg cggtggatgc ctctatcacg gctctggtga
    59341 ctttgttgac catgctcttt agcatctcat ggcagatgac tcttgttgcc attctccccc
    59401 tacctttcat ggcctatacg actagtcgcc tagggagaaa gactcataag gcctttggcg
    59461 aatcccaagc tgctttttct gaactcaata acaaggtaca ggagtccgta tcaggtatca
    59521 aagtgaccaa gtctttcggt tatcaggcag acgagttgaa gtcttttcag gcagtcaatg
    59581 aattaacctt ccaaaagaac ctgcaaacca tgaaatatga tagtctcttt gaccctatgg
    59641 ttctcttgtt tgttggttcg tcctatgttt taacgctttt ggttggctcc ttgatggttc
    59701 aggaagggca gattacagtt gggaatctag tcacctttat cagctatttg gatatgctgg
    59761 tctggcctct tctggccatc ggtttcctct ttaatactac tcagcgaggg aaggtttctt
    59821 accagcggat tgaaaatctt ttgtctcagg aatctcctgt acaagaccct gagtttcctc
    59881 tggatggtat tgaaaatggg cgtttggagt atgccattga cagctttgct tttgaaaatg
    59941 aggaaacact gacggatatt cactttagtt tggcaaaagg gcaaacactg ggcttggttg
    60001 ggcagacagg ctctgggaaa acgtccttaa tcaagctcct cttgcgtgaa tacgatgtgg
    60061 ataagggtac tatttatcta aacggtcacg atattcggga ctatcgtctg acagaccttc
    60121 gcagtctcat gggctatgtt cctcaggacc agtttctctt tgcgacttca atcctagaca
    60181 atatccgctt tggcaatcct aacttgcccc tttcagcggt cgaggaagct actaagctag
    60241 cccgagttta ccaagatatt gtagacatgc ctcaaggatt tgatacgctg attggtgaaa
    60301 aaggagtcag tctttctggt ggtcaaaagc aacggttggc tatgagtcgg gctatgattt
    60361 tagaccctga tatcttgatt ttggatgatt ccttatccgc cgtagatgcc aagacagagt
    60421 atgcgattat cgacaacctc aaggagacgc gaaaggacaa gacaaccatt atcactgccc
    60481 atcgcctgag tgcagttgtc catgcagatt tgattttagt cctgcaaaat ggtcaaatta
    60541 tcgaacgagg caggcacgaa gacttgctag ctttggatgg ctggtatgcc caaacctacc
    60601 agtctcagca gctggaaatg aagggagaag aagatgcaga ataaacaaga acaatggact
    60661 gtattgaagc gcttgatgtc ctatctcaag ccttatggac tccttacctt tttggcactc
    60721 agttttctcc tagcgacgac ggtcattaaa agtgtcattc cccttgtggc ttcccacttt
    60781 atcgaccagt atctcagcaa tcttaaccaa ctagccgtga ccgttttgct ggtctactat
    60841 ggtctctaca tcctacaaac tgtagttcag tatgtcggca atcttctctt tgcgcgcgtg
    60901 tcttacagta ttgttaggga tattcgtcgg gatgcctttg ccaatatgga gaaactgggc
    60961 atgtcttact ttgacaagac gccagcaggt tctatcgttt ctcgtttgac caacgatacc
    61021 gagacgatta gtgatatgtt ttctgggatt ttatccagct ttatctcagc agtttttatc
    61081 tttctgacaa ccctttatac catgttggtg ctggattttc gtttgacagc attagtcttg
    61141 ctctttcttc ctttgatttt ccttttggtc aatctctatc gaaaaaagtc agtgaaaatc
    61201 atcgagaaaa ccagaagtct cttgtcagat atcaatagta agctggcaga gaatatcgag
    61261 ggaatcagga ttattcaggc ctttaatcaa gagaagcgcc tgcaggcaga atttgatgaa
    61321 atcaaccaag agcacttggc ctatgccaac cgttctgtag ccttggatgc cctctttttg
    61381 agacctgcca tgagtttgtt gaaacttcta ggttatgctg tcttgatgac ctattttggc
    61441 tatcgtggtc tttctatcgg gataacggcc gggaccatgt atgcttttat ccagtacatc
    61501 aaccgcctct ttgacccttt gattgaggtg acgcaaaact tttcaacact gcaaacgtct
    61561 atggtttctg caggccgtgt ctttgcctta atcgatgaga ggacctatga gccccttcaa
    61621 gaaaatgggc aagccaaagt caaagaaggc aatatccgtt ttgaacatgt gtgtttctcg
    61681 tatgacggta aacatccgat tctggatgac atttctttct ctgttaataa gggtgaaacc
    61741 attgcctttg taggtcatac aggttcaggg aaatcgtcta ttatcaatgt cctcatgcgc
    61801 ttttatgaat tccagtcagg gagagttctc ttggatgatg tggatatcag ggatttcagt
    61861 caagaagagc tgagaaaaaa catcggtttg gttttacagg aacccttcct ctatcatgga
    61921 actattaagt ccaatatcgc catgtaccaa gaaatcagtg atgagcaggt tcaggctgcg
    61981 gcagcctttg tggatgcaga ttcctttatt caagaacttc ctcaggggta cgactcccct
    62041 gtttccgagc gtggttcgag cttctctact gggcagcgcc agcttcttgc ctttgctaga
    62101 acagtcgcca gccagcctaa aatcctgatt ttggatgaag cgacagccaa tattgactct
    62161 gaaacagaaa gtttggttca agcttctctg gcgaagatga gacagggccg aacaactatt
    62221 gctatcgctc accgcctttc tactattcaa gacgccaact gcatctatgt cttggataag
    62281 ggacgcatta tcgagagtgg aacccatgag gaactcttga ctctgggagg aacctatcac
    62341 aagatgtata gtttgcaggc aggggccatg gccgatactc tttgaaaatc tctttaaacc
    62401 atgtcagctt tatctgcaat ctcaaagctg tactttgatt ttcattgagt actagaagga
    62461 aatccttcaa attacagatt tctttcaccg ccttttccat tttgtggtat aatgaaaaat
    62521 gttgacaaat agtataataa aaacaaagga gaacagcatg ctgaaatggg aagacttgcc
    62581 tgtggaaatg aaatcaagcg aggttgagtc ttactaccag cttgtctcta aaaggaaggg
    62641 ttcgctgatt ttcaagcgtt gcttggactg ggttttggcc ttggtcttac tggttctaac
    62701 ttctcccatc tttctcatct tgagcatttg gatcaagttg gatagcaagg ggccagtgat
    62761 ttacaagcaa gagcgtgtga cccagtacaa ccgtcggttc aagatttgga agttccgtac
    62821 catggtgacg gatgcggata aaaaaggaag tctggtgact tctgctaacg atagccgtat
    62881 taccaaggtt ggaaatttca tccgacgtgt ccgtttggac gaactgcctc agttggtcaa
    62941 tgtccttaaa ggtgagatgt cctttgtcgg tacacgacct gaagtgccac gttatacaga
    63001 gcagtatagc cctgaaatga tggcaacctt gctcttgcaa gcaggaatta cctctccagc
    63061 cagcatcaac tacaaggatg aggacaccat catcagtcaa atgacggaga aaggtctgtc
    63121 agttgatcag gcctatgtgg agcatgttct tcctgaaaag atgcgctata acctcgccta
    63181 tctccgagag tttagtttct ttggggacat caaaatcatg tttcaaaccg tgtttgaggt
    63241 actaaaataa agtagtcata agaaaatgag tacagataaa aggagcaaat caatgccaaa
    63301 ttacaatatt ccattttcac cgcctgatat cacagaagca gaaattgctg aagtagcgga
    63361 taccctgcgt tctggttgga tcacaacagg tcctaaaaca aaagaactgg agcgccgctt
    63421 gtctctttac acacagacac ctaagactgt ttgtctcaac tctgcgacag ccgctctgga
    63481 gttgatttta cgcgttttgg aagtgggacc tggtgatgaa gtcatcgttc cagccatgac
    63541 ctatacggct tcatgtagtg tcattacgca cgtgggagca acccctgtca tggtggatat
    63601 ccaagcagat acgtttgaga tggactatga cctgcttgag caagctatca ctgagaaaac
    63661 taaggtgatt atcccagtag agctcgcagg gattgtttgc gattatgacc gtttgttcca
    63721 agtcgtggag aaaaaacgtg acttctttac cgcttcaagc aagtggcaaa aggcctttaa
    63781 ccgtattgtc attgtctctg atagtgccca cgctttggga tctacttata aaggacaacc
    63841 ttctggttct atcgctgatt ttacttcctt ctcattccat gccgttaaga actttacaac
    63901 ggcagaaggt ggaagtgcga cttggaaagc caatccagtg attgatgacg aagagatgta
    63961 caaggaattc caaatccttt cccttcacgg gcaaactaag gatgctcttg ccaagatgca
    64021 actggggtca tgggaatacg atatcgttac accagcctat aagtgcaaca tgaccgatat
    64081 catggcttca cttggtttgg tacaattgga ccgctatcca agtttgttgc aacgtcgtaa
    64141 ggacattgtg gaccgctatg atagtggttt tgcaggttct cgcatccatc ctttggcaca
    64201 caagactgaa actgtcgaat cttcacgcca cctctacatc acccgtgtag aaggagcaag
    64261 cctagaagaa cgcaacctca tcatccaaga attggctaaa gcaggaattg caagtaatgt
    64321 tcactacaaa ccgcttcctc tcttgacagc ctataagaat cttggatttg atatgacgaa
    64381 ctatcctaag gcctatgcct tctttgagaa tgaaattacc ctccctcttc atactaaatt
    64441 aagcgatgaa gaagtagact atatcattga gactttcaaa acagtttctg aaaaagtgct
    64501 aactttatca aaaaaatgac aaactacagt caagcgaaag tgatcctgtc cctaaaaagt
    64561 ctaattgagt gtaaaaactg ttgttttcaa ttgataatag tttacacctg tagttgaggc
    64621 ctctttctcc tcagagagag aatttttata ggattttcct ttcttgtggg agtcccgtgg
    64681 tttgaaataa gatgtgagca atttggtgta gcatttagaa tccttactag acatcattta
    64741 gaaaatctag tgtcttgttc tagttttcaa ttcaccctat tttttgaaag acgtgagttt
    64801 ccatgagtga gattgtggaa actcgcgtct ttttttgttt tcagaatatt gttcaaagtt
    64861 ttgtgcctgt ctttcatgtt ctagtcattc ttttgcatga tagaatttat agcatgttga
    64921 tattataata atacgaatat cccatatgtt tagtgatgct tgctatacat cattagatct
    64981 cctgcgagac aatctataaa acacttgtct acgattacct atatgcccta ttccagtatt
    65041 ttagaagcac tgcatctatt tttatcgagg ttaaatctag cttttataga aggtctattt
    65101 aagaaatata ttgtagtgtt ttagtttcaa tccgccatat gagcgatatt caggtaaata
    65161 tccctggcga atgcttgtat gacaaggtat ttgttctttc atttataatt tacaacatat
    65221 caataaattt aaatatagta aatgggatat tttatattca agctaagaaa gatagcatca
    65281 cttttgaatg gaaggctaaa gagcaaacta ggaagttggc catagatagc tcaaaaccct
    65341 gctttgaggt tgtagatata gtaaaatgaa ataagaatag gacaaattga tcgggacagt
    65401 taaatcgatt tctaacaatg ttttagaagt agaggtgtac tattatagtt tcagtctact
    65461 atagaactga ccaagtcagt aacctagact tagggcaagg cggcactgac ctagtttgaa
    65521 gagatttccg aagagtataa attttaatat tttcttgtgt tattccttga caattcaatt
    65581 tggaaaatat atgataaaga taatgacagc ggtgtcattc tatctatttt aagaaaagta
    65641 ataatcaatt gttaaaaata gtaaaaaaat tggaggttct gatgaaatat tttgttccta
    65701 atgaggtatt cagtattcgt aaattaaagg tggggacttg ctcggtacta ttggcaattt
    65761 caattttggg aagccaaggt attttatcgg atgaagttgt tactagttct tcaccgatgg
    65821 ctacaaaaga gtcttctaat gcaattacta atgatttaga taattcacca actgttaatc
    65881 agaatcgttc tgctgaaatg attgcctcta attcaaccac taatggttta gataattcgt
    65941 taagtgttaa tagtatcagc tctaatggta ctattcgttc caattcacaa ttagacaaca
    66001 gaacagttga atctacagta acatctacta atgaaaataa gagttataag gaagatgtta
    66061 taagtgacag aattatcaaa aaagaatttg aagatactgc tttaagtgta aaagattatg
    66121 gtgcggtagg tgatgggatt catgatgatc gacaagcaat tcaagatgca atagatgctg
    66181 cagctcaagg gctaggtgga ggaaatgtat attttcctga aggaacttat ttagtaaaag
    66241 aaattgtttt tttaaaaagt catacacact tagaattgaa tgagaaagct acaattctaa
    66301 atggtataaa tattaagaat cacccttcca ttgtttttat gacaggttta tttacggatg
    66361 atggtgcgca agtagaatgg ggcccaacag aagatattag ttattctggt ggtacgattg
    66421 atatgaacgg tgctttgaat gaagaaggaa ctaaagcaaa aaatctacca cttataaatt
    66481 cttcaggtgc atttgctatt gggaattcaa ataacgtaac tataaaaaat gtaacattca
    66541 aggatagtta tcaagggcat gctattcaaa ttgcaggttc gaaaaatgta ttagttgata
    66601 attctcgttt tcttgggcaa gccttaccca aaacgatgaa ggatgggcaa atcataagta
    66661 aggagagcat tcagattgaa ccattaacta gaaaaggttt tccttatgcc ttgaatgatg
    66721 atgggaaaaa atctgaaaat gtgactattc aaaattccta ttttggcaaa agtgataaat
    66781 ctggggaatt agtaacagca attggcacac actatcaaac attgtcgaca cagaacccct
    66841 ctaatattaa aattttaaat aatcattttg ataacatgat gtatgcaggt gtacgtttta
    66901 caggattcac tgatgtatta atcaaaggaa atcgctttga taagaaagtt aaaggagaga
    66961 gtgtacatta tcgagaaagc ggagcagctt tagtaaatgc ttatagctat aaaaacacta
    67021 aagacctatt agatttaaat aaacaggtgg ttatcgctga aaatatattt aatattgccg
    67081 atcctaaaac aaaagcgata cgagttgcaa aagatagtgc agaatattta ggaaaagtat
    67141 cagatattac tgtaacaaaa aatgtaatta ataataattc taaggaaaca gaacaaccaa
    67201 atattgaatt attacgagtt agtgataatt tagtagtctc agagaatagt atattcgggg
    67261 gtaaagaagg aattgttatt gaggattcaa agggtaaaat aaccgtttta aataaccaat
    67321 tttataattt atccggtaag tatatatcat tcatcaaatc taatgcaaat gggaaagaac
    67381 ctgttatacg tgatagcgat ggtaatttca atattgtaac ggagaatggg ctttacaaaa
    67441 ttgtaacaaa taatttaagt gataaaaacg aaaaagaaaa aaacaaagag gaaaaacaat
    67501 ctaattcaaa taatgtaatt gatagtaacc agaagaacgg agagtttaac tcaagtaaag
    67561 ataatagaca aatgaatgac aagatcgaca ataaacaaga taataagaca gaagaagtaa
    67621 actataaaat agttggatat ggcagagaaa ctgaaaatca tattaataaa tctaaagaaa
    67681 tagtagatgt aaaacaaaaa ttaccaaaga ctggttcgaa taagattatg gaactattct
    67741 taacagtgac aggaattggt ttacttttga cactaaaagg gttgaagtat tatggtaaag
    67801 ataaataaaa tttgttcgat acaaggaagt tccgtagaaa atgaggatat tgtaggttca
    67861 caaaatcagt atttttggat tattggtgga gctacagatt tatataattc taaagaggag
    67921 ataggttatt cagtctcaga agttgtacat attttatcag aaagtttgtc ggttaattgt
    67981 aaagaatcaa aaactcttaa acaaatattt gaaactgctt tactcgaggt taaagatgaa
    68041 atcggtttaa actcatatga attaacagag tatagtaaaa tgaaataata ataggacaaa
    68101 tc
//
LOCUS       DAVKAU010000004        66573 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVKAU010000004 DAVKAU010000000
VERSION     DAVKAU010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.004"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            24..2054
                     /locus_tag="VWX48_000297"
     CDS             24..2054
                     /locus_tag="VWX48_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9170996.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKVSSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            2058..2342
                     /locus_tag="VWX48_000298"
     CDS             2058..2342
                     /locus_tag="VWX48_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9170997.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKICEEKGLI"
     gene            2355..3701
                     /locus_tag="VWX48_000299"
     CDS             2355..3701
                     /locus_tag="VWX48_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9170998.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            3705..4562
                     /locus_tag="VWX48_000300"
     CDS             3705..4562
                     /locus_tag="VWX48_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9170999.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            4559..5491
                     /locus_tag="VWX48_000301"
     CDS             4559..5491
                     /locus_tag="VWX48_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU9171000.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            5724..7427
                     /gene="ilvD"
                     /locus_tag="VWX48_000302"
     CDS             5724..7427
                     /gene="ilvD"
                     /locus_tag="VWX48_000302"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU9171001.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(7588..7668)
                     /locus_tag="VWX48_000303"
                     /pseudo
     CDS             complement(7588..7668)
                     /locus_tag="VWX48_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(7726..8067)
                     /locus_tag="VWX48_000304"
     CDS             complement(7726..8067)
                     /locus_tag="VWX48_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9171002.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            8191..9042
                     /gene="rgg"
                     /locus_tag="VWX48_000305"
     CDS             8191..9042
                     /gene="rgg"
                     /locus_tag="VWX48_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU9171003.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSAFLSVSLFTRYVREMVRKSDFLMEMSGNRNFFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            9235..10482
                     /locus_tag="VWX48_000306"
     CDS             9235..10482
                     /locus_tag="VWX48_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU9171004.1"
                     /translation="MKLLFRNPAYRILTLSCFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            10560..11849
                     /locus_tag="VWX48_000307"
     CDS             10560..11849
                     /locus_tag="VWX48_000307"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU9171005.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            11846..11923
                     /locus_tag="VWX48_000308"
                     /pseudo
     CDS             11846..11923
                     /locus_tag="VWX48_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            12190..12504
                     /locus_tag="VWX48_000309"
     CDS             12190..12504
                     /locus_tag="VWX48_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171006.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            12514..12720
                     /locus_tag="VWX48_000310"
     CDS             12514..12720
                     /locus_tag="VWX48_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9171007.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            12720..12917
                     /locus_tag="VWX48_000311"
     CDS             12720..12917
                     /locus_tag="VWX48_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171008.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            12920..13654
                     /locus_tag="VWX48_000312"
     CDS             12920..13654
                     /locus_tag="VWX48_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU9171009.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            13666..14307
                     /locus_tag="VWX48_000313"
     CDS             13666..14307
                     /locus_tag="VWX48_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9171010.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            14325..14555
                     /locus_tag="VWX48_000314"
     CDS             14325..14555
                     /locus_tag="VWX48_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171011.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            14591..14671
                     /locus_tag="VWX48_000315"
                     /pseudo
     CDS             14591..14671
                     /locus_tag="VWX48_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14907..16670
                     /gene="aspS"
                     /locus_tag="VWX48_000316"
     CDS             14907..16670
                     /gene="aspS"
                     /locus_tag="VWX48_000316"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU9171012.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPHMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            16648..17589
                     /locus_tag="VWX48_000317"
     CDS             16648..17589
                     /locus_tag="VWX48_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9171013.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(17709..17789)
                     /locus_tag="VWX48_000318"
                     /pseudo
     CDS             complement(17709..17789)
                     /locus_tag="VWX48_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(17925..18911)
                     /locus_tag="VWX48_000319"
     CDS             complement(17925..18911)
                     /locus_tag="VWX48_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9171014.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(18921..19721)
                     /locus_tag="VWX48_000320"
     CDS             complement(18921..19721)
                     /locus_tag="VWX48_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU9171015.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(19982..20824)
                     /locus_tag="VWX48_000321"
     CDS             complement(19982..20824)
                     /locus_tag="VWX48_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9171016.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(20826..22118)
                     /locus_tag="VWX48_000322"
     CDS             complement(20826..22118)
                     /locus_tag="VWX48_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9171017.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLSVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(22229..23500)
                     /locus_tag="VWX48_000323"
     CDS             complement(22229..23500)
                     /locus_tag="VWX48_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9171018.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            24050..25567
                     /gene="malQ"
                     /locus_tag="VWX48_000324"
     CDS             24050..25567
                     /gene="malQ"
                     /locus_tag="VWX48_000324"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU9171019.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEDL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            25593..27851
                     /gene="glgP"
                     /locus_tag="VWX48_000325"
     CDS             25593..27851
                     /gene="glgP"
                     /locus_tag="VWX48_000325"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU9171020.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(28895..29467)
                     /locus_tag="VWX48_000326"
     CDS             complement(28895..29467)
                     /locus_tag="VWX48_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171021.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLVSWFVNDVALE
                     FAMNLLSSGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(30266..31114)
                     /locus_tag="VWX48_000327"
     CDS             complement(30266..31114)
                     /locus_tag="VWX48_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9171022.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDDN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSKLTEITIEAEI
                     LVGKAF"
     gene            31266..31544
                     /locus_tag="VWX48_000328"
     CDS             31266..31544
                     /locus_tag="VWX48_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171023.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            31546..33609
                     /locus_tag="VWX48_000329"
     CDS             31546..33609
                     /locus_tag="VWX48_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9171024.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESYPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(33687..34943)
                     /locus_tag="VWX48_000330"
     CDS             complement(33687..34943)
                     /locus_tag="VWX48_000330"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU9171025.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            35085..37550
                     /locus_tag="VWX48_000331"
     CDS             35085..37550
                     /locus_tag="VWX48_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9171026.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKAGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            37615..38526
                     /locus_tag="VWX48_000332"
     CDS             37615..38526
                     /locus_tag="VWX48_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU9171027.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            38756..39454
                     /gene="dapD"
                     /locus_tag="VWX48_000333"
     CDS             38756..39454
                     /gene="dapD"
                     /locus_tag="VWX48_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU9171028.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            39522..40652
                     /locus_tag="VWX48_000334"
     CDS             39522..40652
                     /locus_tag="VWX48_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU9171029.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEAVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            40664..41203
                     /locus_tag="VWX48_000335"
     CDS             40664..41203
                     /locus_tag="VWX48_000335"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU9171030.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKRVLTPKTYPKGRMDFVVYDPQQLVKTSFGLLEPQ
                     GDLEVVDVSKIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            41187..41864
                     /locus_tag="VWX48_000336"
     CDS             41187..41864
                     /locus_tag="VWX48_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU9171031.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(41931..42830)
                     /gene="galU"
                     /locus_tag="VWX48_000337"
     CDS             complement(41931..42830)
                     /gene="galU"
                     /locus_tag="VWX48_000337"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU9171032.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQGEGSNGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(42852..43868)
                     /locus_tag="VWX48_000338"
     CDS             complement(42852..43868)
                     /locus_tag="VWX48_000338"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9171033.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRSAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            44080..44461
                     /locus_tag="VWX48_000339"
                     /pseudo
     CDS             44080..44461
                     /locus_tag="VWX48_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(44634..45059)
                     /locus_tag="VWX48_000340"
     CDS             complement(44634..45059)
                     /locus_tag="VWX48_000340"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9171034.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEIRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(45127..45777)
                     /gene="phoU"
                     /locus_tag="VWX48_000341"
     CDS             complement(45127..45777)
                     /gene="phoU"
                     /locus_tag="VWX48_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9171035.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAKL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPGEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(45792..46544)
                     /gene="pstB"
                     /locus_tag="VWX48_000342"
     CDS             complement(45792..46544)
                     /gene="pstB"
                     /locus_tag="VWX48_000342"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9171036.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(46546..47361)
                     /gene="pstA"
                     /locus_tag="VWX48_000343"
     CDS             complement(46546..47361)
                     /gene="pstA"
                     /locus_tag="VWX48_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9171037.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(47354..48217)
                     /gene="pstC"
                     /locus_tag="VWX48_000344"
     CDS             complement(47354..48217)
                     /gene="pstC"
                     /locus_tag="VWX48_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9171038.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYSFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(48335..49210)
                     /locus_tag="VWX48_000345"
     CDS             complement(48335..49210)
                     /locus_tag="VWX48_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU9171039.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(49377..50708)
                     /locus_tag="VWX48_000346"
     CDS             complement(49377..50708)
                     /locus_tag="VWX48_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU9171040.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAKYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(50709..51416)
                     /locus_tag="VWX48_000347"
     CDS             complement(50709..51416)
                     /locus_tag="VWX48_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9171041.1"
                     /translation="MTKQVLLVDDEEHILRLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGIKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(51500..51985)
                     /locus_tag="VWX48_000348"
     CDS             complement(51500..51985)
                     /locus_tag="VWX48_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU9171042.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERADLLATYPEHKEMIEHLTR
                     Y"
     gene            51971..52528
                     /locus_tag="VWX48_000349"
                     /pseudo
     CDS             51971..52528
                     /locus_tag="VWX48_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(52918..54609)
                     /locus_tag="VWX48_000350"
     CDS             complement(52918..54609)
                     /locus_tag="VWX48_000350"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU9171043.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            54745..55191
                     /gene="argR"
                     /locus_tag="VWX48_000351"
     CDS             54745..55191
                     /gene="argR"
                     /locus_tag="VWX48_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9171044.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            55242..57776
                     /gene="mutS"
                     /locus_tag="VWX48_000352"
     CDS             55242..57776
                     /gene="mutS"
                     /locus_tag="VWX48_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU9171045.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREESA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQYLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            57923..59617
                     /gene="patA"
                     /locus_tag="VWX48_000353"
     CDS             57923..59617
                     /gene="patA"
                     /locus_tag="VWX48_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU9171046.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(59935..60198)
                     /locus_tag="VWX48_000354"
                     /pseudo
     CDS             complement(59935..60198)
                     /locus_tag="VWX48_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            60392..62158
                     /gene="patB"
                     /locus_tag="VWX48_000355"
     CDS             60392..62158
                     /gene="patB"
                     /locus_tag="VWX48_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU9171047.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            62297..62986
                     /locus_tag="VWX48_000356"
     CDS             62297..62986
                     /locus_tag="VWX48_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9171048.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            62990..63169
                     /locus_tag="VWX48_000357"
     CDS             62990..63169
                     /locus_tag="VWX48_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171049.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTRKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            63156..64505
                     /locus_tag="VWX48_000358"
     CDS             63156..64505
                     /locus_tag="VWX48_000358"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU9171050.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDKKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            64629..66089
                     /locus_tag="VWX48_000359"
     CDS             64629..66089
                     /locus_tag="VWX48_000359"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU9171051.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            66103..66537
                     /locus_tag="VWX48_000360"
     CDS             66103..66537
                     /locus_tag="VWX48_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9171052.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGKERASKFNER"
BASE COUNT        19557 a        12349 c        14458 g        20209 t
ORIGIN      
        1 attgtagtta gaaaggaaga gaaatgtttg attatagagc actagttatt ttgatgactt
       61 tgatggatca ttgtgagcta tcattatatg aattatctgt taaggtgagc ttacctataa
      121 aggaagtcaa agaaggaata gattatttag tgccttatct agctaataaa gggatagtgc
      181 tggataaaaa acaaggtcgc tatagtttat caaatcgtac gaagcagtct ttgacagata
      241 ttattaagtc ggatgaattg gttttaccaa agtcgactcg cttagcttta atctatcttt
      301 acactttttg ccgattagat tttatatcga ataatcatta ccaagacttt ttgaaagtaa
      361 gtaagaatac aaccttatct gatattcaat cattaagaaa gattatgtta gataatgatt
      421 tggagctagg gtacagtaga gcaaaaggtt atactttaca cggttcagag tggaataagc
      481 accgcttagc ttttcaaatg gttagtgagt tgctggaatc ctccataggg atttggggtt
      541 tggattatgt tttatccagt tgggggtatt cattaactta tgatttgata aatcaggtag
      601 ttaaagatta ttatgagaag ctacagctag tacctattgt taatcaatta aaagtttacc
      661 ttttcggttt agtattcatt ctgtgtaggt atcaaaggga tgttgaaaga gtatgtcttt
      721 cagagacatt agtatctcct gttattcaag atataaccac tattttattg gatacagtgg
      781 ttgatttggg aattatagat acggtgtttt ctgaggatga ttatcgctat atcacagttt
      841 tattatcaag ttgctttgaa ggtgaagtag atgttgctcc ggtttacttt aatcaattaa
      901 cagaggctat tataagtaga atggaagata tttctttgtt acattttaaa caaagggaag
      961 gattgagaga aaatcttcgc cgccacctta taccggctta ctatagatta aagttcggcc
     1021 tacctagttc aaatgaatat gtattgcatg ttaaagaaca ttatcctgat ttatttgaat
     1081 tagtcaaaga ttctttgatg cccttgatgg acgctattga caatcccata cctgatagtg
     1141 aaacagcata ttttgttatc catttcggag gttatttaaa gaaagcagat actttgcctc
     1201 aaaaatgcta taaagcagca atcatttgtc ctaatggtgt tagttcttca ttgatgttaa
     1261 aagagaatct attagcatta tttcctcaaa ttgagtttat aggaacctca aagattgatg
     1321 atttacaggt gaaagttagt agtgactatg atatggtttt ttctaccata aaggtggaga
     1381 cagaaaagcc aaattatcta gtttcggtta tgatgactga agagcaagca atacaactag
     1441 tagaactagt gttaaaagat tttccgaatt tagagtatgg agattttgag attgaacaaa
     1501 tcctgaatat tgtcaaaaga tatggaatta ttacacaaga attggaatta agattggcgt
     1561 taaagaatta tctttatcaa aaaaatgata gaaaggaaat tgtaccagtg ctagaacaac
     1621 ttattaccaa agaaacctat caggttagtt cgcaaaaatt aggatggaag gaggcgattc
     1681 gtttagcagc taaaccgctt ttggatcaag ataagataac tgagaactac cctgaggcaa
     1741 tgattcaaaa agtagaagag tttggacctt ttattaattt agggaaggga gtagcaattc
     1801 ctcacgctcg gccagatgaa ggtgtgaatg aaataggaat gtcaatgtta gttttggaag
     1861 aaccgattta tttattggat aatccagaac aagaggtaag attgttgatt tgtattgcag
     1921 ccattgataa tgagagtcat ttaaaggctt tgtcacattt aacaacaatt ttaagagata
     1981 aaaatcatgt tcaaacttta atatcatcaa aaaactataa tgatattaaa atgataatta
     2041 aacaggagga ttagataatg ttaaaaattg gtacagcttg tggttcagga ttaggttcaa
     2101 gttttatggt acagatgaat attgaatctg tattgagtga tttgaatgtt tcggatgtag
     2161 aagttgaaca ttatgattta ggtggagcag atccaaatgc agctgatatt tggattgttg
     2221 gtcgtgatct agctgattca gctagtcatc ttggagatgt tcgtatctta aatagtatta
     2281 ttgatatgga cgaactacga gaattaatta ctaaaatttg tgaagaaaaa ggacttatat
     2341 aggaggctag cgtcatgatg aagttcatat tggatattgt tagtacacca gctattttag
     2401 tagctttaat tgcaatctta ggattagttc ttcagaagaa gaaattacct gatattatta
     2461 aaggtggaat taagaccttt gttggtttct tagttgtatc tggtggtgca ggaattgtac
     2521 aaaattcttt aaatccattt ggtaccatgt ttgagcatgc ttttcattta tctggcgttg
     2581 tgccgaataa tgaagcaatt gtagctgtag ctttaacaac atatggctca gctactgcaa
     2641 tgattatgtt tgcaggcatg gtgttcaata tcttaatcgc tcgttttact cgatttaaat
     2701 atattttttt aacagggcac cacactctat atatggcatg tatgattgcg gtcattttat
     2761 cagttgctgg ctttactagc ttgcctctca tcttactagg aggattagca ctcggtatta
     2821 ttatgagtat ttccccagca tttgttcaaa aatatatggt tcaattaact ggaaatgaca
     2881 aggtggcttt aggtcatttc agttctttgg gatattggtt gagtggtttt actggtagcc
     2941 ttatcggtga caaatcaaaa tcaacagagg acattaaatt tccaaagagt ttagcttttt
     3001 tacgtgatag tactgttagt attactttat ccatggcagt tatttacatt attgtagcta
     3061 tctttgcagg gtcagaatat atagaaaaag aaatcagtag tggtacaagt ggtctagttt
     3121 atgctttaca attagcaggt caatttgcag caggggtatt tgttatttta gcaggtgttc
     3181 gccttatttt gggcgaaatt gttccagcct ttaaaggtat ttcagagcgt cttgtaccta
     3241 attccaaacc tgctttggat tgtccgattg tttatactta tgcacccaat gcagttctaa
     3301 ttggatttat ctctagtttt gttggtggtt tagtaagtat ggtaattatg attgcttcag
     3361 gaacggttgt tatcttacca ggcgttgtac ctcatttctt ctgtggagcg actgcaggtg
     3421 tcattgggaa tgcatctggt ggtgttcgtg gagccactat tggagcattt ttacaaggta
     3481 ttttaatcag ttttcttcca gtctttttaa tgccagtttt gggaggactt ggtttccaag
     3541 gatcaacttt ctcagatgca gattttggtc tatcaggaat tattttagga atgttaaatc
     3601 aatttggttc acaagcaggc attgtgattg gtcttgttct tattctagca gttatgtttg
     3661 gagtatcctt tattaaaaag ccatctgcaa aggaggaata agggatgatt ttaagtaaaa
     3721 atagagaaga tgggttaaga aaatttgcga ctaacatccg attaaatact cttagaacat
     3781 tgaatcatct tggattcgga cattacggag gaagtctgtc tatcgtagaa gttttagcag
     3841 tgctttatgg tgaaataatg ccaatgactc cagaaatatt tgcagcacga gatagagatt
     3901 atttcatatt atcaaaaggt catggaggac cagctctata cagtacactc tatttgaatg
     3961 gtttctttga caaagaattc ctatattctt taaatacaaa tggaaccaaa ttaccgtctc
     4021 atcctgatag aaatctaacg ccaggcatag atatgacaac gggctcttta ggacaaggaa
     4081 ttagtgttgc aactggactt gcatatggtc agagaataag aaagagtccc ttttatactt
     4141 atgctattgt tggagatggt gagttaaatg agggacaatg ttgggaggct atacagtttg
     4201 cttctcatca acagttatcc aacttaattg tatttgttga tgataacaaa aaacaattag
     4261 atggttttac aaaggatatt tgtaatccag gtgatttcgt agaaaaattt tcagcatttg
     4321 gatttgaatc cattagggtc aagggttcag atattagaga aatttatgaa gggattgtcc
     4381 aattaaaaca gtcaaataat tcatcaccta agtgcattgt attagatact attaaaggtc
     4441 aaggggttca agagctggaa gaaatgaaat ccaaccatca tcttcgccct actgtagagg
     4501 agagacaaat gttaacttca gttgtagaaa gattaagtca ggaattggag gaaacagaat
     4561 gatgagaagc acgaaagaat tacggcatgt atatagagac ttccttttag aggctaatca
     4621 aagttattct gatatagtag tcttagaagc cgatttgtca agttcgatgg ctactaataa
     4681 tcttgaaaag gactttggag accgttatgt gaatgttggg attatggaag cagaaatggt
     4741 cggccttgca gcaggcttgt ctattcaggg gtttagacct tatcttcata catttggtcc
     4801 ttttgcttca cgaagagtat ttgatcaatt atttatttct cttggatacg cacaattgga
     4861 tgccactgtg attggatcag atgcaggagt aactgcagaa atgaatggtg ggacacatat
     4921 gccatttgaa gaaattggat tgttacgttt aattcctaaa tcgatcattt ttgaagcaac
     4981 tgatgatatc caatttcgtg aaatattgaa ccagacatta gacttaaaag gactaaaata
     5041 tattcgaaca attagaaaag ctccagttcc tgtgtatcaa ggtggagaag atttttctaa
     5101 aggctacatt gagttaaggc atggtgaaga tcttgtaatc gttgcttctg gtataatggt
     5161 tgctccaagt attcgagttg cagatgaact gtctaaatta ggttattcag taggtgtgat
     5221 agatttattt agaatcaaac cgataccaga acagataaaa acaatgttaa gtggaaaaac
     5281 tatatttact gtagaaaacc acaatcagat aggtggaatt ggcagtgctt tatgtgaatt
     5341 attctctgat gatggaataa caaaaattca tcggatgggt gttcaagaaa gatttggtca
     5401 agtagggaaa atggattatc ttcttaatga gtatggtttg agtgaatcga atataaaaga
     5461 gaaggttcta gaaatttata atgcaagata gatgttaaat acacttatct gaaagaattt
     5521 ctgtaaaaat tacattacgt tatttaaaga aagcggatta aaaagcatat tctggtcatc
     5581 agaaagtgca ctaatccgct ttgttgtttt taattttaaa tatttcacat gcgtatagaa
     5641 ttttctgaaa attcaagaat tttattctgt tcattgcctt taaattgtgc tataatagta
     5701 aaaactgaaa tgggagggat aagatgactg aattagataa acgtcaccgc agtagcatct
     5761 atgacagcat ggttaaatca cctaaccgtg ctatgcttcg tgcgactggt atgacagata
     5821 aggactttga aacatcgatt gtgggagtga tttcgacttg ggcggaaaat acaccatgta
     5881 acattcactt gcatgatttc gggaaactgg ctaaagaagg tgtcaaatct gcaggcgctt
     5941 ggcctgtaca gtttggaacc attaccgtag cggacgggat cgctatggga acgcctggta
     6001 tgcgtttctc tctaacatct cgtgacatca tcgcggactc catcgaggcg gctatgagtg
     6061 gtcacaacgt ggatgccttc gtcgctatcg gtggctgtga caagaacatg cctggatcta
     6121 tgattgctat tgctaatatg gatatcccag ctattttcgc ctatggtgga actattgcac
     6181 cgggaaatct tgatggtaaa gatatcgact tggtttctgt ctttgaaggt atcggaaaat
     6241 ggaaccacgg tgacatgaca gctgaggacg tgaaacgtct tgaatgtaat gcctgccctg
     6301 gccctggtgg ttgtggtggt atgtatactg ctaataccat ggcaactgct atcgaagttc
     6361 tagggatgag tttgccaggg tcatcctctc acccagctga atcagctgat aagaaagaag
     6421 atatcgaagc agcaggacgt gctgttgtta agatgttgga acttggtctc aaaccatcag
     6481 atatcttgac tcgtgaagcc tttgaagatg ctattactgt aacgatggct ctcggtggtt
     6541 ctacaaacgc cactcttcac ttgctcgcca ttgcccatgc cgcaaatgtt gacttgtcac
     6601 ttgaggactt caatacgatt caagaacgtg tgcctcactt ggccgacttg aaaccatctg
     6661 gtcagtatgt cttccaagac ctctacgaag tcggtggtgt ccctgcggtt atgaagtact
     6721 tgttggcaaa tggtttcctt cacggagatc gcatcacatg tactggtaag actgtagctg
     6781 aaaacttggc tgactttgca gacttgactc caggccaaaa agttatcatg ccacttgaaa
     6841 atccaaaacg tgcggatggt ccgcttatca tcttgaacgg gaaccttgct cctgacggtg
     6901 cagttgccaa ggtatcaggt gttaaagtgc gtcgtcacgt tgggccagct aaggtctttg
     6961 actcagaaga agatgcgatt caggccgttc tgacagatga aatcgttgat ggcgatgtag
     7021 tcgttgttcg ttttgttgga cctaaaggtg gtcctggtat gcctgagatg ctgtcacttt
     7081 catcaatgat tgttggtaaa ggtcagggag ataaggtggc cctcttgacg gacggacgtt
     7141 tctctggtgg tacttatggt ctggttgttg gacatatcgc tcctgaagct caggatggtg
     7201 gaccaattgc ctatctccgt accggcgata tcgttacggt tgaccaagat accaaagaaa
     7261 tttccatggc cgtatccgaa gaagaacttg aaaaacgcaa ggcagaaaca accttgccac
     7321 cactttacag ccgtggtgtc ctaggtaaat atgcccacat cgtatcatct gcttcacgcg
     7381 gagccgtgac agacttctgg aatatggaca agtcaggtaa aaaataaact catactcgaa
     7441 aatctcttca aatcacgtca acgtcgcctt gccgtaggta tggttactga cttcgtcagt
     7501 tctatccaca acctcaaaac agtgttttga gctgacttcg tcagttctat ccataacttc
     7561 aaaacagtgt tttgagctga cttcgtcagt tctatccata acttcaaaac agtgttttga
     7621 gcaacctgcg gctagttttc tagtttgccc tttgattttc attgagtatc aaaaagcaag
     7681 ccattttcgg cttgcttttt tcatctttaa aagtgattgg cctgcttaac gaggtggtag
     7741 tccaagggca atacggccat agcgactgat tcgtgtgatt ttccaggcag gcgaccaggt
     7801 aacttcaacc ttgatatctt tgataccctc gatttgtttc agacctgcca cgatttcaat
     7861 aggcaggctt tcggcgcaat cacaggcagt atcggtgaag gtcatgacaa tcttgcagag
     7921 ccccgtttca tccagattga tttcataaat cagacctaga ttgtaaacat ccaattccac
     7981 atctgtatca aaaactttct ctagtttttc gataatttgg tcttgcaagg ccaaagcacg
     8041 gtcattgatt ttgatatcgt ctctcatagc agtccctcca cgtgataaat atcctctatt
     8101 ttctcataat tctgacaatt tggcaagttt ttgatgaatt ttctgaaaaa tatgataaaa
     8161 tgaagaaaat acggaatcaa ggggaagtct atggagcaga ttggaaaagt ctttagacaa
     8221 ttacgagaat caagaaatat ctcactgaga caagcaaccg gaggacaatt ttcgccgtct
     8281 atgttgtccc gttttgaaac aggtcagagt gagctttcgg tggaaaagtt tctatttgct
     8341 ctggaaaata tatctgccag tgtggaggag atcctctttc tggcgagagg tttccagtat
     8401 gatacagatt ctgagttgag aaaagaaatt acagatgtct tggaaccaaa gaatatagca
     8461 cctcttgagg acttatatcg cagggagtat caaaagcatg cccattctca caacaaacag
     8521 aaacatattc taaatgccat tatgatcaag tcttatatga agagcatgga tgaaagggta
     8581 gagttaacag cagaggaagg aaaagtcctt catgattatt tgttttctac cgagatctgg
     8641 ggaatctatg aactcaattt attttcagtc agttctgcct ttttatctgt ttctcttttt
     8701 actagatatg tacgagaaat ggtacgtaaa tctgattttc taatggaaat gtctggtaat
     8761 cgaaactttt ttcatactat actattgaat ggctttttag ctagtattga gtgtgaagaa
     8821 tttaccaatg cctattattt taaacgtgtt atcgaagagc atttctacaa ggaaaatgag
     8881 acctatttcc gaattgttta tctgtgggca gaaggtctcc ttgatagcaa gcaaggtaga
     8941 gtcaaggaag gccagaaaaa gatggaggat gctgtccgta tttttgagat gcttggctgt
     9001 aataaatctg ccgaatacta tagaaatacg accgaatgtt gaatatctgc aaaccaagaa
     9061 aaaatttgaa gcgatagaac tattgccctc tctcaggtca ttacaaaagt tctatcgttt
     9121 ctttttgctc attttatttg ttgcatatat tcaagagttc tccctctcaa atttctaagt
     9181 gctatactat agtcatactt catatagagg ttcgaacaag aagggagatt atctatgaaa
     9241 ctattgttta gaaatccagc ttatagaatt ttgactttat catgcttctt caatgctttt
     9301 ggtgcttcga ttttcaacct ggtctttatc gtctatgcat cgaccttgtc acaagcatct
     9361 tttgctgttg ctatggcgaa tattgtcatg attcttccga ccctctttac agtttttgta
     9421 gggattcggg cagattacac gagggacaag gtcaaatgga tggtctatag cggtttgttt
     9481 caggcggttc tattttttct agcagcccta gttgttcagc aagctagtct ctttgccttt
     9541 tctagcctgt gtttgatcaa tgtcattagt gatatcatca gtgattttgc aggtggcctg
     9601 cgtatgcctc ttattaagga aaaagtagct gaagatgatc tgatggaggc ttattctttt
     9661 tcacagttca tcacctatat ttcagctatt ggtggtcaag ctttcggagt ctggctctta
     9721 gctctatcgg tcaacaattt ttctctcgtt gcgggaatca atgcctgctt tttcctagta
     9781 tcagccacta tcctcttttt aggaaaaagc aaattgagcc tgtcaatgtc atctgctgat
     9841 ggtgaaaact taaaaaatga gaagctttct atcaaagacc agttcctaac aatttaccga
     9901 aatttacgtc tcgtttttct taaaagtgga cagaaaaact ttggttttat gctctttgct
     9961 gtcttgctta ttaattcctt gggtggcgct ttgggtggaa tttataatat cttctttttg
    10021 agccattctc tcttgaattt ttcttataca gaggcactat ttatcaatca attctgtgtt
    10081 ttagtagcag tcatcatcag tagccttacg ggcaatgatt attttgggaa gcagtccttg
    10141 cctagattga tgatgtgggc gaccgtagga cttagtctag ttggtttggc taatttattc
    10201 aatcaagtcg tgcttggttt gctatttctc ttctttaccc tgtatgtgtc tggtaaagtt
    10261 caaccaaaga ttagtgccat gctcatgaaa aatctagctc cagaggttct agctcgtact
    10321 agtaattttt taggtctatt gtttacctta tccatacctg tgggaacagc ttgtttttca
    10381 ctagtagccg tatggaatat acagttgact tggatgctat ttgttggtct ttccttgcta
    10441 gctatttttt tgacaattct taatctcaaa aatgatatct aaatcctaat ttttttctta
    10501 ctgttttaat ccctttattt gtggtaaaat aagactatta agtttaaaga ggattcccta
    10561 tgaaattaca aaaaccaaaa ggaacgcagg atattttacc tgctgaatct gctaagtggc
    10621 agtacgttga gggctttgcc cgtgagattt tcaagcgcta taactatgca gaagtgcgca
    10681 cgcctatttt tgagcattac gaggttatca gtcgctctgt cggagataca acggatatcg
    10741 taaccaagga aatgtacgat ttttatgaca agggtgaccg tcatattacc ctccgtccag
    10801 aaggaactgc gcccgttgtc cgttcctatg tggaaaataa actcttcgcc ccagaagtgc
    10861 aaaagccaag caagttctac tacatgggac ctatgttccg ttatgagcgt ccacaggcag
    10921 ggcgcttgcg ccaattccac cagattggtg ttgagtgttt tggttctagc aatccagcta
    10981 ccgatgtgga aacaatcgtt atggcagccc attttttgaa ggaaatcggt attcaaggtg
    11041 tcaaattgca cctcaacact cttggaaatc ctgagagccg tgcagcctac cgccaagcct
    11101 tgattgacta tttgacaccg ctcaaggaga ccttgtctaa ggatagccaa cgtcgcttgg
    11161 aggaaaatcc tcttcgtgtc ttggactcta aggaaaaaga agacaaggtg gcagtagaga
    11221 atgcgccgtc tatcttggac tttcttgatg aagaaagcca aactcatttt gatgctgtga
    11281 gtcagatgtt ggaaaatctt ggagtagatt acatcatcga taccaatatg gtgcgtggtc
    11341 tggactacta caaccacacc attttcgagt ttatcacaga gattgagggc aatgacttga
    11401 cagtctgtgc gggtggtcgc tacgatggtt tggttgctta ctttggaggc cctgaaactg
    11461 ctggatttgg ttttgggctt ggtgtagagc gcctgcttct catccttgaa aaacaaggcg
    11521 tggccctccc tatcgaaaat gccctagatg tctatatcgc agtcttgggt gatggagcaa
    11581 atgtcaaagc cctagaacta gtccaagccc ttcgccaaca aggtttcaaa gcagagcgtg
    11641 attacctcaa ccgtaaactc aaagctcaat tcaagtcagc cgatgtcttt gcagctaaga
    11701 ccctcatcac cctaggagag agcgaagtcg aaagcagaca agtgacagtc aagaacaacc
    11761 aaacccgaga agaagtgcaa gtgtcacttg agacaatcag ccaaaacttc tcagaaatct
    11821 ttgaaaaact aggattttat actcaatgaa aatcaaagag caaactagga agctagccgc
    11881 aggttgctca aaacactgtt ttgaggttgt ggatagaact gacgaagtca gctcaaaaca
    11941 tggttttgag gttgtagatg aaactgacga agtcagtaac catacctacg gcaaggtgaa
    12001 gctgacgtgg tttgaagaga ttttagaaga gtattaatga tagataaagt ggtcaggaac
    12061 ttactcctga cctttttctt ttgcaaaatg acaaaaatca taaacttttt gacaaatata
    12121 tttatcaaaa agaaaaagat gtgttacaat gaattcaagt taagaaatag gaagcagaaa
    12181 ggagttataa tgtgggtact agtatttata ctatttatga ttttctttta ttctaataat
    12241 tctaaaaaaa tcaagaaact agagaataaa atcaaaaaac ttgagcgaaa agagaaagga
    12301 aacgcagaaa tgtcgagatt attacaagaa atgattggaa aggaaccaat tataacggga
    12361 gtgtatattg ggccagataa ctgggaagtt gtggatgttg atgaggaatg ggtcaaacta
    12421 cgtagtgttg ataaaaaggg gaaagaaaaa ttcaagttgc aacgtattga agatatccaa
    12481 accgttgaat ttgacggaga gtaggtgtgt aacatgcaac taaaaaatcg tctaaaagag
    12541 cttcgagctc gcgatggtct caatcaaacc gacctagcca aactggcagg ggtttccaga
    12601 cagaccatta gcctactaga acgggatgag tacaccccat ccattatcat tgccctgaaa
    12661 atatctcaaa ttttcaacga aacagtcgaa tcggtatttc gtttggagga ggacgagtga
    12721 tgaacaagta taaagtgatt tattatgtag tggtcatagc tttattagtc agtgtatttc
    12781 tactgattgg gatggaccta agctggttta atccctatca aagcgaccaa tttgtttggg
    12841 tctactttgc tctcatccca gtaattgaat ggattgaaaa gaaatccaaa aatctagcaa
    12901 gtgaaaaagg agaatgaata tgaaaaagaa acgtagattg ttatttttga tgtctattgt
    12961 cttggggggg ttcttgggca tgtttgtagg gatgtttaag gcacgtgtcg aatcccacga
    13021 aattatttta gatgtaaaag ccttgatgcc atggatatca gctatttgtt tactgatagg
    13081 tttcattagt atgtttttga ctttcaattt cttaaagaaa agcagaaaat ttcattcctt
    13141 gtatcaagag gaaatggatg acgatctgaa tgaaacctat tatgtgcaaa tgtatcggaa
    13201 tcttgagttt ggaaccattg cttttaatat tacaggtgta gcgattccat tggctatttt
    13261 tatttcatta agtgaggtga ttatattgca tacaaaccct caaacatttt tcctttcttt
    13321 cttactcttt gtggtattct tagtcgctca aaaatctctt tttaaaacca ttgcgattgt
    13381 tcgtcagttt gatttggaat ttttcgctac accaaaggat gtcttgaact atataaattc
    13441 ttatgatgaa ggggagcgtc aggctaattt ggaacagagt tttcgaattt tattccaatt
    13501 acaccaatat gtcttaccag ccttatatat ttttcttatt atcatttctt tcttgacagg
    13561 agagattcag ttactagctt tcttgcttgt aggagccatc catgtttata tcaatgtgat
    13621 gcagttacct atggtaaaac gttatttcaa ataaaggagt tatctatgaa actacttaaa
    13681 aaccttggct ggtttcttct agcccttcta tcctttttct ttatctatgg ctttattcag
    13741 gggctcgcga ctgcgtcgct tgctttaggc gcttcaccct atgctgttac tctactctat
    13801 gtggtcttgg ctggagtata tgtgtacggc atttacaaat ggtatcagaa agctcctgtt
    13861 tatattgaga agagcggctt taaccgattt atttggcttc ctgccttggt ttggttctta
    13921 tctctggtcg ttcaattctt cttgccagat gatccttcag taaatcaaca aatagcgaca
    13981 gacttgacct tgtctcaacc acttttctca ttctttgctg tggttatttt tgctcctttg
    14041 acggaagaga ttgtttttag agggatgtta gcacgctatc tctttcctaa gcaggacaat
    14101 agtaaacgaa ccctgatttt tcttctggta tctagtcttc tatttgcctt gattcatttt
    14161 ccaggtgatg tgcaacaatt ttttgtctat tttagccttg gttttagttt gggtttggct
    14221 tacattagca gaaaaggtct ggtctacagt atttctcttc acgctttgaa taatttagtc
    14281 ggctttttga tgattctcat gctataatag agtcaggagg tcacatgaaa cgagtaattt
    14341 tattagcagt gattcaggca gtcgttctat ttttcatcat tggagcgcta gcttatgcct
    14401 tcaaaggcga tttcttctat aactatctag cagttgtctt tgctcctatt gcaggtgtac
    14461 tgcgttttgg gacggcttac ataacggaaa ttgtcttgcc tcgaaaggca gccgaaatcg
    14521 ctgaaaagcg taaagcaggc aaaaattcaa aataaaagag tccggtgaag ttcatcggat
    14581 ttttgtatta tactcaatga aaatcaaaga gcaaactagg aagctagccg caggttgctc
    14641 aaaacactgt tttgaggttg tggatgaaac tgacgaagtc agctcaaaac atggttttga
    14701 ggttgtagat gaaactgacg aagtcagtaa ccatacctac ggtaaggcga cgctgacgtg
    14761 gtttgaagag attttcgaag agcattagcg ctaattttta gggctttcac ctgactttta
    14821 aagactggca aacttttctg atgattttca tgaagagcct gcgcttttat ggtaaaatag
    14881 taacagaata aaagaggaga gaaataatga aacgtagtat gtatgctggt cgtgttcgtg
    14941 aggaacacat cggacaagaa ataaccttga aaggatgggt tggccgtcgt cgtgaccttg
    15001 gtggtttgat ctttatcgat cttcgtgacc gtgaaggaat catgcagttg gttatcaacc
    15061 ctgaaaaagt atctgcagag gttatggcaa cagctgaaag ccttcgtagc gaatttgtta
    15121 ttgaggtgac tggtcaggtc gctgcgcgtg agcaagccaa tgataagttg ccaactggtg
    15181 cggttgagtt aaacgtgaca gctcttattg tgcttaacac agctaagaca acaccatttg
    15241 agattaagga tggcattgag gcaaatgacg atacacgttt gcgttaccgt taccttgacc
    15301 ttcgtcgtcc agaaatgttg gaaaatctta aacttcgtgc caaggtgacc cactctatcc
    15361 gcaactactt agatgagttg gagtttatcg acgtggagac accattcctt tctaagtcaa
    15421 cgcctgaagg ggcgcgtgat tatttagtgc cgtctcgtgt taataagggg catttttacg
    15481 ctcttcctca aagtccacaa atcacgaaac agctcttgat gaatgctggt tttgaccgtt
    15541 actaccaaat cgttaaatgt ttccgtgacg aggacttgcg tggagaccgc cagcctgaat
    15601 ttactcaggt cgacttggaa acgtccttcc ttactgagca agaaatccaa gatattacag
    15661 aaggcttgat cgcgcgcgtg atgaaggaaa caaaaggcat cgaagtaacg ctaccgttcc
    15721 ctcatatgaa atacgatgat gctatggctc tttacggttc tgacaagcca gatactcgtt
    15781 ttgacatgtt gcttcaggac ttgacagaag tggtcaaagg tgtagacttt aaagtctttt
    15841 cagaagcact tgctgtaaaa gcgattgtgg tcaaaggagc tgcggacaac tattcacgta
    15901 aagacatcga caagatgacg gaagtagcca aacagtatgg tgccaaaggt cttgcttggg
    15961 tcaaggtggt tgatggagaa ttaaacggac cagttgccaa gttcttgact ggtatccaag
    16021 aagaattgac aacagcgctt gctcttgaag ataaggactt ggttctcttt gtggcggata
    16081 cgcttgaagt ggctaatgca acactgggtg cccttcgtgg acgtattgct aaagagcttg
    16141 gcttgattga taatgataag ttcaacttcc tttgggtggt tgactggccg atgtttgaat
    16201 ggtctgaaga agaaggccgc tacatgagcg cccaccatcc attcacactt ccacaggaag
    16261 agactgctca cgaattagaa ggtgatttgg ctaaggttcg tgccattgct tacgatatcg
    16321 tcttgaacgg ttatgagctt ggtggtggta gccttcgtat caaccaaaaa gaccttcaag
    16381 aacgcatgtt caaggctctt ggtttctcag ctgaagaagc caatgaccag tttggtttcc
    16441 ttcttgaagc catggactat ggtttcccac cacacggtgg tttggctatc gggcttgacc
    16501 gttttgtcat gttgcttgct ggagaagaaa atatccgtga agtcattgcc tttcctaaga
    16561 acaacaaggc aactgatcca atgacacaag ctccatcaac agtcgctctc aaacaactag
    16621 aggaactcag cttacaagta gaagaagatg aaacaaacaa aacgaattaa gcggtggcgc
    16681 tattatctgc gccgctttgc ttatcagata aaaattttac gtgtcttaca aagtatctct
    16741 cgagaaaagt atgatgagaa gatttcggcc tctctggtct atggtttttt atcagcagta
    16801 gcagttaatt tctttttcca accagggcat gtgtattcga gtggtgcaac aggtctggca
    16861 cagattatct ctgccttgag taatcactgg tttggttttc atattccgat ttcgctaagc
    16921 ttctacgcca ttaacttccc tttgatggtc ttagcttggt atcagattgg ccataagttc
    16981 accgtcttta cctttatcac ggtatctatg agttccttct ttatccagtt tgtccctgtg
    17041 gcaaccttga cggaggatcc cattatcaat tccctttttg ggggtgttgt tatgggtttg
    17101 gggattggtt ttgctcttcg aaacaatatc tccagtggtg ggacggatat cgtcagcctg
    17161 actattcgca agaaaacggg taagaatgtc ggtagtattt ctttcttggt aaatggaact
    17221 atcatgctga tagcaggttt gacctttggt tggaaatacg ctctttattc tatgattacc
    17281 atctttgtct ctagccgtgt gacagacgca gtctttacta agcaaaagcg tatgcaggcc
    17341 atgattgtga caaatcatcc agagaaggta attgaaaaaa tccataaaaa attgcaccgc
    17401 ggagcaacca tgatccacga tgcagaagga acctataatc acgagagaaa ggcagtttta
    17461 atcactgtca ttacacgtgc agagtttaat gaatttaaac agattatgac acaagtggat
    17521 ccaagctcct ttgtctctgt ctcggaaaat gttcatattc taggaagatt tgttgagata
    17581 gataattagt gattaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc
    17641 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaaccatg ttttgagctg
    17701 acttcgtcag ttctatccac aacctcaaaa cagtgttttg agcaacctgc ggctagcttc
    17761 ctagtttgca ctttgatttt tattgagtat aaaaagatct tgggtaacaa ctcaatttca
    17821 gaagaaaagg aagtaaatct tcccacaata aaacgcatag tatcaagttt tttcaatacc
    17881 tgatagtatg cgtttttgct tttaacgact ttttgcccag tctcttattt ttcgataatt
    17941 ttgtgggcga tcaattgacg gtaacaaatt tgtttattgt ttttattatc attaataatc
    18001 tggagaatag tttcaaggga aacacgacca agctctaaac tattgatatc gacataggct
    18061 gccaagttga gcttgggatt aaccgagtca aagctgagaa cagggacatc cagctggtgt
    18121 ttggcaatat agttacaaac accttcagct aggaggctat cggttgtgat gatagcatca
    18181 atttgtggat cgtgcttgaa taatcgcttg ctaaatttat agcccttttc ttccagaaac
    18241 tcgtcggcaa agtagatgcg attgttgtca gtggtaagtt tgtaatgttt aagcgcctgt
    18301 tcatagcccg ttaaacggtc tttggtcacg aagagctttt tacttcctcc gataaaggca
    18361 atgcgtttgc agcctttttt gatgaaatat tcagtcgcat caaaaccagc ttgaacattg
    18421 tcgttgtcga caagtgggat gaaaggagat agagatttac ctaagataag gaaggggaac
    18481 tgttcttctg cgacgagttt tacgagaggg tcttcttctt gggcatagag aaagattagc
    18541 ccatctacac gcttgccgta gaccatttgt gaaatagcgt tgagacgctc cttctcatct
    18601 ttccctgttg ctatttgaat ggcatagtgg ttttcagatg cgacttgaga gatgccacgt
    18661 agaaccgatg gaaagaaagg attctggtag aaggcgtctg agtcatcagg aagaactaat
    18721 ccgataacct gagtatagct gcttaccaag ctacgagcgt taaggtttgg gtggtagttg
    18781 agttccttca tagctttgcg aacgcgtttt tttgtttcgt cgctaatggt tgatttattt
    18841 tgaataacac gggttacggt tgaaggcgaa acaccagcag ccttggccac gtctttaatc
    18901 gtaacgggca taaaaatctc ctatttatgg taatttggat cacggaaatg tgttttataa
    18961 aagatagtga ccagatacag aacaaaaaga atattttgta cagtaatcag ggttgtcata
    19021 ttttggccaa ataatcccaa aataagtgta atcagagtcg gcaatcctaa acagttcaag
    19081 ataaagtgat agcactcttt aaaggttcta aatgaaaaga ggcgtgattt cttagtgata
    19141 taaaggagaa gactagctcc tagagagacg ataaagaaat tcaaaccaaa gaggaagctc
    19201 gcaccgagaa ctaggaagag gctgatatag acacgatttt gttggtacca gtctttagaa
    19261 attgcttggg tcaagctgtc tttgcttttg aaactctcag tctgaatggc tcggtaagag
    19321 atgcgggtca gttccttgct ttccttgctg atgactagtt catttgtatc gaaatgcagt
    19381 tgcaagtcct taggtaattc cttgatttga cctggaccaa tcacaacaga aggggcttga
    19441 ctagctgttc cagtataagt taatgtgcca tcgacaattg tagcatgttc agagagatcc
    19501 tggacaacct catttgtcag aggttcatag acattatcga taaaagtttc tagcggatag
    19561 gtctcctggg agctgttttg gatagcaatg ggtaccatag acaagctgat aaggaagata
    19621 ctggtaaaga gaagttgaaa ccagttgagc tcgaaacgtt tggacagggg cttacgaaac
    19681 ccccaaatac ttgaaaaata ggaaaatgga tatggaagca taggtatctt tctaaaaggt
    19741 gttttctata tgagtattat tatatagaga aatgcgcttt atttcaagtc tagggggtaa
    19801 attgcttgct acaaggatat tatttacagt gacaatcgct aatagtcaat gaaaatcaaa
    19861 gtgcaaacca ggaagctagc tgcaggttgc tcaaagcaca actttgaggt tggagataaa
    19921 gctgacgtgg cttgaagaga ttttcgaaga gtataaaatg aaaaagggtg gcggggataa
    19981 attatccctt gtcgccacca cttgtaagtc ctgaaacaaa gttcttttgt aggaagaaga
    20041 agagaataca gattggaagg gcgatgagga tagcacctgc tgagaagtag gcaatcttca
    20101 agtttttcgc attgttaacg aaggtttgga gacctacggc aacagtaaag tattctttct
    20161 cacgaagcaa gaaactagag aggatgtagt ccccgaaagg tcccatgaag gcccagagag
    20221 cttgtacggc aaccattggg cgaacaagtg gtagaacaat ttgccagaag cggcggaagt
    20281 gtcctgcacc gtctagtttt gcagattcgt ctaaagacat tggcactgta tcgaagtagc
    20341 ctttcatgag ccaagcattc atcgggatac caccaccaac gtagaggaag atgaggaacc
    20401 agttgtggtt aagggcgttc aacataagcg ccataacgaa gaaggctgtc aaagcggcca
    20461 tagttggcac catttggatg atcaagaaga agaccaaact ttgtttacga gccaagaagt
    20521 tgtaacggct gtaagcataa ccagcaagta cgatgatact tgtttgaaca gccatggtaa
    20581 ttaaggcgat aatcaaagtg ttgaggtacc aagtaccgta caaggtttca gtgaagaggc
    20641 ctttaaagtt atcaaaattg aggtcgatat tagtatctag tttaaaggct gagacgttac
    20701 ctgctttaaa ggctgacatg atggtaatca acagtggata gataattaca attgatagac
    20761 caatcaggta aaggtaagta aggctttgag tcagtctacg tttgagttta attgagttat
    20821 tcatcttaga cgtcctccat atcaaatgcg tgtagtttct tgaatgcgat catagagatt
    20881 gagatgacaa tgatagagat aatcaaggta acagctgccg ccattgagta ttgaggagat
    20941 gtacctgttg tcaaacggta gatccatgag atcaagatat cggttgaacc agctccacct
    21001 ccgacactac caggtcctcc accattgaag aggtacatga tagagaagtt gttaaagttg
    21061 aaggtgtatt ggctaatcaa agtaggtgcc gcaacagcca aaatcattgg gaaagtgatg
    21121 ttgcggaatt tttgccaagc gttggcaccg tcaatataag ctgcttcgta aaggtcgtta
    21181 ggaatagatt gcaagatacc caaagtcaaa acgtagatgt atgggaatcc gagccaacct
    21241 tgcatcataa tcaaggcaat cttcgtccaa gttgggtctg ttttccaagg aataagagct
    21301 ccatcaagga aaggaaggaa tttagccaag attggcaata cttgagtgtt gatagcaccg
    21361 acactatcgt taaacatgtt tgagaatgtc aagatagtga tgaaggctgg gacagcccaa
    21421 ggaagaagga aaataacacc aaagatacgt tttcctttga taaatggttg gttggcaatg
    21481 atagctgtga agataccaat tacgatttgt aaagtagaag ctgccaaagc ccaaatgata
    21541 gtccaagaaa gaacagaacc aaaggcagaa cggaaggtac tcaagctcca aatgtttgta
    21601 aagttggtca aaccaaccca gtccaacaac ttgtttggtg gcaagtgttg gaagtcgtag
    21661 ttggtaaagg cgatcatcaa ggttacgata actgggaaga taatcgcgaa ggtcatggca
    21721 acataagatg gaatgatcaa gaggtaaggg aagccatttt cataaatccc tttgatcatg
    21781 tctttgagtg tgcgtggaac tggaattcca ttgttaatgc gttttgcaat cgtatgtgca
    21841 tctttgatat ttgagaaata aaagagtaca taaacgatta caaagattag atggaaggca
    21901 ccacgaatca gcataaagag ggaattatca cgacctggtt tgtcaccaag agtgatgagg
    21961 ttgctcaatt caggggttgc aagtgctagg aagtaaagga caaatacgat ggttacacta
    22021 aggaagataa aacctttggc tttttgttta ttgtaaatct gtcctaaccc aggaatgata
    22081 gacagcaggg ctgctttact aggttgttgc ttttccatat taactccttt cataggatac
    22141 tactttttta taagaaagct aaattatttg tgtctctatt gataaattca aagggggatt
    22201 tgatttccac cccccttgaa caaatttttt attcaccaaa tttttgtttg attgtttctt
    22261 tgatcaatgt tacagcatcg ttagcagctg ttttagcatc tttttgacca cttacagcat
    22321 caaagagcat atttttcgct ggatcccaaa ctgcagacat ttgagagatg tttggcagtg
    22381 gttgagtgtt cttgaactgt ttgataacag ctgttgtcaa ctcatcgttt ttaccttcag
    22441 cgtatgaacg agcctcagta ttagctggga tttcgttagt cttatcatat aatacttttt
    22501 gttgttcagt tgcaacaagg aagtctacaa atttttgaga agcttcaagg ttcttaacgg
    22561 cttgaggaat gacccaagct ttaccaccac cgaatgcagc atattctttt ccatttggaa
    22621 gagttgggat agttgcaact ccgtagttta ctttagcatc tttaaaggct tgagctttcc
    22681 aaggtccgtc gatgatagca gctgttttac cttcttggaa ttgagtttgg attaagtttc
    22741 cagcaccttc tgtatcttgc atacctttag gccatttttc gtaccaagat ttagcgtagt
    22801 tgatacctgc gatagaaccg tcgtttgcaa gaccgatgtc tttagcgtct ttaccgtttt
    22861 ggccaaagac gtaagcaccg ttaccggcaa gaagtccata tgtatagtag aagtttgtcc
    22921 agtcagctag gaaggcagta gttttaccat cttcaccagc gaatgcgtat ttgctatctt
    22981 tagcaaggtt ttccaagtca gcaaatgttt ttggagcatc tttcaccaag tctttgttgt
    23041 agtacataac aagtgactcg ataacggcag gagcaccgta aactttacca ttagcagctg
    23101 ttacaagaga tttagttgtg tcgtctgttt tagcaccatc gctcaatttc acttctgaaa
    23161 gttgtccgtc agaaccaagg ctacctacac ggtcgtatgg agccatcata acatcaggga
    23221 cattaccaga ttggttgtca agagaaagtt tatcaagacc tcctagagca tcaccagttt
    23281 taagagtgac ttttactcca gcttcttttt cataagcttt agcaacctct tcaatatagc
    23341 tcttatatcc ctcgtctaca tatacagtga gttctttgac ttcagatgaa ccagaatcag
    23401 caggcttatc agcagttttg cttccgcaag ctaccaaaag caagctagca agtgtaacag
    23461 ttccaagcac cgcagtgctc ttcataaatt tagatgacat agtgtattcc tcccaaagaa
    23521 tagcaagttt tattgataag gaaacgcaaa cgttttcctt tatgagctta gtatagcaca
    23581 aatagaaaac ggttgcaagt attttttgta aaaattttaa aaaattttta agcttgattt
    23641 gatagcataa ttttgcattt taatagaaga aaagtatgaa atagataaga atacagtatt
    23701 tttaataaaa atatatggaa tctgtctaaa gagggaaacc aggaggggct acctccctgg
    23761 ttctaatccc tatctatttt ctatggacgt ttgtgctttg ttacatataa attcaagctc
    23821 cctaaggagg ttttgtactt tgtagactgt ctcgtgagag tcaaacctta ggattagata
    23881 gttttaagtt atctttgcta aaatgagtta gtctccttaa aaataatcaa aaaagttttt
    23941 taaaaacgct tgcaattatg cttgaaaagg agtatactta taagtaacgc aaacgtttgc
    24001 gtctgcaaaa tacgcaacgt tccattattt taacacacga ggtgctatta tgaaaaaacg
    24061 tcaaagtggt gtgttgatgc acatctcttc tcttccagga gcttacggaa tcggatcatt
    24121 tggtcaaagt gcttacgact tcgttgattt cttggtccgt acaaaacaac gttactggca
    24181 aatccttcca ttaggagcaa ctagttacgg ggattctcct taccaatctt tctcagcctt
    24241 cgcaggaaac actcatttta tcgatttaga tatcttggtg gagcaaggtt tgttggaagc
    24301 aagtgacctt gaaggagttg actttggtag cgatgcgtct gaagttgact atgctaaaat
    24361 ctactatgca cgtcgtcctc ttttagaaaa agcggtgaaa cgtttctttg aagtcggaga
    24421 tgttaaagat tttgagaaat ttgctcaaga caaccaatca tggcttgagc tctttgctga
    24481 gtatatggct atcaaagagc attttgacaa tcttgcttgg actgaatggc cagatgcaga
    24541 tgctcgtgct cgtaaagctt cagcacttga aagctatcgt gagcaattgg cagacaagtt
    24601 ggtttaccac cgtgtgactc aatacttctt cttccaacaa tggttgaaat tgaaagctta
    24661 cgctaacgac aaccacatcg aaatcgttgg ggacatgcca atctacgtag cggaagattc
    24721 aagtgatatg tgggcaaatc cacatctctt caaaacagat gtcaatggta aggctacttg
    24781 tatcgcagga tgcccaccag atgagttttc tgtaactggt cagctttggg gtaatccaat
    24841 ctatgactgg gaagcaatgg acaaagacgg ctacaaatgg tggattgaac gcttgcgtga
    24901 aagcttcaaa atctacgata tcgttcgtat cgaccacttc cgtggcttcg aatcttactg
    24961 ggaaatccct gctggttccg atacagcagc acctggtgag tgggtgaaag gtccaggcta
    25021 caagcttttt gcagccgtta aggaagacct tggtgagcta aacatcatcg cagaagacct
    25081 tggcttcatg acagatgaag tgatcgaatt gcgtgaacgt actggcttcc caggaatgaa
    25141 gattcttcaa tttgccttca acccagaaga cgaaagcatt gatagcccac acttggcacc
    25201 tgctaactca gttatgtaca caggaacaca cgataacaat acggttcttg gttggtaccg
    25261 taatgagatt gatgatgcga ctcgtgagta catggctcgt tacacgaacc gtaaagaata
    25321 cgaaacagtg gtacacgcta tgcttcgtac agtattttca tcagttagct ttatggcaat
    25381 tgcaactatg caagatttac tagaattgga tgaggcagct cgtatgaact tcccatctac
    25441 ccttggtgga aactggtctt ggcgtatgac tgaagatcaa ttgacaccag ctgtcgagga
    25501 aggtttgctt gacttgacaa caatttatcg ccgaattaat gaaaatttgg tagatttaaa
    25561 gaaataagac aataatcagg agacaactaa acatgttatc actacaagaa tttgtacaaa
    25621 atcgttacaa taaaaccatt gcagaatgta gcaatgaaga gctttacctt gctcttctta
    25681 actacagcaa gcttgcaagc agccaaaaac cagtcaacac tggtaagaaa aaagtttact
    25741 acatctcagc tgagttcttg attggtaaac tcttgtcaaa caacttgatt aaccttggtc
    25801 tttacgacga tgttaaaaaa gaacttgcag ctgcaggtaa agacttgatc gaagttgaag
    25861 aagttgaatt ggaaccatct cttggtaatg gtggtttggg acgtttggct gcctgcttta
    25921 tcgactcaat tgctactctt ggtttgaatg gtgacggtgt tggtcttaac taccactttg
    25981 gtcttttcca acaagttctt aaaaacaacc aacaagaaac aattccaaat gcatggttga
    26041 cagagcaaaa ctggttggtt cgctcaagcc gtagctacca agtaccattt gcagacttta
    26101 ctttgacatc aactctttac gatattgatg ttactggtta tgaaacagcg actaaaaacc
    26161 gcttgcgttt gtttgacttg gattcagttg attcttctat tattaaagat ggtatcaact
    26221 ttgacaagac agatatcgct cgcaacttga ctctcttcct ttacccagat gatagtgacc
    26281 gtcaaggtga attgctccgt atcttccaac aatacttcat ggtttcaaac ggtgcgcaat
    26341 tgatcatcga cgaagcaatc gaaaaaggaa gcaacttgca tgaccttgct gactacgcag
    26401 ttgtccaaat caacgatact cacccatcaa tggtgattcc tgaattgatt cgtcttttga
    26461 ctgcacgtgg tatcgagctt gacgaagcaa tctcaattgt tcgtagcatg actgcctaca
    26521 ctaaccacac aatccttgct gaggcgcttg aaaaatggcc tcttgaattc ttgcaagaag
    26581 tggttcctca cttggtacca atcatcgaag aattggaccg tcgtgtgaag gcagagtaca
    26641 aagatccagc tgttcaaatc atcgatgaga gcggacgtgt tcacatggct cacatggata
    26701 tccactacgg atacagtgtt aacggggttg cagcacttca tactgaaatc ttgaaaaatt
    26761 ctgagttgaa agccttctac gacctttacc cagaaaagtt caacaacaaa acaaacggta
    26821 tcactttccg tcgttggctt atgcatgcta acccaagatt gtctcactac ttggatgaga
    26881 ttcttggaga tggttggcac catgaagcag atgagcttga aaaacttttg tcttatgaag
    26941 acaaagcagc tgtcaaagaa aaattggaaa gcatcaaggc tcacaacaaa cgtaaattgg
    27001 ctcgtcactt gaaagaacac caaggtgtgg aaatcaatcc aaattctatc tttgatatcc
    27061 aaatcaaacg tcttcacgag tacaaacgcc aacaaatgaa cgctttgtac gtgatccaca
    27121 aataccttga catcaaagct ggtaacatcc ctgctcgtcc aatcacaatc ttctttggtg
    27181 gtaaagcagc tccagcctac acaatcgctc aagacattat ccatttaatc ctttgcatgt
    27241 cagaagttat tgctaacgat ccagcagtag ctccacactt gcaagtagtt atggttgaaa
    27301 actacaacgt tactgcagca agtttcctta tcccagcatg tgatatctca gaacaaatct
    27361 cacttgcttc taaagaagct tcaggtactg gtaacatgaa attcatgttg aacggagctt
    27421 tgacacttgg tactatggac ggtgctaacg tggaaatcgc tgagttggtt ggagaagaaa
    27481 acatctacat cttcggtgaa gattcagaaa ctgttatcga cctttacgca aaagcagctt
    27541 acaaatcaag cgaattctac gctcgtgaag ctatcaaacc attggttgac ttcatcgtta
    27601 gtgatgcagt tcttgcagct ggaaacaaag agcgcttgga acgtctttac aatgaattga
    27661 tcaacaaaga ctggttcatg actcttcttg acttggaaga ctacatcaaa gtcaaagagc
    27721 aaatgcttgc tgactacgaa gaccgtgacg catggttgga taaagtcatc gttaacattt
    27781 ctaaagcagg attcttctca tctgaccgta caatcgctca gtataacgaa gacatctggc
    27841 acttgaacta atactcttcg aaaatctctt caaaccacgt cagctttatc tgcaacctca
    27901 aagcggtgct ttgagcaacc tgcggctagc ttcctagttt gctctttgat tttcattgag
    27961 tataagatac aaatttatac taatacatct tgtaaaaaag cgagtttcga ttgaaattcg
    28021 cttttttaat gatgtagatt tgggtcaatc ttgtctaaaa atagggaaat cctagataca
    28081 gtgaaggctt taaatgctgg tttttactgt cctcagcctt atattttttc gtagttgatt
    28141 acctcatacc tcttgtattc gcttacataa agtattataa tataattgta ggaaagaagg
    28201 tgtttttatg atatacacac ttaaattggt gttgtttatt acctttcttg taataagctt
    28261 gttacctgat aagatttttg gaaaaaataa aaaaatttgg aaaatagttt ttgcaatatt
    28321 gacggcagtg gcagcattgt catttatgta ctaagttatt ttaagaatgt agggaaataa
    28381 accctacatt ctttttagtt ttttctgttt tctaaattct atttatccaa gcgcttcaac
    28441 atttcttgct tcttcgcttc aagttctgca cgcttttctt cgatttcggc atgttttttc
    28501 tcgagttcag aacaacttgc accattgcta aattcttttc gccatcagga gatagggtga
    28561 gtcgacatgt ttattactca cccaaagcag tcctacaaag caggaatttt ctgttacttt
    28621 tttggaaata gtaacgttta tacagctttg acacttcgta tcaaagcgcc aaacacactc
    28681 cgagggattt acagaaagca gaaaaggaat gatctggtat aagatcattc cttttctctc
    28741 tttttcttta agtaattata tacaatgtac gacgaagtcg tcattgcaat gctgatccac
    28801 cacctaaagg gaactttaaa caacattgat aagataaaga atataaacaa cgaaaatacg
    28861 ttatacccaa ttaattttat tgtatatctc atgattaaaa gttaatcctt ccgttgttag
    28921 gaatggcatc atttttatcc cataattgtg ctaaataagt ccccgatgat aataaattca
    28981 tagcgaattc taaagcaaca tcatttacaa accaactaac tagatatcta gaaattgctg
    29041 aacgaatagc actttttgct gcatgttttc cttttacttt aattagattt gcaaggcctg
    29101 cagtagttcc tcctaatgct aaagctattg cagtatctaa tagagcaccc atttgattaa
    29161 ctgtaatacc ttgccaagct gctctaaatg gagagtatgt aggtgggatt gtataatcgc
    29221 cttgtaattg tcggttaatt acttctttga tccattgttg tgagacgtct ggatgaaaag
    29281 attggatttc gtttgcaagt gtatttattt gttcttctgt tagagaagtg acaggttgaa
    29341 gttccatatt tgtttcaatt tgtgatactt gttcagaagc gtatacagct gaaacacttg
    29401 gaatcgctga tacaattaac acaattgacg tcaaaaaaac cgaaataaat ttcattaatt
    29461 tgttcatgag cttttctcct ttttatttgt atctgcttac attttatcat atactgttat
    29521 tatagtcaaa aaaatatgct attatgttaa aaaaatattt ttcaaaatat aaatggacgg
    29581 atttattttg gattttattt gttattttga cctgcctcta tattggtaac catgatttgt
    29641 ttactctcaa tcatcaagaa ttctcttttc gtggtagcgt ttggggtctg gtactggcct
    29701 tatatcactt actattcatt gataagtttg ttatatcgaa tcgaaaataa agattagagc
    29761 tatgcttgac tgtgtacttt taggattgat tttggaggaa gattttgtct ctattattta
    29821 ttattttaaa tttatttatt ttgtataaga tctattcttt gaggcgggaa aaatcgaaat
    29881 acttgattta tacggcctat atcatatttg gggtaaatgt agtatatggt attcaatggt
    29941 tattaagaga actgatttca actatttccc cttaatgtgt atggaaacta taacaaaacg
    30001 cataagatta aggtttgtgt acctgttctt atacgttttt gtcatattga agattttcgg
    30061 taagttttct acttttgcga agtctagttt atactcaatg aaaatcaaag agtaaactag
    30121 ccgtaggttg ctcaaagtac agctttgagg ttgcagataa aactgacgaa gtcagctcaa
    30181 aacatggttt tgaggttgta gatgaaactg acgaagtcag taaccatacg tacggcaagg
    30241 cgacgttgac gtggtttgaa gagtattaga atgctttccc aaccaaaatc tctgcttcga
    30301 tggtaatctc tgtcagtttg ctccagtcaa ttttgctctg gtcaacgtga aagaggagag
    30361 gagtcatact gagtagggct tggagttgtt ctgctgtgat agtcttagtc agagaggcag
    30421 tttgactaga taggatggta aagtgttcct ggaaatgctc cttgatatct tggttagaat
    30481 actccttgtt tgtcagctgg tcctgtactc tttgacggat ttctttgagg tgattttcag
    30541 ttgggataac ctttatcaag ataccgtctt tggataaaac gcgacgaaat tctccatagt
    30601 tggcaggtga gaagatatca agcagaatat ccatgttatc gtcttttata ggaagtcgtg
    30661 ccaagtcgcc aacgaaccaa ttgactgccc agttgggttc acttttagca gcgatttgga
    30721 ctgaatcttt ggagatgtca aaggcataga aagttttttc agagtgactt tcttgtagtt
    30781 tgcgagaata gaatccttca ccacaaccga tatccaaaat tgttgtggta gtttttgagc
    30841 ttgcaagcaa gtcagataca gcatctaaga tagcttggta aaagccggct tctaggattt
    30901 gttgacggtt ttgaaaattt tccttgtcat agttagcaga ttgcttgatt tgaggtgcta
    30961 gattgacata gccaaatttc gccaagtcaa aagaatgacg gttgcagcac ttgaaattag
    31021 tctctaacag agtcagattt tcttgacaga taggacaggc aaaggcagtc gcagaagcaa
    31081 aacgctgaag tttgggcttg agatttgtat tcatagttta agtgtatcaa aagaggcaaa
    31141 tgaaagcaac tttaggaata agtagatggg agattcagta gaaataaaac taattctcca
    31201 atttatagaa tgaaattgct tttatatcta aattgctata taataatgat aaggaggaaa
    31261 taagtatgtt aaaagaagta ttaaccgttg caaaagttgc gaaaaaatct tcattatttt
    31321 tgggtggtgt cgcatttggt acccttggtt tgaaaatctt agcaagtaag gaagctaaaa
    31381 aaggttattc taaagctttg gctaaggctt acaagttgaa agacgagcta gatgcatctg
    31441 tttctgtcgt gaagcaacat ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc
    31501 aagagaaaaa agaagagcaa ttagatagcc ttataggtga ataatatgtc ttttaaagtg
    31561 ctacatagag gataccaaca tatccgacta tcatcttctt tttcacttac cttggatatt
    31621 caagactatc ttcgttcctt ggcgagagat gaaaagggga ttgagtctat ccagttttac
    31681 atggatcaac agcactttac tctacgcata aaagaaggct tttctgtatt agataatgca
    31741 gaagcctttt taaaaagaat tgataaaggg aaagtttctg agttgatgac tcttcccatt
    31801 cgtagagaag agagtgctta ttctattgtt tcaggtgcag cggttaagcg tgtacttttt
    31861 cgtagttttg tgccgtatcc tattcgctat atatggactt gttatcaggc tttgggttat
    31921 attagagaag cctatcaaac actagcgcgt aaggaactaa cgatggaagt cttggactgt
    31981 tcggctattt tattgtcttt gtttatgaac caatccaaga cagctagcaa tatcatgttt
    32041 atgcttgatt tggggaatca tttagatcag tggtccttga aaaaaactgc aacagattta
    32101 gaacagagtc ttcttgcaaa agagagcgat gtattcctag tacagggcga tacagttgtt
    32161 agtatcaaga gttccgatgt tcaaatagga gatgtcttga tcttatctca aggaaatgaa
    32221 attctgtttg atggacaagt agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca
    32281 ggagagagtt atccagttga aaaaagagag tctgatttgg tttgtgcaaa tacagtatta
    32341 gaaactggag agttacgcat ttgtgtaaca gataatcaga tgaacagccg tattttacag
    32401 ctgattgagt tgatgaagaa atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc
    32461 aagatggcgg ataaagtcgt caaatataat ttcttggggg ctgggctgac ttacctattg
    32521 acaggttctt tttctaaggc tatttctttc ctattggtcg atttctcctg cgctttgaaa
    32581 atctctactc cggtagctta tttgacagtt atcaaggaag ggttgaaccg tgaaatggtg
    32641 attaaggatg gagatgttct ggagaaatat ctggaagttg atactttctt gtttgataag
    32701 acaggaacaa tcacaactag ttatcctata gttgaaaagg tgttaccttt tggagactat
    32761 agtgaggaag atattctcag aatcagtgcc tgtcttgagg aacacattta tcatcctatt
    32821 gctaatgcca tcgtcaagca agctgagata gagggaattg aacatgagga aatgcatggg
    32881 aaactccaat atatcgcaag caaggggatc aaatctcata tagatggcca accagttctt
    32941 attgggaatt atgtcttgat gcaggatgag cagattcata tcagttcaga acaaaatgct
    33001 ttaattgaag agtacaagag tcactacaat ctcttattct tggcttatca aaatgaattg
    33061 attggaatgt tctgcattca tactcctttg agaaaagaag caaaaacagc cttggataaa
    33121 cttaaggcac aggggaaaaa attgattctg gcaacaggag acaccttgat taggacagag
    33181 gaattagtca aagatttgcc ctttgatcag gtctatacag acttgaaacc tgatgggaaa
    33241 tttgagttag tagagaaact gcagaaagca ggtcacacta ttttgatggt tggagatgga
    33301 ttgaatgact cagcggcttt aactctatca gatatcggtg tggtgatgaa tgagagtgca
    33361 gatatttcta agcagatgag tgatatctta ttgttagata atcgtttgga tttcttccaa
    33421 gagttggatt cgttatcatc atctttgcaa acactcatca agaaaaatat tcaggatacc
    33481 gttgtcgtaa atagtagttt gattggcttt ggcttattta attggttcag tccttcaaat
    33541 ctctctatct tacataatct aacaaccttg cgcattgtcc tgcgtagcct gtctattaaa
    33601 aatagataga tgagagttat taacagcaaa aaggagttac ctttctcgag gttaactcct
    33661 ttgtttatag ataaatgttg aatagtttag taagtcaata caaagtattt tttcttccca
    33721 cgacggataa cagtcagttc attttctaac ttatcagcgt cactcaagac atagtcaagg
    33781 tcttggatgc ggtcgccgtt tacgtagatg gctccgtttt ggacgtcttc acgggcttgg
    33841 cgttttgagt taactatacc agatgagacg agcagttcca cgatattgtt gttttcgtct
    33901 gcctgtactt ggtagtttgg cacaccacga agtccttgtt tgagctcttt gacagaaagg
    33961 tttttgatgt ttcctgcaaa gagttgctca gtgatgttaa gtgcttcttt gtaggcttct
    34021 tctccgtgaa caagtgtaac aacttcacga gccaagactt tttgagccaa gcgttcgtgt
    34081 ggcgctgctt caaattgttt acgaatatct tcaatctcat caagtgacaa gaaagtaaag
    34141 attttcaaga agcgaacagc gtcagcgtcc atcacgttca tccagaattg gtacatttcg
    34201 tatggagaag tcttttcggg attgagccag acggcatttc cttctgattt accaaatttt
    34261 ttaccagttg catctgtgat tagtggaaca gtgataacgt gaccagtctt gtccgcctta
    34321 cgacgaagca attcggtacc agctgtcata tttccccact ggtcagaacc accgatttga
    34381 agagtgacat tatggtcttg gttaaggacg aagaagtcgt acccttgcat gatttggtaa
    34441 gcgaactcag tgtaagaaat tcctgtttcg atccgttttt taacagattc cttactcatc
    34501 atgtagttga ccgtgaagta ttttccaata tcacggagga agtcaatgaa gctgatgctg
    34561 ccaaaccagt cgtagttgtt gaccatgaca gccttgtttt cgccattttc aaagtcaaga
    34621 aaacgagaaa gttgtccttg gatagacttg acccagccat ctactgtgtc ttttgtttgg
    34681 agactacgtt cagcatcttt gaaggacgga tctccgatga gacctgtagc accgccaacg
    34741 agcgcataag gtttgtgacc tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg
    34801 tggcctaggt gaaggctgtc agcagttgga tcgtagccag tataataaga aacttgacct
    34861 tcttctaggg ctttacgcaa agcttcttca tcagtcgttt gaaatatcaa accacgctct
    34921 tttagctcat caaaaatgtg catgtgtctt ttctcctttt taaaattatt gtttctacct
    34981 attgtatcac aaacttgggc aatagcctag cagaataggg aagaaagtgg ctattttatt
    35041 gaaaatttcc cttttgtggt ataatagata aagtgaggaa atccatgcaa aatcaattaa
    35101 atgaattaaa acgaaaaatg ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag
    35161 ctagacctgg caagaaaggt tcaagtacca aaaaatctaa aaccttagat aagtcagcca
    35221 ttttcccagc tattttactg agtataaaag ccttatttaa cttactcttt gtactcggtt
    35281 ttctaggagg aatgttggga gttgggattg ctttggggta cggagtggcc ttatttgaca
    35341 aggttcgggt gcctcagaca gaagaattgg tgaatcaggt caaggacatc tcttctattt
    35401 cagagattac ctattcggac gggacggtga ttgcttccat agagagtgat ttgttgcgca
    35461 cttctatctc atctgagcaa atttcggaaa atctgaagaa ggctatcatt gcgacagaag
    35521 atgaacactt taaagaacat aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg
    35581 ggaaatttgt aggtttgggt tcctctagtg ggggttcaac cttgacccag caactaatta
    35641 aacagcaggt ggttggggat gcgccgacct tggctcgtaa ggcggcagag attgtggatg
    35701 ctcttgcctt ggaacgcgcc atgaataaag atgagatttt aacgacctat ctcaatgtgg
    35761 ctccctttgg ccgaaataat aagggacaga atattgcagg ggctcggcaa gcagctgagg
    35821 gaattttcgg tgtagatgcc agtcagttga ctgttcctca agcagcattt ttagcaggac
    35881 ttccacagag tcccattact tactctcctt atgaaaatac tggggagttg aagagtgatg
    35941 aagacctaga aattggctta agacgggcta aggcagttct ttacagtatg tatcgtacag
    36001 gtgcattaag caaagacgag tattctcagt acaaggatta tgaccttaaa caggactttt
    36061 taccatcggg cacggttaca ggaatttcac gagactattt atactttaca actttggcag
    36121 aagctcaaga acgtatgtat gactatctag ctcagagaga caatgtctcc gctaaggagt
    36181 tgaaaaatga ggcaactcag aagttttatc gagatttggc agccaaggaa attgaaaatg
    36241 gtggttataa gattactact accatagatc agaaaattca ttctgccatg caaagtgcgg
    36301 ttgctgatta tggctatctt ttagacgatg gaacaggtcg tgtagaagta gggaatgtct
    36361 tgatggacaa ccaaacaggt gctattctag gctttgtagg tggtcgtaat tatcaagaaa
    36421 atcaaaataa tcatgctttt gataccaaac gttcgccagc ttctactacc aagcccttgc
    36481 tggcctacgg tattgctatt gaccagggct tgatgggaag tgaaacgatt ctatctaact
    36541 atccaacaaa ctttgctaat ggcaatccga ttatgtatgc taatagcaag ggaacaggaa
    36601 tgatgacctt gggagaagct ctgaactatt catggaatat ccctgcttac tggacctatc
    36661 gtatgctccg tgaaaatggt gttgatgtca agggttatat ggaaaagatg ggttacgaga
    36721 ttcctgagta cggtattgag agcttgccaa tgggtggtgg tattgaagtc acagttgccc
    36781 agcataccaa tggctatcag accttagcta ataatggagt ttatcatcag aagcatgtga
    36841 tttcaaagat tgaagcagca gatggtagag tggtgtatga gtatcaggat aaaccggttc
    36901 aagtctattc aaaagctact gcgacgatta tgcagggatt gctacgagaa gttctatctt
    36961 ctcgtgtgac aacaaccttc aagtctaacc tgacttcttt aaatcctact ctggctaatg
    37021 cagattggat tgggaagact ggtacaacca accaagacga aaatatgtgg ctcatgcttt
    37081 cgacacctag attaacccta ggtggttgga ttgggcatga tgataatcat tcattgtcac
    37141 gtagagcagg ttattctaat aactctaatt acatggctca tctggtaaat gcgattcagc
    37201 aagcttcccc aagcatttgg gggaacgagc gctttgcttt agatcctagt gtagtgaaat
    37261 cggaagtctt gaaatcaaca ggtcaaaaac cagggaaggt ttctgttgaa ggaaaagaag
    37321 tagaggtcac aggttcgact gttaccagct attgggctaa taaggcagga gcgccagcga
    37381 caagttatcg ctttgctatt ggtggaagtg atgcggatta tcagaatgct tggtctagta
    37441 ttgtggggag tctaccaact ccatccagct ccagcagttc aagtagtagt tctagcgata
    37501 gcagtaactc aagtactaca cgaccttctt cttcaagggc gagacgataa ttctctaaat
    37561 gaagtggcca atcaatggat tgccactttt ttcttttcgt gttacaataa gggtatgaat
    37621 cagtatcaga aaaagattgt taacggaaaa atttattcgc tcctatccgg cttaatatgg
    37681 ggaatctgtg gaattttagg agagtacttc tttactcatt atcaggtgtc ttcgggctgg
    37741 attacctcta tgcgtttgac actggcaggg agtcttgtac tcatttggtc tgcaatacaa
    37801 ttaaaatcgc aagtgctaga tatttggcga gacaagaaaa attacctgcc ctttttagcc
    37861 tatgctattt tggggatttt ttcagttcag tattttttct atctctgtgt agaatactca
    37921 aatgctacga cagcaactat tttacagttt attagccctg tctttatcct cttttacaat
    37981 cgcttggttt atcaaaaacg agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg
    38041 ctgggtgttt gcttgatggc gacaaaggga gatctctctc agttatccat gacgccgcta
    38101 gctcttataa caggtttgct gagtgccatg ggtgttatgt ttaatgttat cttgccccaa
    38161 ccttttgcta agcgttatgg ttttgttcct acggttgggt gggggatgat tttggcaggt
    38221 ttgtttagca atgtcctctc gccggtttat cagctttcct ttactcttga tatttggagt
    38281 atcttgattt gcctcattat cgctttcttt ggaacggctt ttgctttttt catttccatg
    38341 aaggctgtgt ccttggtttc tcctttggtg gttgccgtta tcagtgccag tgaacctctc
    38401 tcttctgctc tcttgagtgt tttgttctta ggattagtag tggattggtc cctccttcta
    38461 gctatagcct tgattatttt acccatgata tttttgtcta tagaagaagc gaaagaaagt
    38521 agataaaaag tcttttctta attctaaaag tgtgctatac tagaatagtc aataaaacac
    38581 ggggagatag ttgtgaagag tgtttttagg ttgtatcggt aggggcttgc ttttaccgac
    38641 agcacgtttt atctcacatc cctaaaaaat catacctaaa aacagacaaa aaggtttcaa
    38701 atttgaggcc ttttttggta gaataggtat cattataacg aaccaggagg cacctatgac
    38761 tgctacaaaa atgaacgctc aagaaattat ccaatttatc gccaatgctg aaaagaaaac
    38821 cagtgtcaaa gtaacctttg aggggcaact cgcaactgct gtgcctagct ctgttgtcaa
    38881 actaggaaat gtcctattcg gagactggaa ggacgtggct ccgcttcttg aaggtttggt
    38941 agaaaatcaa gattatgttg tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga
    39001 taagcgtgct atcaacgctc gtatcgagcc aggtgctatt atccgtgacc aggtggaaat
    39061 tggtgacaat gctgttatca tgatgggagc tgttatcaat atcggtgctg aaatcggtgc
    39121 tggaaccatg attgacatgg gtgccatcct tggtggccgt gccatcgttg gaaaaaatag
    39181 ccacgttggt gcaggtgcag ttttggcagg tgtgattgag ccagctagtg ctgaaccagt
    39241 ctgtgtcgga gacaatgttc tcatcggggc taatgcagtg gttatcgaag gagtccaaat
    39301 cggtagtggt tcagttgtcg cagcaggagc tattgttacc caagatgtcc cagaaaacgt
    39361 ggtagtagca ggtgttccag ctcgtattat caaagaaatt gatgcccaaa ctcaacaaaa
    39421 aacagcgcta gaggatgcgc ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac
    39481 cctttttcca gcctctttct gctatatcgg aggacagata gatgttagat ttgattcaga
    39541 ctagacgaga tttacaccag attccagaga ttggcttgga ggagttcaag actcaggctt
    39601 atttgctgga tgtgattgag aaattgacta cgggcaagga ttttgttcaa attcgtactt
    39661 ggcggacagg gattttggtc tacctgcagg gaagtcagcc ggagcgaacc attggttggc
    39721 ggacagatat tgatggcctg cctatcgtcg aacaaacagg tctacctttt gcttctcaac
    39781 accaaggtcg catgcatgcc tgtggccatg attttcatat gaccattgcc ttaggctgtc
    39841 ttgagcgcgc ccttgaagag caacctaaaa ataatctgct cttcctattt cagcctgctg
    39901 aagaaaatga agctggtggt atgctcatgt atgaggacgg tgcttttgga gattggttgc
    39961 cagatcaatt ctatggtctc catgttcgtc cagatttgaa agtcggccag attgcgacta
    40021 atactcatac actctttgca ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg
    40081 gccacgcagc ttttcctcat gaagccaatg acgccttggt ggcggctagt tactttgtga
    40141 cccaagtgca gtcagttgtt agccgcaatg tcaacccaat cgagggagca gtggtgacct
    40201 tcggcgtttt tcaagctgga accaccaaca atgtcatcac agacacagct tttttacatg
    40261 gaactattcg tgccttgaca caggacatga gtctcttggt gcaaaagagg gtaaaaacag
    40321 ttgcagaagc ggttgcagct gcctttgata tggaagtcga agtggaactc aaacaaggtg
    40381 gatacctacc tgttgagaac aatccagcct tggcgcgtga actgatggac ttctttgacg
    40441 aaaaagacgg aatcgagttg attgatatcg aacctgctat gacaggcgag gactttggtt
    40501 atctcctttc aaaggttgat ggtgtgatgt tttggctagg tatcgatagt ccctacgctc
    40561 ttcatcaccc tcaaatgagt cctaaggaag aagtcttagc tattggggtg gctgcggtgt
    40621 ctagtttcct gaaaaagaag gcagcagaat agagggcttg tctatgaaat cggaattacg
    40681 caagcaagtc ttgcatgaaa tgaaggcttt atctcaagaa caaaaacagg ctatagacca
    40741 agctttaacc gagcgaattt tacaacaccc cttttatcaa gaagccaagg tcatcgcaac
    40801 ctacctctct ttttctcatg agtttcaaac gcgggaactg attgagcagg cgctgaagga
    40861 cggcaagagg gttttgacac ctaagaccta tcccaagggg cgcatggact ttgtggtcta
    40921 tgatccgcaa cagttggtaa aaacttcctt tggattactg gagccacagg gagatttgga
    40981 agttgtggat gtttcaaaga ttgatttgat tcatgttcct ggtctggctt ttacgacgaa
    41041 aggatatcgg ataggatacg gtggaggcta ttatgaccgc tatctggaac atttttctgg
    41101 tcgtgctttg agtacgatat atccttgtca aattcaggac tttatacctg aaaaccatga
    41161 tattcctgtt caggaggtat taattgatga aggaaatctt tgatagacgt taccctgtga
    41221 cgagtttctt cctcttagtg acggccttgg tatttttact aatgttggtc actgcaggcg
    41281 gaaactttga cagggcagat acattatttc gatttggagc catgtatggt ccagctattc
    41341 gcctctttcc cgagcaggtt tggcgtctct tgtctgccat ttttgttcat attgggtggg
    41401 aacatttcat tgttaatatg ctttcacttt attatcttgg aaggcaggta gaggagattt
    41461 tcggttctaa gcagtttttc tttctctatc ttttatcagg aatgatgggc aatctctttg
    41521 tttttgtatt tagtcctaaa tccttagcag caggcgcctc tacctctctt tatgggctat
    41581 ttgccgcgat tattgttctt cgctatgcaa ctcgcaatcc ttatatccaa cagctagggc
    41641 aatcttatct gacacttttt gtggttaaca ttattggaag tgttctgatt ccgggaatca
    41701 gcctagcagg ccatatcggt ggagcagttg gtggcgcatt tctagcagtt atctttccag
    41761 ttagaggaga aaaacggatg tataacacca gccagagatt aggagcggta gtcttgttcg
    41821 taggactcgc cattttgctt ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa
    41881 tttgtgtaat gaaaaaagat aaggcatttt ttgaacctta tctttttatt ttattccttc
    41941 tcagtcaatt cttttccaag ttggatgagg taattcttca aatcatcttt gacttgtgga
    42001 tgtttgaggg cgtagtcaat agatgttttc ataaagccaa acttatcccc aacgtcgtaa
    42061 cgagctcctg taaattcacg ggcaaaaaca cgctgtgttt tattaagagt atcgattgca
    42121 tcagtaagtt ggatttcatt tccagcacca ggagcttgct tttcgagaat ctcaaaaatt
    42181 tctggtgtga gtagatagcg accgatgatt gccaaatcac ttggagtctc ctcgggagct
    42241 ggtttttcaa cgaaagtttc aacgctatag agtccattgc ttccttcgcc ttgaggagca
    42301 atgactccat atgatgaaac gtcttcgtgt ggtacgggca tgacagcaat ggttgatgcg
    42361 tgtgtctttt cgtaatcatt catcagttgt tttgtcaaag gaacggcctt ctcgtctgtg
    42421 atatccatca agtcatcacc aagcataacg acaaaaggtt catttccgac gaaagccttg
    42481 gcttgcaaaa cagcatctcc gagaccgcgt ggatgagttt ggcggatgaa atgaaggcgc
    42541 atgccagttg tttcatctac caattttaac aaatccgttt tgcctttttc cttaagattg
    42601 tattcaagct caaagtttga atcaaagtgg tcctcaatag aacgttttga tttaccagtg
    42661 acaactagaa tatcttcaat acctgatttg agagcttctt ccacgataaa ctggatagtt
    42721 ggtttgtcta cgattggcaa catttctttg gcaagggcct tggttgctgg taaaaatcga
    42781 gttcctagtc cagcagcagg gatgactgcc tttctaactt ttgatgtcat aaaaatcctt
    42841 tctatagagg gttaagacca ctcattttct gctttaaatt cattgttcat gatgtcataa
    42901 atggcatctt tgatattggt tccgtgataa ataacttggt aaatagcctg tgtaatgggc
    42961 atatagactc caagttcttg ggctagttca taggctgatc gagtcgttga aattccttcg
    43021 attaccatgc ccatattagc ttctatatca gctagggatt ctcctcgtcc gagagcatct
    43081 ccagctctcc agttacgaga gtggatggaa gttcccgtta cgatcaaatc tcccacacca
    43141 gataagccgc tataggtcaa tggactggcc ccgagtgcta cccctaggcg ggtgatttct
    43201 gctaaacctc gagcgatgat ggctgcctta gcattatcac caaatccaag accatgtaaa
    43261 gctccagcac cgacagcaat aatattttta agagcaccag cagtttcaac cccgataaca
    43321 tccgtattgg tataaagtcg gaagtagtga ttactaaata gctcctgaac gtattgagct
    43381 gtttgtaaat ctttagaagc agcagttatt aaagttaggt cacgcacaat ggtctcttct
    43441 gcatgactag gccctgaaac aacgacgata tcactacgga gatgttcagg aatttcttct
    43501 tcaagaatgg ttgataatcg tttatggcta tcaggttcta atccctttga tgcgtgcatg
    43561 atgataacct tatggtccaa ggtttgtgca acttgctggg caacaagtcg tgtcactttt
    43621 gttgggacaa caaacaaaat cgcatccaca tttttcaatg tttctgctaa gtcggtgtag
    43681 gcaatgatat tttcgtctag aacgacatct ttaaagtagt gcttattagt atggtgtgta
    43741 ttaatttcat tgatttgctc gggaagattt ccccaaatac gtacctcgtg tccattgtca
    43801 tttaagactt gtgaaagggc ggttccccaa gaaccaggcc ccaagacggc gacggtttgt
    43861 ttttccatga tttcctcctt gatagatttc tttctcttat tatatcatat tctaggggat
    43921 tttgcacttg cattactggg gtatggtgga aaaatacaca aaaaccgaga tgaagggata
    43981 aactcttagt ctttagttaa agtgagaaga aatctgatag atagtttgat tcagtatatg
    44041 ctataaatag aggtaaacaa ctcaagaggt tcttgtaggt tgcgagagtt tggcgaaaaa
    44101 attaaaagat tacgtttggc taaaaaaatc agtcgttcag aattttgtgg tgatgagtct
    44161 gaattaagta tccgtcaatt aattagaatt gaaaatggag aatccagacc aacactaaca
    44221 aagttaaaat atatcgctga acgtttgggg gttgaagatt acaagttgat gccaagttat
    44281 atagagttgg ataaggaata cctagaattg aagtatttct tgatgaggac tcctacatac
    44341 gaagatgaaa ctatcgccca aaagaaagag agtgtttttg ctaagatttt tgaagagtat
    44401 tatgataggc tacctgagga agaaagattt atcatcccaa attattcata tctggcacta
    44461 acgaactaca cagttcaaaa attaccagaa aagctagttg aaatactgtc cttctggtga
    44521 ttttgcttaa tttctgatgt tcgagacatg attgaggaga tttgtcttga tttgttccta
    44581 aaaagggcag actcctccct tggtttgatg atcgattttt aaaataaggt gacttattct
    44641 gttaggcatg ttttcccctg ccctctagct ctatatggaa cagggagtat cagatttatc
    44701 tggcagattg tatcaaataa ggcttgaaac tgttttgaat aggcgtatag acttgagaat
    44761 ttgagaatat gtcgtctagc agtagagaca tattttccgg caatatgaag gaagagacgt
    44821 cgaaaacgct tgatagtcaa ggcctttact tcatcaccag ctagctgttt taaaaagagg
    44881 tagagattat aagccagaca gcccatcatc atacgtattt cattcttaat catggtcgaa
    44941 ctatctgtct tatccccaaa gaatcctgct ttcctttctt tgataaagtt ttcagcattc
    45001 cctcgttcac gatagaattg aaacagctcc tcactatcta cactgcttaa attggtcaaa
    45061 tgaacttttt tacaaccata aaaaagagca cttaatcgta ctcttctctt ttaaggatta
    45121 gttgaattaa ttcaaatcca ctagttctcc tgtttctagg tagactaggc gttcacaaat
    45181 gttagcaatg taatcagcga agcgttccag atgccctatg atataaaggt attgtgttcc
    45241 attgggaatt gaggtttctt ggtctttcat aagtccaatg atttcctttg ataaggcata
    45301 ataatattgg tcaatctgtt catctttttg agcaatacta atagcttttg aggcttggtg
    45361 caaaggaaag gcaaccaata aatcggctag catgctgagg gataatttac ccatttggtg
    45421 taactgttct tcgccagggg ctagttgatt ttcttttagt tgcaaaacag ctttggcaat
    45481 gcctgccata tggtctccca tacgttcaag gtctgaacaa gaagacatga tgctaatcac
    45541 aaatcgaagg tcagacactt gtggctgctg caaggctaac aaacgggcac aggtcaattc
    45601 gatagcgctt tgaccttggt tgatagcatg atccttattg ataattagct ttgccatctc
    45661 cttgtctttg gaggctaagg ccagtaaggc ttttgaagct gtttcaagga caagttgccc
    45721 tagtcctaaa aaggattgtt ctaattcatg caattctaag tcaaattgat ttctcatagg
    45781 tttttccttc cttatccgaa ccgtcctgaa atatagtctt ctgtgcgctg atcttttgga
    45841 ttggtaaaca cgtcaacggt atctccaaat tcgcaaattt ctcctgttaa gaaaaaagca
    45901 gttttatctg aaatacgtga agcttgttgc atgttatggg taacaatgat aatcgtataa
    45961 tcctttttta gttgctgaat gaggtcttca atttttaaag tggagatagg gtctaaggct
    46021 gaagtcggct catccattaa cagaatatca ggttctactg ctaaagctcg cgcaatgcaa
    46081 aggcgttgct gctgaccgcc agataaggac atggcactct ttttaagatc atctttgact
    46141 tcttcccaaa tggctgcccc ttttaaagat ttctccacta aggcatctaa ttgttttttg
    46201 tctcgaatac catgtgtcct tggaccataa gccacgttat catagataga catggcaaag
    46261 ggattaggct gttgaaaaac catccctaca cgcttgcgta gctgattaag gttgaatttg
    46321 ctactataaa tatcttgctc atctaagagg acttggcctt caatatggca agaaggaacc
    46381 aaatcgttca tccgattaag ggtttttaga aaagttgatt tgccacaacc agatgggcct
    46441 atcaaggcag taatctgtct ttctggtaat tgaatcgaaa tattttttaa ggcttgaaaa
    46501 tccccgtaaa ataagtctag gtgtctgact gaaaatgttc ccatactagg aagctccttt
    46561 cacaagtttc cgagataata agcttgatag agtatttatc attaaaacag taataatcaa
    46621 aatcacgccg gtagcatagg cttcattgac atgtagcccc tcacttgaca gcatatacat
    46681 atgtagggct agagaacggc ctgaagacat gagactactt ggcgtattgg tagaggtacc
    46741 taatgtatac atgagggcag ctgtttcacc aacgatacgg ccaatagcta gtatcactcc
    46801 agctaaaata cctggcatgg caactggtag aacaattcta aaaacagtcc gtaacttacc
    46861 tgccccaagt ccataacttg cttgacgcat gctatcacta acagataaaa gggcttcttc
    46921 tgttgagcga ataatgactg gcaacaccat gataactgag gttaagattc ctgataacag
    46981 agagtattga aaacctaaga agactacaaa gaagagcatg ccaaacagac caaaaacaat
    47041 ggaaggaatc ccagacaagg tatctgaggc caatcgcatg attttaacac aaagagaatc
    47101 tttttttgta tattccacaa gataaaaacc agcaaaaatc cctatgggca aggctaaaag
    47161 aagagcacca aaaaccagaa taacggtgga aataatcgct ggcataaggg aaatgttctc
    47221 agaagtataa gtccaagaaa agagggatag acttagatga ggtaagcctt tgatgaggat
    47281 aaaaccaatg attaaaaaga gagagccaaa ggttaaagct gaaaaacaat aaacgagaag
    47341 ttttagcagg tatttactca taagatgatt ttcctttcaa gtaggcaaag taggcattaa
    47401 tcaagagaat aaggaaaaag agaactgctg aggttgcaat aagggcttcc ctatgctgac
    47461 ctgatgcgta agccatttcc agaacaatat tggttgttaa ggttctggtt cctgaaaaga
    47521 gtccacttgg aataatcggc tggttgcctg ccaccaaaat aactgccatg gtttcaccta
    47581 ctgcgcgacc gattcctaaa ataactgctg ataaaatacc agatctcgca gctggcaaga
    47641 tgacactaaa aatactccgt tcatgactag ctcctagagc caagctacca gaataatacg
    47701 ttttgggaac tgttcggata gcagattctg acaaactgat aatggttggc aaaatcatta
    47761 ttcctaatag taacgaagcg gttaggacac tcatgccatt tcctaaaaag gttctaatcc
    47821 aaggcaccaa taattgtagg ccgaaaaaac cataaacaat agatggaatg gctgccatca
    47881 agttgatagc tgattttaag aagctataga cgggctttgg acaataataa accataaaca
    47941 ccgatgtcaa gatgcctgtt ggcaccccaa tcacaatcgc tcctaaggta attaataagg
    48001 aaccaacgat cattggtaaa ataccatagc ttgccggaat gttcgttggc gaccaatcac
    48061 tgcctaataa aaaacgggca aagccgtagt tagctatgaa aggtaagcca ttactaaaaa
    48121 taaagaaaca gattagcaaa atagctacaa cagctactgt tgcactcatg aaaaaaattg
    48181 ccctaaaaac tgcttctttg aaggcttgtt ttgtcacatc ttgtcctttc tagtgaagaa
    48241 agtaagggag atacgacacc tccctacttg ccttctttat cttattgtac gatgaaacgt
    48301 ctgcatctct ttagagattt atggagcaaa cattttattt aatcttgtcc caggtggtta
    48361 atttgccact aaaaacgtcc gcaagttcag ccatactgac ttggcttgcc ttattgtcat
    48421 tattgaccac aacagcaata ccgtctaaag caatagcatc atgggtgaga ctcttacctt
    48481 cttcaggagt taattcccta gaaaccatac caatatcagc ggttttctcc ttaacagcgg
    48541 taatacctgc tgaagaccca ttagaggtaa tatcaatcgt aacttctgga ttttcttttt
    48601 tataagcttc tgctaatttt tccattaaag aagatactga agtggaacct acaacagaca
    48661 acttgcctga taagtgttgg cttgtatatt ctgtggtttc ggttttagct tcaataaatt
    48721 tattatctgt gaccacttgt tgaccttgtt tggagtggat aaagctgata aaatcttgac
    48781 ctagcttgga aagattagaa gaccaaacaa tgttgaaggg acgttgaaga gggtattcac
    48841 catctaaaac tgtgtctcga ctagccttga caccatcaat ctctaaagcc ttgacagatt
    48901 tcgttaaaga tcccaaggag atgtagccga tagcattagc attcccttga actgctgaga
    48961 gaacaccttc tgtactattt tgaatcacag ctgttttggc agtgttgtca atttttttat
    49021 caccgtcttt tttgagaatc cctgtgattt ctgtgaaggc accccgtgtt ccagagccat
    49081 tttctcgtga aatcacctca atcgttcctg aagctgactg tttggaagca gctgactgat
    49141 tgccacaggc aacaagccca aatcctgata agccaatggc tgcaagagta agcatttttt
    49201 tgaatttcat aataatcacc tttatctcta tgtatttttc ttgtgtaggc ttactacatt
    49261 tatagtctaa caagtctttg taaaggttta tccctgattc atgtaaagat tgtgtaaaga
    49321 atcaaaaaaa gccacttttg aaaaatggct gctcctaaaa atagctttaa aaattattag
    49381 tcctgtgcga aagattggtt aggaagaaaa atcgtgaagc aactgcctct gccaagctga
    49441 ctcgtcaccg tgacttggcc acctaataat tgactgagtt ctttgacaat ggcaaggcca
    49501 agaccagtgc caccagtttg tctgcttcga cctttattaa ctcggtaaaa acgttcaaaa
    49561 atacgatcct gctctaattg actaatacca atccctgtat ctgatacaga aatcttaatg
    49621 ccttcgttca ccttttgggt cttgacctca atttttcccc cttgttcagt gtaacggatg
    49681 gcattggata aaagattgag taagatttgg gaaagtaatt gactatctga tacgagggtg
    49741 acatcatctg gcacctgcac ctttagctgt aaatccttct tcttgagctg aggttgcaag
    49801 ctttgagtca aatcctgtac aaattctgcc aaagaaaggg tcgtccattg tataggcatt
    49861 tgttgagcct tagataaggt aagaagatgc tcaacaatat gctcaagacg caagctttct
    49921 ttgtaaataa tgtctagaaa gtcatccttg agcgcttctt cttcagctga catcccctta
    49981 atggtttcag caaagccctt aattgaagta actggtgtcc tcaattcatg ggaggcattt
    50041 gagacaaagg ctaaatttaa cttttcataa gttctaatcg ttgttaaatc atatagcaag
    50101 acgagcacag cttccacaga ttgggtgggg ctaaaaacgg gaactgctgt cacttctaaa
    50161 atcaagtcac cctcatgaaa cccacttact tcttgtttta accttgtttt ttgatcaaag
    50221 gcttggtgaa ctaaattccg aatatccatc cgtttgaggt catcaagtga acttatgtcg
    50281 ccgtccacat cgggaaaata atgaggcaga gagcgactgg ataataacat ctgaccttga
    50341 gcggaaacta aaaacgtccc catggttagg tgcgacagaa gaacctccat tgtttcggct
    50401 aggtccttgt attgctgatc ctgttgggag actttggttt ttaggccaga cacatactta
    50461 gccaaagact ttaagtcttc ttgccctttt tctaaaaagt attcactact ggtcaagaga
    50521 ggttggtgca aggtctcaaa agcaacttcc catttccaaa ggcaaaagag ccagtagcca
    50581 cctagtccca aagaaagggc tagaagaaag agaccgatgc ctttactgat ccaagttaat
    50641 gccattcctg caatcagaat gaggctaaca cttagattga ctagccaaaa ttgaaggtag
    50701 cgtttcatct ataactcctt gaacttataa ccataacccc gaatggttcg aataaattga
    50761 ggggctttag gattgtcttc aattttttcc ctcaacttac caatatgaac gtccaccaaa
    50821 cgtgtttcct gcccaaagtc atatccccag atacgttcca aaagacgctc tctagtcagt
    50881 gtcatgttgg gatgtttcat aagatagagc aagagttcaa attcttttgg ggtcaaactc
    50941 agtaacttat tcgccttgta gacctcatga cgctcagggt atactttcaa ggtcccaaat
    51001 agccaagaat cgtcagcaat attatctgaa tcatctcctt cttgttctcc tttagttcgc
    51061 ctgaggacag ccttgacacg tgccagcaat tctctagggc taaaaggctt ggtcaggtag
    51121 tcatcagccc ctaattccaa ggccaaaacc ttatcaaatt catcactttt cgcagaaacc
    51181 atcataattg gagttttgat gcctttggct ctcagccgct tacaaacttc tatgccatct
    51241 aattgtggta acatgatatc aagcaagata aaatcaaagg gttctgtttc tgccaaagct
    51301 aaggccttcc gtccatttgt taccaattga gtagaaaagc cttccttact taaatggtag
    51361 tcaagcaatc tcagaatgtg ttcttcatca tccactaata agacttgttt tgtcatctat
    51421 tatctcctat tggtaacatt ataacacaat tatcagaaat cctaacattg ctaaatcaga
    51481 ttaaatttgc ttatcaagac tagtatctgg tcaaatgctc aatcatctcc ttgtgctctg
    51541 gataggtcgc cagtagatct gccctttcaa ataattcaaa atcctcaaat tcaaaaccag
    51601 gagcaacaag acaagaaacc agagcataat ccttatcaac tgttgatccc caaatagtgc
    51661 ccttaggaac acagtagtga agttgttgcc ctttggatat gtccaggcct aaagtgactg
    51721 cttcgtagtg accatctgct gtaatcatgt gaacagtaag tggggatcct gcatgaaaat
    51781 accagatttc atctgctgtc aatcggtgaa aatgtgaagg attcgtttct tctaataaga
    51841 aataaatact ggtataaagc gcccttcctt taccagcaag gtttatagtg tctgaagctt
    51901 tttttgtttg tctaaaatag ccaccttcaa catggggagc taactctaga gttcttatca
    51961 agtcttcttt atccgtcgga gccaatgggt tgaagtaact cttgttcaaa gtagttttac
    52021 gatttcaaga actcctctca gttctgagga cacggtaatg attgatgcga cggaagtaaa
    52081 aatcaatcgc cctaaaaaag aattagcgaa tgattctggt aaaaagaaat gccacgctat
    52141 gaaggctcaa gcgattgtca caagtcaagg gagaattgtt tctttggata tcactgtgaa
    52201 ctattgtcat gatatgaagt tgttcaaaat gagtcgcaga aatatcggac aagctggtaa
    52261 aatcttggct gacagtggtt atcaagggct tatgaagata tatcctcaag cacaaactcc
    52321 acgtaaatcc agcaaactca agccgctaac agctgaagat aaagcctgta accatgcact
    52381 atctaaggag agaagcaagg ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt
    52441 ttcaacaact tatcgaaatc atcgtaaacg cttcggatta cgaatgaatt tgattgctgg
    52501 cattatcaat catgaactag gattctagtt ttgcaggaag tctattattt ggttaggtga
    52561 attagtgaag cgtttaggca agtgtctctg gttacgacgt aaagaagcat aaatcgataa
    52621 tatttatgtt tctttactag tgaaacgcct agccaaatta ccatagttac gacgtcatgg
    52681 cctctaaatc gattatattt aggggtcatg actagtgaag cagttagcta gttcgcatat
    52741 aagcggctag cgtctaacaa ttaggaactt tagttccaat aactttaaga ttacgacgtt
    52801 ttaggacata aatcgatcat atttatgtcc taaaactagt gaagcgccta gccaaagtcc
    52861 gaataggatt tggcgttagt tacttagatt gctttgcaat caagtaactt tggcgattta
    52921 catcttctct ggcgcttcta ctccaagcaa gcgaagggct tctttgagaa cgactgcggt
    52981 tgcgtagctg agggctagac ggctgtcgcg ttctgggctt tcatccaaga tacgtgtatg
    53041 tgcatagtat ttgttaaagg attgagctag gctaattgca aatttagcaa tgatagaagg
    53101 ttcaaagtta tctgccgcac ggttgataat acgtgggaag tcttgaatga gtttaatgat
    53161 ttcccagctt tcagtatcat tcaagctata gttgccagct gtttctggtt tgaaatcggc
    53221 tttgcgtaag atagattgga tacgagcgta ggcatattga acgtaaggtc cagtttcacc
    53281 ctcgaaggat accatagcct ctaggtcgaa gtcgtatcca tttgtacggt cggttttgag
    53341 gtcatagaat ttaatggctc caaccccaac agcatgtgct acttggtctt tgttttctag
    53401 ttcaggattt ttagcctcga tttggacctt ggcacggcta acagcctctg caacagtagg
    53461 ctctagcaag atgacattcc ctttacgagt agagagtttc ttcccttctt ttgtaaccaa
    53521 accaaaagga acgtgagtaa tgtcgtcact ccagtcgtag cccatctctt gcaagacagc
    53581 tttgagctgt ttaaagtggg cagattgttc ttgaccaacg acatagatag atttagcaaa
    53641 ttggtattcg tttttacggt aaagggctgc agccaagtca cgtgtgatat agagagttgc
    53701 accatcagat ttcttgatga gagctggatg ttcaattccg tatttctcaa gattgacaac
    53761 ttgggcacct tctgattcaa gaagtagtcc tttttcagaa agaatgtcta caactgcatc
    53821 catcttatca ttgtagaagg cttctccgtt atagctgtca aattcaacct tcaattcatt
    53881 gtaaaggcgg ttaaattcca ctaaactttc atcgcggaac cattgccaaa gagcgagagc
    53941 ttcctcatct ccattttcaa gtttacggaa ccattcgcgc gcttcttcat ccaagctagg
    54001 gtcattttca gcttcagcgt tgatgcggac atagagttta aggagttcat cgattggatg
    54061 agcttttaca gcttcttcgt cgccccattt tttgtaggca acaatcaaca tcccaaattg
    54121 tttaccccag tctcccaaat ggttgacctt gaccgtttga taaccgattt tttggaaaat
    54181 atgtgacaag ctatctccga taacagttga acgcaggtgg ccaatagaaa atggtttagc
    54241 gatattcgga ctagacatgt cgataacaac attttcttgt ttaccaatat tttggtcagc
    54301 atagtgttct ttttcagtgg taacagcttg caatacttga gcagaaatgg cagatttatc
    54361 aaggaaaaag ttaacgtaag gtcctgttgc gacaactttt tcaaaggctt ggctgttcat
    54421 tttttcagcc agttcagccg caatcatttg tggtgcttta cgttcgactt tggcaagaga
    54481 aaaagcaggg aaagcgatgt cacccatttc tgagttttta ggggtttcca gtaactttaa
    54541 aatagcctct tggtccaggc tatcaatgat gctagccaat tcgctagcaa tcaattcttt
    54601 tgtattcatt aagagctcct ttttggactt ttctactatt ttatcacaat tttaaagaaa
    54661 gaagaaaaaa tttttgaaat ctcctgtttt tttggtataa tatggttata aatatagtta
    54721 taaatatgca cgcaagagga ttttatgaga aaaagagatc gtcatcagtt aataaaaaaa
    54781 atgattactg aggagaaatt aagtacacaa aaagaaattc aagatcggtt ggaggcgcac
    54841 aatgtttgtg tgacgcagac aaccttgtct cgtgatttgc gcgaaatcgg cttgaccaag
    54901 gtcaagaaaa atgatatggt gtattatgta ctagtaaatg agacagaaaa gattgatttg
    54961 gtggaatttt tgtctcatca tttagaaggt gttgcaagag cagagtttac cttggtgctt
    55021 cataccaaat tgggagaagc ctctgttttg gcaaatattg tagatgtaaa caaggatgaa
    55081 tggattttag gaacagttgc tggtgccaat accttattgg ttatttgtcg agatcagcac
    55141 gttgccaaac tcatggaaga tcgtttgcta gatttgatga aagataagta aggtcttggg
    55201 agttgctctc aagacttatt tttgaaaagg agagacagaa aatggcgata gaaaagctat
    55261 cacccggcat gcaacagtat gtggatatta aaaagcaata tccagatgct tttttactct
    55321 ttcggatggg tgatttttat gaattatttt atgaggatgc ggtcaatgct gcgcagattc
    55381 tggaaatttc cttaacgagt cgcaacaaga atgccgacaa tccgatccct atggcgggtg
    55441 ttccctatca ttctgcccaa cagtatatcg atgtcttgat tgagcagggt tataaggtgg
    55501 ctatcgcaga gcagatggaa gatcctaaac aagcagttgg ggttgttaaa cgagaggttg
    55561 ttcaggtcat tacgccaggg acagtggtcg atagcagtaa gccggacagt cagaataatt
    55621 ttttggttgc catagaccgc gaaggcaatc aatttggtct agcttatatg gatttggtga
    55681 cgggtgactt ttatgtgaca ggtcttttgg atttcacgct ggtttgtggg gaaatccgta
    55741 acctcaaggc tcgagaagtg gtgttgggtt atgacttgtc tgaggaagaa gaacaaatcc
    55801 tcagccgcca gatgaatctg gtactctctt atgaaaaaga aagctttgaa gaccttcatt
    55861 tattggattt gcgattggca acggtggagc aaacggcatc tagtaagctg ctccagtatg
    55921 ttcatcggac tcagatgagg gaattgaacc acctcaaacc tgttatccgc tacgaaatta
    55981 aggatttctt gcagatggat tatgcgacca aggctagtct ggatttggtt gagaatgctc
    56041 gctcaggtaa gaaacaaggc agtcttttct ggcttttgga tgaaaccaaa acggctatgg
    56101 ggatgcgtct cttgcgttct tggattcatc gccccttgat tgataaggaa cgaatcgtcc
    56161 aacgtcaaga agtggtgcag gtctttctcg accatttctt tgagcgtagt gacttgacag
    56221 acagtctcaa gggtgtttat gacattgagc gcttggctag tcgtgtttct tttggcaaaa
    56281 ccaatccaaa ggatctcttg cagttggcga ctaccttgtc tagtgtgcca cggattcgtg
    56341 cgattttaga agggatggag caacctgctc tagcctatct cattgcacaa ctggatgcaa
    56401 tccctgagtt ggagagtttg attagcgcag cgattgctcc tgaagctcct catgtgatta
    56461 cagatggggg aattatccgg actggatttg atgagacttt agacaagtat cgttgcgttc
    56521 tcagagaagg gactagctgg attgctgaga ttgaggctaa ggagcgagaa aactctggta
    56581 tcagcacgct caagattgac tacaataaaa aggatggcta ctattttcat gtgaccaatt
    56641 cgcaactggg aaatgtgcca gcccactttt tccgcaaggc gacgctgaaa aactcagaac
    56701 gctttggaac cgaagaatta gcccgtatcg agggagatat gcttgaggcg cgtgaggagt
    56761 cagccaacct cgaatacgaa atatttatgc gcattcgtga agaggtcggc aagtacatcc
    56821 agcgtttaca agctctagcc caaggaattg cgacggttga tgtcttacag agtctggcgg
    56881 ttgtggctga aacccagtat ttgattcgac ctgagtttgg tgacgattca caaattgata
    56941 ttcggaaagg gcgccatgct gtcgttgaaa aggttatggg ggctcagacc tatattccaa
    57001 atacgattca gatggcagaa gataccagta ttcaactgat tacagggcca aacatgagtg
    57061 ggaagtctac ctatatgcgt cagttagcca tgacggcggt tatggcccag ctgggttcct
    57121 atgttcctgc tgaaagcgcc catttaccga tttttgatgc gatttttacc cgtatcggag
    57181 cagcagatga cttggtttcg ggtcagtcaa cctttatggt ggagatgatg gaggccaata
    57241 atgccatttc gcatgcgacc aagaactctc tcattctctt tgatgaattg ggacgtggaa
    57301 ctgcaactta tgacgggatg gctcttgctc agtccatcat cgaatatatc catgagcaca
    57361 tcggagctaa gaccctcttt gcgacccact accatgagtt gactagtctg gagtctagtt
    57421 tacaacactt ggtcaatgtc cacgtggcaa ctttggagca ggatgggcag gtcaccttcc
    57481 ttcacaagat tgaaccggga ccagctgata aatcctacgg tatccatgtt gccaagattg
    57541 ctggcttgcc agcagacctt ttagcaaggg cggataagat tttgactcag ctagagaatc
    57601 aaggaacaga gagtcctcct cccatgagac aaactagtgc tgtcactgaa cagatttcac
    57661 tctttgatag ggcagaagag catcctatcc tagcagaatt agctaaactg gatgtgtata
    57721 atatgacacc tatgcaggtt atgaatgtct tagtagagtt aaaacagaaa ctataaaacc
    57781 aagactcact agttaatcta gctgtatcaa ggagacttct ttgacaattc tccacttttt
    57841 tgctagaata acatcacaca aacagaatga aaaggagctg acgcattgtc gctccctttt
    57901 gtctattttt taaggagaaa gtatgctgat tcagaaaata aaaacctaca agtggcaggc
    57961 cctggcttcg ctcctgatga caggcttgat ggttgctagt tcacttctgc aaccgcgtta
    58021 tctgcaggaa gtcttaggcg ccctccttac tgggaaatat gaagctattt atagtatcgg
    58081 ggcttggttg attggtgtgg ccgtagtcgg tctagttgct ggtggactca atgttgtcct
    58141 cgcagcctat attgcccaag gagtttcatc cgaccttcgg gaggatgcct tccgtaaaat
    58201 tcaaaccttt tcttatgctg atattgaaca atttaatgcg ggaaatctag tcgttcgaat
    58261 gacaaatgat atcaaccaga ttcagaacgt tgtcatgatg accttccaaa ttcttttcag
    58321 acttcccctc ttgttcatcg gttcgtttat cctagcggtt caaaccttac cttctctgtg
    58381 gtgggtgatt gttctcatgg tagtcttgat ttttggtttg actgctgtca tgatgggaat
    58441 gatggggcct cgttttgcta aatttcaaac ccttcttgag cgcatcaatg ccattgccaa
    58501 ggaaaattta cgtggcgttc gtgtggtcaa gtcctttgtc caagaaaaag agcaatttgc
    58561 taagtttaca gaggtctcaa acgagcttct tggtcaaaac ctttacattg gttatgcctt
    58621 ttcagtagtg gaacccttta tgatgttggt tggttacggg gcggtcttcc tctctatttg
    58681 gctggtcgcg ggaatggttc agtcggatcc gtctgttgtt ggttccatcg cttcttttgt
    58741 taattaccta agccagatta tctttaccat tgttatggtt ggatttttgg gaaattctgt
    58801 cagccgtgcc atgatttcca tgcgtcgtat tcgagaaatt cttgacgcag agccagctat
    58861 gaccttcaag gatatcccag atgaagagtt ggttggaagt cttagctttg aaaatgtgac
    58921 ctttacctat ccaatggaca aggaaccgat gctgaaagat gtgagcttta ctattgaacc
    58981 tggtcaaatg gttggtgtag ttggagcgac tggtgcagga aagtcaacct tggctcaatt
    59041 gattccacgt ctctttgatc cacaggacgg ggccattaaa atcggtggca aggatattcg
    59101 agaagtgagt gaaggaaccc tgcgtaaaac agtttccatc gttctccaac gtgccattct
    59161 ttttagtgga acgattgcag ataacttgag acaggggaag ggaaatgcta ctctatttga
    59221 aatggagcgc gcagccaata ttgcccaggc tagtgaattc attcatcgta tggagaaaac
    59281 ctttgaaagt ccagttgaag aacggggaac caatttctct ggtggacaaa aacaaaggat
    59341 gtcgattgcg cgtgggattg tcagcaatcc acgtattctg atttttgacg attcgacctc
    59401 agccttggat gccaaatcag agcgcttggt gcaagaagct ttgaataagg acttgaaggg
    59461 gacgacaacc attattattg ctcaaaaaat tagctcggtt gtccatgcag acaagatctt
    59521 ggttctaaat caaggacgat tgattggtca aggcacgcat gcagacttgg ttgccaacaa
    59581 tgccgtttac cgtgaaatct atgaaacaca gaaatgaaag acaaactata agaaaagtca
    59641 atagttttat ctaaactatt tcttatttca atttgatgat ttggcgatga ttttagagca
    59701 cggcaaaaag cccttgaaaa agtccatttt ttcaaaggta atcctgtgtt gatttcagaa
    59761 attacatcac tttttgttcg tcaaatggca gctctttttt aggatataaa acagggttcg
    59821 gataagtttt tttgcaaggt ggatgatggc tacattgtaa tgttttcctt gttctaactt
    59881 agtcttaaaa gcaggtgaaa agtgagggca tgctttggca gcttgtatga gtacctaccg
    59941 cagatgaggg gaaccccgtt tgaccattct tccagctaaa tcaatctgac ctgactgata
    60001 aatagaagaa tccagtccag cgaaagcttg taattgagca ggattatcaa aggcatgaat
    60061 atttcgaatc tcggctaaaa tgaccgcccc taaacgattc tcaatcccag taaccgtcgt
    60121 gatgaccgag tttaactcag ccatcaagtc attgacacat ttttccgcct tgtcaatgag
    60181 cctcttgtaa tgtttgatgt tttcattaca cgagataaaa cgtctatgcg ttatcaaact
    60241 cattaccaat taaaacaaat gtggttagat cctttcggaa attgtcaagc gattggagga
    60301 aatgaactaa tccacagcgg cttattccaa gtataccact tgggctttgg cagtagctaa
    60361 ctgcgctaaa tataatataa ggaggagtaa aatgaagaca gttcaatttt tttggcatta
    60421 ttttaaggtc tacaagttct catttgtagt tgtcatcctg atgattgttc tggcgacttt
    60481 tgcccaagcc ctctttccag tcttttctgg acaagcggtg acgcagctag ccaatttagt
    60541 tcaagcttat caaaatggca atccagaact tgtatggcaa agcctatcag gaatcatggt
    60601 caatcttggc ctgctggttt tggttctatt tatctctagt gtaatataca tgtgtctcat
    60661 gacgcgcgtg attgcagaat cgaccaacga gatgcgcaaa ggtctctttg gtaagcttgc
    60721 tcagttgacg gtttctttct ttgaccgtcg acaagatggc gatatcctgt ctcattttac
    60781 cagtgatttg gataatatcc tccaagcctt taacgaaagc ttgattcagg tcatgagcaa
    60841 tattgtttta tacattggtc tgattcttgt catgttttcg agaaatgtga cgctggctct
    60901 catcaccatt gccagcaccc cattggcttt ccttatgctg attttcatcg tgaaaatggc
    60961 acgtaaatac accaacctcc agcagaaaga ggtagggaag ctcaacgcct atatggatga
    61021 gagcatctca ggccaaaaag ccgtgattgt gcaaggaatt caagaggata tgatggcagg
    61081 atttcttgaa caaaatgagc gcgtgcgcaa ggcaaccttt aaaggaagaa tgttctcagg
    61141 aattcttttc cctgtcatga atgggatgag cctgattaat acagccatcg tcatctttgc
    61201 tggttcggct gtacttttga atgataagtc tattgaaaca agtacagccc taggtttgat
    61261 tgttatgttt gcacaatttt cacagcagta ctaccagcct attatccaag ttgcagcgag
    61321 ttggggaagc cttcagttgg cctttactgg agctgaacga attcaggaaa tgtttgatgc
    61381 agaggaggaa atccgacctg aaaaggctcc aaccttcact aagttgcaag aaagtgttga
    61441 aatcagtcat atcgattttt catacttgcc tgataaacct attttgaaag atgtcagcat
    61501 ttctgcccct aaaggccaga tgacagcagt tgttgggccg acaggttcag gaaaaacgac
    61561 tattatgaac ctcatcaatc gcttttatga tgttgatgct ggtggtattt attttgatgg
    61621 taaagacatt cgtggctatg acttagatag tcttagaagc aaggtgggaa ttgtattgca
    61681 agattcggtc ttgtttagcg gaacgattcg agacaatatc cgatttggtg tgccagatgc
    61741 tagtcaggaa atggttgagg tagcagcaaa agcaacccac attcacgact atatcgaaag
    61801 tttgcctgat aagtacgata ctcttattga tgatgaccag agcatctttt caacagggca
    61861 gaagcaattg atttcaatcg ctcgaaccct gatgacagat ccagaagttc tcattctcga
    61921 tgaagcaact tcaaacgtag atacggtgac agaaagcaag attcagcatg ccatggaggt
    61981 ggttgtagca ggtagaacta gtttcgtcat tgcccaccgc ttgaaaacca ttctcaatgc
    62041 agatcagatt attgtcctta aagatggaga agtcattgaa cgtggtaacc accatgaact
    62101 tttgaagcta ggtggctttt attcagaact ctatcacaat caatttgttt tcgaataaga
    62161 aagaagttgt cctatgtggg cagctttttc ttgtccataa aaaatgttta tcacagcctt
    62221 aaaaaaaaca tattagacga aagtcatttt gagtgatatg ataggactat cgttagcatt
    62281 cgaaaggaga ggcatcatgg ctagaacggt tgtaggagtt gctgcaaatc tatgtcccgt
    62341 agacgcagaa ggcaaaatca ttcattcatc tgtatcttgt agattcgcag agatcattcg
    62401 tcaagtcggt ggtctccctt tagtcattcc tgttggtgat gagtcagttg tacgtgatta
    62461 tgtggaaatg attgacaaac tcattttgac aggaggccaa aatgttcatc ctcagtttta
    62521 tggagagaaa aagaccgtcg agagcgatga ttacaatctg gtccgtgacg aatttgaatt
    62581 ggcactcttg aaggaagcgc ttcgtcagaa taaaccaatt atggcaatct gtcgcggtgt
    62641 ccaacttgtc aatgttgcct ttggtggaac cctcaatcaa gaaatcgaag gtcactggca
    62701 aggactacct ttcgggacat ctcactctat tgagacagta gaaggaagcg tggtggctaa
    62761 gctctttggg aaagaaagtc aggtcaactc agtccatcgt caaagcatta aagatttggc
    62821 acctaatttc cgtgtaactg ctattgattc aagagaccaa actattgaag cgattgagtc
    62881 tatcgacgag caccgcatta tcggtttaca gtggcatcca gagtttctgg ttaatgaaga
    62941 agatggcaat ttagaattat ttgagtattt attgaatgaa ctgtaacgat tggaacatct
    63001 ggtcgttctt tcttttattt tttcaaaatt tttagaatgt ggtattttac gcaaacgttt
    63061 gaattctgat aaaaattgga gaaattcgac aagaaaactt gaaaaaaacg aaggtaagcg
    63121 ttatgataga aaagaagaaa tattggagga agaacatgtc acatattaaa tttgattatt
    63181 caaaagtttt agacaaattt gttgcaccac atgaagtgga atacatgcaa tcacaagtaa
    63241 cagcagcaga tgaattgatc cgtaaaggaa ctggtgctgg tagcgacttc ttgggatggt
    63301 tggaccttcc tgaaaaatac gatcgcgaag aatttgaccg catcttgaaa gctgctgagc
    63361 aaatcaagtc agacagcgat gttttggttg tgatcggtat tggtggatct taccttggtg
    63421 caaaagcagc aatcgacttc ttgaatcacc attttgctaa cttgcaaaca aaagaagaac
    63481 gcaaagctcc acaaatcctt tacgcaggaa actcaatctc atctacttac cttgctgact
    63541 tggtagagta tgttgcagac aaagacttct cagtaaacgt aatttctaaa tcaggtacaa
    63601 caactgaacc agcgattgct ttccgtgtct ttaaagaact cttggttaag aaatacggtc
    63661 aagaagaagc taacaaacgt atctatgcaa caactgaccg ccaaaagggt gctgttaagg
    63721 ttgaagcaga cgctaacggt tgggaaacat ttgttgttcc agatgatatc ggtggacgct
    63781 tctcagtatt gacagccgtt ggtttgcttc caatcgcagc atcaggagct gacatcaaag
    63841 ctcttatgga aggtgcgaat gcagctcgca aagactacac ttcagacaaa atctctgaaa
    63901 acgaagctta ccaatacgca gctgttcgta acatccttta tcgtaaaggc tatgcaactg
    63961 agatcttggt aaactatgag ccatcacttc aatacttctc agaatggtgg aaacaattgg
    64021 ctggtgaatc agaaggaaaa gacaaaaaag gtatctaccc aacttcagcc aacttctcaa
    64081 ctgacttgca ctcacttggt caatttatcc aagaaggaac tcgtatcatg tttgaaacag
    64141 ttgtccgtgt tgacaaacct cgtaaaaacg tgcttattcc tactttggaa gaagaccttg
    64201 acggacttgg ttaccttcaa ggaaaagacg ttgactttgt aaacaaaaaa gcaactgacg
    64261 gtgttcttct tgcccacaca gatggtgatg taccaaacat gtatgtgact cttccagagc
    64321 aagacgcttt cactcttggt tacactatct acttcttcga attggcaatt gccctttcag
    64381 gttacttgaa tgctatcaac ccatttgacc aaccaggtgt tgaagcttat aaacgtaaca
    64441 tgtttgccct tcttggaaaa ccaggatttg aagaattgag caaagaactt aacgcacgtc
    64501 tataatagaa gaaaagagtg gtttgcccac tctttttact ctctttatcc atagaaattg
    64561 gactcagcca agacttgtga tataatatag aaagcaaaaa ggcagacgcc tagataatag
    64621 gagaaactat gtcaaaagat atccgcgtac gttacgcacc aagtccaaca ggactactac
    64681 acatcggaaa tgcccgtaca gcattgttta actacttgta tgcgcgccat catggtggaa
    64741 catttctcat ccgtatcgaa gatactgacc gtaaacgcca tgtcgaggat ggtgaacgtt
    64801 cacaacttga aaaccttcgc tggttaggca tggattggga tgaaagtcca gaatcacatg
    64861 agaattatcg ccagtctgag cgtttggact tgtatcaaaa atacattgac caactattag
    64921 ctgaaggaaa agcctataaa tcttacgtta cagaagaaga gttggcagct gaacgtgaac
    64981 gtcaagaagc tgctggtgaa acacctcgat atatcaacga ataccttggt atgagtgaag
    65041 aggaaaaagc ggcttatatc gcagaacgtg aagcagctgg tatcatacca acagttcgtt
    65101 tggctgtcaa tgagtcaggt atctacaagt ggcatgatat ggtcaaaggt gatatcgaat
    65161 ttgaaggtgg caatatcggc ggtgactggg ttatccaaaa gaaagacggt tacccaactt
    65221 acaactttgc cgttgttatc gatgaccacg atatgcaaat ctctcatgtt atccgtggag
    65281 atgaccatat tgctaataca ccaaaacagc ttatggtcta tgaagctctt ggttgggaag
    65341 ctccagagtt tggtcacatg accttgatta tcaactctga gactggtaag aagttatcta
    65401 aacgtgatac taatacactt caatttatcg aagattaccg aaagaaaggt taccttccag
    65461 aagcagtctt taactttatt gctcttcttg gttggaaccc aggtggtgaa gatgagattt
    65521 tctctcgtga agaactcatt aaactttttg atgaaaaccg cctcagcaag tcaccagcag
    65581 cctttgatca gaaaaaacta gactggatga gcaatgatta tatcaagaat gcagaccttg
    65641 aaaccatctt tgaaatggca aaaccattct tagaggaagc aggccgtttg actgacaagg
    65701 ctgaaaaatt agttgagctc tataaaccac aaatgaaatc agtagatgag attatcccat
    65761 tgacagatct tttcttctca gatttcccag aattgacaga agcagagcgc gaagtcatga
    65821 cgggtgaaac agttccaaca gttcttgaag cattcaaagc aaaacttgaa gcgatgacag
    65881 atgatgaatt tgtgacagaa aatatcttcc cgcaaattaa agcagtccaa aaagaaacag
    65941 gtattaaagg gaaaaatctt ttcatgccta ttcgtatcgc agtttcaggc gaaatgcatg
    66001 ggccagaatt accagataca attttcttgc ttggacgtga aaaatcaatt cagcatatcg
    66061 aaaacattct aaaagaaatc tctaaataaa gaggatacaa taatggacat ctgggaaaag
    66121 atgtacgaag aagcacagaa actatacaat ccacatgaag tatcagactt tgtttatgcc
    66181 aatcatgttg tagctgcagt agaagcagga gatggacaaa tatttacagg attctgtatg
    66241 gagggaacct gtggtgtttt ccatctctgc gcagaacggg cggccctctt caatatgtac
    66301 caattttcag gacaaactaa ggttaagaaa gtattagcct ttcgagacaa accaccttat
    66361 ggtggaagtt cagccatgcc ttgcggtgct tgtagagaat tccttttaga gcttaatgct
    66421 gaaaataaag atgcagaatt catgatggac tataatataa gaaaaacagt taaagtcgca
    66481 gaactaatcc cttattggtg gggaaaagaa cgtgcttcta agtttaatga gcgatagaag
    66541 agtcagtata attctggctc tttttactat aag
//
LOCUS       DAVKAU010000005        64332 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVKAU010000005 DAVKAU010000000
VERSION     DAVKAU010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64332
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.005"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(59..130)
                     /locus_tag="VWX48_000361"
     tRNA            complement(59..130)
                     /locus_tag="VWX48_000361"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(95..97),aa:Glu,seq:ttc)
     gene            complement(224..703)
                     /locus_tag="VWX48_000362"
     CDS             complement(224..703)
                     /locus_tag="VWX48_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU9171053.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            complement(825..2783)
                     /gene="ftsH"
                     /locus_tag="VWX48_000363"
     CDS             complement(825..2783)
                     /gene="ftsH"
                     /locus_tag="VWX48_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU9171054.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2799..3341)
                     /gene="hpt"
                     /locus_tag="VWX48_000364"
     CDS             complement(2799..3341)
                     /gene="hpt"
                     /locus_tag="VWX48_000364"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU9171055.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(3345..4622)
                     /gene="tilS"
                     /locus_tag="VWX48_000365"
     CDS             complement(3345..4622)
                     /gene="tilS"
                     /locus_tag="VWX48_000365"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU9171056.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(4619..5887)
                     /locus_tag="VWX48_000366"
     CDS             complement(4619..5887)
                     /locus_tag="VWX48_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU9171057.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(6007..6375)
                     /locus_tag="VWX48_000367"
     CDS             complement(6007..6375)
                     /locus_tag="VWX48_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU9171058.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(6368..6634)
                     /locus_tag="VWX48_000368"
     CDS             complement(6368..6634)
                     /locus_tag="VWX48_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU9171059.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6692..10201)
                     /gene="mfd"
                     /locus_tag="VWX48_000369"
     CDS             complement(6692..10201)
                     /gene="mfd"
                     /locus_tag="VWX48_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU9171060.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTKVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(10202..10771)
                     /locus_tag="VWX48_000370"
     CDS             complement(10202..10771)
                     /locus_tag="VWX48_000370"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU9171061.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10842..11957)
                     /gene="ychF"
                     /locus_tag="VWX48_000371"
     CDS             complement(10842..11957)
                     /gene="ychF"
                     /locus_tag="VWX48_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU9171062.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(12041..12235)
                     /locus_tag="VWX48_000372"
     CDS             complement(12041..12235)
                     /locus_tag="VWX48_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU9171063.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(12300..13436)
                     /gene="dnaN"
                     /locus_tag="VWX48_000373"
     CDS             complement(12300..13436)
                     /gene="dnaN"
                     /locus_tag="VWX48_000373"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU9171064.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IEAVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(13595..14956)
                     /gene="dnaA"
                     /locus_tag="VWX48_000374"
     CDS             complement(13595..14956)
                     /gene="dnaA"
                     /locus_tag="VWX48_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU9171065.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(15169..15927)
                     /locus_tag="VWX48_000375"
     CDS             complement(15169..15927)
                     /locus_tag="VWX48_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU9171066.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15985..17166)
                     /locus_tag="VWX48_000376"
     CDS             complement(15985..17166)
                     /locus_tag="VWX48_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU9171067.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            17349..17828
                     /gene="rlmH"
                     /locus_tag="VWX48_000377"
     CDS             17349..17828
                     /gene="rlmH"
                     /locus_tag="VWX48_000377"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU9171068.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17872..17945
                     /locus_tag="VWX48_000378"
     tRNA            17872..17945
                     /locus_tag="VWX48_000378"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17906..17908,aa:Arg,seq:tct)
     gene            18111..18236
                     /gene="comC"
                     /locus_tag="VWX48_000379"
     CDS             18111..18236
                     /gene="comC"
                     /locus_tag="VWX48_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU9171069.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            18257..19582
                     /locus_tag="VWX48_000380"
     CDS             18257..19582
                     /locus_tag="VWX48_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9171070.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            19579..20331
                     /locus_tag="VWX48_000381"
     CDS             19579..20331
                     /locus_tag="VWX48_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9171071.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            20383..20454
                     /locus_tag="VWX48_000382"
     tRNA            20383..20454
                     /locus_tag="VWX48_000382"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20416..20418,aa:Glu,seq:ttc)
     gene            20460..20533
                     /locus_tag="VWX48_000383"
     tRNA            20460..20533
                     /locus_tag="VWX48_000383"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20494..20496,aa:Asn,seq:gtt)
     gene            complement(20574..21116)
                     /locus_tag="VWX48_000384"
     CDS             complement(20574..21116)
                     /locus_tag="VWX48_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU9171072.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            21295..22062
                     /locus_tag="VWX48_000385"
     CDS             21295..22062
                     /locus_tag="VWX48_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEU9171073.1"
                     /translation="MIGISLIPALYNIIFLSSMWEPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDQLVSGSNTLTQKSSRLTAGVG"
     gene            22147..22485
                     /locus_tag="VWX48_000386"
     CDS             22147..22485
                     /locus_tag="VWX48_000386"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171074.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            22513..22827
                     /locus_tag="VWX48_000387"
     CDS             22513..22827
                     /locus_tag="VWX48_000387"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU9171075.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22928..25480)
                     /locus_tag="VWX48_000388"
     CDS             complement(22928..25480)
                     /locus_tag="VWX48_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU9171076.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDIALRNILHGNSSLVYTFTSGLGLNFYALSSYYLGSFLSPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGIASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGITKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(25542..27164)
                     /locus_tag="VWX48_000389"
     CDS             complement(25542..27164)
                     /locus_tag="VWX48_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9171077.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIHSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            27370..28395
                     /gene="trpS"
                     /locus_tag="VWX48_000390"
     CDS             27370..28395
                     /gene="trpS"
                     /locus_tag="VWX48_000390"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU9171078.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            28547..30025
                     /gene="guaB"
                     /locus_tag="VWX48_000391"
     CDS             28547..30025
                     /gene="guaB"
                     /locus_tag="VWX48_000391"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU9171079.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(30076..31173)
                     /gene="recF"
                     /locus_tag="VWX48_000392"
     CDS             complement(30076..31173)
                     /gene="recF"
                     /locus_tag="VWX48_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU9171080.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(31176..31544)
                     /gene="yaaA"
                     /locus_tag="VWX48_000393"
     CDS             complement(31176..31544)
                     /gene="yaaA"
                     /locus_tag="VWX48_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU9171081.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            31703..32953
                     /locus_tag="VWX48_000394"
     CDS             31703..32953
                     /locus_tag="VWX48_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9171082.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPPLFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32950..34233
                     /locus_tag="VWX48_000395"
     CDS             32950..34233
                     /locus_tag="VWX48_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9171083.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDCFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESMSQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            34275..35096
                     /locus_tag="VWX48_000396"
     CDS             34275..35096
                     /locus_tag="VWX48_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9171084.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            35107..35652
                     /gene="pgsA"
                     /locus_tag="VWX48_000397"
     CDS             35107..35652
                     /gene="pgsA"
                     /locus_tag="VWX48_000397"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU9171085.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            35649..36476
                     /locus_tag="VWX48_000398"
     CDS             35649..36476
                     /locus_tag="VWX48_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9171086.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPV
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            36461..37300
                     /locus_tag="VWX48_000399"
     CDS             36461..37300
                     /locus_tag="VWX48_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9171087.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            37293..38087
                     /locus_tag="VWX48_000400"
     CDS             37293..38087
                     /locus_tag="VWX48_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9171088.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            38146..38964
                     /gene="mreC"
                     /locus_tag="VWX48_000401"
     CDS             38146..38964
                     /gene="mreC"
                     /locus_tag="VWX48_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU9171089.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVVDIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38964..39458
                     /gene="mreD"
                     /locus_tag="VWX48_000402"
     CDS             38964..39458
                     /gene="mreD"
                     /locus_tag="VWX48_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU9171090.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            39552..40730
                     /locus_tag="VWX48_000403"
     CDS             39552..40730
                     /locus_tag="VWX48_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU9171091.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAERATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40954..41733
                     /gene="rpsB"
                     /locus_tag="VWX48_000404"
     CDS             40954..41733
                     /gene="rpsB"
                     /locus_tag="VWX48_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU9171092.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41812..42852
                     /locus_tag="VWX48_000405"
     CDS             41812..42852
                     /locus_tag="VWX48_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU9171093.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            43098..43421
                     /gene="tnpB"
                     /locus_tag="VWX48_000406"
     CDS             43098..43421
                     /gene="tnpB"
                     /locus_tag="VWX48_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9171094.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPKI"
     gene            complement(43576..43863)
                     /locus_tag="VWX48_000407"
                     /pseudo
     CDS             complement(43576..43863)
                     /locus_tag="VWX48_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43854..44252
                     /locus_tag="VWX48_000408"
     CDS             43854..44252
                     /locus_tag="VWX48_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9171095.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(44449..45369)
                     /gene="cysK"
                     /locus_tag="VWX48_000409"
     CDS             complement(44449..45369)
                     /gene="cysK"
                     /locus_tag="VWX48_000409"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU9171096.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLVLAPDNGERYLSTALYEL"
     gene            complement(45654..46289)
                     /locus_tag="VWX48_000410"
     CDS             complement(45654..46289)
                     /locus_tag="VWX48_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU9171097.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            46345..47643
                     /locus_tag="VWX48_000411"
     CDS             46345..47643
                     /locus_tag="VWX48_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9171098.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            47640..48302
                     /locus_tag="VWX48_000412"
     CDS             47640..48302
                     /locus_tag="VWX48_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU9171099.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSIKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            48382..48930
                     /gene="raiA"
                     /locus_tag="VWX48_000413"
     CDS             48382..48930
                     /gene="raiA"
                     /locus_tag="VWX48_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU9171100.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            49066..51039
                     /locus_tag="VWX48_000414"
     CDS             49066..51039
                     /locus_tag="VWX48_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU9171101.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFIANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            51036..51488
                     /gene="rplI"
                     /locus_tag="VWX48_000415"
     CDS             51036..51488
                     /gene="rplI"
                     /locus_tag="VWX48_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU9171102.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            51532..52884
                     /gene="dnaB"
                     /locus_tag="VWX48_000416"
     CDS             51532..52884
                     /gene="dnaB"
                     /locus_tag="VWX48_000416"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU9171103.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            52886..53152
                     /locus_tag="VWX48_000417"
     CDS             52886..53152
                     /locus_tag="VWX48_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171104.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            53241..54359
                     /gene="cbpD"
                     /locus_tag="VWX48_000418"
     CDS             53241..54359
                     /gene="cbpD"
                     /locus_tag="VWX48_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU9171105.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNYQNQSGNISSYGSNNSSTV
                     GWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQTGWLKENGSWYYLGSSGAM
                     KTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      54442..54544
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            54616..54906
                     /locus_tag="VWX48_000419"
     CDS             54616..54906
                     /locus_tag="VWX48_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU9171106.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            54869..55627
                     /locus_tag="VWX48_000420"
     CDS             54869..55627
                     /locus_tag="VWX48_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9171107.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            55666..56673
                     /locus_tag="VWX48_000421"
     CDS             55666..56673
                     /locus_tag="VWX48_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9171108.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            56673..57401
                     /locus_tag="VWX48_000422"
     CDS             56673..57401
                     /locus_tag="VWX48_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171109.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AETISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            57520..57978
                     /locus_tag="VWX48_000423"
     CDS             57520..57978
                     /locus_tag="VWX48_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU9171110.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLVSVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            57980..60412
                     /locus_tag="VWX48_000424"
     CDS             57980..60412
                     /locus_tag="VWX48_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9171111.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVSAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESSLIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            60733..61386
                     /gene="rr06"
                     /locus_tag="VWX48_000425"
     CDS             60733..61386
                     /gene="rr06"
                     /locus_tag="VWX48_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU9171112.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            61383..62714
                     /gene="hk06"
                     /locus_tag="VWX48_000426"
     CDS             61383..62714
                     /gene="hk06"
                     /locus_tag="VWX48_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU9171113.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLLNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            62797..63324
                     /locus_tag="VWX48_000427"
     CDS             62797..63324
                     /locus_tag="VWX48_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU9171114.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            63424..63555
                     /locus_tag="VWX48_000428"
                     /pseudo
     CDS             63424..63555
                     /locus_tag="VWX48_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            63602..>64332
                     /locus_tag="VWX48_000429"
     CDS             63602..>64332
                     /locus_tag="VWX48_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HEU9171115.1"
                     /translation="MFASKSEKKVHYSIRKFSIGVASVAVASLFMGSVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAKKKVEEAKKKAKAQKEEDYRNY
                     PTITYVKVKEAELELVKEEAKESQNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEE
                     EAKRKAAEEDKVKEKPAEQPQPAPAP"
BASE COUNT        20065 a        10983 c        12703 g        20581 t
ORIGIN      
        1 aagattttta agttttttta aacttttttt catcaagtgg tcctgacgca acataccata
       61 gtccgtacgg gattcgaacc cgtgttaccg ccgtgaaaag gcggtgtctt aaccccttga
      121 ccaacggacc tgagttgtta ttttcaactc ttactattat acagtctttt caaactttgt
      181 caactacttt ttctaatttt tttcattttt tttgcatgac ttactagtgg gtacggatag
      241 taaactcctt aaacacaatg cgtaagtctc ttaatactct ttgacgccct cgaaatcgtt
      301 cattgcttaa gacgcgttct agttcttctt gtttctcttt actttgtttg tttctataat
      361 ctcttagtgt ttcatgaaag agataataat catctagcca gagacctccc tcacttatac
      421 gatgactgag ctcacccact tcttcatagg gttctttatc gtatctacgc ttctgacttt
      481 cctgcttacg gatatagtct aaaattcgat ttcgaaactt ggttttgaaa tatttcctta
      541 aacgtggaat atcgtctgcc agtccttctt ctctactaat caattcatgt aagcagagca
      601 tgccttcttg gtcccaatcc gacaattccc ataaatgaag gtaatattca tttctacact
      661 tatacacagt cccttggact tcttcataca attctttaat cataattttc ccctttctag
      721 atacagtcta acagattaga aaacacattt gttccatttt atccattctg ttccctttag
      781 ctcctaaact gcacaaaaaa gagaggctcc agcctctctc agggttattt ttcgtcattc
      841 atttttgact ttacttcatc ataggatagt gcatgagatt cctcttctac tgcttcaggc
      901 atctttcctg tttcgtaaag agctttaatt tgtgtactat ccaatgtttc gtatttcaat
      961 aatgcttctg caattaactt gtgagtttca cgatttgact gaataatttc agcagcttta
     1021 tttcgtgcct catttaataa tgaacgaacc tcttcatcaa tttcataagc tgtttgttct
     1081 gaaattgatt tttgaggact ctgtgcacca aacatagcat ggtttccttc atattgtact
     1141 gggccaagtt tttcactcat accgtactct gtaaccattg cacgcgccat ttgtgtcgct
     1201 tgttcaaagt cgtttgaagc tcctgtagtt tggacattaa agataatttc ttcagctaca
     1261 cgtccaccca ttaagccagc caattgctct ttcatatctt ctttagatag aagcatttga
     1321 tcctctttag gaagtgcaat catgtatccg cctgcacggc cgcgtggtac aattgtaacc
     1381 ttatggacaa cgcgagcatt cgacaagact agaccaacaa tggtatgtcc tgcctcatgg
     1441 taagcaacca attctcgttc tttttgtgaa actgtcttat ctttcttaga aggtccagca
     1501 ataactctat cttctgcttc atcaatatct gaagcatcaa ttatcgattt attgcgacga
     1561 gcagcaacta aagctgcttc attcaagaca ttctctaaat cagcaccaac aaagcctgga
     1621 gtttgttgag ccactaattt caaatcaaca tcttctgcta aaggcttgtt cttagcgtga
     1681 actttcaaga ttgcttcacg acctttaaca tcaggacggc caaccaatac ttttctatca
     1741 aaacgtcctg gacgcaaaag ggcaggatca agtacatctg aacggtttgt cgcagcgatg
     1801 acgataatcc cttcatttcc ctcaaaacca tccatctcaa tcaaaagttg gttcaaggtt
     1861 tgttcacgtt cgtcattacc tccgccgaga ccgactccac gttgacgtcc aacagcatca
     1921 atttcatcga taaagatgat agctggtgct gcttttttgg catcctcaaa aagagagcga
     1981 acacgactag ctccaactcc gacaaacatt tctacaaagt cagaacctga gatactaaag
     2041 aatggaacac ctgcttctcc agcgactgcc ttagcaagca aagttttacc tgtccccgga
     2101 ggtccctcca aaagaacacc tgctggaata cgggctccaa gttttgtgaa tcgttttgga
     2161 tcttttaaga actcaacaac ttcaactagt tcttgttttt cttcctcagc tccagcaaca
     2221 tctgaaaatc ttactttaat atcttcttta tttgctgctt tagccttact acgtccaaaa
     2281 ctcattggat tacggccatt gcctcctccc atatttccca tcatagagaa taggaagaag
     2341 aatagaattc caaatggcac aatggatacg agtagattaa tccatatacc acttgaactt
     2401 tcatgcttaa cagttacttc tgctttatgg tcagtagcaa gtttttgcaa ttctgatacg
     2461 gtagtatctg caggaagaat agtgctggta aatttctcta ccttagtaac agatggcgtg
     2521 aaaaactgaa tacctgttcc ttctttactt gttttaggat ttttatagac accagaaact
     2581 tcgataacac taccatttgg ttggtaagtt aattctttta cattaccatc ggtaatttct
     2641 tgtaccaact cagtatagtt gatttgctga cttcctcctg agttattccc agaatagaaa
     2701 tactggaatc ctgtcacaag gaaaaagata aataataacc atagaaaagg atttttaatt
     2761 aaaccattat tttgtttttt cattaaagat tattctttct aatttgaata cacttcctct
     2821 ttcaatactc caatataagg aagattacga taattttctt tgtagtctaa accataacct
     2881 actacaaact catttgggat agtaaagcag gtatagtctg cctcaatttc tacaacacgt
     2941 ccttctggtt tatccaacaa ggttgcaatt ttaacagaag ctgcttctct ttctttaaac
     3001 atatctcgca aattcttcaa agtttgacct gtatcaatga tatcttctac aaatagaaca
     3061 tgtcttcctt tgatatcttg agtcacatct tgtttaatat tgataacacc actacttgct
     3121 gttccaccat ggtagctaga aaccatcatg aagtccattt caatatgtgt atcaatatgt
     3181 ttgaccaatt cagccataaa aggaatagat ccttttaaaa tcccaactaa gattggattt
     3241 tttcctgcat agtctttagt taattgagca cctagttttt tagctgcttc tgtaatttca
     3301 tcgtgtgaaa cgaggacttt tttaatatcg ttttctaaca ttttttacct atctattttt
     3361 tctatataaa gtacagtgtt cattatatca tttttcgttt ttttactcaa attattggtc
     3421 gcaattccca aaattgagac aatttcacca aattgctcaa taataagagc agagtttctc
     3481 ttttccatag ggattttcaa atcaataaat aaacgtctga gtttttttct atgcccattt
     3541 tgaatcaaaa catctcctgt ttttcgatga cgaatgtgta tggatgtttc acgtgaaaca
     3601 ggtatttgtt gaattaattc accttctaat ggaagtccaa aggaaaataa atatccttga
     3661 taagctacct gattttgata gtgtaacaca agttcatctt ccttttcatc agcctgcgga
     3721 ctgattttac aaatctgaaa ctgttggtac tcttttatca attcatagcc atttttaatc
     3781 ggatgacgat actggctttt agattttaaa atctgctgaa cttcagcaaa ctgagctttt
     3841 gtaagattca aatctggaaa acgattcaga taagtttgaa gtaaaactct ttgtgtagac
     3901 tcagagtaag aaaataactg ctgtaaatct tccacattaa tattgttaga taattcagct
     3961 attgccaaat cataatctaa aatttcattg ccaatgccta agattgcatc cctaaatcga
     4021 ggattttctt tttccaattc tggtaagtaa gagtttcgaa tacgatttcg aaaataatga
     4081 ttctcctgat ttgatgtatc ttcaaagtga aaaattgatg gaaagtcttt tttctgaaaa
     4141 tgcaagaagg gacgaatgat ttctatctct ccgactactt gcttctcctt aattcctgat
     4201 agatagcgca agcgagttcc tcgaatcaag cgcatcaaaa tcgtttccac ctgatcatca
     4261 gcatggtggg cagtgactaa agctgtcgca cctgtctttt tcataacctc ttgaaaaaaa
     4321 tcataacgaa aatttcgtgc acgcgcttct gaaaattctc ctgaaaaatt gctgatataa
     4381 ataggaagct ctgcttcagc agccaacttc cttaattcct tttcttccca atctgattca
     4441 attctctgct tatgattcac atgagccaga atcaattcaa tctctaactc tttttgataa
     4501 gtagacaata ccttaaatag aaacatagaa tctaatccac cagaaagagc tagaaccgcc
     4561 ttagcatgct ttttgaaata tcccttcttg agaaaatgat ttaaaaaatc tggttccctc
     4621 attttagaac ctcataaaca tccttggcta tcttagaaat cgtatcataa tcagaattct
     4681 tagtgaaaat agaaagaata aatggagaat ctgcatagac aacacccgta tcatgcttaa
     4741 attcatccgc atctccaatt ttatgagcta ctttaacaga aacacctttg gcaattcgct
     4801 gactatcaaa atctgtttta gtcaaagact ctagcacaaa tccattttga ttataaatag
     4861 cttccataaa cttcccggcc atcttagaag aaatcaattt ttcttttgga tcccaatcat
     4921 ctcccataat ggcagacatc ttggatttga atgtggcatc agattggttt gaaatgtaat
     4981 atcccaatag attatgagct acattatcag attcttttga tactttcgta attaaatcct
     5041 ttaaagaata ttctttatta tcttcttttt taggaagact accacttccc tctggtttat
     5101 aagaacctgg aaaatcattg actgcagata cgtattttac agtcgtatct aactgataaa
     5161 gaccctcatt tattttttct tgcgtataat agagataaga gagtttcaaa acgctggctg
     5221 catacatctt ttcatcttga ttgataccag cttcttttcc agtagtcagt tgcttaacat
     5281 aaatagagaa agaatctttc tgatattttt cagataacat ttcttgaact ttactcatcc
     5341 gattatcttc ttcagaagtt gattctttag ctacccatcc agcctgatca atatgtagaa
     5401 attctcttcc ttctacaaac atggtcttgt cgattgatac ttgcgaataa gctgataagg
     5461 atgatttcac ttcttttaaa tcataaggac tattgtacag tttaaagtca gattctaacc
     5521 atactttttt tattgttgga gttacctctg attgatcata taaaaatcgt ttgtccgcag
     5581 ctataaattg atgatttgat agcttaaata ctggaattcc ttgtttattt aagcgccact
     5641 cggttatttg aaaacttgtt ttgggagtca atttcccaga ttccactact aaatcttcat
     5701 tcgcataaac aggaacctct ccataaacca tgggagaact taatttttct ctaaaataaa
     5761 taccaaagtc agattgtgaa aggtaataaa tttctttcga agtatagact acttcttttt
     5821 ctgtgctaac gacttttgaa atggtcaaaa aacttggtag caacaaaata attaagaatt
     5881 tacgcattct tcctttcctt ttcttcttgt aaacgcaata attgattttt atcagccaat
     5941 tcttccagct tttcatctga caaactcaaa aattgctcta ttacgtctaa taaattttcc
     6001 attttatcac ctttgaagca agtcaggaat cgtataaact ttttccctcg acttagaata
     6061 atagtacttc gctcgtgtat atttagcagc ataatcttca tctttcaact tggtagcaaa
     6121 tgctgtctcc ttatcctttt catcactcaa agtttgatac tgagtttgca agtctgctaa
     6181 ttgctgacgt ctttggagta attgctgata actctgcgct aaattaaaag ttggcaagat
     6241 aaataatagc ataatcaaaa tcaatacccc tcccataaaa cgattccgtt tttgtcgttc
     6301 tttcatcagg tagcgacgac gttggtattc attttgaata aaagaattat tcaattgtac
     6361 aatattttta gacattttct tctacccgtg tttcactgat aatttcatac attcctgctg
     6421 catcttcttt ttttgtacta tctttcatct ctagtacttt tacaagcagc aacttattgc
     6481 caaagcgaat ttcaacttgg tcattaactt tcaagtccgt tgaacttttg gccaagattc
     6541 cattaacctt gattctacct ttatctgcta cttcctttgc gactgtacga cgcttgataa
     6601 ttcgcgatac ttttaaatat ttatctaatc tcatccttat tacctcaatt tattattgta
     6661 ccatttttat ctattttata gaagaaaaat atcaaatgga attttcttcc ttagactctt
     6721 ttatctctaa taaactttct ccaaaaatca gcaaaccttc taaaatttca taatctttct
     6781 tattttggac atcaaataca agctccatta atcccttatt ctcagcgatg cctgctttta
     6841 agttcgttac ggataaagct ttaaaataat cttgagctaa aaacagtcgt tgagtgactt
     6901 tttcaaattg aattgtaatt ttattatctt ttctttccac acgttgaaca aagaccttgt
     6961 ccaagtatga tttaaccaaa ccaatctcta aaagataggc tactacatct gggtattctc
     7021 caaaacggtc tatcaactcc tcttgtaact cttcataatt gacacggttg tcaatttgac
     7081 gaattttctt gtaaatttca atcttatgtc gttgatcaga aatataagta tcaggaagat
     7141 aggcatcaat ttgcaaaatc aactcagcat tccctttggt tcttgtgtta gcgttagcat
     7201 taccgtttcg tttagcaata gcttcctcta ataactgcga atacaattca aaaccaacag
     7261 aatcaatgaa accagactgg gattttccta aaagatttcc tgctccacga atcgaaagat
     7321 ctcgcattgc aatcttaaag ccagagccca attctgtaaa tcctttaatc gcttctaatc
     7381 tcttttcaga gacttcactg attgattttt ctggacgata catgagataa gcataagcaa
     7441 tacgattact acgaccgact cttcctctta actgatataa ggttgacaag cccatatggt
     7501 ccgcattttc aataaataaa gtattagcat ttggaatgtc cacccctgtc tcaataatag
     7561 tagtcgtcac caagatatcg tattgtccct caataaagtc taatagagta ttttccaact
     7621 ggacttcact cattcgacca tgaacatatc caatcgaagc ctccggaatc aactcctgta
     7681 attctgaaac cttctgaaca attgtatcaa ctttgttgta aagatagtaa acttgacctc
     7741 cacgctccat ttcacgcaag acagcatcac gaatgacact atcattcttt tccaaaacat
     7801 aggtctgaac aggatagcga ttagtcggcg gagtttcaat aacagacaaa tctctgattc
     7861 ccagcataga catatggagg gtacgaggga ttggcgtagc ggtcaaggtt aggacatcca
     7921 cttgtttctt cagttctttc aaagtttcct tatgcttgac accaaatcgc tgttcctcat
     7981 caataatcat caagcccaaa tcagcaaaca caacatcttt tgacaaaaca cgatgtgttc
     8041 caatcaaaat atcgacttga ccgtttttca atttttcaag tgttgcagtc tgctcttttt
     8101 tacttctaaa gcgactcaac acatcaacat taactgcaaa attttggaat cgttccttaa
     8161 aattcgtata gtgctgttgc gctaaaaccg tcgtcggaac tagaatgaca acctgtttgt
     8221 gatcattgac tgctttaaag gctgcacgca tagcaacttc agtctttcca aaaccaacat
     8281 ccccaactaa aagtcgatcc attggctgag aagcctgcat atccctcttg atttcctcaa
     8341 tactacgaag ttgatcatcc gtttcaacat aagggaaagc atcatcaaag gcatcttgat
     8401 catcatcatc agctgagaaa gcaaaaccct tcaactgact acgttcagag tagagtttga
     8461 ttaaatcatc agctatatcc tctacctggt tcttaacctt ttgcttggcc tttttaaaat
     8521 gaccgtcatt taatttattg agttttggag ctttaccatc acttgaaata tatttggaca
     8581 gtagatgaat ctgttccacg gggatagaaa tttgatcacc attttggtat tggacactga
     8641 cataatcgcg atgaattccc ttgatttcaa tggtttcaat tcctagatat tgaccaatcc
     8701 catggatatg atggacaaca tagtcccctt tttcaagttc attgtaatct tttaatctct
     8761 ctgcatttga aacatgttgt cttcgaaaac gacgctttaa tttcttttga aaaatctcat
     8821 gttcagttat caataaaatc ttttcatcta caaaatgaaa accatgtctg agattaccct
     8881 ctattaagtt tacagattct ttacagatac ttgtcttatc tctagaatcc aatttaatct
     8941 gatattcctc taacatatcc tccaatgttt tacttcccat tgaattgcta gactgcagaa
     9001 taatggtgta atccattttt ttatatcgtt caatttcttc ttttagaaaa gaaaactgat
     9061 tgaaaaattc ctgcatagga tattgattga attgataaat tttgtcaaat ttgagatttc
     9121 ctaaaccctt ttgaagatta gagaaaaagg tcactggact ttgtttttta tagatttgtt
     9181 caatatcaga aaaatactgc atatcagaaa atgctttact attctgtaat tcttctgtaa
     9241 agtactgcgc taagtctctt tcaaagactt catactgatt catcaatttt tgataatcat
     9301 caaagaatat tggagtatct ttttcaatat aatcaaagac agtccatgtc ttatcatagc
     9361 acaaagataa aaacttccga gagtctgcat gactttgttt ttggtgaaaa cttgaaagaa
     9421 tttcttctag gtatgatttc aaaataggtg ataaagtttt tgaaatttgt ttttctaaag
     9481 ctgactgtcc tcgttgataa tccttttctc tcaaaagcat atcactagct ggaaagatag
     9541 tgagttctgt cttattttct ttcgataatt gtgtttctac ttcaaatgac ctgataccat
     9601 caatttcatc accaaaaaac tcaattcgac aaggttctaa ctgggatatt tcaaaaatat
     9661 ctaaaatatc tcctcgaaga ctaaattcgc cctgagtttg tactttagta acttttcgat
     9721 agccattttc ctttaactga tggataaacg cgtgttgatc atattcttca ccaactgaga
     9781 tttttacaat actatctttg aatgcattgg gagacggtaa aatcaatcga cttgctgcga
     9841 tattacaaac taaaatccct ttcttagatg aatcagtcaa aaaacgcaag gcttcaaccc
     9901 gtgaaataat tttttcctgt gaagacatca aaaactccac cataggagca tcatctacca
     9961 aaaatggata gacgagttcc tcacccaaga tagatataag atcactaaca agtccttctg
    10021 cttctccata agttgacgtc aataacacaa tcctatcttc tttttctaaa ctgcttgcaa
    10081 ttgcaagcgc cttagtagat gttgataaac caagtattag ttgtcttttc ttatctgtta
    10141 aattttgatg ccatttttta atctgatcat tttctgagaa taaatctaat aaggtcacca
    10201 tttatccgtt atacctctgc attgttttct caaaattttt ctcttgtaaa tagtagttta
    10261 cagaatcgtc aactttgtca acagactgta aaataccgat ataatcatcc ctgtcaaact
    10321 tactcaaaac atgatgaaca actgacatac catttttagg tcttccaatt ccaatcttaa
    10381 cacggttaaa gacctgagtt cctatatgtt gaataataga cttgatacca ttatgaccac
    10441 ctgctgagcc ttttgctctt aaacgaattt tcccaacttc catgtcaaga tcatcgtaaa
    10501 tgataagtaa atcgtcaata tccaaaccat agtaagttaa taaagcatga actgcttttc
    10561 cactttcatt cataaaggtc gttggtttaa ccagataaat tttttctcca tttaggaaaa
    10621 aggatgctag gtcagcttga aatatcttat cgtgtgtaaa agtgacattc tgtttcttcg
    10681 ctagttgatc aatcaacata aaaccaacat tgtgttttgt ttcaaaatat ttatcccctg
    10741 gatttcccaa gcctacaagt aatttggtca tttatttttc ctttcaaaag ccaaaagggt
    10801 tggaattttt ttccaaccta attgacacca tttattaatt tttagacatt aaagcggaat
    10861 tccatgatat cgccatcttg aacgatatat tcttttcctt cttcacgcaa gcgtccagct
    10921 tcttttacgg ccttttcaga tccgtatttc actagatctt catatgacat ggttactgca
    10981 cgaataaagc ctttttcaaa gtctgagtgg ataataccag ctgcttgagg agccttcata
    11041 ccacgtttga aagtccaagc gcgaacttct ttttcaccag ctgtgaagta agttcccaat
    11101 ccaagcaagt ggtaagctgc acgcgtcaac ttatctacac ctgattctgt caaaccaatg
    11161 gcttcaagaa actctttttt atcttcatca tccaattcag aaatttcttc ctcagcacgc
    11221 gcagaaataa cgactacttc agcattttct gtcgctgcaa attcacgaat ttgtttgaca
    11281 tagtcgatag agtcaggttc tgaaaccaca tcctcgtcca cattagctac ataaagaact
    11341 ggtttagtcg tcaaaaggaa aagacctttg acaacctttt gttcctcatc tgtaaattca
    11401 atggtacgag ctgatttccc gtcttctagg actggtttaa tcttttgaag aacattgaat
    11461 tctgctactg attctttatc tttttgcgta cgtgccatct tttctacacg cgcatatcgt
    11521 ttgttcactg attctaagtc agcaagaatt aattccagat taattgtatc aatatctgca
    11581 agtggatcta caaaggcgtc ttcacgtcct tgctcgcgca ttacattttc atcatcaaaa
    11641 gcacgaacta cgtgaacaat cgcatctact tcacgaatat tggccaagaa tttattccct
    11701 agcccttctc cttttgaagc tccttttaca atccctgcaa tatctgtaaa ttcaaatgtt
    11761 gtgggaactg tctttttagg agttatcatt tcagttagtt tttgtaggcg ttcatctgga
    11821 acttccacca ttccaacatt tggatcaata gtcgcaaatg ggtagtttgc tgcctctgct
    11881 cctgcttttg taattgcatt aaatagtgtt gatttaccaa cgtttggcaa accaacgata
    11941 cctgctgtca aagccatatt tctcattctc cgttttcatt tcaatcccta atattataac
    12001 acaaaaaggg ataaagtgct aaccctctaa ctaagggttc tcagtcaata attttattca
    12061 tttttcgctc aaaatcatat cgccccatca tgacaacatg ctcacaatta ctgcatttta
    12121 ttttgatatc tgctcctaca cgtgtaattt cccaacgatt agccttttta ccagtcgact
    12181 tgattgtaca agcgtgtgat tttttcatct caacaaaatt tccaacttga tacatactac
    12241 tctccttttc tttttcgatt atatcataaa agaggcgagc caggctcaac ctctttcact
    12301 taatttgtac gaactggtgt aatgagctgc atgaagtctt cgtcagtatc tgctggcaca
    12361 agagtaaatg gacgaacagc tgagataaag ctaatggtca ccttttcgct atttaaagct
    12421 ttaagagaat caatcaagta agttgggttg aaactaatgg tcaaatcttc accagtaacc
    12481 tgatcagtat cgatttcttc gtttacttta ccaacttctg gagagtgaac atgggcgcta
    12541 acaaccccat ccttaatttc aagtttcaca gtaccatttt gagtcgcact tgataaaaga
    12601 cgggcacgct ccattgactg gcgtaagttt accacattaa aagtaatagt agtgttaaag
    12661 tctgttggaa tcaagcgatc tgtatcagga tagtttcctt ctaggagacg agtatagaag
    12721 ctaatatttt cgcttctaaa gaggatttgg ttattggcaa agaaaatctc tacagcttcg
    12781 atatcatctg taaataccgc tgaaaattcg cgtagagaac ggctaggaat tacgacatca
    12841 aaatcatcac tatttttttc aagagtcaat tttttctggc ttaggcgatg agagtctgtt
    12901 gcaactgttt ttaactcttt gtgttgactc aatacgaagt ggacacctgt taaaatcgga
    12961 cgactctctt gtgtacttgc agcaaaggct gtttcattaa taattttctt gagtaatttt
    13021 gtttcaagta ttaaaggagt gcttgctgaa atttcttgga ttcgtggata ttgttcgcta
    13081 tcttttcctt ttagggtaat ttctgatttg ccactggtta aaacaatttg attttgttca
    13141 atttctttaa aatcaagagt tacatcaggt aaactagata ctacattgat aaagaaagaa
    13201 gcttcaagaa ggatcgaacc taaagaagta attaacaaac cagcatcttc atttttttga
    13261 gaaataaaat tttcaattga aatttgacca tttgaaccaa ttaaagtaat accttcattg
    13321 gtcacgtcaa tttttactgt tgataaaata ggaatggcat ttttagaact aatagctctc
    13381 ttagtagtat ttaatgcttg tagaaataaa tttttattaa ttgaaaaatg aatcatggat
    13441 tctcctttat ttatttttag tattagaaag ataatagtaa taatagagtc tgtgaaatct
    13501 gtggaaaaca gcctttaaac aagtcatatc aagtttttta gcttgtttaa aaaatgtgga
    13561 taaaaaagat aaaaaactaa aagttatcca caaattattt gattttcttt ttgattgatt
    13621 caatttctaa acgtaaatta tcgtcttgat caatcaaaga ttttattttg gcatgggcat
    13681 gaatgactgt ggtatgatct tttcccccaa attccttccc aatttttgga agactattat
    13741 ctgttagttc tctagataaa tacatggcta cttgacgggc caaaacaata ttttgaaggc
    13801 gtctacttcc cttcatttct ttgatactaa caccataaaa gttaccaact tcagtttgga
    13861 ttttatcaat tgggatgacg agcatttggc taacatcttg tttgcgggct ctaatggctt
    13921 ctgcagcaat atcaatagtg atatccttga ttttttttac tctggcaatt aaagtgatgt
    13981 cgttgatggc tccctcaaga tctcgaacat ttgaatcaaa ttgcccagct aggtattcta
    14041 gagtatcact ttggaaattg tagcctaaat gttccgtctt actttgtaaa atggcaatac
    14101 gtgtttcaaa gtcagggggt gtgatagttt gtgtcaatcc ccaactaaaa cgcgtgacaa
    14161 gcctctcctc gagcccttct agatgttttg gactacgatc actcgttagg acaatctgtt
    14221 tttgcttgtc atgaagggcg ttaaaggtat tgaaaaattc ttcctgagtt gcgacttttt
    14281 ttccgctgag tgactgtata tcatcgatta acaaaagatc aagactacga taggtctttt
    14341 taaacttttc catttcccca agtcttaggt gatcaagaaa gtcattaata aagctttcgg
    14401 cagggatata tttaacacgc gcattaggaa tattttttag aatttcattt ccaatagcgt
    14461 ttaataagtg agtcttacca aggcctggtc ctccatagat aaaaagaggg ttataggtca
    14521 gagccaaatc ttcagagaca gctaaagcgg ctgatacagc ccaaacattt ccatcccctt
    14581 gaataaagtt atcaaaggta tacttttctt ttaatcccgt atctgaataa ggaatagata
    14641 ctaactttgg actatagtca taaagagtta aatttgtagc ttcttcaact tgtgagctag
    14701 tcgtatcttg aggtttggtg aaaatatagt ggggagttat ttcagcgtca taaatttcaa
    14761 aaccagctac tacaataata tcttttagtt gtttttccca gaccatttcc atttcagagc
    14821 gaggtagaaa tatagtggca acattttcct ctaccttgat gagttcagct tgaatagcat
    14881 agaaatcata catggatcga gtcagtcttt cttgtgcaaa ttctaatata cgattccaaa
    14941 attgtttttc tttcaatcct ttctcctcct ttactattta aaagtttaat actagagata
    15001 ttttaccata gatagcaaga attttccaca agctgtgaaa aataatccac aatgttacca
    15061 aactttatcc acaggttggg gataaaagaa gaaattattg atttattaag ctttttatcg
    15121 aaaaacatag tggataacct tgtgagataa aaaaataaaa gaacagcctt atttcaggct
    15181 gttgataatt ctactatatt cttcttgatt tgaaaaagaa ataatgattt ttccactgtc
    15241 ttttttagat agtttaattt ctacatctaa tccgagtagt tttcttaact gtttttcttc
    15301 attttgtatg aaatgattag ttttttgctg tttcttttgt tttttctctg tcagaagagt
    15361 ttctaacttc cttacagaaa tatcttcttc tataatccgt tgaaagaaat agtcttgttg
    15421 ttccttattt aacccaacta gggaacgcgc atgggcttgt gatagtttgc cattttctac
    15481 ttctgagaga atctgttctg gcaaggaaag taaacgaatg gagttgctga tatatggacg
    15541 agacttgccc atcttatctg caatttcagc atgggtgaat cctttctcta cgagagattc
    15601 ataggcgcgt gcttcttcta ttgggtttaa attttctctc tgtaaatttt caataatgga
    15661 ctggaccatc atctcttggt ctgaaatctg tttaacaaca gctgggatag accgtagacc
    15721 agctaaaagt gaagcccgat agcgtctctc tcctgcaagg atttcataac caataacagg
    15781 agattgacga acaataatcg gttgaatgac cccattttct ttgatagact gtgctagttc
    15841 atctagcttt tctctatcaa attcttttcg gggttgatag ggattttttt gtatatctgt
    15901 gatagaaatc atttcaaatt tttccatgat tctacactaa cacatctttt ctcttatgta
    15961 aagctttctt tacatagatg tcaattaaga ttctaaatca cctgaactct tgttaagttt
    16021 gatagaggta gtttcttctt tcccgttacg atagtaggtt atcttaatgg tgtctccgat
    16081 agaatggttg taaagagcac tttgtaagtc tgttgatgaa gcaatctctt tgtcatctac
    16141 ttttgtaatt acatcgtatt tttcaaggtg accattggca ggcatattac tttgtaccga
    16201 acgaacaatt acaccagatg taacattact tggaatattg agtcttctga tgtcgcttgt
    16261 actcacatta gataaattaa ccatctggat tcccaaagct ggacgcgtca cttttccgtt
    16321 tttttctaac tgttcaataa tattgatagc atcatttgca ggaattgcga aaccaagacc
    16381 ttctacagat gttcctccat ttgtagcaat tttacttgag gtaattccga taacctgccc
    16441 ttgaatattg atcagtgggc cgccagagtt acctgggtta atagcagtat cagtttggat
    16501 ggcttttgta gaaatagctt gtccatcttc cgattttaag gatacatttc tattgagact
    16561 ggatacgata ccttgagtga cagtatttgc atattcagaa cctaacgggc taccgatggc
    16621 aatagcagtt tctcctacag ttaacttact agaatcacca aactcagcta ctgttgtcac
    16681 tttttctgaa gagattttga cgacagcaat atcagagaaa gtgtcagctc cgacaatttc
    16741 tccaggtact ttagtcccat ctgacaatcg aatatctact ttgctggcgc catttataac
    16801 gtgattgttg gtgacgatgt aagcttcttt atcattcttt ttataaataa ctccagatcc
    16861 ttcactagag attcgctgag aatctgtgtc agtatcatca ttgccaaata cgctattttg
    16921 tctgtttgcc gaataagtaa taacagaaac aacagcatct tttactttgt taacggcctg
    16981 tgttgttgaa ttttcgttct tataggcagt ttgtgtaata gtactattgt tgttagagtt
    17041 gtttacacta cttttttgag ttagttgagt tattgaaaaa ctacccaagg ctccactaaa
    17101 aaagctaatg acgataacga ctaataattg aaaccatttt ttgtaaaatg tttttagatg
    17161 tttcatattt gcctccatat gtttgaatta ctgaaagtat aaactgacta gcttaattat
    17221 aacttaaaca caaaagtttt acacaaactg tggataactc ttttgaaact gtgattttct
    17281 taattgaaat ctatttttta ttttgtgaat aagatgtgaa aaaatagaga atatgttaga
    17341 atagagtcat gaaaattaaa gttgtaacag ttgggaaact gaaagaaaag tatttaaaag
    17401 atggtatcgc agagtattca aaacgaattt ctagatttgc taagtttgaa atgattgagt
    17461 tatcagatga aaaaacacca gataaggcca gtgaatcaga aaatcaaaag attttagaaa
    17521 tagaaggtca gagaatttta tcaaaaattg ctgaccgtga tttcgttatt gtgttagcca
    17581 ttgaagggaa aactttcttc tcagaagaat ttagtaagca gttagaagaa acttctataa
    17641 aaggattttc tactcttact tttattattg ggggaagttt aggattgtca tcatctgtaa
    17701 aaaatagagc caatctttct gtcagttttg gtcgcctaac cttgcctcat cagttaatga
    17761 gactagttct tgttgaacaa atctatcgcg cttttacgat tcagcaggga ttcccctacc
    17821 ataaatagag aattgacttt taattgaatt tttggtagaa taattgtgtt aggtctcata
    17881 gctcagctgg atagagcatt cgccttctaa gcgaacggtc gcaggttcga atcctgctgg
    17941 gatcaatata atagcaaagc tgggaatttt cccggctttt ttcttaaaaa agtacacttt
    18001 gggagaaaaa aatgacagtt gagagaattt tatctaaaac gaaattccat tttgtataat
    18061 ggtttttgta agttagctta caagaaaaaa acattttagg agattttatt atgaaaaaca
    18121 cagttaaatt ggaacagttt gtagctttga aggaaaaaga cttacaaaag attaaaggtg
    18181 gggagatgag gctgtcaaaa ttcttccgtg attttatttt acaaagaaaa aagtaatgaa
    18241 ataaggggaa agagtaatgg atttatttgg atttgggaca gttattgttc attttttaat
    18301 tattagtcac agctaccatt taatttgtaa aggtcaaata aatagaaaag aattattcgt
    18361 ttttggtgct tatacattac taacagaaat agtatttgat tttcccttat atattctata
    18421 tttagatggg ttagggattg caacattttt atttcctttg ggcctatatt cctattttcg
    18481 atggataaaa cagtatgaga gggatagagg actattccta agtttactac tatctctttt
    18541 atatgagagc actcataact ttctgtccgt aactttctcc tctataacag gagataattt
    18601 tgttttacaa tatcatttcc cattcttttt cgttgtgacg gtgttgacct attttgttac
    18661 attaaaaatc atttattatt tccatttgga actagcctat tttgacaagg actaccttta
    18721 tcctttcttg aaaaaagtat tttttgcttt actattgcta catattgtat ctttcgtttc
    18781 agatatggta agtacgatta aacatttgaa tagttttgga agtattttgt catctattgt
    18841 ctttatctct ctccttttga ccttctttgc aatgaattct cataaagttc aaatggagaa
    18901 agagattgct ttgaagcaga agaaatttga acagaaacat ttacagaatt acacagatga
    18961 aattgttggt ctgtataatg aaatccgtgg ttttcgacat gattatgctg gaatgcttgt
    19021 cagcatgcag atggcaattg acagtggtaa tttacaggaa attgacagaa tttacaatga
    19081 agttttagtc aaagcaaatc ataaattgcg ttcagataag tacacttact ttgatttgaa
    19141 caacatagaa gactcagctt tacgaagttt ggttgctcag tcaattgtct atgctcgaaa
    19201 taatggtgta gagtttacac tggaagtaaa agatacgatt accaagcttc caattgaact
    19261 attggatttg gttcgtatca tgagcgtttt attgaataat gctgtcgaag gatcggctga
    19321 tagctataaa aagcagatgg aagtagcagt tattaagatg gaaactgaaa cagttattgt
    19381 gattcagaat tcatgtaaaa tgacgatgac tccttcagga gatctatttg ccttaggatt
    19441 ctccactaag ggaagaaatc gcggagtcgg attaaataat gtgaaagaac tactagataa
    19501 gtacaacaat attattttag aaacagagat ggaaggcagt acatttagac aaatcattag
    19561 atttaagagg gaatttgaat gaaagtttta attttagaag atgttattga acatcaagtg
    19621 agactagaga gaatattgga tgaaatttcg aaagaatcga atattccaat atcatacaag
    19681 acaacgggaa aagtccgtga atttgaagaa tacattgaaa atgatgaagt aaatcaactt
    19741 tatttcctag atatcgatat tcatggaatt gagaaaaagg gatttgaagt ggctcagctc
    19801 attcgtcatt acaatcctta cgctattatc gtctttatca ctagtcgatc agagtttgcg
    19861 actctaacct ataaatacca ggtatcagcc ctagattttg ttgataagga tatcaatgat
    19921 gagatgttta agaagagaat tgagcaaaat atcttctaca cgaagagtat gttacttgaa
    19981 aatgaagatg ttgtagatta tttcgactac aattacaagg gaaatgattt aaaaattcct
    20041 taccatgata ttttgtatat tgaaacaaca ggggtctctc ataaattgcg cattattggt
    20101 aagaattttg caaaagagtt ttatggtacc atgacagata ttcaggaaaa ggacaaacat
    20161 actcagcgat tttattctcc tcacaagtca tttttggtaa atataggcaa tatcagagaa
    20221 attgatcgaa aaaacttaga aattgttttc tatgaagacc atcgttgtcc tatttcaaga
    20281 ttaaaaatta gaaaattaaa agatatttta gagaaaaaat ctcaaaagtg attgacaatt
    20341 agcaagaaat tgatataatg gttatatctg ctacagatag aaggtccgtt ggtcaagggg
    20401 ttaagacacc gccttttcac ggcggtaaca cgggttcgaa tcccgtacgg actattttat
    20461 ccgccatagc tcagttggta gtagcgcatg actgttaatc atgatgtcgt aggttcgagt
    20521 cctactggcg gagtatagat aaaagggaac acagctgtgt tcctcttttt gtatcaattt
    20581 gtatcaccaa gcattttcat aaggaagtct gttatttctt gagaactttc tttttttcca
    20641 tgtgcaatcc aagtttggca gacaccaaaa agtgcatgag ttagatagat gctactatat
    20701 tctaattcag tggtatttag attcagttgc ataaatcgct tttgtaaatc tgtactgagc
    20761 atgatatgaa gtttatttcg taagaaattt tggatttctt tagtcccatt ttcagaaaga
    20821 agggcagcca gaagtggttc tgactctaga tattcaaaaa cttctaaaat agcgtctctt
    20881 ttgtgatgag catgtttttg aaaaatatat tcaaatgtat ggaatagctt gctttgatag
    20941 tgctcaatca tatcatactt atccttatag tgagtataga agctggaacg actaattccg
    21001 gctttttcta ctaatttgac agtagaaatt ttatcaaatg gctgttccat cagtaattgt
    21061 accatagcgt tttcaatagt tcgctttgtt tttaagcgtt tgttactttc ttgcatattt
    21121 cctccttgta aacaaattag actatatgtc taaaaataga ttttttatct tgtaatttag
    21181 attttttaat gtataatcta ttatatcaaa attttagaca atatgtttaa aaaaggagaa
    21241 actatgttta aagaatggaa agcaatttaa aaaaaaacaa cctttattat tgtcatgatc
    21301 gggatttctc ttattccagc tctgtacaat atcatatttt tgtcatcaat gtgggagcca
    21361 tatgggcaat tgtctgactt acctgtggca gttgtaaata atgataaaga ggcttcctat
    21421 aatggtaata ctatggcaat aggaaaagac atggtgtcca atttaaaaga aaataaaacc
    21481 ttggattttc attttgtaga tgaagaggaa ggaaagaagg gattggaaga tggcgattac
    21541 tatatggtag tgactttacc aagtgattta tctgaaaaaa caactacatt atccaatatt
    21601 caatcgacag cagcttatca atcattgaca agtgagcaac aaactgagat aagtgattct
    21661 gtatctcaaa attcaactga tagtattcaa tcggctcaat caattgtagc tttagtacaa
    21721 gatttacagg gaagtttaga aaacttacaa aatcaatctt ctaatctttc gactttaaaa
    21781 aatcaatcta atcaagtatc acctattact tctacttctt tgataggatt gtcaagtgga
    21841 ttaacagaga tacaaggaga tgttactagc aaattagttc ctgccagtca gtcgattgca
    21901 tcaggtgtaa acgcatatac tacaggtgtt gataaagttt ctcagggcgc aagtcaacta
    21961 agtgaaaaaa atgccacctt gacaggtagt ttggatcaac tagtttcagg ctcaaacacc
    22021 ttgacacaaa aatcttctag attaacagca ggagttggtt aattacaatc aggatctggg
    22081 caattagcag acaaatccag tcagttactt tcaggtgctt ctccattaga gaatagagct
    22141 aataaattgg cagatggatc tgggaaacta gcagaaggtg gaacaaagtt aacttctgga
    22201 ttggaagatt tacagacagg acttgcttct ttaggacaag gactaggtaa tgctagtgat
    22261 caactcaaat cagtatcaac agaatctaaa aatgcagaga ttttgtcaaa tccactcaat
    22321 ctttcaaaaa cagacaatga tcaagttcct gtaaatggaa tcgcaatagc tccttatatg
    22381 atatcagttg ctctttttgt tgcagcaata tcaacaaata tgatatttgc gaaattgcct
    22441 tcaggacgtc atccagagag ccgttgggct tggttgaaat cttgagctga aataaatggt
    22501 attatagctg ttttggcagg aattttggta tatggaggag ttcagcttat tggtttaact
    22561 gctaatcatg agatgagaat atttattctc atcatcctaa caagtttagt attcatgtct
    22621 atggtgacca ctttagcaac gtggaatagc cgtataggag cttttttctc acttattttg
    22681 cttttactac agttagcatc aagtgcaggt acttatccac ttgctttgac aaatgatttc
    22741 tttagatcta ttaatccctg gttaccaatg agctattcag tttcgggatt acgacaaaca
    22801 atctctatca acaagtcatt ttcctagctg tcatactagc tctatttact ggtttaggta
    22861 tgctagccta tcaacataag aaaatggaag aagattaaaa aaatcgaccg attaactggt
    22921 cgatttttta tgccttagat gactttcgtc tgtgattata gattccaaat agtaagagag
    22981 aagtaaagga acagattgct ccagtaataa aaccattggg aatgaaggaa agtgtaatag
    23041 ttcctttccc cttgggaatg tcaactttca taaatccagt ttgagcttgt ttaatttcta
    23101 ttttcttacc atcttggtag gcagaccaac ctttgtcata aggaatggtg aagaaaatag
    23161 atgtatcttg ttggacatca tatgtagcaa aaaccttgtt tttagaagtt gatactgtga
    23221 caggttgttc tttaattttt tgaattgcct cggtgaaagt tttggtatct aaacgataga
    23281 aggtaggaga ttcaaatgat acttgtgaat ttccagggaa actaacattg atattgaaag
    23341 tttttttctc tttagtatat cctagattaa agaaggagaa gacattatca gttgtaaaag
    23401 tctttttttc accatttaca aggatgtcaa ccttcttttg tttatcgtta gaaaagtgaa
    23461 ggtttatgaa agagagataa acttggctgt tttctggaac ttcaatttga tactggattg
    23521 ctgcatcttc atttgaagaa cttgtgacac taatcaaatc attagtattt tctatttttt
    23581 ctgttttttc ataaggtatt ggagaaaaat aatcaaaatt gacgttagca agttgattta
    23641 aaaatgaggc ctgattatcc aaggtatgtt cattgaactt gacatcattg taaacagatt
    23701 gactagcaac tgcaatcgga agagagtatt gattttcata tagggtaaga ttatcttttt
    23761 gatagatatc tttaaaacca tacttatcaa taggactgtc tgagatattg tactggatac
    23821 caaataaact atcagccaaa atactattat ttgcatatcg gagattgaga ttagtcccag
    23881 aggatttaaa accaagttta tctaaagtag agcttgatga acgatttcga acagatgaaa
    23941 attgagagat tccattgtag ttgaatttca tactgtcatt tcctgtctga gtttgtagtt
    24001 tttcagtacg agtaaattga tttccaatat atgttgagaa agattccata gctgggatat
    24061 ctcgactata agcacttcga gaagcaaatc cccattcctt agtaattccg tccatttgag
    24121 atgaagcatt taaactcatt tcaaccagta taaataaaga gattagaatg gcaaatagat
    24181 tcacagatat aaactttttg ataactgcaa ggagtaaaag agaatagaca accaaaaatt
    24241 caagagtaag cagaatattc aaatctgtta aaaaagaata atgcgatttt agatagatgg
    24301 tagctaaaaa tcctgttact acaagaaaaa gcgaaactaa aaaattccag actttaagtt
    24361 ctttcagacg ctttaagact tctgctgctg tgtaaattaa caaggtagag aaaatccaag
    24421 catagcgatg taaaaacatg tttggagtat gcatgccttg ccaaaataag tcaagagctt
    24481 ctatgtaaaa gcttgcaatt agaaatgcaa agaatattac atatatgagt ttcacgtgaa
    24541 acttaataga tttcagcgta aaaaataaaa tggtcaaaat aaagggaagt agtccaacaa
    24601 aaatcattgg gatggcccca tactttgttg tgtcaaagga accaatgaat tgcttagcaa
    24661 agagatcaag ataccagcta ctttcagttt gaaactttgt aacttcagtc aatttttccc
    24721 catgtgtctg taaatcaaac agagtgggaa gagtcataat caaactagct ataccagcta
    24781 aaaaggagat aactatgaaa tcaagaacag atgattttcg agtcttaaag tcccacgaaa
    24841 tttgacagag ataccagaaa ataagaaaca atactgtcat atatccaaaa taataatttt
    24901 gaataaataa gattgacaga cttgtaaagt acaataggag tttcttttca gttatcagta
    24961 gatgtaaacc agttataatt aaaggaatca agataaaaac atctagccag gtttttatct
    25021 ctaattgact gacagtgaaa ctcatcagag cataggaagt agataaggct agttttaaag
    25081 tctgagggat agattgaaac aatttattca aactaaaaaa ggttgacaga ccaatcaatc
    25141 caaattttaa gagagttgtc agatagatag catctggcat attcgttaga tcaaaaaagt
    25201 aaaccagagg tgagagaaaa ctacccaagt aataactaga tagagcatag aagtttagcc
    25261 ctagaccact tgtaaaggtg taaaccagac tactatttcc atgtaggata tttcgtaagg
    25321 ctatatcaaa aataacgtat tgatgaaagc catctcctaa tagaggagag ttgtcgctat
    25381 tccagtagat accttgagat agatatactc cagacataat cactacagga atgatgaaag
    25441 aaataaaata ggttcgatat gtttttaaaa atgatttcat gttacctcgt agaatgatag
    25501 aaaactcagt tggttaaccc aactgagttt tgaagtttta tttagtcttt ccaaagttct
    25561 ttaacttttg cttgtacttc tgcattttct aggaattcat cgtaggtttc atcgatacgg
    25621 tcaatgacgc catttttaga taagacaatg atatggttag ccaaagtttg aataaactcg
    25681 tggtcatggc tggcaaagat gattgattct ttaaagtttt tcaatccatc attcaagctt
    25741 gagatagatt ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac atttgatttt
    25801 aagagcatga gttttgaaag catgacacga actttttctc cccctgacaa gacatttaca
    25861 ggtttgttaa cttcatctcc agagaagagc atacggccga ggaagccacg taggaaagta
    25921 ttgtcatctt cttctttact tgcgaattga cgcaaccagt caagaattga ttctcctcct
    25981 gcaaaatcag ctgagttatc ttttggtagg taagattgac tagttgtaac tccccacttg
    26041 acagttcctt catagtcaat atctcccatg attgcacgaa ttaatgcagt cgtttgaata
    26101 tcattttgtc caataagtgc tgtcttatca tctggacgca agatgaaact aatattatcc
    26161 aagatagttt caccatcaat ctttacagtt agattttcta ctgtcaagag atcattacca
    26221 atctcacgtt ccgctttaaa gttgataaat ggatatttac gactagatgg tacaatctct
    26281 tctagctcaa tcttatcaag cattttctta cgtgatgttg cctgccttga cttagaagca
    26341 ttggcagaga aacgagcaac aaattcttgc aattgtttaa ttttttcttc tgctttagca
    26401 ttacggtctg ctagcaattt agcagcaagc tcagaagatt ccttccagaa gtcgtagttt
    26461 ccgacataga gtttgatttt tccaaagtca aggtcggcca tgtgagtaca aactttgttt
    26521 aagaagtgac ggtcgtggga tactacgata actgtgttat caaagtcaat caagaagtct
    26581 tctaaccaag taatcgagtg gatatccaaa ccgttagtag gctcgtccaa gagaagaaca
    26641 tctggtttac caaaaagtgc tttggcgagg agaaccttta ctttttcacc gttggccaat
    26701 tcgctcatgt tttggtagtg taattcttct ggaatgttta ggttttgaag tagttgagag
    26761 gcttcactct ctgcttccca acctccaagt tcggcaaatt ctccttcgag ttcggcagca
    26821 cgaaccccgt cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg
    26881 atgctataaa gtttttcatt tcccatgata acgacatcaa tggcacgttc atcttcgtag
    26941 tcaaagtgat tttgacgaag aacagagaga cgttcatctg gaccaagaga gatgtgacca
    27001 gtagtaggtt cgatatctcc agctaaaatt tttaaaaagg ttgattttcc ggcaccatta
    27061 gcaccgatta atccgtaagt atttccttct gtaaatttga tattgacatc atcaaaaagt
    27121 ttgcgatcac taaaacgtag tgaaacatca gatactgtaa gcaatatttt tctcctatat
    27181 gtgtaatata tttattctac tagaaaatac agaaatattc aaatttttat ttgtcaattt
    27241 tgtgtaaatt atatttacag tatcctttac acaaatctgt aaaaagcaag gctgatttat
    27301 tttgataaat tacggttatt tcattaaaaa aatgctataa ttgaaaggac tatatcgaag
    27361 gagaacaaaa tgactaaacc cattatttta acaggagacc gtccaacagg aaaattgcat
    27421 attggacatt atgttggaag tctcaaaaat cgagtattat tacaggaaga ggataagtat
    27481 gatatgtttg tgttcttggc tgaccaacaa gccttgacag atcatgccaa agatcctcaa
    27541 accattgtag agtctatcgg aaatgtggct ttggattatc ttgcagttgg attggatcca
    27601 aataagtcaa ctatttttat tcaaagccag attccagagt tggctgagtt gtctatgtat
    27661 tatatgaatc tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa gacagagatt
    27721 tctcagaaag gatttggaga aagcattccg acaggattct tggtctatcc aatcgctcaa
    27781 gcagctgata tcacagcttt caaggctaat tatgttcctg ttgggacaga tcagaaacca
    27841 atgattgagc aaactcgtga aattgttcgt tcttttaaca atgcatataa ctgtgatgtc
    27901 ttggtagagc cggaaggtat ttatccagaa aatgagagag cagggcgttt gcctggttta
    27961 gatggaaatg ctaaaatgtc taaatcacta aataatggta tttatttagc tgatgatgcg
    28021 gatactttgc gtaaaaaagt aatgagtatg tatacagatc cagatcatat ccgcgttgag
    28081 gatccaggta agattgaggg aaatatggtt ttccattatc tagatgtttt tggtcgtcca
    28141 gaagatgctc aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat
    28201 gtgaagacca agcgttatct acttgaaata ttagaacgtg aactgggtcc tattcgtgag
    28261 cgccgtattg aatttgctaa ggatatggga gaagtttata atatgattca aaaaggtagt
    28321 gaaagagcgc gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc aatgggactt
    28381 cattacttta actaagttta ttttacaaga aactatcatt tctatctcga agaaaagata
    28441 gttttttatt tacccctgta acatttgaca aatttttata gaatggtatg atagatacaa
    28501 tataaaaaga gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga
    28561 cactaaattt ttgaaaaaag gttttacctt tgatgatgta ttgcttattc cagctgaaag
    28621 tcatgtgttg cctaacgatg cagatttaac aactaaattg gcagataatt tgactttaaa
    28681 tatcccaatt attaccgctg ccatggacac agttacagag agtcaaatgg ccattgctat
    28741 tgctcgtgca ggtggtctcg gagttatcca taaaaacatg tcaattgctc aacaagcaga
    28801 cgaggttcgt aaggtaaaac gttctgaaaa tggagttatt attgatccgt tcttcttgac
    28861 gcctgaacat acaattgctg aagcagatga gcttatgggt cgttaccgca tcagtggtgt
    28921 tccagttgtt gaaacacttg aaaatcgtaa attggttggt attttgacaa accgagatct
    28981 tcgttttatt tcagattata atcaaccaat ttcaaaccat atgactagtg aaaatcttgt
    29041 tactgctcct gtgggtacgg atcttgcaac ggctgagagt attcttcaag agcatcgtat
    29101 tgaaaaactt ccgttggtcg atgaagaagg cagtctttct ggtttgatca ctatcaaaga
    29161 tattgaaaaa gttattgagt ttccaaatgc ggctaaagat gagtttggtc gtcttctagt
    29221 tgcaggtgca gtaggtgtta cttcagatac atttgaacgt gcagaggctc tttttgaggc
    29281 aggagcggat gcgattgtta ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa
    29341 aattgccgag attcgtgctc atttcccaga tcggactttg attgctggaa atattgctac
    29401 tgctgaaggt gcacgtgccc tttatgaagc gggtgtagac gttgttaagg ttggtattgg
    29461 accaggttct atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc
    29521 tatctacgat gctgcagctg ttgcgcgcga atatggtaaa acgattattg ctgacggtgg
    29581 gatcaagtat tctggagata ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct
    29641 tggatctatg tttgctggaa ctgatgaagc tccaggcgaa actgaaatct tccaaggacg
    29701 taaattcaag acttaccgtg gtatgggatc aattgctgct atgaagaaag gttcaagcga
    29761 ccgttatttc caaggttctg tcaatgaagc aaacaagctt gttccagaag gaattgaagg
    29821 tcgtgttgct tataaaggag cggcagctga tattgttttc caaatgattg gtggtattcg
    29881 ctctggtatg ggttactgtg gtgcagctaa ccttaaagaa ctacacgata atgctcaatt
    29941 tattgaaatg tctggtgctg gtttgaaaga aagccatcct catgatgtgc aaattactaa
    30001 tgaggcacca aattattcta tgtaaaaaac aatgaaaaga actccagtga aaacaggagt
    30061 tcttttacaa tgttgtcaat ttccatttac agcagcttta ccatcctgaa tagtgaagat
    30121 acttagattt tctggcagat tttgaagatg gtctaagctt gttgttgtga taaaggtttg
    30181 gattgattga gaaatcgttt ctaataattt taactgtcta gtgttgtcaa gttcactcat
    30241 cacatcgtca agcagtaata tcggagattc tgtggtaatg ctttccatta attcgatttc
    30301 tgctaatttt atcgagagga cgagactacg atgttgacct tggcttccga aactagcatc
    30361 catcccattt atataaaaag aaatgtcatc tcgatgagga ccgacaccag tattcttttt
    30421 aaataaatct ctggatctac ttttttctaa agcaattttg aaagattcgg ataagttttg
    30481 tttgtcagtt atattgacag aagattgata ggatattgac aactcttcga tctgattaga
    30541 gagttcaaaa tgtttcttac gcccaaatga ttctagtttt tttatgaaat ctaagcggtg
    30601 attcattaca cgacatccat aatcaactag ctgatcatct aacacagaaa ggaatgtttc
    30661 atctattttt tgatctgatt ttaggtaagt gtttctttgc tttaggatgt ggttataatt
    30721 ggttaagtca gataagtaga ttggcttaat ttgcccaagt tccatatcaa tgaattttcg
    30781 tcgaatcgaa ggtgctcctt taattagttg taaatcttca ggagcaaata agacaacatt
    30841 catgtgtcct acataatctg aaagtcgtgc ctgttttaag tgattaactt ttgttacacg
    30901 gcctttttgt gttagttcga tttctagggg aatggatcca gtttttttct gaacgagacc
    30961 tgaaagatga agttgttctt catcaaaatg aatgagattt ttatctgttc gagttcgatg
    31021 actacgcgtt aaggctaaaa aatagatagc ctctaacatg tttgtttttc cttgtgcatt
    31081 acgtcccaaa aagacattca atttaggatt aaagtctatt ttcgtttctt tgtaattacg
    31141 aaaagtcttg agagatagat gttgtagcca catgattatc taccagggaa tcgtggagct
    31201 tgttggcttt taggtgatga agcaggtttc gatttgtctt ttttaactcc cttattcatc
    31261 tttttgacaa gtttagcgat ccgttctttt tcaactttat cagcttggta ttcatcttgt
    31321 tcttcagaag taggttgtgt caacaagatg tcaatgttca tgtcagggat gtcaacttta
    31381 tcgccaatac gaagtttttt tccacgacga ctctctaatt ccctattaaa gtaaacagaa
    31441 tgttcagaga gaaatgattt aatagctcct ccgctatgtg taattccaag ttctttgagt
    31501 agtgcttgga gggtaataaa ttcttcaaat aatttgtatt ccataattca cctcaatctt
    31561 tggtattata ccatattttc ctaaaaatag tgagagagac agagagaaat gtaagcgatt
    31621 tttatttcaa aagtgttaca gggaacaaga aaatttcagg ttttcgtgat ataatagaag
    31681 tctgtatata aggaggtaaa tcatggagtt agtgcatgga atttcaacac attttatcca
    31741 atcaaaaaag tttaaaacaa acaaaattac cgtgcgtttt accgctccat tatcccttga
    31801 tacgattgca ggtcacatgt tgagtgcaag tatgctagag actgctaatc agatgtaccc
    31861 cacttctcaa gatttgagga gacacttggc cagtctatac ggtacagata tgtcaaccaa
    31921 ttgtttcaga agagggcaaa gccacattat agaattgaca tttacctatg ttcgtgatga
    31981 gtttttaagt aggaaaaacg tgctaacctc tcagattttg gaacttgtaa aagaaactct
    32041 tttttcaccc gtagtagttg ataatgggtt tgatccgccc ttatttgaaa ttgagaaaaa
    32101 acaattgcta gcaagtttag cagctgatat ggatgattct ttttattttg cacataaaga
    32161 attggataaa ttgttttttc atgatgaacg tcttcaattg gaatatagtg atttacgaaa
    32221 tcgtatttta gctgaaactc cacaaagttc ttattcttgt ttccaagaat ttttagccaa
    32281 tgatcgaata gatttctttt tcctaggtga ttttaatgag gttgaaattc aaaatgtatt
    32341 agaatcattt ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta
    32401 ttctaatatc cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt
    32461 aggttatcat taccgttcta aatatggtga tgagcaacat ttacccatga ttgtaatgaa
    32521 tggtttactt ggtggatttg ctcactctaa gctctttaca aatgtccgtg aaaatgctgg
    32581 attagcttat accatttcaa gtgagcttga tttatttagt ggattcttga ggatgtatgc
    32641 tggtatcaat cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc aactgcttga
    32701 tttaaaaaaa ggttatttta cagagtttga gttaaatcag accaaggaaa tgattcgttg
    32761 gtcgttgtta ctttctcaag ataatcaatc ttcattgatt gaacgtgctt atcaaaatgc
    32821 cttatttgga aaatcttcag cagactttaa aagttggatt gcaaagcttg aacaaattga
    32881 caaagatgct atttgtagag tagctaataa tgtgaaacta caagcgattt actttatgga
    32941 aggaatagaa tgacaaaggt tgtttttgaa gaaaaatact atccagctgt aaaagaaatg
    33001 gtttatcgaa ctcgtttggc caacggattg acagttgctc ttttgcctaa aaaggaattt
    33061 aaagaggttt acgggagtgt cactgtacag tttggttcgg tagatacgtt tgtcacagaa
    33121 gttgacggag atgtaaaaca atatcctgga ggaattgctc attttcttga acataaatta
    33181 tttgagagag aagattctag tgatttgatg tcggctttta cgagtctagg tgcagatagt
    33241 aatgccttta caagctttac aaaaacaaac tatctttttt cagcaacgga ttgtttttta
    33301 gaaaatttag atttacttga tgaattggta acatcagcac actttactga agcttccatt
    33361 ctgacagagc aggatattat tcagcaagaa cgagaaatgt accaagatga tccagattcg
    33421 tgtttattct tttcaacttt agcgaatttg tatcctggta cacctttagc aactgatata
    33481 gttggaagtg aggagtccat gtcccaaatc aatctaacta atttgcaaga aaattttaca
    33541 aagttttaca aacctgtaaa catgtctctg tttttagttg gtaattttga tgtggagcga
    33601 gtacaggact attttgaaag caaagaactg aaagattcag attttcagga agtagcaaga
    33661 gaaaagttgt ttttacagcc tgtaaagcca acagatagta tgagaatgga agtatcttct
    33721 cccaaactag cgattggagt tagaggtaag cgagaagttt ctgaagcgga ttgctatcga
    33781 catcatattt tattaaaatt attgtttgca atgatgtttg gttggacttc ggatcgtttt
    33841 caaaaatgtt atgaatcagg taaaattgat gcgtccttat ctctggaagt tgaaataaca
    33901 agtcgctttc attttgtcat gttgacaatg gatacgaaag agccagttgc tttgtctcat
    33961 caatttagga aggctattcg taattttaca aaggatttag atattacaga ggaacattta
    34021 gatattatca aaagagagat gtttggcgaa tttttcagta gcatgaactc tcttgaattt
    34081 attgcaacgc aatatgatgc ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt
    34141 ttacaggaaa ttactttaga ggatgtcctt gatgctggac atcatttaat agatgatggt
    34201 gacatagttg attttacaat attcccatcg tagtaaccta tcataataga cactagaaag
    34261 aagggatgac aagtatgaga aaaaaaacaa ttggagaggt tttacgatta gctagaatca
    34321 atcagggatt gagtttagat gaattgcaga aaaagacaga aatccagtta gatatgttgg
    34381 aagcaatgga agcagacgat ttcgatcaac ttccaagtcc tttttacacg cgttctttct
    34441 tgaaaaaata tgcatgggct gttgagttag atgaccaaat tgttttggat gcttatgatt
    34501 ctgggagtat gattacttat gaggaagtag atgttgatga agatgagttg acaggtcgta
    34561 gacgttcaag taagaaaaag aagaaaaaaa catcattttt acctttattt tattttatcc
    34621 tttttgcttt atcgatttta atttttgtga cttattatgt ttggaactat attcaaactc
    34681 aaccagagga gccttctctt tctaattaca gtgtggttca atcaacaagt tcaactagct
    34741 ctgttcccca ctcctcaagt agtagttctt ctagtataga atcagctata agtgtatcag
    34801 gcgaaggaaa tcatgtagaa atcgcttata agacaagtaa ggaaacagtt aaattgcaat
    34861 tggcagtttc agatgttaca agttgggtca gtgtttcaga aagcgaactt gagggcggtg
    34921 taaccttatc gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa
    34981 caattacgtt aggtgttgta aaaggtgttg atttgacagt agataatcag actgttgatt
    35041 tatcgaaatt aacagctcag actggacaaa tcactgtaac ctttactaaa aattaaggaa
    35101 aaacgaatga aaaaagaaca aattcccaat ctcttaacaa taggtcgaat tctctttata
    35161 cctattttta tctttatttt aacgatagga aattcgatag agagtcatat agttgcagct
    35221 attatctttg ctgttgccag tattaccgac tatttagatg gatatttagc tcgtaaatgg
    35281 aatgtggtca gtaattttgg taaatttgca gatcctatgg cggataagtt actagttatg
    35341 tcggctttta ttatgttgat tgagttaggt atggctccgg cttggattgt tgcagtgatt
    35401 atctgtcgtg agttagctgt gacaggttta aggcttttat tggttgaaac tggtggaaca
    35461 attttagcag cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt tgccattatt
    35521 ttcttgctat tacattggac tttgcttggt caagttctac tttatgtagc cttatttttc
    35581 actatctact ctggctatga ctatttcaag ggtagtgcct atgtatttaa agggacattt
    35641 ggttcgaaat gaaatcaata attgatgtaa aaaatctttc ttttcgctat aaagaaaatc
    35701 agaactacta cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa tggctttcga
    35761 ttgtagggca taatggtagt ggtaaatcaa cgacggttcg attaattgat ggcttactgg
    35821 aagcagaatc cggagagatt gtaattgatg gccaacgttt gactgaggaa aatgtttgga
    35881 atatacgtcg tcaaatcggt atggtttttc aaaatccaga caatcaattt gttggagcga
    35941 ctgttgaaga tgatgttgct tttggtttgg aaaatcaggg actttctcgt caagaaatga
    36001 aaaagagagt ggaagaagct ctggctttag ttggcatgtt ggactttaaa aagagagagc
    36061 cagcgcgtct atcaggtggc caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa
    36121 gaccagttat tttaatctta gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag
    36181 aacttattgg gacagtaaaa ggaattcgaa aagactatga tatgacggtc atttctatta
    36241 cccatgattt ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa
    36301 ttgaatcaac tagtagtcca agggagcttt tctctcgaaa tgatttagat caaattggat
    36361 tagacgatcc ttttgctaat caattaaaaa aatctttgag ccagaatggc tatgatttac
    36421 ctgaaaatta tttgacagaa agtgagctag aggataagct atgggaattg ctctagaaaa
    36481 tgtgaatttt acatatcaag aaggtactcc cttagcttca gcagctttgt cggatgtttc
    36541 tttgacgatt gaagatggct cttatacagc tttaattggg cacacaggta gtggtaaatc
    36601 aactatttta caactcttaa atggtttatt ggtgccaagt caagggagtg tgagggtttt
    36661 tgatacctta atcacctcga cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt
    36721 tggcttggta tttcagtttg ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt
    36781 tgcttttgga ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga
    36841 gaaactggct ctggttggaa ttgatgaatc actttttgat cgtagtccgt ttgagctgtc
    36901 agggggacaa atgagacgtg ttgccattgc aggcatactt gccatggagc cagctatatt
    36961 agtcttagat gagccaacag ctggtctaga tcctctaggg agaaaagagt tgatgaccct
    37021 gttcaaaaaa ctccaccagt cagggatgac catcgtcttg gtaacgcatt tgatggatga
    37081 tgttgctgaa tatgcaaatc aagtctatgt aatggaaaag ggacgtttag taaagggggg
    37141 caaaccaagt gatgtctttc aagacgttgt ttttatggaa gaagttcagt tgggagtacc
    37201 taaaattacg gccttttgta aacgattggc tgatagaggc gtgtcattta aacgattacc
    37261 gattaagata gaggagttca aggagtcgct aaatggatag tatgattttg gggcgttata
    37321 tcccagggga ttcgattgtt caccgattgg atccacgtag caaattgctt gctatgatgc
    37381 tactgatttt gattgtgttt tgggctaata accccttgac gaatctgatt ctttttatag
    37441 cgacagggat atttattgcc ttgtcaggag tatctctttc attttttatt cagggcttga
    37501 agtctatgtt tttcttgatt gccttcacaa ctatttttca actatttttc atttctaatg
    37561 ggaatgtttt atttgagttt tcgtttgtga gaatcacgga ttatgctttg caacaagctg
    37621 ggattatttt ttgtcgcttt gtattgatta ttttcttttc aactttgtta accttaacaa
    37681 ccatgccttt aagtttggca tcagctgtcg aagctttatt agcaccttta aagcgtgtga
    37741 aagttccagt tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt gtcccaacct
    37801 tgatggatga tacgactcgg attatgaatg cacagaaagc tcgtggagtg gattttggag
    37861 aaggaagcat cgttcaaaaa gtaaaggcga tgattcccat tttgattcct ctttttgcga
    37921 caagtttaaa acgtgcagat tccttggcta tcgctatgga agcgcgtggc tatcagggtg
    37981 gaaaaggcag aagtcaatac cgacaattga aatggactct aaaggatacg ctgaccattc
    38041 ttgttattct cgtacttggt tgttgtttat ttttcttaaa atcttagtag ctttcaggaa
    38101 ttgataaaaa gttactgtaa cagtttttga tataaaggta gggatatgaa ccgttttaaa
    38161 aaatcaaaat atgtcattat tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg
    38221 acgacttatt caagtacaat tgtgacaaaa ttaggagatg gaatctcatt ggttgataga
    38281 gttgtacaaa aaccttttca gtggtttgat tctgtcaaat cagatttggc tcatttgaca
    38341 cgaacatata atgaaaatga aagtttgaag aaacagcttt accaattaga agttaaatca
    38401 aatgaggtgg aaagtttaaa gacagaaaat gaacaactgc gccaattgct tgatatgaag
    38461 tctaaattgc aagccacaaa gactttagca gcagatgtta ttatgcgttc tccggtatct
    38521 tggaagcagg agttgacctt agatgcaggt agatcaaaag gtgcttctga gaacatgtta
    38581 gctattgcaa atggtggctt gattgggagt gtttcaaaag tagaggagaa ctctactata
    38641 gtcaaccttc tgacaaatac ggaaaatgct gataagattt ctgttaaaat tcaacatggc
    38701 tctactacaa tttatggaat tattattggc tatgacaagg aaaatgacgt tcttaaaatt
    38761 agccaattaa atagtaatag cgatattagt gcgggagata aggtgactac tggtggatta
    38821 ggaaacttta acgttgttga tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca
    38881 gactatttga cacgagaagt aactgttaaa ttgagtgcag atactcataa tgtagatgtg
    38941 atagaattag tggggaattc ataatgagac agttgaagcg agttggagta tttttattgc
    39001 ttcctttctt tgttctaatt gacgcccata ttagccagct tctgggctca tttttccccc
    39061 atgtacattt ggctagtcat tttctttttc tatttctctt atttgagacg atagaagtat
    39121 cagagtatct ctacctagtc tattgttttg ttataggctt ggtttatgat gtttactttt
    39181 tccatctaat agggattaca actctcttat ttatcttatt gggagccttc cttcataaat
    39241 tgaatagtgt tattttgttg aatcgttgga caagaatgct agctatgatt gtgctgacat
    39301 tcctgtttga aatgggtagt tatcttttgg cttttatggt agggttgaca gtagatagca
    39361 tgtcgatttt tatagtctat agcttggtac cgacgatgat tttaaatttt ttatggatta
    39421 ctgtttttca atttattttt gaaaaatatt atctataaga acgacatata aatgtaacaa
    39481 aggcgtaata tttattaggc ctttttttgg tatactagta ttgtctttaa aagaaggagt
    39541 atctacgtaa tatgaagaaa aaaatcttag cgtcactttt attaagtaca gtaatggttt
    39601 ctcaagtagc tgttttaaca actgcgcatg cagaaacgac tgatgacaaa attgctgctc
    39661 aagataataa aattagtaac ttaacagcac aacaacaaga agcccaaaaa caagttgacc
    39721 aaattcagga gcaagtatca gctattcaag ctgagcagtc taacttgcaa gctgaaaatg
    39781 atagattaca agcagaatct aagaaactcg agggtgagat tacagaactt tctaaaaaca
    39841 ttgtttctcg taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca aatggagccg
    39901 taactagcta tatcaatacc attgtaaact caaaatcaat tacagaagct atttcacgtg
    39961 ttgctgcaat gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa caaaaggcag
    40021 ataaaaaagc tatttctgaa aaacaagtag caaataatga tgctatcaat actgtaattg
    40081 ctaatcaaca aaaattggct gatgatgctc aagcattgac tacgaaacag gcagaactaa
    40141 aagctgctga attaagtctt gctgctgaga gagcgacagc tgaaggggaa aaagcaagtc
    40201 tattagagca aaaagcagca gctgaggcag aggctcgtgc agctgcggta gcagaagcag
    40261 cttataaaga aaaacgagct agccaacaac aatcagtact tgcttcagca aacactaact
    40321 taacagctca agtgcaagca gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc
    40381 gtccaacata cagtacaaac gcttcaagtt atccaattgg agaatgtaca tggggagtaa
    40441 aaacattggc accttgggct ggagactact ggggtaatgg agcacagtgg gctacaagtg
    40501 cagcagcagc aggtttccgt acaggttcaa cacctcaagt tggagcaatt gcatgttgga
    40561 atgatggtgg atatggtcac gtagcggttg ttacagctgt tgaatcaaca acacgtatcc
    40621 aagtatcaga atcaaattat gcaggtaatc gtacaattgg aaatcaccgt ggatggttca
    40681 atccaacaac aacttctgaa ggttttgtta catatattta tgcagattaa tttacagagg
    40741 gactcgaata gagccctctt ttcaggtttt accgtgacaa tccctattaa aaattatatc
    40801 aaaatagctt gaaaatattg gaaaagtatg gtagaatgaa aattgtcgtg tgaacgataa
    40861 tactcattct tgatgaattg tgaagcagtt gcccttgggt cgttttgcga gttgaagtca
    40921 agaagaggaa aaaaacaaaa aggagaaata ctcatggcag taatttcaat gaaacaactt
    40981 cttgaggctg gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa gatggctaag
    41041 tacatcttta ctgaacgtaa cggaatccac gttatcgact tgcaacaaac tgtaaaatac
    41101 gctgaccaag catacgactt catgcgtgat gcagcagcta acgatgcagt tgtattgttc
    41161 gttggtacta agaaacaagc agctgatgca gttgctgaag aagcagtacg ttcaggtcaa
    41221 tacttcatca accaccgttg gttgggtgga actcttacaa actggggaac aatccaaaaa
    41281 cgtatcgctc gtttgaaaga aattaaacgt atggaagaag atggaacttt cgaagttctt
    41341 cctaagaaag aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggc
    41401 ggtatcgaag atatgcctcg tatcccagat gtgatgtacg tagttgaccc acataaagag
    41461 caaatcgctg ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat ggttgacacc
    41521 aatactgatc cagatgatat cgatgtaatc atcccagcta acgatgacgc tatccgtgct
    41581 gttaaattga tcacagctaa attggctgac gctattatcg aaggacgtca aggtgaggat
    41641 gcagtagcag ttgaagcaga atttgcagct tcagaaactc aagcagattc aattgaagaa
    41701 atcgttgaag ttgtagaagg tgacaacgct taatttatac aaatagtaat tacctaggag
    41761 ggcggggctt agcccggctc tcctattttc aaaaaatata ggagaattaa aatggcagaa
    41821 attacagcta aacttgtaaa agagttgcgt gaaaaatctg gtgccggtgt tatggacgct
    41881 aaaaaagcgc ttgtagaaac agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa
    41941 aaaggtatgg ctaaggcagc taagaaagct gaccgtgttg ctgcagaagg tttgactggt
    42001 gtttatgtta acggtaatgt tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt
    42061 gcaaaaaacg ctcaattcgt tgaattggta aatactacag ctaaagtcat tgctgaagga
    42121 aaacctgcta acaatgaaga agctcttgct ttgataatgc cttcaggtga aactcttgaa
    42181 gctgcatacg tatctgcaac agcaactatc ggagagaaaa tctcattccg tcgctttgca
    42241 ttgattgaaa aaacagacgc acaacacttt ggagcatacc aacataacgg tggacgtatc
    42301 ggtgttattt cagttgttga aggtggagac gaagcacttg ctaaacaatt gtcaatgcac
    42361 atcgcagcga tgaaaccaac agttctttct tacaaagaat tggatgagca attcgttaaa
    42421 gatgagttgg cacaattgaa tcacgttatc gaccaagaca acgaaagccg tgcaatggtt
    42481 aataaaccag ctcttccaca cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt
    42541 attgctcaag ctgaagctga catcaaagct gaattggctg cagaaggcaa accagaaaaa
    42601 atctgggaca aaattattcc aggtaaaatg gatcgcttca tgcttgataa cactaaagtt
    42661 gaccaagctt acacacttct tgcacaagtt tacatcatgg atgacagcaa gacagttgaa
    42721 gcataccttg aatcagttaa cgcttcggta gttgagtttg ctcgctttga agttggtgaa
    42781 ggtatcgaga aagctgcaaa cgacttcgaa gctgaagttg cagctacaat ggcagcagcc
    42841 ttgaataact aataatagaa aggaagcaat ttgcttcctt ttttgtatag ggcttatatt
    42901 tttcctgaaa ttgtttttcc cccagtctca ctcgattaga ataattaaaa caaaaagccc
    42961 tataataagg gctaagtgca tttaggagac tatacttcaa attcatagta agcgcgtcat
    43021 aacaaggtat ctatcctaat tccccaactt ccagtatact agataaaaaa taattatcgg
    43081 aggaaaggta ttgtactatg atgattcaac taagtgattt aggtcaagtt cacattgttt
    43141 gtggcaagac agatatgagg cagggaatag actcattagc ctatgtagtt aaaacccact
    43201 ttgaattgga ttctttctcc ggtcaagtct ttctcttttg tggtggacgt aaagaccgct
    43261 ttaaagtcct ttactgggat ggtcaaggat tttggctact atataaacgc tttgagaacg
    43321 gaaaactgac ttggctaagt acagaaaagg atgtcaaagc tctcacatct gaacaagtag
    43381 attggcttat gaagggcttt tctatcactc caaaaatata gtagattgaa actagaatag
    43441 tacacctctg cttctaaaac attgttagaa atcgatttga ttgtcctgat cgatttgtcc
    43501 tgttcttatt tcattttact ataaatccat cagaaagttg tgatttctat tgaaatgagg
    43561 actttctttt tacactcatc tgctttcaaa aagcattcta gtccatctcc gattaacgat
    43621 ggactttatc acctccttct ccagtccttg tatgacatct tccaaagttc gaaaggcttt
    43681 attcttaaat ccacgtttac gaatctcttt ctacacttgt tcaatggggt tcatctctgg
    43741 tgtgtatgga ggaataaatg caaagccaat attagtcgga atctttaagg tacttgattt
    43801 atgccatata gcattgtcca taacgagtaa aagataatca tctggataag cttgtgaaag
    43861 ctcctattcc taaagcccct ttagcgcata gctttggctc agcttctatt atcgctcaca
    43921 ccatccatca gaagtttaat ctgaaggtac ccaattatcg ccaagaagaa gattgggcta
    43981 agatgggttt accaatcaca cgcaaggaaa tctctaattg gcatatcaag acgagtcaat
    44041 actatttgga gcccctctat aacctcttgc gagagagact attgactcag cccttacttc
    44101 atgcggatga aacttcttat agggtgctag agagtgatag tcagctgact tactattgga
    44161 cttttttgtc tgggaaagct gagaaacaag ggattacgct ttaccatcat gtcctaatcg
    44221 atttgttcat atcttatttc aatccattat aaatagtgag aaatatctat cctatcttct
    44281 agaatgtctt ccaaacgtgg aaactctcgt aaacaaagag gttttagagg cttatttacc
    44341 atggactaaa gttgtacaag aaaagtgcaa ataagaaatc tccagattag gaactatccg
    44401 tgagttctct agtctggaga tttttcaata tacttcgtta ttggacggtt acaattcata
    44461 aagtgctgta gagagataac gttcaccgtt atctggtgct aggacaagga cttttttacc
    44521 tgtacctaat tttttggcaa cctcgatggc tccgtagata gctgcagctg aggaaatccc
    44581 tacaaggaag ccttcttttc caccaatttc acgtccgagt gcaagagcgt catctgatgt
    44641 tacacgaacg ataccatcat aggctttagt atcaagtgta tcaggaataa atccagctga
    44701 gataccttga attttgtgag gaccaggttt ttcaccagat agaatagcag attcatctgc
    44761 ttctactgca aaaacttgaa tgttagaatt ttctgatttg agtgcatgag aaacaccaga
    44821 aatcgttcca ccggtaccta ctccagcaac aaaggcatct aatccatctt taccgaaagc
    44881 agctagtatc tcagctcctg ttgttctttc gtgtacttct ggattagctg gattgtcaaa
    44941 ttgaagagga aggaaaccat cacgttcagc agcgatttct tgagccttag caatagcacc
    45001 tttcattccc tcgctaccag gagttaggac gagttcagca ccataagctt ggataatttt
    45061 acgtcgttct acactcatag tttcaggcat aacgatgacg actttatacc ctttagcagc
    45121 acctacccat gaaagtccaa taccagtgtt tccacttgtt gcttcaacaa tagtagaacc
    45181 aggtttcaga ataccatctt gttcagcttt ttcaatcatg ctaagggcaa tacggtcttt
    45241 tacagatgaa ccaggattaa atgcttcaag ctttatatag acgtctgcag caccttctgg
    45301 cacgatgttg ttaagtttaa caatcggtgt ttgaccgatt aattcagtaa tgttgttata
    45361 aatagacata tgaatacctc tttgtataag atatctttag tataacgcta tctataccat
    45421 ttgtaaaata tagaaatcct atcgaagcga taggatttct atatatcata gatcaaagtc
    45481 attaattttc aagtgattgc gttcagctaa ttctagtaaa taggtgtgaa ggaaaacgat
    45541 atcaggtttc gtttgaattg cttcattttc tagtatattt tggtacgcat ctttttattt
    45601 tgctcgctaa agtagttgtg agaatgtcaa cgaaacgctg tattattcat tgtttacact
    45661 aagtttacag gaacttcaac ctctcgtaaa ccttggtcag ttaaagtgac ttttccatta
    45721 aaaaactcca caagtgcagc tttaatagtt tctttttctt ccttatcaac ataaatcatc
    45781 gtatcgactt gatctgtaaa gtttgtatcc agctccatga gatcatgttc tttaaggaag
    45841 ttactgtact cttggtactg agcataagac atttgaatag caatgccagc ctgttctttt
    45901 atttcaataa taccaatttc tttgacagct aaggcgacac tgccggcgta agcacgaatt
    45961 agtcctccag cgcctagttt aataccacca aagtagcgtg tcacgaccac acagacattg
    46021 gtgagattgt gattttctag taccccaagc atgggaacac cagcagtacc actaggctca
    46081 ccatcatcac ttgtacgttt aatttcacta cgttctccaa taataaaggc agagcagtta
    46141 tgtgtcgctt tgtagtgttc ttttttgatg gcagtaatga agtcacgagc ctcttcttcg
    46201 ctataaacac gcttggcatg gcagataaag cgagattttt tgatttcttc ttggacttgg
    46261 ccgtcctctt taattgtcct aaattccatg atttaattgt actaaaaaat aatctaaagt
    46321 gctagttttt acgaataaag aagtatgaaa gtaaatttag attatctcgg tcgtttattt
    46381 actgagaatg aattaacaga agaagaacgt cagttggcgg agaaacttcc agcaatgaga
    46441 aaggagaagg ggaaactttt ctgtcaacgt tgtaatagta ctattctaga agaatggtat
    46501 ttgcccatcg gtgcttacta ttgtcgagag tgcttgctga tgaagcgagt cagaagtgat
    46561 caaactttat actattttcc gcaggaggat tttccgaagc aagatgttct caaatggcgc
    46621 ggccaattaa ctccttttca agagaaggtg tcagagggac tgcttcaagc agtagacaag
    46681 caaaagccaa ccttagttca tgcggtaaca ggagctggaa agacagaaat gatttatcaa
    46741 gtagtggcta aagtgatcaa tgcgggtggt gcagtgtgtt tggctagtcc tcgcatagat
    46801 gtttgtttgg agctgtacaa gcgcctgcaa caggattttt cttgcgggat agctttgcta
    46861 catggagaat cggaacctta ttttcgaaca ccactagttg ttgcaacaac ccatcagtta
    46921 ttgaagtttt atcaagcttt tgatttgctg atagtggatg aagtagatgc ttttccttat
    46981 gttgataatc ccacgcttta ccacgctgtc aagaatagtg taaaggagaa tggattgaga
    47041 atctttttaa cagcgacttc gaccaatgag ttagataaaa aggtccgttt aggagaacta
    47101 aaaagactga gtttaccgag acggtttcat ggaaatccgt tgattattcc aaaaccaatt
    47161 tggttatcgg attttaatcg ctacttagac aagaatcgtt tgtcaccaaa gttaaagtcc
    47221 tatattgaga agcagagaaa gacagcttat ccgttactca tttttgcttc agaaattaag
    47281 aaaggggagc agttagaaga aatcttacag gagcaatttc caaatgagaa aattggcttt
    47341 gtatcttctg taacagagga tcgattagag caagtacaag cttttcgaga tggagaactg
    47401 acaatactta ttagtacgac aatcttggag cgtggagtta ccttcccttg tgtggatgtt
    47461 ttcgtagtag aggccaatca tcgtttgttt accaagtcta gtttgattca gattggtgga
    47521 cgagttggac gaagcatgga tagaccgaca ggagatttgc ttttcttcca tgatgggtta
    47581 aatgcttcaa tcaagaaggc gattaaggaa attcagatga tgaataagga ggctggtcta
    47641 tgaagtgctt gttatgtggg cagactatga agactgtttt aacttttagt agtctcttac
    47701 ttctgaggaa tgatgactct tgtctttgtt cagactgtga ttctactttt gaaagaattg
    47761 gggaagagaa ctgtccaaat tgtatgaaaa cagagttgtc aataaagtgt caagattgtc
    47821 aactttggtg taaagaggga gttgaagtca gtcatagagc gatttttact tacaatcaag
    47881 ctatgaagga ttttttcagt cggtataagt ttgatggaga cttcctgtta agaaaagttt
    47941 tcgcttcatt tttaagtgag gagttgaaaa agtacaaaga gtatcaattt gttgtaattc
    48001 ccctaagtcc tgatagatat gctaatagag gatttaatca ggttgagggc ttggtagagg
    48061 cagcaggctt tgagtatctg gatttattag agaaaagaga agagagagcc agttcttcta
    48121 aaaatcgttc agagcgcttg gggacagaac ttcctttctt tattaaaagt ggagtcacta
    48181 ttcctaaaaa aatcctactt atagatgata tctatactac aggagcaact ataaatcgtg
    48241 ttaagaaact gttggaagaa gctggtgcta aggatgtaaa aacattttcc cttgtaagat
    48301 gaggaaaaaa tttgcaaaaa tagaatgaaa gcgttataat aaaatcataa aaacaaaaat
    48361 gtttagaaag aaggtactca tatgattaaa tatagtatcc gtggtgaaaa cctagaagta
    48421 acagaagcaa ttcgtgatta tgtagtttct aaactcgaaa agatcgaaaa gtacttccaa
    48481 ccagaacaag agttggatgc ccgaattaac ttaaaagttt atcgtgaaaa aacggctaaa
    48541 gtggaagtaa cgattccgct tggatctatt actctccgcg cagaagatgt atctcaagat
    48601 atgtatggtt caattgacct tgtaactgat aaaattgaac gtcagattcg taaaaataaa
    48661 acaaaaatcg agcgtaaaaa taaaaataag gtagcaactg gtcaattatt tacagatgct
    48721 ttggtggaag attcaaatgt tgtccagtct aaagttgttc gttcaaaaca aattgattta
    48781 aaaccaatgg atttggaaga agcaattcta caaatggatt tattggggca tgatttcttt
    48841 atctatgtgg atgttgaaga tcagacaacc aatgtgattt atcgtcgtga ggatggcgaa
    48901 attggtttgt tagaggttaa agaatcttaa tttcaatatg tgtaaaggta ggtttactga
    48961 attgtaaact acctttttct tataattgat agaattactg attacacttt taaaaagtcg
    49021 ctttttgagg ggtattatgg tataatgggt gccaagaggt tttgaatgaa aaaattttat
    49081 gtaagtccaa tttttcctat tctagtagga ttgattgcgt ttggagtctt atccactttc
    49141 attatttttg ttaataataa tctgttgacg gttttaattt tgtttctttt tgtaggaggc
    49201 tatgtttttt tatttaagaa actgagagtg cattatacaa ggagtgatgt agaacagata
    49261 cagtatgtaa accaccaagc ggaagaaagt ttgacatctc tattggaaca aatgcctgta
    49321 ggtgttatga aattgaattt atcttctgga gaggttgagt ggtttaatcc ctatgctgaa
    49381 ttgattttga ccaaggaaga tggtgatttt gatttagaag ctgttcaaac gattatcaag
    49441 gcttcagtag gaaatccgtc tacttatgcc aagcttggtg agaagcgtta tgctgttcat
    49501 atggatgctt cttccggtgt tttgtatttt gtagatgtat ccagggaaca agccataaca
    49561 gatgaattgg taacaagtcg accagtgatt gggattgtct ctgtggataa ttatgatgat
    49621 ttggaggatg caacttctga gtcagatatt agtcaaatca atagttttat agctaatttt
    49681 atatcagagt tttcagaaaa acacatgatg ttttctcgtc gggtaagtat ggatcgattt
    49741 tatctattta ctgactacac ggtgcttgag ggcttgatga atgataaatt ttctgttatt
    49801 gatgctttca gagaagagtc gaaacagaga cagttgccct tgaccttaag tatgggattt
    49861 tcttatggcg atggaaatca tgatgagata gggaaagttg ctttgctcaa tttgaacttg
    49921 gctgaagtac gtggtggcga ccaggtggtt gttaaggaaa acgacgaaac gaaaaatcca
    49981 gtttattttg gtggtgggtc tgctgcttca atcaagcgta cacggactcg tacgcgcgct
    50041 atgatgacag ctatttcaga taagattcgg agtgtagatc aggtttttgt agtcggtcac
    50101 aaaaatttag acatggatgc tttgggctct gctgtaggta tgcagttgtt cgccagcaat
    50161 gtgattgaaa atagctatgc tctttatgat gaagaacaaa tgtctccaga tattgaacga
    50221 gctgtttcat tcatagaaaa agaaggagtt acgaagttgt tgtctgttaa ggatgcaatg
    50281 gggatggtga ccaatcgttc tttgttgatt cttgtagacc attcaaagac agccttaaca
    50341 ttatcaaaag aattttatga tttatttacc caaaccattg ttattgacca ccatagaagg
    50401 gatcaggatt ttccagataa tgcggttatt acttatatcg aaagtggtgc aagtagtgcc
    50461 agtgagttgg taacggaatt gattcagttc cagaattcta agaaaaatcg tttgagtcgt
    50521 atgcaagcaa gtgtcttgat ggctggtatg atgttggata ctaaaaattt cacctcgcga
    50581 gtaactagtc ggacatttga tgttgctagc tatctcagaa cgcgcggaag tgatagtatt
    50641 gctatccagg aaatcgctgc gacagatttt gaagaatatc gtgaggtcaa tgaacttatt
    50701 ttacaggggc gtaaattagg ttcagatgta ctaatagcag aggctaagga cacgaaatgc
    50761 tatgatacag ttgttattag taaggcagca gatgccatgt tagccatgtc aggtattgaa
    50821 gcgagttttg ttcttgcgaa gaatacacaa ggatttatct ctatctcagc tcgaagtcgt
    50881 agtaaactga atgtacaacg gattatggaa gagttaggcg gtggaggcca ctttaatttg
    50941 gcagcagctc aaattaaaga tgtaaccttg tcagaagcag gtgaaaaact gacagaaatt
    51001 gtattaaatg aaataaagga aaaggagaaa gaagaatgaa agtaatcttt ttagcagatg
    51061 ttaaaggaaa aggtaaaaaa ggcgaaatta aggaagtacc aacagggtat gcgcaaaact
    51121 ttcttatcaa aaagaatcta gccaaagaag cgactgctca agctgtaggt gaacttcgtg
    51181 gtaaacaaaa atcggaagaa aaagctcacg ctgagatgat tgcagaaggg aaagcaatta
    51241 aagcacaact tgaagcagaa gaaactgttg tagaatttgt tgaaaaagtt ggtccagatg
    51301 gtcgtacctt tggttctatt accaataaga agattgcaga agaattacaa aagcaatttg
    51361 gaattaagat tgataaacgt catattcaag tacaagctcc gattcgagcg gttggtttga
    51421 ttgatgtgcc agtgaaaatc tatcaagata tcacaagtgt aatcaatctt cgtgtgaaag
    51481 aaggataagt ttacaccttc ttgacaagat tgtaaaagga agggaagtct gatggcagaa
    51541 gtagaagagt tacgagtaca acctcaagat atcttagctg agcaatccgt tttaggggct
    51601 atctttattg atgagagtaa acttgttttt gtgcgagaat acattgagtc tcgggacttt
    51661 tttaagtatg cccatcgttt gattttccaa gccatggtcg atttatccga tcgtggtgat
    51721 gccatagatg caacaacggt tcgtactatc cttgataatc aaggtgattt acagaatatt
    51781 ggtggcttgt cttacttggt tgagattgtc aattctgtgc caacttctgc taatgcggag
    51841 tattatgcta agattgttgc agaaaaagca atgctacgtc gtttaattgc caagttgaca
    51901 gagtctgtca accaagctta cgaagcgtca caaccagctg atgaaattat tgctcaggca
    51961 gaaaaagggt tgattgatgt cagtgaaaat gcaaatcgaa gcgggtttaa gaacattcga
    52021 gatgtgttga atctcaactt tggaaatctg gaagctcgct cgcaacaaac gaccgatatt
    52081 acaggtattg cgacaggtta tcgtgatttg gatcatatga caacaggact tcatgaggag
    52141 gagttgatta tcttagcagc tcgtccagca gttggtaaga cagcatttgc cttgaatatc
    52201 gctcagaaca ttgggactaa gttggacaaa acggttgcta ttttttcact cgaaatgggt
    52261 gcggaaagct tggtagatcg tatgttagct gcagaaggct tggtggagtc acattctatc
    52321 cgtacagggc aattgacaga tgaggagtgg caaaaatata ctattgctca gggtaatcta
    52381 gctaacgcca gtatctatat cgatgatacg ccaggtattc ggattacaga gattcgttct
    52441 cgttcccgta aattggctca agaaactgga aatcttggtt tgattttgat agactatttg
    52501 caacttatca cgggaactgg tcgagaaaat cgtcaacaag aagtttctga aatttctcgt
    52561 cagttgaaaa tactagccaa ggaattgaag gttccagtaa tcgctctgag tcagctttct
    52621 cgtggtgtag aacaacgtca ggacaagaga ccagtcttgt ctgatattcg tgaatctggg
    52681 tctattgagc aggacgctga tatcgtagct tttctctatc gcgatgacta ctatgaacgt
    52741 ggtggtgaag aagaggaggg tatcccaaat aataaggtgg aagttattat cgagaaaaac
    52801 cgtagtggag ctcgtggaac agtggaattg attttccaaa aagaatacaa taaattttca
    52861 agtatctcaa agagggaggc ataagatgtc agatgcattt acagatgtag ccaagatgaa
    52921 aaaaatcaaa gaagaaatca aggcacatga gggacaagtc gtagaaatga ctttggagaa
    52981 tggtcgtaag cgccaaaaaa atagattggg taagctaatt gaagtttatc catctctatt
    53041 tattgtggag tttggggatg tggaaggaga taaacaagtt aatgtttacg ttgaatcctt
    53101 tacttactca gatattctta cagaaaagaa tttgattcat tatcttgact aaagtgagaa
    53161 attttctcac tttttctttt ttctccgaat aatttaggtg aaggcaatca tcgctttata
    53221 ttatttttca aggaggaaga atgaaaattt taccgtttat agcaagagga acaagttatt
    53281 acttgaagat gtcagttaaa aagcttgttc cttttttagt agtaggattg atgctagcag
    53341 ctggtgatag tgtctatgcc tattccagag gaaatggatc gattgcgcgt ggggatgatt
    53401 atcctgctta ttataaaaat gggagccagg agattgatca gtggcgcatg tattctcgtc
    53461 agtgtacttc ttttgtagcc tttcgtttga gtaatgtcaa tggttttgaa attccggcag
    53521 cttatggaaa tgcgaatgaa tggggacatc gtgctcgtcg ggaaggttat cgtgtagaca
    53581 atacaccgac gattggttct attacttggt ctactgcagg aacttatggt catgttgcct
    53641 gggtgtcaaa tgtaatggga gatcagattg agattgagga atataactat ggttatacag
    53701 aatcctataa taaacgagtt ataaaagcaa acacgatgac aggatttatt cattttaaag
    53761 atttggatgg tggcagtgtt gggaatagtc aatcctcaac ttcaacaggc ggaactcatt
    53821 attttaagac caagtctgct attaaaactg aacccctagt tagtgcaact gtgattgatt
    53881 actattatcc tggagagaag gttcattatg atcagatact tgaaaaagac ggctacaagt
    53941 ggttgagtta tacggcttat aacggaagtc gtcgctatat acagctagag ggagtgactt
    54001 cttcacaaaa ttatcagaat caatcaggaa atatctctag ctatggatcc aataatagtt
    54061 caactgtcgg ttggaagaaa ataaatggta gttggtatca tttcaaatca aatggttcta
    54121 aatcaacagg atggctgaaa gacggttcta gctggtatta tttgaaatta tctggtgaaa
    54181 tgcagacagg atggttaaag gagaatggct cgtggtatta tctgggtagt tcaggggcaa
    54241 tgaaaacagg ctggtaccag gtctctggta agtggtatta ttcttactct tcaggcgcct
    54301 tagctgttaa tacgacggtg gatggctaca gagtaaacag tgatggagaa cgagtataga
    54361 aaattggagt aggagaaatt tcctgctctt ttctgtaagc agtttccttg acatttttct
    54421 tattttgcgc tatcatatat acatataata tatgggagtc tgtgtacagt ctgagaggaa
    54481 gtgttaaact tcgaccgcac ctgatctggg taatgccagc ggagggaacg atacttagtc
    54541 taattttgca ccttttccat gtatggtaaa ggtttttctt tttttttaaa aggaaaacga
    54601 gaagaggagg ttcttatgaa agcaagcatt gccttgcaag ttttacccct agcacagggg
    54661 attgatcgga tagctgttat tgatcaggtc attgcttatc tgcaaactca agaagtgacg
    54721 atggtagtga caccatttga aacggtcttg gaaggggagt ttgatgagct tatgcgcatt
    54781 ctaaaagaag cgctggaagt ggcagggcag gaggcagaca atgtctttgc caatgtcaaa
    54841 ataaatgtag gagagatttt aagtattgat gagaaacttg aaaagtatac tgagacgaca
    54901 cattagtcta ttgggctttc tcggagtatt gtcaatctgg cagttagcag gttttcttaa
    54961 acttctcccc aagtttatcc tgccgacacc tcttgaaatt ctccagccct ttgttcgtga
    55021 cagagaattt ctctggcacc atagctgggc gaccttgaga gtggctttac tggggctgat
    55081 tttgggagtt ttgattgcct gtcttatggc tgtgctcatg gatagtttga cttggctcaa
    55141 tgacctgatt taccctatga tggtggtcat tcagaccatt ccgaccattg ccatagctcc
    55201 tatcctggtc ttgtggctag gttatgggat tttgcccaag attgtcttga ttatcttaac
    55261 gacaaccttt cccatcatcg ttagtatttt ggacggtttt aggcattgtg acaaggatat
    55321 gctgaccttg tttagtctga tgcgggccaa gccttggcaa atcctgtggc attttaaaat
    55381 cccggttagc ctgccttact tttatgcagg tctgagggtc agtgtctcct acgcctttat
    55441 cacaactgtg gtatctgagt ggttgggagg ttttgaaggt cttggtgttt atatgattca
    55501 gtctaaaaaa ctgtttcagt atgataccat gtttgccatt attattctgg tgtcgattat
    55561 cagtcttttg ggtatgaagc tggtcgatat cagtgaaaaa tatgtgatta aatggaaacg
    55621 ttcgtagaat tagaatgttt ctgaaaaaga aaagaggaaa tcaaaatgaa gaaaacatgg
    55681 aaagtgtttt taacgcttgt aacagctctt gtagctgttg tgcttgtggc ctgtggtcaa
    55741 ggaactgctt ctaaagacaa caaagaggca gaacttaaga aggttgactt tatcctagac
    55801 tggacaccaa ataccaacca cacagggctt tatgttgcca aggaaaaagg ttatttcaaa
    55861 gaagctggag tggatgttga tttgaaattg ccaccagaag aaagttcttc tgacttggtt
    55921 atcaacggaa aggcaccatt tgcagtgtat ttccaagact acatggctaa gaaattggaa
    55981 aaaggagcag gaatcactgc cgttgcagct attgttgaac acaatacatc aggaatcatc
    56041 tctcgtaaat ctgataatgt aagcagtcca aaagacttgg ttggtaagaa atatgggaca
    56101 tggaatgacc caactgaact tgctatgttg aaaaccttgg tagaatctca aggtggagac
    56161 tttgagaagg ttgaaaaagt accaaataac gactcaaact caatcacacc gattgccaat
    56221 ggcgtctttg atactgcttg gatttactac ggttgggatg gtatccttgc taaatctcaa
    56281 ggtgtagatg ctaacttcat gtacttgaaa gactatgtca aggagtttga ctactattca
    56341 ccagttatca tcgcaaacaa cgactatctg aaagataaca aagaagaagc tcgcaaagtc
    56401 atccaagcca tcaaaaaagg ctaccaatat gccatggaac atccagaaga agctgcagat
    56461 attctcatca agaatgcacc tgaactcaag gaaaaacgtg actttgtcat cgaatctcaa
    56521 aaatacttgt caaaagaata cgcaagcgac aaggaaaaat ggggtcaatt tgacgcagct
    56581 cgctggaatg ctttctataa atgggataaa gaaaatggta tccttaaaga agacttgaca
    56641 gacaaaggct tcaccaacga atttgtgaaa taatgacaga aattagacta gagcacgtca
    56701 gttatgccta tggtcaggag aggattttag aggatatcaa cctacaggtg acttcaggcg
    56761 aagtggtttc catcctaggc ccaagtggtg ttggaaagac caccctcttt aatctaatcg
    56821 ctgggatttt agaagttcag tcagggagaa ttgtccttga tggtgaagaa aatcccaagg
    56881 ggcgcgtgag ttatatgttg caaaaggatc tgctcttgga gcacaagacg gtgcttggaa
    56941 atatcattct gcccctcttg attcaaaagg tggataaggc agaaactatt tcccgagcgg
    57001 ataaaattct tgcgaccttc cagctgacag ctgtaagaga caagtatcct catgaactta
    57061 gcggtgggat gcgccagcgt gtagccttac tccggaccta cctttttggg cataagctct
    57121 ttctcttaga tgaggccttt agcgccttgg atgagatgac aaagatggaa ctccacgctt
    57181 ggtatcttga gattcacaag cagttgcagc taacaaccct gatcatcacg catagtattg
    57241 aggaggccct caatctcagc gaccgcatct atatcttgaa aaatcgccct gggcagattg
    57301 tttcagaaat taaactagat tggtctgaag atgaggacaa ggaagtccaa aagattgcct
    57361 acaaacgtca aatcttggca gaattaggct tagataagta gaaaaatagg gagttggtga
    57421 agattatcct ttaccagcgc cctttttctt ttaaaaatga gaaaatttcg gtataatagt
    57481 caaacaaggt caaggtttaa agagagaggt gggtttgtta tgagatttaa aaatacatcg
    57541 gatcatattg aggcctacat caaggcgatt ttagatcaat ctggtatcgt ggagttgcaa
    57601 cggagtcagt tggcagatac ctttcaggtt gttcctagtc agattaacta cgtgatcaag
    57661 acacgcttta cggaaagtag aggctacttg gttgaaagta agcgtggtgg cggaggctac
    57721 attcgtatag gacggattga gttttctagt catcatgaaa tgctccggga gctgctttat
    57781 tcgattggtg agcgagtcag tcaagaaatt tatgaggata ttctccagct tttggttgag
    57841 caggaattga tgaccaagca ggagatgaat ttgctagtat cagtagcttt ggatcgcgtt
    57901 ttaggagaag aagctccagt tgttcgagca aacatgctac gtcaggtcat acaagaggta
    57961 gatagaaaag ggaagtaaga tgaactattc aaaagcattg aatgaatgta tcgaaagtgc
    58021 ctacatggtt gctggacatt ttggagctcg ttatctagag tcgtggcact tgttgattgc
    58081 catgtctaat cacagttata gtgtagcagg ggcaacttta aatgattatc cgtatgagat
    58141 ggaccgttta gaagaggtgg ctttggaact gactgaaacg gactatagcc aggatgaaac
    58201 ctttacggaa ttgccgttct ctcgtcgttt gcaggttctt tttgacgaag cagagtatgt
    58261 agcgtcagtg gtccatgcta aggtgctagg gacagagcac gtcctctatg cgattttgca
    58321 tgatggcaat gccttggcga ctcgtatctt ggagagggct ggtttttctt atgaagacaa
    58381 gaaagatcag gtcaagattg ctgctcttcg tcgaaattta gaagaacggg caggctggac
    58441 tcgtgaagat ctcaaggctt tacgccaacg ccatcgtaca gtagctgaca agcaaaattc
    58501 tatggccaat atgatgggca tgccgcagac tcctagtggt ggtctcgagg actatacgca
    58561 tgatttgaca gagcaagcgc gttctggcaa gttagaacca gtcatcggtc gggacaagga
    58621 aatctcacgt atgattcaaa tcttgagccg gaagactaag aacaaccctg tcttggttgg
    58681 ggatgctggt gtcgggaaaa cagctctggc gcttggtctt gctcagcgta ttgctagtgg
    58741 tgacgtgtct gcggaaatgg ctaagatgcg cgtgttagaa cttgatttga tgaatgtcgt
    58801 tgcagggaca cgcttccgtg gtgactttga agaacgcatg aataatatca tcaaggatat
    58861 tgaagaagat ggccaagtca tcctctttat cgatgaactc cacaccatca tgggttctgg
    58921 tagcgggatt gattcgactc tggatgcggc caatatcttg aaaccagcct tggcgcgtgg
    58981 aactttgaga acggttggtg ccaccactca ggaagaatat caaaaacata tcgaaaaaga
    59041 tgcggctctt tctcgtcgtt tcgctaaagt gacgattgaa gaaccaagtg tggcagatag
    59101 tatgactatt ttacaaggtt tgaaggcgac ttatgagaaa catcaccgtg tacaaatcac
    59161 agatgaagcg gttgaaacag cggttaagat ggctcatcgt tatttaacca gtcgtcactt
    59221 gccagactct gctatcgacc tcttggacga agcagcagca acagtgcaaa ataaggcaaa
    59281 gtatgtaaaa gcagacgatt cagatttgag tccagctgac aaggccctga tggatggcaa
    59341 gtggaaacag gcagcccagc taatcgcaaa agaagaggaa gtacctgtct acaaagactt
    59401 ggtgacagag tctgatattt tgaccacctt gagtcgcttg tcaggaatcc cagttcaaaa
    59461 actgactcag actgacgcta agaaatatct aaatcttgaa gcagaactcc ataaacgggt
    59521 tatcggtcaa gatcaagctg tttcaagtat tagtcgtgcg attcgccgta atcagtcagg
    59581 aattcgcagt cacaagcgtc cgatcggttc ctttatgttc ctaggaccca caggtgtcgg
    59641 taagaccgag ttggccaagg ctttggcaga agttctcttt gatgacgaat catcccttat
    59701 ccgctttgat atgagtgagt atatggagaa attcgcagcc agccgtctaa atggagctcc
    59761 tccaggctat gtgggttacg aagaaggtgg ggagttgaca gagaaggttc gcaataaacc
    59821 ctattccgtt ctcctctttg atgaggtaga gaaggctcac ccagatatct ttaatgttct
    59881 cttgcaggtt ctggatgacg gtgtcttgac agatagcaag ggacgcaagg tcgatttttc
    59941 aaataccatt atcattatga catcgaacct aggtgcgact gcccttcgtg atgataagac
    60001 tgttggtttt ggggctaagg atattcgttt tgaccaggaa aatatggaaa aacgcatgtt
    60061 tgaagaactg aaaaaagctt atagaccgga attcatcaac cgtattgatg agaaggtggt
    60121 cttccatagc ctatctagtg accatatgca ggaagtggtg aagattatgg tcaagccttt
    60181 agtggcaagt ttggctgaaa aaggcattga cttgaaatta caagcttcag ctctgaaatt
    60241 gttagcaaat caaggatatg acccagagat gggagctcgc ccacttcgca gaaccctgca
    60301 aacagaagtg gaggacaagt tggcagaact tcttctcaag ggagatttag tggcaggcag
    60361 cacacttaag attggtgtca aagcaggcca gttaaaattt gatattgcat aaaagaataa
    60421 aagtaccagc atctgaccat aagtcacagt ggagtgaaac tcaatgaaaa tcaaagagca
    60481 aactaggcag ctagccgcag gttgctcaaa acactggttt gaggttgcag atagagctga
    60541 cgtggtttga agagattttc gaagagtata agctgcaaga tgaatgattt tcttgtattg
    60601 acgttgttgt tgacaaaaag tagcggataa atgaaatcca ttccattatc atagatgata
    60661 ggctggtagg aaattttcaa atagcataca ggaaatagat gtatggagtt ctggtagtag
    60721 aaagggagag agatgaacat tttagttgca gatgacgagg aaatgattag agaaggaatt
    60781 gcagcatttc tgacagaaga gggttatcat gtcattatgg ctaaggatgg acaagaggtc
    60841 ttggaaaaat ttcaagatct ccctatccat ctcatggtac tggatttaat gatgcctagg
    60901 aagagtggtt ttgaagtgtt aaaagaaatc aatcaaaagc acgatattcc tgtcatcgtc
    60961 ttgagtgctc tgggagatga aactactcag tcacaggtat ttgatctcta tgctgatgat
    61021 catgtgacaa aacctttttc tttggtactg cttgtcaagc gtattaaggc gcttatcaga
    61081 cgttactacg tcatagagga tctttggcga tatcaggatg taacagtgga ttttacctct
    61141 tacaaagcac attataaaaa tgaagaaatt gatctcaaac caaaggaatt actggtacta
    61201 aagtgtttga ttcagcataa aaatcaagtt ttaagtagag agcagatatt ggaagaaatt
    61261 tcaaaagatg tagctgattt accttgtgat agggtcgttg atgtctatat tcgtactctt
    61321 cgcaaaaaat tagctttaga ttgtatcgtg actgtgaaaa atgttgggta taagattagc
    61381 ttatgataaa aaatcctaaa ttattaacca agtctttttt aagaagtttt gcaattctag
    61441 gtggtgttgg tctagtcatt catatagcta tttatttgac ctttcctttt tattatattc
    61501 aactggaggg ggaaaagttt aatgagagcg caagagtgtt tacggagtat ttaaagacta
    61561 agacatctga tgaaattcca agcttactcc agtcttattc aaagtccttg accatatctg
    61621 ctcaccttaa aagagatatt gtagataagc ggctccctct tgtgcatgac ttggatatta
    61681 aagatggaaa gctattaaat tatatcgtga tgttagatat gtctgttagt acagcagatg
    61741 gtaaacaggt aaccgtgcaa tttgttcacg gggtggatgt ctacaaagaa gcaaagaata
    61801 ttttgctttt gtatctccca tatacatttt tggttacaat tgctttttcc tttgtttttt
    61861 cttattttta tactaaacgc ttgctcaatc ctctttttta catttcagaa gtgactagta
    61921 aaatgcaaga tttggatgac aatattcgtt ttgatgaaag taggaaagat gaagttggtg
    61981 aagttggaaa acagattaat ggtatgtatg agcacttgtt gaaggttatt catgagttgg
    62041 aaagtcgtaa tgagcaaatt gtaaaattgc aaaatcaaaa ggtttccttt gtccgtggag
    62101 catcacatga gttgaaaacc cctttagcca gtcttagaat tatcctagag aatatgcagc
    62161 ataatattgg agattacaaa gatcatccaa aatatattgc aaagagtata aataagattg
    62221 accagatgag ccacttatta gaagaagtac tggagtcttc taaattccaa gagtggacag
    62281 agtgtcgtga gaccttgact gttaagccag ttttagtaga tattttatca cgttatcaag
    62341 aattagctca ttcaataggt gttacaattg aaaatcaatt gacagatgct accagggtcg
    62401 tcatgagtct tagggcattg gataaggttt tgacaaacct gattagtaat gcaattaaat
    62461 attcagataa aaatgggcgc gtaatcatat ccgagcaaga tggctatctc tctatcaaaa
    62521 atacatgtgc gcctctaagt gaccaagaac tagaacattt atttgatata ttctatcatt
    62581 ctcaaatcgt gacagataag gatgaaagtt ccggtttggg tctttacatt gtgaataata
    62641 ttttagaaag ctatcaaatg gattatagtt ttctccctta tgaacacggt atggaattta
    62701 agattagctt gtagacagat tagtttttta ttaaagttca tatagggtta acataagtgt
    62761 gttattcttt gtgtagataa aagaaaggat actaatatgg tattagcgat tattttagta
    62821 acattcttta ttcgattgat ttttttaaag cgttcgatag agaatgagaa acgaatcctt
    62881 agcaatggcg ggaaagaatt tggagttgag aatacaaaac gattaactat ggctcatatt
    62941 gttttttatc tctcttgctt ggttgaggca atggtgcaca agacaatttt tgatggcatg
    63001 ggcatggttg gtttagtctt gcttattttt tctatgctga tgttaatgtt ggtgattcac
    63061 ttgttgggag atatttggac agtgaagctt atgcttgtca ataatcacaa atatgtagat
    63121 catatcttgt ttaggacagt aaaacatcct aattactttt taaatattct tcctgagttg
    63181 attggcttga ccttgttgag tcatgcttat gtgacttttg ttttagtttt tccagtttat
    63241 gcagttattt tgtatcgacg aatagctgaa gaggaaaagc tattacatga agttataatc
    63301 ccaaatggaa gcataaagag ataaatacaa aattcgattt atatacagtt catattgaag
    63361 taatatagta atagacttca tgcgaaacaa aatatggtac aatagttcta tgaattatga
    63421 agcaaggttg agaatatttt tgccaaagta aaaacgttta aaatgttttc aacaacctat
    63481 cgaaatcatc gtaaacgctt cggattacga atgaatttga ttgctggcat tatcaatcat
    63541 gaactaggat tctagttttg caggaagtct aatgttaaga aaaatattgg agaaaataaa
    63601 catgtttgca tcaaaaagcg aaaaaaaagt acattattca attcgtaaat ttagtattgg
    63661 agtagctagt gtagctgttg ccagtctttt tatgggaagt gtggttcatg cagaaggggt
    63721 tagaagtggg gataccccta aggttacatc tagtggggat gaagtcgagt cgcatctaaa
    63781 aaaaatattg agtgagatcc aaacacaatt agatagaaaa cgacatgcca aaactgtagc
    63841 gctaattaac aagttgcaag acattaagag aacgtattcg tataaattaa atgttttaga
    63901 agagaagccg aaagctgagt tgacgtcaaa aacaaaagaa gagttaaccg cagcttttga
    63961 gcagtttaaa aaagatacat taccaacaga accaggaaaa aaggtagcag aagctaagaa
    64021 gaaggttgaa gaagctaaga aaaaagccaa ggctcaaaaa gaagaagatt accgtaacta
    64081 cccaaccatt acttatgtga aagttaaaga agcggagctt gaactagtaa aagaggaagc
    64141 taaggaatct caaaacgagg aaaaaattaa gcaagcaaaa gcgaaagttg agagtaaaaa
    64201 agctgaggct acaaggttag aaaaaatcaa gacagatcgt aaaaaagcag aagaagaagc
    64261 taaacgaaaa gcagcagaag aagataaagt taaagaaaaa ccagctgaac aaccacaacc
    64321 agcgccggct cc
//
LOCUS       DAVKAU010000006        59852 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVKAU010000006 DAVKAU010000000
VERSION     DAVKAU010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.006"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..261)
                     /locus_tag="VWX48_000430"
     CDS             complement(<1..261)
                     /locus_tag="VWX48_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9171116.1"
                     /translation="MQDNYTTKGKHLTIDSRSLIERWKKEGKSNREIASLLGKAPQTI
                     HTKIKRRTVRKCLGKGRFKEVYSADYAQQSYENNRKHSVKRSS"
     gene            complement(706..1104)
                     /locus_tag="VWX48_000431"
     CDS             complement(706..1104)
                     /locus_tag="VWX48_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171117.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(1432..1914)
                     /gene="greA"
                     /locus_tag="VWX48_000432"
     CDS             complement(1432..1914)
                     /gene="greA"
                     /locus_tag="VWX48_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU9171118.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(1985..3640)
                     /gene="mltG"
                     /locus_tag="VWX48_000433"
     CDS             complement(1985..3640)
                     /gene="mltG"
                     /locus_tag="VWX48_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU9171119.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLLAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLIKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(3721..4215)
                     /locus_tag="VWX48_000434"
     CDS             complement(3721..4215)
                     /locus_tag="VWX48_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171120.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(4212..4676)
                     /locus_tag="VWX48_000435"
     CDS             complement(4212..4676)
                     /locus_tag="VWX48_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171121.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEETLLYVTSQGYSMIWFNPFYLEEQ"
     gene            complement(4686..6020)
                     /locus_tag="VWX48_000436"
     CDS             complement(4686..6020)
                     /locus_tag="VWX48_000436"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU9171122.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(6031..6648)
                     /locus_tag="VWX48_000437"
     CDS             complement(6031..6648)
                     /locus_tag="VWX48_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9171123.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(6696..9800)
                     /locus_tag="VWX48_000438"
     CDS             complement(6696..9800)
                     /locus_tag="VWX48_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9171124.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINRQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADTNLFAFTVTEYLDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDVDLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQKLGQFELKDGTLQARKSLAYSLAHLFEGRDRDRVSFSQEFQNLAQ
                     DLTHPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFL
                     TSQVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADSHQIYVT
                     SYATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENH
                     LGELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVY
                     KNELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMED
                     YQGASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPA
                     KERQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHR
                     MGQEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGIS
                     EAST"
     gene            complement(9893..11059)
                     /locus_tag="VWX48_000439"
     CDS             complement(9893..11059)
                     /locus_tag="VWX48_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9171125.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHSRINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(11067..12161)
                     /locus_tag="VWX48_000440"
     CDS             complement(11067..12161)
                     /locus_tag="VWX48_000440"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9171126.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(12319..14001)
                     /locus_tag="VWX48_000441"
     CDS             complement(12319..14001)
                     /locus_tag="VWX48_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171127.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSSSKGSSVALENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENR
                     PVLKDITCSIFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKE
                     WRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDT
                     EVGERGRLLSGGRSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEK
                     TVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(14173..16131)
                     /locus_tag="VWX48_000442"
     CDS             complement(14173..16131)
                     /locus_tag="VWX48_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9171128.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(16335..17957)
                     /locus_tag="VWX48_000443"
     CDS             complement(16335..17957)
                     /locus_tag="VWX48_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9171129.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTTKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            18063..19508
                     /locus_tag="VWX48_000444"
     CDS             18063..19508
                     /locus_tag="VWX48_000444"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU9171130.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLCLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(19554..19748)
                     /locus_tag="VWX48_000445"
     CDS             complement(19554..19748)
                     /locus_tag="VWX48_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9171131.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(19849..20457)
                     /locus_tag="VWX48_000446"
     CDS             complement(19849..20457)
                     /locus_tag="VWX48_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU9171132.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDHL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            complement(20482..20994)
                     /locus_tag="VWX48_000447"
     CDS             complement(20482..20994)
                     /locus_tag="VWX48_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU9171133.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(21080..22015)
                     /locus_tag="VWX48_000448"
     CDS             complement(21080..22015)
                     /locus_tag="VWX48_000448"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU9171134.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(22086..22385)
                     /locus_tag="VWX48_000449"
     CDS             complement(22086..22385)
                     /locus_tag="VWX48_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU9171135.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(22375..23124)
                     /locus_tag="VWX48_000450"
     CDS             complement(22375..23124)
                     /locus_tag="VWX48_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU9171136.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(23178..23537)
                     /locus_tag="VWX48_000451"
     CDS             complement(23178..23537)
                     /locus_tag="VWX48_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU9171137.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKTK"
     gene            complement(23539..24939)
                     /locus_tag="VWX48_000452"
     CDS             complement(23539..24939)
                     /locus_tag="VWX48_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU9171138.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(25234..25473)
                     /locus_tag="VWX48_000453"
     CDS             complement(25234..25473)
                     /locus_tag="VWX48_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU9171139.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(25505..25975)
                     /gene="ssbA"
                     /locus_tag="VWX48_000454"
     CDS             complement(25505..25975)
                     /gene="ssbA"
                     /locus_tag="VWX48_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU9171140.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(25987..26277)
                     /locus_tag="VWX48_000455"
     CDS             complement(25987..26277)
                     /locus_tag="VWX48_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU9171141.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(26430..27776)
                     /gene="asnS"
                     /locus_tag="VWX48_000456"
     CDS             complement(26430..27776)
                     /gene="asnS"
                     /locus_tag="VWX48_000456"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU9171142.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGMPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(27792..28157)
                     /locus_tag="VWX48_000457"
     CDS             complement(27792..28157)
                     /locus_tag="VWX48_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9171143.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEGVQPCYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(28150..29337)
                     /locus_tag="VWX48_000458"
     CDS             complement(28150..29337)
                     /locus_tag="VWX48_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9171144.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(29334..29822)
                     /locus_tag="VWX48_000459"
     CDS             complement(29334..29822)
                     /locus_tag="VWX48_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU9171145.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            30143..30691
                     /locus_tag="VWX48_000460"
     CDS             30143..30691
                     /locus_tag="VWX48_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9171146.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(30969..31697)
                     /gene="yaaA"
                     /locus_tag="VWX48_000461"
     CDS             complement(30969..31697)
                     /gene="yaaA"
                     /locus_tag="VWX48_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU9171147.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKALKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(31776..31940)
                     /locus_tag="VWX48_000462"
     CDS             complement(31776..31940)
                     /locus_tag="VWX48_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU9171148.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(32119..33714)
                     /locus_tag="VWX48_000463"
     CDS             complement(32119..33714)
                     /locus_tag="VWX48_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171149.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFSKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(33726..34136)
                     /locus_tag="VWX48_000464"
     CDS             complement(33726..34136)
                     /locus_tag="VWX48_000464"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9171150.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(34252..35043)
                     /gene="yghU"
                     /locus_tag="VWX48_000465"
     CDS             complement(34252..35043)
                     /gene="yghU"
                     /locus_tag="VWX48_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU9171151.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(35056..37752)
                     /locus_tag="VWX48_000466"
     CDS             complement(35056..37752)
                     /locus_tag="VWX48_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU9171152.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38056..39240
                     /gene="mntE"
                     /locus_tag="VWX48_000467"
     CDS             38056..39240
                     /gene="mntE"
                     /locus_tag="VWX48_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU9171153.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(39383..41254)
                     /locus_tag="VWX48_000468"
     CDS             complement(39383..41254)
                     /locus_tag="VWX48_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9171154.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDNQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(41251..42435)
                     /locus_tag="VWX48_000469"
     CDS             complement(41251..42435)
                     /locus_tag="VWX48_000469"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU9171155.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALESETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(42447..43214)
                     /locus_tag="VWX48_000470"
     CDS             complement(42447..43214)
                     /locus_tag="VWX48_000470"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU9171156.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTAPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(43491..44339)
                     /locus_tag="VWX48_000471"
     CDS             complement(43491..44339)
                     /locus_tag="VWX48_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9171157.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGMIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGSGSIAL
                     GYIPVI"
     gene            complement(44341..44715)
                     /locus_tag="VWX48_000472"
     CDS             complement(44341..44715)
                     /locus_tag="VWX48_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU9171158.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(44789..46141)
                     /locus_tag="VWX48_000473"
     CDS             complement(44789..46141)
                     /locus_tag="VWX48_000473"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU9171159.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEALKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(46165..46944)
                     /locus_tag="VWX48_000474"
     CDS             complement(46165..46944)
                     /locus_tag="VWX48_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU9171160.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(46931..47788)
                     /locus_tag="VWX48_000475"
     CDS             complement(46931..47788)
                     /locus_tag="VWX48_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU9171161.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERW
                     LGGWKHEKK"
     gene            47924..48892
                     /locus_tag="VWX48_000476"
     CDS             47924..48892
                     /locus_tag="VWX48_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9171162.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(48926..49837)
                     /gene="whiA"
                     /locus_tag="VWX48_000477"
     CDS             complement(48926..49837)
                     /gene="whiA"
                     /locus_tag="VWX48_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU9171163.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(49834..50811)
                     /locus_tag="VWX48_000478"
     CDS             complement(49834..50811)
                     /locus_tag="VWX48_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU9171164.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGIEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(50808..51698)
                     /gene="rapZ"
                     /locus_tag="VWX48_000479"
     CDS             complement(50808..51698)
                     /gene="rapZ"
                     /locus_tag="VWX48_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU9171165.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLLELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(51750..52130)
                     /locus_tag="VWX48_000480"
     CDS             complement(51750..52130)
                     /locus_tag="VWX48_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU9171166.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(52141..52728)
                     /locus_tag="VWX48_000481"
     CDS             complement(52141..52728)
                     /locus_tag="VWX48_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU9171167.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(52737..53969)
                     /gene="clpX"
                     /locus_tag="VWX48_000482"
     CDS             complement(52737..53969)
                     /gene="clpX"
                     /locus_tag="VWX48_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU9171168.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(54171..54677)
                     /locus_tag="VWX48_000483"
     CDS             complement(54171..54677)
                     /locus_tag="VWX48_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU9171169.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(54807..55325)
                     /locus_tag="VWX48_000484"
     CDS             complement(54807..55325)
                     /locus_tag="VWX48_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU9171170.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            complement(55821..57143)
                     /locus_tag="VWX48_000485"
                     /pseudo
     CDS             complement(55821..57143)
                     /locus_tag="VWX48_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-beta-N-acetylmuramidase"
     gene            complement(57181..57939)
                     /locus_tag="VWX48_000486"
     CDS             complement(57181..57939)
                     /locus_tag="VWX48_000486"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU9171171.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNFKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(58036..58713)
                     /locus_tag="VWX48_000487"
     CDS             complement(58036..58713)
                     /locus_tag="VWX48_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU9171172.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            complement(58722..59666)
                     /locus_tag="VWX48_000488"
     CDS             complement(58722..59666)
                     /locus_tag="VWX48_000488"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU9171173.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWIKIEDDASAYGYL"
BASE COUNT        17228 a        13626 c        11224 g        17774 t
ORIGIN      
        1 gcttgatctc ttgaccgagt gcttgcgatt attttcataa gactgttgag catagtcggc
       61 agaataaacc tctttgaagc gcccttttcc aagacatttt cggactgtcc tacgcttgat
      121 tttagtgtgg atagtttgag gagcttttcc aagtagagag gcaatttctc tatttgattt
      181 tccttctttt ttccatcttt cgattaagct acggctatcg attgtcaaat gtttaccttt
      241 tgtagtataa ttgtcttgca tttctgtgcc tttcttgtgt ttgtggttga acaacaagta
      301 taacacagag gtgttttctt atgcctacaa gagctttcat tatttccatt ttcttttgga
      361 tttcactcta ttctgaaaaa cttgtgtata tttactgaag ctagcaagtc ttacctgtaa
      421 atttaatgaa agcaacacaa aatccgagag gggaatctcg gattaataga tagagagttt
      481 ttagtttaaa taaattgttt aaaatatcaa caacatcact tcttttctta acctgataag
      541 tcttgattcc taattttggg gctacgatta tattgtcctc aatatcgtct agaaagacac
      601 aatttctagg ttataactgg tatttatcga tagttactca tatacatcag tccacctcca
      661 tacttatgtg cgagcctctc tttgtattat acctccatac tcaccttaca gattcttttg
      721 gtaataatat ctttgcctaa tgtagagata gtcttgcaaa gaaaaaactt ccttgtagcc
      781 atgtttctga taaaagtccg gtgcctggaa ctggtaagta ttgacaaagg caaaacaaca
      841 atttcgattc ttagcttcac tttctgcctg ttgcaatagt tttgaaccga ttccttgtcc
      901 tcgcagttcc tcttttacaa acaaatactc gatttctagc caatttccaa aagtctctgc
      961 tatcaaacct gccaggagat tgcccttttc atcttcgaca taaagattaa gtggctcact
     1021 ttcagcctct tctctttttg aacggttata aacacgaatc agattcccta tttcttgcga
     1081 tttatgtgat tccttatttt ccaatctaaa gtatagtgaa atgaaataaa acatgcgcaa
     1141 atcgattaag gaatttaatc taatttctaa caatgtctta gaaatcaaag tgtactattt
     1201 taacttcaat gcactataca tctaatactc aataaaaatc aaagagcaaa ctaggaaact
     1261 agccgcaggt tgctcaaaac actgttttga ggttgtagat gaaactgacg aagtcagtaa
     1321 ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag agtagcaaaa
     1381 tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt tttaggctgt
     1441 tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa tggttgctgt
     1501 atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg aaaccttacc
     1561 tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt cgtcctcacc
     1621 aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa ctgcgtcgct
     1681 attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc cttcgacaaa
     1741 ggcttgttca tccttagctg cttcgtactc actgttttct gaaaggtcac cgtatgaacg
     1801 ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt cttctaattc
     1861 tttttcaagt ttttcctttt cctcaagggt cataggatat gttttttctg ccatttttct
     1921 caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca taattttagt
     1981 ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg tcttcttgat
     2041 tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg ttatcgctct
     2101 tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact ggaccaggca
     2161 tgagacctac atttttataa acattataag gtgaatcaat gttggtatca atcgcaacat
     2221 cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt gcaatattac
     2281 tttgaagtgg catatcacga ttcaaacgat tgtagaatac acctgcaatg agcttacgat
     2341 cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac tcattgacag
     2401 tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc atagcagcta
     2461 acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat gtagctggga
     2521 aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa ctttccagta
     2581 aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact ttagccaaga
     2641 aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca gtttgagcaa
     2701 tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt tcttgcggtt
     2761 catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata ctcttttgca
     2821 aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa aaactaaaaa
     2881 tcagaccatg ctttatcaaa ccagcttttt caagcgtcgt accgatttct tgaacgtttg
     2941 aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata ggtaataagg
     3001 aatctagcac gtactggtaa ccaaagtaac cacctgctaa gagcaaggca aggaatacaa
     3061 ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggc ttaacgggtt
     3121 ttgctccttc tctacggcta cgacgtgatg tatctctgat gatatccact gtttctgtag
     3181 caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc gtataggaaa
     3241 cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt ctaacaggac
     3301 ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct tgacttggat
     3361 gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct ggtacacctt
     3421 gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc gttgacaagg
     3481 aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact actgcctcat
     3541 cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga atctgctctt
     3601 taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc tccttgttga
     3661 taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac ttttcctaac
     3721 ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg ttgactggga
     3781 ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt catgacaggt
     3841 tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg tcagcaattt
     3901 ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca cagagatata
     3961 accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt cttgcagatg
     4021 gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt tttcagcaac
     4081 cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag gaatggcttc
     4141 ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt ctaatcttgc
     4201 ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat actatagccc
     4261 tggctagtta catagagcaa agtttcttct tcatcaacaa aaccgttcat ttcaaaatag
     4321 gaaagcagct catcaggact ctccaaacga atccctttgt aatccagctc aactgccacc
     4381 tctttcaagg ctgcaagaag aagtgttccc aggccctgtc tctgatggtc agactcgatg
     4441 actaaagaat gtacttttag acattgcgga ttgtctgact ggggacttga taaaatatag
     4501 cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt acggatactt
     4561 tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt ctgaagtgcc
     4621 cctatctcag gcaaatcaaa cttgcttgcc tgaatgatct taattggaat ttccatggga
     4681 acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga gtattcatag
     4741 gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc taggagtgga
     4801 gaaacatttt caacagtaat cacttggtgt tttttgttga ttttattggc taggtcttct
     4861 accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc tagataaaca
     4921 gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca gggcaatggt tcttgtaaag
     4981 gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg agccgcatcc
     5041 aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat caataatcac tgtatcattg
     5101 acaattttct cagtgaaacg acgtttaaca ccggcaaatg ttttcaagtg ctcacgcacc
     5161 aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc attcatgata
     5221 ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg gaaatgaacg
     5281 gtgaaggttg aaccagttgt tgaacgaaga agatcactag ctacaaagtc attgccttca
     5341 gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa ttcagcatct
     5401 tcaccataga caaaaagacc cttggtaatt tgtttggcat agtcgttaaa ggcattgaaa
     5461 acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt gataatagag
     5521 tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa gacaaaatat
     5581 ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt atctgtaatg
     5641 tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc tcctgctact
     5701 cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg tttgtagctg
     5761 ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa ggcatttcca
     5821 gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat ggtaattcct
     5881 gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc ctgaaccttg
     5941 tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt aattccgata
     6001 aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca gattcaactc
     6061 ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga tttggctctt
     6121 ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt cattcttggt
     6181 agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt tttggctata
     6241 tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat tgccctgtct
     6301 aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta ggtagttagc
     6361 agagcgtttc tttttcaagt ccgcacgcgc ttcttcacgc gccacctccg catagctctt
     6421 tccttctttt ttaaccccta aaggagcctt tttaggtttt tcgacttgct tttcaatcgg
     6481 ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat ctcgatactc
     6541 acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg gcatttcagt
     6601 caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt tctatttcct
     6661 ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc agaaattccc
     6721 aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc gtccaatact
     6781 tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc aatggttccc
     6841 ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg ggcacggcca
     6901 atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac tgtatctgca
     6961 cctgtcaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc atctctttct
     7021 ccttggttaa aggccttggt catgtcttgt ctttccttgg ctggggttga acccgtaatt
     7081 ttaaaggaag tcaggcccaa gtctggcagt tcttgttcaa ttttttccaa cattcccttg
     7141 aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag taggtctcgg
     7201 agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc aggagtgtca
     7261 catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg ctgaaattcc
     7321 tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag gtaaatagcc
     7381 ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg caattcagtc
     7441 agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc cactcgctct
     7501 gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac gatttggaaa
     7561 atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc aaagaccgac
     7621 ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt catgacctga
     7681 gcttcatcta agaaaaggaa gtcaaaggcc atcccctgat aaagctcact gtcctgacgg
     7741 aaggtggcat agctagtcac atagatttga tggctatcgg caagaatctc ctcacgactt
     7801 gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg aaactcatcc
     7861 gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc ttttgtcact
     7921 tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc atcagccaaa
     7981 atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt ttcctgataa
     8041 tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg atgcgtcaaa
     8101 tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcggtc tcgcccttca
     8161 aagagatgag ctaaactgta ggccaaggat ttccgagcct gcaaggtccc atcttttaat
     8221 tcaaattgcc ccagtttctg taaattttgg cgaattttct tggtttcttc atcgaaaaag
     8281 taaacttgat tagacgaatc aatataaaaa tcctgattgg caaccaaggc ctgcatggct
     8341 tggtcgattt cctcctgggc aatatcttga aaatcaaact ggatttccaa gagacctccc
     8401 ttggaggcaa tctgcacctg aggactcgct aggctataaa gctcttctag tttatctgat
     8461 aggtcaacat gcccgagttt ttcaaagact ggaatgatat catgaaaaaa atgatagaca
     8521 gactctgctt ttaaggcctg acgccaagat tgaaaatcgg cttcaaagcc cgcagccaaa
     8581 cagacttgga aaattctttc ttctaagtcc acgtcacttg aaaatggtaa ttcttctagc
     8641 tcttgtcggc tagatacctg tctatttcca taatcaaact gaatttctaa acgaatccga
     8701 ttatcttctt ccctgtcaaa gtaaaaagag ggcgcaaaag ttttgatttg tagacgttct
     8761 ggagctgaaa cggtgcccat ctggataaaa agagtcagac aggaggccaa tttgtctcga
     8821 tcactgctat caaattgcag gtatttcttt ccttgttgac ccacaggtaa cactttaatt
     8881 tccttgagaa gacgcatctg ctggtctgtt aaaaaataaa cctgaccttt atggaaaagt
     8941 actgctccct gataaaagac attgacccta ggactctcac tgatttccat ttcaaaatag
     9001 tccaagtatt ctgttactgt aaaggcaaat agattggtat cagcatgcat atcctgaaaa
     9061 agcagggttt ggtagctatc cacttgatgg tcaaattgaa aatggggcaa ggccatcagt
     9121 aaattcacac cctgctcaaa aaaggtcaga gggaaaaaga ggtgccgacc ttggttttgg
     9181 aaaaagaggt ctggaaccag cccttcctcc gttagtccgt gcaagaaagt caaaagttct
     9241 tggctggcat catcaaaggc ttcccaagaa agagactcct cataaatctt gccaatcata
     9301 tacgactttc tctgctcgac aatccttaaa aaaagtggaa tatcccgaat gacatagtat
     9361 ttttgtctat tgatttggcc gattctcaga gtccacaaga tatgattggt tcctgcttcc
     9421 acctgaccca cagctgataa ctcataggcg cattctgatt tcggagataa aattcgattc
     9481 aaaaacttgc cacccaaggt caccttggtt tcaacggcct ctttttcttc atgaccttct
     9541 tccagactcc acaagatttc ctgaccacgc tcatcatttt tcagaaaatg ctctagcgct
     9601 gccaaatgca cacagtagcc cctcttttga aaagaatcac aggcacaaaa aaccaaatca
     9661 tcctctaaac tatagcgcag ttcttcttct gcaacgcgag cgtagagccg attgttcttt
     9721 tccttgatga tatcaacctt accagtttca taaagggcaa caccttcgat acgaactttc
     9781 cccggaatca atttagccat attttcacct ttaccttatc tgtttattat accatatttt
     9841 cgcctatgaa aatagccttc taggaagact tttctcctag aaggctggat ttttaacgtt
     9901 tggcaaaagt agccacaatc cgctgacaga cttcttgcaa cagagatttg ggcatagcta
     9961 tattgatgcg ggaatggaga cttccttcct ctccaaaatc caaaccacgg ttgaggataa
    10021 ccttggcttc atttctcaac aactcttgca atgtttcatc agtcaggtca taggctgaaa
    10081 agtcaagcca aatcaagtag gtaccttgcg gtttcatgac cttgatttta gtctcttttc
    10141 caaatagatc caccacataa ttgatgtggt cttcaaagac ttgcttgagt tcctctagcc
    10201 aatctttacc gtatctatag gcagcttctg tcgccaaata acccaagcct gaaatttcat
    10261 gctgattatt ggccaacagg cgtttctgga aagctagtct caacttagga ttttcaatga
    10321 ctgcatagga attttttgtt ccagcaatat taaatgtttt agtggcactg ctcaagacga
    10381 tagcaaaatt tttgaaggca ggattgatgg tattgaaaga ctggtgtttg tgaccaaaga
    10441 gggtcaaatc ttggtgaatc tcatccgaaa ctaacaaaac accgtgtttt tggcagagtt
    10501 ggccaatctt ctccaacact tctttttccc aaacacgtcc accaggattg tgagggttgc
    10561 aaagaatata gagtttaacc tcctcttcca ccaaatcctt ttcaagttgg tcaaagtcaa
    10621 tctcaaacag actatccttt tccactaagg aattagtaat caatctacga ttattcaact
    10681 tgacactgcg agcaaagggt gggtagacag gcgtgttaat taaaaccgcc tcgccttctt
    10741 ttgtaaaggt ttgaatagct gttgagatgg ctggtaccac accctcgata aagacaagag
    10801 cctctttgtc aaagttgtaa ccgtattgtg tagcttccca cttttgaact tccttaatta
    10861 agtcttcact ggcataggta taaccataaa ccagttggtc tgcgtaagtt tgcacggctt
    10921 ggtggatttc aggcaagact acaaagtcca tatccgctat ccaagctggt agaacttcac
    10981 tatccgtttc tgtttctttc catttatagg tatggtgccc taaacggttg ggcaggcttg
    11041 taaaatcata ttttcccatc tttgtcttat ccttctaagg cttggcgcaa atctgcaatc
    11101 aaatctctag catcctcaat cccaatagac aaacgcaaga ggtcatctgt caaaccataa
    11161 gaatggcgta cttctgctgg aatatcagca tgagtttgag tcgttggata agtaataaga
    11221 ctttccactc cacccaaact ttccgcaaaa gagaagacct tgagactgtt caaaatatga
    11281 ggaatgcgtg tttcatcggc tactttaaag gaaatcatgc ctccacgacc agtgtagaga
    11341 acttccttaa ctgctggaga atccttcaaa aaggcaacca cttcttgggc gttagctgtt
    11401 gagcgctcca tacgaagaga caaggtcttg agaccacgaa gcaactggta gctgtcaaat
    11461 ggagacaaga ctgcccctgt tgtattaaga ttgtaaaaaa gcttctcgta tagttctaaa
    11521 ctattggtca caaccactcc agccaagaca tcattgtggc ctgctagata cttggttgct
    11581 gaatggagaa cgatatctgc tccatcttca atcggacgtt ggtagatagg gctatagaag
    11641 gtattgtcca ccaccacttt ggcaccctta gcatgagcca attttgctag tttttcgata
    11701 tcaaattcca acatcaaggg attggttggg gtttcgatat agagaacatc cacatccttt
    11761 tctaactcgg caatcaactc ttcttctgta ttggcatagg taaaatggaa atgaccttcc
    11821 tgctccactt ggttaaacca gcgaaaagaa ccaccgtaaa gatcacgcac tgccaagacc
    11881 ttacttccta ctggaaagac gctaaaggcc agtacaatag ctgacatccc tgagctagtc
    11941 gctagggcat agtctgctga ctcaatagcc gccaagactt cctcagcctt actacgagtt
    12001 ggatttttag tgcgcgtata gtcaaaccca gtagatcgac caaactctgg atgctgatag
    12061 gtcgttgaaa aatgaagtgg tgtcaccaaa gcacctgttg cctcatcaga cttgatccct
    12121 gcttgtgcta aaattgtgtt aatgtgtaat tccttgctca tacaattcct ccaaatctat
    12181 agtaactatt gtaccactta ttttcatcaa ctcattttct tcttttcaag agctagttat
    12241 agtttcaaac tatataaaaa gggagttttt cctgctccct ttaatagact ataaaatggt
    12301 gaatctcaaa agacaccttc actctatcat ttgctcctgc acaaaacgag cataacgctc
    12361 atgattttcc agtagttcct tatgagttcc tgagccagtg attttcccct cctctaagaa
    12421 gaaaatacaa tccacatctt ttaccgttga caagcgatgc gctataatca caaccgtctt
    12481 ctcctttagt acagaataga ggctactgat aatcgcatac tcagaatccg catcaagatt
    12541 agcagtggct tcatcaaata taagaatttc agcatctttt aagtaggctc tagctatttg
    12601 aagtctttgg cttcgccccc ctgacaagag tcgtccgcgt tcaccaactt cagtatctag
    12661 tccctctttc atggagcgaa tctcatcacc tagtgatact aagtctagca ctttcatcaa
    12721 ttcatcatca gttactaagc gattcaaacc gagacaaaga ttgtcacgaa tactgccaga
    12781 taagactgca ttattttgtg aaacccaagc gattttactt ctccattctt ttaagttaaa
    12841 atcatatata cttgattgct ccattagaat atctcctgaa agcggtttat aaaaccgctc
    12901 taacaaacgc acaatcgttg attttcctga tccagatggc ccaacaaaag caattttttg
    12961 ccccttgaaa attgaacaag taatatcctt taagacaggt cgattttcat cataaccaaa
    13021 atagacatgg ttaaaattca acccttgtcc tgataccgat tttcctccct caaatttttc
    13081 tttaggaact gcaagcaagt tctccagtgc aactgaagat cccttgctac tagaataaat
    13141 agttacaaaa ttagctatat tactaatagg attaagtaat tgaaagaggt aaatcaaaaa
    13201 cgaaaccaag gttcccacag atatatatcc tgcgctgacc cgataacccc cataggttag
    13261 catcacaact atagtcgcaa agataaataa gagagcaaac ggggtctcaa aagaagtaac
    13321 cctatctgat ttcagtgaat tgttttgtac cctttcaata caattatcca aaacatcctg
    13381 tacacttttc tctgcttggt tagtcttaat taattcatgt tcttgaatct tttcagtcaa
    13441 ttgccctgtt aaaaatccga tttcctcctg taaacgacga ctatactttt cactgatatt
    13501 ggaaaggggc aagataataa acatcataca aggaagagtg atgaataaaa gtagagaaag
    13561 attccaatca agactaaata agactacaat ggaaccaagt accataacta aactcagaat
    13621 aatatttggg aaagtcgtaa ttaaaaactc acgaatgaca ctcgtgtcat tgacaatggc
    13681 agaagtcaac tccccacttt ggctcttatc aaagaaggat ttctctgcat aaatcaaccc
    13741 ctctatcact tttttcctga tttttgctat ctttttttca cccgattgac taaacagata
    13801 gtaaccaata gaagaaaaca aggcttgacc aataaaaatc aaaaacgatt gaaatacttt
    13861 ggaacctata ttttcaatag aactcccatc tattaaacct tttaagataa ggggaagcaa
    13921 caaagcaagt agactagaca gaacaaggaa gaaactcccc ataatcacct tagtatctac
    13981 tcttaataat tttaatttca taaatactcc ttataatatt tcaacggata aagtcgggaa
    14041 taactcaatt tgaggataaa atctaataaa tcttcctata acaaaacgca taacatctag
    14101 gattttatat acctgatatt atgcgttttt aagcacaaag acttcttaca caaacttatc
    14161 tacaattaga ttttatttga catgttttgc caattcttct tgggcttttt tattggattc
    14221 ttctttttct ttcaaccatt tttctctggc ttttgcatat tcgtctgttg tgacaatctt
    14281 atcttgtact ttgaggtatt tatatgattc aacccctttt gtaccggtta aaccataggc
    14341 agcagcaaat ggtacggttc ttctcaatga tggtgttccc ccacgcgaaa cacttggaag
    14401 aactaaagaa ctatcaatca accaagcttg aatatcagca tatttctcat aacgtttggc
    14461 tggatcttgc tctttattag cttcttccaa catttgagta tagacatcca gtccaacttc
    14521 cttagccttg tcattggctt ctccaggctc tagtccaaga ttttgtagaa ctcctccact
    14581 attagtatta aaaatatcga gataggttga cgggtcttga taatcaggtc cccaaccgcc
    14641 atgatataaa tcatagtctt tctgagcagc tgtttgagca aagtagcctg aactgtcaaa
    14701 ctcatctgat gttaattgct gaatgtcaat cactacatta tcagaaccta aaacagattc
    14761 aattgattgt ttgatagaac taactccttg tatgcctact ttatctgtta cttccacagt
    14821 cttatccaag tggattggga attgaacacc ctttgcttcg agttctttct tagcttccgc
    14881 aaacttagcc ttggctttct caggattgta gtaagggtct tgaccatccg caaagttgat
    14941 accttgccat tccttaccat agttgaccat cttagaggct acaacttcac caaagtcttt
    15001 tcccttgata ctgacaaagt ttggaggaac cactaggtta cgcaaaatct ttgttgcacc
    15061 ttctttccct tcagactgag ccccataaga tgttctgtca aaagcaaaat tgatagcctg
    15121 acggaagttt ttattgagaa ctgcttcctg agtcgatttc ttttcaatgt cacttgtttt
    15181 agaagtataa ttgtaagact tcctatctag gttaaaatta aagaaatatg aagttgaatt
    15241 ttgcatacta tagatgatat tgtttttgta tttttcttta atcccttcat agctggagct
    15301 gttaggaaaa agacgagccg tagtataagc accagctgta aaattacgtt ccagtgattc
    15361 ttggtcgcta ccatcatagt aggtcaattt cacatcgtct acaaagacat tcttagcatc
    15421 ccagtaatta gggtttttct tatattcaat agcagatttt gagacaagtg ctttcatcaa
    15481 gaaaggtcca ttgtacaaaa tactagatgg atccgccttc ccaaaatcat ccccttttga
    15541 tttcaggaaa tctgcattaa caggaaaaag tatcgttgca agtgtttttg aattccagta
    15601 aagctctggt ttaaccaaag tatattgaac cgtttggtca tcaagtgcct tgacaccgac
    15661 agttgaaaag tcgcttgttt taccagtgat atagtcatcc aaaccagcaa cagagtcctg
    15721 cactagatac aaggcttctg attttttatc agctgcatat tgcaaacctg tcacaaaatc
    15781 ctgggcagtt acaggcgcat attcttctcc ctcagaagta aaccacttgg catccttacg
    15841 aagtttgtag gtataggtca aaccgtcctg agaaacagtc caatcctctg ctaatgatgg
    15901 aataatattc ccatattggt cattttctaa taacccgtct accaaatttg caacaatatc
    15961 ggatgttgct gcgcggtttt ctgctagata gttcaagcta gatggatcac ttgaataaac
    16021 atagttgtag gtttttgacg ccgtgctaga atttccacac gcgctcaata aaactcctgt
    16081 acccaggaca agacctgcca aggttagata tttgctctta gactttttca tttccgaaac
    16141 ctcctgcttt aaatatttgt tttattatac aactcttggt ttgtttagtc aattgttttt
    16201 tccaaaaaat caaaaaaaac ctcattttct atttttgaaa gataatttta gctattttta
    16261 cgctaaaaaa ggaataagtt tcaagttctc ctaaaagatt gttcaactta ttccttttat
    16321 ttataaatgc taccttacga aagcttaaat tttgctcgca ggcgatctgc ttgggctttt
    16381 cctattacct tatctaacaa ataggtacgc agactcataa ccatataaag tccacccccc
    16441 atggcaccga caagagctac ataaaagaag ctccacaaac gtccacttgg ttggaagaaa
    16501 aatcctaaca gccactggat ggttcctatt aacagaaaca tgactagggt cagcaaactg
    16561 attaaaatgg ttcgcttcaa aatcaccttg cgcttgacac cagttacttt acaaatatcc
    16621 cgatacatca agacgttagg aatgatgaga gcaatggttg ttgaaatcaa aggaccataa
    16681 ctgtggaaga gggcgatggt aggtagttgc aagactagct tggcaataga accatagata
    16741 aaatagagaa cggcctttcg gttgcggaac atggcctgaa gcattggaga caagaccatg
    16801 tacaagccta aaataataga ctgcaaaact gcaaagacaa ataagcccag agccaaacta
    16861 tctggcttac catagaagac cgtataaaga ggttctccta ccataaccac tccaaccgtt
    16921 gctggtagca agaacataaa gagtagggtg agactgtcct gaacgagacg agaagctgct
    16981 ttcaagtccc ccttgacata gttttccgtc aaaagtggca aaccaacact cccaatcgaa
    17041 acccctacag aaatcaaaat catcgtgatt ttattaggat tggctgagaa ataagaaaac
    17101 atgacaacca agtcctcatt gctgtagttg gtaaaccagc tcatactatt gataaaggtc
    17161 agctgatcca aaatctggaa gagctggatg gcagaccctg tcaggataaa aggaatggct
    17221 tccttagtgg tatcaaccaa gagacgctta ctgttaatct tatctcctgt ttcaaagact
    17281 cttttgagtg aaccttcttg ggcaaggaaa taaatcaaga ctgcaaaact ggctaccata
    17341 ccgacaaagg cagcaaaggt tgattgggta acggctgcta gataatctcc tgaaccgagc
    17401 ttcataatga taaaggttgc taggagcatc cagataacac gaatgacctg ctcagcaatt
    17461 tggctcatgg catagggttt gaggttattc atcccttgga aaaatcctcg gataacactc
    17521 atagacggga aaatcaagac tccccaagcc aagctttgca tgattgggat caagtctttg
    17581 cccacgccag acaagtctgc tagccaagga gcaaagacat acaagactaa agcaaaaacc
    17641 aggcctagtc ctgtcataaa gcctaagaag ctccgaatca gggcaaagct atgctcttct
    17701 tctcgcatgg tattatactt ggcaacttgc ttggccaccg caactggaat ccccgctgtt
    17761 gaaaccaaca agaaccaagc atagatattg taacccatgg taaagagacc atttgcctta
    17821 gctgcataag cccccatcca gatgtaccaa gggataatat aaacagcccc gagtaggcga
    17881 ctgataaagt tactagccgt tagccaagca gtcccccgta acatctgggc ctgctggtga
    17941 ttgttttcgt gcgacataga ttcctcattc aattttgata gctaggaaaa actccttatc
    18001 ttccattata aacttttcct tgttacttgt aaatttacga ctttcggttt acaatagaaa
    18061 gtatgattaa gattgaaacc gtattagata ttttaaagaa agatggcctt tttcgagaaa
    18121 ttattgacca aggtcattac cactacaact acagcaaagt tatttttgat agcatcagct
    18181 acgacagccg aaaagtaaca gaagacactc tttttttcgc aaaaggcgct gcctttaaaa
    18241 aagaatacct tctttctgct ataacacaag gattagcttg gtatgtagct gaaaaggact
    18301 acgaagtcgg tatccctgtc atcattgtga acgatataaa gaaagccatg agtttgattg
    18361 ccatggagtt ctatggtaat ccacaggaaa aactcaaact ccttgccttt actggtacta
    18421 agggtaagac aacagcagcc tatttcgcct ataacatctt atctcaaggg catagacctg
    18481 ctatgttgtc gaccatgaac acaactcttg atggcgagac tttctttaag tcagcgttga
    18541 caacccctga gagtattgac ctctttgaca tgatgaatca ggctgtgcaa aatgaccgta
    18601 cccacctcat catggaagtc tccagtcaag cctatctggt caaacgtgtc tatggtctaa
    18661 cctttgatgt gggagttttc ctaaatatca gcccagacca tatcggcccg attgaacacc
    18721 ctagctttga agactatttc taccacaagc gtctcttgat ggaaaatagc cgagcagtca
    18781 tcattaacag tgacatggac cacttctcag tcttgaaaga acaggttgaa gatcaagacc
    18841 atgatttcta tggtagccaa tttgataacc aaatcgagaa ttccaaagcc tttagctttt
    18901 cagctacggg taaactcgct ggagattatg atatccaact cattggcaac ttcaaccaag
    18961 aaaatgcagt tgctgctgga cttgcttgtc tctgtctcgg agcaagtctt gaggacatca
    19021 aaaaaggcat cgctgcaacc cgcgttcctg gtcgtatgga agtcctcact cagaaaaatg
    19081 gagccaaggt cttcatcgac tatgcccaca atggggatag tctgaaaaaa ctcatcaatg
    19141 tggttgaaac tcatcaaacc ggaaagattg ctctggttct gggatcaaca ggaaacaagg
    19201 gagaaagtcg tcgtaaggac tttggcctcc tcctcaatca acaccctgag attcaagtct
    19261 ttctgactgc tgatgaccct aactatgaag acccaatggc cattgcagat gaaattagta
    19321 gctacatcaa tcatcctgtt gaaaagattg cggatcgcca agaagccatc aaggcggcaa
    19381 tggctatcac aaatcacgaa ttagatgcag ttattattgc gggtaaggga gccgattgtt
    19441 accaaatcat ccagggcaag aaagaatcct acccaggaga tacagccgtc gcagaaaatt
    19501 atttataaga atagaaaaaa tcaagggaaa atgaaaccct tgattttttc ctattattta
    19561 gtaaaaacgt ttttcaaacc ttcaacggca ccttctacag caccttttgc gtcttctaca
    19621 acgtcttttg ccttagcaac tgttttttca acagctcctt caagttctgt cttgctgtct
    19681 ccagtaactt taccaaaacc ttctttgaca gcgcctgttg cttgttccaa tttgttttca
    19741 agtgacatat gattgtctcc tttagtttat tccgatatgt gttaccggtt acatatagtt
    19801 tataccgaat actaaggaaa gtcaaacaat gtgctcagaa acaagaaatc acgctaagta
    19861 gaaagttaat ctctccttat caaaatcgat agccaactca tactttctat cttcattttg
    19921 cacaatatag cctaagacaa ccaaactgtc cacaaagata tcacggcatt tctgcataag
    19981 gtggtctttt ttgagaaatt tcaacaaaaa agccgtcata tacttgagtg catactcagg
    20041 attaacatct cctaaaatgt catagagctc ctgctgtttt tctgtcaaag gatactgctg
    20101 tttgaccttg taaaaataat tggacagggt cattttaatg cgcgcaaagt ccgtcttttc
    20161 aactaaaata gctgcattga tttgattgcg caattccgtc tcaaaactct gctccaacaa
    20221 ggcttgatag accggactag cttctctgac aaaaatctct tgatccagtt caagactatc
    20281 aagtgattca agcgtaggaa aattgaggta atagcgctta ttttcacgta gaatcaagcc
    20341 tgcctttata tactcttcca tgagtttatc aactgcaaca tctggaaatt gagccttaat
    20401 ttcccgtaga atcacatcct catactggtc cagatagcgg atcaattctc caaaaatggc
    20461 tgtctcgtca aacgagatgg attaaaaatc tgaatcatga agattccttt ctttacattg
    20521 taacagaggc gatgctgcca actgactagg attggtacca gcttggttca gaggaacagg
    20581 cagacctagt tctatgtaat actccctcca aaaatcacta atctcctgct ccccatctcc
    20641 aaatttcata ggaatagttt caaaaatagg taggatttct gctatatact gggagcagta
    20701 gaaaccagct gcatctggat agaaagaagc attgtagggt gctccaagat gtttgcaagc
    20761 tctttccttc accgactgga tatccatttc tgggtaaaca tagaggtcgt ataaatgatt
    20821 ggactcaaag aagtctgccg gttcttgaca gacaacacca gcctgtccac tagcatgata
    20881 aatcatccca tccaaataaa tggcaacatg gctatagtta cctgtggaag tctggatggc
    20941 ctgtcccatg tctgacccat ctctcacaaa aatcaaatcg ccattttcta acatacttca
    21001 ctcctagaaa aaaggagccg aaactccttt cgatataagg caaactagac tttccgattt
    21061 tgagctgaca cccaaaatct tacgcattaa agctttcagt caattgaggt accacttgtt
    21121 tcttacgtga aacggcacca gcaaggaagg catgattgtt ttcaagtttg aagttgaaag
    21181 ccgcttcgac cttgtccata ttggcaccaa gagccaagat ttctgagttt gagttgacga
    21241 tatctgtaat catcaagaca aagtcagagt agccgtttga ttcgttggca gcttgcattg
    21301 cagcttcaat ttctgcttgg cgttccaaaa cttcagcgat gtcaactgtg ttcacttggg
    21361 caacacggac attatttccg ttgagttcaa aagtcttagc atcgatatca atcaattctt
    21421 cagcagattt gctagccaag ttggtaccag ctttcaacat tgccaaacca tattcttcca
    21481 agttcacacc agccaattca gccaattcag gagcaatgat tttatctgtt gggtgtgttg
    21541 ttggtgattt caaaagaagg gtatctgaaa tcaaacctga aagcatcaaa cctgcaatct
    21601 ctttaggcac agctacacca tgttctttga acatacggta aacgattgaa gacgctgatc
    21661 caactggctc caaacgcatg taaagtgggc ttgcagtttc aaagttagcc acacggtggt
    21721 ggtctacaac accgtaaact tctacttcag cgatatctga tacagattgt tggaattcat
    21781 tgtggtcagt caagataact tgctctgccc cctctgcttt ggcagaagtg ataacacgtg
    21841 gtgcttccac accaaaatag ttcaagacaa aggctgtttc ttcatttgga gttccaaggg
    21901 caacagcttc cgtatccaaa ccgtaagctt cttttgcaag gtaggcaaaa gctacagatg
    21961 atccgatggc atctgagtct ggattttggt gaccaaatac tagaatcttg gacatgataa
    22021 tacctcattt tgtttatttt ctttattgta gcattttttt cgctttttga caaaggtaag
    22081 aggagtcaaa ggactcccca cgattcttca aaataactga gtaaatttct atcttgattt
    22141 tcagataaaa attcttcctt ctgtggcctc ttcttacgct tgagaagagc ttcagccgac
    22201 atggcttctt ccttactggc aaaaccttga gcatagataa gtttgactgg caagcgtgct
    22261 cgtgtatatt tggctccctt cccactattg tggatagcga ggcgtcttct cacatcagtc
    22321 gtatagccta tatagtagga tccatcacga cactccagaa cgtacatata agccttatga
    22381 tccataataa atctcttcga tttcgggcgt ataagagcca tcatcattgt ggacaatcaa
    22441 aggaggtaag accttaaagc cacttgttga gccatccttg atcgcctcaa tcaaaagcat
    22501 attggcttcc ttttctcttt ttggataaac aaactgcagg cgcttagggg ctagattatg
    22561 tcgttttaac gtatccaaaa tatccagaag tcgatcagga cgatgaacca tggccaaacg
    22621 cccattagac ttgagaatac tctgggcact acgacagatt tcttccaaat tagtcgtgat
    22681 ttcgtgtcga gccaagagat aatgttcact ctcgttcaga ttagaataag gatccacctt
    22741 gaaatagggt ggattacaca aaatcatatc caccttactc ccctgaatgt gagcaggcat
    22801 atttttcaaa tcatcgcaga tgacctgcat ttgctcctct aatccattca aacggacaga
    22861 gcgttcagcc atatccgcca aacgctcctg aatctcaaca gacaatatct gtgcttgagt
    22921 acgagtgcta gcaaaaagcc ccactgctcc attcccagca cagaaatcca caatcaaccc
    22981 cttcttagga aaacgtggaa atcgtgataa gagaacacta tccaccgaat agctaaaaac
    23041 ctctctattt tgaatgattt tgatatctgt cgaaaagagc tggttaatgc gctctcctga
    23101 ttttaataat tgttcttctt ccatggtcct attatagcaa atttatatta acatcacaaa
    23161 aaatataaaa ctctaaacta cttcgtcttt tttaaatggt gcagggcttc tccagtccag
    23221 attggtaaca ttcgtcgaaa gggagcaaaa ccgtagttaa agcggtcgct tgaaaagcgt
    23281 ctccgtctag gaaactggta cttttcttcc tccaaagtgc ggatagaaag actggctttc
    23341 cccgtaaatt catctaaatc cactacctga acttgaacct cttcatcgac tttcaaggtt
    23401 tcatgaatat tttcaataaa tcctgtccga atttctgaaa tgtgaatcag ccccgtatca
    23461 cccgtctcta actcaacaaa ggcaccgtag ggctgaatcc ctgtaatacg cccctttagc
    23521 ttatcaccga ttttcatctt agtcctcgat ttcaatagtt tcaattacaa catcttcaac
    23581 tggcttgtcc atagctcctg tctcaacagc agcaatggca tccaagacag cgtaagatgc
    23641 ttcatcagct aactgaccaa aaaccgtgtg acggcggtct aggtgaggtg tcccaccttg
    23701 attggcatag atttctgcaa tcggttctgg ccaaccacca cgagtaattt ctttcttaga
    23761 ataaggtagg tgttggtttt gcacgataaa gaactggctg ccgttggtat ttggaccagc
    23821 atttgccatg gaaagagcac cacggatatt gtaaagctct tctgagaatt catcctcaaa
    23881 agattcgccg tagattgact cgccacccat accagttcca gttgggtctc caccttggat
    23941 cataaagtcc ttgataatac ggtggaaaat gacaccatca tagtagccat cttttgaaag
    24001 agatacaaag ttagccactg ttttaggagc atgttcaggg aaaagcttga tacgtaagtc
    24061 tccgtgattg gtcttaatag tcgcaagagg accttctact gtttcaatgt ctacttgtgg
    24121 aaaatgcaat tctttttcta ccataccaaa tacttctaag gcatcaaaaa tgccatcttc
    24181 ttctaatgtt tttgtaatat aatctgcttt ttctttgatt ttatcatgag aaattcccat
    24241 ggcaacgctg attccagcat aatcaaagag ttccaagtcg ttgagaccat ctccaaaaac
    24301 catgaccttc tctggtttca agccaaggtg ttccacaacc ttttccaccc ccgtcgcttt
    24361 ggagcctgaa atcggcacaa tatcagacga atgttgatgc caacgaacca tgcgaagttt
    24421 gtctgagaga ctgtcaggca agtgcaagtc atctccctta tcttcaaaag tccacatctg
    24481 atagatatct tctttttcat ggaaatcggg atctacatct aagtcgggat aaattggatt
    24541 gatagcttca ctcatcatat cggtgcgagt cgacaacttg gcatcatgac tcccaaccaa
    24601 gccatactca attccttctt gcttagccca agagatatac tcctcaacat ctgacttttc
    24661 aatctgatgc tgataaatga cctgaccttt tttatcttcg atataagctc cattcaaagt
    24721 tacaaaaaag tcaggcttga gatcacgaat ctctggaaca acaccaaaaa tgccacgtcc
    24781 agaggcgatt cctgttaaaa ttcctttttc acgcaactgt ttaaaaacag tgggaattgt
    24841 agttggaata aaccctgtct ttgaattccg caatgtatca tcaatatcaa aaaagacaat
    24901 cttgatcttc tttgccttgt atcttaattt cgcgtccatc tcactacctc tttcaatcta
    24961 actctttcca ttatatcata aagtaggcaa atcccctatt ttcaaaaagt ttatcatttt
    25021 tattttaatt tcttggatga gaaaagagac atatttatga aaaagctcca tcgtgctttt
    25081 aatgtgttct cttgttttca aactcgtaaa aagggagcca ctgagcctaa ctcgctctct
    25141 catttcaaat cttgtgaaaa aagacccgtt ggggtcttaa ttcgctttct tgttttcaag
    25201 ctcatgaaaa agagacccaa tcgggtcttt tctttaatct tcgtttacga aaggcatcaa
    25261 agccattacg cgagcgcgtt tgatagctgt tgttacttta cgttggtttt tagctgaagt
    25321 tcctgttaca cgacgaggaa ggattttccc acgttctgaa acgaaacggc taagaagctc
    25381 agtatctttg taatcaacat attcaatttt gtttgctgcg atgtaatcaa cttttttacg
    25441 gcgtttgaat ccgccacgac gttgttgagc catgtttttt ctcctttata agtttagttg
    25501 tccattagaa tggtaaatca tcatctgaaa tatccaatgg gtttgttgct ccaaatggat
    25561 tttcattacg tgaaaagtct ggtactgaat ttgtaggtgc tgaatagttt gcagttggtg
    25621 cagagtaagc tccacctgtg tgaccctcac gcacactacg gctttccaac atttggaaat
    25681 tctcagccac gacctctgtc acgtagacac gttgtccttg ctggttatcg taactacgag
    25741 tctggatacg acctgtcacc ccgataagtg agcctttttt agcccagtta gcaagatttt
    25801 cagcctgttg gcgccacata acgacattga taaaatcagc ctcacgttca ccattttgac
    25861 tcttaaatgt acggtttact gcaagagtaa aagtcgcaac tgctacattt gatggggtat
    25921 aacgcaactc agcgtcacgt gtcatacgcc ctacaagtac aacattgtta atcatagttt
    25981 accttcttac gcgtcaattt tgacgatcat gtgacgaaga atgtcagcgt tgatttttga
    26041 aagacggtca aactctttaa gagctgcatc gtcatttgct tcaacgttaa cgatgtggta
    26101 aagtccttca cggaaatctt ggatttcgta tgcaagacga cgtttttccc aagtttttga
    26161 ttcaacaaca gttgcaccgt tgtcagtcaa aatagagtca aaacgtgcta ccaaagcgtt
    26221 tttagcttct tcttcaatgt ttggacgaat gatataaaga atttcgtatt tagccattga
    26281 tatgttcctc cttttggtct aatgacccca agactttgca aggggtaagt gaggttcgct
    26341 cacaataaac tattatacta gaaaaaattt ttttacgcaa gtaaaaacac tagaattcga
    26401 aaaaacgcca catgggcgtt ttcctgttct tatggtttga tacggtgcaa catacgtggg
    26461 aatggaatag cttcacggat atgttttgtt cctgctgcga aggttaccat acgttcgata
    26521 ccgataccaa atcctccgtg tggaactgta ccgtatttac gaaggtcaag gtagaattca
    26581 tattctgtac gatccatgcc aagttcatcc atcttagcga caagggcatc gtaatcttcc
    26641 tcacgcatag acccaccgat aatttctcca tagccttctg gagcaagcaa gtctgcacaa
    26701 agcacgcgct ctggatttcc aggaactggt ttcatgtaga aggccttgat ggctgctgga
    26761 tagttcatga caaatgttgg cacaccaaag tggtttgaaa tccaagtttc gtgtggtgac
    26821 ccaaagtcat caccatgctc aagatgctcg tagtcagcat cttcatcatt ttcatgctct
    26881 tgcaagaggt caatggcttg atcgtaagtg atacgtttga atggctctgc aatgtagcgt
    26941 ttcaagagtt ctgtatcacg ttccaaggtt tccaaggctt gaggcgcgcg gtcaagaaca
    27001 ccttgtagaa gagctttcac ataagcttct tgcaagtcaa gcgactcatc atgtgtcaag
    27061 tatgagtact cagcatccat catccagaac tcagtcaagt gacggcgtgt ttttgatttt
    27121 tcagcacgga aaactggacc aaagtcaaag acacgaccaa gagccatagc ccctgcttct
    27181 aggtaaagct gacctgattg gctcaagtag gctggcattc cgaagtagtc agtttcaaag
    27241 agttctgtag aatcttctgc cgcatttcct gaaagaattg ggctgtcaaa cttcataaaa
    27301 ccgttcttgt caaagaactc ataagttgca tagataatag cgttacggat ttgcaacaca
    27361 gctacttgct tacgagagcg tagccacaag tgacggttat ccatcaaaaa gtctgttccg
    27421 tgttcttttg gtgtgattgg gtagtcttga gattcaccga tcacttcgat gtctgtgatg
    27481 tccaactcat agccaaattt agaacgttcg tcctctttga caatacctgt cacataaaca
    27541 gacgtttctt ggctcaagcg tttgataaca tcaaacttct caagtcccac ttcttcacca
    27601 aatttttcga caaagtttgg tttaaaagcc acaccttgaa agaaggctgt tccatcacgc
    27661 aattgtaaga aagcgatttt cccttttcct gatttgttgg caacccaagc gccaatcgtc
    27721 acttcctgac caacatagtc ttttacgtca ataatcgtta cacgttttgt cattattttt
    27781 ccttttcttt tttattcttt atggcaaacc acctctatat tgttcccatc caggtcaatc
    27841 ataaaagcag catagtaaat cggatgctca cttcgataac caggagcccc attgtctcgc
    27901 ccacctgcct ctaagccagc ctcataacaa ggctgaactc cttccttatt ttctgctaaa
    27961 aaagcaaaat gaacaggatc ttgtgttccc tgagtcagcc aaaaatcacc accaggatga
    28021 gggctgttcg gggatagaaa actaattaga gaactagtct taaaagccat tttatagtcc
    28081 aaaggagcga gaaaactcct ataaaatcct tctgaaattt gtaaatcctt taccttaatc
    28141 tcaaaatgat caatcattct cactacccat aaatgctttc aagcgttcga ctgcttcttt
    28201 aagcgtgtct aggtctgtcg catagctgag gcggacattt tctggtgctc caaatccagc
    28261 tcctgttacc aaggccactt cggcttcttc taagatagca gttgtaaagt ctgtcacatc
    28321 cgtgtagcct ttcatctcca tggccttttt gacatttggg aagagataga aggccccttg
    28381 cggtttgacc acttcaaatc ctggcacctc tgcaaggagg ggatagatgg tattaagacg
    28441 ttcctcaaag gcctgacgca tgctttctac agtatcttgc tcacctgata gagcctcaac
    28501 tgctgcatat tgggctactg ctgacggatt cgaagttgtt tgacctgcaa tcttggacat
    28561 ggcagcgata atgtctgctt ctccaacggc ataaccaatc cgccaaccag tcatggcata
    28621 ggttttagac acaccattga tgaccactgt ttgcttgcga atcgcttccg ataggctaga
    28681 aatcggtgtg aactcatgac cattataaac caagcggcca tagatatcat ctgctaggat
    28741 gagaatatca ttttctacag cccagtttcc aattgccaag agttcctcac gggtgtaaat
    28801 catacctgtg ggattagatg gcgaattcag caccaaaacc ttggtcttgt cagtgcgagc
    28861 tgcttctaac tgatctacgg tcaccttaaa gtgattgtct tccttagtag aaacaaagac
    28921 gggaacgcct tctgccatct tgacctgatc tccatagcta acccagtatg gggttgggat
    28981 gatgacttca tcacctggat tgaccacagc cataaagaag gtatagagag aatatttggc
    29041 tcccgcagcg actgtcactt gatttgacgc tacagaatag ccgtaaaagc gctcaaagta
    29101 gctattgacc gccgccttaa gctctggcag acctgaggtt actgtataaa aagaagcacg
    29161 cccatctcga atcgatgcaa tggcggcatc ttggatattt ttgggagtag tgaaatctgg
    29221 ctcacccaag gttagagaca aaatatctct gccctcagcc ttcagtgctt tggcacgggc
    29281 tccagcagcc aaagtcacac tttcttccat ttctaaaaca cggttggata atttcatagg
    29341 ccctccttgt tgaccaatgc tcctgtttca aaatctacta gataaaaatc agatcctgac
    29401 ttgacttccc agattggctt atcttgataa cgaccaaaga taatcttgtc aatttcgcca
    29461 gctccctttt ccttagaaac cgtttctgct ttttcttgtg aaacaccctg atttagctga
    29521 taaacgtaaa tcttatgatc atctttacca atcaggacag caagcgcttc ttgctgttta
    29581 ttacgaccaa gaacgctgta ataagattcc aagccattgt ataaatcaac ctgatcgacc
    29641 tgctctaatc ctgcatactg ctgagctaat ttttctcctt cacttttagc tgtttgatag
    29701 ggtttcatgc taagagaaac catatacaga aaggaagcac tgataaccac aaacaaaatc
    29761 gtcatcccta gaccatactg ccacagtaga ttattttttg ctttgttttg tctttttttc
    29821 actcgtctat tttaccatct attaagcttt attacaagtg aatataagaa tactcttcga
    29881 aaatctcttc aaaccacgtc agctttatct gcaacctcaa agctgtgctt tgagcaacca
    29941 attctatttc tcccttcaaa caaaaccgat tttgaaagtg aaacagttct tactttttca
    30001 gtcacaaatg attagagttt ccgaaatttt acaattttca aataaactct gagcaaattt
    30061 cttgcaagtt cttttgtttt gttgtaatat attttataac aacgagagag ttctcgaaat
    30121 tttaagaaaa aggagacaca tcatgtctaa aaaagtatta tttatcgtcg gatcactacg
    30181 tcaaggttct ttcaaccacc aaatggcgct cgaagctgag aaagcacttg ctggtaaagc
    30241 ggaagttagc taccttgatt attcagccct tcctctcttc agccaagatt tggaagttcc
    30301 aacacatcca gctgtagctg ctgctcgtga agcagttctc gttgcggatg ctatctggat
    30361 tttctctcca gtctacaact tctctatccc tggtacagtg aaaaacttgc ttgactggct
    30421 atctcgtgcc cttgacttgt ctgatacacg tggcgtttct gcccttcaag acaagtttgt
    30481 cacagtatca tctgtagcca atgcagggca cgatcaactt ttcgctatct acaaagacct
    30541 cttgccattt atccgtacac aaggcgttgg tgatttcact gctgcacgtg ttaatgactc
    30601 tgcctgggca gacggaaaat tggttcttga agaaacagtc ctaaactcac ttgaaaaaca
    30661 agctcaagac ttggtcgaag ctatcaagta actaacactc aataaaaatc aaaaagcaaa
    30721 ctaggaagct agccacaagc tgctcaaagc actgctttga ggttgtagat agaactgacg
    30781 aagtcagtga catatatacg gtaaggcgac gctgacgtgg cttgaagaga ttttcgaaga
    30841 gtataacata ataaaagcga acaagactac ttttctgaca ctcagaagac tagcttgttc
    30901 gctttttttc tcatttataa actaaaacag ctgatgatac atattgccaa atacaaaata
    30961 tctgatttct atacttcctt tacaaaaact aatccctgtg gttgtgacaa atcttctcgg
    31021 taaacaaatc cagcaaagtt caagcgacgt gcttccccca cagtttgtac ttgattttct
    31081 attaaagctg ttagaaaggc cccgcgcgct ttcttggaga tagttgagtg aatcttcagc
    31141 tgaccgcctc tatcctccat gaatttgaag gtcaccatct ttgctctgat ttccttagaa
    31201 aatacagtct caaactctga tgacaagaga gagaaaatca cttcttcctt cttcagagct
    31261 tcatcataga ctgccttcca atggctcttc aaagccttac cagcgacttt taatttcatc
    31321 aaaaaatcca aacggtgagg agccatgggt gacaaggctg gaacaacacc gtacaaagcc
    31381 gaggtaatga agacatgatt ttcaagataa tcttgttccg cctcggtcag cttatctctc
    31441 ttaatgttgc ggtacataag cccatcaaaa agtttcaagg ctggatagtg ttgagcagtt
    31501 tgccttttca aagcttggat attttgaaat tcttccgccg ctttctcagc tgataccttg
    31561 tagaaactct ccaattgact ggcagaatag agagccaagg catcaagcac ggcctgactt
    31621 tctggtttta aaggaattgc ctcgatactt ggcaagtctg tgttcatttc ttttgctgtt
    31681 gggattaaaa ttttcatatt gatagtgtag catatttttt agccacaacc aagaaattca
    31741 tttgaaaaac ctcggtttga ccgaggtttt tctatttatt tgggccatcc taaccagaca
    31801 gccacgagaa caagggctgt gccagctaaa cttgttaaga tagataagaa tttatctttt
    31861 ttctccttga actgagaaaa acctatcttc aaagcgagca gtccgagtag cattgaagca
    31921 accatcaaat aaaaacccat ttctttgtcc tccattaggc ttaatttacc ttattataac
    31981 atatatttct taaataaacc ttttttatac tcaatgaaaa tcaaagagca aactaggaaa
    32041 ctagccgcag gctgctcaaa acactgtttt gaggttgcag atagagctga cgtagtttga
    32101 agagattttc gaagagtatt attgtacttt aaaggtcttg agatagttgt cttttcctac
    32161 ttgaccttcg aaggttttac cattttcaag gtaaggaagg tcatcggata ctgaagcctt
    32221 taccttgtat atcttgccat caactttaaa gaagtagaca gtgtctccct tgataacagc
    32281 tgatttgagg tctgctacta ctcccttgat gctttctgtc gttgcattgt caatttcaag
    32341 gtcgttttta ttggcatact tgctgagcat ctcttccact gtagtagcaa cgataacatt
    32401 ttggtactcg actgcgtcta ccagggcgta ctctttgacc aagccagcat tgtcctttaa
    32461 gcccatgatg tagagaggct tgtcattgag gttgatgagg attgggaagg ttgctttgta
    32521 ggatttctcc tgaacagcac cttctgctga ttcacgggct gattcttctg tcgcagaagc
    32581 caagctatac ttagtgattt ctcctgttcg catattttca aggatgaaac caagattact
    32641 ctcatccgca ttagccgacg tcacacctgt gtagagatag atgtcattac cgatagacaa
    32701 gtaattatag cccttggtag tctgggtcac gtttttcttg gaaatcatgg cattcaagaa
    32761 accgtccttg tacttgccgt tgtagttaat ttgctcaatg gtttcctctg ctggatagat
    32821 cctgtccacc cattctggaa catctgataa gctgtattcc ttggtttctc catttgtagc
    32881 atccaagata atgactgaag caggacgagg aacagcaagt ccaaattgct tttggtaaac
    32941 cgttgctaca tagaaaggat tgccctcatc gtccacctca aaagatggag ttttaaagat
    33001 tttggtcggg tacttcaagc gcaggtgacg tttgacatca cggttaaaat actccgagtc
    33061 tgaatacttg attggtgtct tcaagtccac caaatccgca tttccagtta ccatgtccac
    33121 cttaatatac tcaccgattc ccttggcttg attgttaaac catttgatag ggtctgcata
    33181 ttctagtggt gtgacccgat aaggtttccc atcaattgtc aattgggtat aggtatctgc
    33241 cgctacgtat tgcgacacct tatcggttag ggaacccaag tagcggtctc caattttttc
    33301 agcagtactt ctatctagga taggaacctt actggtgtca ctcttaggaa attcagtaaa
    33361 gtctttttcc gtaaccgtga ctacattggc ataattttta gcctgaaaca tgctggaagt
    33421 taccaaggaa accaaagctg ccaagagaag aattcctcca atcgaagcta acagaatttt
    33481 ccctaaccga ttgattttga aaccctcaag atttaaggca gcttccgcct taccgtggcg
    33541 cacatgaacc gttttgacaa ggtttatccc cttgctaaag ccaaataaga ttgccacaac
    33601 taacaaatgc ccacagagga agaagagaaa ttcccagctg gtcaggttaa ggggcggtaa
    33661 aaagatatac caggtcgttg cgataaaaat aagttcaaag actattcgtt tcatttgctt
    33721 tcctcctaaa tgattcgtcc ttccaagtga tccagctcat gctggcaaat ctgagctggg
    33781 aagcctgtca aggtaatggt ctgttcctgc cacttgctgt cacgataggc aacccttatg
    33841 gtttcataac gcttagttga tctcacacct accaaggaca aacagccttc ttctgcctca
    33901 taggatcctt caaaggacag aagcactggg ttaaacatga ccacgggaac caagccaaga
    33961 ttaaagataa tcacgcgctt ctgcacccca atcatattgg cagctagacc aacacaggta
    34021 tcacgatttg ctaagagtgt atcctgcaaa tctctggcaa gataaaggtc ctcctgactt
    34081 gccggctgag acacttgaga taaaaataag atatccttca caattttctt ttccacttcc
    34141 tcacactcct cttgcttttt actatattat agcaattata gcacaaaagc cgataactgc
    34201 aaaccctttc cctcaactgt agcaaaaagc catccgaaga tgactttttt gctatttaat
    34261 ttctgtataa gttacttcca agccacgctt aacagctgga cgattggcaa ttttttctgc
    34321 ccattttact agattttgat aacttgaggc atccaagaat tttgcagaac cttggtaaag
    34381 atttccttga actaactgtc cataccaaga ccagatagca atatctgcaa tcgtatagtc
    34441 attgcctgca atataaggtt tctgagccaa ttccttatcc aataaatcca actggcgttt
    34501 cacttccatc gtaaaacggt taataggata ttccaatttt tcaggagcat aattgaagaa
    34561 atgtccaaat cccccaccta gaaaaggtgc tgcacctgct tgccagaata gccaattcaa
    34621 aacttctacc ttttccacag gattacttgg taaaaaggct ccaaatttct cagcaaggta
    34681 aagaagaata tgagcagact caaagactct tacgttttca gtacctgact ggtccaataa
    34741 ggctggaatc ttggaatttg gattgagctt cacaaagtct gagccgaatt gatccccatc
    34801 catgatagca atcttataca agtcgtaagc cgcttcctta aaaccagctt ctagtaattc
    34861 ttccaataag atagtaacct tcacaccatt tggtgttccc agtgaataaa gctgaaaagc
    34921 ttgttctcct tttggcaagt tttgttcgaa acgggcacct gctgttggtc tgtttagccc
    34981 cgtaaaagct ccttgattac tagcttcatc ctgccatacg gtcggtaatt gatatgctga
    35041 catccgaaac ctcccttaaa tcgcattctt gtcaaaaccg agtttgcgtt gaataaactt
    35101 aacgatttcg acgatgataa tcattgagaa gcttccagcc ataacaattc cccattgtga
    35161 caagtctagt ttggttacgt ggaagattcc ttcaagcggt tctacaacga ttgttgccat
    35221 gagaaggata aaggatacca agatggacca gttaaaggtc ttagacttga atgggccaac
    35281 tgtcaagatg gattggtaga cagacttgac attgtaggca tggaagagct gaatcaaacc
    35341 aagggttgca aaggccatcg ttagggcatc tgcatgaata gcatgattgt cacccacatg
    35401 aactgggtaa gcaatcgcaa ggccataaac actcataaca agagctgctt ggagtacacc
    35461 ttgataaatg atagaactca aaacaccacc tgagaagaag cttgccttgc gtccacgtgg
    35521 tttatgattc atgacaccag gttccgcagg ttcaacacca agagcgatag ctgggaaggt
    35581 atccgttacc aagttgatcc acaaaagatg aaccggctgt aagacatccc aaccaaacaa
    35641 ggttgatagg aagatggtta atacttcagc agtattagca gaaagtaggt actgaatagt
    35701 cttttgaatg tttgagaaga ccttacgtcc ttcttccact gcgacgataa tagtcgcaaa
    35761 gttatcatct gcaagaatca tatcagaagc ccccttagaa acctctgtac cagtgattcc
    35821 cataccgata ccgatatcgg ctgttttcag agctggcgcg tcattgacac cgtcacctgt
    35881 catggcaacg actttacctt gtttttgcca agccttgacg atacgaacct tgtgttctgg
    35941 agacacacgg gcataaacag agtattgacc aacgactttt tcaaattctt catctgacag
    36001 ttcattgagt tcagcaccag ttaaaacgtg accttctgta tcgtttgcgt caatgattcc
    36061 caaacgtttg gcaatggctt ccgctgtgtc ttggtggtca cctgtaatca taatcggacg
    36121 gattcccgct tccttagcca cacgaacagc ctcagcggct tcaggacgtt cagggtcaat
    36181 catcccaatc aaaccagtaa aaattaaatc attttcaagc tcttcagaag tgagattttc
    36241 tggaatacta tcgataatct tataagcacc tgcaaggaca cgcaaggctt gatgagccat
    36301 ttcagaattg tttgtatgaa tgagatttgt aaccttctca tcaatcggag caatatcccc
    36361 agccttatca cgaagaagac aacgttttaa gagttggtct ggcgcaccct tgactgctac
    36421 aaggaaacga ccatctggca atgggtgaac tgttgacatg agcttacggt cagagtcaaa
    36481 tggcaattca gctacacgag gatatttctc taagaaacct ttgacatcat agcccttgtc
    36541 caaggcatat tggataaagg ctgtttcggt tgggtcacca atcaagttac cttccacatc
    36601 gattttcgta tcattggcca agacaactga acgaagtagt ggcatttcaa gacctagttc
    36661 aatatcatca gctgagtcat gtagaaccgc atcgtagaag actttttcga ctgtcatctt
    36721 gttcatagtc agcgtaccag tcttatcaga agcgatgatt tcagttgaac caagtgtttc
    36781 aactgctggc aacttacgaa cgatggaatg tcgtttggcc aaaacttgag taccaagaga
    36841 aagaacgatg gtaacgatag caggaagtcc ttctggaatg gctgcaacgg caagggcaac
    36901 agaagtcaac aactcaccaa gtggattttt cccttgaatg aagacaccca ctacaaaagt
    36961 aacaagggca atgaccaaga tagcataggt caagacctta gaaaggttgt tcaagttttg
    37021 tttgagtggt gtatcagtct catccgcatc ttgaagcata ccagcaatat gaccaacttc
    37081 agtgtacata cctgtattga caacaacacc catcccacga ccataggtta cgtttgagtt
    37141 ttggaaggcc atgttgacac ggtcaccaat accagcatct gtcgcaagct cgactgacaa
    37201 gtctttttcg actggtacag attcacctgt caaggctgct tcttcaattt taagagagtt
    37261 ggcttctatc aaacgtaggt ccgctggtac cacgtcacct gcttcaaggg caacgatatc
    37321 gcctggtacc aattctttag agtcaatctc tgccatgtgt ccatcacgaa gaacgcgggc
    37381 aactggacta gacatggatt tgagggcttc aatagcttct tcagcttttc cttcttggta
    37441 aacaccaaag gcagcgttga tgataaccac agctaggatg ataatggcat ctgcgatatc
    37501 ttccccacca gaagtcacga ctgacaagat tgctgccgca actaggatga taatcatcaa
    37561 atccttaaat tgctcgatga atttgaccaa gattgatcgt ttctcgcctt cttcgagttc
    37621 attgtgccca aattcggcaa ggcgcttttc cgcctcactt gatgacaaac cttgctcggt
    37681 cgcatccaca gcctgcaaga cctcttcagg gctctgagta taaaacgctt ggcgtttttg
    37741 ttcttttgac atgtgtctcc tccttgacat tgtgtgcaaa acagactctc tttctgtcat
    37801 atcttttcac gacaaacaaa aagagacctg ttaatcataa caagtctcgc tgtttaagat
    37861 agggccggaa agcatacttt tcagcataaa attcggaatg acgacactat cacaggtttc
    37921 tgccagctac tcccttgagt agtaccatta taccaaattt tggggagttt tcaaagagta
    37981 aaaactgcct tatttgaatt tttccttgaa aaccagtata atggtagaat gctatgtgac
    38041 tagaaaggaa gttgaatgaa gcaatctatc tcaaatctca agttagctga gcgtggagcc
    38101 attatcagta tttcgaccta tttgatcttg tctgcagcta aattagcagc tggtcatctc
    38161 cttcattcat ccagtttggt ggccgatggt tttaataacg tatcggacat cattggaaat
    38221 gtggccctct taatcgggat tcggatggcg cgccagcctg cagaccgtga ccaccgtttt
    38281 ggtcattgga agattgaaga tttggcaagc ttgatcactt ctatcatcat gttctatgtc
    38341 ggtttcgatg ttctaagaga taccattcaa aagattctca gtcgggaaga aacggtcatt
    38401 gatcctcttg gtgcaactct aggaatcatt tctgcagcga ttatgtttgt ggtctatctc
    38461 tacaatactc gcctcagtaa gaaatccaac tccaaggcgc tgaaggcagc tgctaaggac
    38521 aatctttctg acgctgttac ctcacttgga accgccattg ccatcctagc tagtagtttt
    38581 aattatccga ttgtggataa actggttgct atcatcatca ctttctttat cttgaagact
    38641 gcctatgata tcttcatcga gtcttccttt agtctttcag atggctttga cgaccgcctg
    38701 ctcgaggact accaaaaggc tatcatggaa attcccaaaa tcagcaaggt caaatcgcaa
    38761 agaggtcgca cctacggtag caacatctac ctggatatta cactagagat gaatcctgac
    38821 ttgtctgttt ttgaaagcca tgaaatcgcg gatcaggtcg agtctatgct ggaggagcgt
    38881 tttggcgtct ttgataccga tgtccatatc gaaccagcac ctatccctga ggatgaaatt
    38941 ttagacaatg tctataaaaa attgcttatg cgtgaacaat tgattgacca aggaaaccaa
    39001 ctagaagaac tcttgactga tgattttgtc tatattcgcc aagatggaga gcagatggat
    39061 aaagaggctt ataagacaaa aaaagagtta aattctgcta tcaaggacat tcaaattact
    39121 tccatcagtc aaaaaaccaa actcatctgc tatgagttag atggtatcat ccataccagt
    39181 atctggcgtc gccacgaaac ctggcaaaat atctttcatc aagaaaccaa aaaagaatag
    39241 agaaatcctt tcatgagacg ggatttttct attcttttat actcaataaa aatcaaagtg
    39301 caaattagga agccggtcac aggctgtact tgagtcggca atgtgaagcc gacatagttt
    39361 gcactttgat tttcgaatag tcttaactat caaattcact gagatactca tagcgttcgt
    39421 atttttcaag gagtgcttca tttttctcat ccaattcttt ttggagagta gccagcttac
    39481 caaagtcaga gccgttagcc tgcatttcct cttcaatagc agcgatacgt ttttccaagg
    39541 tttcaatatc accttcaata cttgcccact cctgcttttc ttggtaggtc atgcgtttct
    39601 tgtcttctcg aaccttgacc actttttcct tttcggcctt ttgcacttga ttggccatat
    39661 ctgtttcaaa agctttttca tcaagatagt cggtgtaatg accaaagaaa ggacgaatct
    39721 tgccatcctc aaaagcgaga atcttggtcg ctaccttatc caagaaatag cggtcgtgac
    39781 tgactgttaa aacgggacct gcaaaacctt gcaagaaatt ctctaagact gtcaaagttg
    39841 caatatctag gtcattggtt ggctcgtcta aaagaagaac atttggtttt tccaaaagca
    39901 gtttgaggag ataaagacgt tttttctcac cccctgacaa tttctcaatc aaagtcccat
    39961 gcgtcgaacg tgggaagagg aattgctcca gcaactcagc gatggaagtc gtagaaccac
    40021 cactggtctt gacctcctct gccacttcct gcaggtaatt gatcacacgc ttgctttcat
    40081 ccaaaccctc aatttgttga gagaaatagg cgatgcgaac agtttcccca atcacaactt
    40141 gtcctgctgt cggctcaaga cttcctgcaa tcaggttaag tagggttgat tttccaacac
    40201 cattgtcccc aacaattcca atacggtctt tagcctgaac taagagatta aaattttgca
    40261 aaatgggctt attttcatag gcaaaggaaa catcctgaaa ctcgatgact ttcttcccaa
    40321 tccgactggt ttcaaagttc atagtcaagt ctgtctcagc actactgcct gaaacttcct
    40381 ttttcagatc atggaaacga ttgatacgag cttgttgctt ggtcgcacgt gcctgcggtt
    40441 gtctgcgcat ccaggccagt tcttgtttgt agagttgttc ttttttatga agtagagctg
    40501 catcgcgctc atcctgttct gccttaaggc gaacatagtc ctggtaattg ccctgatatt
    40561 ctgtcaagcc tgctcgctcc aactcgaaaa tccgtgttga caaagcgtct aagaaataac
    40621 gatcgtgagt gataaaaagg acggtcttct tagaattttt caaaaagagg gtcagccact
    40681 caataatcgc aatatccaga tggttggtcg gctcatccaa aagcaagagg tcgtggttgc
    40741 caagtaagac ttgtgccaac tgtacccgtc ttctcagacc acctgacaat tccccaacag
    40801 gagtagataa gtcttgaatg cccaatttgc taagaacggt cttgacctga ctctcgattt
    40861 cccaagcttg gagagagtcc atctctgcca tgacacgttc caaacgcgcc tgattgtcct
    40921 cactatagtc gagcataatc aattcatact cacgaatgag ctggatttcc ttgagttcac
    40981 tagatagaac cgtatccaaa actgtctttc tatcatcaaa atcaggatcc tgagtcaagt
    41041 aaccaatctg gtaatcattt ttagctgaaa aaggactgac atccccatca aatccagaaa
    41101 caccagaaag gacgtccaaa agggtggtct tgccagtccc attgacaccg attaaaccaa
    41161 ttctgtctaa gtcatggata ataaaggaaa tatccctaaa aacggtcttg tcaccaacgg
    41221 atttacttag tttttcaacg ataaaatcac tcattttttc tccctcaggt aagcatggat
    41281 ggcttcacga ttattctcca attctccatc gacaatggca aactcaatct ctgttaaaat
    41341 ctctcccaag tctgggcctg gctgatagcc atattccttg atcaaaatac cgccattaat
    41401 ctgaatctct ttcttgtcat ggatagtcaa gctttggtat ttttctgtga tggcttgtgg
    41461 gttgacttct tttccttgag cttgacgaag attttcagcc tgtaaaagca aatctatgtc
    41521 aaagcgataa caatctcgct tgctcaattc tccattttca cgcagagcca aaataatcag
    41581 caaatcctga acttgcttgg caaactggcg tgaggtcttc caagatttca aaaatgactg
    41641 cgcattttca atctccaaag cccatagtaa agccgcccag gcttgttcag aggattcaaa
    41701 agtaaaatca gtctccaaat caaacagtct gttgagcttg tcctggctag atgccatatc
    41761 agggagatag tcataagctt gactctcaat catggaagcc aagccccttc tccaaaatgg
    41821 agccagcaag agtttatcaa actcgacgaa ggtacgctct acagaaattt tctccaaaag
    41881 cggcgtcaag gtcttcatag ctttaaatgt ttctgactca agtgcaaaac caagactagc
    41941 ctgaaaacgg aaaccacgca taatccgtaa agcatcttcg ttgaaacgct cactagccac
    42001 tccaactgct cgcaagactt gcttttccaa atcttctaaa ccatggaaca agtcaacgat
    42061 ttctcctgtc tcatccaagg caaaggcgtt gactgtgaaa tcacggcgtt tgaggtcttc
    42121 ttctagcgat cgtacaaagg aaaccgcact gggtctgcga tagtccacat agacatcctc
    42181 tgtccgaaag gttgttacct catactcctc atccccatct aagaccaaga cggttccatg
    42241 ctcgattccg atatcggctg ttcgcggaaa aatctgcttg gtctcttctg gataagaaga
    42301 cgtcgcaata tccacatcgt ggatagggct atggagaagg gcatctcgaa cagagccccc
    42361 aacaaaataa gcctcaaagc ctgcttcttt aattttttct aatactggta aagccttctg
    42421 aaattcagaa ggcatttgcg ttaatctcat aataagtgtt ctaatccata gacaagctca
    42481 tgacgcttga caacttcttt aattcccaaa ttgactcctg tcatgaagga gatgcgatca
    42541 taggagtcat gacggagggt caacccttct ccctgattgc caaagatgac ttcctgatga
    42601 gctaccaagc ctggcaaacg aactgagtgg atgcgcatac catcaaagtc agcaccacga
    42661 gcaccagcaa tcagctcttc ctcatctgct gcgccttgct gaatggactc tcgaacctct
    42721 gccattaact cagctgtttt aatggctgtt ccactcggag catccttttt cttgtcatga
    42781 tggagctcaa taatctccac atttgggaaa tatttggcag cctgcgtcgc aaattgcatg
    42841 agtaagacag cacccaaggc aaagttaggg gcaatcaggc cacccaagtc ttgggcacga
    42901 gaaaattctt ttagctctgc aatttcttca ctcgtgaaac cagtcgttcc aactactgga
    42961 gcaaagccat tttcaagagc aaaacgtgta ttttcgtagg caacagctgg agtagtaaaa
    43021 tctacccaga catccgcttc aaaaccagct aaatcagcct tatccttgaa aacaggaata
    43081 ccctgccatt ctgactcaga ctcaaaagga tccaaaactg ctaccaagtc caagtctgga
    43141 gcagtcaaga ccatctgaca agcagcctgg cccatctttc ccttaaaacc ggcaataatt
    43201 actcgaatac tcatctctac tcctgtctaa gatacaaagt ccgtaagaac acaaagtgaa
    43261 aataggaatt ccaatcaaga agtgtctact tcttggaaga actatctttt tcacacaggg
    43321 ttccaggcgt gttcaattat caagatacaa aggaccttag ctgcccctga aaaataggga
    43381 atggcactga ctttccacga aaggcaagac aggcatcttt tttcaagagg caggtagtcc
    43441 gtgttcaatt tctaagatac aaggcatctt aactagccta gaagcgccaa ctaaatcact
    43501 ggaatataac ccagagcaat acttcctgat cctaggtgcg ttccaatgac actaccaaat
    43561 gtagcaagtg aaacatccga acccaagcca aaatcaagca aatgctgacg caattcttca
    43621 gccttttcag gagcattccc atgaatgaca atgacccggt attgacctga agccgttgtt
    43681 tccttgatga tttcaattaa gcgtttggtg gccttctttt cagtacgaac tttttcgtaa
    43741 acttcaatca taccttgatc gttaaaataa aggattggct taatgctaag caaattgccc
    43801 aaaatggcag ccccatttga aaggcgtcca ccttttacca aatgatccaa gtcatctacc
    43861 atgataaagg ctgacgtacg gctgatttga atggctagct tatcctgaat gctggcaaaa
    43921 tcatcgccct gatcacgcca attaaagacg ctttcaacca tgatgcctag gggagcactt
    43981 gtaatcaaag tgtctgggaa agcaatggtt aagccctcat agtcatcgac catatactgg
    44041 atattttggt aaaaacctga aattccagaa gataggaaaa gccccaaggc atgtgtatag
    44101 ccttgttctt tgagcgaagt taagatctca tctaacttgg caatacttgg ttgactggtc
    44161 ttaggcaatt cagaagcctg agccattttt tggtaaaatt cctcagcaga cagattgatg
    44221 ccttcgacat attcctcacc atcaatattg acaggaatat ccaagacaaa caagtcttct
    44281 ctttgcaagg tctctgcact gagataagca gaggaatctg tgaaaacagc taatttcata
    44341 ttagaactcc aaattaattc ctggtaagtc taatgcaatt tcagtcactt cgtaagtcaa
    44401 acgattgagc atgttcaaac atggacgagc caaggtttcc acctcttctt ggttcaattc
    44461 acttggttca ttgacaatac ggccatcgat atggtttact tgtgagattg ttccactaat
    44521 gacaaactta tcaaatacaa tcataaagct caagatgaca atcaaggaag tcacttgatt
    44581 ttcttggtca tgttggagca attggaaatt cacatccacc ttggtttcag gagctccatt
    44641 ttcattttcc cattcaaaat tacgcgcatc aaaatgatac tgactaacaa attcttgttc
    44701 acgtttaaga ttcatgtctt tctccatcgg ctacaatatt ataagctatt gtaccataat
    44761 tttttatttt catctagttt tctaggattt agtcaatccc aatttcagca cgaactacat
    44821 ctgtgatggt atcaacatag tagtccactt cttctgttgt aggcgcttct gccataacac
    44881 gcaagagggg ctctgttcca cttggacgaa caaggatacg gccgttcccc gccatttctt
    44941 cttccatctt ctcgatgatg gccttgatag ctggcacttc catggccttt tccttcatga
    45001 cgttttccac tcggatatta actaattttt gtggataaat cgttacttct gccgccaact
    45061 ctgataagct cttaccagtt tccttcatga ttttagtcaa ttgaactgct gataattgac
    45121 catcacctgt ggtattgtaa tccatcaaga taacgtgacc agactgttca ccaccaaggt
    45181 tgtagcctga ttttctcatt tcttcaacaa cgtagcggtc accaactgca gtaactgcct
    45241 tgttaatacc ttcgcgattc aaggccttgt ggaaaccaag gttagacata acagttgtca
    45301 caattgtatt ttgagccaat tgtccttttt cagaaaggta ttttccgatg atgtacataa
    45361 tcttgtcacc atcgacgatg tcaccattct catcaacagc aatcaagcgg tcactgtctc
    45421 catcaaaggc caaaccaata gctgacccac tttctttgac cacttcttga agggcttctg
    45481 gatgtgttga accaacatta aggttgatgt taagaccgtc tggtgtttcc ccgataaccg
    45541 tcaattgggc accaaggtct gcaaagattt gacgggcact ggtagaagct gctccattag
    45601 ctgtatccaa ggcaaccttc attccatcaa gaggagttcc agttgaaaca aggtatcctt
    45661 catacttacg caagccttct ggataatcta ccaaaattcc taagccttct gcacttggac
    45721 gaggaagagt gtcttcctca gcatctagca aggcttcaat ttctgcttct ttttcatcat
    45781 ctagtttgaa gccatcaccg ccaaagaact tgattccgtt atcaagggct gggttgtggc
    45841 tagcagaaat catgacaccg gcacttgctc cttcagtttc aaccaagtaa gctactgctg
    45901 gtgttgcaag gacaccaagt ttgtatacgt gaatccctac tgaaaggaga cctgccacca
    45961 aggccgattc cagcatttcc cctgaaatac gtgtgtcacg tcctacaaag actttcagcg
    46021 cttccgtttc atgttgacta agaacatagc ctccaaaacg tcctagttta aaggctaatt
    46081 ctggtgttag ttctaggtta gcttctccac ggactccatc agtcccaaaa tatttaccca
    46141 ttgttataaa atccttttct atttttaatt cgtttttgaa ctagttgctt tcgttgacga
    46201 agatgtctcc gatgaactgc ttgtacttga atttgatgtg cttgaacttg gtgctactgg
    46261 ttttgtagtc accttcatta ttgtatcaaa cggagtgata actgccggta agacaacacc
    46321 attgcggtcg attgcctgca aaggtactga accactgtaa ttacctgtta tacgttcgct
    46381 agttggcaag acagcgataa tcttatcaat tctatccaat gtctcttggt cactcgtaat
    46441 cgacacttct ttatctgaca ccatgacatt ttcaatttgt acccgactat caatttgact
    46501 agggtcaatc tctggtacaa tctttacctt atccttctga gccttcttac caatcttgac
    46561 tgtaattttt tgcggagtcg ccacagcggt cagcccattg ggtaaatctt caatgctcaa
    46621 aggaacttca atcgttccaa caccggcatc tgttaggtca gcagtaacct tgaatttacg
    46681 tgtactttct tgcatttcac tagctagcga taggcgattt gcaccagtca agaccactga
    46741 tacttctgaa gcaaaaccgc taataaaata cttatcacta ttatagcgta tgtcaatagg
    46801 gacatttgtt actgtattag tataggtttc cgtttttacc tgcctagcac tggtactgtt
    46861 ttgaaaattc gtcgccgtag catagacaaa taagacacaa gcaaaaaaga gtgaggatat
    46921 gatatataaa ctattttttt tcatgtttcc atcctcctag ccatcgttct ttaaaactaa
    46981 gacccacttc ctcttttgga agtaagattt cacgtaattc tgtttcaaat tcatcaagtg
    47041 ttaggttgtg cttaaacctt ccattatagg ttatcgaaat tcctcccgtt tcctctgata
    47101 cgacaaaagt caaggcatct gagacttctg ataaaccgat agccgcccgg tgtctggtcc
    47161 caaattcctt ggaaatacct gtgttttttg tcaagggcag ataggcagac gtcacagcga
    47221 tacgttcttc tttgataatc accgcaccgt catgtagggg agtgttggga ataaaaatgt
    47281 taatgagaag ttctgcagaa atcttagcat ccaaggggat tcctgtcgaa atatactcct
    47341 gcaaggtacg tacacgctga atagcaacca aggccccgat tttacgagga ctcatgtatt
    47401 caacagactt aacaaaggca cgaatcatct gttcctcagc actaataggg gcattggaaa
    47461 agaaatctgt cgctcttccc aaacgttcca aaccagtccg aatctctgga gagaagataa
    47521 caaccgccgc aataacccca taagtaataa tttgattgat taaccaagaa atcgtagtca
    47581 aaccaatcat atttgcaagg atttgagcta aaataaatac caaaactcca cgtaccaaaa
    47641 tcataatctt ggttcctgca atagcttttg taaaatggta taaaatataa gcaacaatca
    47701 aaatatcaat cagattgata gctatcgtcc atggacttgc aaacaaactg gtccaatatt
    47761 gcagattgga taattgttga aaattcatcc ctgatatcct ccctatcaaa acactttcgt
    47821 cctattatac cattttcggg catttttttc cctatcctag tccattttac attgaacaaa
    47881 aatatgataa aataaactga ctagaaaaaa caaaggagaa actatgtctc aactctatga
    47941 tattaccatt gtgggtggtg gtcctgtcgg gctttttgca gccttttatg cccacctacg
    48001 ccaagccaag gttcaaatca tcgactctct tccccagcta ggtggacaac ctgctattct
    48061 ctaccctgaa aaggaaatcc tagacgtacc aggcttccca aacctgactg gagaagagtt
    48121 gactaaccgc ttgattgaac agctaaatgg atttgatacc cctattcatc tcaatgaaac
    48181 ggttcttgag attgacaaac aagaagaaga atttgccatc acaacttcta aaggaagtca
    48241 cctgactaaa acagttatca tcgctatggg tggcggtgcc ttcaaaccac gtccgctgga
    48301 acttgaaggg gttgagggct atgaaaatat ccactaccac gtttctaaca ttcagcaata
    48361 cgctggtaag aaagtgacga ttcttggtgg gggagactcg gctgtggatt gggctttggc
    48421 ttttgaaaaa atcgcaccaa ctacccttgt tcaccgcaga gataatttcc gtgccttgga
    48481 acacagtgtt caagccttgc aagaatcatc tgtaaccatc aagacaccat tcgcccctgg
    48541 ccaactcctt ggaaatggaa aaacacttga taaacttgaa atcacaaaag tcaaatctga
    48601 tgaaactgaa accattgacc tagaccacct ctttgtcaac tatggtttca aatcttctgt
    48661 cggtaacctt aaaaactggg ggctcgacct caaccgtcac aagattatcg tcaacagcaa
    48721 acaagaatcc agccaagcag gtatctatgc tatcggtgac tgctgctact atgacggaaa
    48781 aattgatctg attgcgacag gcctcggaga agctccaact gctgtcaaca acgctatcaa
    48841 ctacattgac cctgaacaaa aagtacaacc aaaacactct accagtttat aaaaaagaac
    48901 cacgagtcac ataggattcg tggttttata attcatccgc tatcttattg atttttctga
    48961 gtctgtgatt gacaccactt ttggtcagag gggtgctgag actatctgct aactgctgga
    49021 tagagtagtc tgggtgctga atcctcagtt gcgccacttc ctgcaaatct actggcaaat
    49081 tttctaagcc catgatatct ttgattttac tgatattgtt aatggtcttc atgctggcag
    49141 aaactgtccg agcgatatta gctgtctcgg cattattagc ccgattgagg tcgttacggg
    49201 tttctcgcaa aatcttaacc cgctcaaaat catcacgtgc ctgcatggct ccgattacta
    49261 tcaagaagtc cataatgtct tctgctcgct ggagataggt cacagccccc ttcttgcgct
    49321 caagcacctt ggcatccagt aaaaactgtt ggagaaggga ggcaattcct tgcgcgtggt
    49381 ccagataaac agaactgatt tccaactggt acttgcctga ctcagggtca cgaatgctcc
    49441 catttgccaa gaaagcgcca cagagatagg cacgacctgc ttcctcatcc gataaaatcg
    49501 cctcatcaat acctgtttcc aggccaaaga aagagtctgc caagtgcaaa tcacttaaca
    49561 aatcctgcac cttttcatct gtaaaaacgg tatagacgcg attcttgcga agattgctac
    49621 gttggtggtg acgaatttca gatttgattt catagaaatg aagaaaggac tcatagaggt
    49681 gacgggccag tttggcattt tctgtcacaa ctgacaaagt caagcccgaa gtcgagagac
    49741 cgatgctacc agacattttg ataatggcag ataattcatg ccagctcaga tggtgttggc
    49801 ccaggatttc ttcttttact gctactgtga aactcatttt ttcacctgta taatgcgcat
    49861 caactcgtcc acaatcaaat ctccatcgtg gaaggcaccg ccattttcca gacgaaggaa
    49921 gttagatgaa atcacgcgtg aaacttgctt acaaagacct acaaaatcgt gttccacttg
    49981 cactaagtat tcatcaaaac ggttggaatt catgtattcc tgaggcactt tttcaatatt
    50041 caccaagaca gtgtcgataa aagggcgacc aaggtgacga tgcaagactt ccacgtggtc
    50101 gctatctgta aagtgttccg tctccccacg ttgggtcatg atattgcaga cataggcaat
    50161 ttctgccttg gtttccaaaa gagcccgccc aatttcctta atcacgatat tgggcaaaat
    50221 agaggtaaag agggaacctg gccctaggac aatcatgtca ctttcaagga tggtctgcac
    50281 tactcgacgg ctggccagag gcgtatcatc gtttagggca ttggtcacat agacattgtc
    50341 aattatgcct cgatggtcta caatatgact ctctccagcc acttctatcc catcctgaaa
    50401 gactgcatga agggtcaaag gatggtcact ggaaggataa attttccctg ttgtatggaa
    50461 aaatttgctc aataactgca tggcattata ggttgaaccc tgcatttctg acaagccagc
    50521 aatgatgaga tttcccaatg gatggccagc aaaggctccg gcatcctcag agaaccgata
    50581 ctgaaagacc ttctcataaa acttaggcat atccgacatg gccacaagga cattacgaag
    50641 atcacctggc ggtgtcaact gttgcatatt ttttcggagt tcacctgaag aaccaccatc
    50701 atctgccacc gtcacgatag ctgcgatttc cacatctttt tcccgcagac tttttagaat
    50761 gacgggaatt ccagtccctc caccaatcac cgttatcttt ggttttctca tgaacggttt
    50821 accgtttcct ttctgcggtc tttgtcgcga tgcccttcat taacagacca attcttggat
    50881 aagtcctgca ccaagcgttt agcaaatgcc acactacggt gttgtccacc cgtacatccc
    50941 atggcaatgg tcaaaacgga cttaccttcc ttttggtaac ttggcagaat cggctcaatc
    51001 aaggccaata aatgttgata aaagtcttct gactcaggat ggttcatgac ataatcataa
    51061 acaggttcat ccacacccgt ttggtttctc agttctagta aataataggg atttggcaag
    51121 aaacggacat caaagaccaa gtccgcatca atcgggattc catacttaaa tccgaaagac
    51181 atgacttcga tacggaaaga ctgggcttgt tcttggtctg aaaactgctc tgcaagggtt
    51241 ttgcgcagct cacgtggagt gagttcagtc gtatccacca cattttggct catatttttc
    51301 aaaggtgcca agagttcacg ttccaacttg attccatcta aaatacgacc gtctgctgct
    51361 agtgggtgac tccgtctggt ttccttgtaa cgagcgacca attccttatc agccgcatcc
    51421 aaaaagagga ttttgaaatc caaaccatct tgattttcca actcatccaa aacagcttga
    51481 atctctgaaa agaaagaacg gctacgcata tccactacca aggccaactt aggattgtct
    51541 tccttaattt caaccagctg caaaaactta ggcaagagag ctggcggcat attatcaatg
    51601 gtgaaataac ctagatcctc gaaggactga atggctacag ttttccctgc gccactcatc
    51661 cctgtcacaa tcaccaagtg aagttgtttc tttgtcatct ttttctcctt atatcaaaag
    51721 aagtttggca acaccaaact tcaactagct tatccaatct ctgcgatgac ttcaatttcg
    51781 acttttacat cacgaggaag acgagctacc tccacagctg aacgagctgg gaattcctct
    51841 ttgaaggccg tttggtaaac ctcattaaaa ggaacaaagt cgttcatatc gctcaagaaa
    51901 caagttgttt tgacaacatg gtcaaagtct gttcctgctt ctgccaaaat agcaccgatg
    51961 tttttcaaga cttgctctgt ctgttcttgg atattctctc ctacaatttc cccagtttca
    52021 ggggataggg gaacttgacc gctagcaaac aaaaggttgc caacgatttt tccttgaaca
    52081 tagggcccga tagcctttgg ggccttatct gtatgaattg tttttgccat tttcttttcc
    52141 tcacaatttt tctaagattg catcccaagc ctcatccatc cctgccttgc tgacagatga
    52201 aaagaggatg aaatcgtcac ttgggtcaaa gtttaatttc tttttgattg ctgattcatg
    52261 cttgttccat ttaccacgag gaatcttgtc cgccttggtc gccacaatga tgactggaat
    52321 ctcataatac ttgagaaatt cgtacatctg cacatcatct gctgacgggt catgacgaag
    52381 gtcaactaga ctgacaaccg cacggagatt ttcccgagtc gttaagtact cctcaatcat
    52441 gcacccccac ttttcacgtt cctttttaga aacacgagca tagccataac caggcacatc
    52501 cacaaagcgc atcttgtcat caatgttaaa aaagttcagg agctgggttt taccaggttt
    52561 tcctgatgta cgagcgagat tcttacggtt caacatagtg ttgataaagc tggatttacc
    52621 aacatttgaa cgccctgcta gggcaatctc tggcagttca tcctgcggat agtgggactt
    52681 attagctgca ctgagcaaga tttcagcatt gtgtgtatta agttccatag tcacctctag
    52741 gctgtttcta ggatcggttt atccgttcca tcgacagttt ctttagtgat gcgaaccaat
    52801 ttcacatttt cctgactcgg cacctcaaac ataacatcta gcatggtttc ttcgatgatg
    52861 gagcgaagtc cacgcgcccc tgtcttccgt tcgattgctt tattagcaat ctcttgaagg
    52921 gcttcgtcgt caaattccaa ctcaacatca tcataagaaa gcaaggtttg gtattgtttc
    52981 accaaggcat ttcttggctc tttcaagatg cgaaccaagt catcaacggt caattgctca
    53041 agagccgcaa aaacaggcaa gcgtccaatc aactcaggga taataccaaa tttttgaatg
    53101 tcttcagcga tgatttcttg catgtatgag ctgttttcgt caatcgcctt attgttttga
    53161 ccaaatccga tgactttttc acccagacgt tgtttgacaa tttcttcaat accatcaaaa
    53221 gcaccaccca cgatgaagag gatatttttt gtatccactt gaatcatctc ttgttgtgga
    53281 tgtttgcgtc caccttgagg cggtacgcta gcaacagttc cctcaataat cttgagaagg
    53341 gcttgttgca ccccttcacc agaaacatca cgtgtgatag acacattctc actcttcttg
    53401 gcaatcttgt caatttcatc cacatagata atgccacgct ctgcacgttc gatgttaaag
    53461 tcagcaacct gcaagagttt gaggagtata ttttccacat cctcacccac ataaccagcc
    53521 tccgtcagag ctgtcgcatc cgcaatagca aaaggtacat tcaagctctt agccaaggtc
    53581 tgggcaagga aagttttccc tgaaccagtt gggccaatca tcaaaatgtt tgacttctgc
    53641 aaatccacat cttctgactc ttcgcgtgta tcgtggaaat tgatgcgttt gtagtggtta
    53701 taaaccgcca ctgccaaggc acgcttggca cgatcttgac caattacata gtggttcaag
    53761 atatggagga gttcaattgg ttttggcacc tcagacaagt ctgccaagac ttcctcaacc
    53821 aattcttctc gaatgatttc ctgagctaac tccacgcatt cattacaaat aaaagcattg
    53881 ttgccagcaa ttattttttg tacttcttct tggtttttgc cacaaaatga gcaataaacc
    53941 atcatatcat tttttctatt tgtagacatg atttccttcc attctatact gtcattctat
    54001 ctaaaataag gtcatgtaaa aagcatgaat actattgacc agattggtaa aggcatttaa
    54061 ccaaaggagg atagaaagcc cgtaacgctt tttacgaaaa gcttgtgctc ctgccagaaa
    54121 gcagatgaaa cacagaaaag ccgtgaatag accaaataaa ctccgttcca ttaaacttcc
    54181 tttctcttgc ggtattggat ggtaaaatca taaggattct tctcatcttt ggcgtaaaat
    54241 ttgcttgaaa ctgtctcaaa aagagacaag tcaagctctt cagggaaata ggtatctcct
    54301 tccacccgag catgaatgtg agtgacaatc acttcatcaa ggtaagcttc aaaagcctga
    54361 aaaatttgct tcccaccgat aatgtagaga ttcttttctt gagcctgata ccagtcaaga
    54421 acagactgga cgtcctgaaa agtagcaacc ccatctatct tttcttccgg attacgcgtc
    54481 aaaatcaagg tttcccgttt tggaagcaag cgacgcccca tcccatcaaa ggtcacacgc
    54541 cccatcaaga tagcatgatt cagagttgtt tctttaaagt gctgcaattc tgctggcaaa
    54601 tgccaaggca gacgattttc cttaccaatc acaccctctt catcctgggc ccaaatagct
    54661 acgattttct tagtcatgct tccatccttt tcactgatag tactatttta tcaaaaaact
    54721 caaaaaaaga ctggtttgga atagcttaca aaatagaaaa aatctgtaag aaatttccta
    54781 cagatttatc tatgtttcct tatttcttac aaaccaggtg cttgtccaag ttcggctgca
    54841 agcatccaaa ttgttttatc tgtttcagtt ttagcgcctg caaagatacc gtttgttaca
    54901 tcgtcacctt cttcatcagt gacatccaaa cctttttgga aaagttctga caagtaacgg
    54961 tagataacaa gaacacgttc caagctttct tcaacattac ggtattcacc agcttcttct
    55021 tcgatttcac tattttgaag gaactctgtc aatgtagaga atgggcttcc accgagtgta
    55081 atcaagcgtt cgctgatttc atccaattga ccgtcaagag cttccatgta ctcatccatt
    55141 tttggatgcc atacaaggaa accacgacca tgcatatacc agtgcacttg gtgcaaagca
    55201 acgtgagcta catacaaatc agcaacagct tggttcaaga cttcctttgt ttttgccaat
    55261 gctactggcg ctgcttttgt caatgatgtt acgtctttta ctgcttcttt tttcaattct
    55321 accattttct ttacctcatt cattattttt tgtaaccact tcttaatgat tactacctta
    55381 gtatactact aaggaaaacc aatagcaaga caaagaactt atatgagaaa agttgcaata
    55441 gactgataat ttaagaattc tttagaagac aaaaagaggg ttggatgctt atagtcaatg
    55501 gaaatccatc agcaaactag gaaactaaac ccagcttgac caaagcacaa gttttgaggt
    55561 cgcaggtaga actgaccaag ctgatgtggt ttgaagaaat tccccaatac tataatagat
    55621 tgaaataaga tgaaaccaag tcgattagga aaggtaaatg aatttctaaa atgttttacc
    55681 aatcacaagg tctttgtcta tattcaatct actatataag cttcatttcc gagcaagatc
    55741 ttgaatttac tcgaggatga actatcataa aacaaagaaa aagagggtgc tactatcaca
    55801 tccctctttc aaatcatcgc ttaataccaa acgctgacat ctacgcgccc ttggattcct
    55861 ttcatgtatt cagaagaggt atattgccaa cctttttctc ctgaataata agggttttcc
    55921 cattctaaag cattcgtata ggccgctacc cagtttacat gttttaaaat atctgggtgt
    55981 tttaaacgcg tctgtaataa actacgatag ctatagacat acacattttg ataacccgcc
    56041 tgcttcatcg tgtccatgta cttgttgatg attttaaccc aagtgcctgt atcacttgga
    56101 gctctcttgc tcttatttac atattcccag ttctcaacat cataatagat agggtaagac
    56161 aggttcatat tgtatttctt tataagttca atggtctgtt tagcgtcatt ctcagcatcg
    56221 gtctcatttt cagcataggt atagagatag acaccataag gaattcccag acggtttaac
    56281 tccttaatgt tatgcgccaa ttccttgtct tctttaccgc tataacctag acgaacaatg
    56341 acaccatcca cctcgttctc atcaataacc tttttccaat cattgatacg accattgtgc
    56401 tcactaatat caatgacttt cttagcatgt tcggttccca cttgttcttc tctattatta
    56461 aagaaatagc gtttaccatc tctgtgaacc cagccgacat tcaaatcttt cttttctttg
    56521 agctcaccag aggccgcaaa gatatagcga gcaccatcca taatcacttc gtcagttgct
    56581 atggcaccac ttccagtcaa atagtagttg ccttgccact cattccgagc catatagccc
    56641 cacttcttga agtagtacca cttatttcca atcaattgcc attcttgatg agcataagcc
    56701 ccatctgact tgagataaaa ccaactcttg taattactgt catagattca ctcgttttgg
    56761 gccatatatc cacctgattt caggtagtaa tttccatgcc attcattctg cgagtaacga
    56821 ccatctgaat taatataaaa ccaaacctta tagtagttgt caaaaatcca ttcactttga
    56881 gctttagaac catcatcctt tacataataa tccccatccc agtgggcagc agcattagtc
    56941 tgtacttctg cgctcgtttg cgttttatta gaagactgat tttgctttga actacttgaa
    57001 gctgtcgttg tatcctgcga agtttttgct acttcagttt catttgcagc gacatgacta
    57061 gttgccaagc ctagtaaaca gatacttgct aatccaattt ttgttttcaa tctttcctct
    57121 cctataaaaa atgtaacaga catctgaatg ctgttccacc tagcttttgc tacttactga
    57181 ttattttaca aagtcaagca aagccaagaa gctttcagct tcaagtgacg caccacctac
    57241 aagggcaccg tcaacgtctg ggcaagccat gtatgaagca acattttcag gtttaacaga
    57301 accaccgtat tgaacacgaa ctttgtctgc gacttcttga ccaaagtcag cagctacaac
    57361 gtcacgaaca actttacaca ttttttgtgc atcgtcttgt gaagctgatt taccagtacc
    57421 gatagcccag attggctcat aagcgataac tgaggcagca acttgttcag cagtcaatcc
    57481 agccaatgca gcagatactt gagcacctac gaattcagca gctttaccag cttcgtaagt
    57541 ttcaagtgat tcaccacaac agatgattgg aagcataccg ttcgcaaaga ttgcttttgc
    57601 ttttttgttg atatcttcgt cagtttcatg gaagtagtca cggcgttctg agtgaccgat
    57661 aacaacgtag tcagtaccga tttctttcaa aacttgtggg ctagtttcac cagtgaaagc
    57721 acctgcattt tcaaagtagc agttttgagc agcaacttta aagtttgagc cttttgcaac
    57781 agcaagaaca gttgtcaaat caagagctgg agcagcgata cctgcttcaa caagatctga
    57841 tgaaggaagt tttgatgcaa ctgcttcaac gaatgcttta gcttcttctg gatttttgtt
    57901 cattttccag ttaccagcga taaatggttt acgtgacatt tcacatacct ctttttcaat
    57961 ttattttcta tttattctat cacaattata cacagcttgc aaatcttact cggatttcaa
    58021 gcctgcttgc atggattaat ccttccagag atccatggca tttctgaaat ctgcagatac
    58081 ctgtgtcaac tgaggattgc ttgcttctct ttctgctctc ttggcctcaa tttgagccac
    58141 actcttgatt ccttcatggc gccagtttct caaaatcgcc tgaatgtact tccagtttgg
    58201 ttttccattc aaaacagctt cacgaagagc ctccttaatc aagtcagcac tggttccatc
    58261 ttcctttagt gtcttggtca aatcctcaat ctcaaaaggc gtcaacaatc gtcccaactc
    58321 ctgctggaag gtttccacca aatccttgag ctggttttga ggtgttagct ggtctgaact
    58381 tgaatgaact gctccaaaca ggtcatccaa acgttccaag gccaaactag catcaaagag
    58441 caattcaatt tcgccattta attcgatagt acgatactgg agcagtcccc tttccgtcag
    58501 attagaaatg gactggttga catccgaaat ttccttgcca atcctttcag caatctggct
    58561 tggcgacatt tcttctaagc ctgtcgtatt ttgcaaatag aaaaattgcc aaaccagaaa
    58621 atcgtcgcta gaaggaaaga gttccttaaa atgcaagagc agggcactcg gtaaaaccaa
    58681 ggtacctgat ttaaaagcgt ctaaatatgt cataattcct cttataaata cccatatgca
    58741 gatgcatcat cttctatctt tatccaatca aaaggcgtct cctgatagac cgcatggttt
    58801 acccaattac tgaaaaagag ggctgcagat gaagaccaac aaagacaagg tacctgatta
    58861 acatcatcat ctttaaagta attttctgga atatgtgggt cgaaacctgc atcacgatct
    58921 cgaaaatact cttttgccaa ggtatcacgg tcatactcca aatgaccaaa actataaatt
    58981 tctcgtaaat cacgactggc caaaatagaa accccaacct gaggtccttc tgataaaatc
    59041 tcgagattgg tcttgtttaa gacctcttcc ttagaaatct ccgtgtgccg tgaatgaggg
    59101 gatacatagc tatcatcaaa gcctctaaat agaaggtgac cctcttttag ggtgtcctga
    59161 ggataaatac ctgatagctt actgtccatc tggtattttt ctacaccata gcgcagataa
    59221 agcccagcct gagcccccca acagatatga agggtcgaat agacatgagt cttagaccac
    59281 tcaagcatct gtctaaattc ctcccaatag tccacttcct caaatggtaa atgctcaact
    59341 ggagcacccg tgatgatcat cccatcaaaa tactcatcct tgacttcagg aaaagtttta
    59401 tagaaggtct ccatgtgctc tgaacgagtt gttttagaac ggtggctctc catatagaga
    59461 aaatcaatat ccagttgtag gggtgtatta gccaagtggc gcaacaactg ggtctctgtg
    59521 accattttct gtggcatgag atttaaaatt aaaatcttca aaggacggat atcttggtgg
    59581 gcagcacgtt gatcatccat gacaaagata ttctctgtcc gtaaaatctc aacagctggc
    59641 aattttttat caattcgaat cggcataacc ctctcctaac tgtactcttt caggaataat
    59701 tgcatatgtt tgaagacaaa tctcaaacac ttagtccttt tattatactg taagaagata
    59761 tagttttcaa ttatagtttt tctctaacta gttatagtct atttttatat cctagtgtag
    59821 agaaaacagc cctagggact gttttcatta at
//
LOCUS       DAVKAU010000007        56614 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVKAU010000007 DAVKAU010000000
VERSION     DAVKAU010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.007"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            3..75
                     /locus_tag="VWX48_000489"
     tRNA            3..75
                     /locus_tag="VWX48_000489"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36..38,aa:Val,seq:tac)
     gene            81..151
                     /locus_tag="VWX48_000490"
     tRNA            81..151
                     /locus_tag="VWX48_000490"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:113..115,aa:Gly,seq:tcc)
     gene            186..259
                     /locus_tag="VWX48_000491"
     tRNA            186..259
                     /locus_tag="VWX48_000491"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:220..222,aa:Ile,seq:gat)
     gene            342..431
                     /locus_tag="VWX48_000492"
     tRNA            342..431
                     /locus_tag="VWX48_000492"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:378..380,aa:Ser,seq:tga)
     gene            442..515
                     /locus_tag="VWX48_000493"
     tRNA            442..515
                     /locus_tag="VWX48_000493"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:476..478,aa:Met,seq:cat)
     gene            519..591
                     /locus_tag="VWX48_000494"
     tRNA            519..591
                     /locus_tag="VWX48_000494"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:552..554,aa:Phe,seq:gaa)
     gene            604..684
                     /locus_tag="VWX48_000495"
     tRNA            604..684
                     /locus_tag="VWX48_000495"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:638..640,aa:Tyr,seq:gta)
     gene            689..759
                     /locus_tag="VWX48_000496"
     tRNA            689..759
                     /locus_tag="VWX48_000496"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:721..723,aa:Trp,seq:cca)
     gene            774..846
                     /locus_tag="VWX48_000497"
     tRNA            774..846
                     /locus_tag="VWX48_000497"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:807..809,aa:His,seq:gtg)
     gene            860..931
                     /locus_tag="VWX48_000498"
     tRNA            860..931
                     /locus_tag="VWX48_000498"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:892..894,aa:Gln,seq:ttg)
     gene            941..1024
                     /locus_tag="VWX48_000499"
     tRNA            941..1024
                     /locus_tag="VWX48_000499"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:975..977,aa:Leu,seq:caa)
     gene            1131..2408
                     /locus_tag="VWX48_000500"
     CDS             1131..2408
                     /locus_tag="VWX48_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU9171174.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2484..3968
                     /locus_tag="VWX48_000501"
     CDS             2484..3968
                     /locus_tag="VWX48_000501"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU9171175.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNTLNTQGQYELTDFDVEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            4029..5309
                     /locus_tag="VWX48_000502"
     CDS             4029..5309
                     /locus_tag="VWX48_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9171176.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMILKG"
     gene            5313..5936
                     /locus_tag="VWX48_000503"
     CDS             5313..5936
                     /locus_tag="VWX48_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9171177.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFEAER"
     gene            6098..7240
                     /locus_tag="VWX48_000504"
     CDS             6098..7240
                     /locus_tag="VWX48_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9171178.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAALAVEATTTS
                     SEAKEVASSNGATAAVSTYQSEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7563..7988
                     /locus_tag="VWX48_000505"
     CDS             7563..7988
                     /locus_tag="VWX48_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU9171179.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            7999..8358
                     /locus_tag="VWX48_000506"
     CDS             7999..8358
                     /locus_tag="VWX48_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU9171180.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8465..9082
                     /locus_tag="VWX48_000507"
                     /pseudo
     CDS             8465..9082
                     /locus_tag="VWX48_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9109..9966)
                     /locus_tag="VWX48_000508"
     CDS             complement(9109..9966)
                     /locus_tag="VWX48_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU9171181.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCHSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10096..11238
                     /gene="tgt"
                     /locus_tag="VWX48_000509"
     CDS             10096..11238
                     /gene="tgt"
                     /locus_tag="VWX48_000509"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU9171182.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11339..13156
                     /locus_tag="VWX48_000510"
     CDS             11339..13156
                     /locus_tag="VWX48_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU9171183.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13309..14460
                     /gene="nagA"
                     /locus_tag="VWX48_000511"
     CDS             13309..14460
                     /gene="nagA"
                     /locus_tag="VWX48_000511"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU9171184.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14623..15681
                     /locus_tag="VWX48_000512"
     CDS             14623..15681
                     /locus_tag="VWX48_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU9171185.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15832..16197
                     /locus_tag="VWX48_000513"
     CDS             15832..16197
                     /locus_tag="VWX48_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU9171186.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16273..17214
                     /locus_tag="VWX48_000514"
     CDS             16273..17214
                     /locus_tag="VWX48_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU9171187.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17162..18178
                     /locus_tag="VWX48_000515"
     CDS             17162..18178
                     /locus_tag="VWX48_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU9171188.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18180..18506
                     /gene="comGC"
                     /locus_tag="VWX48_000516"
     CDS             18180..18506
                     /gene="comGC"
                     /locus_tag="VWX48_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU9171189.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVND"
     gene            18499..18903
                     /locus_tag="VWX48_000517"
     CDS             18499..18903
                     /locus_tag="VWX48_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU9171190.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            18908..19168
                     /locus_tag="VWX48_000518"
     CDS             18908..19168
                     /locus_tag="VWX48_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171191.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19131..19592
                     /locus_tag="VWX48_000519"
     CDS             19131..19592
                     /locus_tag="VWX48_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9171192.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            19570..19983
                     /locus_tag="VWX48_000520"
     CDS             19570..19983
                     /locus_tag="VWX48_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9171193.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20120..20714
                     /locus_tag="VWX48_000521"
                     /pseudo
     CDS             20120..20714
                     /locus_tag="VWX48_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20775..21728
                     /locus_tag="VWX48_000522"
     CDS             20775..21728
                     /locus_tag="VWX48_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9171194.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21779..22969
                     /locus_tag="VWX48_000523"
     CDS             21779..22969
                     /locus_tag="VWX48_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU9171195.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23118..23489
                     /gene="rnpA"
                     /locus_tag="VWX48_000524"
     CDS             23118..23489
                     /gene="rnpA"
                     /locus_tag="VWX48_000524"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU9171196.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYQEGNGSEKETKVD"
     gene            23464..24288
                     /locus_tag="VWX48_000525"
     CDS             23464..24288
                     /locus_tag="VWX48_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9171197.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNEVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGQFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24307..25293
                     /locus_tag="VWX48_000526"
     CDS             24307..25293
                     /locus_tag="VWX48_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU9171198.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25344..25967
                     /locus_tag="VWX48_000527"
     CDS             25344..25967
                     /locus_tag="VWX48_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU9171199.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26098..27555
                     /locus_tag="VWX48_000528"
     CDS             26098..27555
                     /locus_tag="VWX48_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9171200.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27578..27859
                     /locus_tag="VWX48_000529"
     CDS             27578..27859
                     /locus_tag="VWX48_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9171201.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            27936..28421
                     /locus_tag="VWX48_000530"
     CDS             27936..28421
                     /locus_tag="VWX48_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9171202.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELDDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28438..29103
                     /locus_tag="VWX48_000531"
     CDS             28438..29103
                     /locus_tag="VWX48_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU9171203.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIRR
                     IWG"
     gene            29107..29970
                     /locus_tag="VWX48_000532"
     CDS             29107..29970
                     /locus_tag="VWX48_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU9171204.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIATLHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            29972..30676
                     /locus_tag="VWX48_000533"
     CDS             29972..30676
                     /locus_tag="VWX48_000533"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU9171205.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDFPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30853..32526
                     /locus_tag="VWX48_000534"
     CDS             30853..32526
                     /locus_tag="VWX48_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9171206.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTLSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTFINQEIVVQAFLEDI"
     gene            32638..33729
                     /gene="ulaG"
                     /locus_tag="VWX48_000535"
     CDS             32638..33729
                     /gene="ulaG"
                     /locus_tag="VWX48_000535"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU9171207.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33843..35825
                     /gene="tkt"
                     /locus_tag="VWX48_000536"
     CDS             33843..35825
                     /gene="tkt"
                     /locus_tag="VWX48_000536"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9171208.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVAAAKEL
                     ASKGEKVRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLKQS"
     gene            35936..36235
                     /gene="yajC"
                     /locus_tag="VWX48_000537"
     CDS             35936..36235
                     /gene="yajC"
                     /locus_tag="VWX48_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9171209.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36282..36710
                     /locus_tag="VWX48_000538"
     CDS             36282..36710
                     /locus_tag="VWX48_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU9171210.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36712..37122
                     /locus_tag="VWX48_000539"
     CDS             36712..37122
                     /locus_tag="VWX48_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171211.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37422..40073
                     /gene="adhE"
                     /locus_tag="VWX48_000540"
                     /gene_synonym="adhC"
     CDS             37422..40073
                     /gene="adhE"
                     /locus_tag="VWX48_000540"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU9171212.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(40940..41248)
                     /locus_tag="VWX48_000541"
     CDS             complement(40940..41248)
                     /locus_tag="VWX48_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9171213.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(41245..41553)
                     /locus_tag="VWX48_000542"
     CDS             complement(41245..41553)
                     /locus_tag="VWX48_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9171214.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALEWIGEIR
                     "
     gene            complement(41558..42853)
                     /locus_tag="VWX48_000543"
     CDS             complement(41558..42853)
                     /locus_tag="VWX48_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9171215.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(42871..44280)
                     /locus_tag="VWX48_000544"
     CDS             complement(42871..44280)
                     /locus_tag="VWX48_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9171216.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTALTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            44438..45166
                     /locus_tag="VWX48_000545"
     CDS             44438..45166
                     /locus_tag="VWX48_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9171217.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45626..45820
                     /locus_tag="VWX48_000546"
     CDS             45626..45820
                     /locus_tag="VWX48_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9171218.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(46186..47496)
                     /locus_tag="VWX48_000547"
     CDS             complement(46186..47496)
                     /locus_tag="VWX48_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU9171219.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47733..48605
                     /locus_tag="VWX48_000548"
     CDS             47733..48605
                     /locus_tag="VWX48_000548"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU9171220.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQRAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            48736..49582
                     /locus_tag="VWX48_000549"
                     /pseudo
     CDS             48736..49582
                     /locus_tag="VWX48_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            49785..50618
                     /locus_tag="VWX48_000550"
                     /pseudo
     CDS             49785..50618
                     /locus_tag="VWX48_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857688.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            50795..51802
                     /gene="gap"
                     /locus_tag="VWX48_000551"
     CDS             50795..51802
                     /gene="gap"
                     /locus_tag="VWX48_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU9171221.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(51870..52706)
                     /locus_tag="VWX48_000552"
     CDS             complement(51870..52706)
                     /locus_tag="VWX48_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9171222.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            52832..55027
                     /locus_tag="VWX48_000553"
     CDS             52832..55027
                     /locus_tag="VWX48_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9171223.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            55080..55232
                     /gene="rpmG"
                     /locus_tag="VWX48_000554"
     CDS             55080..55232
                     /gene="rpmG"
                     /locus_tag="VWX48_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9171224.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            55242..55418
                     /gene="secE"
                     /locus_tag="VWX48_000555"
     CDS             55242..55418
                     /gene="secE"
                     /locus_tag="VWX48_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU9171225.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            55473..56009
                     /gene="nusG"
                     /locus_tag="VWX48_000556"
     CDS             55473..56009
                     /gene="nusG"
                     /locus_tag="VWX48_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU9171226.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            56131..56610
                     /locus_tag="VWX48_000557"
     CDS             56131..56610
                     /locus_tag="VWX48_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU9171227.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRKYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT        17337 a        10077 c        12393 g        16807 t
ORIGIN      
        1 tagggagttt agctcagctg ggagagcatc tgccttacaa gcagagggtc agcggttcga
       61 tcccgttaac tcccatttta gcgggtgtag tttagtggta aaactacagc cttccaagct
      121 gttgtcgcga gttcgattct cgtcacccgc tttgaacttt gttctttgta ccaagttttt
      181 aacttgggcg cgtagctcag gtggttagag cgcacgcctg ataagcgtga ggtcggtggt
      241 tcgagtccac tcgtgcccat agtgtttagt ccattactag gggattggaa tattatctgt
      301 tcactaagag gacacgggct tgttcccgta taaactattt tggaggatta cccaagtccg
      361 gctgaaggga acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg gttcgaatcc
      421 cacatcctcc ttttatatta acgcgggatg gagcagcacg gtagctcgtc gggctcataa
      481 cccgaaggtc gtaggttcaa atcctgctcc cgcaataagg ctcggtagct cagttggtag
      541 agcaatggat tgaagctcca tgtgtcggcg gttcgattcc gtctcgcgcc atttatatat
      601 tttggaaggg tagcgaagag gctaaacgcg gcggactgta aatccgctcc ttcgggttcg
      661 ggggttcgaa tccctcccct tccattttac gggcatagtt taaaggtaga actaaggtct
      721 ccaaaacctt cagtgtgggt tcaattccta ctgcccgtgt taatagaatt atggcgggtg
      781 tggtgaagtg gttaacacac cagattgtgg ctctggcatg cgtgggttcg atccccatca
      841 ctcgcctatt ttatattatt ggggtatagc caagcggtaa ggcaagggac tttgactccc
      901 tcatgcgttg gttcgaatcc agctacccca gttactattt gccggcgtgg cggaattggc
      961 agacgcgctg gactcaaaat ccagtgtccg caaggacgtg ccggttcgac cccggccgcc
     1021 ggtatagtat agtgttagga acgttgttat tcttcgttcc ttttttatat tatttttggt
     1081 ataattatag ttattcaaat tttatttaga ttgagaaagt gtagggtagt atgtcttgtt
     1141 ctatcgattt attaaaacat cggtatttga aaaatattaa agaaaatcct gaattgtttg
     1201 tcggaattga gttggagtat cctgttgcaa gtttagaagg ggatgctaca gatgttgaag
     1261 ttataaagga tctatttcat tatttagttt ctactttgga tctcaccgta gcaaaggtag
     1321 atgattttgg caatctgatt cagttagtag atccgataag tcaggatgct attttgtttg
     1381 aagtttccta tacaacgatt gagtttgcat ttggtaaggc tgaaacgatt caagaggtcg
     1441 aaaatcgttt caataattat atgaatgtaa ttcagagaaa gttagctgaa tcaaatcatg
     1501 ctattgttgg ctgtggtatc catcccaact gggataaaaa tgagaattgt ccagtggctt
     1561 atccacgcta tcagatgttg atggattatt tgaatttgag tagaaatatt attaaatcag
     1621 atttacatca tttccctgaa tatggtactt ttatctgtgg gagccaggtt cagctggata
     1681 tttcaaaaac taactactta cgggtgatta atgcttttac tcaaattgaa gcggctaagg
     1741 cttatttatt tgcaaactct gagttttcgg gtgcggattg ggatacgaaa atttcaaggg
     1801 atattttctg ggaagaatct atgcatggta tctatccaga gaatgttggg gtcaatgcta
     1861 gactccttaa tgatgaagct gatttttttg actatctaaa tcattctgcg atttttactg
     1921 cggaacgtga tgggcagacc tattattttt atcctattca ggctggggac tatttggcta
     1981 cgcctgaaat ccaagcattt gctctgaatg gggatgaggt tattatttac ccccaagaga
     2041 aggattttga aactcatcgt agttaccagt accaagactt aacgactcga ggaacagttg
     2101 agtttcgtag tgtgtgtaca cagccacttg ataggacttt tgcttctgca gcttttcact
     2161 tgggattatt ggttaattta gacaagttag aagcttactt agaaacagca cctttcttta
     2221 aagtatttgg ttatgattac aagtttttaa ggagacaatt ttctaagaaa aatcttacag
     2281 atgaggaaga aactacgatt attgaatttt ccaaagactt actcctacta gctgaggagg
     2341 gactagtggt gagaaataag gaagaaatga cctatttaca gcctttgaga gaagaattga
     2401 gcctataatt tctcttataa agggagaatt ttctgaaaaa tcatgatata atggacgaga
     2461 ctatagataa aggatagaga gtaatgacat tagtttatca atcaacgcgt gatgccaaca
     2521 atacagtaac tgccagccaa gcaattttgc aaggtttggc gacggacggc ggtttgttta
     2581 caccggttac ttatccaaag gtagatttgg actttgacaa attgaaagat gcttcttatc
     2641 aggaagttgc taagctagtt ttgtcagcat ttttagatga ctttacagct gaggagttgg
     2701 actactgtat caacaatgcc tacgatagca aatttgatac tccagctatt gcaccattag
     2761 tgaaattaga tgggcaatac aatttggaac ttttccatgg ttcaacgatt gcctttaagg
     2821 atatggcctt gtctattttg ccatacttta tgacgactgc tgctaagaaa catggtttgg
     2881 agaacaagat tgttatcttg acagcgacat ctggtgacac ggggaaagct gctatggcgg
     2941 ggtttgcgga tgtgcctggt actgagatta tcgtctttta tccaaagggt ggtgtcagca
     3001 aggtacaaga gttgcaaatg accactcaga atggtgacaa tactcatgtt atcgctatag
     3061 atggtaactt tgacgatgcg caaaccaacg tgaagcacat gtttaacgac gtggctcttc
     3121 gtgaaagatt agcggccaac aagttgcaat tttcatctgc taactctatg aatatcggtc
     3181 gtttggtgcc acagattgtt tattatgttt atgcctatgc tcagttggtc aagactggtg
     3241 agatcgtggc tggtgataag attaacttca cagtaccaac aggaaacttt ggaaatatct
     3301 tggctgcctt ttatgccaaa caaatcggtc tcccagttgg taaattgatc tgtgcttcaa
     3361 atgataacaa tgttttgaca gacttcttca agacacgtgt ttacgacaag aaacgtgagt
     3421 ttaaggtaac aaccagccca tctatggata tcttggtatc ttcaaacttg gagcgtttga
     3481 ttttccatct tttggggaat gatgcggtta agacggctga actcatgaat accttgaata
     3541 cacaaggaca atatgaactg actgattttg atgtagagat tctggagctc tttgcagctg
     3601 aatatgcgac tgaggaagaa acagcggcag aaatcaagcg tgtttatgag ttagattctt
     3661 atattgagga tccacatacg gcggttgcct cagcagttta tagaaaatac caagcggtta
     3721 ctgatgatgc gactaagaca gtgattgctt caacagctag tccctacaag ttcccagtag
     3781 ttgcagtaga agctgtaact ggaaaagcag gtttaacaga ctttgaagct ttggctcaat
     3841 tacatgaaat ctcaggcgtt gcagtgccac cagcagttga tgggcttgag acagctcctg
     3901 ttcgtcacaa gacaacagtg gcagctgctg acatgcaagt agcggttgag gcttatttag
     3961 gactttaaga tagagggagt aaactcggtt gggaaaccaa ctgagtttct tttcatcagg
     4021 aggagagatt gtttaagaaa aataaagaca ttcttaatat tgcattgcca gctatgggtg
     4081 aaaacttttt gcagatgctc atgggaatgg tggacagtta tttggttgct catttaggat
     4141 tgatagctat ttcaggggtt tcggtagctg gtaatattat caccatttat caggcgattt
     4201 tcatcgctct gggagctgct atttccagtg ttatttcaaa aagcataggg cagaaagacc
     4261 agtcgaagtt ggcctatcat gtgactgagg cgttgaagat taccttacta ttaagtttcc
     4321 ttttaggatt tttgtccatc ttcgctggga aagagatgat aggacttttg gggacggaga
     4381 gggatgtagc tgagagtggt ggactgtatc tatctttggt aggcggatcg attgttctct
     4441 taggtttaat gactagtctg ggagccttga ttcgtgcaac gcataatcca cgtctgcctc
     4501 tctatgttag ttttttatcc aatgccttga atattctttt ttcaagtcta gctatttttg
     4561 ttctggatat ggggatagct ggtgttgctt gggggacaat tctgtctcgt ttggttggtc
     4621 ttgtgatttt gtggtcacaa ttaaaactgc cttatgggaa gccaactttt ggtttagata
     4681 aggaactgtt gaccttggct ttaccagcag ctggagagcg acttatgatg agggctggag
     4741 atgtagtgat cattgccttg gtcgtttctt ttgggacgga ggcagttgct gggaatgcaa
     4801 tcggagaagt cttgacccag tttaactata tgcctgcctt tggcgtcgct acggcaacgg
     4861 tcatgctgtt ggcccgagca gttggagagg atgattggaa aagagttgct agtttgagta
     4921 aacaaacctt ttggctttct ctgttcctca tgttgcccct atcctttagt atatatgtct
     4981 tgggtgtacc attaactcat ctctatacga ctgattctct agcggtggag gctagtgttc
     5041 tagtgacact gttttcacta cttggaaccc ctatgacgac aggaacagtc atctatacgg
     5101 cagtctggca gggattagga aatgcacgcc tcccttttta tgcgacaagt ataggcatgt
     5161 ggtgtatccg cattggaaca ggatatctga tggggattgt gcttggttgg ggcttacctg
     5221 gtatttgggc agggtctctc ttggataatg gttttcgctg gttatttcta cgctatcgtt
     5281 accagcgcta tatgatcttg aaaggatagg aaatgcaaaa aacagctttt atttgggatt
     5341 tagacgggac tttattggac tcttacgaag cgattttatc agggattgag gagacttttg
     5401 ctcagttttc tattccttat gataaggaga aggtgagaga gtttatcttc aagtattcgg
     5461 tgcaagattt gcttgtgcgg gtggcagaag atagaaatct ggatgttgag gtgctaaatc
     5521 aggtgcgtgc ccagagtctg gctgagaaga atgctcaggt agttttgatg ccaggtgcgc
     5581 gtgaggtgct agcttgggca gacgaatcag gaattcagca gtttatatat actcataagg
     5641 ggaacaacgc ttttaccatt ctcaaggact tgggggtgga atcctatttt acagagattt
     5701 taaccagtca gagtggcttt gtgcggaagc caagtccaga agcggctacc tatctgctag
     5761 ataagtatca gttgaattct gataatactt attatatagg ggatcggact ctggatgtgg
     5821 aatttgccca gaatagtggg attcaaagta tcaacttttt agagtctact tatgaaggga
     5881 atcacaggat tcaagcgtta gcagatattt cccgtatttt tgaggctgaa cgataaaaag
     5941 attgtgtcag ttttgtgaca gagacctaac aaactatttc aagtaaccta gtttgttaca
     6001 aggaatagac agttctgtta aataggcccg agagggcttt ttttctacat tttttgtgtt
     6061 atcatagaca ggtactcatt tgaaaggatt tgaaagaatg aagaaaagaa tgttattagc
     6121 gtcaacagta gccttgtcat ttgccccagt attggcaact caagcagaag aagttctttg
     6181 gactgcacgt agtgttgagc aaatccaaaa cgatttgact aaaacggaca acaaaacaag
     6241 ttataccgta cagtatggtg atactttgag caccattgca gaagccttgg gtgtagatgt
     6301 cacagtgctt gcgaatctga acaaaatcac taatatggac ttgattttcc cagaaactgt
     6361 tttgacaacg actgtcaatg aagcagaaga agtaacagaa gttgaaatcc aaacacctca
     6421 agcagactct agtgaagaag tgacaactgc gacagcagat ttgaccacta atcaagtgac
     6481 cgttgatgat caaactgttc aggttgcaga cctttctcaa ccaattgcag aagctccaaa
     6541 agaagtagca tcaagttcag aagttacaaa gacagtgatt gcttctgaag aagtggcacc
     6601 atctacgggc acttctgtcc cagaggagca aacggccgaa acaactcgcc cagttgaaga
     6661 agcaactcct caggaaacga ctccagctga gaagcaggaa acacaagcaa gccctcaagc
     6721 tgcattagca gtggaagcaa ctacaacaag ttcagaagca aaagaagtag catcatcaaa
     6781 tggagctaca gcagcagttt ctacttatca atcagaagaa acgaaagtaa tttcaacaac
     6841 ttacgaggct ccagctgcgc ccgattatgc tggacttgca gtagcaaaat ctgaaaatgc
     6901 aggtcttcaa ccacaaacag ctgcctttaa agaagaaatt gctaacttgt ttggcattac
     6961 atcctttagt ggttatcgtc caggagacag tggagatcac ggaaaaggtt tggctatcga
     7021 ctttatggta ccagaacgtt cagaattagg ggataagatt gcggaatatg ctattcaaaa
     7081 tatggccagc cgtggcatta gttacatcat ctggaaacaa cgtttctatg ctccattcga
     7141 tagcaaatat gggccagcta acacttggaa cccaatgcca gaccgcggta gtgtgacaga
     7201 aaatcactat gatcatgttc acgtttcaat gaatggataa acccgacttg ataacatcat
     7261 tttgacgaat gagatctagc tttcgtgatg gaaagcgatt ctcgttcgtt ttttctttgt
     7321 catactcttc gaaaatctct tcaaaccacg tcagttttat ctgagacctc aaagctgtgc
     7381 tttgagcaac ctgcgactag cttcctagtt tgctttttga ttttcattga gtatcaattt
     7441 gaatggaaaa tggaaagtta tcatcttgta atgagttaag caacattctt gcaatctatt
     7501 ttactttata tcacaattaa ttagtcaaat attgataaat caataaaaag agaggggaag
     7561 aaatgctaga gattcaagat ttactgtatc aactccgctt gtctgagcaa gcgagtacgc
     7621 aattgtttga aaaaaggctt gggattagtt tgacacggta tcagatttta ctgtttttgc
     7681 tggagcattc tccttgtaac caaatggcgg ttcaggagcg tttgaaaatt gatcaggctg
     7741 ctttgacacg gcatttcaaa attttggaaa cggaaggttt ggtggagcgt catcgtaatc
     7801 ctgaaaatca gcgggaagtg ttggtagagg ctgcgaagta tgccaaggag cagttagtgg
     7861 tgaatccccc tctgcaacat atcagggtta aggaagagat agaaagtatc ttaacagagt
     7921 ttgagagaac agaactcagc cgtttattaa ataaattggt tttgggtatt gaaaatatag
     7981 aaatttaagg agaaatagat gtcaattatt ttaacaacga tcgttgcttt ggagcatttt
     8041 tacatttttt atttggaaag tattgccacg caatcagatg cgactagtcg tgtatttaat
     8101 atggaaaagg aagaattggc tcatccgtca gtaagttcat tgttcaaaaa tcaaggaatt
     8161 tataaggctc tgctaggagt ctttctcttg tatgtcattt atttctcaca gaatttagaa
     8221 attgtgacta tttttgtctt atttgtgatt ggtgctgcga cttacggctc tttaacagcg
     8281 gataaaaaaa ttattttgaa acaaggtgga tcagctattt tggccttgat tagtatttta
     8341 ctctttaaat acacttgaag gtcgattcta atctcgctaa tcctttttaa tccagaataa
     8401 gggaaatatg ttatacttgt ttttaagaaa aaagtttcat tgaattggtt ttgaggagtt
     8461 agaaatgaaa gtattagtga caggttttga gcccttttga ggccattaaa ggtttaccag
     8521 ctgaaatcca tggtgctgag gtccgttggc tagaggtgcc gacagttttt cacaaatctg
     8581 ctcaagtatt ggaagaagag atgaatcgtt atcaacctga ctttgtcctt tgtattgggc
     8641 aagctggtgg aagaactagt ttgacacctg aacgagtggc cattaatcaa gacgatgcac
     8701 gtacttctga taacgaagat aatcaaccga ttgaccgtcc cattcgccca gatggtgctt
     8761 cggcctactt tagtagtttg ccgattaaag cgatggttca agctataaaa aagaaggatt
     8821 accggcctct gtttccaata cggcagggac ttttgtctgc agccatttga tgtatcaggc
     8881 tctctatttg gtagaaaaga aatttccata tgttaaggca ggttttatgc atattcctta
     8941 tatgatggaa caggtggtga acagaccgac tactccaact atgagtttag tggatattcg
     9001 gcgagggata gaagcagcaa tcggcgctat gatagaacat ggagatcagg aactcaagtt
     9061 ggtaggcgga gaaattcatt gatagaaaaa agcttgaggg gaaaaccttc aagcttttgg
     9121 acgttttcga gccaatactg ctcggtaaaa cataatttta gtgcattgga tataaggtag
     9181 gagtgaaaaa ctagcaatgc caaaggtaat ccaattgagg aagtaccaag gaagaagctg
     9241 taaatctagg acaaagtgct ggaacttgta gcccttcata aaggaacggc tagtttttag
     9301 gattcgtctt ggtgggacct gtcctaggtc tagactatga cagagaagaa attccacctg
     9361 tgaataggca taatactgtg gaatatagag gatatttcct acaatgatca agatgagact
     9421 tgcaagaaag tagagtccaa agaccatgag gaaacgctcg gtttcaactg atgagagatc
     9481 tagatttgga aactcaggat gtagggtgac gaattttttg gctaaaaagc tactataaaa
     9541 gaggaggtaa atcccaagta aattagggat actccataaa aagagataga aacgtttgag
     9601 aagtagggtc aaaaaggttt gagaaaagcg ctcctcatca aagagagcta ggctgttttt
     9661 tacagatggc tccgttttag aatctttcat gagtgtcagt gttgcataga cggaactggt
     9721 caaaagaata gtcccgataa aggagactag tagaggaaag aggtaggctt gaagtatttg
     9781 gccaagtatg ctgaaaaatg gctgttctaa aacagtcccg tggatccgag ataagggatt
     9841 aagaaaacca gataagatga ccagcatact gggaaggata tagaggagaa agagacgggg
     9901 ggtgtcagcc tgaaaatgtt ttgactcctg acgaattgtt tttaaatcaa tttttggata
     9961 gttcattctc ttattatacc atagttctta tacatagttc gtgacagttc ctactttttt
    10021 tgataaaatc atacagtgtg tccttgggca cactgtatga actgggactg tctttcccag
    10081 cttcggaggt aaaaaatgtc agattcacca atcaaatatc gtttgattaa gaaagaaaaa
    10141 cacacaggag ctcgtctagg agaaatcatc actccccacg gtacctttcc gacacctatg
    10201 tttatgccag ttgggacaca agccactgtc aaaactcagt cacctgaaga attgaaggag
    10261 atgggttcgg gaattatcct atcaaacacc tatcatctct ggcttcgccc tggagatgaa
    10321 ctcattgcac gcgctggtgg tctccacaag ttcatgaatt gggaccagcc tatcttgaca
    10381 gatagtggtg gttttcaggt ttattcttta gcagatagcc gtaatatcac agaagaagga
    10441 gtaaccttta aaaatcatct aaatggttct aagatgttcc tatccccaga aaaagccatc
    10501 tctattcaga ataatctggg ttcagacatc atgatgtcct ttgatgaatg tcctcagttt
    10561 tatcaacctt atgactacgt taagaaatcg atcgagcgta ccagccgttg ggctgagcgt
    10621 ggtttgaagg ctcaccgtcg tccacatgac caaggtttgt ttggaattgt gcaaggtgca
    10681 ggatttgaag accttcgccg ccaatcagct catgatcttg tcagcatgga tttctcaggc
    10741 tactctatcg gtggtttggc agtgggagaa acccatgaag agatgaatgc ggtcttggac
    10801 tttacaactc aactgctgcc tgaaaataaa cctcgttatc tgatgggtgt gggagcgcca
    10861 gatagcttga tcgatggggt cattcgtggg gtggatatgt ttgactgtgt cttaccgact
    10921 cgaattgctc gtaacgggac ttgtatgacc agtcaaggac gtttggttgt gaaaaatgcc
    10981 cagtttgctg aggactttac gccactggat cctgagtgtg attgctacac atgtaataac
    11041 tatacacgcg cttaccttcg tcacctgctc aaggctgatg aaacctttgg tatccgcttg
    11101 actagctacc acaatcttta cttcttgctt aacttgatga agcaagtgcg acaagccatc
    11161 atggatgaca atctcttgga attccgtgag tattttgtgg aaaaatatgg ctataataag
    11221 tcaggacgta atttctaaaa tggaattgat ataagctaaa aatcctaagt tttctcttag
    11281 gatttttctt ctttttttga tagaataaag tgtacaatga aaggaagaat aaactcgtat
    11341 gcgcattaaa tggttttcct tggttaggat tacaggttta cttttggtac tcttgtatca
    11401 cttctttcag acgatctttc ctggaggatt tttcggggta gatgtctttt tcacattttc
    11461 aggtttcctg attacagctc tactcattga agaattttct aaaaaccatg agattgattt
    11521 gataggattt tttagaagac gcttttatcg gattgtgcca cctgtggttt tgatggtctt
    11581 ggtgaccatg ccttttactt tcttggttcg ccaagactat gttgctggaa ttggtggcca
    11641 gattgcgagc gtcttaggct ttatgaccaa cttctatgaa ctcctaacag gtgggagtta
    11701 tgaatctcag ttcattcctc atttgtttgt tcataattgg agtttggcag ttgaggttca
    11761 ctactatatt ctttggggat tggcagtttg gttcttatcc aaacaagcta aatcaaatgg
    11821 tcagttgaag gggatggtct ttctcttatc tgctgttgcc ttcttgatca gtttcttctc
    11881 catgtttatt ggtagttttc tagtgacctc ttattcctct gtttatttct ccagtttaac
    11941 tcatgtctat ccattctttt tgggaagtat gttagcaact attgtaggcg ttcgtcagac
    12001 gacttccctc gtcaagcagt tggataaaat ctgggattta cgaaagactt tggtagtttt
    12061 tggaggaggc tttggtttcc tagttctttt gactttcttt gtcaaattca cttatctttt
    12121 tgcctatctt atcggcttct tacttgccag tcttgcagct cttgccatga ttctggcggc
    12181 gcgtgtctta catgaaaaga cacatcatat acaggagccg aagattatca gctttttagc
    12241 ggatactagc tatgcggttt atcttttcca ttggcctttc tatatcattt tctcacagtt
    12301 gacatcaaat cttcttgctg tattactgac tctgatttgt tcttatggct ttgccagtct
    12361 gtcattttat gtattggaac cttggattgc aggcaagaac acacctattg tccaaaccct
    12421 tcgtcccctg ccttatattc acgcaattct tgcagcaggt acaggaatct tgaccatcat
    12481 tgtctgcacg gtgaccttgt tggcaccaca agtgggagcg tttgagacag acttgactgt
    12541 caatggcttg aagcaagctg caacaaatat tggccagacc aaggtgatgg cagaacgggc
    12601 agatgcaaac agtttgggaa ttgctgatgg cactatgtta attggtgact cagtggcttt
    12661 aagggcaaat acagcactac agacagctct tcctggagca cagattaacg cgcaggtcag
    12721 cgtaacaacc aagaccgcaa atgaaatcat gctaaataat agccagaata aatttttacc
    12781 taagacggtg gtcattgcga ctggggtaaa taatcctgag aattacaagg atgactggga
    12841 cagtatcgtg aaaaatcttc ctaagggaca ccatatgatt ttggtgactc cttatgaggg
    12901 agataagaca aaagagacct atgccatcgt tgagaaggct gctgcctata tgagagaatt
    12961 ggcagagaag acaccttaca ttacgatagc agattggaat caagttgcga aagagcatcc
    13021 agaaatttgg gctggaacag accaggttca tttcgggagt gagagtagca ctatcgaagc
    13081 aggagcaaaa ttgtatgcag atacgattgc cacagctttg cagacagctc aagacaagcc
    13141 ggttaaatca aaataacttg tattaaaaaa gagaagagtt ggagaaatcc agctctttta
    13201 aaatatctcc aaaaaatagg tctataccat ttacaaataa aaaagaaagg tttataatgt
    13261 aattgacata ataaattgta gaatcaatct tttaaggagg ttaacattat gcctaactat
    13321 attaaagcgg atcagttttt ctacccacac ggagttcgtc gaggtggtta cttggaactt
    13381 gtggacggca agtttgggaa acatgtagag cagattcctg aaggggctga ggtgattgac
    13441 tatacaggtt atagcattgc cccaggtctt gtggatactc atattcatgg atatgcaggt
    13501 gtagatgtga tggacaacaa cattgaaggt acattgcata ctatgagtga aggacttctt
    13561 agtaccggtg ttaccagttt cttacccaca actttaacag ccacttatga gcaattgctt
    13621 gcagtcactg aaaatcttgg aaaccattat aaagaagcaa caggtgctaa gattcgtggg
    13681 atttattatg aaggtccata tttcacagaa acttttaagg gggcacaaaa tccaacttat
    13741 atgagagacc cgggtgttga ggagtttcat tcttggcaaa aagcggcaaa tggcttgctt
    13801 aataaaattg cccttgcacc agaacgtgat ggggtggaag actttgttcg tacagttacg
    13861 ggcgaaggtg tgacggttgc tcttggacat tcaaacgcga cttttgatga agccaaaaaa
    13921 gcagtcgatg ctggagcgag tgtttgggtg catgcctaca atggaatgcg tgggttgact
    13981 caccgtgaat tgggtatggt tggagccatg taccaattgc cacataccta tgcagagttg
    14041 atctgtgatg gtcaccacgt agatccaaag gcttgcgaaa ttcttatcaa acaaaaagga
    14101 acagaaaaca tcgctcttat cacagactgt atgacagctg ggggattgga agacggagat
    14161 tatatgttgg gagaattccc agttgtcgtt gcaaatggaa ctgcacgcct caaatcgaca
    14221 ggtaacttgg caggttctat cctcaaactc aaagatggtt tgaagaatgt ggtcgaatgg
    14281 ggaattgcga atccgcatga agcagtcatg atggccagct tcaacccagc taaatccgtt
    14341 cacatcgatg acgtctgtgg ccaaatccgt gaaggctacg acgctgactt catcgtatta
    14401 gataaagatt tggaattggt agcaacctac ctagatggcg taaaacgtta tcaagcataa
    14461 gagagaaagc agaagttaga gactaacttc tgctttttta tgcagggtac tttactggta
    14521 aataaaaagt taaaaaaatc acaaaaaaag cttgaagaaa caaagaaaaa ggcttacaat
    14581 tgaactataa atattacaaa taaaaaaacg gaggagtgct ttatgaaagc ctatacttat
    14641 gttaaaccag gacttgcttc ttttgttgat gtagacaaac cagttattcg caagccaaca
    14701 gacgctattg tgcgtattgt aaaaaccact atttgtggaa cagacctcca tattatcaaa
    14761 ggggatgttc ctacttgcca aagtggtacc attcttggcc acgaagggat tgggattgtt
    14821 gaagaagttg gggaaggagt ttccaacttc aaaaaaggtg acaaggtctt gatttcttgc
    14881 gtctgtgcct gtggtaaatg ctactactgt aaaaaaggaa tttatgctca ctgtgaagac
    14941 gaagggggct ggattttcgg tcacttgatt gatggtatgc aggctgaata tctacgtgtc
    15001 cctcatgcag ataatactct ttaccatact ccagaagact tgtcagatga agctttggtt
    15061 atgctgtcag acattctgcc tactggatat gaaattggtg tcttaaaagg gaaagtagaa
    15121 cctggttgca gcgtagccat tattggttca ggtccagttg gattggctgc tcttttaaca
    15181 gcccaattct attcaccagc taaattgatt atggtagacc tagacgataa ccgcttggaa
    15241 actgccctat cattcggtgc gactcataag gttaattctt cagaccctga aaaagccatt
    15301 aaagaaattt atgatttgac agatggtcgt ggtgtggatg tcgctatcga agctgttggt
    15361 attcctgcaa catttgattt ctgtcaaaag attatcggtg tagacggaac ggttgccaac
    15421 tgtggtgtgc atggtaaacc agttgaattc gatttagata aactttggat tcgcaacatc
    15481 aatgtaacaa ctggtttggt atctacaaat acgactccac aattgttgaa agcgcttgaa
    15541 agtcataaga ttgaaccaga aaaattggta actcactatt tcaaactcag tgaaattgaa
    15601 aaagcctacg aagtcttcag taaggcagca gaccaccatg ccattaaggt cattatcgaa
    15661 aacgatatct cagaagccta agtagtaaaa atatttttgt acataagtaa atagaaattc
    15721 agtcatccat cagatggctg gattttttat caaaaaatta agaaatgagc atatttcttt
    15781 ccttgtctgg cggaattggt tataatatac ggtacaaagg aatgaatgaa tatgtatcgt
    15841 gttatagaaa tgtacggaga ttttgaaccg tggtggttct tagaaggttg ggaagaagat
    15901 attgtagcaa gtagaaaatt tgaccagtat tatgatgctc tcaaatacta caaaacttgc
    15961 tggtttagat tggaacaaga atcccctctt tataaaagta gaagcgactt gatgaccatt
    16021 ttttgggacc cggaagacca acgctggtgt gatgaatgtg atgagtattt acaacaatac
    16081 cattctttgg ctcttttgca ggatgagcag gttatcccag acgaaaaact acgctcaggc
    16141 tatgaaaaac aaaccagtca ggaaaggaat cgttcttgcc gtatgaaatt aaaatagaga
    16201 aaagtaactt ttttggagtt gcttttttta tttttctaac gctttgcgaa tagtataggt
    16261 gaggaggtaa gtatggttca agaaattgca caagaaatca ttcgctcggc tcggaaaaaa
    16321 ggggcgcaag acatttattt tgtccccaag ttagacgcct atgagcttca tatgagggta
    16381 ggagacgagc gctgtaaaat tggtagctat gattttgaaa agtttgcagc cgttatcagt
    16441 cactttaagt ttgtggcggg tatgaatgtg ggagaaaaaa gacgtagtca actgggttcc
    16501 tgtgattatg cctatgacca gaagatggcg tctctacgtt tatctactgt aggcgattat
    16561 cgggggcatg agagtttggt tatccgtttg ttgcacgatg aggagcagga cttgcatttt
    16621 tggtttcagg atattgaaga attaggcaag cagtacaggc aacggggact ctatcttttt
    16681 gctggtccgg ttgggagtgg taagacgacc ttgatgcatg aattgtccaa gtcactcttt
    16741 aaaggacagc aagttatgtc catcgaagat cctgtcgaaa tcaagcagga cgacatgctt
    16801 cagttgcagt tgaacgaagc aatcggtcta acctatgaaa atctaatcaa actttccttg
    16861 cgtcatcgac cagatctctt gattatcgga gaaattcgtg acatcgagac ggcgcgtgca
    16921 gtggtcagag ctagtttgac aggtgcgaca gtcttttcaa ccattcacgc caagagtatc
    16981 cgaggtgttt atgagcgtct gctggagttg ggtgtgagtg aagaagaatt ggcagttgtt
    17041 ctgcaaggag tctgctacca gagattaatc gggggaggag gaatcgttga ctttgcaaac
    17101 agagattatc aagaacacca agcagccaag tggaatgagc aaattgacca gcttcttaaa
    17161 gatggacata tcacaagtct tcaggctgag acggaaaaaa ttagctacag ctaagcaaaa
    17221 aaatatcatc accctattta acaatctctt ttctagcggt tttcatctgg tggagactat
    17281 ctccttttta gataggagtt ccttgttgga caagcagtgt gtgacccaga tgcgtacagg
    17341 cttgtctcag gggaaatcat tctcagaaat gatggaaagt ttgggatgtt caagtaccat
    17401 tgtcactcag ttatctctag ctgaagttca tggcaatctt cacctgagtt tgggaaagat
    17461 agaagaatat ctagacaatc tggccaaggt caagaaaaag ttaattgaag tagcgaccta
    17521 tcctttgatt ttgctgggtt ttcttctctt aattatgctg gggctacgga attacctgct
    17581 cccacaactg gatagtagca atattgccac ccgaattatc ggtaatctgc cacaaatttt
    17641 tctaggcatg gtagggcttg tttccgtgct tgccctttta gcactaactt tttataaaag
    17701 aagttctaag atgagtgtct tttctatctt agcacgcctt ccctttattg gaatctttgt
    17761 gcagacctac ttgacagcct attatgcacg tgaatggggg aatatgattt cacagggaat
    17821 ggagctgacg cagatttttc aaatgatgca ggaacaaggt tcccagctct ttaaagaaat
    17881 cggtcaagat ctggctcaaa ccctgaaaaa tggccgtgaa ttttctcaga cgataggaac
    17941 ctatcctttc tttaggaagg aattgagtct catcatagag tatggggaag ttaagtccaa
    18001 gctgggtagt gagttggaaa tctatgctga aaaaacttgg gaagcctttt ttacccgagt
    18061 caaccgcacc atgaatttgg tgcagccact ggtttttatc tttgtggcac tgattatcgt
    18121 tttactttat gcggcaatgc tcatgcccat gtatcaaaat atggaggtaa atttttaaaa
    18181 tgaaaaaaat gatgacattc ttgaaaaaag ctaaggttaa agcttttaca ttggtggaga
    18241 tgttggtggt cttgctgatt atcagcgtgc ttttcttgct ctttgtacct aatctgacca
    18301 agcaaaaaga agcagtcaat gacaaaggaa aagcagctgt tgttaaggtg gtggaaagcc
    18361 aggcagaact ttatagcttg gaaaagaatg aagatgctag cctaagcaag ttaaaagaag
    18421 atggacgcat cacggaagaa caggctaaag cttataaaga atacaatgat aaaaatgtgg
    18481 gagcaaatcg taaagtcaat gattaaggcc tttaccatgc tggaaagtct cttggttttg
    18541 ggtcttgtga gtatccttgc cttgggcttg tccggctctg ttcagtccac ttttgcggcg
    18601 gtagaggaac agattttctt tatggagttt gaagaactct atcgggaaac ccaaaaacgc
    18661 agtgtagcca gtcagcaaaa gactaatcta aatttagatg ggcagacgct tagcaatggc
    18721 agtcaaaagt tgacagttcc taaaggaatt caggcaccat caggccaaag tattacattt
    18781 gaccgagctg ggggcaattc gtccctggct aaggttgaat ttcagaccag taaaggagcg
    18841 attcgctatc aattatatct aggaaatgga aaaattaaac gcattaagga aacaaaaaat
    18901 tagggcagtg attttactgg aagcagtagt cgctctagct atctttgcca gcattgcgac
    18961 cctccttttg ggacaaattc aaaaaaatag gcaagaggaa gcaaaaatct tgcaaaagga
    19021 agaagtcttg agggtagcta agatggccct gcagacgggg caaaatcagg taagcatcaa
    19081 cggagttgag attcaggtat tttctagtga aaaaggattg gaggtctacc atggttcaga
    19141 acagttgttg gcaatcaaag agccataagg tcaaggcttt taccttgtta gaatccctac
    19201 ttgccctcat tgtcatcagt gggggattac tcctttttca aactatgagt cagctcctca
    19261 tttcagaagt tcgctaccag caacaaagcg agcaaaagga gtggctcttg tttgtggatc
    19321 aacttgaggc agaattagac cgttcgcagt tcgaaaaagt agaaggcaat cgcctataca
    19381 tgaagcaaga tggcaaggac atcgccatcg gtaagtcaaa gtcagacgat tttcgtaaaa
    19441 cgaatgctcg tggtcgaggt tatcagccta tggtttatgg cctcaaatca gctcagatta
    19501 cagaggacaa tcaactggtt cattttcgtt tccagtttca aaaaggctta gaaagggagt
    19561 tcatctatcg tgtggaaaaa gaaaaaagtt aaggcaggtg ttctcctcta cgcagtcacc
    19621 atagcagcca tctttagtct tttgttgcaa ttttatttga accgacaagt cgcccactat
    19681 caagactatg ctttgaataa agaaaaattg gttgcttttg ctatggctaa acgaaccaaa
    19741 gataaggttg agcaagaaag tggggaacag gtttttaatc taggtcaggt aagctatcaa
    19801 aacaagaaaa ctggcttagt gacgagggtt cgtacggata agagccaata tgagtttctg
    19861 tttccttcag tcaaaatcaa agaagagaaa agagataaaa aggaagaggt agcgaccgat
    19921 tcaagcgaaa aagtggagaa gaaaaaatca gaagagaagc ctgaaaagaa agagaattcc
    19981 tagtcaattc aactataatg cgttgaatcc agaatagtcc actgtagttt ctagaaaatt
    20041 gctggaaatg gatgttaagc tccaattcat ttgtttatat cttatttcag tttactatac
    20101 tttgtgctaa attaaagata tgaaacatga ttttaaccac aaagcagaaa ctttcgattt
    20161 ccctaaaaat atcttcctcg caaacttggt atgtcaagca gccgagaaac agattgatct
    20221 tctatcagac aaagaaattt tagatttcgg tggtggcacg ggtctattag ccttgcccct
    20281 aacccctagc caagcaggct aagtcagtca ctcttgtaga catttctgag aaaatgttgg
    20341 agcaagctcg tttgaaagtg gagcagcaag caatcaagaa tatccagttt ttggagcaag
    20401 atttaccgaa aaatcccttg gagaaagagt ttgattgcct tgctgttagt cgggttcttc
    20461 atcatatgcc tgatttggat gcggctctct cactgtttca tcaacatttg aaggaagatg
    20521 ggaaactcat cattgctgat tttaccaaga cagaagctaa tcatcatgga tttgatttag
    20581 ctgaactgga aaacaagcta attgagcatg gtttttcatc tgtgcatagt cagattctct
    20641 atagcgctga agacctgttt caaggaaatc actcagaatt ctttttaata gtagcccaaa
    20701 aatcactcgc ctagtcaggg agtgattttt ctataagaat ggaaaaaaga agggaaattt
    20761 gataagatag gaatatggat tttgaaaaaa ttgaacaagc ttatacctat ttactagaga
    20821 atgtccaagt catccaaagt gatttggcga ccaactttta tgacgccttg gtggagcaaa
    20881 acagcatcta tctggatggt gagactgagc tagaacaggt caaagacaac aatcagaccc
    20941 ttaagcgttt agcactacgc aaagaagaat ggctcaagac ctaccagttt ctcttgatga
    21001 aggctgggca aacagaaccc ttgcaggcca atcaccagtt tacaccggat gctattgctt
    21061 tacttttggt gtttattgtg gaagagctgt ttaaagagga ggaaattact atcctcgaaa
    21121 tgggttctgg gatgggaatt ttgggcgcta ctttcttgac ctcgcttact aaaaaggtgg
    21181 attatttggg aatggaagtg gatgatttgc tgattgatct ggcagctagc atggcagatg
    21241 taattggttt gcaggctggc tttgtccaag gagatgccgt tcgtccacaa atgctcaaag
    21301 aaagcgatgt ggtcatcagt gacttgcctg ttggctatta tcctgatgat gccgttgcgt
    21361 cgcgccatca agttgcttct agccaagaac atacttacgc ccatcacttg ctcatggaac
    21421 aagggcttaa gtacctcaag tcagacggat acgctatttt tctagctccg agtgatttgt
    21481 tgaccagtcc tcaaagtgat ttgttaaaag aatggctgaa agaagaggcg agtctggttg
    21541 ctatgattag tctgcctgaa aatctctttg ctaatgctaa acaatctaag actattttta
    21601 tcctacagaa gaaaagtgaa atagcagtgg agccttttgt ttatccactt gctagcttgc
    21661 aagatgcaag tgttttaatg aaatttaaag aaaattttca aaaatggact caaggtactg
    21721 aaatataaaa tagattttgt tataatagtt gaaaacgctt aaaaaggggt atcatgttat
    21781 gacaaaaaca attgcaatca atgcaggaag ttcaagtttg aaatggcaat tatacttaat
    21841 gccagaggaa aaagtgttag ccaaaggttt gattgaacgt atcggtttga aagattcaat
    21901 ttcaactgta aaatttgacg gccgttctga acaacaaatt ttggatatcg aaaatcatac
    21961 acaagctgtt aaaattttat tggatgactt gattcgtttc gatattatca aggcttatga
    22021 cgagattaca ggtgttggac atcgtgttgt tgctggtgga gaatatttca aagaatcaac
    22081 agttgttgag ggagatgttt tagaaaaagt tgaagagttg agtttgttgg ctcctctaca
    22141 caacccggcc aatgcagcag gtgttcgtgc cttcaaggaa ttgttgccag acattaccag
    22201 tgtagttgtt tttgatactt ccttccacac aagtatgcca gagaaagctt atcgctaccc
    22261 tctaccaaca aaatattaca cagaaaacaa ggttcgtaaa tacggtgctc atggtacaag
    22321 tcaccagttt gtagcaggag aagctgcaaa actcttggga cgtccattag aagacttgaa
    22381 gttaattacc tgtcatattg gtaacggagg ctcaattaca gctgtgaaag ccggcaaatc
    22441 tgtagacact tctatggggt tcactcctct tggtggtatt atgatgggaa cgcgtacagg
    22501 ggatattgat ccagctatca ttccttattt aatgcaatat acagaggatt ttaacacacc
    22561 agaagatatc agtcgtgttc ttaaccgtga atcaggtctt ttgggagttt ctgctaattc
    22621 tagcgatatg cgcgatatag aagcagctgt agcagaaggg aatcacgagg ctagcttggc
    22681 ttatgaaatg tatgttgacc gtatccaaaa acatatcggt cagtaccttg cagtgctaaa
    22741 tggagcagat gccattgttt tcacagcagg tgtcggtgaa aatgcagaga atttccgtcg
    22801 tgatgtaatc tcagggattt cgtggtttgg ttgtgatgtt gatgatgaaa agaatgtctt
    22861 tggcgttaca ggagacatct caacagaggc agctaaaatc cgtgtcttgg ttattccaac
    22921 agatgaagaa ttagtcattg cccgtgacgt tgaacgcttg aaaaaataag tgaaactaaa
    22981 aaaatattca atacaaggag ttgggaaagt tatttttcca gcttcttttt ctgatgaaat
    23041 tgtccaaaac cttgctatga ttggcttttt tgaaaaatat ggtataatag tagtaattta
    23101 atagatggag ttgagttttg aagaaaaact ttcgtgtaaa aagagagaaa gattttaagg
    23161 cgattttcaa ggaggggaca agttttgcta atcgcaaatt tgtggtctac caattagaaa
    23221 accagaaaaa ccattttcga gtaggtctat cagttagcaa aaaactgggg aatgccgtca
    23281 ctagaaatca aattaagcga cggattcggc atattatcca gaatgcaaaa gggagtctgg
    23341 tagaagatgt cgactttgtt gtcattgctc gaaaaggagt cgaaaccttg ggatacgcag
    23401 agatggagaa aaatctactc cacgtattaa aattatcaaa gatttaccag gaaggaaatg
    23461 ggagtgaaaa agaaactaaa gttgactagt ttgctaggac tgtctctgtt aatcatgaca
    23521 gcctgtgcaa ctaatgaggt aactagcgat attacagccg aatcggctga tttttggagt
    23581 aaattggttt acttctttgc ggaaatcatt cgctttttat cgtttgatat tagtatcgga
    23641 gtggggatta ttctctttac ggtcttgatt cgtacagtcc tcttgccagt ctttcaggtg
    23701 caaatggtgg cttctaggaa aatgcaggaa gctcagccac gcattaaggc gcttcgagaa
    23761 caatatccag gtcgagatat ggaaagcaga accaaactag agcaggaaat gcgtaaagta
    23821 tttaaagaaa tgggtgtcag acagtcagac tctctttggc cgattttgat tcagatgccg
    23881 gttattttgg ccctgttcca agccctatca agagttgact ttttaaagac aggtcagttc
    23941 ttatggatta accttggtag tgtggataca acccttgttc ttccgatttt agcagcagta
    24001 ttcacctttt taagtacttg gttgtccaac aaagctttgt ctgagcgaaa tggagctacg
    24061 actgcgatga tgtatgggat tccagtcttg atttttatct ttgcagttta tgcgccaggt
    24121 ggagtcgccc tatactggac agtgtctaat gcttatcaag tcttgcaaac ctatttcttg
    24181 aataatccat tcaagattat cgcagagcgc gaggccgtag tacaggcaca aaaagatttg
    24241 gaaaatagaa aaagaaaagc caagaaaaag gctcagaaaa cgaaataaat aaggaggaat
    24301 ctggtaatgg tagtatttac aggttcaact gttgaagaag caatccagaa aggattgaaa
    24361 gaattagata ttccaagaat gaaggctcat atcaaagtca tttctaggga gaaaaaaggc
    24421 tttcttggtc tatttggtaa aaaaccagcc caagtggata ttgaagcgat tagtgaaacg
    24481 actgttgtca aagcaaatca acaggtagta aaaggcgttc cgaaaaaaat caatgatttg
    24541 aacgagcctg tgaagacggt tagtgaagaa accgttgacc ttggtcatgt ggttgatgct
    24601 attaaaaaaa tagaggaaga aggtcaaggt atttctgatg aagtcaaggc tgaaatctta
    24661 aaacatgaaa gacatgccag cactatctta gaagaaactg gtcacattga gattttaaat
    24721 gaacttcaaa tcgaggaagc gatgagggaa gaagcaggcg ctgatgacct tgaaactgag
    24781 caagatcaaa ctgaaaatca agacttgaaa gagatgggct tgaaggtcga gcaaagttat
    24841 gatattgccc aggtggctac ggatgtgact gcctatgttc aagcgattgt ggatgacatg
    24901 gatgttgaag ctacactttc aaatgattat aaccgtcgta gcatcaatct acaaattgac
    24961 accaacgaac caggtcgtat tatcggctac catggtaaag tcttgaaggc cttgcaactg
    25021 ttggctcaaa attatcttta caaccgctat tccaaaacct tctacgttac aatcaatgtc
    25081 aatgattatg tcgaacaccg tgcagaagtc ttgcagacct atgcgcaaaa attggcgatt
    25141 cgtgttttag aagaaggacg tagtcatcaa acagatccaa tgtcgaatag tgaacgcaag
    25201 attatccacc gtattatttc acgtatggat ggcgtgacca gttactctga aggtgatgag
    25261 ccaaatcgct atgtcgttgt agatacagaa taagtaaaat cagggttgac ctgatttttt
    25321 gctagctaga ggaggttaaa ctgatgttga ataagataag agactattta gactttgctg
    25381 gtttgcagta ccgtaatcct gataaagcgg gagcagagcg agagaagatg ctggcattcc
    25441 gccacaaagg acaagaggcc cgaaaggctt ttacagaact ggccaaagcc tttcaagcaa
    25501 gccatccaga atggcaactc caacagacta gtcagtggat gaatcaggcc cagcgtttga
    25561 gaccacattt ttgggtttat ctacagagag acggacaagt gacagaacct atgatggcct
    25621 tacgtttgta tgggacatct actgactttg gaatttcttt ggaagtcagt ttcatcgaac
    25681 gtaagaagga tgagcaaaca ctgggcaagc aggccaaagt tttagacatt ccaaccgtta
    25741 aagggattta ttatctaacc tactctaatg gtcaaagtca acggtgggag gcgaatgaag
    25801 aaaagcgtcg tactttacgc gagaaggtga gaagtcaaga agttcgaaaa gttttagtga
    25861 aggtagatgt tcctatgaca gaaaattcgt ctgaagaaga aatcgtagaa ggcttattga
    25921 agtcttattc taaaattctt ccctattatc tagctacgag aaaataagat aatttgtaaa
    25981 acatcataaa tcatacagtc caagagtgaa cagtccgctg tgtaattctt ggtctttttg
    26041 tttgcgcttt cgcattatat aataaactta caaaaacaat tcaaaaggag aacaattatg
    26101 gaagtcgttt caagtgttct aaattggttt tctagcaata ttttgcagaa tcccgcattt
    26161 ttcgtaggtt tattggtgtt gataggatat gcacttttga aaaaacctgc ccatgacgtt
    26221 ttttcagggt ttgttaaagc aacagtaggg tatatgttgc ttaacgtggg tgctggtggt
    26281 ttggttacaa cctttcgtcc aatcttagca gctcttaact acaaattcca aattggtgca
    26341 gcggttatcg acccttactt tggacttgct gcagcaaaca acaaaattgc agcagagttt
    26401 ccagattttg ttggaactgc aactacagct ctattgattg gttttggaat aaatatcttg
    26461 ctcgtagctc ttcgaaagat tacgaaggta agaaccctct ttattactgg tcacatcatg
    26521 gtacaacaag ctgcaacagt atctcttatg gttctattct tagtaccaca attgcgcaat
    26581 gcttacggta cagcagcgat tggtatcatc tgtggacttt actgggcagt tagttcaaat
    26641 atgactgttg aggcaactca acgcttgact ggtggtggcg gatttgcgat tggtcaccaa
    26701 cagcaatttg caatctggtt tgtagataaa gtagcaggac gctttggtaa gaaagaagaa
    26761 agtttagaca atcttaaatt acctaagttc ctctcaatct tccacgatac agttgttgca
    26821 tctgctacct tgatgctcgt attcttcggg gccattcttt taatcttggg tccagacatt
    26881 atgtctaata aagaagtcat cacttcagga actctattca atcctgctaa acaagatttc
    26941 tttatgtaca ttatccaaac agcctttacc ttctcagttt acttgttcgt tttgatgcaa
    27001 ggtgtccgaa tgttcgtatc tgagttgaca aacgccttcc aaggtatttc aaacaaattg
    27061 ttgccaggtt cattcccagc ggttgacgtt gcagcttctt atggatttgg ttctccaaat
    27121 gctgtcttgt caggatttac ctttggtttg attggtcaat tgattacaat tgtcttgctc
    27181 atcgtcttta aaaatccgat tcttattatt acaggatttg taccagtgtt ctttgacaat
    27241 gcagccattg cggtctacgc tgataaacgc ggcggatgga aagcggctgt tatcctttcc
    27301 tttatatcag gtgtccttca agttgctcta ggagctcttt gtgtggccct tctcgatttg
    27361 gcatcttatg gtggctacca tggaaatatc gactttgaat tcccatggct tggatttgga
    27421 tatatcttca aataccttgg tattgttggt tatgtacttg tgtgtctctt cttgcttgtt
    27481 attcctcaac ttcaatttgc caaagcaaaa gataaagaga aatattacaa cggtgaagtt
    27541 caagaagaag cttagtatct agaaaaggag aaataaaatg gttaaagtat tagcagcgtg
    27601 cggaaatgga atgggttcat caatggttat caagatgaag gttgaaaatg ctctccgtaa
    27661 gcttaatcaa acagatttta cagtcaattc atgcagtgtc ggtgaagcta aaggtttagc
    27721 agtaggatat gacatcgtaa tcgcttctct tcatttgatt caagaattgg aagggcgaac
    27781 taatgggaag ttaattgggc ttgataactt gatggatgat aaagaaatca ccgaaaaact
    27841 cagtcaagca ctacagtaaa aggttggagg gggctggaca gaaactgaga gttatcgttt
    27901 ctgtccttct ccctctttaa ataaaggagg cagatatgaa tttaaaacaa gctttaattg
    27961 acaacgactc gatccgacta ggtttagagg ctaacgattg gaaagaagca gtcaaggtag
    28021 cagtagatcc cttgattgaa agtggggcaa ttttgccaga gtattacgat gctatcattg
    28081 aatcgactga agagtatggg ccttactata tcttgatgcc aggtatggct atgccccacg
    28141 ctagacctga agctggtgtg caaagtgatg ccttttcatt gattacctta caaaatcctg
    28201 ttgtattttc agatgggaaa gaggtatctg ttttgttggc actagcagca acaagttcaa
    28261 aaattcacac aagtgtagcc attccacaaa ttattgccct gtttgaatta gacgattcta
    28321 ttgcacgttt acaggcttgc cagactaaag aagatgtctt ggctatgatt gaagaatcta
    28381 aggatagccc ttatctcgaa ggattggatt tggaaagtta gaaagaggaa taaagaaatg
    28441 acaaaaagaa tacctaattt acaagttgca ttagaccatt cagacttgca aggagcgatt
    28501 aaagcagctg tttctgttgg tcaggaagta gatattatcg aagctggaac tgtttgcttg
    28561 cttcaagttg gaagtgaact ggctgaagtc ttgcgtagcc ttttcccaga taagattatt
    28621 gtggcagaca caaaatgtgc tgatgctggt ggaacagttg ctaaaaataa tgcggttcgt
    28681 ggagcagact ggatgacttg tatctgttgt gcaaccatcc ctactatgga agcagctcta
    28741 aaggctatca agactgaacg aggagaacga ggcgaaatcc agatcgagct ttatggcgat
    28801 tggacttttg aacaagctca gctttggcta gatgcaggta tctcacaagc tatttatcac
    28861 caatctcgtg atgctcttct tgctggtgaa acttggggtg aaaaagacct taataaggtt
    28921 aaaaaactca ttgacatggg cttccgtgta tctgtaacag gtggtctaga tgtagatact
    28981 ctcaaactct ttgaaggtgt tgatgtcttt acctttatcg caggtcgtgg aattacagag
    29041 gctgcggatc cagcaggagc agcgcgtgcc ttcaaggatg aaatcagacg aatttggggg
    29101 taaatcatgg tacgtccaat tggaatttat gaaaaggcaa ccccaacaca ctttacttgg
    29161 ctagaacgtt taaattttgc caaggagtta ggctttgatt ttgtcgagat gtctattgac
    29221 gaacgtgacg agcgtttagc aagacttgac tggagtaagg aagaacgctt ggaagttgtc
    29281 aaagcaatct atgaaactgg tgttcgtatt ccttctatct gtttttcagg ccatcgtcgc
    29341 tacccattgg gttcaaaaga tccagttcta gaggaaaaat ctctagaact catgaaaaaa
    29401 tgtatcgaat tagctcaaga cttgggagtt cgtacgattc aattagctgg ttacgatgtt
    29461 tactatgagg aaaagtcacc ccagacacgc caacgtttta tcaaaaattt gagaaaagcc
    29521 tgtgactggg ctgaagaagc tcaggtggta cttgctattg aaattatgga tgatcctttc
    29581 atcaatagca tcgaaaaata tttggctata gaaaaagaga ttgactctcc cttcctcttt
    29641 gtatatccag atattggtaa tgtgtctgca tggcataatg atatctatag tgagttttat
    29701 cttggtcatc atgccatcgc aactctccat ctcaaggata cttatgcagt gacagaaagt
    29761 tcaaagggcc agttccgaga tgtacctttt gggcaaggtt gtgtcaaatg ggaagaagct
    29821 ttcgatattt taaaggaaac caattataat ggacctttcc taatcgaaat gtggtctgaa
    29881 aattgtgaaa cagtagaaga aacacgcgca gccattcaag aggcgcaagc ttttctctat
    29941 ccactcatta agaaagcagg tttgatgtaa gatgaatcaa gtaatcaatg ctatgcgtaa
    30001 acgagtctgt gatgccaatc aatcattgcc aaaacatgga cttgtcaaat ttacctgggg
    30061 gaatgtatct gaagtcaatc gcgaactcgg tgtcattgtt atcaaaccat caggcgtgga
    30121 ttatgacgaa ttgacacctg aaaacatggt agtgactgat ctagatggta agatcctaga
    30181 aggggattta agaccatctt ccgacttccc aactcatgtg caattatata aggcttggtc
    30241 agaaattggt agtgtggttc acacccattc gacagaagct gttgcttggg ctcaggcagg
    30301 tcgtgatatt cctttctacg gaacaaccca tgcagattat ttctacggtt caatcccttg
    30361 cgcccgtagt ttgaccaagg acgaagtaga agtggcctat gaaaaagata ctggcctggt
    30421 tatcgtagaa gagtttgaac atcgcggact taacccggtt gaagtaccag gaattgttgt
    30481 acgcaatcac ggtccattca cctggggcaa aaatccagag aatgctgttt atcactctgt
    30541 cgtactagag gaagtatcaa agatgaatcg ctttacagaa caaatcaatc caagagttga
    30601 acctgctccc cagtacatac tagaaaaaca ctaccaacgt aaacatggac caaatgctta
    30661 ttatggtcaa aagtaagaac gatgaaggag gagaaaaaga taaatttagc tcctcttttt
    30721 acatttgatt tttattgaga gtaaagttgg agttgaagta attttgaaag attttttaga
    30781 aatagcgctt gatatatatg gtaaaataaa aagaattgct gtgatatcaa tagatttggg
    30841 ggatttttta atatggtact ggataaggca agttgtgatt tgcttcaata tttgatggat
    30901 caagaaacgt ccaaaacgat tatggcgatt tcgaaagatt tgaaagagtc aagaaggaaa
    30961 atttattatc acattgacaa aatcaatgct gctctggttg acgaggcgct tcacatcatt
    31021 agtattccac gaattggtat tcacttaacg gaagagcaga gagatgcttg ttgtaaacta
    31081 ttatcggaag tagattcgta cgattatatc atgagtgcgc atgaacgtat gatgataatg
    31141 ttactatgga taggtatttc taaagaacgt attactattg aaaaattgat agagttaaca
    31201 gaggtatcta ggaatactgt tctcaatgat ttgaatagta ttcgttatca actaactttg
    31261 gaacaatatc aggtgacctt gcaagtgagc aagtcacagg gataccacct tcatgcccac
    31321 cctcttaata aaattcagta tcttcaatcg cttctatatc atatttttat ggaagaaaat
    31381 gccacttttg tatctatttt agaagataag atgaaagaga ggttagatga tgagtgtttg
    31441 ctttctgttg aaatgaacca attttttaag gaacaggttc ctttagttga acaagattta
    31501 gggaagaaaa taaaccatca tgaaataact tttatgttgc aggttctacc ttatttgctg
    31561 ttaagctgtc ataatgttga acagtatcaa gaaagacatc aggatataga gaaagaattt
    31621 tctttgataa gaaaaagaat agagtatcag gtgtctaaga aattaggaga acggttgttt
    31681 caaaagtttg aaatttcttt gtcaggactt gaagtttctc ttgtagctgt tctcctcctc
    31741 tcctatcgta aagatttgga tattcatgca gaaagtgatg attttcggca attaaaactt
    31801 gctttagaag aatttatctg gtattttgaa tcacaaatcc gaatggagat tgagaacaag
    31861 gatgatttgt tacgaaattt gatgatccac tgtaaagcct tgttatttag aaagacttac
    31921 ggtatttttt ctaaaaatcc tctaacaaaa caaattcgat ccaagtatgg agaattattt
    31981 ttagtcacta gaaaatctgc ggaaatttta gaaggagcat ggtttattcg gctaacagac
    32041 gatgatattg cctatttgac gattcatatt ggaggatttt taaagtatac actatcgtct
    32101 caaaaaaata tgaaaaaagt ttatctcgtt tgtgatgaag gtgttgcggt ttcgagactt
    32161 ttgctgaaac aatgcaaact ttattttcca aatgagcaaa ttgacactgt atttacaaca
    32221 gaacaattta agagtgtgga agatattgca caagttgatg tagtgattac tactaatgat
    32281 gatttggata gcagatttcc gattttaagg gttaatccta tccttgaagc agaagatatt
    32341 ttgaaaatgc tagactatct taaacacaat atatttcgta atgagagcaa aagtttcagt
    32401 gaaaatcttt ctagtcttat ttcgtcttat attgtagata gcaagttggc tagtaagttc
    32461 caagaagagg ttcaaacatt tataaatcaa gaaatagtag ttcaagcttt tttggaagat
    32521 atttgaagga cagtccaatg atgaacacaa acctgtgttt ttcttggtct tttttagtgt
    32581 tttgaagggt ggtatactaa tctcaaagat aacaattata tccaaaggag gcaacatatg
    32641 ccaaacgtca aagaaattac aagagagtca tggattttag ccactttccc agagtgggga
    32701 acatggttga acgaagaaat cgaagaagaa gtcgtacctg aaggcaactt tgccatgtgg
    32761 tggctaggca actgtggtac ttggattaag acaccagctg gtgctaacgt tgtcatggac
    32821 ctttggtcaa accgtggaaa atcaaccaaa aaagtgaaag atatggttcg tgggcaccaa
    32881 atggcaaata tggcaggtgt tcgtaagctg caaccaaact tgcgtgttca gccaatggtt
    32941 atcgatccat ttgctatcaa cgaactagac tattacttag tttcacactt ccacagtgat
    33001 catatcgacc catacacagc tgcagcaatt ctcaacaatc ctaagttaga gcatgttaag
    33061 tttatcggtc cttaccactg tggacgaatc tgggaaggat ggggtgttcc aaaagaacgt
    33121 atcatcgttg ttaaaccagg tgacactatc gaattaaaag atatgaagat tcatgcagta
    33181 gaatcatttg accgtacttg cttggtaact ctcccagtga acggtgctga tgagacaggc
    33241 ggtgaacttg ctggcttggc tgttacagat gaagaaatgg ctcaaaaggc tgttaactat
    33301 atctttgaaa caccaggtgg aaccatctat catggtgcag attctcactt ctcaaactat
    33361 tttgcaaaac atggtaaaga ctttaaaatt gatgttgctt tgaataacta tggtgaaaat
    33421 ccggtaggta tccaagacaa aatgacatct atcgaccttc ttcgtatggc agaaaatctg
    33481 cgtaccaaag tcattatccc agttcactat gatatctggt ctaacttcat ggcttctact
    33541 aatgagattc tagaactttg gaaaatgcga aaagatcgct tgcaatacga tttccatcca
    33601 tttatctggg aagttggcgg taagtacact tatcctcaag atcaacactt agtagaatac
    33661 catcatccac gtggttttga tgattgtttt gaacaagact ctaacattca atttaaagct
    33721 ttgctataat ataaaaatat tctttggagg ttatccgtat gttgcatgat acggataatt
    33781 ttcatataat agtaaaatag aatgtgtgat tcaataatca cctcaaatag aaaggaaatt
    33841 ctatgtcaaa tctatctgtt aatgcaattc gttttctagg tattgacgcc attaataaag
    33901 ccaactcagg tcatccaggt gtggttatgg gagcggctcc gatggcttac agcctcttta
    33961 caaaacaact tcatatcaat ccagctcaac caaactggat taaccgcgac cgctttattc
    34021 tttcagcagg tcatggttca atgctccttt atgctcttct tcacctttct ggttttgaag
    34081 atgtcagcat ggatgagatt aagagcttcc gtcaatgggg ttcaaaaaca ccaggtcacc
    34141 cagaatttgg tcatacggca gggattgatg ctacgacagg tcctctaggg caagggattt
    34201 caactgctac tggttttgcc caagcagaac gtttcttggc agccaaatat aaccgtgaag
    34261 gctacaatat ctttgaccac tatacttacg ttatctgtgg agacggagac ttgatggaag
    34321 gtgtctcaag cgaggcagct tcatacgcag gcttgcaaaa acttgataag ttggttgttc
    34381 tttatgattc aaatgatatc aacttggatg gtgagacaaa ggattccttt acagaaagtg
    34441 ttcgtgaccg ttacaatgcc tacggttggc atactgcctt ggttgaaaat ggaacagact
    34501 tggaagccat ccatgctgct atcgaaacag caaaagcttc aggcaagcca tctttgattg
    34561 aagtgaagac ggttattgga tacggttctc caaacaaaca aggaactaat gctgtacacg
    34621 gcgcccctct tggagcagat gaaactgcat caactcgcca agccctcggt tgggactacg
    34681 aaccatttga aattccagaa caagtatatg ctgatttcaa agaacatgtt gcagaccgtg
    34741 gcgcatcagc ttatcaagct tggactaaat tagttgcaga ttataaagaa gctcatccag
    34801 aactggctgc agaagtagag gccatcatcg acggacgtga tccagtcgaa gtgactccag
    34861 cagacttccc agctttagaa aatggttttt ctcaagcaac tcgtaattca agtcaagatg
    34921 ccttgaatgt tgtggcagct aaattaccaa ccttcctagg tggatcagct gaccttgctc
    34981 actcaaacat gacttatatc aagacggatg gacttcaaga cgataccaat cgcttgaatc
    35041 gtaacattca gtttggtgtt cgtgaatttg caatgggaac aatcttgaac gggatggccc
    35101 ttcatggtgg acttcgtgta tacggtggaa ctttcttcgt cttctctgac tatgtgaagg
    35161 cagctgtccg cttgtcagcc ttacaaggac ttcctgtgac ttatgtcttt acccatgatt
    35221 caatcgcagt tggggaagat ggtccgactc acgaaccagt tgagcattta gcaggtcttc
    35281 gtgctatgcc aaatctaaat gttttccgtc cagcagatgc gcgtgaaacg caagcagctt
    35341 ggtaccttgc agtgacaagt gagaaaacac caactgccct tgtcttgaca cgtcaaaact
    35401 tgactgttga agatggaaca gacttcgaca aggttgctaa aggtgcttat gttgtatatg
    35461 aaaatgcagc cgactttgat accatcttga ttgcgacagg ttcagaggtc aatctagctg
    35521 tcgcagctgc caaagaatta gctagtaaag gcgaaaaagt ccgcgtagtc agcatgccat
    35581 ctacagatgt ctttgataaa caagatgcag cttacaagga agagattctt ccaaatgcag
    35641 tccgccgtcg tgttgcagtc gaaatgggtg caagtcaaaa ctggtacaaa tatgttggtc
    35701 tcgatggtgc cgttctaggt attgatacct tcggagcctc tgccccagca ccaaaagtat
    35761 tggcagaata tggctttact gtagaaaatc ttgtaaaagt tgttcgaaac ttgaaacaat
    35821 cctaaaaatc agggcgtaag ctctggtttt tcttaccaga aaagtaaggt acaatcttgt
    35881 aaaagtagct gaaatttgat atagtagtcc tatgtaaaag acaaaggaga aaacaatgaa
    35941 tccaaatatt acttttttaa tcatgcttgt aggtatgatg gccttgatgt tctttatgca
    36001 acgctctcaa aagaaacaag cacaaaaacg tatggaaagc ttaaataaac tacaaaaagg
    36061 ctatgaagtg attacaatcg gtggacttta tggaacagtc gatgaagtag atacggagaa
    36121 gggaacaata gttcttgacg tagatggagt ttacttgact tttgaactag ctgctatcaa
    36181 gacagtatta ccgctgaaag aaacagcttc actagaaggc gcaattgaaa aataagacgg
    36241 gatcacgaac tcccgttttt ctataaaaga aaggaaatgg gatgaaaaaa ttagtctttg
    36301 tctgtctggg aaatatttgc cgtagcccta tggccgagtt tgttatgaaa tcaatgacag
    36361 ataactacga aatccaaagt cgagcaactt cctcttggga acatggcaat ccgattcata
    36421 aggggactca gggaattttt caagagtatg agattcctta tgacaagaac aagacatcgc
    36481 ttcagattag taaggaagat tttgaagcct ttgattatat tatcggaatg gacgcttcaa
    36541 atgtttccga cttacgtcag atgtgtccag tagactgtca agataagatt tactcatttt
    36601 catctgaaag tgttccagac ccttggtata caggagattt tgaagaaacc tatcgacgtg
    36661 ttcaagaggg ctgtcaagct tggttagaac gtttagaaaa ggagagttaa ggtggaaaat
    36721 cttacgaatt tttacgaaaa gtatcgtgtc tatctgactc gtccacgttt agagcttttg
    36781 gcagtagtta ccattgtttt ctgtgctgta ctcgtctttt ttctaaatat tccaggaaaa
    36841 ggtgtcttaa aactcgataa tggaacgatt gtttatgatg gcagtcttgt ccgtggtaaa
    36901 atgaatggcc aaggtaccat taccttccaa aatggagacc aatatacagg tggcttcaac
    36961 aatggagcct tcaacggaaa aggtaccttt caatctaaag aaggctggac ctacgaaggt
    37021 gattttgtaa atggtcaggc tgaaggaaaa gggaaactaa caacagaaca agaagtcgtt
    37081 tatgaaggaa cttttaaaca aggcgttttt caacaaaaat aaagcctcct tatcaaagga
    37141 ggtattatta gaattacaag gtaagcgttt acctgtaaat ccctttcttt ccaaatccct
    37201 cttccaagca agtttgtgaa ataaaaaata tttgaaataa atttcacaaa cttcaaagat
    37261 aaaacctgat aagaaaagaa aatgagaaaa gtttcacaag agtttaaaaa ttctttgtga
    37321 aatgtttatg aaactgttta caaagttgaa ataatgcgtt ataataaact tgtgaaaaaa
    37381 ttaacaaagg atatcgttcc ttgaaagcta tggaggaaaa tatggctgat aaaaaaactg
    37441 tgacaccaga ggaaaagaaa ctcgttgctg aaaaacacgt agatgagttg gttcaaaaag
    37501 ctctagttgc ccttgaagaa atgcgtaaat tggatcaaga gcaagttgac tacatcgttg
    37561 ccaaagcatc agtagcagct ttggatgccc acggagaatt ggctttacat gcctttgaag
    37621 aaacaggacg tggtgtattt gaagataaag caactaagaa cttgtttgcc tgtgaacacg
    37681 tagtaaacaa catgcgccac actaagacag ttggcgttat cgaagaagac gatgtaacag
    37741 gattgactct tattgctgaa ccagttggtg ttgtttgtgg tattactcca acaacaaacc
    37801 caacatcaac agcaatcttc aaatcattga tttcattgaa gacacgtaac ccaatcgtct
    37861 ttgccttcca tccatcagca caagaatcat ctgctcatgc agctcgtatc gtccgcgatg
    37921 cagctatcgc agctggtgct cctgaaaact gtgtgcaatg gattactcaa ccatctatgg
    37981 aagcaacaag tgcccttatg aaccacgaag gtgttgcgac aatccttgca acaggtggta
    38041 atgccatggt taaggcggct tattcatgtg gtaaaccagc tcttggggta ggtgccggaa
    38101 acgttccagc ttatgttgaa aaatcagcaa acattcgtca agcagcacac gatatcgtca
    38161 tgtctaaatc atttgataac ggtatggtct gtgcatctga acaagcagtt atcattgata
    38221 aagaaattta cgatgaattt gtagcagagt tcaaatctta ccacacttac tttgtaaaca
    38281 aaaaagaaaa agctcttctt gaagagttct gcttcggcgt caaagcaaac agcaaaaact
    38341 gtgctggtgc aaaattgaac gctgacatcg ttggtaaacc agcaacttgg attgcagaac
    38401 aagcaggatt tacagttcca gaaggaacaa acattcttgc tgcagaatgt aaagaagttg
    38461 gcgaaaatga gccattgact cgtgaaaaat tgtcaccagt tattgcagtt ttgaaatctg
    38521 aaagccgtga agatggtatt actaaggctc gtcaaatggt tgaatttaac ggtcttggac
    38581 actcagcagc tatccacaca gctgacgaag aattgactaa agaatttggt aaagctgtta
    38641 aagctattcg tgttatctgt aactcacctt ctacttttgg tggtatcggg gacgtttaca
    38701 atgccttctt gccatcattg acacttggat gtggttctta cggacgcaac tcagttgggg
    38761 ataacgttag tgccattaac ctcttgaata tcaaaaaagt cggaagacgg agaaataaca
    38821 tgcaatggat gaaacttcct tcaaaaacat actttgaacg tgattcaatt caataccttc
    38881 aaaaatgtcg tgacgttgaa cgtgtcatga tcgttactga ccatgccatg gtagagcttg
    38941 gtttccttga tcgtatcatc gaacaactgg accttcgtcg caataaggtt gtttaccaaa
    39001 tctttgcgga tgtagaaccg gatccagata tcacaactgt aaaccgtggt actgagatta
    39061 tgcgtgcctt caaaccagat accatcatcg cactcggtgg tgggtctcca atggatgctg
    39121 ccaaagtaat gtggctcttc tacgagcaac cagaagtgga cttccgtgac cttgtccaaa
    39181 aattcatgga tatccgtaaa cgtgccttca agttcccatt gcttggtaag aagactaaat
    39241 tcatcgcgat tccaactaca tctggtacag gatctgaagt aacaccattt gccgttatct
    39301 ctgataaagc aaacaaccgt aaatacccaa tcgctgacta ctcattgaca ccaactgtgg
    39361 caatcgtaga tcctgctttg gtattgacag ttccaggatt tgttgctgct gatactggta
    39421 tggacgtatt gactcacgcg acagaagcat acgtatcaca aatggctagt gactacactg
    39481 atggtttagc acttcaagcc attaaattgg tctttgaaaa tctcgaaagc tcagttaaga
    39541 atgctgactt ccactcacgt gagaaaatgc ataacgcttc aacaatcgct ggtatggcct
    39601 ttgccaatgc cttcctaggt atttctcact caatggccca taagattggt gcgcaattcc
    39661 acacaatcca cggtcgtaca aatgctatct tgcttccata cgttatccgt tacaacggta
    39721 cacgtccagc taagacagca acatggccta agtacaacta ctaccgtgca gatgaaaaat
    39781 accaagatat cgcacgcatg cttggacttc cagcttctac tccagaagaa ggggttgaat
    39841 cttacgcaaa agctgtctac gaactcggtg aacgtattgg gatccaaatg aattttagag
    39901 accaaggaat tgacgaaaaa gaatggaaag aacattctcg tgaattagcc ttcctggctt
    39961 atgaagacca atgttcacca gctaacccac gtcttccaat ggtagaccat atgcaagaaa
    40021 tcatcgaaga tgcatactat ggctacaaag aaagaccagg acgccgtaaa taattgttta
    40081 tcagtctaga agcaagacaa aaactcaatt tgagggaaag atccagtaat ttttctatga
    40141 taaaaggcat cctatcaagg tttttgaaca cctgatagga tgccttttta tgatattgag
    40201 gcctttttgc cctttttgaa aaactagaat agaaacaaaa tatgtaatag attgaaacta
    40261 gaatagtaca catctgcttc taaaacattt atagaaatta attttacttt cctgatagag
    40321 ttgttcacat cttatttcaa ttcactatag tttaatttaa gagtagtatt tactaaggcc
    40381 caattaaaat caaagagcaa actagaaaac gagtgccatt cagctcaaaa cactgatttg
    40441 agattgcaga taagactagc cccctcatta acagatttac gataaaacga tgacaaggtg
    40501 tgttgctttt tgatttctaa agagtataat gatagatctc tataaaataa gtgcgaagga
    40561 aatgagcttt tatagtcctt tcgttttaaa atactatctc agatattctt atatcgacaa
    40621 gaagtttttg agtcattccc tcatcataca tattaaataa atagtggctc attcaatttt
    40681 tcactagaat aataagctag tatagtaaac tgaaataaga tataaacaaa taaattggag
    40741 cttaacatcc atttccagca attttttaga aactacagtg gactattcta gattcaacat
    40801 attataaaaa ctagagtaaa agaaaaggat tggatcttgt gtaatgcagg atccaatcct
    40861 ttcaatcatt ttgtccaact tttggaggtt cctacaatgt agtcgtcatt aataaagaca
    40921 gatgggaatg acagtgttcc tatttatttt gatagagatc gatgaattct ttagatagca
    40981 actgaataat ctctgttgaa gccatttggt cttctgcatg cataaatagc aaggagaatc
    41041 ctattttttc tccagtagct tctttttgta tgagattaga gtgaatcttg tgcgcttcta
    41101 ctaaggagtc ttccgcttct tcaactttaa ttttcgcttc ttttaaattt cctgccttag
    41161 ctagttggat ggcttcaata aaggatgatt tggctgctcc actattggca atgagctgaa
    41221 aacagatata ttccatttct tctgtcatct tatttctcct atccattcaa gtgcttgttc
    41281 cagaactttt gctccattca tcattccgta atcccgcata tcaatggtat ctacagggat
    41341 atttcctgca atttctttca cagcaagtaa ctcataacga atttgtggcc caattagaat
    41401 gacatctgct tcatggatat tctttttagc ttctgtcatt gattttgctt ggatagaaat
    41461 ttcaatccca cgttcagtcg cactttgttg cattttttta acaagcatac ttgtcgacat
    41521 tcccgcatta catactaata aaatttgttt cataatctta accttccatt tcttgttcaa
    41581 caactttgtc attaactttg ataaatggaa tgtatagaag aactccaagt gcaaagatga
    41641 tgaattgaac tagaactgct ctcacgtccc ctgctgttgc taaccatgca tttaagaata
    41701 ctggtgtagt ccaaggaact tgtataaatg caggactcat gaatcctgta actgttgcta
    41761 agtagctgat taaaatacca aggactggaa ctgtgataaa tggaatagct aatgaaatgt
    41821 tataaacgat tgggtaaccg aataatactg gttcattgat attgaagata ccaggtccaa
    41881 aagataattt agccacgttt ttagaaacag cattgcgact tactaagaat gttgctatta
    41941 ataaacataa tgtagatcca ctaccaccca ttaaagcgaa tgtttgtatt tgtgataggt
    42001 tgatgatgtg tggaatggct tgtccattat ttgctgcagt gatgttttca gtaatgttaa
    42061 ttaatagtaa tggttctagg atggcactgt aaataactgc ttggtgaata ccaaatagcc
    42121 ataacatatt tcctaaagag taaataataa tgaccccgat taagcttgta ccaatatgac
    42181 gaattggttc ttgaataaag attgtaatga ttgagattaa gttcattcca gttatattga
    42241 ataataatgc tgaaacaacc ccaaataagg agatgacggt catgactgga agtaatacgc
    42301 taaatgatct actaacagct ggtggaatat tttcaccaag gttcatttgt aaagctttaa
    42361 catttgataa ttcaatgaat aattctgttg caataatcgc tacgataacc ccggcgaaca
    42421 ttgcgcctgt acctgtgttg ttgaatgaaa gaacacctga aatgtttaca gcatcttttg
    42481 ctccgtcagg aactacagaa actgtatttg gcatcatcac aattaaagaa actaatgata
    42541 gcattgatgc tgctaacggg ttttcgaaat ctctgttttt agctaagaaa taaccaacca
    42601 ttacagcaat aatcatacct gaaatactta aagtaccgtt tgcaattgtt attccccaat
    42661 attggaatct tgttaatgta tccccttgga aaatccactt aaataccgtg ttgttcaaaa
    42721 gaacgattaa acctgccaaa atatataatg gcattactgt tacgaatgca tctcttagag
    42781 tttttaaatg aatttggttc cctagtttac cagcaaaggt ggcaaattga tctataaatt
    42841 ttgagttttt catctgaata tctcctctct ttactcctca atttctactt caaaaccgtt
    42901 attgtcactt actttgcgat accatcttcc tgagctcttg atggttctct tttgcgtttc
    42961 taaatcaacg gagataaatc cgtaacgatt cttatatgca ttattccaag accagcaatc
    43021 aaatgcggtc caagcgtggt atccaaaaca gtgacttccc tcttcaatgg ctttatgtag
    43081 ccatcttaaa tgttcttcat aaaattcaat acgatacacg tcatcgataa ctccattttc
    43141 accgataaac cgtgcttcgt tttcaacacc cattccgttt tcactgataa accatggaat
    43201 attatcatat tcttccttca caatcatagc aatatcataa atggctttcg gaaaaatttc
    43261 ccaaccacga tatggattca tgcgacgctc cggccattca tactctttga agtattggtc
    43321 tggcatccag ggcgtctgat attcctcagg atttgcttgt gcttgaacac gttttggatg
    43381 gtagtagttt actccaagaa aatcaaccgt atttgatttc atcagttgaa gctctttttc
    43441 ggtatgactc cataacacgc catctctctc tagctgtttt accaatcttt ctgggaaagt
    43501 tcctttaaca gctggattca agaagacttt gttaaagaag tcatctgtaa atcgacttgc
    43561 ttctaagtct tctggagaat tacttcttgg ataagcaggt gtcaagttta aaataatccc
    43621 aatctttcca tcaagtccta atgagcgata tagttgaatc acttttgcac tagcaaggtt
    43681 tagattatag atgacttgta cggcctcttt tccctttcct tttagatttg gataatggaa
    43741 agcatataag tatcctgctt ctggaatgac cattggctca ttgaaagttg tccagtaatg
    43801 aaccttatct ccaaagcatg ttaaagcagt cttggcaaac ttcacgaata actccactac
    43861 atgtttgctt tcccaaccac cgtatttttg aagaagttcc actggtaaat caaaatgatg
    43921 taaattcatc acaagatcca tctggttctt tttagcttct tcaatgatgg cattgtagaa
    43981 agcaatacct tttggatcag gctcacctgt ctctaaattc ttgatgagtc gactccattg
    44041 gatggaagtg cggaaagaat taactccaat ttccttcatc aagtggaaat cttcggtgta
    44101 agtatgaaaa aagttactgg ctacaagagg tccgacatta tcgaaaaaat cttctggatg
    44161 cgttttgaac cagtagtcca tcacattttc atgtactttt ccatattgac cttctgtctg
    44221 aggtccgcta gaagcagctc cccaccaaaa cagattagga aatactaact tttttttcat
    44281 gctcaacctc ctttctatta ttctatacat aaagtatagc ataattttaa aatttgtcta
    44341 gacattttta aaaattgttg atacatatct tgtgtttgcc tcatttcttg aactttgtta
    44401 tactactatt agaatattat agagagaacc agattaaatg agtacaaaat atttatttat
    44461 ttacaatgag attcgtgaaa agattctttg taataaatat accatgaacg aacaattgcc
    44521 tgatgaaatg acattagcta aacagtttgc ctgtagtcga atgacgatca aaaaagcttt
    44581 agacttgtta gtttctgagg gcttaatttt tagaaaacgt gggcagggaa cctttgttct
    44641 ctctcgtggc agctcaaaaa gaaaattaat cgttccagaa agagatatcc ggggactgac
    44701 aaaaatatct gaagatgctc attctacaat tgactcgagg attattcact tcaaattaga
    44761 atttgcaaat gaatttttag cagaaaaact acaggtcgct ttgcagagtc cagtttataa
    44821 tatttaccgc ctgcgtatta ttgacggtaa accttatgtt ctggaacaaa cttatatgag
    44881 taccgatgtt attccaggta ttactgaaga tattttacaa aaatcgattt acaattacat
    44941 tgaaggaaaa ttaggattgc atattgccag tgctacaaaa atcttacgag cttcttctag
    45001 ttcagaaaat gagcaacatt acttgcagct ccttccaacg gaaccggtat ttgaagtaga
    45061 acaagtggct tatttggata acggaactcc gtttgagtac tcgattagtc gtcatcgcta
    45121 tgatttattt gaatttaatt cttttgcatt acgacattcc tcctaggaga aaatgtgaaa
    45181 atgaagccaa tcttttacag actctagttt aagaaaaatt taaaacaggg caagaaggtc
    45241 ccatctatgc ttaaatggtt tctcttttct aaataagatg gctttaaaag agtgatcgtt
    45301 ttatccatca tgttgaaaaa tatcttcgta tagcttatag agtaggtact gaaattgttc
    45361 gcctgatcta cttcttatag ttatttagtt ttaaatagtg tttcaaacat tcttacactg
    45421 acgagaagtt tttgagtctt ttcttgtaac acatatagta tactgaggtt agaatagtag
    45481 actgtgactt ctaacaaatt gctagaaatg aatttcaatc tcccaattta tttgttcata
    45541 tcttctttta atatattaaa taaattctga atcataatca tttaaaaaaa ttttattttt
    45601 ttatttttca ttacgaataa tatagatgaa ggggaaagag tatgaaaaca gaactgtttc
    45661 ttttgctatt agttcaaaag gagaaaaaat gaaagtagaa aatatttcgt atagggtgga
    45721 tcatcgtata ttgtttgata atatttcttt tgatacttcg agttcaggcg tgacattaat
    45781 tactggtaaa aatggtacag gaaagtcaac tttactatag tagattgaaa ctagaatagt
    45841 acacatctac ttctaaaata ttgttagaaa tcgatttgac tatcctgatc tatttgtcct
    45901 gttcttattt catttcacta tatctcaaat tgagtatgac gaagtgcgct cccatgtcct
    45961 gggaacgcac tttcttcata tttttcatat tcttgaatcc atcgataaag actattggga
    46021 tgaattttta aagttgaact aatcattttt acaggatgag gtttacagca gagagtttga
    46081 aggctttatc aaaggttttt cttggcataa tgacttttcc tcgtttccac ttaattttgt
    46141 gtctacttta ttataccaag tccaccctta agttagataa taaatctaac ttaaggaagc
    46201 tagaaggatg agaatccagg tggtcaagag tcccaaactt aagctgatgg ggacacccag
    46261 aataatttgc tttttgaagg caaggccacg ttcctctata ttgggaagtg agagttgaat
    46321 gagagaacca gctgatgaaa agggtgagat attagtagat agagcgccaa taacggtggc
    46381 tgttgtgagt aagtgaatat caatctgggg attttgagca ctgatgatag caatgatggg
    46441 aaagagggct ggagctacaa cggatagggt ggaactaaag agtgacatca ctccggctat
    46501 cacacaaaag aacagaggta accagaaatg aggaatggat gttgtcatga ggtgccctat
    46561 cagtgtgact aaacctgact tgaccgctag agacattagt aagctcatgc cgcagagcat
    46621 gataattgta gcccagggaa ctttagccaa aatggcttct tgcttcccta atttgagcct
    46681 taaggcgagg cagaccatga gtattgagac aaagccaata tcaaatgttt ttcgataagt
    46741 agctatccag gcgatgtttg ggaaaatgag atgcaacaag ggaaaaagcc aaaccaaaac
    46801 catgctgctg atcatgagta aggtggtttg tctttgaacc ttgctgagga gtggtggttg
    46861 gtcaatagtc aaggatgagt ttgttcttcc cttgctatag tgactgtaac aggataataa
    46921 aagcaagacg atgagtgggt agataatgct gacgataaag atatgattgc caagtgaaaa
    46981 agcttgctct tcccatccca tttgcttaaa caggccttga aagacaatgc ctgagctact
    47041 ggttatcaaa ttagcccctc ctgaagctcc ccaattgacg gcttgagctc caatcaaagg
    47101 gtgtttgtcc gctttttgac agagggtaat cgctagagga cagcaaacgg ccatagtagt
    47161 gaaaaatcca gcacctaaag cagacaaaag ggttgccatc aggtataaaa tcatgtagag
    47221 ggcgttaggg taggtgcgtg tgcggtagag aatgtgttga gccaaaacat caagagtacc
    47281 gttagttatt gcaaagttat aaaagagaga gacgctaaaa atggtaaaaa agagtgaggt
    47341 tggccaaaaa tgaagaagtt ctttggggct taatcccatg agagtggttg cgatgaggta
    47401 agaaaaagca atagccagca ggccaatatt gattttggtg cggtaaccaa ttccaatggc
    47461 tagagcaatg gcgctaatca ttattaaatg aatcattgaa ttgtcctttc agttagaata
    47521 tggaaatagg ttggcaattt tggcgctcaa aagaccacct gtttcctatt ggtacttgac
    47581 tattatacac aaaaaaaata caattgtatt gacaattgta ttgacaattg ttagaattaa
    47641 aaatgaggta ttcaggcttg tgattttcta tggaagttaa tagtgattgc ctctaatgct
    47701 tacaagtgat attaaaaata gaggacctag tgatgtcaat catttcaact gatttaaccc
    47761 cttttcaaat agatgataca ttgaaagcag ccttgcgaga agatgttcat tccgaagatt
    47821 acagtaccaa tgccattttt gatcatcatg gccaagccaa ggtgtcgctt tttgccaagg
    47881 aagctggtgt tttagcgggg ctaaccgttt ttcaaagggt ttttacccta tttgatgccg
    47941 aggtgacctt ccagaatcct catcaattta aggatgggga tcgtttgact agtggcgatt
    48001 tggttttaga aatcataggc tcggtgagaa gtctcttaac atgtgaacgc gttgccttga
    48061 attttttaca acatttatca gggatcgctt cgatgacagc tgcttatgta gaagccttag
    48121 gcgatgattg cattaaggta tttgatactc gaaaaactac tcctaattta cgtctttttg
    48181 agaaatatgc cgtgagagtt ggcggtggct ataatcatcg ctttaattta tcagatgcta
    48241 tcctgctaaa agacaatcac attgcggcag taggtagtgt tcaaagggca attgctcaag
    48301 cgcgtgccta tgctcctttt gtgaaaatgg tcgaggtgga agtggaaagc cttgctgctg
    48361 ccgaagaagc tgcggcggcg ggtgctgata ttatcatgtt ggataatatg tcattggaac
    48421 agattgaaca ggccattacc ctaattgcag gacgttctcg gattgaatgt tctggaaata
    48481 ttgatatgac cactattagc cgttttcgtg gtttagcgat tgattacgtc tccagtggta
    48541 gtttaaccca tagtgctaag agtcttgatt tttccatgaa gggtttaacc taccttgatg
    48601 tctaagttgt aaaataaact aactttttaa aggatgtctt tcctctagaa cgagttttat
    48661 gtcagatagt ttaaacgcct cttcaaatat agtaaaatga accaaaaata gtacacaatg
    48721 tggtataatc ttcttatggc atattcaata gattttcgta aaaaagttct ttcttattgt
    48781 gagcgaacag gtagtataac agaagcatca cacgttttcc aaatctcacg taataccatt
    48841 tatggctggt taaagctaaa agagaaaaca ggagagctaa accaccaagt aaaaggaaca
    48901 aaaccaagaa aggttgatag agatagactt aaaaactatc ttactgacaa tccagacgct
    48961 tatttgactg aaatagcttc tgaatttggc tgtcatccaa ctaccatcca ctatgcgctc
    49021 aaagctatgg gctacactcg aaaaaaagaa ccacacctac tatgaacaag acccagaaaa
    49081 agtagcctta tttcttaaaa attttaatag tttaaagcac ctagcacctg tttagattga
    49141 tgaaacagga ttcgatactt atttttatcg agaatatggt cgctcattaa aaggtcagtt
    49201 aataagaggt aaagtatctg gaagaagata tcagaggatt tctttggttg caggtctaac
    49261 aaatggtgag ttaatcgctc caatgactta cgaagagacg atgacgagcg acttttttga
    49321 agcatggttt cagaagtttc tcttaccaac attaaccaca ccatcggtta ttattatgga
    49381 taatgcaaga ttccatagaa tgggtaagtt agaactttta tgcgaggagt ttgggcataa
    49441 acttttacct cttcctccct actcacctga gtacaatcct attgagaaaa catgggctca
    49501 tatcaaaaag cacctcaaaa aggtattacc aagttgcaat accttttatg aggctctttt
    49561 gtcctgctct tgtttcaatt gactatagtt cacggataca gttgggaaag aagctattaa
    49621 atatttggag agtccttttg ggatgaacat gtcaaatatt actatagatg ggcaagaaaa
    49681 gatgggcaag aaatggattt gagtcaaacg atgcttctta tgctcaagta gtgagtcttt
    49741 atgatgatac aagtatctct gttagtaata atgagacgga caaagtgttg gctggatccc
    49801 tctatactga tacaaatgaa cagggattaa cgattccaag cagtttacta aaaaattgga
    49861 atgaacagac aggaaaaaat ttgacagcta atgatcttat tggcaaatca gtctcagtca
    49921 gcattgtaga aagtgctgcc gaaactagta agattgctca atttcaaacg aagattgtac
    49981 gtgtaatcaa tgatgaagat gacatggagg acagcaacag tttcatgctg tctcatcaaa
    50041 tggaaacgat tttgaaagag gctggattta cgaaagctgt atcttatttt atcttggaac
    50101 tcaaagatcc atcacagaca aaagtagtaa cagaagaatt acagaaaaat aagaagtata
    50161 ctgtgctttc ttaacagaga gttcttgata ttgtgattac ctttattcgt gttattcagg
    50221 gattattgat tgtgctttca tcacaagcta ttgtggtagc agcggttatg attggtatca
    50281 ttatttacat caatatcatg caacgttcca aggaaatagg tgtcatgaaa gcagttggtt
    50341 atcagaatcg tgatgtcaaa ggaattttta tttacgaggc tatctggatt gtaggcatcg
    50401 ccttgctgct ggcatttttg gttgcacaag gggtgggaag tttggcgaat gcgattgtaa
    50461 gtcactttta cccatccatc actaaggttt ttgaattaaa tcttttatct gttttaggaa
    50521 ctctagtttt cgctctatta cttggttatg tctcagccta cttcccggcg cgtaagatta
    50581 gtaaaatgga tcctgtagaa tcgttacgct atgaatagta agggattcct tgatttacag
    50641 tcttaaaaag aaactaacat agaaaaacaa tggccatact tgcaattcaa ctcaaatagt
    50701 tgtataatag gtttgttgaa aggtgatttg tagtgattca agttactctt ttcacaataa
    50761 aaatttcatg attttcataa ggaggaaatc actaatggta gttaaagttg gtattaacgg
    50821 tttcggacgt atcggtcgtc ttgctttccg tcgtatccaa aacgtagaag gtgttgaagt
    50881 tacacgcatc aacgacctta cagatccagt tatgcttgca cacttgttga aatacgacac
    50941 aactcaaggt cgtttcgacg gtactgttga agttaaagaa ggtggatttg aagttaacgg
    51001 taaattcatc aaagtttctg ctgaacgtga tccagaacaa atcgactggg ctactgacgg
    51061 tgtagaaatc gttcttgaag ctactggttt ctttgctaag aaagaagcag ctgaaaaaca
    51121 ccttaaaggt ggagctaaaa aagttgttat cactgctcct ggtggaaacg acgttaaaac
    51181 agttgtattc aacactaacc acgacgttct tgacggtact gaaacagtta tctcaggtgc
    51241 ttcatgtact acaaactgct tggctccaat ggctaaagct cttcaagaca actttggtgt
    51301 tgttgaagga ttgatgacta ctatccacgc ttacactggt gaccaaatga tccttgacgg
    51361 accacaccgt ggtggtgacc ttcgccgtgc tcgcgctggt gctgcaaaca tcgttcctaa
    51421 ctcaactggt gctgcaaaag ctatcggtct tgtaatccca gaattgaatg gtaaacttga
    51481 tggatctgca caacgcgttc caactccaac tggatcagtt actgaattgg tagcagttct
    51541 tgaaaagaac gttactgttg atgaagtgaa cgcagctatg aaagcagctt caaacgaatc
    51601 atacggttac acagaagatc caatcgtatc ttcagatatc gtaggtatgt cttacggttc
    51661 attgtttgac gcaactcaaa ctaaagttct tgacgttgac ggtaaacaat tggttaaagt
    51721 tgtatcatgg tacgacaacg aaatgtcata cactgcacaa cttgttcgta ctcttgaata
    51781 cttcgcaaag attgctaaat aattcttgag ttgatagaaa gcaaggcttt gtggtcttgc
    51841 ttttttatat ggaaaaatgg atgacacgat catccattct tttttaattc tttttcaaat
    51901 gtatttgaaa gggtagtgaa agttagcttc tctaaagtaa gtgggtgggt aaaggaaagt
    51961 cggaaggcat gaagcataag ccgacttgtc tttgatttac tattatagag agggtcgccc
    52021 aggataggaa gattatgatg cgaaaggtgc acacgaatct gatgggttcg ccctgtcttt
    52081 agcttgcaac gagccaagga agtcttgttt gagaattgct ttaatctgct tacatgcgtt
    52141 tcagcatatt gcccattttt tgcatcaact attctttttc tacgatcatg gcgatcacgt
    52201 ccaattttgt ctctgaaaac aagttctttt ctgttgatat ttccatcaac tagagcccaa
    52261 tattctctag aaatctcttt tttctccaat aagcgattga gaatgggcag gataaaagga
    52321 tttttggcaa agagaactaa gccactggtt tccatgtcca gacgatgaac gacatagcag
    52381 gtttggccaa cataggtact gacatggtta agaagggcaa tttcgtttgg ttgattacca
    52441 tgcgttttca tcccctctgg tttgtttaca ataatcaagt gttgatcttg ataaacttcc
    52501 tgcactaagt ctgggttgcc ccaagggatc gtcttttggg gataatcttc ctcgtcaaaa
    52561 gtcaactggc aaacatctcc aggatttacg atttccttcc agtggacttc ttcttgattt
    52621 atcaaaatat gtttcttgat tctcaaaaaa tgacggattt ttctagggat gaggagttgt
    52681 tcctcaagta attgctttac cgtcatttga ggtagagagg cgggtaatgt aaatgtgaat
    52741 tgcatacaga tattgtaaca aaaaaagccc tatttggata ggaaatagct aaattcttgt
    52801 cttcctatga tgaagatgat aaaataaacg catgaaatta gataaattat ttgagaaatt
    52861 tctttctctt tttaaaaaag aaacaagtga actagaggac tctgattcta ctatcttacg
    52921 tcgctctcgt agtgatcgaa aaaaattagc ccaagtaggt ccgattcgaa aattctggcg
    52981 tcgttatcat ctaacaaaga ttatccttat actaggtttg agtgcaggct tgctagttgg
    53041 aatctatttg tttgctgtag ccaagtcgac caatgtcaat gatttgcaaa atgccttgaa
    53101 aactcggact cttatttttg atcgtgaaga aaaagaggct ggtgccttgt ctggtcaaaa
    53161 gggaacctat gttgagctga ctgatatcag taaaaacttg cagaatgctg ttattgcgac
    53221 agaagaccgt tctttctata aaaatgacgg gattaactat ggccgtttct tcttggctat
    53281 tgtcactgct ggacgttcag gtggtggctc taccattacc caacagctgg ctaaaaacgc
    53341 ctatttatca caagatcaaa ctgttgagag aaaagcgaaa gaatttttcc ttgccttaga
    53401 attaagcaaa aaatatagta aggagcaaat tctaaccatg taccttaaca acgcttattt
    53461 tggaaatggt gtgtggggtg tagaagatgc gagtaagaaa tactttggag tttctgcatc
    53521 agaagtgagt ctggatcaag ctgcgactct ggcagggatg ctcaaggggc cggaactgta
    53581 taatcccttg aattccgtag aagattctac taatcggcgc gatactgtct tgcagaatat
    53641 ggttgcagca ggatatattg ataaaaacca agaaaccgaa gctgctgaag ttgatatgac
    53701 ttcgcaattg cacgataagt atgaaggaaa aatctcagat taccgttacc cctcttattt
    53761 tgatgcggtg gttaatgaag ctgtttccaa gtataatcta acagaggaag agattgtcaa
    53821 taatggctac cgcatttaca cagagctgga ccaaaactac caagcaaata tgcagattgt
    53881 ttatgaaaac acatcgctat ttccgagggc agaggatgga acgtttgctc aatcaggaag
    53941 tgtagctctc gaaccgaaaa cagggggagt tcgtggagtt gtcggtcaag ttgctgacaa
    54001 tgataaaact ggattccgga atttcaacta tgcaacccaa tcaaagcgta gtcctggttc
    54061 tacaattaag cctttagttg tttatacgcc agcagttgaa gcaggctggg ctttgaataa
    54121 gcagttggat aaccatacca tgcagtatga cagctataag gttgataact atgcagggat
    54181 caaaacgagt cgagaagttc ctatgtatca agccttggca gaatcgctta atctacctgc
    54241 tgttgccact gttaatgatt tgggtgtcga caaggctttt gaggcaggcg aaaaattcgg
    54301 actcaacatg gaaaaggtcg accgtgttct tggtgtcgcc ttgggaagcg gtgttgaaac
    54361 caaccctctt caaatggctc aagcatacgc tgcctttgca aatgaaggtt taatgcctga
    54421 agctcatttt attagtagaa ttgaaaatgc tagtggacaa gttattgcga gtcataaaaa
    54481 ttcacaaaaa cgggtgattg ataagtctgt agctgacaag atgaccagta tgatgttggg
    54541 gactttcacc aacggtaccg gtattagttc atcgcctgca gactatatta tggcagggaa
    54601 aactggaaca actgaagcag tttttaatcc ggagtacaca agtgaccagt gggtaattgg
    54661 ttatactccg gatgtagtga ttagccactg gcttggcttt ccgaccactg atgaaaatca
    54721 ctatctagct ggctctactt caaacggtgc agctcatgtc tttagaaaca ttgccaatac
    54781 cattttaccc tatacgccag gaagtacctt tacggttgaa aatgcttata agcaaaatgg
    54841 aattgcacca gccaatacaa aaagacaagt acaaaccaat gataatagcc agacagatga
    54901 taatttgtct gatattcgag ggcgtgcgca aagtctagta gatgaggcta gccgggctat
    54961 ctcagatgcg aagattaagg aaaaggctca aacaatatgg gattcgatag tcaatctatt
    55021 tcgctaagat gcttgtcaaa gcctagcttt cttgttataa tggataagat ggaggcgtta
    55081 tggcactaaa aaaagcaagc ctagcttgtg cggtttgtgg ttcgagaaac tattcaatca
    55141 agatcagcgg aaaccccaag cctacacgac tagaagtaaa taaattttgt aagcattgtg
    55201 gcaagtacac tacacataga gaaacgagat aggagagagc gatgcgtttt attggagata
    55261 tttttagact tcttaaagac acaacgtggc caactcgcaa ggaaagctgg agagattttc
    55321 gttctatcat ggaatacaca gctttctttg tagtaattat ttacattttt gaccagttga
    55381 ttgtttcagg tttgattcga tttattaaca ttttttagaa gattagtgga gttaattaca
    55441 ctagaaatct tctatttatg aaaggaaata tcatggatag ttttgataaa ggatggtttg
    55501 ttttacaaac ttattctggt tatgaaaata aggtgaaaga aaatctatta caacgtgcac
    55561 aaacctacaa tatgttggat aatattctac gcgttgaaat tccaacacaa acagtgcaag
    55621 ttgaaaaaaa tggaaagaga aaagaagtag aagaaaatcg ctttccaggt tatgttcttg
    55681 tagaaatggt catgacagat gaagcttggt ttgttgttcg aaacacacca aatgttacag
    55741 gatttgtcgg atcacacggg aacagatcaa aaccaactcc attattggaa caagaaattc
    55801 gtgacatttt ggtatctatg ggacaaactg ttcaagaatt tgatttcgat gttgagattg
    55861 gtcaaactgt acgtattatt gatggtgctt ttgcagacta cactggtaag attacagaaa
    55921 ttgataataa caaagtgaaa atgattatct ctatgtttgg taatgacaca gttgcagaag
    55981 taaacctaaa ccaaatcgca gaattataac cctgagagag gctggagtct ctcttttttg
    56041 tgcagtttag gagctaaagg gaacagaatg gagaaaatgg aacaaatgtg ttttctaatc
    56101 tgttagactg tatctagaaa ggggaaaatt atgattaaag aattgtatga agaagtccaa
    56161 gggactgttt ataagtgtag aaatgaatat taccttcatt tatgggaatt gtcggattgg
    56221 gaccaagaag gcatgctctg cttacatgaa ttgattagta gagaagaagg actggtagac
    56281 gatattccac gtttaaggaa atatttcaaa accaagtttc gaaatcgaat tttagactat
    56341 atccgtaagc aggaaagtca gaagcgtaaa tacgataaag aaccctatga agaagtgggt
    56401 gagatcagtc atcgtataag tgaggggggt ctctggctag atgattatta tctctttcat
    56461 gaaacactaa gagattatag aaacaaacaa agtaaagaga aacaagaaga actagaacgc
    56521 gtcttaagca atgaacgatt tcgagggcgt caaagagtat taagagactt acgcattgtg
    56581 tttaaggagt ttactatccg tacccactag taag
//
LOCUS       DAVKAU010000008        56300 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVKAU010000008 DAVKAU010000000
VERSION     DAVKAU010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56300
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.008"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..261)
                     /locus_tag="VWX48_000558"
     CDS             complement(<1..261)
                     /locus_tag="VWX48_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9171228.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNRKIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSS"
     gene            968..2443
                     /locus_tag="VWX48_000559"
     CDS             968..2443
                     /locus_tag="VWX48_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU9171229.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(2409..3124)
                     /locus_tag="VWX48_000560"
                     /pseudo
     CDS             complement(2409..3124)
                     /locus_tag="VWX48_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3380..4240
                     /gene="speE"
                     /locus_tag="VWX48_000561"
     CDS             3380..4240
                     /gene="speE"
                     /locus_tag="VWX48_000561"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU9171230.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            4237..5496
                     /locus_tag="VWX48_000562"
     CDS             4237..5496
                     /locus_tag="VWX48_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU9171231.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            5496..6623
                     /gene="nspC"
                     /locus_tag="VWX48_000563"
     CDS             5496..6623
                     /gene="nspC"
                     /locus_tag="VWX48_000563"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU9171232.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6620..7705
                     /gene="aguA"
                     /locus_tag="VWX48_000564"
     CDS             6620..7705
                     /gene="aguA"
                     /locus_tag="VWX48_000564"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU9171233.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7715..8590
                     /gene="aguB"
                     /locus_tag="VWX48_000565"
     CDS             7715..8590
                     /gene="aguB"
                     /locus_tag="VWX48_000565"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU9171234.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8771..9580)
                     /locus_tag="VWX48_000566"
     CDS             complement(8771..9580)
                     /locus_tag="VWX48_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9171235.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            9853..10074
                     /locus_tag="VWX48_000567"
     CDS             9853..10074
                     /locus_tag="VWX48_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171236.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            10128..10799
                     /locus_tag="VWX48_000568"
     CDS             10128..10799
                     /locus_tag="VWX48_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9171237.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(10851..11039)
                     /locus_tag="VWX48_000569"
                     /pseudo
     CDS             complement(10851..11039)
                     /locus_tag="VWX48_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11032..11940
                     /locus_tag="VWX48_000570"
     CDS             11032..11940
                     /locus_tag="VWX48_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9171238.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKSQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11937..12398
                     /locus_tag="VWX48_000571"
     CDS             11937..12398
                     /locus_tag="VWX48_000571"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU9171239.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            12388..13275
                     /locus_tag="VWX48_000572"
     CDS             12388..13275
                     /locus_tag="VWX48_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9171240.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            13278..15161
                     /gene="cbpE"
                     /locus_tag="VWX48_000573"
                     /gene_synonym="pce"
     CDS             13278..15161
                     /gene="cbpE"
                     /locus_tag="VWX48_000573"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU9171241.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            15241..16371
                     /locus_tag="VWX48_000574"
     CDS             15241..16371
                     /locus_tag="VWX48_000574"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU9171242.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            16381..17643
                     /locus_tag="VWX48_000575"
     CDS             16381..17643
                     /locus_tag="VWX48_000575"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU9171243.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVAFPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            17647..18444
                     /gene="proC"
                     /locus_tag="VWX48_000576"
     CDS             17647..18444
                     /gene="proC"
                     /locus_tag="VWX48_000576"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU9171244.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            18664..19302
                     /locus_tag="VWX48_000577"
     CDS             18664..19302
                     /locus_tag="VWX48_000577"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU9171245.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            19299..20189
                     /locus_tag="VWX48_000578"
     CDS             19299..20189
                     /locus_tag="VWX48_000578"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU9171246.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQVNVSFQNAMEYLVLKEI"
     gene            20229..20546
                     /gene="yabA"
                     /locus_tag="VWX48_000579"
     CDS             20229..20546
                     /gene="yabA"
                     /locus_tag="VWX48_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU9171247.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            20549..21427
                     /gene="rsmI"
                     /locus_tag="VWX48_000580"
     CDS             20549..21427
                     /gene="rsmI"
                     /locus_tag="VWX48_000580"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU9171248.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEENQEND"
     gene            21614..22948
                     /gene="trmFO"
                     /locus_tag="VWX48_000581"
     CDS             21614..22948
                     /gene="trmFO"
                     /locus_tag="VWX48_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU9171249.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            23032..23769
                     /locus_tag="VWX48_000582"
     CDS             23032..23769
                     /locus_tag="VWX48_000582"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU9171250.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            23778..24335
                     /gene="frr"
                     /locus_tag="VWX48_000583"
     CDS             23778..24335
                     /gene="frr"
                     /locus_tag="VWX48_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU9171251.1"
                     /translation="MANIIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            24395..25249
                     /gene="cvfB"
                     /locus_tag="VWX48_000584"
     CDS             24395..25249
                     /gene="cvfB"
                     /locus_tag="VWX48_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU9171252.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            25258..25473
                     /locus_tag="VWX48_000585"
     CDS             25258..25473
                     /locus_tag="VWX48_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU9171253.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            25559..26527
                     /locus_tag="VWX48_000586"
     CDS             25559..26527
                     /locus_tag="VWX48_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU9171254.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(26505..26684)
                     /locus_tag="VWX48_000587"
     CDS             complement(26505..26684)
                     /locus_tag="VWX48_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171255.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            26720..27220
                     /locus_tag="VWX48_000588"
     CDS             26720..27220
                     /locus_tag="VWX48_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171256.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            27223..27483
                     /locus_tag="VWX48_000589"
                     /pseudo
     CDS             27223..27483
                     /locus_tag="VWX48_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(27850..28176)
                     /locus_tag="VWX48_000590"
     CDS             complement(27850..28176)
                     /locus_tag="VWX48_000590"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171257.1"
                     /translation="MVDVAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVT
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(28122..28535)
                     /locus_tag="VWX48_000591"
     CDS             complement(28122..28535)
                     /locus_tag="VWX48_000591"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU9171258.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(28536..28961)
                     /locus_tag="VWX48_000592"
     CDS             complement(28536..28961)
                     /locus_tag="VWX48_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU9171259.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            29138..29707
                     /locus_tag="VWX48_000593"
     CDS             29138..29707
                     /locus_tag="VWX48_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171260.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGKFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            29775..30425
                     /locus_tag="VWX48_000594"
     CDS             29775..30425
                     /locus_tag="VWX48_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU9171261.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            30409..32649
                     /locus_tag="VWX48_000595"
     CDS             30409..32649
                     /locus_tag="VWX48_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU9171262.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLQLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVVKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRSMTVGEYLPIFGSQLEVLSPRE
                     IGYGGHEDSLVLYGKLLNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            32828..33016
                     /locus_tag="VWX48_000596"
     CDS             32828..33016
                     /locus_tag="VWX48_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171263.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            33048..33635
                     /locus_tag="VWX48_000597"
     CDS             33048..33635
                     /locus_tag="VWX48_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171264.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            33639..34820
                     /locus_tag="VWX48_000598"
     CDS             33639..34820
                     /locus_tag="VWX48_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171265.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LRVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    34980..35111
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            35127..35657
                     /gene="infC"
                     /locus_tag="VWX48_000599"
     CDS             35127..35657
                     /gene="infC"
                     /locus_tag="VWX48_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU9171266.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            35690..35890
                     /gene="rpmI"
                     /locus_tag="VWX48_000600"
     CDS             35690..35890
                     /gene="rpmI"
                     /locus_tag="VWX48_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU9171267.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            35942..36301
                     /gene="rplT"
                     /locus_tag="VWX48_000601"
     CDS             35942..36301
                     /gene="rplT"
                     /locus_tag="VWX48_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU9171268.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            36359..36739
                     /locus_tag="VWX48_000602"
     CDS             36359..36739
                     /locus_tag="VWX48_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9171269.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            36989..37789
                     /locus_tag="VWX48_000603"
     CDS             36989..37789
                     /locus_tag="VWX48_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU9171270.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            37800..38738
                     /locus_tag="VWX48_000604"
     CDS             37800..38738
                     /locus_tag="VWX48_000604"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU9171271.1"
                     /translation="MTTNRLQVSLPGLDLKNPIISASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            38780..40813
                     /locus_tag="VWX48_000605"
     CDS             38780..40813
                     /locus_tag="VWX48_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU9171272.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGVKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDYHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDDFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(40874..42529)
                     /gene="pavA"
                     /locus_tag="VWX48_000606"
     CDS             complement(40874..42529)
                     /gene="pavA"
                     /locus_tag="VWX48_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU9171273.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQAGEPFANLSDLLDTYYKNKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            42634..43131
                     /gene="ybeY"
                     /locus_tag="VWX48_000607"
     CDS             42634..43131
                     /gene="ybeY"
                     /locus_tag="VWX48_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU9171274.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            43112..43507
                     /locus_tag="VWX48_000608"
     CDS             43112..43507
                     /locus_tag="VWX48_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU9171275.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            43524..44423
                     /gene="era"
                     /locus_tag="VWX48_000609"
     CDS             43524..44423
                     /gene="era"
                     /locus_tag="VWX48_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU9171276.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADLGYNEREY"
     gene            44472..45296
                     /gene="mutM"
                     /locus_tag="VWX48_000610"
     CDS             44472..45296
                     /gene="mutM"
                     /locus_tag="VWX48_000610"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU9171277.1"
                     /translation="MPELPEVETVCRSLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            45296..45901
                     /locus_tag="VWX48_000611"
     CDS             45296..45901
                     /locus_tag="VWX48_000611"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU9171278.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            45888..47087
                     /locus_tag="VWX48_000612"
     CDS             45888..47087
                     /locus_tag="VWX48_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU9171279.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            47087..47236
                     /gene="rpmG"
                     /locus_tag="VWX48_000613"
     CDS             47087..47236
                     /gene="rpmG"
                     /locus_tag="VWX48_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9171280.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            47276..47509
                     /gene="secG"
                     /locus_tag="VWX48_000614"
     CDS             47276..47509
                     /gene="secG"
                     /locus_tag="VWX48_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU9171281.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            47611..49965
                     /gene="rnr"
                     /locus_tag="VWX48_000615"
     CDS             47611..49965
                     /gene="rnr"
                     /locus_tag="VWX48_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU9171282.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            49928..50395
                     /gene="smpB"
                     /locus_tag="VWX48_000616"
     CDS             49928..50395
                     /gene="smpB"
                     /locus_tag="VWX48_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU9171283.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            50411..51271
                     /gene="tehB"
                     /locus_tag="VWX48_000617"
     CDS             50411..51271
                     /gene="tehB"
                     /locus_tag="VWX48_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU9171284.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEVMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            51344..52297
                     /gene="coiA"
                     /locus_tag="VWX48_000618"
     CDS             51344..52297
                     /gene="coiA"
                     /locus_tag="VWX48_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU9171285.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            52316..54118
                     /gene="pepF"
                     /locus_tag="VWX48_000619"
     CDS             52316..54118
                     /gene="pepF"
                     /locus_tag="VWX48_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9171286.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            54120..54833
                     /locus_tag="VWX48_000620"
     CDS             54120..54833
                     /locus_tag="VWX48_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU9171287.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            54900..55841
                     /gene="prsA"
                     /locus_tag="VWX48_000621"
     CDS             54900..55841
                     /gene="prsA"
                     /locus_tag="VWX48_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU9171288.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(55960..>56300)
                     /locus_tag="VWX48_000622"
     CDS             complement(55960..>56300)
                     /locus_tag="VWX48_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU9171289.1"
                     /translation="LEQAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEQTFKSLNQLEQAIIDYIDYYNNKRIKIKLKGLS
                     SVQYRTKSFG"
BASE COUNT        16770 a        10410 c        12840 g        16280 t
ORIGIN      
        1 gcttgatttc ttgaccgagc gcttgcgatt gttttcataa gactgttgag catagtcggc
       61 agaataaacc tctttgaagc gcccttttcc aagacattgt cggactgtcc cacgcttgat
      121 ttcagtgtgg atagtttgag gaacttttcc aagcagagag gcaatttttc tatttgattt
      181 cccttctttt ttccatcttt cgattaagcg acggctatcg attgtcaaat gtttggcttt
      241 tgtagtataa ttgtcttgca tctctgtgcc tttcttgtgt ttgtggttga acaacaagta
      301 taacacagag gtgttttctt atgcctacaa gagctatcag ctagttgaac catctaattt
      361 ttaggagggc tgggtggcta acttcattat agaactttca tttacgaaca tatagtaaaa
      421 tgaaacaaga acagaacaaa tcgatcagga cagtaaaatc tatttctaat aatgttttag
      481 aagcagaagt gtactattct agtttcaatc tattatattt ttgtttttta tcaaaaaata
      541 ctttacaagt tcttaaaaac atgatatagt aataaagctt agaaaatgag atgatgtttt
      601 ctagcaaata taaacccgag taaaaaatgc ctacggacag gcagggttga atgccgaagc
      661 gtggttgaaa agccacatta ttgatagggt taaaagccta cttttataag ttgatgttag
      721 gacacttgtc ctaattcata aatttttagt gtggtgaaag cacacgtcat cttgtgaaac
      781 gatcaataaa gtacgtaata tttgctacta gagagttagg aaacatcggg aacagacata
      841 ctcaacagaa accaaaataa acacgtcaga agattgcaga gcaggtgaaa acctgctctt
      901 ttttcatgag tcaaccttta gttccttagt tttcataagg tcctaaaaat attgaaagga
      961 gtatgttttg aaagagttag atcaaaacca agccccaatt tatgaggcct tggtgaagtt
     1021 acgcaagaaa aggattgttc cctttgatgt tccaggtcac aagcgtggac ggggaaatcc
     1081 agaacttgtc gaactcttag gagaaaaatg tgtaggcatt gatgtcaatt cgatgaaacc
     1141 cttggataat ttaggccatc ctatttcgat tattcgtgat gcagaggagc tggctgcaga
     1201 tgcttttgga gctagccatg cctttctaat gattggtgga acaacttcat cggtgcagac
     1261 tatgattctg gcaacctgca aggcaggaga taagattatt ctgccacgaa atgtccataa
     1321 atctgctatc aatgcgttgg ttctatgtgg tgccattccc atctatatcg agatgagtgt
     1381 agatcctaag attggtatcg ctttaggtct tgaaaatgac cgagtagcac aggccataaa
     1441 ggaccatcca gatgctaagg ctatcctaat caacaatcct acttactacg gcatctgttc
     1501 agacctaaag gggttgacag aaatggctca tgaagctggc atgatggttt tagtagatga
     1561 agcccatgga gcgcatttgc atttcactgg taaacttcca atttctgcta tggatgcagg
     1621 agctgatatg gcagcagttt ccatgcataa gtctggtggg agtttgacac aaagttcgct
     1681 tcttttaatc ggggagcaga tgaatcccga atacgttcgt cagattataa acctgaccca
     1741 gtctacatct gcctcttact tattgatggc tagtttggat atttcacgtc gcaacttggc
     1801 ccttcgtggt aaagagtcgt ttgaggaagt cattgagcta tccgagtacg ctcgtcatga
     1861 aatcaatgcc attggcggtt actatgctta ctcaaaagag ttaatagatg gtgtgtcggt
     1921 ctgtgatttt gatgtaacca agttgtcagt ttacactcag ggaataggct taacaggtat
     1981 cgaggtttat gacctcttgc gagacgaata cgacattcag atcgagtttg gtgatatcgg
     2041 caatatcttg gcctatattt ccatcggcga ccgcatccaa gacatcgagc gcttggttgg
     2101 tgctctggct gatattaaga gactctattc acgagatggg aaggacttaa tagctggaga
     2161 atatattcag cccgagttgg tgctgtctcc acaagaagcc ttctattcag agagaaaaag
     2221 tttgacctta gatgagtctg ttggacaggt ctgtggagaa tttgtcatgt gctatcctcc
     2281 agggattcct atcttggctc ctggtgaacg cattacacga gaaattgtag actatatcca
     2341 attcgccaag gaacgtggtt gctccctcca agggacggaa gatccagagg tcaatcatat
     2401 caacgttatt aagagaaaga caaactataa gaaaagtcaa tagttttatc taaactattt
     2461 cttatttcaa tttgatgatt tggcgatgat tttagagcac ggcaaaaagc ccttgaatta
     2521 gaagcggtca atcgcttaat ttctatcagc ttatcaaatc ctgcctcaat ccttttctga
     2581 ggattagggt agcgtgtcaa gagttggtag gtatattctg aatgctttcc aacgatttta
     2641 tccaactcag gaaagatgat atcaagacaa cgagtgtatt gtactttcca atcagactgt
     2701 ttttcttgag acgatgaata tgtctagcca gtatttttag ttctacttgc cgattatcgt
     2761 gttgaaattg ttcacgattg gggtcagaaa gaagtttaag agcgatgcca tgagcgtctt
     2821 tcttatccgt tttagtcttg cgaagtgata atgatttggc aaattccttg atgagcaaag
     2881 gattgcaggt gtaaacttta tatccttgtt catgcaggaa gttcagtaga ttaaaggcat
     2941 aatgtccggt attttcaaga gcgatgagac agtcttggtt gagctgtcga agagacagat
     3001 ctaagagttc aaaaccagct ttattatttg aaaaagtgag tggtttaaga acagtttttc
     3061 ctggaacatt caaggctgta acatcgtgtt tatttttagc gacatcaatg cccacataaa
     3121 gcatgggagt acctccagat gtagtatttc aagtctactt ggttatccac gaattttttg
     3181 ccttgttacc ttagacgaga taaaacgtct atgcgttatc aaactcatta ccaattgaaa
     3241 caaaaaactg tggttagagc ctttcggaaa tcgtcaagcg attggaggga ataaactaat
     3301 ccacagtggc ttattccaag tataccactt gggctttggc agtagctaac tgcgctaaat
     3361 ataatataag gagaaataga tggatttatg gttttctgaa gttcatactc cagatgtcaa
     3421 attgtctctg agaacagcca agcaacttta cgctggaaaa agtgaatggc aggatatcga
     3481 agtcttggat acgccagctt ttgggaaaat actgatttta aatggccatg tcttgttctc
     3541 agatgcggat gatttcgtct acaatgaaat gaccgttcac gttcccatgg ctgtccaccc
     3601 aaatccaaag aaagtattgg ttattggggg tggtgacggc ggtgttgccc aagtattaac
     3661 actctatcct gaactggaac aaatcgatat cgtggaaccg gatgagatgt tggtcgaggt
     3721 ctgtcgtgag tatttcccag actttgctgc agggctagat gatcctcgtg ttaccattta
     3781 ctaccaaaat gggctacgct ttttgcgaaa ctgcgaagat gattacgata ttatcatcaa
     3841 cgatgcgaca gatccatttg gccatacgga aggactcttt accaaggaat tctacggcaa
     3901 tagttatcga gctctgaagg aagacggcat catgatttac cagcatggga gtcccttctt
     3961 tgacgaggat gagtcggcct gccgaagcat gcaccgcaag gtcaatcaat cctttccaat
     4021 cagtcgggtt tatcaggccc atattccaac tagcccagct ggctattggt tgtttggatt
     4081 tgcatcgaaa aaataccacc ctgtcaaaga ttttgacaag gaaggttgga aaaaacgcca
     4141 gcttttcaca gaatactaca ctgcaaactt acacgtggga tcctttatgt tgcccaagta
     4201 tgttgaggac attttagaag aagaggaagg aaaaaaatga gtcgtttact agttattggt
     4261 tgtgggggcg ttgcccaagt tgctatttca aagatttgtc aagatagcga aacatttaca
     4321 gagattatga ttgctagccg taccaagtca aaatgcgatg acttgaaagc gaagctagaa
     4381 ggcaaaacaa gtactaaaat tgaaactgca gcacttgatg ctgacaaggt tgaagaagtg
     4441 attgccctga ttgaaagcta caaaccagaa gctgttttga atgtagctct gccttatcaa
     4501 gatttaacca ttatggatgc ttgtttggca acaggtgttc actatatcga tacagccaac
     4561 tacgaagcag aagacacaga agaccctgag tggcgtgcta tctacgaaaa acgttgtaag
     4621 gaacttggtt ttacagccta ctttgactac tcatggcagt gggcttatca agagaaattc
     4681 aaagaagcag gcttgactgc tcttcttggt tctggctttg acccaggtgt aactagtgtc
     4741 ttttcagctt atgccctcaa acactatttt gatgaaatcc attatatcga cattttagac
     4801 tgtaatggcg gtgaccacgg ttatccattt gcaaccaact ttaatccaga aattaatctc
     4861 cgtgaggttt ctgcgccagg ttcttactgg gaagatggga aatgggtcga agtcgaagct
     4921 atgtctatca agcgtgagta tgatttccct caagttggac aaaaagatat gtatctcctt
     4981 caccatgaag aaatcgaatc attggccaag aacattccag gtgtcaaacg cattcgtttc
     5041 tttatgactt ttggtcaatc ttacttgacg cacatgaaat gtcttgaaaa tgttggactc
     5101 cttcgtacgg ataccattaa ctttaacggc caagaaattg ttccaattca atttttgaaa
     5161 gccttgcttc cagatcctgc tagccttggc ccacgtactg taggtaaaac caatattgga
     5221 tgtatcttta caggtgtcaa agatggcgtt gaaaagacta tctacatcta caatgtttgc
     5281 gaccatcaag agtgctatgc agaagtcggg tcacaagcaa tttcatacac gacaggcgtt
     5341 ccagccatga ttgggacaaa attagtcatg aacggaactt ggaaacaagc tggagtgtat
     5401 aaccttgagg agttagatcc agatccattc atggaagctt tgaatgagta tggtttgcca
     5461 tgggttgtgg ttgaaaatcc acaaatggtg gactaatgaa gttagaacaa gtaccaacac
     5521 cagcctatgt tattgacttg gccaagttag aagctaattg ccgcattcta caatatgtac
     5581 aagaagaggt cggttgcaag gtcttgcttg cccagaaggc atattccctc tacaaaactt
     5641 atcccttgat tagccagtat ctatcaggta cgacagctag tggactctat gaggccaaat
     5701 tggcaaggga agaatttcct ggtgaagtcc atgtatttgc gcctgctttc aaggatgcag
     5761 acttggagga attgcttggg ataacagacc atatcgtctt taactcagag agacagttgc
     5821 gtaagcatgg ggctcgttgt cgagaggctg gtgtcagtgt tggtttgcgc ctcaaccctc
     5881 agtgttcaac tcaaggagat cacgcgctct atgacccttg tgcaccaggt tctcgctttg
     5941 gagttactat agacaagatt ccgagtgatt tgctagattt ggttgacgga cttcattttc
     6001 ataccctttg cgagcaggga gcagatgatt tacaaacaac tttgaaagca gtagaagaac
     6061 agtttggtcc ctacttacat gaggtaaaat ggctcaatat gggtggtggt catcatatta
     6121 caagagaagg ttacgatgtg gatttgctga tttcagaaat caagcgtatc cgaaaaactt
     6181 acaatcttga aatctatatc gagcctggtg aagccattgc gcttaatgcg ggttatttag
     6241 caactgaggt attagatatt gtagaaaacg gtatggaaat cttggtttta gacgcctctg
     6301 cgacctgcca tatgcctgat gtacttgaga tgccctatcg tccacctttg agaaatggct
     6361 ttgaggcaca ggaaaaagcc catacctaca gactttcttc taatacctgt ctgacgggcg
     6421 atgtgattgg tgattatagt tttgaaaatc cagtccaaat cggagacaga ctttattttc
     6481 aagacatggc catttattct tttgtcaaaa ataatacctt taatggtatt ggattgccaa
     6541 gtctctatct catggacgaa cagggagact gtagcttact caaagctttt ggctatcaag
     6601 actttaaagg gagattatca tgatggacag tccaaaaaaa ttaggctatc acatgccagc
     6661 agagtacgaa ccccatcatg gtaccctcat gatatggccg actcgaccag gatcatggcc
     6721 ttttcaagga aaggatgcta aaagagcatt tactcagatc atcgagacta tagcagaagg
     6781 ggaaagagtc tatcttttgg tggagcaggc ctatctatct gaagcccaat cctatcttgg
     6841 ggacaaggtt gtttatttag acattcccac caatgatgcc tgggcgcgtg atactggccc
     6901 aaccattctc gtcaatgata aaggtaagaa attagccgtg gattgggcct tcaatgcttg
     6961 gggaggcacc tatgatggtc tttatcaaga ttatgaagag gatgaccaag tagccagtcg
     7021 ttttgctgag gccttggaaa ggcctgtcta tgatgctaaa ccttttgtac tggaaggagg
     7081 cgcaatccat agcgatggtc aaggaactat tctcgtaact gaaagttgct tgcttagtcc
     7141 tggtcgcaat cctaacttga ctaaagagga gattgaaaac acattattag aaagtcttgg
     7201 tgctgaaaaa gttatttggc ttccttatgg tatttatcag gatgaaacca atgaacacgt
     7261 cgataatgtt gctgcctttg ttggtcctgc tgaggttgtt ttggcttgga cagatgacga
     7321 aaatgatccc cagtatgcca tgtcaaaagc agatctcgaa ctcttagaac aggaaacaga
     7381 tgcaaaaggt tgtcacttca ccattcataa attgcctatc cctgcagttc gacaagttgt
     7441 gacagaagaa gatttgccag gctacatcta tgaagaagga gaagaagagc gatacgcagg
     7501 tgaacgacta gcagcttcct acgtaaactt ttatatcgcc aacaaggctg tcttggttcc
     7561 acagtttgag gatgtaaacg accaagtggc cttagatatc ctcagcaagt gtttcccaga
     7621 ccgtaaagtt gtcggaatac cagccagaga tattctctta ggtggtggca atatccactg
     7681 tatcacccaa caaattccag aataggagaa aaagatgaga aatgtaagag ttgcaaccat
     7741 tcagatgcaa tgcgctaagg atgtggcaac aaatatccaa accgcagagc gtttagtacg
     7801 tcaggctgct gagcaaggag cccaaattat tctcttgccc gagttgtttg aacatcccta
     7861 tttctgtcag gaacgtcagt atgactacta ccagtatgcc caatctgtag cggaaaatac
     7921 tgccattcag cattttaagg tgattgctaa ggaactacaa gttgttttac caatcagttt
     7981 ctatgaaaaa gatggtaatg tcttgtataa ctctattgcc gtcattgatg cagatgggga
     8041 agtgctgggc gtttatcgaa agacccacat accagatgac cattattatc aagaaaaatt
     8101 ctatttcacg cctggtaaca ctggtttcaa ggtctggaat actcgctatg ctaagattgg
     8161 tatcggtatc tgttgggatc aatggttccc tgaaacagcc cgctgtcttg cattgaatgg
     8221 tgctgaattg ctcttttatc ctacagctat cggttcagag ccaattttgg atacagatag
     8281 ttgtggtcac tggcaacgta ctatgcaagg gcacgcagca gcgaatattg ttccagtcat
     8341 cgcagccaat cgttatggtt tagaggaggt tactcctagt gaggaaaatg gcggacagag
     8401 ttccagtctt gacttctacg gttcctcctt tatgacggat gaaacaggag ctattctaga
     8461 acgagctgaa agacaagaag aagctgttct gttagctact tatgacctag acaagggagc
     8521 aagtgaacgt ctaaactggg gcttgtttcg agatagaaga ccagaaatgt atagacaaat
     8581 tacagattag tgtgggagaa atgagagatt cattctgcta gactaacttc ttattagcaa
     8641 ctataagata ctatggcatc tagtaaatcg atttttatga ttcgctattc ttgtctattg
     8701 attagtccgt attttaaata ttagcaaaaa agcaaatagc agtaacttct gtctatttgc
     8761 ttttcttttt ttatagaata tatttctcaa tagcacgcgc aacgccgtct tcttcgttgc
     8821 ttgaggtaac ggcatccgca agagatttga cataatcgct ggcatttccc attgcaatcc
     8881 caagccctgc aaactggagc atttcgatat cgttattagc atcgcccatg gccataatct
     8941 ctgaggaatc aatcttcaaa atctcagcaa gtcgtgaaag agcagtagcc tttgtcgttc
     9001 caagtggcat tgcttcataa atgacaggct gcgaacgaac tccactgaat cgttggcaaa
     9061 gctcttcagc aaaacgctgc tcaaaatcgt ctgtttgttc ttttgttcct aaaaacatac
     9121 cttggaacat ccggaacttt ccactagtcg cttcttcaag agaaatttca gtcaggtctg
     9181 aaaatactag tttagcatca ttttcaataa cttgattggg cttgccaccg agaacaaaat
     9241 aatgtgactc gtcaaaaagt gtcaactgaa catcactctt ttcagcaagg tcatagaggt
     9301 attcgatgtc agctggactc agttcttgcc agtcaaccaa gccccagtcg ctagtctggt
     9361 gagttgaaca accgttgtta acaatcacat attcgttctg gaggtcgagt cccagttttt
     9421 tgtagtaggg gaggacaccg aaaagggggc gacccgtaca gagaaccagt ttgacacctt
     9481 tttcaatggc ttggtgaata gcagcgatgt gagcctgtgg gatttccttg gcttcattga
     9541 ggagggttcc atccatatcc aaggctagta gtttaatcat aggtcttcct tctttatctt
     9601 ttgctattat tatagcatat tttggagaag aaattgatag aaagcttgag actaattgat
     9661 tttatagttt aagatgtttt gatgacaatt catgatttga agaggatatt tggcaaagat
     9721 atgctatact atgtttgtca atgttgcaac tagacaaatt aaaaaaccaa cttaatataa
     9781 tagttttttt tgtaagtagg tatgagtagc agattactca actaatctaa acaataacgg
     9841 aggaaatata tcatgatttt aatgacaaaa aatataaatc taacaaatga agaattagag
     9901 ctgatacaag gtggagcaga tccctatggt aaagaaccta atggttatta tccttggcaa
     9961 atggaaccag tattaactat gccggttcat ggattttgtc ccagaggaac cgatgattta
    10021 ggatatattg gaggaggtaa tcatctttgc aaaggaagtg ctgcgagatt ttaagtaaaa
    10081 tttattagga atatgaagaa acaaggggag aaaacagagg atttaatatg aaaaaacggg
    10141 ctattcaaat tttactagca ttgtccttaa ttttttacaa atcaacttgg ttttggagag
    10201 ttttcaatca cctcgcaaag ccctatctac cagcaagtcg tgaatttttt cagattctgc
    10261 ttttgatgga gagcggagtt cttttcttag cggtcatcta tctactggtt tttgcaggaa
    10321 agaaaatttt tcatttcaag tggcagctga ggtacttcat ctacctttta ctgggctaca
    10381 tcatttcata tatgtctgac ttcctctttt cgtatttcat atccccgcct tcaaatcaaa
    10441 tttctttgaa tgaaacggta gaaatgatgg ggagacagga gttcccttat ttcttgctca
    10501 tcgtttgctt catcgcccct attgctgagg aattgattta tcgaggtgtg cttatgacaa
    10561 cctttttcaa aaactcacct tggtacggag atgttttgct ttctgctatt attttcggtt
    10621 atattcatat caattttgct ttaactcctc ttgctttttt catttatgct agtggaggtc
    10681 ttattttagc tctattgtat cgcatgacta aaaatctcta ctatccaata ctagttcata
    10741 ttctcattaa tatcactgcc ttctgggacg tgtggttgct cctattttca ggaagttagc
    10801 ttactaaaat aatgtcggaa ctttccagca ttttcttttt tcacaaatag tcaacgtttt
    10861 tctttccgat actgaagtgg tgtgtagcca cttatttttt tgaattgatt ttgaaaataa
    10921 ggttggcttg agaaaggcag atagtgaaga agaataggat gttctttttt cctttttgga
    10981 aaacttctaa aatatggtat aatgaaaaga taaagaagtt aggggtagaa gatgaacatt
    11041 caacaattac gctatgttgt ggccattgcc aatagtggta ctttccgtga agctgctgaa
    11101 aagatgtatg ttagtcagcc gagtctgtct atttctgttc gtgatttgga aaaagagttg
    11161 ggttttaaga ttttccgtcg gaccagctca gggactttct tgacccgtcg tgggatggaa
    11221 ttctatgaaa aatcgcaaga attggttaaa ggatttgata tttttcaaaa tcagtatgcc
    11281 aatcctgaag aagaaaaaga tgaattttct gttgctagcc agcactatga cttcttgcca
    11341 ccaactatta cggccttttc agagcgctat cctgactata agaacttccg tatttttgaa
    11401 tcaactactg ttcaaatatt agatgaagtg gcgcaagggc atagtgagat tgggattatc
    11461 tacctcaaca atcaaaataa aaaggggatt atgcaacggg ttgaaaaatt aggtctggag
    11521 gtcatcgaat tgattccttt ccatacccat atttatctcc gtgagggtca tcctttagcc
    11581 cagaaagagg aattagtcat ggaggattta gcggatttac caacggttcg tttcactcaa
    11641 gagaaagacg agtaccttta ttattcagag aactttgtcg ataccagcgc tagctcacag
    11701 atgtttaatg tgacagaccg tgccaccttg aatggtattt tggagcggac ggacgcctat
    11761 gcgacaggtt ctggattttt agatagtgac agtgttaatg gtattacagt tattcgtctc
    11821 aaggataacc tagataaccg catggtctat gttaaacgtg aagaagtgga gcttagtcaa
    11881 gctgggactc tcttcgtaga agtcatgcaa gaatattttg atcaaaagag gaaatcatga
    11941 aaaaaagagc aatagtggca gtcattgtac tgcttttaat tgggctggat cagttggtca
    12001 aatcctatat cgtccagcag attccactgg gtgaagtgcg ctcctggatt cccaatttcg
    12061 ttagcttgac ctacctgcaa aatcgaggtg cagccttttc tatcttacaa gatcagcagc
    12121 tgttattcgc tgtcattact ctggttgtcg tgataggtgc catttggtat ttacataaac
    12181 acatggagga ctcattctgg atggtcttgg gtttgactct aataatcgcg ggtggtcttg
    12241 gaaactttat tgacagggtc agtcagggct ttgttgtgga tatgttccac cttgacttta
    12301 tcaactttgc aattttcaat gtggcagata gctatctgac ggttggagtg attattttat
    12361 tgattgcaat gctaaaagag gaaataaatg gaaattaaaa ttgaaactgg tggtctgcgt
    12421 ttggataagg ctttgtcaga tttgtcagaa ttatcacgta gtcttgcgaa tgaacaaatt
    12481 aaatcaggcc aggtcttggt caatggtcaa gtcaagaaag ctaaatacac agtccaagag
    12541 ggtgatgtcg tcacttacca tgtgccagaa ccagaggtat tagagtatgt ggctgaggat
    12601 cttccgctag aaatagtcta ccaagatgag gatgtggctg tcgttaacaa acctcaggga
    12661 atggttgtgc acccgagtgc tggtcatacc agtggaaccc tagtaaatgc cctcatgtat
    12721 catattaagg acttgtcggg tatcaatggg gttctgcgtc cagggattgt tcaccgtatt
    12781 gataaggata cgtcaggtct tctcatgatt gctaaaaacg atgatgcgca tctagcactt
    12841 gcccaagaac tcaaggataa aaagtctctc cgcaaatatt gggcgattgt tcatggaaat
    12901 ctgcctaatg atcgtggtgt aattgaagcg ccgattggcc ggagtgaaaa agaccgtaag
    12961 aaacaggctg taactgctaa agggaagcct gcagtgacgc gttttcacgt cttggaacgc
    13021 tttggcgatt atagcttagt agagttgcaa ctggagacag ggcgcactca tcaaatccgt
    13081 gtccacatgg cttatatcgg ccattcagtc gctggtgatg aggtctatgg tcctcgcaag
    13141 actttgaaag gacatggaca atttcttcat gccaagactt taggttttac tcatccgaga
    13201 acaggtaaga ccttggaatt taaagcagat atcccagaga tttttaagga aaccttggag
    13261 agattgagaa agtaagaatg aaaaagaaat taactagttt agcacttgta ggcgcttttt
    13321 taggtttgtc atggtatggg aatgttcagg ctcaagaaag ttcaggaaat aaaatccact
    13381 ttatcaatgt tcaagaaggt ggcagtgatg cgattattct tgaaagcaat ggacattttg
    13441 ccatggtgga tacaggagaa gattatgatt tcccagatgg aagtgattct cgctatccat
    13501 ggagagaagg aattgaaacg tcttataagc atgttctaac agaccgtgtc tttcgtcgtt
    13561 tgaaggaatt gggtgtccaa aaacttgatt ttattttggt gacccatacc cacagtgatc
    13621 atattggaaa tgttgatgaa ttactgtcta cctatccagt tgaccgagtc tatcttaaaa
    13681 aatatagtga taatcgtatt actaattctg aacgtctatg ggataatctg tacggttatg
    13741 ataaggtttt acagactgct tcagaaaaag gtgtttcagt tattcaaaat atcacacaag
    13801 gggatgctca ttttcagttt ggggacatgg atattgagct ctataactat gaaaatgaaa
    13861 ccgattcatc gggtgaatta aagaaaattt gggatgataa ttccaattcc ttgattagtg
    13921 tggtaaaagt caatggcaag aaaatttacc ttgggggcga cttagataat gttcatggag
    13981 cagaagacaa gtatggtcct ctcattggaa aagttgattt gatgaagttt aatcatcacc
    14041 atgataccaa caaatcaaat accaaggatt tcattaaaaa tttgagtccg agtttgattg
    14101 ttcaaacttc ggatagtcta ccttggaaaa atggtgttga tagtgagtat gttaattggc
    14161 tcaaagaacg aggaattgag agaatcaacg cagccagcaa agactatgat gcgacagttt
    14221 ttgatattcg acaagacggt ttagtaaaca tttcaacttc ctacaagccg attccaagtt
    14281 ttcaagctgg ttggcataag agttcatatg gaaactggtg gtatcaagcg cctgattcta
    14341 caggagaata tgctgtcggt tggaatgaaa ttaagggtga atggtattac tttaaccaaa
    14401 cgggtatctt attacagaat caatggaaaa aatggaacaa tcgttggttc tatttgacag
    14461 actctggtgt tgctgctaaa aattggaaga aaatcgctgg aatctggtat tattttaaca
    14521 aagaaaatca gatggaaatt ggttgggttc aagataaaga gcagtggtat tatttggatg
    14581 ttgatggttc tatgaagaca ggatggcttc aatatatggg gcaatggtat tactttgctc
    14641 catcagggga aatgaaaatg ggctgggtaa aagataaaga aacctggtac tatatggatt
    14701 ctactggtgt catgaagaca ggtgagatag aagttgctgg tcaacattat tatctggaag
    14761 attcaggagc tatgaagcaa ggctggcata aaaaggcaaa tgattggtat ttctacaaga
    14821 cagacggttc acgagctgtg ggttggatca aggacaagga taaatggtac ttcttgaaag
    14881 aaaatggtca attacttgtg aacggtaaga caccagaagg ttatactgtg gattcaagtg
    14941 gtgcctggtt agtggatgtt tcgatcgaga aatctgctac aattaaaact acaagtcatt
    15001 cagaaataaa agaatccaaa gaagtagtga aaaaggatct tgaaaataaa gaaacgagtc
    15061 aacatgaaag tgttacaaat ttttcaacta gtcaagattt gacatcctca acttcacaaa
    15121 gctctgaaac gagtgtaaac aaatcggaat cagaacagta gtagaaaaga aggttttagg
    15181 gccttctttt tcctatcaac tcttttctat ttcctgttat tcatgttata atggataaat
    15241 atgaataatc ggagtgagac tatgaaatac aaacggattg tctttaaggt gggtacttct
    15301 tctctgacaa atgaggatgg aagtttatca cgtagtaagg taaaggatat tacccagcag
    15361 ttggctatgc tgcacgaggc tggtcatgag ttgattttgg tgtcttcagg tgccattgcg
    15421 gctggttttg gagccttagg atttaaaaag cgtccgacta aaattgctga taaacaggct
    15481 tcagcagcgg tagggcaggg acttttgttg gaagaatata cgaccaatct tctcttgcgt
    15541 caaatcgttt ctgcacaaat cttgctgacc caagatgact ttgtggataa gcgtcgttat
    15601 aaaaatgccc atcaggcttt gtcggttttg ctcaaccgtg gggcaattcc tatcatcaat
    15661 gagaatgata gtgtcgttat tgatgagctc aaggttgggg acaatgacac tctaagtgct
    15721 caagtagcgg cgatggtcca agcagacctt ttagttttct tgacagatgt ggacggtctc
    15781 tatactggaa atcctaattc agatccaaga gccaaacgct tggagagaat cgagaccatc
    15841 aatcgtgaga ttattgatat ggctggtgga gctggttcgt caaacggaac tgggggtatg
    15901 ttaaccaaaa tcaaggctgc aactatcgcg acggaatcag gagttcctgt ttatatctgc
    15961 tcatccttga aatcagattc catgattgag gcggcagagg agaccgagga tggttcttac
    16021 tttgttgctc aagagaaggg gcttcgtacc cagaaacaat ggcttgcctt ctatgctcag
    16081 agtcaaggtt ctatttgggt tgataaaggg gctgcggaag ctctctctca acatggaaag
    16141 agtcttctct tatctggtat cgttgaagca gaaggagcct tttcttacgg tgatatcgtg
    16201 acagtatttg acaaggaaag tggaaaatca cttggaaaag gacgcgtgca atttggagca
    16261 tctgctttgg aggatatatt gcgttctcaa aaagccaagg gtgtcttgat ttaccgtgac
    16321 gactggattt ccattactcc tgaaatccaa ctacttttta cagaatttta gaggtaaact
    16381 atggtgagta gacaagaaca atttgaacag gtacaggctg ttaaaaaatc gattaacaca
    16441 gctagtgaag aagtgaaaaa tcaagccttg ctagccatgg ctgatcactt agtggctgct
    16501 actgaggaaa ttttagcggc taatgccctc gatatggcag cggctaaggg gaaaatctca
    16561 gatgtgatgt tggatcgtct ttatttggat gcagatcgta tagaagcgat ggcaagagga
    16621 attcgtgaag tggttgcctt cccagatcca atcggtgaag ttttagaaac aagtcagctt
    16681 gaaaatggtt tggttatcac aaaaaaacgt gtagctatgg gtgtcatcgg tattatctat
    16741 gaaagccgtc caaatgtgac gtctgatgcg gctgctttga ctcttaagag tggaaatgcg
    16801 gttgttcttc gtagtggtaa ggatgcctat caaacaaccc atgccattgt cacagccttg
    16861 aagaagggct tggagacgac tactattcac ccaaatgtga ttcaactggt ggaagatact
    16921 agccatgaaa gtagttatgc tatgatgaag gccaagggct atctagacct cctcattcct
    16981 cgtggaggag ctggcttgat caatgcagtg gttgagaatg cgattgtacc tgttatcgag
    17041 acagggactg ggattgtcca tgtctatgtg gataaggatg cagacgaaga caaggcgctg
    17101 tctatcatca acaatgctaa aaccagtcgt ccttctgttt gtaatgccat ggaggttctg
    17161 ctggttcatg aagacaaggc agcaagcatc cttcctcgct tggatcaaat gctggttgca
    17221 gagcgtaagg aagctggact ggaaccaatt caattccgct tggatagcaa agcaagccag
    17281 tttgtttcag gtcaagcagc tgagacccaa gactttgaca ccgagttttt agactatgtc
    17341 cttgctgtta aggttgtgag cagtttagaa gaagcggttg cgcacattga atcccacagc
    17401 acccatcatt cggatgctat tgtgacggaa aatgctgaag ctgcagcata ctttacagat
    17461 caagtggact ctgcagcggt gtatgttaat gcctcaactc gtttcacaga tggaggacaa
    17521 tttggtcttg gttgtgaaat ggggatttct actcagaaat tgcacgcgcg tggtccaatg
    17581 ggcttgaaag agttgaccag ctacaagtat gtggttgctg gtgatgggca gataagggag
    17641 taagagatga agattggatt tatcggtttg gggaatatgg gtgctagctt ggcaaaatct
    17701 gtcttgcaga ctaggacgtc agatgagatt ctccttgcca atcgtagtca agctaaggta
    17761 gatgctttca ttgcagactt tggtggtcag gcttccagca atgaagaaat gtttgcagaa
    17821 gcagatgtga tttttctagg agttaagcct gctcagtttt ctgaactgct ttctcaatac
    17881 cagaccatcc ttgaaaaaag agaaagtctt cttttgattt cgatggcagc tggattgacc
    17941 ttagaaaaac tagcaagtct tatcccaagc caacaccgaa ttattcgtat gatgcctaat
    18001 acccctgctt ctatcgggca aggagtgatt agttatgcct tgtctcctaa ttgcagggct
    18061 gaggacagtg agatcttttg tcagctttta gccaaggctg gtctcttggt tgaattagga
    18121 gaaagcttaa tcaatgcagc gacaggtctt gcaggttgtg gaccagcctt tgtctatctc
    18181 tttattgagg ccttggcaga tgcaggtgtt cagacgggat taccacgaga aacagccttg
    18241 aaaatggcag cccaaactgt ggtaggagct gggcaattgg tcctagaaag ccagcaacat
    18301 cctggagttt tgaaagatca agtttgtagt ccaggcggtt cgactattgc tggcgtagca
    18361 agcctagaag cgcatgcttt tcgaggcaca gtcatggagg cagttcatca agcctataaa
    18421 cgaacacaag aactaggtaa ataagaggta gctttgactg cctcttttat ggtggttgat
    18481 actcttcgaa aatcaaattc aaactgcgtc agcttcacct tgccgtactc aagtacagcc
    18541 tgcggctagc ttcctagttt gctctttgat tttcattgag tatgaaatga gaagacaaaa
    18601 agattgtcac aaacccctat ttttttgata gaatagaagt agtaaaaaag aaatgagtta
    18661 gacatgtcaa aaggattttt agtctctctt gagggaccag agggagcagg caagaccagt
    18721 gttttagagg ctctgctacc aattttagag gaaaaaggag tagaggtgtt gacgacccgt
    18781 gaacctggcg gagtcttgat tggggagaag attcgggaag tgattttgga tccaagtcat
    18841 actcagatgg atgctaaaac agagctactt ctctatattg ccagtcgcag acagcatttg
    18901 gtggaaaaag ttcttccagc ccttgaagct ggcaagttgg tcatcatgga tcgttttatc
    18961 gatagttctg ttgcctatca gggatttggt cgtggcttag atattgaagc cattgactgg
    19021 ctcaatcagt ttgcgacaga tggcctcaaa cccgatttga cactctattt tgacatcgag
    19081 gtggaagaag gactggctcg tattgctgct aatagtgacc gcgaggttaa tcgtttggat
    19141 ttggaagggt tggacttgca taaaaaagtt cgtcaaggct acctttctct tctggataaa
    19201 gagggaaatc gcattgtcaa gattgatgct agtctccctt tggagcaagt tgtggaaact
    19261 accaaggctg tcttgtttga cggaatgggc ttggccaaat gaaacaagat caactaaagg
    19321 cttggcaacc agctcagttt gaccgttttg tccgtatctt agaacaagac cagctcaatc
    19381 acgcctatct cttttcaggt ttctttggaa gcttggaaat agcgcaattt ttagctaaga
    19441 gcctcttttg tacggataaa gttggcgtct taccatgtga gaaatgccga agttgcaagc
    19501 tgattgaaca ggaagagttt ccagatgtca ccttgattaa gccagtcaat caggtcatca
    19561 agacagaacg cattcgggaa ttggtgggac agttttctca agcagggatt gaaagccagc
    19621 aacaggtctt tatcatcgag caagcggata aaatgcatcc caacgcagcc aattctctgc
    19681 tcaaggtcat cgaagaaccc cagagtgaag tttatatttt cttcttgact agcgatgagg
    19741 aaaagatgtt accgacaatc cgaagtcgga cccagatctt ccactttaaa aagcaagaag
    19801 aaaaacttat cttactctta gaacaaatgg gacttgttaa gaaaaaagcg actcttttag
    19861 ctaagtttag tcaatcgcga gctgaagcag aaaagttggc taatcaggca agtttttgga
    19921 ccttggtcga tgaaagtgaa cgcctgctga cttggttagt agctaagaaa aaagaaagtt
    19981 atctacaggt tgccaaatta gccaacttgg cagatgataa ggaaaaacag gatcaggttt
    20041 tacggattct tgaagttctc tgtgggcagg acctcttgca ggtaagagta agagtgattc
    20101 tacaagattt actagaagct agaaaaatgt ggcaagttaa tgtcagcttt caaaatgcca
    20161 tggaatatct ggtcttgaaa gaaatataaa ctcaaaaatg aatgataaag aaaggaaagg
    20221 gctgttttat ggacaaaaaa gaattatttg acgcgctgga tgatttttcc caacaattat
    20281 tggtaacctt agccgatgtg gaagccatca agaaaaatct caagagcttg gtagaagaaa
    20341 atacagctct tcgcttggaa aatagtaagt tgcgagaacg cttgggtgag gtggaagcag
    20401 acgctcccgt caaggccaag catgttcgcg aaagtgtccg tcgtatttac cgtgatggat
    20461 ttcacgtatg taatgatttt tatggacaac gtcgagagca ggacgaagaa tgtatgttct
    20521 gtgatgagtt gttatacagg gagtaagcat gcaaattcaa aaaagtttta aggggcagtc
    20581 tccctatggc aagctgtatc tagtggcaac gccgattggc aatctagatg atatgacttt
    20641 tcgtgctatc cagaccttga aagaagtgga ctggattgct gctgaggata cgcgcaatac
    20701 agggcttttg ctcaagcatt ttgacatttc caccaagcag atcagttttc atgagcacaa
    20761 tgccaaggaa aaaattcctg atttgattgg tttcttgaaa gcagggcaaa gtattgctca
    20821 ggtctctgat gccggtttgc ctagcatttc agaccctggt catgatttag ttaaggcagc
    20881 tattgaggaa gaaattgcag ttgtgactgt tccaggtacc tctgcaggaa tttctgcctt
    20941 gattgccagt ggtttagcgc cacagccaca tatcttttac ggttttttac cgagaaaatc
    21001 aggtcaacag aagcaatttt ttggctctaa aaaagattat cctgaaacac agatttttta
    21061 tgaatcgccc catcgtgtgg cagatacatt ggaaaatatg ctagaagtct acggtgaccg
    21121 ctcggtagtc ttggttagag aattgaccaa aatctatgaa gaataccaaa gaggtacaat
    21181 ttctgaattg ctggaaagca tctctgaaac gtctctcaag ggtgaatgtc ttctgattgt
    21241 tgaaggtgcc agcaaaggtg tggaggaaaa ggatgaggaa gacttgttct tagaaatcca
    21301 agcccgtatc cagcaaggca tgaagaaaaa tcaagctatt aaggaagtcg ctaagattta
    21361 ccagtggaat aaaagtcagc tctacgctgc ctaccacgac tgggaagaaa atcaagaaaa
    21421 tgactaaaca gggaagtttg ccttcttccc tttttttgtt atactagtag aagaaaaaat
    21481 tagaaagatt tgtgggagtg aaaaagtcct gtggactttt tcagcctgag ccaagaaact
    21541 cgaaagctcg taagtctgat tggctttttc aatgtgaatc ttaacttcac actcccaaag
    21601 aggtattagt gtcgtgtctc aatcttatat caatgttatc ggtgctggtt tggcaggttc
    21661 tgaagcagct taccaaatcg cagagcgtgg tattccagtt aaactatatg aaatgcgtgg
    21721 tgtcaagtct acaccccagc ataaaacaga caattttgct gagttggttt gttccaattc
    21781 tttgcgtggg gatgctttga caaatgcagt tggtcttctc aaggaagaaa tgcgtcgctt
    21841 gggttctgtt atcttggaat ctgctgaggc tacacgtgtt cctgccggtg gagcccttgc
    21901 ggtggatcgt gatggtttct ctcaaatggt gaccgaaaaa gtggtcaacc accccttgat
    21961 tgaagtggtg cgtgatgaaa ttacagaatt gccaacagat gttattacag ttgtggcgac
    22021 tggtcccttg actagcgatg ccctggctga aaagattcat gcccttaata atggcgatgg
    22081 cttctatttc tacgatgcag cagcgcctat tatcgatgtc aacactatcg atatgagtaa
    22141 ggtctatctc aaatctcgtt atgataaggg agaagcagcc tatctcaatg ctccaatgac
    22201 caagcaagag tttatggatt tccatgaagc cttggtcaat gcggaagaag caccgctcaa
    22261 ttcttttgaa aaagaaaagt actttgaagg atgtatgcca atcgaagtta tggccaaacg
    22321 tggcattaaa actatgcttt atggccctat gaagccagtc ggtcttgagt atccggacga
    22381 ctacacagga cctcgtgatg gagaatttaa aacaccttat gcggttgtgc aacttcgtca
    22441 ggataatgca gctggtagcc tctacaatat cgttggtttc cagacccacc tcaaatgggg
    22501 agaacaaaag cgtgtcttcc aaatgattcc gggtcttgaa aatgcggagt ttgtccgtta
    22561 tggtgtcatg catcgcaatt cttacatgga ttcaccaaat cttcttgagc agacttaccg
    22621 ttccaagaaa caaccaaatc tcttctttgc tggtcagatg acgggggtgg aaggctatgt
    22681 tgagtcggcg gcttcgggct tagttgcggg aattaacgca gctcgtctct tcaaggaaga
    22741 aagcgaggtt attttccccg agacgacagc gattggaagc ttagctcatt acattaccca
    22801 tgccgacagc aaacatttcc aaccaatgaa tgtcaatttt gggatcatca aggagttgga
    22861 aggcgagcgt atccgtgata agaaggctcg ttatgaaaaa attgcagagc gtgcccttgc
    22921 cgacttagaa gaatttttga ctgtctaatt tttttgaaag aattgctcat gatactataa
    22981 aaatcttaga aattgtgata aaataggtag gatgaaagaa ggagagtgaa aatggcgaat
    23041 cccaagtata aacgtatttt aatcaagtta tcaggtgaag cccttgccgg tgaacgtggc
    23101 gtagggattg atatccaaac agttcaaaca atcgcaaaag agattcaaga agttcatagc
    23161 ttaggtatcg aaattgccct tgttattggt ggaggaaatc tctggcgtgg agaacctgca
    23221 gcagaagcag gtatggaccg tgttcaggca gattacactg gaatgcttgg gactgttatg
    23281 aatgctcttg tgatggcaga ttcattgcaa caagttgggg ttgatacgcg tgtacaaaca
    23341 gctattgcta tgcaacaagt ggcagagcct tatgtccgtg gacgtgccct tcgtcacctt
    23401 gaaaaaggcc gtatcgttat ctttggtgct ggaattggtt caccatactt ctcgacagat
    23461 acaacagcgg cccttcgcgc agctgaaatc gaagcagatg ccatcctcat ggctaaaaat
    23521 ggcgtcgatg gtgtgtacaa tgccgatcct aagaaggaca agacagccgt taagtttgaa
    23581 gaattgaccc accgtgatgt tatcaacaaa ggtcttcgta tcatggactc aacagcctca
    23641 accctctcaa tggacaacga cattgacttg gttgtcttca acatgaacca atcaggcaac
    23701 atcaaacgtg tcgtatttgg tgaaaatatc ggaacaacag tttcaaataa tatcgaagaa
    23761 aaggaataag aaagaatatg gctaacataa ttattgaaaa agctaaagag agaatgaccc
    23821 agtctcacca atcacttgct cgtgaatttg gtggtatccg tgctggtcgt gccaatgcaa
    23881 gcttgcttga ccgtgtacat gtagaatact atggagtcga aactcctctt aaccaaatcg
    23941 cttcaattac gattccagaa gcgcgtgttt tgttggtaac accatttgac aagtcttcat
    24001 tgaaagacat cgaacgtgcc ttgaacgctt ctgatcttgg tatcacaccg gctaatgacg
    24061 gttctgtgat tcgcttggtt atcccagctc ttacagaaga aactcgtcgt gaccttgcta
    24121 aagaagtgaa gaaggtcggc gaaaatgcta aagtggctgt ccgcaatatc cgtcgcgatg
    24181 ctatggacga agctaagaaa caagaaaaag caaaagaaat cactgaagac gaattgaaga
    24241 ctcttgaaaa agatattcaa aaagtaacag acgatgctgt taaacacatc gacgacatga
    24301 ctgctaacaa agagaaagaa cttttggaag tctaaaaata aacagaaaaa ctcagttggc
    24361 attgctggct gagttttatt cgaaagaagg aaatatgaat acaaatcttg caagttttat
    24421 cgttggactg atcatcgatg aaaatgaccg tttttacttt gtgcaaaagg atggtcaaac
    24481 ctatgctctt gctaaggaag agggccaaca tacagtaggg gatacggtca aaggttttgc
    24541 atacacggat atgaagcaaa aactccgcct gacaacctta gaagtgactg ccactcagga
    24601 ccaatttggt tggggatgtg tcacagaggt tcgtaaggac ttgggtgtct ttgtagatac
    24661 aggccttcct gacaaggaaa tcgttgtgtc actcgatatt ctccctgagc tcaaggaact
    24721 ctggcctaag aagggcgacc aactctacat ccgtcttgaa gtggataaga aagaccgtat
    24781 ctggggcctc ttggcttatc aagaagactt ccaacgtctt gctcgtcctg cctacaacaa
    24841 catgcagaac caaaactggc cagccattgt ttaccgtctc aagctgtcag gaacttttgt
    24901 ttacctacca gaaaataata tgcttggttt tattcatcct agcgagcgtt acgcagagcc
    24961 acgtttgggg caagtattag atgcgcgcgt tattggtttc cgtgaagtgg accgcactct
    25021 gaacctctcc ctcaaaccac gctcctttga aatgttggaa aacgatgctc agatgatttt
    25081 gacttatttg gaaagtaatg gcggtttcat gaccttaaat gataagtcat ctccagacga
    25141 catcaaggca acctttggca tttctaaagg tcagttcaag aaagctttag gtggtcttat
    25201 gaaggctggt aaaatcaagc aggaccagtt tgggacagag ttgatttagg gaggcttatg
    25261 agaaaatcat tttacacttg gctcatgacc gagcgcaatc ctaaaagtaa cagtcccaaa
    25321 gcaattttgg cagacctcgc ttttgaagag gcagcttttc caaaacatac agatgatttt
    25381 gatgaggtca gtcgcttttt ggaggagcat gccagtttct cttttaacct aggagatttt
    25441 gacagcattt ggcaggaata tctagaacac tagcatttat tcattgggtt tgggctagta
    25501 atttctccat ccctctgcta taataaaaag aaataaaagg attagagagg ttctttattt
    25561 gaaggaacat tcaatagaca ttcaactgag tcatccagat gacctgtttc atctttttgg
    25621 ttccaatgaa cgccatcttc gtttgatgga agaagagctt gatgttgtga ttcatgctcg
    25681 tacggagatt gtccaggttt tgggagaaga gtctgcctgt gaggaagccc gtcaagttat
    25741 tcaggctttg atggtcttgg taaatcgtgg gatgaccgtt ggtacgccag atgtagtcac
    25801 tgcgattagc atggtcaaaa atgatgaaat tgacaagttt gtcgcccttt acgaagaaga
    25861 aattatcaaa gataatactg ggaaacctat ccgtgtcaaa accctagggc aaaagcttta
    25921 tgtggacagt gtcaaacagc atgatgtgac ctttggaatt gggccagcag gtacagggaa
    25981 gaccttcctt gcagtgacct tggcagtgac tgcccttaaa cgtgggcaag tcaagcgaat
    26041 tatcctaact cgtccagcgg tggaagcggg agagagtctt ggatttcttc cgggtgatct
    26101 taaggagaag gtggatcctt accttcgtcc tgtttacgat gccttgtatc aaattcttgg
    26161 gaaagaccaa acgactcgtc tcatggagcg tgaaattatc gaaattgcgc cccttgccta
    26221 tatgcgtggc cggaccttgg atgatgcctt tgtcattctc gatgaggcgc aaaacacgac
    26281 catcatgcag atgaagatgt tcttgacgcg tttaggcttt cattctaaga tgattgtcaa
    26341 tggagatatc agtcagattg acctgccacg taatgtcaag tccggtttga ttgatgctca
    26401 agagaaactc aagaacatcc atcagattga ctttgttcat ttttcagcca aggatgtggt
    26461 tcgccatcca gttgtcgctc agattatccg agcctatgaa tattctactg aagttgcaca
    26521 cgactgattt tgaggaagtt cgcctgcaaa agaatatact tttgagagag gaaaatccag
    26581 ttgtataggc taaaggtttt atccaaaggt ttgagacaac gattaggcac gatggaaaga
    26641 acttttatgt ggctgatgac gatcagtgca tcttcctgtg tcataatcac agggcacaag
    26701 aaagtaggaa tttgaaaaga tgattgacca actatctaag tattacagtt gtaggatact
    26761 aactgaaaag gatattccaa gtattttatc tttatatgaa agtaatcctc tgtattttca
    26821 gcattgtcca ccagagccaa attttgcaac tgtaaaagag gacatgcttt gtctacctga
    26881 aggtaaagct aaggctgata agttttttgt tggattttgg aatggatctg accttgtggc
    26941 tgttatggat tttgtctatg catatcctga tgaggagact gtttttattg gtttgtttat
    27001 ggttgatcaa gcctatcaga ggaaagggat tggtagtcat attgtgacag aagcactagc
    27061 ttattttgct aagaactttc gaaaggcacg tttggcttat gttaagggaa atccgcaatc
    27121 tcagcatttt tgggaaaagc agggctttaa atcaattgga tgcgaggtta agcaagaact
    27181 ctatacggtt gttatcgctg aacagagcct agaagattag aaatggcatc aagtaagaac
    27241 tatttggaat ttgttttgga acaattatca ggattagatg atgtgactta ccgttccatg
    27301 atgggggagt atattcttta cttccgcggc aagattattg gcggcattta tgacgatcgc
    27361 tttttagtta aacccgtgca agcagtctta gataagattg accaatcttc ttttgagttt
    27421 ccatacaaag gtgccaaaga aatgatttga gtggaagaac ttgataataa gatgtttcta
    27481 taagacctga ttttagctat gtataaccaa ctgccaacgc ccaaacctaa aaagaaaaag
    27541 caagggtgaa cgaagtaaaa aagaagtctg ctaaggccct gtctttgcac gggtaaaatt
    27601 ttatatataa aaagaagctg ggactaaaga gctcagcttc ctttggttta tataattgtc
    27661 attacaagac gaagtggttg ggcgaaactc tgttgacttt attcaattta gagtttctta
    27721 tgcacaattg agtctggaac gaaagtctcc agttgcaaag tatacagtat aataaaccaa
    27781 cgatgtaata gctgatgaca caaagcacag tgggtaggac ttgcgaagtc acccttttct
    27841 tttcaaaatt tatactaaat cattgatatc agtgtagtca cgattaagtc cttgagcaac
    27901 tggtaggcta gtcaagtaac cttgataagt ggtcacacct tgacgcaagc cttcatcttc
    27961 agagattgct tgtgcgaatc ctttgccagc caaagcttcg atataaggaa gagtgacatt
    28021 ggttagggcg atggttgaag tgcgggtaac cgcaccaggg atattggcaa cggcatagtg
    28081 gagaacaccg tgtttttcat agacgggttc atcgtgcgtt gtcacacggt cagctgtttc
    28141 gataaggcca ccttggtcaa cagcaacgtc aacgatacag agcctggacg catttgtttg
    28201 accatctcat ctgtcaccaa ttccggtgct tttgcaccag ggatgagaat ggctccaatc
    28261 accacatcag catctctcac acttgcttca atgttgaatg aattagatat aagagtttga
    28321 atttgacttc caaagacttc ttctagaact gagagacgct tggcactaat atctaaaata
    28381 gtcacttgag caccaagacc aagggcgatg cgggcagcat gtgtaccgac gacaccatca
    28441 ccgatgatag ttacttttcc ttttggaaca cctggtacac caccaggtag aacaccagag
    28501 ccaccagctt gcttagtaag gaagtgagct ccgatttaaa cagccatacg acctgcaacc
    28561 tcactcatag gaacgaggag cggtagttgt ccttgattgt cacgaacagt ttcataggca
    28621 attcctgttg tttttgctgc taacatagca tctgctaatt ctggagcagc ggccatgtgc
    28681 aagtaggtga agagaagaag atcgtcgcgc aagtaaccgt attcagaact taaaggttct
    28741 tttactttca caaccaactc tgctgcccaa gcttcaccag cagtagcgac aatctcagct
    28801 ccttgctttt gatagtcagc atcagtaaag ccagaaccga gaccagcatt tgtttcgata
    28861 aggacacgat gaccacgact aactaagcta tgaacacctg caggtgtgag ggcgacacgg
    28921 ttttcgttat ttttaatttc ttttgggatt ccgattaaca ttgagataac ctacctttca
    28981 attgacggtc ttgttttggt tgtcacattc cagttcataa atcaaaaatg tgacggtttc
    29041 attgtatatg aaaccgcttc aaaaatcaag aaaaacttgt catccaaatt tttttatgct
    29101 agactagtga aaatcaagct ctaatggagg gaaaagtatg gaatcaatat ttgtgaaatt
    29161 tgcccagtat ccgtctatag aaacggagcg tttattgctt agacctgtaa ctttggatga
    29221 tgcggaagca atgtttgact atgcctcgga caagggtaat acacgttaca cttttccaac
    29281 caatcaaagc ttggaagaaa ccaagaataa cattgctcag ttctacttgg ctaatccctt
    29341 gggacgttgg ggaatagaac taaaaagcaa tggcaaattt atcggaacaa ttgatttgca
    29401 caagattgat cctgttctta agaaggtagc tattggttat attatcaacc aaacgtattg
    29461 gaatcaagga ttaacgacag aaaccaatcg tgctgtgatt gagctagctt ttgagaagat
    29521 aggaatgaat aagttagttg ctttatacga taaggctaat cccgcatcag gaaaggtcat
    29581 ggagaaatca ggaatgcgtt tttcccatgc agaaccatat gcttgtatgg accagcatga
    29641 aaaaggccga atcgtgacaa gagttcatta tgtcttgacc aaggaagact attttgcaaa
    29701 taaataagca gttgaaaaga aatttttcga ctgttttttc ttcctcttac gaataatcta
    29761 agagaggaga aaatatggaa gcaattatcg agaaaatcaa agagtataaa atcatcgtca
    29821 tctgtactgg tctgggcttg cttgtaggag gatttttcct gctaaaacca gctccacaaa
    29881 cacctgtcaa agagacgaat ttgcaggctg aagtcgcagc tgtttccaag gatttggtat
    29941 ccgaaaagga agtgaacaag gaagaaaagg aagaacccct tgaacaagat ctaatcacag
    30001 tagatgtcaa aggtgctgtc aaatcgccag ggatttatga cttgcctgta ggtagtcgag
    30061 tcaatgatgc tgttcagaag gctggtggct tgacagagca agcagacagc aagtcgctca
    30121 atctagctca gaaagttagt gatgaggctc tggtttacgt tcctactaag ggagaagaag
    30181 cagttagcca acagactggt ttggggacag cttcttcaat aagcaaggaa aagaaggtca
    30241 atctcaacaa ggccagtctg gaagaactca agcaggtcaa gggactggga ggaaaacgag
    30301 ctcaggacat tatcgaccat cgtgaggcaa atggcaagtt caagtcagta gacgagctca
    30361 agaaggtctc tggcattggt ggcaaaacaa tagaaaagct taaagactat gttacagtgg
    30421 attaagaatt tctctattcc cctaatttac ctgagttttc tattactttg gctttattac
    30481 gctattttct cagcatctta tcttgctttg ttgggctttg tttttctgct agtctgtctc
    30541 tttatccaat ttccgtggaa atctgctggt aaagttctaa taatttgcgg aatctttgga
    30601 ttttggtttg tttttcaaaa ttggcaacag agtcaagcga gtcaaaatct ggcggattct
    30661 gttgaaaggg tacggatttt gcctgatact attaaggtta atggtgatag tctatccttt
    30721 cgtggcaagt ctaacggtcg tgctttccaa gtctattata aactccagtc cgaggaggag
    30781 aaagaagcct ttcaagcttt aaccgacctg catgagatag gactagaagg gaagctttcg
    30841 gagccagaag ggcagagaaa ttttggtggc tttaattacc aagcctatct gaagactcag
    30901 ggaatttacc agactctcaa tatcaaaaca atccagtcac ttcaaaagat tggcagttgg
    30961 gatataggag aaaacttgtc cagtttacgt cgaaaggctg tggtttggat taagacgcac
    31021 tttccagacc ctatgcgcaa ttacatgaca ggactcttgc tgggacatct ggacaccgac
    31081 tttgaggaga tgaatgagct ttattccagt ctaggaatta tccacctctt tgccctatct
    31141 ggcatgcagg taggtttttt catgaatgga tttaagaaac ttctcttgca attgggcttg
    31201 acccaagaaa agttgaaatg gctgacttat cccttttccc ttatctatgc gggactaact
    31261 ggattttcag catcggttat tcgcagtctc ttgcaaaagc tactggctca acatggggtt
    31321 aagggcttgg ataattttgc cttgacggtg cttgtcctct ttattgtcat gccaaacttt
    31381 ttcttgacag caggaggagt cttgtcctgc gcttatgctt ttatcctgac catgaccagc
    31441 aaagaagggg aggggctcaa ggctgttgct agtgaaagtc tagtcatctc cttgggcata
    31501 ttgcccattc tatccttcta ttttgcggaa tttcaacctt ggtctatcct tttgaccttt
    31561 gtcttttcct ttctatttga cttgaccttc ttaccgctct tgtctatttt atttgtcctt
    31621 tcctttctct atccagtcat tcagctgaac tttatctttg aatggttgga gggcattatt
    31681 cgcttggtgt cacaggtgac aagtagacct ctggtctttg gacaacccaa tgcatggttt
    31741 ttaatcctat tgttaatttc cttggctttg gtctatgatt tgagaaaaaa cattaaaaag
    31801 ctaacggtat tgtgcttatt gattacaggg ctctttctcc tgaccaagca tccactggaa
    31861 aatgaaatca ccatgctgga tgtggggcaa ggagaaagta ttttcctacg ggatgtaact
    31921 gggaaaacca ttctcataga tgtaggtggt aaggcagaat cttataagaa aatcgaaaaa
    31981 tggcaagaaa agatgacgac cagcaatgcc cagcgaacct tgattcccta tctcaaaagt
    32041 cgaggagtag ttaagattga ccagctaatt ttgactaaca cggacaagga gcatgttgga
    32101 gatttgtcag aggtgactaa ggctttccat gtaggggaga ttctagtatc aaaagacagt
    32161 ctgaaacaga aggaatttgt ggcagaacta caggtgactc aaacaaaggt gcgtagtatg
    32221 acagtagggg agtacttgcc cattttcgga agtcagttag aagtcctatc tccaagggaa
    32281 attggatatg gaggtcatga agattccctg gttctttatg ggaaactctt gaataatcac
    32341 tttctcttca taggaaattt ggaggagaaa ggagagaagg acttgctgaa gtattatcca
    32401 gacttgaaag taaatgtttt gaaagctagc caacatggca ataaaaaatc atcaagtcca
    32461 gcctttctag aaaaactcaa accagagctt actcttatct cagttggaaa gagcaatcga
    32521 atgaaactcc cccatcagga aacattgaca cgactggaag gtatcaatag caaagtttat
    32581 cgaactgacc agcaaggagc tatacgtttt aaggggttgg atagttggaa aatcgaaagt
    32641 gttcgatagg aaggataaat gttgtagatt agtgaaataa actaaaaatt tgttgcataa
    32701 taatgataaa aatggtataa tgaaaacgta ttcaatattg aggatataaa atcattaaaa
    32761 atcagcaaaa gttgttttat tagttagttt ataatctatt ggtcttcttc agtccagtgt
    32821 atctgctgtg acagccacta aaagttacaa gtatgattgg aatacggttt tggaatatag
    32881 taccaactat cacgaccatc agtatgcttg gattccggaa tggtctcgtt attacagcta
    32941 ttctgagtat aaagttggcg gaggctggaa ctacgctcgt tatgaggtca taaactacta
    33001 tactggaggt tattaatcct taaagagtga gaaaaggagg gctggatatg ttaaatctta
    33061 ctcatgttac cttaaaaacg cgacaagtca tcttgcaaga tgcggatttt acctttaaaa
    33121 agggtaggat ttatggcctt cttgctatca atggctcggg aaagacgaca ctattccgag
    33181 ctatgagcaa gttgcttccc cttagtagtg gacacatcgc agttcctcct tctttgtttt
    33241 attatgagag cgttgaatgg ctggatggaa acttaagtgg gatggactac cttcgtctca
    33301 taaaaaacat ctggaagtca gacctaaact tgagagatga aatcgcctac tgggaaatgg
    33361 ctgactatat cagtcttccc atccgcaagt attccttagg gatgaagcaa cgcttggtga
    33421 ttgctatgta ttttctcagt caggccaaat gctggctcat ggatgagatt acaaatggct
    33481 tagacgagta ttatcgacag aagttttttg ataggctagc acaaatcgat agacaagaac
    33541 agctggttct tttaagttcc cactataagg aagagttggt tgatatctgc gatagagtag
    33601 taaccattca tcaggggcag atagaagagg tttagtttat gaaagatgtt agtctatttt
    33661 tattgaaaaa agttttcaaa agtcgtttaa actggattat cttactttta tttgcatctg
    33721 tactcggtgt taccttttat ttaaatagtc agactgcaaa ctcacacagc ttggagagca
    33781 ggttggaaag tcgcattgca gccaacgaga gggctatcaa tgaaaatgaa gagaaactct
    33841 cccaaatgtc tgataccagc tcggaggaat accagtttgc taaaaataat ttagacgtgc
    33901 aaaaaaatct tttgacgcga aagacagaaa ttctaacttt actaaaagaa gggcgctgga
    33961 aagaagccta ctatctgcag tggcaagatg aagagaagaa ttatgaattt gtatcaaatg
    34021 acccgactgc tagctctggc ttaaaaatgg gggttgaccg cgaacggaag atttaccaag
    34081 ccctgtatcc cttgaacata aaagcacata ctttggagtt tccgacccac gggattgatc
    34141 agattgtctg gattttagag gttatcatcc caagcttgtt tgtggttgcg attattttta
    34201 tgctaacaca actatttgca gaaagatatc aaaatcatct ggacacagct cacttatatc
    34261 ctgtttcaaa agtgacattt gcaatatcct ctcttagagt tggagtggga tatgtaactg
    34321 tgctgtttat cggaatctgt ggcttttctt ttctagtggg aagtctgata agtggttttg
    34381 gacagttaga ttatccctac ccaatttata gcttagtgaa tcaagaagta actattggga
    34441 aaatacaaga tgtattattt cctggcttgc tcttagcttt cttagccttt atcgtcattg
    34501 tggaagttgt gtacttgatt gcttactttt tcaagcaaaa aatgcctgtc ctctttcttt
    34561 cactcattgg gattgttggc ttattgtttg gcatccaaac aattcagcct cttcaaagga
    34621 ttgcacatct gattcccttt acttacttgc gttcagtgga gattttatct ggaagattat
    34681 ctaagcagat tgataatgtc gatctaaatt ggagcatggg gatggtctta cttccttgcc
    34741 tgattatcct tttgttagtg gggattctat ttatcgaaag atggggaagt tcacgtaaaa
    34801 aggaagtttt taaagtttag ttttcctata gggaagctaa agaaaaacta acatagggag
    34861 agaatcaact tggttctctc tttttgattc gaaaaccaaa ccaaaatata aacacaaact
    34921 tttcaaaaaa taacttttta tcttgacaag agctagaaaa cttggtatca tataaaagtt
    34981 gagaaaagca gaagtgagag cttctcgcct tgtgacatta agttgcctgg ccctacggat
    35041 gaaaagtttc gaagaaacgc tatcataacg tgcgggcttg tatatttacg agtccgctat
    35101 tgtttttctc taataaaaca aaagaggtga aaaccatagc aaagcaagac ttattcatca
    35161 atgatgagat tcgtgtacgt gaagttcgct tgattggtct tgagggagaa cagctaggca
    35221 tcaagccact cagtgaagcg caagctttgg ctgataacgc taatgttgac ctagtattga
    35281 ttcaacccca agccaaaccg cctgttgcaa aaattatgga ctacggtaag ttcaaatttg
    35341 agtaccagaa gaagcaaaaa gaacaacgta aaaaacaaag cgttgttact gtgaaagaag
    35401 ttcgtctaag tccaactatt gacaagggtg actttgatac aaaacttcgt aatgcacgta
    35461 agttccttga aaaaggaaat aaagttaagg tatctattcg ctttaagggt cgtatgatta
    35521 cccataaaga gattggtgca aaagttttag ccgagtttgc tgaagcaact caagatattg
    35581 ccatcatcga acaacgtgct aaaatggatg gacgtcaaat gttcatgcaa ttggcgccag
    35641 cgactgacaa aaaataattg tcagaaagtt aaataaagga gaaaaaatca tgccaaaaca
    35701 aaaaacacac cgcgcatcag ctaaacgttt caaacgtaca ggttctggtg gacttaaacg
    35761 tttccgtgct tacacttctc accgtttcca cggaaaaacc aagaaacaac gtcgtcatct
    35821 tcgtaaagca tctatggtgc attcaggaga ttacaaacgt atcaaagcaa tgcttactcg
    35881 cttgaaataa tagcttgact gtaagtaaac aattctagga aatatttgga ggaaataaaa
    35941 tatggcacgt gttaaaggtg gcgttgtatc acgcaaacgt cgtaaacgta ttcttaaatt
    36001 agcaaaaggt tactatggag ctaaacacat cttgttccgt actgcaaaag aacaagtaat
    36061 gaactcttac tactatgcat accgtgaccg tcgtcagaaa aaacgtgact tccgcaaatt
    36121 gtggattact cgtatcaatg cggcagctcg tatgaacgga ctttcatact cacaattgat
    36181 gcatggtttg aaattggctg agatcgaagt taaccgtaaa atgcttgctg acttggctgt
    36241 taacgatgca gtagctttca cagctcttgc agatgcagct aaagcaaaac ttggtaaata
    36301 acaactgatg agactggaac aggattgtcc agtcttttta aaaataaagg agaaagatat
    36361 ggcttcaaaa atgctacaca cttgcttacg agtagaaaat cttgaaaaat caatcgcatt
    36421 ttatcaagat gcttttggtt ttaaagaatt gcgtcgcaga gattttccag accatgcctt
    36481 cacgattgtc tatctaggtc ttgagggtga tgattatgag ttggagttga cttataacta
    36541 cgatcacggt ccgtatgtgg ttggtgatgg gtttgcccat atcgccctca gtacacctga
    36601 tcttgaggca cttcatcaag aacacagtgc aaaaggctat gaagtgactg agccaaatgg
    36661 tctaccagga actacaccaa actattactt tgttaaagac cctgatggat ataaggtcga
    36721 agtcattcgt gaaaaataat ttcgtgcaag ttaagtagaa tattcgtttt ctacttgact
    36781 ttttttagct gaaagagtat actaataaaa attcaacctt taaggggagt ccagagagac
    36841 tcacaaggtg tcagataaaa gaatagtgca attttctaga ggagactttt tgagtgtgct
    36901 ctcttgtgtt gtacgatttt aactgaggcc ttgcactagc aaggtctttt ctttatctgg
    36961 tccccttaaa atttaaggag gaaaagttat gaatctcaca tgtaagaagc gtttgggtgt
    37021 cattcggttg gaaaccatga aggtggttgc acaagaggaa atcgcgccag caatctttga
    37081 attagtccta gaaggagaaa tggttgaagc catgcgagca ggccaatttc ttcatctgcg
    37141 tgtaccggac gatgcccatc tcttacgtcg tcctatttca atttcgtcta ttgacaaggc
    37201 aaacaagcag tgtcacctca tttatcggat tgagggagct gggactgcaa ttttttcaac
    37261 cttaagtcag ggagacactc ttgatgtgat ggggcctcag ggaaatggtt ttgacttgtc
    37321 tgaccttgat gagcagaatc aggttctcct tgttggtggt gggattggtg ttccaccctt
    37381 gcttgaggtg gccaaggaat tgcatgaacg tggagtgaaa gtagtgacag tcctcggttt
    37441 tgctaataag gatgctgtta ttttgaaaac ggaattggct cagtatggtc aggtctttgt
    37501 aacgacagat gatggttctt atggcatcaa gggaaatgtt tccgttgtta tcaatgattt
    37561 agatagtcag tttgatgctg tttactcgtg tggggctcca ggaatgatga agtatatcaa
    37621 tcaaaccttt gatgatcacc caagagccta tttatctctg gaatctcgta tggcttgtgg
    37681 gatgggagct tgctatgcct gtgttctaaa agtaccagaa agcgagacgg tcagccaacg
    37741 cgtctgtgaa gatggtcctg ttttccgcac aggaacagtt gtattataag gagaaaatta
    37801 tgactacaaa tcgattacaa gtgtctctac ctggtttgga tttgaaaaat ccgattattt
    37861 cagcatcagg ctgttttggc tttggacaag agtatgccaa gtactatgat ttagaccttt
    37921 taggttctat tatgatcaag gcgacaaccc ttgaaccacg ttttgggaat ccaactccaa
    37981 gagtggcaga gacgcctgct ggtatgctca atgcaattgg cttgcaaaat cctggtttag
    38041 aggttgtttt ggctgaaaag ctaccttggc tggaaagaga atatccaaat cttcctatta
    38101 ttgccaatgt agctggtttt tcaaaacaag agtatgcagc tgtttctcat gggatttcca
    38161 aggcaactaa tgtaaaagct atcgagctca atatttcttg tcccaatgtt gaccactgta
    38221 atcatggact tttgattggt caagatccag atttggctta tgatgtggtg aaagcagctg
    38281 tggaagcctc agaagtgcca gtttatgtca aattaacccc gagtgtgacc gatatcgtta
    38341 ctgtcgcaaa agctgcagaa gatgcgggag caagtggctt aactatgatc aatactctgg
    38401 ttggaatgcg ctttgacctc aaaactagaa aaccaatctt ggccaatgga acaggtggaa
    38461 tgtctggtcc agcagtcttt ccagtagccc tcaaactcat ccgccaagtt gcccaaacaa
    38521 cagacctgcc tatcattgga atgggaggag tggattcggc tgaagctgcc ctagaaatgt
    38581 atctggctgg ggcatctgct atcggagttg gaacagctaa ctttaccaat ccttatgcct
    38641 gccctgacat catcgaaaat ttaccaaaag tcatggataa atacggtatt agcagtctgg
    38701 aagaactccg tcaggaagta aaagagtctc tgaggtaaac tgcaatcaat ctgttcttga
    38761 ttttttatta gtttgtaata tgaatttagg agaattttgg tacaataaaa taaataagaa
    38821 cagaggaaga aggttaatga agaaagtaag atttattttt ttagctctgc tatttttctt
    38881 agctagtcca gagggtgcaa tggctagtga tggtacttgg caaggaaaac agtatctgaa
    38941 agaagatggc agtcaagcag cgaatgagtg ggtttttgat actcattatc aatcttggtt
    39001 ctatataaaa gcagatgcta actatgctga aaatgaatgg ctaaagcaag gtgacgacta
    39061 tttttacctc aaatctggtg gctatatggc caaatcagaa tgggtagaag acaagggagc
    39121 cttttattat cttgaccaag atggaaagat gaaaagaaat gcttgggtag gaacttccta
    39181 tgttggtgca acaggtgcca aagtaataga agactgggtc tatgattctc aatacgatgc
    39241 ttggttttat atcaaagcag atggacagca cgcagagaaa gaatggctcc aaattaaagg
    39301 gaaggattat tatttcaaat ccggtggtta tctactgaca agtcagtgga ttaatcaagc
    39361 ttatgtgaat gctagtggtg tcaaagtaca gcaaggttgg ctttttgaca aacaatacca
    39421 atcttggttt tacatcaaag aaaatggaaa ctatgctgat aaagaatgga ttttcgagaa
    39481 tggtcactat tattatctaa aatccggtgg ctacatggca gccaatgaat ggatttggga
    39541 taaggaatct tggttttacc tcaagtttga tggcaaaatg gctgaaaaag aatgggtcta
    39601 cgattctcat agtcaagcct ggtactactt caaatccggt ggttacatga cagccaatga
    39661 atggatttgg gataaggaat cttggtttta tcttaaatct gatgggaaaa tagctgaaaa
    39721 agaatgggtc tacgattctc atagtcaagc ttggtactac ttcaaatccg gtggttacat
    39781 gacagccaat gaatggattt gggataagga atcttggttt tacctcaaat ctgatgggaa
    39841 aatagctgaa aaagaatggg tctacgatta tcatagtcaa gcctggtact acttcaaatc
    39901 tggtggctac atggcgaaaa atgagacagt agatggttat cagcttggaa gcgatggtaa
    39961 atggcttgga ggaaaagcta caaatgaaaa tgctgcttac tatcaagtag tgcctgttac
    40021 agccaatgtt tatgattcag atggtgaaaa gctttcctat atatcgcaag gtagtgtcgt
    40081 atggctagat aaggatagaa aaagtgatga caagcgcttg gctattacta tttctggttt
    40141 gtcaggctat atgaaaacag aagatttaca agcgctagat gctagtaagg actttatccc
    40201 ttattatgag agtgatggcc accgttttta tcactatgtg gctcagaatg ctagtatccc
    40261 agtagcttct catctttctg atatggaagt aggcaagaaa tattattcgg cagatggcct
    40321 gcattttgat gattttaagc ttgagaatcc cttccttttc aaagatttaa cagaggctac
    40381 aaactacagt gctgaagaat tggataaggt atttagtttg ctaaacatta acaatagcct
    40441 tttggagaac aagggcgcta cttttaagga agccgaagaa cattaccata tcaatgctct
    40501 ttatctcctt gcccatagtg ccctagaaag taactgggga agaagtaaaa ttgccaaaga
    40561 taagaataat ttctttggca ttacagccta tgatacgacc ccttaccttt ctgctaagac
    40621 atttgatgat gtggataagg gaattttagg tgcaaccaag tggattaagg aaaattatat
    40681 cgatagggga agaactttcc ttggaaacaa ggcttctggt atgaatgtgg aatatgcttc
    40741 agacccttat tggggcgaaa aaattgctag tgtgatgatg aaaatcaatg agaagctagg
    40801 tggcaaagat tagtactata agtgaatatg atttgagtga atagtaagtt aaaaatcctg
    40861 atttcaagta aaatcaggat tttttcatgg atgcaatttt tttggagtct ggtgtgacgc
    40921 ggagggtctt ttgtcctgtg taagtgacaa agccgggttt tccaccagtt ggtttattga
    40981 gttttttgac ttcaatcata tctacctgca ccagattcga caggcgccct tgagagaagt
    41041 aggcagctaa ctctgctgcg tctgtcttga ctgcatcaga tgggtcaaga tttcctgaga
    41101 tgacaacatg gcttccagga atgtccttag catggaacca aagttcctcc ttgcgggcca
    41161 ttttaaaggt caattcctca ttttgaagat tgtttcgtcc gacatagatg atggttttgc
    41221 catcgcttgc tagatattgt tctagttttt tgcgtttctg gattttctcc cgttgtcttc
    41281 tgcggataaa acctgtttga atcaattctt cacggatttc agcgatttct tccagtccag
    41341 cttggttgag gacggtttct acactttcca gatagagaat agtggctttg gtttcttcaa
    41401 tcaaatcagt caagtatttg acagcttctt tgagtttctg ataccgttta aaatagcgtt
    41461 gggcattctg gttgggagtc agagccttat caagcgcaat catgataggt tggttggtat
    41521 agtagttgtc taggataacc tggtcttggt cgttaggcac ttggtggagg aaggttgtca
    41581 gcaattctcc tttttgacga aattcttcag cgttgtctgt cgccagtaac tctttttcct
    41641 gttttttgag tttgtgtcgg tttttctgaa gttcattttc aacacgacga atcagttcac
    41701 tggcctgttg tttgacgcgg tcgcgctcag ccttattctt atagtaggtg tccaacaaat
    41761 cagaaagatt tgcaaaaggc tctcccgcct gatttgcaaa aggaactgga ctgaaggaag
    41821 tctcagtcaa gcatggcttg gtttcttgat tgaaaaaatt tcggaaagcg gaaagttttt
    41881 cactaaccag tatcctttcc aattcatttg ccgtatcgcg tcccagacct tgaaagaggc
    41941 tttgaagatt ttttgctgtt agttcttggg tttgcaggat ttcaaagagc ttttcatcct
    42001 tgatagtaaa aggattgaga gattctgtac ttggcggagc gatataggtc gatcctggaa
    42061 gtaaggtgcg gtagctattt tgtgaaaaac cgacgtgttt gataacttcg aggattttat
    42121 gactgctttt atcgaccagt agaatattac tgtgtttccc cataatttcg ataatcaagg
    42181 tagcctggat atggtctcca atctcgtttt tattggaaac tgtcatttcc acaatacggt
    42241 cattttccac ttgctcaatc gactcaatca gggccccctg caaatacttt ctcaaaacca
    42301 tgataaaggt agaaggttgg gctggatttt caaaagtcgt ttgggtcagc tgaatgcgtc
    42361 caaaaactgg atgggcagaa aggagcaggc gatggctttg gcgattgctg cggatttgca
    42421 agaccaactc ttgttcaaaa ggctgattga ttttctggat gcgaccattc actaattcgc
    42481 ttcgcaattc ctcaactatg tggtgtaaaa aaaatccgtc aaatgacatc gttctctcct
    42541 tgtgattgta ttccatagta ttatatcaaa aaggtagaat aaaatcatgg aaatgtggta
    42601 taataaagcc aagtaaagag aaacgagaag cacatgtata ttgaaatggt agatgaaact
    42661 ggtcaagttt caaaagaaat gttgcaacaa acccaagaaa ttttggaatt tgcagcccaa
    42721 aaattaggaa aagaagacaa ggagatggca gtcacttttg tgaccaatga gcgtagtcat
    42781 gaacttaatc tggagtaccg tgacaccgac cgtccgacag atgtcatcag ccttgagtat
    42841 aaaccagaat tggaaattgc ctttgacgaa gaggatttgc ttgaaaatcc agaattggca
    42901 gagatgatgt ctgagtttga tgcctatatt ggggaattgt tcatctctat cgataaggct
    42961 catgagcagg ccgaagaata tggtcacagc tttgagcgtg agatgggctt cttggcagta
    43021 cacggctttt tacatattaa cggctatgat cactatactc cggaagaaga agcggagatg
    43081 ttcggtttac aagaagaaat tttgacagcc tatggactca caagacaata aacgaaaatg
    43141 gaaaaatcgt gacttgatat ccagtttaga atttgctttg acaggtattt ttactgctat
    43201 caaggaagaa cgcaatatgc gaaaacacgc agtgacggct ctagtggtca tccttgcagg
    43261 ttttgttttt caggtgtcac gaatcgaatg gctctttctc ctattgagca ttttcttggt
    43321 agtagccttt gagattatca actctgctat tgaaaatgtg gtggatttgg ccagtcacta
    43381 tcacttttcc atgctggcta aaaatgccaa ggatatggcg gctggcgcgg tattagtggt
    43441 ttctcttttt gcagccttaa caggcgcatt gatttttctc ccacgaatct gggatttatt
    43501 attttaaaca gtaagaggaa attatgactt ttaaatcagg ctttgtagcc attttaggac
    43561 gtcccaatgt tgggaagtca acctttttaa atcacgttat ggggcaaaag attgccatca
    43621 tgagtgacaa ggcgcagaca acgcgcaata aaatcatggg aatttacacg actgataagg
    43681 agcaaattgt ctttatcgac acaccaggga ttcacaaacc taaaacagct ctcggagatt
    43741 tcatggttga gtctgcctac agtacccttc gcgaagtgga cactgttctt ttcatggtgc
    43801 ctgctgatga agcgcgtggt aagggggacg atatgattat cgagcgtctc aaggctgcca
    43861 aggttcctgt gattttggtg gtgaataaaa tcgataaggt tcatccagac cagctcttgt
    43921 ctcagattga tgacttccgt aatcaaatgg actttaagga aattgttcca atctcagccc
    43981 ttcagggaaa taacgtgtct cgtctagtgg atattttgag tgaaaatctg gatgaaggtt
    44041 tccaatattt cccgtctgat caaatcacag accatccaga acgtttcttg gtttcagaaa
    44101 tggttcgcga gaaagtcttg catctaactc gtgaagagat tccgcattct gtagcagtag
    44161 ttgttgactc tatgaaacga gacgaagaga cagacaaggt tcacatccgt gcaaccatca
    44221 tggtcgagcg cgatagccaa aaagggatta tcatcggtaa aggtggcgct atgcttaaga
    44281 aaatcggtag catggcccgt cgtgatatcg aactcatgct aggagacaag gtcttcctag
    44341 aaacctgggt caaggtcaag aaaaactggc gcgataaaaa gctagatttg gctgacttgg
    44401 gctataatga aagagaatac taagtagagg taggctcatg cctgcttctt gtttttacag
    44461 aaggaggact tatgcctgaa ttacctgagg ttgaaaccgt ttgtcgtagc ttagaaaaat
    44521 tgattatagg aaagaagatt tcgagtatag aaattcgcta ccccaagatg attaagacgg
    44581 atttggaaga gtttcaaagg gaattgccta gtcagattat cgagtcaatg ggacgtcgtg
    44641 gaaaatattt gcttttctgc ctgacagaca aggtcttgat ttcccatttg cggatggagg
    44701 gcaagtattt ttattatcca gaccaagtgc ctgaacgcaa gcatgcccat gttttcttcc
    44761 ggtttgaaga tgggggcacg cttgtttatg aggatgtacg caagtttgga accatggaac
    44821 tcttggtgcc tgacctttta gacgcctact ttatttctaa aaaattaggt cctgaaccaa
    44881 gcgaacaaga ctttgattta caggtctttc aagctgccct tgccaagtcc aaaaagccta
    44941 tcaaatccca tctcctagac cagaccttgg tagctggact tggcaatatc tatgtggatg
    45001 aggttctctg gcgagctcag gttcatccag ctagaccttc ccagactttg acagcagaag
    45061 aagcgactgc cattcatgac cagaccattg ctgttttggg ccaggctgtt gaaaaaggcg
    45121 gttccaccat tcggacctat accaatgcct ttggggaaga tggaagcatg caggattttc
    45181 atcaggtcta tgataagact ggtcaagaat gtgtacgctg tggtaccatc attgagaaaa
    45241 ttcaactagg cggacgaggc acccactttt gtccaaactg tcaaaggagg gactgatgag
    45301 aaaaatcatc ggaatcactg ggggaattgc ctctggtaag tcaactgtga caaattttct
    45361 aagacagcaa ggctttcaag tagtggatgc cgacgcagtc gtccaccaac tacagaaacc
    45421 tggtggtcgt ctgtttgagg ctctagtaca gcactttggg caagaaatca ttcttgaaaa
    45481 cggagaactc aatcgccctc tcctagctag tctcatcttt tcaaatcctg aagagcaaaa
    45541 atggtctaag caaattcaag gggagattat ccgtgaggaa ctggctactt tgagagaaca
    45601 gttggctcag acagaagaga ttttcttcat ggatattccc ctactttttg agcaggacta
    45661 cagcgattgg tttgctgaga cttggttggt ctatgtggac cgagatgccc aagtagaacg
    45721 cttaatgaaa agggaccagt tgtccaagga tgaagctgag tctcgtctgg cagcccagtg
    45781 gcctttagaa aaaaagaaag atttggccag ccaggttctt gataataatg gcaatcagaa
    45841 ccagcttctt aatcaagtgc atatccttct tgagggaggt aggcaagatg acagagatta
    45901 actggaagga taatctgcgc attgcctggt ttggtaattt tctgacagga gccagtattt
    45961 ctttggttgt accctttatg cccatcttcg tggaaaatct aggtgtaggg agtgagcaag
    46021 tcgcttttta tgcaggctta gcaatttctg tctctgctat ttccgcggcg ctcttttctc
    46081 ctatttgggg tattcttgct gacaaatacg gccgaaaacc catgatgatt cgggcaggtc
    46141 ttgctatgac tatcactatg ggaggcttgg cctttgtccc aaatatctat tggttaatct
    46201 ttcttcgttt actaaacggt gtatttgcag gttttgttcc taatgcaacg gcactgatag
    46261 ccagtcaggt tccaaaggag aaatcaggct ctgccttagg tactttgtct acaggcgtag
    46321 ttgcaggtac tctaactggt ccctttattg gtggctttat cgcagaatta tttggcattc
    46381 gtacagtttt cttactggtt ggtagttttc tatttttagc tgctattttg actatttgct
    46441 ttatcaagga agattttcaa ccagtagcca aggaaaaggc tattccaaca aaggaattat
    46501 ttacctcggt taaatatccc tatcttttgc tcaatctctt tttaaccagt tttgtcatcc
    46561 aattttcagc tcaatcgatt ggccctattt tggctcttta tgtacgcgac ttagggcaga
    46621 cagagaatct tctttttgtc tctggtttga ttgtgtccag tatgggcttt tccagcatga
    46681 tgagtgcagg agtcatgggc aagctaggtg acaaggtggg caatcatcgt ctcttggttg
    46741 tcgcccagtt ttattcagtc atcatctatc tcctctgtgc caatgcctct agcccccttc
    46801 aactaggact ctatcgtttc ctctttggat tgggaaccgg tgccttgatt cccggggtta
    46861 atgccctact cagcaaaatg actcccaaag ccggcatttc gagggtcttt gccttcaatc
    46921 aggtattctt ttatctggga ggtgttgttg gtcccatggc aggttctgca gtagcaggtc
    46981 aatttggcta ccatgctgtc ttttatgcga cgagcctttg tgttgccttt agttgtctct
    47041 ttaacctgat tcaatttcga acattattaa aagtaaagga aatctagtgc gagtaaaaat
    47101 taatctcaaa tgctcctctt gtggcagtat caattaccta accagtaaaa attcaaaaac
    47161 ccatccagac aagattgagg ttttaaagta ttgtcccaag gaaagaaaag taaccctaca
    47221 tcttgaatct aagtagattt tatggtaaaa taatagggat tttaaggagt ttgatatgta
    47281 taacctatta ttaaccattt tattagtatt atctgttgtg attgtgattg caattttcat
    47341 gcaaccaacc aaaaaccaat ccagcaatgt atttgatgcc agttcaggtg atttgtttga
    47401 acgcagtaaa gctcgcggtt ttgaagctgt aatgcagcgt ttgacaggga ttttagtctt
    47461 tttctggcta gccattgcct tagcattgac ggtattatca agtagataag aaaataatgg
    47521 gcaggactag gtctttgcct ctttttattt ttaaaggatg tttgagaagg ttttacagta
    47581 aaagaaaatt aaaaaatcta gaaagaaaat atgaaagata gaataaaaga atatttacaa
    47641 gacaagggaa aggtgactgt taatgatttg gctcaggctt tgggaaaaga cagttccaag
    47701 gattttcgtg agttgattaa aaccttgtcc ttaatggaaa gaaagcacca aattcgtttt
    47761 gaagaagatg gtagtctgac attagaaatt aagaaaaaac atgagattac cctcaagggg
    47821 atttttcatg cccataaaaa tggctttggc tttgttagtc tggaaggcga ggaggacgac
    47881 ctttttgtag ggaaaaatga tgtcaactat gctattgatg gtgataccgt cgaggtagtg
    47941 attaagaaag tcgctgaccg caataaggga acagcagcag aagccaaaat tattgatatc
    48001 ctagaacaca gtttgacaac agttgtcggg caaatcgttc tggatcagga aaaacctaag
    48061 tatgctggct atattcgttc aaaaaatcag aaaatcagtc aaccgattta tgttaagaaa
    48121 ccagccctaa aattagaagg aacagaagtt ctcaaggtct ttatcgataa atacccaagc
    48181 aagaaacatg atttctttgt cgcgagtgtt ctcgatgtgg tgggacactc aacggatgtc
    48241 ggaattgatg ttcttgaggt tttggaatca atggacattg tatccgagtt tccagaagct
    48301 gttgttaagg aagcagaaag tgtgcctgat gctccgtctc aaaaggatat ggaaggtcgt
    48361 ctggatctaa gagatgaaat tacctttacc attgacggtg cggatgccaa ggacttggac
    48421 gatgcagtgc atatcaaggc tctgaaaaat ggcaatctgg agcttggggt tcacatcgca
    48481 gatgtttctt attatgtgac cgaggggtct gcccttgaca aggaagccct taaccgtgcg
    48541 acttctgttt acgtgacaga ccgagtggtg ccaatgcttc cagaacgact atcaaatggc
    48601 atctgctctc tcaatcccca agttgaccgc ctgacccagt ctgctattat ggagattgat
    48661 aaacatggtc gtgtggtcaa ctataccatt acacaaacag ttatcaagac cagttttcgt
    48721 atgacctata gcgatgtcaa tgatatccta gctggcgatg aagaaaagag aaaaaaatat
    48781 cataaaattg taccaagtat cgaactcatg gccaagcttc atgaaacttt agaaaacatg
    48841 cgtgtgaaac gtggagctct caattttgat accaatgaag cgaagatttt agtggataaa
    48901 caaggtaagc ctgttgatat cgttcttcgg cagcgtggta ttgccgagcg gatgattgag
    48961 tcttttatgt tgatggctaa tgaaacagtt gccgaacatt tcagcaagtt ggatttgcct
    49021 tttatctatc gaattcacga ggagcctaag gctgaaaagg ttcagaagtt tattgattat
    49081 gcttcgagtt ttggcttgcg catttatggg actgccagtg agattagtca ggaggcactt
    49141 caagacatca tgcgtgctgt tgagggagaa tcttatgcag atgtattgtc catgatgctt
    49201 cttcgctcta tgcagcaggc tcgttattcg gagcacaatc acggccacta tggactagct
    49261 gctgactatt atactcactt taccagtcca attcgtcgtt atccagacct tcttgttcac
    49321 cgtatgattc gggattacgg ccgttctaag gaaatagcag agcattttga acaagtgatt
    49381 ccagagattg cgacccagtc ttccaaccgt gaacgtcgtg ccatagaagc tgagcgtgaa
    49441 gtcgaagcca tgaaaaaggc tgagtatatg gaagaatacg tgggtgaaga gtatgatgca
    49501 gttgtatcaa gtattgtcaa attcggtctc tttgtcgaat tgccaaacac agttgaaggc
    49561 ttgattcaca tcactaatct acctgaattt tatcatttca atgagcgtga tttgactctt
    49621 cgtggagaaa aatcaggtat cactttccga gtgggtcagc agatccgtat ccgtgttgaa
    49681 agagcggata aaatgactgg agagattgat ttttcattcg tacctagtga gtttgatgtg
    49741 attgaaaaag gcttgaaaca gtctagtcgt agtggcagag ggcgtggttc aaatcgtcgt
    49801 tcggataaga aggaagacaa gagaaaatca ggacgctcaa atgataagcg taagcattca
    49861 caaaaagaca agaagaaaaa aggaaagaaa cctttttaca aggaagtagc taagaaagga
    49921 gccaagcatg gcaaagggcg agggaaaggt cgtcgcacaa aataaaaagg cacgccacga
    49981 ctatacaatc gtagatacgc tagaggcagg gatggtcctg actggaactg aaatcaagag
    50041 tgtacgagct gctcgaatta atctcaagga tggctttgct caagtgaaaa atggagaagt
    50101 ttggctgagc aatgttcata tcgcgcctta cgaagagggc aatatctgga accaggaacc
    50161 agaacgtcgt cgtaaactcc tgctccataa aaggcaaatt caaaaattgg aacaagagac
    50221 caaagggaca ggaatgacct tagttcccct taaggtctat ataaaagatg gctacgctaa
    50281 gcttctttta ggacttgcca aagggaagca tgactatgac aaacgggagt ctatcaaacg
    50341 tcgtgagcaa aatcgagata tcgcgcgtgt gatgaaagct gttaatcagc gataaaaaga
    50401 ggaattgaaa atggaaaaat tagttgccta taaacgcatg cctttgtgga ataaacaaac
    50461 aatgcctgaa gctgttcagc aaaagcacaa tacaaaagtt gggacttggg ggaaaattac
    50521 tgtcttgaag ggagctctca agtttattga attgacagaa gaaggggaag ttctagctga
    50581 acacctcttt gaagcagggg cagacaatcc aatggcccaa cctcaagcct ggcaccgagt
    50641 ggaagctgcc acagatgatg tggaatggta cttggaattt tattgtaaac ctgaggatta
    50701 ttttgctaaa aaatacaata ccaatcctgt tcattcagag gtcctagagg tcatggagac
    50761 agtgaaacaa gggaaagctt tggatttggg ttgtggtcag gggcgtaatt ctctttttct
    50821 agcccagcaa gattttgatg tgacggctgt agatcaaaat ggactagctc ttgaaatctt
    50881 gcaaagcatt gtggagcagg aagatttgga catgcctgtt ggcctttacg atatcaattc
    50941 agctagcatt gaacaagaat atgattttat cgtttcaaca gttgttctca tgtttctaca
    51001 agcggaccgc attccagcta ttattcaaaa tatgcaggag aaaaccagtg ttggtggtta
    51061 caaccttatc gtttgtgcca tggacacgga ggattatcct tgctcggtta acttcccatt
    51121 cacctttaaa gaaggagaac tggcagacta ttacaaggat tgggaattgg ttaagtacaa
    51181 tgaaaatcca ggccatttgc atcgtcgcga tgagaatggc aatcgtattc aactacgctt
    51241 tgcgacctta ctagctaaga aaatcaagta aacacacatg aagattagga attttcctga
    51301 tcttttttct tttttacgaa tgatatagaa aaggagggaa ttcatgtttg ttgcgagaga
    51361 tgctagggga gaattggtaa atgtgttaga ggataaactt gagaagcaag catacacctg
    51421 cccagcttgt ggaggccagc tccatttgcg tcaaggacca agtgtacgga cgcattttgc
    51481 ccataaatcc ttaaaagact gtgatttttt ctttgaaaat gaaagtccag aacacctggc
    51541 caataaggaa tccctctatc actggttgaa aaaagagaca aaggttcaat tagagtaccc
    51601 gctttcagaa cttaaacaga ttgcggatgt atttgtaaat ggcaatctag ctctagaagt
    51661 tcagtgtagt cccttgcctc agaaagtcct taaagagcga agtgagggct atcgtagtca
    51721 gggttaccaa gtactgtggt tgctgggtca aaaactgtgg ctcaaggagc gtttgactcg
    51781 tctacagcaa ggttttcttt atttcagtca aaacatgggc ttttatgttt gggaattaga
    51841 caaggaaaaa caagttttaa gactcaaata cctgatttac caggatctcc gcggtaaact
    51901 ccattatcaa atcaaggaat tttcctatgg tcaaggtagt ttattggaaa tattgcgtct
    51961 tccctataag agacaaaaaa tatctcattt tacagtttct gaggacaagg acatctgtcg
    52021 ctatatccgg caacaacttt attatcaaaa tctcttttgg atgaaagaac aagcagaagc
    52081 ctatcaaaag ggagaaaata tcctgactta tggactgaaa gaatggtatc cacaaattcg
    52141 accaatagtg ggcaaatttt tccagattga acaagacttg actagctatt atcagcactt
    52201 ttatacctat taccaaaaaa atcctcaaaa tgattggcaa aagctttatc caccagcctt
    52261 ttatcagcaa tatttcttga aaaatatggt agaatagaaa ggatggagga atctaatggt
    52321 attacaaaga aatgaaataa atgaaaaaga tacatgggat ctatcaacga tctacccaac
    52381 tgaccaggct tgggaagaag ccttaaaaga tttaacagaa caattggaga cagtagccca
    52441 gtatgaaggc catctcttgg atagtgcgga taacctacta gaaatcactg aattttctct
    52501 tgaaatggaa cgccagatgg agaagcttta cgtttatgct catatgaaga atgaccagga
    52561 tacacgtgaa gctaagtatc aagagtacta tgccaaggcc atgacactct acagccagtt
    52621 agaccaagcc ttttcattct atgatcctga atttatggag attagcgaaa agcagtatgc
    52681 tgacttttta gaagctcaac caaagctgca ggtttatcaa cactattttg acaagctctt
    52741 gcaaggcaag gatcacgttc tttcacaacg tgaagaagaa ttattggctg gagctggaga
    52801 aatctttggt tcagcaagtg aaaccttcgc tatcttggac aatgcggata ttgtgttccc
    52861 ttatgtccta gacgatgatg gtaaagaagt tcagctatct catgggactt acacacgttt
    52921 gatggagtct aaaaaacgtg aggttcgccg tggtgcctat caagctcttt atgcgactta
    52981 cgaacaattc caacacacct atgccaaaac cttgcaaacc aatgttaagg tgcaaaatta
    53041 ccgtgctaaa gttcgtaact acaagagtgc tcgtcatgca gctctcgcag cgaattttgt
    53101 tccagaaagt gtttatgaca atttggtagc agcagttcgc aagcatttgc cactcttaca
    53161 tcgctatctt gagcttcgtt caaaaatctt ggggatttca gatctcaaga tgtacgatgt
    53221 ctacacaccg ctttcatctg ttgaatacaa ttttacctac caagaagcct tgaaaaaagc
    53281 agaagatgct ttggcagtct tgggtgagga ttacttgagc cgtgtcaaac gtgccttcag
    53341 cgagcgttgg attgatgttt acgaaaatca aggcaagcgt tcaggtgcct actctggtgg
    53401 ttcttacgat accaatgcct ttatgcttct caactggcag gacaatctgg acaatctctt
    53461 tactcttgtt catgaaacag gtcacagtat gcattcaagc tatactcgtg aaacacagcc
    53521 ttatgtttac ggagattact ctatcttttt ggctgagatt gcctcaacta ccaatgaaaa
    53581 tatcttgacg gagaaattat tggaagaagt ggaagacgac gcaacacgct ttgctattct
    53641 caataacttc ctagatggtt tccgtggaac agttttccgc caaactcaat ttgctgagtt
    53701 tgaacacgcc attcaccaag cagatcaaaa tggggaggtc ttgacaagcg atttcctaaa
    53761 taaactctac gcagacttga accaagagta ttatggtttg agtaaggaag acaatcctga
    53821 aatccaatac gagtgggctc gcattccaca cttctactat aactactatg tatatcaata
    53881 ttcaactggc tttgcggccg cctcagcctt ggctgaaaaa attgtccatg gtagtcaaga
    53941 agaccgtgac cgctatatcg actacctcaa ggcaggtaag tcggactatc cacttaatgt
    54001 catgagaaaa gctggtgttg atatggagaa ggaagactac ctcaacgatg cctttgcagt
    54061 ctttgaacgc cgtttaaatg agtttgaagc ccttgttgaa aaattaggat tggcataaaa
    54121 tggttgaatc gtatagtaag aatgctaacc ataacatgcg tcgtcctgtc gtcaaagaag
    54181 aaattgtaga cttgatgcgt cagcgtcaaa agcaggtcac aggtttcttg aaagaattgg
    54241 aagactttgc ccgcaaggaa aatattccta ttattcccca tgaaacggtt gcttatttcc
    54301 gttttcttat ggaaaccatg cagcctaaaa atattctgga aattgggacg gctatcggtt
    54361 tttcagctct cttgatggct gaacatgcgc caaatgctaa gattacaact attgatcgta
    54421 atccagaaat gattggtttt gccaaggaaa attttgccca gtttgacagt cgcaagcaaa
    54481 tcactctcct agagggagat gcggtggatg tcttatctac actgacagag tcttatgatt
    54541 tcgtctttat ggattctgcc aagtctaaat acatcgtctt tctgccagaa atcctcaaac
    54601 atttggaagt tggtggtgtg gttgtcttgg atgatatttt tcaaggtggt gatgttgcca
    54661 aggatattat ggaagtccgt cgtggtcagc gaaccattta tcgaggcctt caaaaattat
    54721 ttgatgcaac cttagacaat ccagaactca ccgcaacatt agtgccttta ggagatggta
    54781 ttctcatgct tcgtaaaaat gtagcagatg ttcaactgtc tgaaagcgaa tgattttcag
    54841 aaaaatttaa gaaaaaatag taaaatagat agagtaacac ttatctcaaa ggagtagaca
    54901 tgaagaaaaa attattggca ggtgccatca cactattatc agtagcaact ttagcagctt
    54961 gttcgaaagg gtcagaagga gcagacctta tcagcatgaa aggggatgtc atcacagaac
    55021 atcaatttta tgagcaagtg aaaaacaacc cttcagccca acaagtcttg ttaaatatga
    55081 ccatccaaaa agtttttgaa aaacaatatg gctcagagct tgatgataaa gaggttgatg
    55141 atactattgc cgaagaaaaa aaacaatatg gcgaaaacta ccaacgtgtc ttgtcacaag
    55201 caggtatgac tcttgaaaca cgtaaagctc aaattcgtac aagtaaatta gttgagttgg
    55261 cagttaagaa ggtagcagaa gctgaattga cagatgaagc ctataagaaa gcctttgatg
    55321 agtacactcc agatgtaacg gctcaaatca tccgtcttaa taatgaagat aaggccaaag
    55381 aagttctcga aaaagccaag gcagaaggtg ctgattttgc tcaattagcc aaagataatt
    55441 caactgatga aaaaacaaaa gaaaatggtg gagaaattac ctttgattct gcttcaacag
    55501 aagtacctga gcaagtcaaa aaagccgctt tcgctttaga tgtggatggt gtttctgatg
    55561 tgattacagc aactggcaca caagcctaca gtagccaata ttacattgta aaactcacta
    55621 agaaaacaga aaaatcatct aatattgatg actacaaaga aaaattaaaa actgttatct
    55681 tgactcaaaa acaaaatgat tcaacatttg ttcaaagcat tatcggaaaa gaattgcaag
    55741 cagccaatat caaggttaag gaccaagcct tccaaaatat ctttacccaa tatatcggtg
    55801 gtggagattc aagctcaagc agtagtacat caaacgaata gtccaaatca atgagtcagg
    55861 gaaaaaactc gacttcagga aaaaatgaag caaacattcc cacaataaaa cgcatagtac
    55921 aaggtttgta ctgcccccca aaaaagttag acaattaatt tatccgaagg atttagttct
    55981 gtattgcaca gagctaagtc cttttagttt tatcttaatt ctcttattgt tgtaataatc
    56041 aatatagtct ataatggctt gttccaattg attaagtgat ttaaatgttt gctcatagcc
    56101 ataaaacatt tcggatttta aaatgccaaa gaaagattcc atcctaccgt tgtcttggct
    56161 gtttcctttg cgtgacatag atgcttgaat tcccttactc tctaggaagc gatgataaga
    56221 atcgtgttgg tattgccagc cttggtcact atggagaatc gtattctcgt agtgcttctc
    56281 tttgaatgcc tgttccaaca
//
LOCUS       DAVKAU010000009        50463 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVKAU010000009 DAVKAU010000000
VERSION     DAVKAU010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50463
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.009"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..494
                     /locus_tag="VWX48_000623"
     CDS             <1..494
                     /locus_tag="VWX48_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEU9171290.1"
                     /translation="FKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQI
                     QNKIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRG
                     LYPEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLI
                     LKK"
     gene            838..2451
                     /locus_tag="VWX48_000624"
     CDS             838..2451
                     /locus_tag="VWX48_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU9171291.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            2581..3207
                     /gene="gmk"
                     /locus_tag="VWX48_000625"
     CDS             2581..3207
                     /gene="gmk"
                     /locus_tag="VWX48_000625"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU9171292.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            3232..3546
                     /locus_tag="VWX48_000626"
     CDS             3232..3546
                     /locus_tag="VWX48_000626"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU9171293.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            3612..6008
                     /locus_tag="VWX48_000627"
     CDS             3612..6008
                     /locus_tag="VWX48_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU9171294.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVFGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            6021..6956
                     /locus_tag="VWX48_000628"
     CDS             6021..6956
                     /locus_tag="VWX48_000628"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU9171295.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            6949..8262
                     /gene="rsmB"
                     /locus_tag="VWX48_000629"
     CDS             6949..8262
                     /gene="rsmB"
                     /locus_tag="VWX48_000629"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU9171296.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            8277..9017
                     /locus_tag="VWX48_000630"
     CDS             8277..9017
                     /locus_tag="VWX48_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU9171297.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            9014..10993
                     /gene="pknB"
                     /locus_tag="VWX48_000631"
     CDS             9014..10993
                     /gene="pknB"
                     /locus_tag="VWX48_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU9171298.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            11108..11866
                     /locus_tag="VWX48_000632"
     CDS             11108..11866
                     /locus_tag="VWX48_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9171299.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            11868..12317
                     /locus_tag="VWX48_000633"
     CDS             11868..12317
                     /locus_tag="VWX48_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9171300.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            12379..12960
                     /locus_tag="VWX48_000634"
                     /pseudo
     CDS             12379..12960
                     /locus_tag="VWX48_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13073..13321
                     /locus_tag="VWX48_000635"
                     /pseudo
     CDS             13073..13321
                     /locus_tag="VWX48_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            13452..14624
                     /locus_tag="VWX48_000636"
     CDS             13452..14624
                     /locus_tag="VWX48_000636"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU9171301.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            14624..15898
                     /locus_tag="VWX48_000637"
     CDS             14624..15898
                     /locus_tag="VWX48_000637"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU9171302.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIAGKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQANSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(15933..16898)
                     /locus_tag="VWX48_000638"
     CDS             complement(15933..16898)
                     /locus_tag="VWX48_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9171303.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(16879..18333)
                     /locus_tag="VWX48_000639"
     CDS             complement(16879..18333)
                     /locus_tag="VWX48_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9171304.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGIYYELDYGRKTN"
     gene            18711..20594
                     /locus_tag="VWX48_000640"
     CDS             18711..20594
                     /locus_tag="VWX48_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9171305.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IGNLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            20743..21630
                     /locus_tag="VWX48_000641"
     CDS             20743..21630
                     /locus_tag="VWX48_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9171306.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(21950..22567)
                     /locus_tag="VWX48_000642"
     CDS             complement(21950..22567)
                     /locus_tag="VWX48_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU9171307.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(22982..23201)
                     /locus_tag="VWX48_000643"
                     /pseudo
     CDS             complement(22982..23201)
                     /locus_tag="VWX48_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23686..23766)
                     /locus_tag="VWX48_000644"
                     /pseudo
     CDS             complement(23686..23766)
                     /locus_tag="VWX48_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            23882..24775
                     /locus_tag="VWX48_000645"
     CDS             23882..24775
                     /locus_tag="VWX48_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171308.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            24772..25971
                     /locus_tag="VWX48_000646"
     CDS             24772..25971
                     /locus_tag="VWX48_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9171309.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMTKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(26324..27091)
                     /locus_tag="VWX48_000647"
     CDS             complement(26324..27091)
                     /locus_tag="VWX48_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171310.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(27108..27803)
                     /locus_tag="VWX48_000648"
     CDS             complement(27108..27803)
                     /locus_tag="VWX48_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171311.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(27808..28173)
                     /locus_tag="VWX48_000649"
     CDS             complement(27808..28173)
                     /locus_tag="VWX48_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9171312.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            28313..28786
                     /gene="nrdR"
                     /locus_tag="VWX48_000650"
     CDS             28313..28786
                     /gene="nrdR"
                     /locus_tag="VWX48_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU9171313.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            28787..29956
                     /locus_tag="VWX48_000651"
     CDS             28787..29956
                     /locus_tag="VWX48_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU9171314.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            29957..30853
                     /gene="dnaI"
                     /locus_tag="VWX48_000652"
     CDS             29957..30853
                     /gene="dnaI"
                     /locus_tag="VWX48_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU9171315.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKFSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            30850..31563
                     /locus_tag="VWX48_000653"
     CDS             30850..31563
                     /locus_tag="VWX48_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU9171316.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            31577..32887
                     /gene="der"
                     /locus_tag="VWX48_000654"
     CDS             31577..32887
                     /gene="der"
                     /locus_tag="VWX48_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU9171317.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRR"
     gene            32978..33313
                     /locus_tag="VWX48_000655"
     CDS             32978..33313
                     /locus_tag="VWX48_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171318.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            33453..33788
                     /locus_tag="VWX48_000656"
     CDS             33453..33788
                     /locus_tag="VWX48_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171319.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     SLFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            33973..34764
                     /locus_tag="VWX48_000657"
     CDS             33973..34764
                     /locus_tag="VWX48_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171320.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIVTYFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFFKIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            34757..35398
                     /locus_tag="VWX48_000658"
     CDS             34757..35398
                     /locus_tag="VWX48_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171321.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            35402..36052
                     /locus_tag="VWX48_000659"
     CDS             35402..36052
                     /locus_tag="VWX48_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9171322.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            36063..36350
                     /locus_tag="VWX48_000660"
     CDS             36063..36350
                     /locus_tag="VWX48_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171323.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGKIDLFS
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            36496..39009
                     /gene="secA"
                     /locus_tag="VWX48_000661"
     CDS             36496..39009
                     /gene="secA"
                     /locus_tag="VWX48_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU9171324.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            39090..40121
                     /locus_tag="VWX48_000662"
     CDS             39090..40121
                     /locus_tag="VWX48_000662"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9171325.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            40123..41154
                     /locus_tag="VWX48_000663"
     CDS             40123..41154
                     /locus_tag="VWX48_000663"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9171326.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            41193..41561
                     /locus_tag="VWX48_000664"
     CDS             41193..41561
                     /locus_tag="VWX48_000664"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU9171327.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            41551..42654
                     /locus_tag="VWX48_000665"
     CDS             41551..42654
                     /locus_tag="VWX48_000665"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU9171328.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            42673..44688
                     /gene="recG"
                     /locus_tag="VWX48_000666"
     CDS             42673..44688
                     /gene="recG"
                     /locus_tag="VWX48_000666"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU9171329.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            45004..45984
                     /locus_tag="VWX48_000667"
     CDS             45004..45984
                     /locus_tag="VWX48_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU9171330.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFYDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            46744..46971
                     /locus_tag="VWX48_000668"
     CDS             46744..46971
                     /locus_tag="VWX48_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171331.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            47259..50141
                     /gene="nanA"
                     /locus_tag="VWX48_000669"
     CDS             47259..50141
                     /gene="nanA"
                     /locus_tag="VWX48_000669"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU9171332.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESM
                     HNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTK
                     EDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT        15110 a         9514 c        11400 g        14439 t
ORIGIN      
        1 tatttaagta tttcgaaaag gatattaaag atgacattct agatactcta aaagtttatg
       61 aagaatcaga aaatattatt taccataaag taattgattt gatgagttat aatgtctatg
      121 attttcctca gatacaaaat aaaatctacc attatttgat taaaagaatt aatgataaaa
      181 gagttgaggg ggttaaaact ttcccagacc caagagaaaa gtctgtatca gatttataca
      241 acttaagtag aaaaggatat ttttctgatt ttgagatttt aaaagatatt gaagaagata
      301 ttcgaggact ttatcctgaa gtagattgga cctggttcca tgatagaagt gatgatgtta
      361 tccatcgtct actagaacat agaactccca ataatattaa aacttatttt tcaaaaaatg
      421 aagaagataa taaattgatt aatgagtata ttttaaaagc tttcgatgag gataaattaa
      481 tacttaagaa ataaattgat acaactaaat aaaaaaagtt aatttatgac aaatttgatc
      541 ttgaagataa gctgtaattt cctaaagtga attttcaaag acttgaaagc aaaatatttg
      601 aatctagtgg aacactattt ggcacaacaa tagaaaatcc atagttgtag aaattcggtg
      661 gaactttttg atagcgacac tgacttatct ccttaaaaaa ccaaggaagt gtaatcctaa
      721 aattcagact aaattcccca aaacatattc tattttaggt ttgtgaaaat cactttttta
      781 tggtagaatg taaaagaatg tatgtcattc ggaataacaa taaaatgagg taaaaacatg
      841 gaaatcatgt cgcttgcgat tgctgttttt gccgtcatca ttggtttagt cattggatat
      901 gtcagcatct cagctaagat gaaatcatct caggaagctg cagagttgat gcttttaaat
      961 gctgaacaag aagcaactaa tttacgtgga caagctgagc gtgaagcgga tttacttgtt
     1021 aatgaagcca aacgtgaaag caagtctctt aaaaaagaag cactattgga ggccaaagaa
     1081 gaagccagaa aataccgtga agaagtggac gctgaattca aatcagaacg tcaagaactc
     1141 aaacaaatag aaagtcgttt gacagagaga gctactagcc ttgaccgtaa ggacgacaat
     1201 ttgacgagta aagaacaaac acttgaacaa aaagaacaaa gtatttctga tagagcgaaa
     1261 aaccttgatg cgcgtgaaga gcaattagag gaagtcgaaa gacaaaaaga agcagaacta
     1321 gagcgtattg gtgctctgtc tcaggcagaa gcacgagata ttatcttggc tcagacagag
     1381 gaaaacttga ccagggagat tgccagtcgc attcgcgaag ctgagcaaga ggtcaaggaa
     1441 cgctctgaca aaatggccaa ggacatcttg gttcaagcta tgcaacgtat cgctggtgaa
     1501 tatgtagcgg agtcaacaaa ctcaacggtt catctgccag acgatactat gaagggacgc
     1561 attattggtc gtgaaggtcg taacattcgt acctttgaaa gtttgacagg ggtcgatgtg
     1621 attatcgacg atacaccaga agtggtgacc ttgtcaggat ttgatccgat tcgtcgtgag
     1681 attgcccgta tgactatgga aatgttgctc aaagatggtc gtatacatcc agctcgtatc
     1741 gaagagttgg ttgagaaaaa ccgtcaagag attgacaata agattcgtga atacggtgag
     1801 gctgctgctt atgaaattgg tgcgccaaac cttcatccag acttgatgaa gattatggga
     1861 cgtttgcagt tccgtacttc atatggacaa aatgttttgc gccattcgat tgaggttgct
     1921 aagttggctg gtatcatggc gagcgaactt ggtgaaaatg cggctcttgc ccgtcgtgct
     1981 ggattccttc acgatatcgg gaaagccatt gaccatgagg ttgaaggtag ccacgttgaa
     2041 atcggtatgg aattggcccg taagtacaag gaacccccag ttgtggtgaa tacgattgct
     2101 agtcaccacg gagatgttga agctgagagc gtgatagcag ttatcgtcgc tgcagcagat
     2161 gccttgagcg cagcccgtcc aggtgctcgt agtgagtctc ttgaaagcta catcaagcgt
     2221 ctccatgatt tggaagaaat tgctaacggc tttgaaggag tgcaaactag ctttgccctt
     2281 caagcaggac gtgaaattcg tatcatggtc aatccaggaa aaatcaagga cgacaaagtc
     2341 acaatcttgg ctcacaaagt tcgtaagaaa attgaaaaca atctcgatta tccaggaaat
     2401 atcaaggtaa ccgtgattcg cgagcttcgt gcagtagatt atgctaaata aataagaaag
     2461 agcagttgaa aaattactgc ttttttgtta cactagatag aaagactgta aaggataatc
     2521 tggctttttg ccattattct agagaaatgt tatttcacag attgactaaa aggagacaca
     2581 atggcagacc gaggcttact aatcgttttt tctggtcctt caggggttgg aaaaggaacg
     2641 gttagaagag agatttttga gagttctgaa aaccaatttc aatactctgt atcgatgacg
     2701 acacgcgcac aacgtcctgg agaagtggac ggtgttgact atttcttccg tactcgtgaa
     2761 gaatttgaag agctgattcg tcaaggacag atgttggaat acgcagaata tgtcggcaac
     2821 tactatggaa ctcctctgac ctatgtcaat gaaaccttgg acaagggaat cgatgttttc
     2881 cttgaaattg aagttcaggg tgctcttcag gtcaagaaaa aggttccaga tgctgtcttt
     2941 atcttcctga caccaccaga tttggatgaa ttgcaagatc gcttggtagg tcgtggaaca
     3001 gatagtgcag aagtgattgc ccaacgaatc gaaaaggcca aggaagaaat tgccctcatg
     3061 cgtgagtatg attatgcgat tgtcaacgat caggtgcccc tagctgctga acgtgtcaaa
     3121 tgtgtgattg aagcagaaca cttctgtgtg gatcgtgtca ttggtcacta tcaggagatg
     3181 ttaccaaaat ctccaactac ccgataaaat ttagaaaata ggtacaagca aatgatgtta
     3241 aaaccctcta ttgatacctt gctcgacaag gttccttcaa aatattcact cgtaatcttg
     3301 gaagcaaaac gtgcccacga attggaagca ggtgccccag caactcaagg tttcaagtct
     3361 gaaaaatcaa ctcttcgcgc tttagaagaa atcgaatcag gaaacgttac aattcaccca
     3421 gatccagaag gaaaacgtga agcagtgcgt cgccgtatcg aagaagaaaa acgccgcaaa
     3481 gaagaagaag aaaagaaaat caaagagcaa attgctaaag aaaaagaaga tggtgaaaaa
     3541 atttaaggtt ggggggactc aatcttattt tttctattgc aagaatgtac tgacaaggag
     3601 gaggtgagaa gatggcccta gctaagatta tcgtagatgt gcccttgatg cagacggacc
     3661 agccctatag ttacaggatt ccggaggaat ttgagggaat gctggaagtt gggatgcggg
     3721 ttcatgtgcc ttttggtaag ggtaatcgcc tgattcaagg gattgttttt ggtttggagt
     3781 cccaatcaga tggagaagag atggagcaag atttaaaaga tattgcagag gtgctggatt
     3841 tttctcctgt tctcacgcca gaacaactct ggctggctga ggagttacgc aaatctgtct
     3901 tctcctacaa aatctctatc ctcaaggcca tgcttccggg atttctgaat tctagctatg
     3961 acaagattct ctatcctctg gaaggcttga gtcaggaaga acgagtgcgc ctgtttggtt
     4021 cagaagattc gctagccttt tcttctctgg atttaggtaa gcaagctgaa atgatgcgtt
     4081 tgactagaaa aggcctgctt ggtctggaat atcaggcagt cgatcaaaag aaggtcaaga
     4141 cccagtcttg gtatgaggtt gaccatgctc aattagaagg tgttgagatt tctacacgtg
     4201 ccaagaaaaa gttggaactg agagattatc tgctgtctca tccagagagc gcttccttgg
     4261 ctagcttgtt agagtcctac tcgcgagagc aagtcaactt ctttgtggat caaggtgctg
     4321 ttaccatagt ccaaaaggaa gttcgacgct cggctgctta ttttgaagga attgaagcaa
     4381 gtagaccttt ggagttaaat ccagaacaaa gacaggcgcg tgatgcggtt gtgagttcta
     4441 ttggcagttc tcaacctccc tttctacttc aagggattac aggaagtggg aagaccgagg
     4501 tttacttgca gattatccaa ggtgccctgg ataagggcaa gacagctatt ttgctggtac
     4561 ctgagatttc cttgactcct cagatgaccg agcgttttat agcacgtttt ggggacaagg
     4621 tagccattct tcactcagga ttatccaatg gcgaaaagta tgatgaatgg cgcaaggtgg
     4681 agcgtggcga tgcccaagtt gttgttggtg ccagatctgc tatctttgct cctctgaaaa
     4741 atctgggtgt catgattatt gatgaagagc atgaagcggc ttataagcag gacagcaatc
     4801 cccgttacca tgccagagag gtagctattt tacgggctca gtataatcaa gcaactctgg
     4861 tacttggatc tgcaacgccg agcttagaga gccgggcacg tgctggcaaa ggcgtctatc
     4921 aacacttacg tctaacccaa cgtgccaatc ctttggctac aatccctgag gttcaagtga
     4981 ttgactttcg agactatatc ggacaaaatg agacgtcaaa ctttacgcct cctttgctag
     5041 aggctatcca agaccgtctg gttaaaaaag agcaggtggt tctcatgctc aatcgccgtg
     5101 gttattctag ctttgtcatg tgtcgggagt gtgggacggt ggatacttgt cccaactgcg
     5161 atatttctct gaccttgcat atggatacca agactatgaa ctgccattat tgtggtttct
     5221 cgaaggatat tcctcaggtc tgtcctaact gtaagagcca cagtattcgt tactatggga
     5281 cgggaactca gaaggcttat gatgagctag cagaactctt tccccaagct cgcattttga
     5341 ggatggatgt ggatacgact cgaaagaaag gcagtcacca agccttgctt gaccagtttg
     5401 ggcgagggga agcggatatt ttacttggta ctcagatgat tgcaaagggt ttggattttc
     5461 ccaatgttac cctagtcgga gttctaaatg cggatacggc cttgaatctg cctgatttcc
     5521 gttcttctga gagaaccttc cagctcttga ctcaggtggc aggtcgagca ggtcgggctg
     5581 aaaaagcagg tcaagtcttg atacagtcct acaattcgca gcactatgct attcgatttg
     5641 ccaaggatca agattacgaa ggcttttatg cctatgaaat gggaatcaga cgacaactcg
     5701 gctatccacc ttactatttc acgattggta ttaccctttc tcacaagaaa gaagaagagg
     5761 ttttcaaacg tgcctatgaa gtcatgaaca ttttgcggtc aggcttgtca gagaccagtc
     5821 ccattctggg gccaacgcca aaaccgattg cccgtaccca caacctctat cattaccaga
     5881 ttttaattaa ataccgttta gaagatgagc tggggccgac cctcaaccag gtcttggcct
     5941 tgactcaaga acgggaaaat agtgagctcc gtctcagcat tgaccatgag ccgcagcaat
     6001 ttttataaga aggagaagat atgacaaaac taatctttat ggggaccccc gacttttcag
     6061 caacagtctt aaaaggactt ttgacagatg accgttacga aattctagcc gttgtgaccc
     6121 agccagaccg tgctgttggt cgtaaaaaag ttatccaaga aaccccagtc aagcaggctg
     6181 ccaaggaagc aggactatct atctaccaac ctgaaaaatt atctggaagt ccagagatgg
     6241 aagaacttat gaagctagga gcagatggaa ttgtgactgc tgcttttggg cagtttctcc
     6301 caagcaaact ccttgatagc atggactttg ctgtcaacgt tcatgcctcc ctccttccta
     6361 gacaccgtgg tggtgcgcct atccattatg ccttgattca aggggatgag gaagctggtg
     6421 tgaccatcat ggaaatggtt aaggaaatgg atgcaggaga tatgatttct cgtcgcagca
     6481 ttccgatcac agatgaggac aatgttggca ccttgtttga aaaattggcg ctagttggtc
     6541 gtgatttgct tttggacact ctgcctgcct atattgctgg tgatatcaaa cctgaaccgc
     6601 aggatacgag tcaggttacc ttctctccaa atataaagcc agaggaagaa aaactggact
     6661 ggaacaaaac caatcgtcaa ctctttaacc aaattcgtgg aatgaacccc tggcctgttg
     6721 cccatacttt ccttaagggc gaccgcttta agatttatga agccctacca gtagaaggtc
     6781 agggaaatcc aggtgagatt ctctctatcg gcaagaaaga attgattgtc gcaacggctg
     6841 aaggggctct atccctcaaa caagtgcagc cagctggtaa gcctaagatg gacattgctt
     6901 ccttcctcaa tggagttgga cgtacattga ctgtaggaga acgatttggt gactaaagta
     6961 gaaacggcta gaagtttagc tctagcagtg ctagaggatg tttttgtgaa tcaagcatat
     7021 tcaaatattg ccttaaataa acacctcaag gggagtcagc tctctgcagc agacaagggc
     7081 ttagtgaccg agctagtcta tggaacggta gcccgtaaac tgactctgga atggtaccta
     7141 tcccacttta tcgaagacag agaccagtta gacagctggc tctatgtcct tcttctcatg
     7201 agtgcctacc aactccgcta tttggacaag attccagatc atgctgtggt caatgaagca
     7261 gtggaattgg ccaaactccg taaaaaaggc agtgaaaaat tggtcaacgc tgtccttcgc
     7321 cgtatcttgc gtgaaggctg gccagatatt gctagcatca agcgaaaaaa caagcgtgac
     7381 tccattgcct attctctccc agtttggcta gttgccaaac tcaaggaaga atacggagag
     7441 gagagagcaa aagccatctt tgaaagcctg ttagtgcgaa acaaagccag tattcgtgta
     7501 acagacctaa gtcgaaaaga ggaaatccaa gccttgttgg aggcgaatga ttccctttta
     7561 gcaaccactg gtctggttaa ggagcagggg cattttgcag ggcataattt gtttgcggat
     7621 ggagccatta ccatccaaga cgagtccagt cagctggttg ctccgacgct tgatttacaa
     7681 ggtgatgagc gagtgcttga tgcctgtgcg gctccaggtg ggaaaacagc ccatatagcc
     7741 tcttatctta cgacaggtca ggttactgct ctggacttgt acgaccacaa gttggattta
     7801 attcaagaaa atgcccaacg tctgggagtt gaagatcggg ttcaaactca aaaattggat
     7861 gccagaaagg tgcatgagtt ttttgaccag gattcctttg ataagatttt ggtggatgct
     7921 ccttgttcag gaatcggtct tttgcgccga aaaccagata tcaaatacaa taaagaaacg
     7981 gcagatttcg cgtccttgca ggaaattcag ttagaaatat taggtagtgt ttgtcaaata
     8041 ctaggcaaag gtggtataat aacttatagc acctgcacta tcgtctcaga ggagaatttt
     8101 caagtcgtta aggccttttt agagagtcat cccgagttcg agcaggtaaa actagaacat
     8161 gaatgtaagg atatcatgaa agacggctgt atcctcatta cacctgaatt gtatggaagt
     8221 gatggattct tcatcagtca atttcgcaag atatcggatt aggaaggaac tgacacatgg
     8281 aaatttcatt attaacagat gttggtcaga aacgaacaaa taaccaagac tatgtcaacc
     8341 actatgtcaa tagagctgga cgtaccatga ttattttagc tgatgggatg ggaggtcatc
     8401 gcgcagggaa tatcgctagt gaaatggcgg tcacagacct gggtgtagct tgggttgata
     8461 cccagattga tacagtcaat gaagtgcgtg aatggttcgc ccattaccta gaaattgaaa
     8521 atcaaaagat tcaccagctt ggtcaggatg aagcttacag aggcatggga actactttgg
     8581 aagtccttgc tattattgat aatcaggcta tctatgctca tattggtgat tcgcgtatcg
     8641 gcttgattcg tggagaagaa taccatcagt tgacgagcga tcattccttg gttaatgaat
     8701 tgctcaaggc tggtcaattg acaccagaag aggcagaagc tcatccgcaa aaaaatatta
     8761 tcacccagtc tattgggcaa aaagatgaaa ttcagcctga ttttgggaca gttatccttg
     8821 agtcaggtga ctatcttttg ctcaatagtg acggcttgac caacatgatt tcaggcagtg
     8881 agattcgtga tattgtaacc agtgatattc ctttagcaga taaaacggag acacttgttc
     8941 gttttgctaa caatgcagga ggtttagaca acattacggt tgcccttgtt tctatgaacg
     9001 aggaggatgc agaatgatcc aaatcggcaa gatttttgcc ggacgctatc ggattgtcaa
     9061 acagattggt cgaggaggca tggcggatgt ctacctagcc aaagacttaa tcttagatgg
     9121 ggaagaagtg gcagtgaagg ttctgaggac caactaccag acggacccga tagctgtagc
     9181 tcgttttcag cgtgaagcga gagctatggc agatctagac catcctcata tcgttcggat
     9241 aacagatatt ggtgaggaag acggtcaaca gtatcttgca atggagtatg ttgctggact
     9301 agacctcaaa cgctatatca aggaacatta tcctctttct aatgaagaag cagtccgtat
     9361 catgggacaa attctcttgg ctatgcgctt ggcccatact cgaggaattg ttcacaggga
     9421 cttgaaacct caaaatatcc ttttgacacc agatgggacg gccaaggtca cagactttgg
     9481 gattgctgta gcctttgcag agacaagtct gacccagact aactcgatgt tgggctcagt
     9541 tcattacttg tcaccagagc aggcgcgtgg ttcgaaggcg actgtgcaga gtgatatcta
     9601 tgccatgggg attattttct atgagatgtt gacaggccat atcccttatg acggggatag
     9661 cgcggtgacc attgccctcc agcatttcca gaaacccctg ccgtccgtta ttgcagaaaa
     9721 tccatctgta cctcaggctt tagaaaatgt tattatcaag gcaactgcta aaaagttgac
     9781 caatcgctac cgctcggttt cagagatgta tgtggacttg tctagtagct tgtcctacaa
     9841 tcgtagaaat gaaagtaagt taatctttga tgaaacgagc aaggcagata ccaagacctt
     9901 gccgaaggtt tctcagagta ccttgacatc tattcctaag gttcaagcgc agacagaaca
     9961 caaatcaatc aaaaacccaa gccaggctgt gacagaggaa acttaccaac cacaagcacc
    10021 gaaaaaacat agatttaaga tgcgttacct gattttgttg gccagccttg tattggtggc
    10081 agcttctctt atttggatac tatccagaac tcctgcaacc attgccattc cagatgtggc
    10141 aggtcagaca gttgcagagg ccaaggcaac gctcaaaaaa gccaattttg agattggtga
    10201 ggagaagaca gaggctagtg aaaaggtgga agaagggcgg attatccgta cagatcctgg
    10261 cgctggaact ggtcgaaaag aaggaacgaa aatcaatctg gttgtctcat caggcaaaca
    10321 atccttccaa attagtaatt atgtcggccg gaaatcttct gatgttatcg cggaattaaa
    10381 agagaaaaaa gttccagata atttgattaa aattgaggaa gaagagtcga atgagagtga
    10441 ggctggaacg gtcttgaagc aaagtctacc agaaggtacg acctatgact tgagcaaggc
    10501 aactcaaatt gttttgacag tagctaaaaa agctacgacg attcaattag ggaactatat
    10561 tggacggaac tctacagaag taatctcaga actcaagcag aagaaggttc ctgagaattt
    10621 gattaagata gaggaagaag agtccagcga aagcgaacca ggaacgatta tgaaacaaag
    10681 tccaggtgcc ggaacgactt atgatgtgag taaacctact caaattgtct tgacagtagc
    10741 taaaaaagtt acaagtgttg ccatgccgag ttacattggt tccagcttgg agtttactaa
    10801 gaacaatttg attcaaattg ttgggattaa ggaagctaat atagaagttg tagaagtgac
    10861 gacagcgcct gcaggtagtg cagaaggcat ggttgttgaa caaagtccta gagcaggtga
    10921 aaaggtagac ctcaataaga ctagagtcaa gatttcaatc tacaaaccta aaacaacttc
    10981 agctactcct taaaagcaga tggataatca aaatgagtaa tcaatctttg tcatgatttc
    11041 atggcaaaga ttttttttga gtccagattt gtgatagaat agagggagtt gataaaagga
    11101 ggaaagcatg gaagaatcaa aagaattaaa tgccgtcatt gatgtgatta tgctagcggg
    11161 gactattctc cttaaaagtg gctcagaaat ccatcgtgta gaagatacca tgattcgaat
    11221 cgcgcattcg caggggattg tggattgcaa tgtccttgcc atgcctgccg ctatcttttt
    11281 ctctattgaa aataccaata tttcgcgcat gaagcgcgtg acctcctctt cttataacat
    11341 cgaaaaagtc tgcgatgtga accagatttc tcgtcagcta gttggggggc agattgactt
    11401 agaaacagcc tttaagcaat tgacggcctt gcaagctcaa ccccttccct atactaagtt
    11461 gcaggtaact ctggctgcga cctttagtgc tcctttcttt tcagttatgt ttagcggaaa
    11521 tatctacgac gcacttgggg caggagtggc gaccttattt ggttttgcct tttccctcta
    11581 tgtggaaaaa tttatccgaa ttccctttgt gacagccttt gctggagcct ttgtctttgg
    11641 gataattgcc caattttggg ctcgctacac aggttttcct tcaacggcag atttgattat
    11701 agctggtgcg gtcatgccgt ttgtaccagg tattgccttg accaatgcgg tccgtgatat
    11761 tatgaccaac cacataaact ctggtatgag taagatgttt gaatccctgc tcattaccct
    11821 cgctttaggg gcaggaactt ctgtcgcctt ggtattgatg aactaatatg acactaacaa
    11881 cctttttatt acaagcagta gcaagttttc ttgccattat cactttttta atcgtactca
    11941 atgtgcaacg gtctatgctc ttacctggag ggattttggg catgactgtc tggctaatct
    12001 atctcttgct caaggaaccg accaatgtca ttgtagctac cttcattgca gccattattg
    12061 gttcttgtgt cagccagatt ttaagtattc tttataagac acctgctgtg gtctttatct
    12121 tggccatttt ggcaccgctg gttccaggtt atctctccta ccgaacaact gccttttttg
    12181 tgacagggga ctataataaa gcactggcaa gtgcgacctt ggttgtcatg ttggctttgg
    12241 taatctctat tggaatggct agtggaacag tgattctcag actgtatcat tatataaaaa
    12301 cacatcgagt atcgtagact ttacagaaat aaaagaattt tctgaaaaat gagataaata
    12361 aattaacaac gctttctata tgtgcgagaa taccgcactt atgaagaaat tgcggctgat
    12421 tttggtatcc acgaaagcaa cttaatccgt cggagccaat gggttgaagt aactcttgtt
    12481 caaagtggtg ttacgatttc aaaaactcat cttagtgctg agaatacggt gattgtggat
    12541 gcaacagagg taaaaataaa tcgtcctaaa aaaatcaact agccaattat tctggtaaaa
    12601 tagaaatgtc attctatgga acctcaagcg attgtcacaa gtcaagggag aattgtttct
    12661 ttggatatcg ctgtgaacta ttgtcatgat atgaagttgt tcaaaatgag tcgcggaaat
    12721 attggacaag ctggtaaaat cttggctgac agtaattatc aagggctcat gaagatatat
    12781 cctcaagcac aaactccacg taaatccagc aaactcaaac cgctaacagt tgaagatcaa
    12841 gcctataacc atgcgctatc caaggagaga agcaaggttg agaacatctt tgccaaagta
    12901 aaaacgttta aaatgttttc aacaacctat tgaaatcatc gtaaacgctt cggattatga
    12961 atgaatttga ttgctggcat tatcaatcat gaactaggat tctagttttg caggaagtct
    13021 actactttcc ttattgtctg taaatctact gaccttgttg tttatcccag tcatggtttc
    13081 tagttcgggc tcagagtttc aaagtggatg gtaagagcat caattgattg ctgagaaggt
    13141 tagtaaaaca cttgacaaga catttgataa ggatgtcaga gaaattccga ccagtcagtt
    13201 ttatcaagaa tttgtagatg agatgggaag gacttactca ggaaatttga tcctccagga
    13261 gctgataact gtgaatgaag cttataaagc tacttatatc ggtgaacttt ctagcaacta
    13321 atcattcttt aaaatgatga ccaataagag gcttgatttg gtgaatcaag tcttttttct
    13381 ctcttttact gccatttgtg ataaaatagt atagaacgat tttttacatg aatgataaaa
    13441 cagaggtaaa tatgacaatc ggtattgata agattggttt tgcgaccagt caatatgtct
    13501 tgaaattaca agacttagca gaagcgaggg gaattgaccc tgaaaaatta agtaaaggac
    13561 tcttactcaa ggaattgagt attgcgcccc taactgagga cattgtgacc ttggcggcca
    13621 gtgctagtga ctctatttta actgagcaag aaagacaaga agttgacatg gtcattgtgg
    13681 ctaccgagtc aggaattgac cagagtaagg ctgcggccgt ctttgtgcat ggcttgctgg
    13741 gcatccagcc ctttgctcgt agtttcgaga ttaaagaagc ctgttatgga gcgactgctg
    13801 cccttcatta tgccaaattg catgtggaaa attctccgga gtccaaggtc ttggtcattg
    13861 ccagtgatat tgccaaatac ggtattgaaa ctccaggaga accaactcaa ggtgctggaa
    13921 gtgtagctat gttgattaca caaaatccac gcatgatggc ctttaataat gacaatgtag
    13981 ctcagacccg tgacatcatg gatttctggc gaccaaatta ctcgacaact ccttatgtaa
    14041 atggtgttta ttctacccaa caatacttgg atagtttgaa aacgacttgg cttgaatatc
    14101 aaaaacgcta ccagcttact ctggatgatt ttgcggctgt ttgtttccac ttgccttatc
    14161 ctaaattagc gctaaaaggc ttgaaaaaaa tcatggataa gagcctgcct caagagaaaa
    14221 aagacctctt acaaaagcat tttgaccagt ctattctcta cagtcaaaag gtggggaata
    14281 tctacacagg ttcacttttc cttggacttt tgtctctctt ggaaaataca gatagcttga
    14341 aagctgggga taaaatcgcc ctttatagtt acggaagtgg agctgtggct gagttcttca
    14401 gtggtgaatt ggttgaagga tatgaagctt atttggataa agaccgcttg aacaagctca
    14461 accaacgaac tgccctatcc gttgcagact atgaaaaggt cttttttgag gaagtaaact
    14521 tggatgaaac aaactctgcc cagtttgctg gctatgaaaa tcaagatttt gccttggttg
    14581 aaattctcga ccaccaacgc cgttatagca aggttgaaaa ataatgaaga taagttggaa
    14641 tggattttct aaaaaatcat accaagagcg cctcgagctg ttaaaagctc aggcgctcct
    14701 tagtcctgag agacaagcta gtctggagaa ggatgaacag atgagcgtga ctgtggcaga
    14761 ccagctgagt gagaatgtag tgggaacttt ttctctgcct tattcactgg ttccggaggt
    14821 acttgtcaac ggtcaggaat acaccgttcc ctatgtgaca gaagaaccct ctgtggttgc
    14881 ggcggccagc tatgccagca aaatcatcaa gcgtgcaggt ggttttactg cacaagtcca
    14941 tcagcgacag atgattgggc aggtagccct ttatcaagtt gctaatccta aactagcgca
    15001 agagaagatt gccggcaaga aagcggagct cttggagctt gccaatcaag cctatccttc
    15061 tatcgttaaa cgtggaggtg gggcgcgtga tctgcatgtc gagcagataa aaggtgaacc
    15121 agactttctc gttgtttata ttcatgtcga tacccaggaa gccatgggtg ccaatatgct
    15181 caacaccatg ctggaagcct tgaaaccagt cttagaagaa ctcagtcagg gacagagtct
    15241 catgggaatc ctgtccaact acgcgaccga ttctctggtg actgcaagct gtcgcatcgc
    15301 ctttcgctac ttgagccgcc aaaaggatca aggacgagag attgcggaga aaattgcgtt
    15361 ggctagtcag tttgcgcagg ctgatcctta ccgagctgct actcataata aaggaatttt
    15421 taatggtatt gatgcgattt tgattgccac tggtaatgac tggcgtgcca tcgaagctgg
    15481 ggcccatgcc tttgccagtc gagatggacg ttatcaaggt cttagttgct ggacgctgga
    15541 ccttgaaaga gaagaattgg tcggtgagat gaccctgccc atgcctgtag cgactaaggg
    15601 tggctctatc ggcctcaacc cacgtgtagc tctcagtcat gatctactag gaaatccttc
    15661 tgccagagaa ttagcccaga ttatcgtgtc catcggtctt gcccaaaatt ttgcagccct
    15721 caaagccttg gtaagtacgg gcatccagca aggccacatg aaactacagg ccaactccct
    15781 agctctccta gctggggcta gtgaatctga agttgctccc ctagtcgagc agcttatcgc
    15841 agataaaacc tttaacctag agacagccca gcgctatctc gaaaatttaa gatcataaaa
    15901 actcagacga atcggtctga gttttcttgt gtttaaatac tttttcctgg taatagcgta
    15961 actggtaaga agtaaccagt tgtggcgact tccttgcctt caatcttttg caagagaaga
    16021 tcaatagtga gacaagcaat ctcttccaaa ggttgcttga tagtagccaa ttgagggtag
    16081 taattttcga taaagtaggt cccatcatag ccgatgacct tgagctcttt tgggacagaa
    16141 attcccaatt cttgagcgat tttaatgacc agaatagctg tcaaatcatc cgaagcaaaa
    16201 atggcatctg gtttttcccg ggtcaagata ttcttgattt ccatttcttt tctgacggga
    16261 gaaaagtcac tggaaacatt gataatagga gcttttggga gtacggatgc aaaaccagcg
    16321 tggcgcagtc cggttggcga attggaattg tcattccctg taatcatgat gatagactgg
    16381 gcacctgtct tgaccaaggt ttgggcagca agaaccccac cagcatagtt gtcagaggag
    16441 acaacaggga tgtctggcga taggtttcgg tcaaaggaaa taatcggcgc tgtcacacga
    16501 ttgtagtctt cgattcctag gttgtgacta ccagaaatga tgccgtctac ctgattggct
    16561 tccaacattt cgatgtattc gcgttccttc tcagaatcat gttcactgtt gcagatgatg
    16621 gtcttgtaac catttttgaa gagttggtgt tccaatttat caatcaattc tgcatagaaa
    16681 acattggaaa tattggggaa aatcaagccg attaacttag ctgattttcc ttgcagacta
    16741 cgagccaggt tgttgggttt atagcccaat tctctcatgg cttcattgac tttttggatg
    16801 gttttctcag atagataccc ttttttattg ataacccgag aaacggtagt aggactgacg
    16861 cctgcaagtt tggcgacatc agttagtttt gcgaccataa tctaattcat agtaaattcc
    16921 agttgggttt ccagatttga tcaggatacc attttggtcc gcatgtggga agacacgacc
    16981 agaaaatact ttttctcctt tattgatgaa aatttcaaag acagagttat cgatgaagat
    17041 tgtagcagta gtagcctgat tctcgatagg gcaagaacga gttgtcccaa attcttgggc
    17101 atactgttct ccagcctggc tacgatccac tgtcacttga ccgtttacaa ggtcaaagtt
    17161 gattgaaagt cccttacctt ctttatcagc aagtaagaca atctcgctct ggctattagc
    17221 ttccaagttg agttcaagtt cgtaagtgtt cttggtttgg gaacggtttg agaaggcttc
    17281 ttcagaagca cgaaggtcct taatagcagc gactggatac tggtagagct tgtcgtcttt
    17341 gatagtgagt tccttgacca aagagaaggt tccttggtgg tcaaaacggt cagatgggta
    17401 agaaacatct ggcaaaccaa gccagctaac tgctagagca cgcccatcag gagcgttgaa
    17461 ggcttgagtt gcataggctt cgaaaccgta atccatgttt tgaagttgag acacatctac
    17521 cattttggca tttttagggt caaaggaagc cccaatctta tacatatttg gaaagatatt
    17581 atcgtagtct agaactttct tatccaatcc ttgtggacag tagagaagga caggttgttc
    17641 ctctacaaag accagattag gacattccat catgtaggca gtacggtcgt tagcaaagtc
    17701 aaggtcgcca actgcttgcc agtttgtgta gtcgttattg acagccttgt agagacgaac
    17761 gaaacctttt ttctccaagt cttgtccgcc gacaatggca taatattgac cctgaaagtt
    17821 aaaaatttgt ggatcgcgga agtggtcagt agagtctgct ggctggtcaa tcaagatctt
    17881 gtcaatcttt gtaatcttac cctccttgtc catcaaagca ccgatctggt atgggtgacg
    17941 gatccagttt ttatcgcgaa catttcctgt ataaaatagg aataagttat cgccaaattg
    18001 catggcagaa ccagagtagg caccgtggct atctaatgga gtatctggta aaactttgat
    18061 tccagtttct ttaaagtgaa tcaaatcatc actttctagc tgtgcccaag attttaaacc
    18121 gtgggctgca ccaaaaggaa aattctggta aaagaggatc cacttgccat caaagtaaga
    18181 aaagccattt gggtcgttga gaagtcctgt ttttggctca acatggtaat gagtatgcca
    18241 tggagattgt gccatatttt cctttatatg ttgaatttct tcttgcgtcc aatcttgata
    18301 aagtctgtaa cgacgctcag ttgtccattc cattcattcc tccaaaaatc ttatcacttt
    18361 taatagtaac tgttttcgat aaaaaatgca agccttttat attaaaaaag agaaaaaact
    18421 gtcaaacgat tatcataaaa taaatacagg aaatcaatca aatttttacg aaaatgtgaa
    18481 agataatgaa ataaaatact ttttaaccaa ggtttcaaac ttatttttca aggaattcct
    18541 gatgaaacag tcaaaaacaa tcaatctaaa gcttgcccac taagtggata gaatattttt
    18601 ttctgcaaaa cgcttgacat atttttaaaa catgataaaa taatagtcgt aagggcgaat
    18661 aaaatcgctt tcaaacaaga acaaaatgtt atataaggag atttttgcaa atgaacaatc
    18721 aggaaattgc aaaaaaagtc atcgatgcct tgggcggacg tgaaaatgtc aatagtgttg
    18781 cccactgtgc gactcgtcta cgtgtcatgg tcaaagatga agagaaaatc aataaagaag
    18841 tgattgggaa cttggaaaaa gttcaaggtg ctttctttaa ctcagggcaa taccaaatta
    18901 tctttggtac aggtacagtt aacaaaatgt acgatgaagt tgttgtactt ggcttaccaa
    18961 catcatctaa ggatgacatg aaagcagaag ttgctaaaca agggaactgg ttccaacgtg
    19021 ctatccgtac tttcggtgat gttttcgttc caatcatccc agttatcgta gcgacaggtc
    19081 tcttcatggg tgtgcgtggt cttttcaacg ctcttgaaat gccacttcca ggtgactttg
    19141 caacttacac acaaatcttg acagatacag ccttcatcat cttgccaggt ttggttgtgt
    19201 ggtcaacctt ccgtgtattt ggtggaaatc ctgccgttgg tatcgttctt ggtatgatgc
    19261 ttgtctctgg ctcacttcca aacgcttggg cagttgctca aggtggtgaa gtaacagcga
    19321 tgaacttctt tggtttcatc cctgttgttg gtttgcaagg ttccgttctt ccagccttca
    19381 tcatcggggt tgtcggagct aaatttgaaa aagctgtccg caaggttgtt ccagatgtca
    19441 ttgacctctt ggtaacacca ttcgtgacac ttttggtcat gtctatcctt ggactctttg
    19501 tcattggacc agttttccac gttgttgaaa actacatcct tattgctaca aaagcgattc
    19561 ttagcatgcc atttggtctt ggtggtttct tgattggtgg ggttcaccaa ttgatcgtcg
    19621 tgtcaggtgt gcaccacatc ttcaacttgc ttgaagtgca attacttgct gctgaccatg
    19681 ctaacccatt caacgctatc atcacagctg ctatgacagc tcaaggtgct gctactgttg
    19741 cggttggtgt taaaacaaaa aatccaaaac tgaaaacact tgctttcccg gctgctcttt
    19801 ctgccttcct aggtattaca gagcctgcta tcttcggggt gaacttgcgc ttccgtaaac
    19861 cattcttcct ttcattgatt gctggtgcaa tcggtggtgg attggcttct atccttggac
    19921 ttgctggtac tggtaatggt atcaccatca tccctggtac aatgctttat gttggtaacg
    19981 gacaacttcc acaatacctt cttatggtag ctgtatcatt tgcccttggt tttgctctta
    20041 cttacatgtt tggttacgaa gatgaagtag acgcaactgc agctgcaaaa caagctgaag
    20101 tggctgaaga aaaagaagaa gttgcgccag cagctcttca aaatgaaaca cttgtaactc
    20161 ctatcgtcgg tgatgttgtc gctcttgctg atgtcaatga cccagtcttc tcaagtggag
    20221 ctatgggaca aggtatcgct gtgaaaccaa gccaaggcgt ggtctatgca ccagctgatg
    20281 ctgaagtttc aattgccttt ccaacagggc acgcttttgg tttgaaaaca agaaatggtg
    20341 ctgaagtttt gattcacgtt ggtattgaca ctgtatctat gaacggtgac ggttttgaag
    20401 caaaagttgc tcaaggtaat aaggtgaaag ctggcgatgt tcttggaaca tttgactcaa
    20461 acaaaatcgc tgcagctgga cttgatgata caacaatggt tatcgttaca aatacagctg
    20521 actacgcttc agtagctcca gtcgcaacag gttcagttgc gaagggggat gctgtgatcg
    20581 aagtgaaaat ctaatcaatc ctctctaatg tgaaaacgaa caaatgacat gtttgttcgt
    20641 ttttattaga tagtaagatt tacagaggaa aatctaaaaa atagagacat ttagactttc
    20701 gaagtatgct ataataaaga aaataaaaac aagaggttta tcatgacaaa attatatgga
    20761 agcttggaag cgggcggtac aaagtttgtc tgtgctgtcg gtgatgaaaa ctttaacgtc
    20821 gtagaaaaaa cacaatttcc aacaacaact ccaatcgaaa caatcgataa aaccattgag
    20881 ttcttctcaa aattcgataa ccttgctggt cttgcagttg gttcatttgg gccgattgat
    20941 attgacaaaa actcaaaaac ttatggcttt atcacgacga ctccaaaacc aaactgggca
    21001 aatgtggact tgcttggtgc ccttcgtcgc gccctaaacg tgccaatgta cttcacaaca
    21061 gacgtaaaca gctctgctta cggtgaagtg gttgcccgta acaatgctgg tggtcgtatc
    21121 gaaaacttgg tttactacac aatcggtaca ggtatcggtg caggcgtcat ccaacgtggt
    21181 gagtttatcg gtggtgtggg tcaccctgaa atgggtcatt attatgttgc tagacaccca
    21241 atggatattg aaaaagagtt taagggtgtt tgtcctttcc ataagggatg tctagaaggt
    21301 tatgcagctg gtccaagttt ggaagctcgt acaggtgtac gtggggaaac tattgaactc
    21361 aacaaccctg tttgggatgt tcaagcctac tatatcgctc aagctgcggt taatgcgaca
    21421 gtgactttcc gcccagacgt gattgtcttt ggtggagggg tcatggctca acaacatatg
    21481 ctggaccgtg tccgtgagaa atttacatct cttcttaatg gttacctacc agtaccagat
    21541 gtgcgtgact atatcgtgac gccagcagtc gcaggaaatg gttctgccac acttgggaac
    21601 tttgttcttg caaaagaagt ttcaaaataa agcacaaaat ccgtttggtt tcccaagcgg
    21661 attttgtggt tgaaaacaat atttttgagc ctttccttaa gtgattacgg acggtagcga
    21721 ctttcttcga aattccatac ctaaactttg agcctagtgt ctcaaagttt ccgaatacct
    21781 gaaaccatta gatttcaggt gtttctatca cggcggaaag gctaggtaag tcctcgcctc
    21841 actatcgaaa aatatgcatg atttccatac caaagtatat ttagtatcaa gctatagtta
    21901 atctacgctt taaaaatcca cttgggaaac caaacggatt ttttacgtgt caaagcattt
    21961 gccagaaaaa gtcaataata taggtcagac cgtaggtata aaccacgagg gtaaagggtt
    22021 tggtcagaat gatgatggtc atgtagcgct tgaaactcat cttggtcagg gcagccagca
    22081 tacagagaaa gtcagctggg ctaatgggcc aaatcatcat aaaaataaag aagcggtcaa
    22141 aacgattgcc cttatctagc cagccgatgt acttgtcgta ggtgcgcttg ctgacgacag
    22201 actggacaaa ggcagctccg tataggcgca ctagataaaa gataatggca cagccaatca
    22261 cgatgccgat atagttgtag atagtcccga tgatgtgccc gtagataaag accccagcca
    22321 ccgaggtcaa ggcccctgga atgataggga cgacagtctg taaaatctgt aaaaagataa
    22381 agagaggtgg accccagatg cctgcctgct ggataaaggc agagagggtt tccttggatt
    22441 gtaaaatccc agcctgataa gcccaaatac agaaaatcaa actcccaacc ccaccgacaa
    22501 tcgatgagat attgataact cgctgcagaa ggggagaaac agctttcatt tgtttatcct
    22561 gtgacatgta aactcctcat agatagtata tttctactat accatatttt ggaggagaaa
    22621 gggggaatga gtcttttttg ataaggaata gaaagtaaat agcccttcga gacttagaat
    22681 aggtctgtca actaaaggtt atatgcattc taggtttcga ataatcgcaa ttacataaat
    22741 ttaaaagcat tctaagtttc gaatagctta tctgagataa ttttgaggca ttcgcgcttt
    22801 cgaatagtca ttttccctaa agtttagatg tattctgaag ttagaaagac taaaatctaa
    22861 aagtagtaag agtctctctc tgatggacgt aatttatggc tagtatgaat cctttgaatt
    22921 gttagttaat tttaatatta atcagttctg aaataattac taaatatagt tagatagtga
    22981 attaattatt gctaaatttc aagttcaagt tagtcatcca gaagtcttct ctgggggact
    23041 tgtagttcaa gcatttttta ggatagttgt taatccgctt ttcgatgaat gcgacttcct
    23101 tggtagtcgt tttcttagtt cccttaggct taggtaacca tttacgaatg aacctgttgt
    23161 gatttttatt agatcctata gtggtgtgca taatagatat aatagattga aactagaata
    23221 gtacacatct acttctaaaa cattgttaga aatcgatttg actgtcccga tctatttgtc
    23281 ctgtttttat ttcattttat tatataatcc ttagaaaaca tatcggacaa gcggttgaat
    23341 tctgttccgt ccattagtag ataaaggatt actccttctt gaaatgacag atgaacttgt
    23401 ttcttataaa aatgttgtct gaaactattc gcttttttcc agaaatttta gaggaagaaa
    23461 actttatgag gaaaaaggag ttactcaaat aacaattcag gattaaaaat agacagttga
    23521 ggagcggaag gtataaatta agtttgctac tgtataatgg atttatcact aatactcttc
    23581 gaaaatctct tcaaaccacg tcagcttcgc cttgccgtag atatagttac tgacttcgtc
    23641 agttctatcc acaacctcaa aacagtgttt tgagctgact tcgtcagttt tatctgcaac
    23701 ctcaaagctg tactttgagc agcctacggc tagcttccta gtttgctctt tgcttttcat
    23761 tgagtataaa agtgctccag gccatatttt acacagcaat agtcttctaa aaatggacaa
    23821 aaacattgta aaggctatca aaaaggagta taatgagtgc aagaaatttc ggaggtgaaa
    23881 gatgctagaa gtaagaagtc tagagaaaag ttttggctcc aagcaagttt tgtttggtat
    23941 tgactttcaa gcgcgaccag gtcgtatttt gggactagtc ggaaaaaatg gtgctggaaa
    24001 aacaacgatt ttccatagta ttttgaaatt cctagaatat cagggagaaa tcggtctgga
    24061 tggtcaggat attcgtcagg agacctatgc tcggattggt tatctgcctg aagaacgcag
    24121 tctcatgcct aaattgacag ttcttgaaca agttcgctac ttggcgactc taaaaggcat
    24181 ggatgccaaa gaagtcaaag aaaaactccc tcaatggatg aagaggttgg aagtgaaagg
    24241 aaagctgaca gataaaatca agagtctgtc aaaaggaaat cagcagaaga ttcagctcat
    24301 tattactctg attcatgaac cagacctgat tatcttggat gagcctttta gtggattgga
    24361 cccagttaat acagaattgc tcaaacaagt catttttcag gaaaaagagc gcggagcaac
    24421 cattatcttt tctgaccatg tcatgaccaa tgttgaggaa ctttgtgacg atattctgat
    24481 gatccgagat ggccgtgtgg tcttgcacgg accagttcag gatgtccgca atcaatacgg
    24541 gaaaacgcgt ctctttgttt caagtgaacg aagcaaggaa gaattggaaa atcttcctca
    24601 tgtcaaacag gtgagcttga ccaaacaagg cagttggaaa ttgattttgg aggatgagag
    24661 cgctggaagg gaactcttcc caatcttgac tcaaggtcaa tatatcgcaa catttgacca
    24721 acaagcgcca actatcgatg aaatctttaa actagaatca ggagtggaag tatgagaaat
    24781 atgtgggttg taatcaagga aacctatctt cgacatgtcg agtcatggag tttcttcttt
    24841 atggtgattt cgccgttcct ctttttagga atctctgtag gaattgggca tctccaaggt
    24901 tcttctatga ctaaaaataa taaagtggca gtagtgacaa cagtgccatc tgtagcagaa
    24961 ggactgaaga atgtaaatgg tgttaacttc gactataaag atgaagcaag tgccaaagaa
    25021 gcaattaaag aagaaaaatt aaaaggttat ttgaccattg atcaagaaga tagtgttcta
    25081 aaggcagttt atcatggcga aacatcgctt gaaaatggaa ttaaatttga ggttacaggt
    25141 acactcaatg aactgcaaaa tcagcttaat cgttcaactg cttccttgtc tcaagagcag
    25201 gaaaaacgct tagcgcagac aattcaattc acagaaaaga ttgatgaagc caaggaaaat
    25261 aaaaagttta ttcaaacaat tgcagcaggt gccttaggat tctttcttta tatgattctg
    25321 attacctatg cgggtgtaac agctcaggaa gttgccagtg aaaaaggcac caaaattatg
    25381 gaagtcgtct tttctagcat aagggcaagt cactatttct atgcgcggat gatggctctg
    25441 tttctagtga ttttaacgca tattgggatc tatgttgtag gtggtctggc tgccgttttg
    25501 ctctttaaag atttgccatt cttggctcag tctggtattt tggatcactt gggagatgct
    25561 atctcactga ataccttgct ctttattttg atcagtcttt tcatgtacgt agtcttggca
    25621 gccttcctag gatctatggt ttctcgtcct gaggactcag ggaaagcctt gtcgcctttg
    25681 atgattttga ttatgggtgg tttttttgga gtgacagctc taggtgcagc tggtgacaat
    25741 ctcctcttga agattggttc ttatattccc tttatttcga ccttctttat gccgtttcga
    25801 acgattaatg gctatgcgga gggagcggaa gcatggattt cacttgctat tacagtgatt
    25861 tttgcggtgg tagcaacagg atttatcgga cgcatgtatg ctagtctcgt tcttcaaacg
    25921 gatgatttag ggatttggaa aacctttaaa cgtgccttat cttataaata gaagagcctt
    25981 gcgaaagcga ggtttttaaa ggtgaaaagg gtggaatcac gaacctaatt atgtacacat
    26041 tatgtaaaca ggttgcttga aaactcaatt gtatagtgaa ctgaatctgg aataggataa
    26101 tattacttct aaaacattct tataaattga tttgaattcc aaaatcccat cgttccgttc
    26161 ttatttcatt ttgcgatata gcgaaaggaa ataagtcagc tcacaaaaaa cgcataatat
    26221 caaggatttt taacacttga tactatgcgt tttctaattt taaagacttt ttgcctggtc
    26281 tcttttgttc tatgagtatg ttacatatct aggtaaaaat tatttaaagc aaattaacct
    26341 tatttctcaa gatgtagtag gttccgagat aaaagatagc tatgaatatg agttctttaa
    26401 caatggctat acctgctccc atatagaaat ggtcattgag tcctaccagt gaattgacat
    26461 agaaattaga actaagattg aagaaaagtt caataaatcc aatgacgatt tggataccaa
    26521 tgtaggctgc aacagcgagt gctgtacggt attcattgaa aagctgtcca atggaaatag
    26581 ccaggtagat gcagaggatt cctgaaatgg tatttagtag gaaggatata cctgtaagaa
    26641 agatctgagg gagatgtgtt tctacaaatg taatcacata agaaagagga atccattctg
    26701 gagctgttaa agccagaata ataacagcac ttagagccaa tacagcggtg ctaatcaatg
    26761 accagataaa ggcaccgatt agtttggctg tgatgatatg gtgttcagaa actggcaagg
    26821 tcaaagtcag atagccttgt cggtcgtaga cactaccttt gaagcgttta ataatcaaga
    26881 aaatggttga aatcgcaagt gtaagcatca agccaccaaa gactgtagct agaaaaagta
    26941 gcatagtagc ctgactttct tggtaaggta gatttttaaa gccttgtgtc tgtattccga
    27001 tgagggcaga aaggactagc acggctgcgt agagggctaa ataccacttg ttaacatttt
    27061 taaattcgta gtgaactaaa ttccaaaaca taaataatct cctttgctta ggccttaaat
    27121 tcctgacgga agagttggtc aatggattca cctgactcgt agcgaatatc atctacattt
    27181 ccttgacgga cgacttttcc gtcttttagg aagacaattt catccaagat tggctcgata
    27241 tcagaaatca agtgggtaga aatcaaaacg gtagaagttg gtgagtagtt gttgataatg
    27301 gtattgagga tataagcacg ggctgctgga tccaccccac caatgggttc atccaaaaca
    27361 tagagacgag catcacggct cataaccaaa atcagttgaa ccttttcttt gtttcctttt
    27421 gatagtttct tgagacgact attttcatca atgcccaggt ctgcaagtag atgatgagcg
    27481 cgttcaagat tgaaatcttt atagaaggtc ttgaagtagg ttagggcttc tttgaccttc
    27541 atttgctcat tgagataggt cgtatcaggc aaataagcta caacggcctt ggttgctggg
    27601 cttgggtcca tgtcgttgat gaggacacgt ccttgatctg gttgtaagag gccattaatt
    27661 agtttaatca gggttgtttt tcctgagccg tttggcccaa gaaggccgac aatttttcca
    27721 gctggaatgt caagagaaac attttcaagg gctggtgttg ctccatatga tttggataca
    27781 ttttcaaatg ctagtaatga cataggctta aactccttta atataatcac tgactacgcc
    27841 tggtagttct tctttttcat agccaaaatg ggtcatggag gaaacgaagt gttccaattc
    27901 ttcttctgat aattgtttgc gtgactgagc gattagctcc ttatccttag tcacaaatcg
    27961 tccagttgtt cgcttgctgt agacaaatcc ttctcgttca aggtctgata aggctctttg
    28021 gatggtattg ggattgacac cagcctcgct agctagctcc ctcacggttg gaagttgttg
    28081 attgggttcc agtgtatggg aaacaatctg aagcttgatt ttctccataa tctgtaaata
    28141 gatgggtttt ttgttgtcaa atgtccagga catcttagtc tcctttctct tattcttttg
    28201 tcttaattaa ataatacaac aaaacaaaaa acttgtcaag caaaaagaag aattgttttg
    28261 ggaatcgctt aaaaaatggt ataatgaaaa gaaaacgata aggagggaaa ggatgcgttg
    28321 tccaaaatgt ggggctacca agtcaagtgt tatcgatagt cgccaagcag aagaagggaa
    28381 caccattcgt agaagacgag agtgcgacga gtgccaacac cgttttacaa cctacgaacg
    28441 agtagaagaa agaaccttag tggttgttaa aaaagatggc acacgggaac aattctccag
    28501 agataaaatc tttaatggga ttatccgctc agcccagaaa cgtcctgtgt caagtgatga
    28561 aatcaacatg gtagtcaatc gtatcgaaca gaaactccgt ggtcgaaatg aaaatgaaat
    28621 tcaaagtgag gacattggtt cactcgtcat ggaggagttg gctgaattgg acgagattac
    28681 ctatgtacgt tttgctagtg tctatcgtag ttttaaggat gtcagtgagt tagagagctt
    28741 gctccaacaa atcacccagt cctctaaaaa gaaaaaggaa agataaatga agccaattga
    28801 ccgtttttct tatctaaaga ataatcgggt gtcgcaagat acctcatctc tggtacagtg
    28861 ctacctcccg attatcggtc aggaggcact gagcctttat ctttatacaa tcagtttttg
    28921 ggataatggt agaaaggaat atcttttttc aagtatcctc aatcatctca actttgggat
    28981 ggatagactg ataaaatcat tgaaaatctt atctgctttt aatctcttga ccctctatca
    29041 aaagggggat gtttatcagc tagccctcca tgctcctcta tctagtcaag acttcttgga
    29101 gcatcctgtt tatcgcagac tcttagagaa aaagattggc gactctgctg tggaggattt
    29161 gaaagttgaa agtgctgatg gtgaagaaat acctgtctca ctcaatcaag tctttccaga
    29221 attggcagaa ctaggcagtc aagaagacct tggtctcaag aagaaagtgg ccaatgattt
    29281 tgacttggaa cattttcgcc agctgatggc tcgagatgga cttcgttttg cggatgagca
    29341 gtccgatgtc ttaaacctct ttgctattgc cgaggagaag aaatggactt ggtttgaaac
    29401 ctatcaattg gccaagtcaa cagctgtttc tcaggttatt tcaaccaaac gcatgcgtga
    29461 aaaaattgct caaaaaccag tttcctctga ctttagtctt aaggaaacaa ccattatcaa
    29521 agaagccaaa agtaaaactg ccctgcagtt cttggcagaa atcaagcaaa cacgcaaggg
    29581 aaccattacc caaacagaaa gagaactctt gcaacagatg gctggcttgg gcttgctgga
    29641 cgaagtcatc aatatcattc ttttattgac ctttaataag gtcgattcgg caaatatcaa
    29701 tgagaaatat gccatgaagg tagccaatga ctatgcctat caaaagattc attcggcaga
    29761 aaaggcagtc ttgcgcatcc gtgagcgagg acagaaagca aaaacacaaa aacagaatca
    29821 gactgcccca gtaaaaacca atgttcctaa atggagtaat cctgaatata agaatgaaac
    29881 cagcgaggaa actcgtctgg aactagaacg taagaagcaa gaactattag ctcgattaga
    29941 aaaaggagga gattagatgg aaagtgtcgg agacgtactc aaacgtcaac ccagccgttt
    30001 ttattatcaa gatttggtcc agaaaatcat gaaggaccct gatgttgcgg cttttatcca
    30061 gcaagaatcc ttgactccag aggaattaaa tcgcagtatc tccaagttta atcagtacat
    30121 caccgagcgt gacaagtttc tccgtgggga tacggattat attgccaaag gctacaagcc
    30181 gattttggtt aagaatcatg gctatgcaga tgtttcatat gaagaaactc ctgagctaat
    30241 cgcggctgaa aaagaagcgg ctattaagaa ccgtctcaag ttaatcaatc taccagccag
    30301 tctcaagaaa gctagtttgg ctcaagttga cttggatgat ttggggcgct taccagtttt
    30361 tgaaaagcta ctagccttcg tggagcaata tccagctatt cgaaaaggtc tttacttata
    30421 tggagacttt ggtgtgggta aaagtttcat ggtggcggcc ttagctcatg atttatcaga
    30481 aaaacgtggt gtttcatcaa ctctcctcca ctatcctagc tttgtcattg atgtcaaaaa
    30541 tgctatcagt gatggcaatg ttaagacctt ggtggatgag attaagtttt ctgaagtcct
    30601 gattttagat gatattggtg ccgagcaatc caccgcttgg gtgcgtgatg aaatcctgca
    30661 ggtcattctc caatatcgga tgcaggaaaa tttaccgacc tttttcacct ctaacttcaa
    30721 ctttgaagat ttggagaagc atttcgctaa agggaaaaat ggaaatgacg aaacctggga
    30781 agccagacgt gtcatggaac gcatccgtta tttggctgag gagactcgtt tagaaggagt
    30841 aaaccgtcga tgacagaaac cattaaattg atgaaggctc atacttcagt gcgcaggttt
    30901 aaagagcaag aaattcccca agtagactta aatgagattt tgacagcagc ccagatggca
    30961 tcatcttgga agaatttcca atcctactct gtgattgtgg tacgaagtca agagaagaaa
    31021 gatgccttgt atgaattggt acctcaagaa gccattcgcc agtctgctgt tttccttctc
    31081 tttgtcggag atttgaaccg agcagaaaag ggagcccgac ttcataccga caccttccaa
    31141 ccccaaggtg tggaaggtct cttgattagt tcggtcgatg cagctcttgc tggacaaaac
    31201 gccttgttgg cagctgaaag cttgggctat ggtggtgtga ttatcggttt ggttcgatac
    31261 aagtctgaag aagtggcaga gctctttaac ctacctgact acacctattc tgtctttggg
    31321 atggcactgg gtgtgccaaa tcaacatcat gatatgaaac cgagactgcc actagagaat
    31381 gttgtctttg aggaagaata ccaagaacag tcaactgagg caatccaagc ttatgaccgt
    31441 gttcaggctg actatgctgg ggcgcgtgcg accacaagct ggagtcagcg tctagcagaa
    31501 cagtttggtc aagctgaacc aagctcaact agaaaaaatc ttgaacagaa gaaattattg
    31561 tagaaagtga gaaattatgg ccctaccaac tattgccatt gtaggacgtc ccaatgttgg
    31621 gaaatcaacc ctatttaatc ggatcgctgg tgagcgaatc tccattgtag aagatgtcga
    31681 aggagtgaca cgtgaccgta tttatgcaac gggtgagtgg ctcaatcgtt cttttagcat
    31741 gattgataca ggaggaattg atgatgtcga tgctcctttc atggaacaaa tcaagcacca
    31801 ggcagaaatt gccatggaag aagcagatgt tatcgttttt gtcgtgtctg gtaaggaagg
    31861 aattactgat gcagacgaat acgtagctcg taagctttat aagacccaca aaccagttat
    31921 cctcgcagtc aacaaggtgg acaaccctga gatgcgaaat gatatctatg atttctatgc
    31981 cctcggtttg ggtgaaccac tgcctatctc atctgtccat ggtatcggta caggggatgt
    32041 actagatgcg attgtggaaa accttccaaa tgaatatgaa gaagaaaatc cagatgtcat
    32101 taagtttagc ttgattggtc gtcctaacgt tggaaaatca agcttgatta atgctatctt
    32161 gggagaagac cgtgtcattg ccagtcctgt tgctggaaca actcgtgacg ctattgatac
    32221 ccactttaca gatacagatg gtcaagagtt taccatgatt gatacggctg gtatgcgtaa
    32281 gtctggtaag gtttatgaaa atactgagaa gtactctgtc atgcgtgcca tgcgtgctat
    32341 tgaccgttca gatgtggtct taatggtcat caatgcggaa gaggggattc gtgaatacga
    32401 caaacgtatc gctggatttg ctcatgaagc tggtaaaggg atgattatcg tggtcaacaa
    32461 gtgggatacg cttgaaaaag ataaccacac tatgaaaaac tgggaagaag atatccgtga
    32521 gcagttccaa tacctgcctt acgcaccgat tatctttgta tcagctttaa ccaagcaacg
    32581 tctccacaaa cttcctgaga tgattaagca aatcagcgaa agtcaaaata cacgtattcc
    32641 atcagctgtc ttgaacgatg tcatcatgga tgccattgcc atcaacccaa caccgacaga
    32701 caaaggaaaa cgtctcaaga ttttctatgc gacccaagtg gcaaccaaac caccaacctt
    32761 tgtcatcttt gtcaatgaag aagaactcat gcacttttct tacctgcgtt tcttggaaaa
    32821 tcaaatccgc aaggcctttg tttttgaggg aacaccgatt catctcatcg caagaaaacg
    32881 cagataaaaa agtagaatct ggaatgacag ttccggattt ttttgatata ataaaataat
    32941 agaaaacgct atcaaaagaa ggagggtgat gtcggtgatg gaacatttgt ttaaattctt
    33001 acttttagca ccgtactttt attttgataa ctggattgag aaggccaaca gaaatagtaa
    33061 gttttttcca attttttatt atttttactg gttttacatc cccttctatt ctctttttag
    33121 ccttgcttgg acagttgttt cagttctgtt tttcaatacc gtcttgagaa atgtgacaga
    33181 tatcaagtta tggggcattt ggtttctttt tattctgcta gctattggta tgaattggtt
    33241 aacttattcc tgtttcaaag aaatgtttcg cttgagacag gaactaggga agtctaaggg
    33301 tggaaggcat tgatttatat cggtttctat ttgtaggagg tggcttatgg tacctctaaa
    33361 atcatttatt acacgctatt ccaaggttta tattggtaat aacatttaat agaacgaaac
    33421 taaagaaaac aatttaaaaa aggaggcttg tgatggaaca cttgtttaaa atgataatct
    33481 tattaccctg tttttacttt ttcagctgga ttgacaagga taatagagaa agtaaatttt
    33541 tcccaatttt ttactatttt tactggattt acatcaccct ctattctctt tttagccttg
    33601 cttggacagt tttttcagtt ctgtttttca atatcgtctt gagaaatttg acagatatca
    33661 agttatgggg tatttggcta ttattactac ttatcgcttt tgctagtgac tggttagact
    33721 atatctgttt caaaaaaatg cttgacttga gacgggaact agggaagtct aaaggcggaa
    33781 ggcattgatt tatactcttc gaaaatctct tcaaaccacg tcaacgtcgc cttggattat
    33841 atatgtaact gacttcgtca gtcttatcta caacctcaaa gcagtgcttt gagcaacttg
    33901 cggctagttt cctagtttgc tctttgattt tcattgagta ttatattact ttctatttgt
    33961 aggaggtggc ttatgaagat tcctctctta actttggcaa ggcataaatt tgtttatgtc
    34021 ttgcttactt tgctttttct tgctttggtt tatcgtgatg ttttgatgac ttatttcttt
    34081 tttgatattc atgcgcccga tctagctaaa ttcgatggac aagcaattaa aaatgactta
    34141 ttaaaatcag cattagattt tcgtattctc cagttcaatc taggttttta tcaatcattt
    34201 attattccaa tcatcattgt tttgctaggt tttcaatata ttgagctgaa aaataaagtt
    34261 ttacgattga gtattggaag agaagtgagt tatcaagggt taaaaagaaa gttgactttg
    34321 caagttgcaa gtatcccttg tttgatatat ttagtgactg tgctgataat tgcaattgta
    34381 acctatttct ttgggacttt ttctcctctt ggatggaatt ctctattttc tgatgggagt
    34441 agtttacaaa ggctcctaga tggagagata acaagctatt tgttctttac ttgtgtccta
    34501 ctaatcggta ttttcatcaa tgcagtctat ttttttaaaa tagttgatta tttaggaaat
    34561 gtgactcgtt cggcaatcac ctatttgatg tttctttggc ttggttctat gctgctctat
    34621 agtgccttgc cttactatat ggttcctatg acgagtttga tgcaagctag ctatggggat
    34681 gtaagtttga tgaaactctt tactccttat atcctttata ttgtccctta catggtgctt
    34741 gaaaaatatg aagataatgt ttaagaattt taacaatatt ttgctaaaga gaaagattgt
    34801 tttactactt cgtatagttc tgatgatgat tttgataaac catctattgt caacagcggt
    34861 tcaaaagcag gatgctgtta tctttttcaa gagagaattg atttcaattt tttcctataa
    34921 tgactattct gaagtgaatt tagaaatccc caaactcttg ttaaaccttt cgcttttcat
    34981 ggtaggatgg ctctctgtca ttttacttga aagtgatttg gcagaccatt accatcactt
    35041 gattcgctat caatcaagct cctttttcga ttatacaagg aaacgattgg ttgtcatttc
    35101 taaatttttt actcaagatt tacttgtctg gttccttggt ttacttccgc taggaattca
    35161 tttcaaaaca gtcgcacttt tctttttact tgctcagtta atgatgttgt acttactact
    35221 gtcttatctg atagcactga ttagtgcggg cgctggtttt tccttttttc tctatttttt
    35281 agcatttgtg ggacaagaat ggatgatgga tcatattgta acagtgtatt tactactctt
    35341 aagcttatta gttatgttga ttgttagtcg cttggaagag aaatttaaga aaggataaac
    35401 gatgaaactt gaaattataa atggacagaa aatttatggg aaaagaccta ttttaaatca
    35461 gttgaatttg gtgtttcaat caggaaaaat ttatggactt aaaggtgata atggatctgg
    35521 caagacggtt cttttaaagg tacttgctgg ttatattaag cttgacaaag gaaaagttct
    35581 tcaagatggt aaagtttacg ggataaaaaa tcattatatt caggatgcag gaattttaat
    35641 tgaaaaagtc gagtttttat ctcatttatc cctgagagaa aatttggaac tgttaaggta
    35701 tttttcatct aaagttacgg aaaaaagaat tgcctattgg attcaatact atgatttaca
    35761 ggaatttgaa gacgttgaat accggcattt atccttggga acaaagcaaa aaatggcctt
    35821 gattcaagcc tttatttcct ctccttctat actctttctc gatgaaccta tgaatgcttt
    35881 ggatgagaag agtgtgaggt taaccaaaca ggtcatttta tcttacctga aaaaagaaaa
    35941 tggtctggtt atcctgacgt cgcacatatc ggaagatatt tcagaccttt gtacagatgt
    36001 attagttgtc gaaaatggac atatacaata tgtaaaggat atacaatcct aggagatggc
    36061 ttatggcaca tctaaaatca tttattacac gctattccaa ggtttatatt ggtttagttc
    36121 tgttgatctg gattgctttc ttctttcttc cttggggcag tccgattctg ggggggaaga
    36181 ttgacctctt cagcatacag aaagtcttgc tagtttttgg cattctgtcc attttgatgg
    36241 ccttgctgtc caagaaagtc agtctctttg tttttggatt gatctgctgt ctttctcttt
    36301 ggattaactt atttatccta tttgctattt tgccgattct tggcaattaa agtatcataa
    36361 aagtcagaga ggttagcttg gaaactaacc tctttttcct tttcaaaatg gggattcttc
    36421 cttgaaaata atcagtaatt gtgctaaaat taaaggaaca ttctaaaata ttcggaattt
    36481 aaagtaagga aaaacatggc taatatttta aaaacaatta tcgaaaatga taaaggagaa
    36541 atccgtcgtc tggaaaagat ggctgacaag gttttcaaat acgaagacca aatggctgct
    36601 ttgactgacg accaactaaa agcaaaaaca gttgaattta aggaacgtta tcaaaatgga
    36661 gaatcactgg attcattgct ttacgaagca tttgcggttg tccgtgaagg tgccaaacgt
    36721 gtcctaggtc tcttccctta taaggttcag gtcatggggg ggattgttct tcaccatggt
    36781 gacgtgccag agatgcgtac aggggaaggg aaaaccttga ctgcgaccat gccggtatac
    36841 ctcaatgccc tttcaggtaa aggggttcac gtagttacgg ttaatgaata cctgtcagaa
    36901 cgtgacgcga ctgagatggg tgaattgtac tcttggcttg gtttgtcagt agggattaac
    36961 ttggctacca aatctccaat ggagaaaaaa gaagcctatg agtgtgatat tacttactca
    37021 actaactcag aaatcggatt tgactacctt cgtgacaaca tggtcgttcg cgctgaaaac
    37081 atggtacaac gtccgcttaa ctatgccttg gtcgatgagg ttgactctat cttgattgac
    37141 gaggctcgta cacctttgat tgtatcaggt gccaatgcgg ttgaaaccag tcagttgtat
    37201 cacatggcag accactatgt aaaatctttg aacaaagatg actacatcat cgatgtgcag
    37261 tctaagacta ttggtttgtc tgattcaggg attgacaggg ctgaaagcta cttcaaactt
    37321 gaaaacctct atgacatcga aaacgtggct ttgacccact ttatcgataa cgcccttcgt
    37381 gccaactaca tcatgcttct cgatattgac tatgtggtga gcgaagagca agaaatcttg
    37441 attgtcgacc aatttacagg tcgtaccatg gaaggtcgtc gttattctga tggattgcac
    37501 caagctattg aagccaaaga aggtgtgcca atccaggatg aaaccaagac atctgcctca
    37561 atcacgtacc aaaacctttt ccgtatgtac aagaaattgt ctggtatgac gggtacaggt
    37621 aagactgagg aagaagaatt ccgtgaaatc tacaacattc gtgttattcc aatcccaaca
    37681 aaccgtcctg ttcaacgtat tgaccactca gaccttcttt atgcaagtat cgaatctaag
    37741 tttaaagcgg ttgtcgaaga cgttaaggct cgttaccaaa agggtcaacc tgtcttggtt
    37801 ggtacagtag cggttgaaac tagtgactac atttctaaga aattggttgc agctggtgtt
    37861 cctcacgaag tcttgaatgc caaaaaccac tatagagaag cccaaatcat catgaatgct
    37921 ggtcaacgtg gtgccgttac catcgcaacc aacatggcgg gtcgtggtac cgacatcaag
    37981 cttggtgaag gtgttcgtga acttggagga ctttgtgtta ttggtacaga acgtcatgaa
    38041 agtcgtcgta tcgataacca gcttcgtgga cgttcaggtc gtcaaggaga tccaggtgag
    38101 tcacaattct acctatctct tgaagatgat ttgatgaaac gttttggttc tgaacgcttg
    38161 aagggaatct ttgaacgtct caacatgtct gaagaggcga ttgagtctcg catgttgacg
    38221 cgtcaggttg aagcagctca gaaacgtgtc gaaggaaata actacgatac ccgtaaacaa
    38281 gtccttcaat acgacgatgt catgcgtgaa caacgtgaga ttatctatac tcaacgttat
    38341 gatgtcatta ctgcagaccg tgacttggca cctgaaattc aggcaatgat caaacgcacg
    38401 attggtcgtg tcgttgacgg tcatgcgcgt gctaaacaag atgagaaact agaggcaatt
    38461 ttgaacttcg ctaagtataa cttgcttcct gaagattcta ttacgatgga agacttgtca
    38521 ggcttgtctg ataaggccat caaggaagag cttttccaac gtgccttgaa ggtttacgat
    38581 agtcaggttt caaaactacg cgatgaagaa gcagttaaag aattccaaaa agttttgatt
    38641 ctacgagtgg tggataacaa gtggacagat catatcgatg cccttgatca attgcgtaac
    38701 gcggttggac ttcgtggcta tgctcagaac aaccctgttg ttgagtatca ggcagaaggt
    38761 ttccgtatgt ttaatgatat gattggttcg attgagtttg atgtgacacg cttgatgatg
    38821 aaagcacaaa ttcatgaaca agaaagacca caggcagaac gtcatatcag tacaacagcg
    38881 actcgcaata tcgctgctca ccaagcaagt atgccagaag atttggattt gagccagatt
    38941 ggacgcaatg aactttgccc atgtggttct ggtaagaaat ttaaaaactg tcacggtaaa
    39001 agacaataaa atgagatagt ttagaggcgg atatcttgtg aaaagtaaat ttttactggg
    39061 tatccgtttg ctttataagg agatgagtta tggtatttac agcaaaaagc tctaaaataa
    39121 atatagaaga agttcgtgcc ttgtcaaaat tagaaggtca ggctttggag aggaaatcac
    39181 agcgagatca agagctagaa gccattatac gtggagaaga ccagcgaatt ctcttggtaa
    39241 tcgggccatg ctcatctgac aacgaagaag ctgtccttga atacgctaag cgtttggcag
    39301 tcctacaaga agaagtggca gatcgtatct ttatggttat gcgtgtttat actgccaaac
    39361 cccgtaccaa cggagatggc tataagggct tgattcacca gcctaacgcg acagaagcgc
    39421 ctagtcttat caatggaatc aaagccgttc gccatcttca ctatcgtgtc atcacagaaa
    39481 cagggatgac aactgctgat gaaatgcttt atcctgaaaa ccttccgctt gtagatgatt
    39541 tgatttctta catggcagtt ggtgcccgtt cagttgaaga ccagcaacac cgctttgtgg
    39601 caagtggggc aggattttct actggtttta aaaatccaac ctctggaaat ctcaatgtca
    39661 tgtttaatgg gatttatgct gctcaaaaca aacaaagttt ccttttctta ggaaaagaag
    39721 tagaaacaac tgggaacccg ctttcacacg ctattcttcg tggtgctctt aatgagtatg
    39781 gaaaaaatat tcccaactac tattatgaca atttaattga taccattgcc cagtatgaga
    39841 aaatgggctt ggaaaatcct tttatcatca ttgataccaa tcatgacaat tctggtaagc
    39901 agtatattga acagatccga attgtccgcc agaccttgat taaccgtgct tggaatgaaa
    39961 aaattaagca gttcgttcgt ggttttatga ttgagtctta tctggaagat ggtcgacaaa
    40021 atgagccaga agtatttggt aagtctatca cagacccttg cctgggttgg gataacacag
    40081 aagctcttgt cagagaaatt tacaaaacgt taggagaata agatggcatt tattgaaaaa
    40141 ggtcaagaaa tcgatatgga agtcatcaag gctgaaaccc aattgtctgc ggaagccttg
    40201 agactcaagg aaagccgtga cagggaattg gcagatatta tttcagggga agatgaccgt
    40261 attctcttgg tgattggtcc ttgctcttct gataatgaag aggcggtctt ggaatatgct
    40321 cgccgtttat ctgccttgca aaagaaggta gcggataaga ttttcatggt catgcgcgtg
    40381 tatactgcta agcctcgtac caatggagac ggctataaag gattagttca ccagccagat
    40441 acttctaagg ctccaagcct gattaatggc ttgcaggctg tgcgccagtt gcactaccgc
    40501 gtgattacag agactggttt gacaacggca gatgagatgc tttatccgtc aaatctgatc
    40561 ttggtggatg acttggtcag ctaccatgcc gttggagctc gttctgtgga agaccaagag
    40621 caccgctttg tggcttctgg gattgatgca ccagtaggga tgaaaaatcc aacctcagga
    40681 aatttgggtg ttatgtttaa cgccatctat gctgctcaaa acaagcaaac cttcctttat
    40741 catgggcagg aagttgagac atcaggtaat cctttggccc atgttatcct ccgtggagca
    40801 gtcaacgagt atggcaatta tatgccgaat tactactatg aaaatctact ccaagccatt
    40861 gaacgctatg aaaccatggg acttgaaaat ccttttatcc tcattgacac caaccatgat
    40921 aactcaggca agcaatatat ggagcagatt cgaattgttc gccagacctt gcagaatcgt
    40981 gattggaatg agaaaattaa aaagacggtt cgaggattta tgattgaatc ttacctagca
    41041 gatggtcgtc aaaaccaacc agagatcttt ggttgctcta ttactgaccc ttgcctaggt
    41101 tgggaaaata cagaggcctt ggtagaagag atttatgtta ccttgacaaa ataagtgaaa
    41161 aggatggagt tggggaatct caactccttt tgatgagaat gatagttgga cacggaattg
    41221 acatcgaaga attggcttcg atagaaagcg cagttacacg acatgaagga tttgctaagc
    41281 gtgtactgac cgctcaggaa atggagcgct tcaccagtct caaaggacgc aggcaaatag
    41341 aatatttagc tggtcgctgg tcggctaagg aggccttttc caaggctatg ggaacgggca
    41401 ttagcaagct cggttttcag gatttggaag tcttgaacaa tgaacgtggg gcgccttatt
    41461 ttagtcaggc accattttca ggaaagattt ggctgtctat cagccacacc gatcagtttg
    41521 tgacagccag tgtcattttg gaggaaaatc atgaaagcta gtccacatag accaaccaag
    41581 gctctgattc atctgggagc tattcgacaa aatattcagc aaatgggggc tcatatccct
    41641 caaggaacgc tcaagttggc tgtggttaag gccaatgctt atggtcatgg agctgttgcc
    41701 gttgccaagg caattcaaga tgatgttgat ggcttttgcg tttccaatat cgatgaagcc
    41761 attgaactca gacaagctgg actcagcaag ccaatcctca ttttaggagt ttctgaaatc
    41821 gaagctgttg ctctagctaa agaatatgac ttcaccttga cagtggctgg actggagtgg
    41881 attcaagcac tcttagataa ggaagtggac ctaactggat tgacagtcca cctcaagatt
    41941 gattcaggga tgggacggat tggttttaga gaggcaagtg aggttgagca ggctcaagat
    42001 ttgctccaac aacacggtgt ttgtgttgaa ggaatcttta cccactttgc tactgctgat
    42061 gaggaatcag atgactattt taatgcccag ttagaacggt ttaaaactat tttagctagt
    42121 atgaaggaag ttccagagct ggttcatgct agcaattctg caacgactct ttggcatgta
    42181 gagactattt tcaatgcggt tcgtatggga gatgccatgt atggcctcaa tccaagtgga
    42241 gcggtcttgg atttgcctta tgatttgata ccggccttga ccttggagtc tgctctggtt
    42301 catgtcaaga cagttccagc tggagcttgc atgggctatg gagcaactta tcaagcggat
    42361 agcgagcaag tcatcgcgac cgtgccaatc gggtatgcag atggatggac aagagacatg
    42421 caaaatttct ctgtcttggt agatggccaa gcttgcccaa ttgtcggcag ggtttcgatg
    42481 gaccaaatca ctattcgatt gcctaagctt tatccgctag gaaccaaggt aaccttgatt
    42541 ggctccaatg gggataagga aatcactgca actcaggtag cgacctaccg cgtaaccatt
    42601 aactatgagg tggtttgcct cctcagcgac cgtattccga gagaatatta ttagaaaaga
    42661 aaggagtgga gcatgaatct acatcaaccc ttgcatgtct tgcctggtgt gggaccaaag
    42721 tcagcagaaa aatacgccaa actaggaatt gaaaacttgc aagatctctt gctctacttt
    42781 cctttccgtt atgaagactt caaaaccaag caggtgctgg agctggaaga cggtgagaag
    42841 gcagttcttt ctggtcaggt agtgactcct gctagtgtcc agtattatgg tttcaagcgc
    42901 aatcgcctgc gttttagtct caagcaggga gaggtcgttt ttgcggtgaa tttctttaac
    42961 cagccctatc tggctgataa aatagagttg ggagcaaccc ttgctgtctt tggaaaatgg
    43021 gaccgcgcta aggctagtct gactgggatg aaggttctgg ctcaggtaga agatgacctc
    43081 cagcctgtct atcgtctggc tcagggaatc agtcaggcca gtctggtcaa ggtcatcaag
    43141 acggcttttg atcagggact ggacctcttg atagaagaaa atctgcccca gtctttacta
    43201 gacaaataca aactcatgtc ccgttgtcag gcagtccgtg ctatgcattt tccaaagtat
    43261 ttggcagaat acaagcaggc tcttcgccgt ataaagtttg aggaactctt ttatttccaa
    43321 atgcagctgc agatgctcaa gtctgaaaat agagttcagg gaagtggtct ggttctgaat
    43381 tggtctcagg aaaaagtgac agcagttaaa gtaagtcttc cttttgccct gacccaagct
    43441 caggaaaaga gtttgcagga aattttaact gatatgaagt ccgaccacca catgaatcgt
    43501 ctcctacaag gggatgtggg gagtggaaaa acggtagtcg ctggcttggc catgtttgcg
    43561 gcagtgacag caggttatca ggctgcccta atggtaccaa cagaaatcct cgcagagcaa
    43621 cactttgaga gtttacagaa cctttttccc aatttgaaac tggctctctt gacaggttcc
    43681 ttgaaagctg cagaaaagag agaagtcttg gagaccattg ccaagggtga ggctgatttg
    43741 attataggaa ctcacgctct gatacaagat ggggtggagt atgctcgtct tggtttgatt
    43801 attatcgatg agcagcaccg ttttggtgta gggcaaaggc gtattttacg ggaaaaaggt
    43861 gacaatccag atgtcctcat gatgacggcg actcccattc cacggacgct tgccatcaca
    43921 gcctttggag atatggatgt ttccattatc gaccagatgc cagcaggtcg gaagcctatt
    43981 gtgacgcgct ggatcaaaca tgagcaacta cctcaggtct tgacttggtt agagggggaa
    44041 attcaaaaag gttcccaagt ctatgtcatc tctcctttga ttgaagaatc agaagctcta
    44101 gatttgaaaa atgccattgc cttatcagag gagttgacga ctcattttgc aggcaaggca
    44161 gaggtggctc ttctacatgg taggatgaag agtgacgaaa aagaccagat catgcaggat
    44221 ttcaaggaga gaaagacgga tattctggtt tcgacgacgg ttattgaggt tggggtcaac
    44281 gttcccaatg cgactgtcat gattatcatg gatgccgatc gcttcggtct cagtcaactt
    44341 caccagctta gaggtcgtgt cggtcggggg gacaagcagt cctacgctgt tctcgttgct
    44401 aatcccaaga cggattctgg gaaagaccgc atgcgtatca tgacagaaac gaccaatgga
    44461 tttgtccttg cggaggaaga tttgaaaatg cgtggttctg gtgagatttt tggaaccaga
    44521 cagtcaggac ttccagagtt ccaagtggct gatattatcg aagattttcc gattttagaa
    44581 gaagcaagaa aggttgctag ctacattagt tctatagaag cttggcaaga agatccagag
    44641 tggcgcatga ttgcccttca tctggaaaag aaagaacatc tggattaagc tttctctaag
    44701 gaaaacttaa gctagttttt aggtttggct cttatactaa agtcatcaaa aagaaacgag
    44761 gactctcata tgacagtaac gattaaagta aattaccaaa ccactttcca aaagaaggaa
    44821 gcaaaaaact agtataaaca gaagagagag cgaaatgctc tttttcgttt ctaaaactac
    44881 tttcagccca tcatcctaaa agtaaagaat ctaaattcac tttctattta tccttctttc
    44941 ttgcattgat tacatagata tgctacagtt gtggtaacga ttacaaaata aaaggagcat
    45001 gctatgaaaa atccagcttt gctagaagaa attaagacct atagaggaag ggatgaggtt
    45061 ccggaagact ttgatgcttt ctgggatggg gaagtgaaaa atgtttccac gcttccatcc
    45121 taccacttgg aggaaagaga tttccacatt cctcaagtca agtgctatga gttaacattt
    45181 gaaggaagca aggaaggaaa ggtctatgca cgcattgttc ttccaaagag tgaggagaag
    45241 gttccattaa tcttccattt tcatggttat atgggacgtg gctgggactg ggccgacatg
    45301 ctgggcttca ccgtagctgg ttacggtgtt gtttccatgg atgtgcgggg ccagtcaggt
    45361 tactcacaag acggcttgcg ttctccttta ggaaataccg tgaaggggca tattatccgt
    45421 ggtgctgtgg aaggtcggga ccacctcttt tataaggatg tttatctgga tatttaccag
    45481 ttggtcgaaa ttgttgctag tctgtctcag gttgatgaga agcgtctttc tagctatggt
    45541 gcctcacaag gaggggctct agccctagtt gcagcagcgc tcaatcctcg aattcagaaa
    45601 acagttgcca tttatccctt cttgtcagac ttcagacggg tgattgagat tggtaatact
    45661 agcgaggctt acgacgaact tttccgttat ttcaagtttt acgacccctt ccatgaaaca
    45721 gaggaggaaa tcatggcgac ccttgcctat atcgatgtca aaaatcttgc ccatcgtatc
    45781 caaggtgagg ttaagatgat tacgggcttg gacgacgatg tttgctatcc cattacccag
    45841 tttgcgattt ataatcgtct gacctgcgat aaaacctatc gtatcatgcc tgagtatgct
    45901 cacgaagcca tgaatgtatt tgttaatgac caagtctaca actggctctg tggaagtgag
    45961 attcctttta aatatctaaa ataaggagtc gactctaagc acaaaatctt aaaaattaca
    46021 aacacgcata gtatcagggg attaagaaaa cttgatacta tgcgttttat catagaaata
    46081 tagtaaaatg aaacaagaac aggacaaatc gatcaggaca gtcaaatcga tttctaacaa
    46141 tgttttagaa gtagatgtgt actattctag tttcaatcta ttatatttat agaatttttt
    46201 gttgctagat ttgtcaaatt gcttaaaata atttttttca gaaagcaaaa gccgatacct
    46261 atcgagtagg gtagttcttg ctatcgtcag gcttgtctgt aagtgttaat acttttcaaa
    46321 aatctcttca aaccacgtca gcttcgcctt gccgtatata tgttactgac ttcgtcagtt
    46381 ctatctgcca cctcaaaacg gtgttttgag catcatgcgg ctagcttctt agtttgctct
    46441 ttgattttca ttgagtataa aaacagatga gtttctgttt tctttttatg gactataaat
    46501 gttcagctga aactactttc aaggacatta ttatataaaa gaattttttg aaactaaaat
    46561 ctactatatt acactatatt gaaagcgttt taaaaatgag gtataataaa tttactaacg
    46621 cttataaaaa gtgatagaat ctatctttat gtatatttaa agatagattg ctgtaaaaat
    46681 agtagtagct atgcgaaata acagatagag agaagggatt gaagcttaga aaaggggaat
    46741 aatatgatat ttaaggcatt caagacaaaa aagcagagaa aaagacaagt tgaactactt
    46801 ttgacagttt ttttcgacag ttttctgatt gatttatttc ttcacttatt tgggattgtc
    46861 ccctttaagc tggataagat tctgattgtg agcttgatta tatttcccat tatttctaca
    46921 agtatttatg cttatgaaaa gctatttgaa aaagtgttcg ataaggattg agcaggaagt
    46981 atggtgtaaa tagcataggc tgatgtccat catttgctta taaagagata ttttagttta
    47041 attgcagcgg tgtcctggta gataaactag attggcagga gtctgattgg agaaaggaga
    47101 ggggaaattt ggcaccaatt tgagatagtt tgtttagttc atttttgtca tttaaatgaa
    47161 ctgtagtaaa agaaagttaa taaaagacaa actaagtgca ttttctggag taaatgtctt
    47221 atttcagaaa tcgggatata gatatagaga ggatcagtat gaatcggagt gttcaagaac
    47281 gtaagtgtcg ttatagcatt aggaaactat cggtaggagc ggtttctatg attgtaggag
    47341 cagtggtatt tggaacgtct cctgttttag ctcaagaagg ggcaagtgag caacctctgg
    47401 caaatgaaac tcaactttcg ggggagagct caaccctaac tgatacagaa aagagccagc
    47461 cttcttcaga gactgaactt tctggcaata agcaagaaca agaaaggaaa gataagcaag
    47521 aagaaaaaat tccaagagat tactatgcac gagatttgga aaatgtcgaa acagtgatag
    47581 aaaaagaaga tgttgaaacc aatgcttcaa atggtcagag agttgattta tcaagtgaac
    47641 tagataaact aaagaaactt gaaaacgcaa cagttcacat ggagtttaag ccagatgcca
    47701 aggccccagc attctataat ctcttttctg tgtcaagtgc tactaaaaaa gatgagtact
    47761 tcactatggc agtttacaat aatactgcta ctctagaggg gcgtggttcg gatgggaaac
    47821 agttttacaa taattacaac gatgcaccct taaaagttaa accaggtcag tggaattctg
    47881 tgactttcac agttgaaaaa ccgacagcag aactacctaa aggccgagtg cgcctctacg
    47941 taaacggggt attatctcga acaagtctga gatctggcaa tttcattaaa gatatgccag
    48001 atgtaacgca tgtgcaaatc ggagcaacca agcgtgccaa caatacggtt tgggggtcaa
    48061 atctacagat tcggaatctc actgtgtata atcgtgcttt aacaccagaa gaggtacaaa
    48121 aacgtagtca actttttaaa cgctcagatt tagaaaaaaa actacctgaa ggagcggctt
    48181 taacagagaa aacggacata ttcgaaagcg ggcgtaacgg taaaccaaat aaagatggaa
    48241 tcaagagtta tcgtattcca gcacttctca agacagataa aggaactttg atcgcaggtg
    48301 cagatgaacg ccgtctccat tcgagtgact ggggtgatat cggtatggtc atcagacgta
    48361 gtgaagataa tggtaaaact tggggtgacc gagtaaccat taccaactta cgtgacaatc
    48421 caaaagcttc tgacccatcg atcggttcac cagtgaatat cgatatggtg ttggttcaag
    48481 atcctgaaac caaacgaatc ttttctatct atgacatgtt cccagaaggg aagggaatct
    48541 ttggaatgtc ttcacaaaaa gaagaagcct acaaaaaaat cgatggaaaa acctatcaaa
    48601 tcctctatcg tgaaggagaa aagggagctt ataccattcg agaaaatggt actgtctata
    48661 caccagatgg taaggcgaca gactatcgcg ttgttgtaga tcctgttaaa ccagcctata
    48721 gcgacaaggg tgatctatac aagggtaacc aattactagg caatatctac ttcacaacaa
    48781 acaaaacttc tccatttaga attgccaagg atagctatct atggatgtcc tacagtgatg
    48841 acgacgggaa gacatggtca gcgcctcaag atattactcc gatggtcaaa gccgattgga
    48901 tgaaattctt gggtgtaggt cctggaacag gaattgtact tcggaatggg cctcacaagg
    48961 gacggatttt gataccggtt tatacgacta ataatgtatc tcacttaaat ggctcgcaat
    49021 cttctcgtgt catctattca gatgatcatg gaaaaacttg gcatgctgga gaagcggtca
    49081 acgataaccg tcaggtagac ggtcaaaaga tccactcttc tacgatgaac aatgaacgtg
    49141 cgcaaaatac agaatcaacg gtggtacaac taaacaatgg agatgttaaa ctctttatgc
    49201 gtggtttgac tggagatctt caggttgcta caagtaaaga cggaggagtg acttgggaga
    49261 aggatatcaa acgttatcca caggttaaag atgtctatgt tcaaatgtct gctatccata
    49321 cgatgcacga aggaaaagaa tacatcatcc tcagtaatgc aggtggaccg aaacgtgaaa
    49381 atgggatggt ccacttggca cgtgtcgaag aaaatggtga gttgacttgg ctcaaacaca
    49441 atccaattca aaaaggagag tttgcctata attcgctcca agaattagga aatggggagt
    49501 atggtatctt gtatgaacat actgaaaaag gacaaaatgc ctatacccta tcatttagaa
    49561 aatttaattg ggactttttg agcaaagatc tgatttctcc taccgaagcg aaagtgaagc
    49621 gaactagaga gatgggcaaa ggagttattg gcttggagtt cgactcagaa gtattggtca
    49681 acaaggctcc aacccttcaa ttggcaaatg gtaaaacagc gactttccta actcagtatg
    49741 atagcaagac cttgttgttt gcagtagata aggaagatat cggacaggaa attattggta
    49801 tagctaaagg aagcatcgaa agtatgcata atcttcctgt aaatctagca ggtgccagag
    49861 ttcctggcgg agtaaatggt agcaaagcag cggtgcatga agttccagaa tttacagggg
    49921 gagttaatgg tacagagcca gctgttcatg aaatcgcaga gtataaggga tctgattcgc
    49981 ttgtaactct tactacaaaa gaagattata cttacaaagc tcctcttgct cagcaggcac
    50041 ttcctgaaac aggaaacaag gagagtgacc tcctagcttc actaggacta acagctttct
    50101 tccttggtct gtttacgcta gggaaaaaga gagaacaata agagaagaat tctaaacatt
    50161 tgattttgta aaaatagaag gagatagcag gttttcaagc ctgctatctt tttttgatga
    50221 cattcaggct gatacgaaat cataagaggt ctgaaactac tttcagagta gtctgttcta
    50281 taaaatatag tagattgaaa taagatgtga acaactctat caggaaagtc aaattaattt
    50341 atagaaaaat tttagcagtc aaggtgtact gttatagatt caatatatta tgtgactatt
    50401 aaccttctct tctcctaaaa ttgactttct tgttttctta tcttgtccac tcgaaacaag
    50461 tat
//
LOCUS       DAVKAU010000010        48673 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVKAU010000010 DAVKAU010000000
VERSION     DAVKAU010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48673
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.010"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            107..2740
                     /gene="polA"
                     /locus_tag="VWX48_000670"
     CDS             107..2740
                     /gene="polA"
                     /locus_tag="VWX48_000670"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU9171333.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGVKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHIELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2825..3262
                     /locus_tag="VWX48_000671"
     CDS             2825..3262
                     /locus_tag="VWX48_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU9171334.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            3297..3377
                     /locus_tag="VWX48_000672"
                     /pseudo
     CDS             3297..3377
                     /locus_tag="VWX48_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(3625..4635)
                     /locus_tag="VWX48_000673"
     CDS             complement(3625..4635)
                     /locus_tag="VWX48_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU9171335.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            4784..5953
                     /locus_tag="VWX48_000674"
     CDS             4784..5953
                     /locus_tag="VWX48_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9171336.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            5950..6720
                     /gene="recO"
                     /locus_tag="VWX48_000675"
     CDS             5950..6720
                     /gene="recO"
                     /locus_tag="VWX48_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU9171337.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            6717..7709
                     /gene="plsX"
                     /locus_tag="VWX48_000676"
     CDS             6717..7709
                     /gene="plsX"
                     /locus_tag="VWX48_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU9171338.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRVKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            7715..7948
                     /locus_tag="VWX48_000677"
     CDS             7715..7948
                     /locus_tag="VWX48_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9171339.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            7994..8285
                     /locus_tag="VWX48_000678"
                     /pseudo
     CDS             7994..8285
                     /locus_tag="VWX48_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            8488..8718
                     /gene="blpU"
                     /locus_tag="VWX48_000679"
                     /pseudo
     CDS             8488..8718
                     /gene="blpU"
                     /locus_tag="VWX48_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            9433..11586
                     /locus_tag="VWX48_000680"
     CDS             9433..11586
                     /locus_tag="VWX48_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU9171340.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELVEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            11599..12948
                     /locus_tag="VWX48_000681"
     CDS             11599..12948
                     /locus_tag="VWX48_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU9171341.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            13118..13825
                     /locus_tag="VWX48_000682"
     CDS             13118..13825
                     /locus_tag="VWX48_000682"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU9171342.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            14027..17752
                     /locus_tag="VWX48_000683"
     CDS             14027..17752
                     /locus_tag="VWX48_000683"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU9171343.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISEIRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVEIAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            17845..19287
                     /locus_tag="VWX48_000684"
     CDS             17845..19287
                     /locus_tag="VWX48_000684"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU9171344.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            19324..20346
                     /locus_tag="VWX48_000685"
     CDS             19324..20346
                     /locus_tag="VWX48_000685"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU9171345.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGAIGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            20343..20888
                     /gene="purN"
                     /locus_tag="VWX48_000686"
     CDS             20343..20888
                     /gene="purN"
                     /locus_tag="VWX48_000686"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU9171346.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            20972..21481
                     /locus_tag="VWX48_000687"
     CDS             20972..21481
                     /locus_tag="VWX48_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9171347.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            21506..23053
                     /gene="purH"
                     /locus_tag="VWX48_000688"
     CDS             21506..23053
                     /gene="purH"
                     /locus_tag="VWX48_000688"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU9171348.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            23175..24437
                     /gene="purD"
                     /locus_tag="VWX48_000689"
     CDS             23175..24437
                     /gene="purD"
                     /locus_tag="VWX48_000689"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU9171349.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRTAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKASK"
     gene            24840..25328
                     /gene="purE"
                     /locus_tag="VWX48_000690"
     CDS             24840..25328
                     /gene="purE"
                     /locus_tag="VWX48_000690"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU9171350.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRILSVEDKSIADALANFAEEQGKITEESSNE
                     LI"
     gene            25315..26415
                     /gene="purK"
                     /locus_tag="VWX48_000691"
     CDS             25315..26415
                     /gene="purK"
                     /locus_tag="VWX48_000691"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU9171351.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALADSADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTI
                     VPARISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSI
                     EACDFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYG
                     KIEAKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            26425..26652
                     /locus_tag="VWX48_000692"
     CDS             26425..26652
                     /locus_tag="VWX48_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU9171352.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            26715..28013
                     /gene="purB"
                     /locus_tag="VWX48_000693"
     CDS             26715..28013
                     /gene="purB"
                     /locus_tag="VWX48_000693"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU9171353.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(28068..31994)
                     /gene="strH"
                     /locus_tag="VWX48_000694"
     CDS             complement(28068..31994)
                     /gene="strH"
                     /locus_tag="VWX48_000694"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9171354.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPATEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKKIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDIL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEILSQPAPAEESK
                     ALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(32310..33026)
                     /locus_tag="VWX48_000695"
     CDS             complement(32310..33026)
                     /locus_tag="VWX48_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9171355.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            33374..35161
                     /locus_tag="VWX48_000696"
     CDS             33374..35161
                     /locus_tag="VWX48_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU9171356.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRNPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            35158..35634
                     /locus_tag="VWX48_000697"
     CDS             35158..35634
                     /locus_tag="VWX48_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9171357.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            35662..36567
                     /locus_tag="VWX48_000698"
     CDS             35662..36567
                     /locus_tag="VWX48_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9171358.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVAYGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            36554..37369
                     /locus_tag="VWX48_000699"
     CDS             36554..37369
                     /locus_tag="VWX48_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9171359.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFASLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            37376..37780
                     /locus_tag="VWX48_000700"
     CDS             37376..37780
                     /locus_tag="VWX48_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9171360.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            38074..39240
                     /locus_tag="VWX48_000701"
     CDS             38074..39240
                     /locus_tag="VWX48_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU9171361.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            39356..40393
                     /locus_tag="VWX48_000702"
     CDS             39356..40393
                     /locus_tag="VWX48_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU9171362.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            40599..41453
                     /locus_tag="VWX48_000703"
     CDS             40599..41453
                     /locus_tag="VWX48_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9171363.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            41603..41860
                     /locus_tag="VWX48_000704"
     CDS             41603..41860
                     /locus_tag="VWX48_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="HEU9171364.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQLLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(42028..42264)
                     /locus_tag="VWX48_000705"
     CDS             complement(42028..42264)
                     /locus_tag="VWX48_000705"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171365.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDRTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLMWFEEIFEEYKSLHNKTHITKVLMN"
     gene            complement(42318..42614)
                     /locus_tag="VWX48_000706"
     CDS             complement(42318..42614)
                     /locus_tag="VWX48_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9171366.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(42604..42765)
                     /locus_tag="VWX48_000707"
     CDS             complement(42604..42765)
                     /locus_tag="VWX48_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU9171367.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            42835..43599
                     /locus_tag="VWX48_000708"
     CDS             42835..43599
                     /locus_tag="VWX48_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU9171368.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(43833..43991)
                     /locus_tag="VWX48_000709"
     CDS             complement(43833..43991)
                     /locus_tag="VWX48_000709"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171369.1"
                     /translation="MRTKASIRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTARRR"
     gene            44209..45588
                     /locus_tag="VWX48_000710"
     CDS             44209..45588
                     /locus_tag="VWX48_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9171370.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAQTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGCLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIASRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMLLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            45602..46267
                     /locus_tag="VWX48_000711"
     CDS             45602..46267
                     /locus_tag="VWX48_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU9171371.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            46381..46476
                     /locus_tag="VWX48_000712"
                     /pseudo
     CDS             46381..46476
                     /locus_tag="VWX48_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            46622..47160
                     /locus_tag="VWX48_000713"
                     /pseudo
     CDS             46622..47160
                     /locus_tag="VWX48_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            47227..47637
                     /locus_tag="VWX48_000714"
     CDS             47227..47637
                     /locus_tag="VWX48_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU9171372.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            47753..>48673
                     /gene="pavB"
                     /locus_tag="VWX48_000715"
     CDS             47753..>48673
                     /gene="pavB"
                     /locus_tag="VWX48_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU9171373.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVKD"
BASE COUNT        13535 a         9335 c        11571 g        14232 t
ORIGIN      
        1 ttactaaatt ctctggctct atctatttat tcggaaaaag tttgaaaaat acttgctcta
       61 gctcttccca atggtatttt ttgattcttt cctttataat gggtgtatgg ataagaaaaa
      121 attattattg attgatgggt cttctgtagc ttttcgggcg ttttttgcgc tgtatcagca
      181 gttggaccgt tttaagaatg cggctggttt gcataccaat gcgatttatg gtttccagtt
      241 gatgttgagt catttgttgg agcgggttga gccgagtcat attttggtgg cttttgatgc
      301 gggaaagacg accttccgga cagagatgta tgcggactat aagggtggtc gggccaagac
      361 tcctgatgag tttcgtgagc aatttccttt cattcgtgag ttgctggatc atatggggat
      421 tcgtcactat gagctggctc agtatgaggc ggatgacatc attgggacgc tggataagct
      481 agcagagcag gatggttttg atattaccat tgtcagtggg gacaaggatt tgattcagct
      541 gacggatgag catacggtgg ttgaaatttc caagaaaggt gtggctgagt ttgaggcctt
      601 tacgccagat tacctcatgg aagaaatggg cctcacacca gctcagttta tcgatctcaa
      661 ggcgctcatg ggtgataagt cggataatat ccctggggtg accaaagtcg gtgaaaagac
      721 gggtgttaag ctcttgctgg agcatggttc gcttgagggg atttatgaaa atattgatgg
      781 aatgaagact tctaagatga aggaaaatct catcaatgac aaggaacagg cctttttgtc
      841 taaaacacta gcgaccattg ataccaaggc accgattgcg attggtttag aggacttggt
      901 ctatagtggt ccagatgttg aaaatcttgg gaaattttac gatgagatgg gcttcaaaca
      961 gctcaagcag gctttaaatg tgtcgtcagc tgatgtggct gagggtttgg attttactat
     1021 tgttgaccaa atcagtcaag atatgctgag tgaagagtct atcttccaca ttgagctttt
     1081 tggtgagaat taccatacgg ataatttggt tggatttgcc tggtcttgtg gggataagct
     1141 ctatgccaca gacaagcttg agctgttgca agacccgatt ttcaaggatt tcttagaaaa
     1201 aacatctctg agagtttatg actttaagaa ggttaaagtt cttttgcaac gttttggtgt
     1261 ggatttgcag gcgcctgctt ttgacatccg tttggctaaa tacctccttt cgactgtgga
     1321 ggacaatgaa attgcgacca tcgctagtct ttatggtcag acttacttgg ttgatgatga
     1381 aactttctac ggtaagggtg ttaaaaaggc cattcctgaa cgtgagaaat tcttggaaca
     1441 cttagcttgt aaacttgctg ttttggtaga aacagagcct attttacttg aaaaactcag
     1501 cgaaaatggg caattagagc ttctttatga tatggagcaa cctctggctt ttgtccttgc
     1561 caagatggaa attgctggga ttatggtcaa gaaagagacc ttgcttgaga tgcaggctga
     1621 aaatgagctt gtcattgaaa aactgactca agagatttac gagctggctg gtgaggagtt
     1681 taatgtcaac tcgcctaagc agttgggcgt gcttctcttt gagaaattgg gacttcctct
     1741 agaatacact aagaaaacca agacaggtta ttcgacagca gtggatgttt tggagcgtct
     1801 cgctcctatt gctccgattg ttaagaaaat cctggattac cgtcaaattg ctaagattca
     1861 atctacttat gtaattggct tgcaggactg gattttggct gatggaaaga ttcatactcg
     1921 ctatgtgcag gatttgaccc aaaccgggcg tttgtctagt gtggatccaa acttgcaaaa
     1981 tattcctgcc cgattggaac aggggcgctt gattcggaag gcttttgtgc cagagtggga
     2041 ggatagtgtg ctactcagct ctgactattc acagattgaa ttgcgcgttt tggcgcatat
     2101 ttctaaggat gagcacttga ttaaggcctt ccaagagggg gcagatatcc atacttcgac
     2161 agccatgcgg gtctttggca ttgagcgtcc tgatgatgtg actgcaaacg accgtcgcaa
     2221 tgccaaggca gttaactttg gagtggttta tgggatttca gactttggct tgtctaataa
     2281 tttgggaatt agtcgtaagg aagctaaagc ctacattgat acctactttg aacgttttcc
     2341 aggtattaaa aactacatgg atgaagtggt gcgggaggcg cgtgataagg gctatgtaga
     2401 gaccctcttt aagcgtcgcc gtgagttgcc agatatcaat tcgcgcaact tcaatattcg
     2461 tggttttgcg gagcgaactg ctatcaactc acctatccag ggttcggcag cagatattct
     2521 caagattgcc atgattcagc tggataaagc cttggttgca ggtggttatc agactaagat
     2581 gctgttacaa gtgcacgatg aaatcgtcct tgaagtgcct aaatctgaat tggtagagat
     2641 gaaaaaattg gtgaaacaaa ccatggaaga agccattcaa ctcagtgttc ctcttatcgc
     2701 agatgagaat gaaggggcaa cctggtacga ggctaaataa aaagggggct agtcctcctt
     2761 ttttgtagta gaattctgca aaccttttca aaatgtgcta tactgatgaa aaaggaggat
     2821 ttctatgagt caagaattta tcaatccaag tgatggcgtg attcgtcagt atctcgcaac
     2881 gagtaaaacc cttgctgtgg tgggtttgtc tgaccgtgaa gaaacaacca gcaatcgagt
     2941 aacaaaggaa atgcaggctc ggggctataa aatcatccca gtcaatccca aggcggcagg
     3001 tggcgaaatc ttgggtgaaa aggcttatgc tagcctcgct gaaattcctt ttcctgtaga
     3061 tattgtcaat gtttatcgtc gcagtgaatt tctgcccgat gtggcgcgtg attttctcaa
     3121 agctgatgcc aagatttttt gggcacagct aggacttgaa agtttagaag cgaaagagat
     3181 tttgcgtgat ggtggatgtg atgatatcgt gatgaatcgc tgtatcaaga gagaacatac
     3241 tcgcttgatt gaggaagcat aagaaaaagg tagctgatgg gctacctttt gtgttatact
     3301 caatgaaaat caaagagcaa actaggaaac tagctgcggg ttgctcaaaa cactgttttg
     3361 aggttgtaga tagaactgac gaagtcagct caaaacaccg ttttgaggtt gtagatagaa
     3421 ctgacgaagt cagctcaaaa caccgttttg aggttgcaga tagaactgac gaagtcagct
     3481 caaaacaccg ttttgaggtt gcagatagaa ctgacgaagt cagctcaaaa caccgttttg
     3541 aggttgcaga tagaactgac gaagtcagta acatatatac ggcaaggcga cgttgacgtg
     3601 gtttgaagag attttcgaag agtattagaa aatgccgata agggtctgca taccaaggct
     3661 ggtgaggatg atggcaatcc agcagacggc tccgagaaca atggattttc cactggattt
     3721 gaccatagcg accagattag ttttgagacc gatggcactc atggccatga taatgaggaa
     3781 tttagagagt tgtttgagag gggtaaagaa actactagac acaccgagag aggtcagaag
     3841 ggtggttagg agcgatgcaa ggatgaagta aaggataaaa agtgggaaga cttttttcag
     3901 ttgtaagcct tgcttatttt tttgctcgcg actttgccag taggagagaa agagagtgat
     3961 ggggatgata gctagggtgc gcgtgagttt gacaatggtt gcggattcga gggtattggt
     4021 ctggtagaga ctgtcccaag cgctagctgt ggcggttaca gaggaagtat cattgaccgc
     4081 agttcctgca aagagggcga agccgtcatt ggatagatga agccaggtgc cgagggttgg
     4141 aaagatgagc gcagccaaga cattgaagaa aaagataacg gagatggctt gggctacttc
     4201 cttttcctta gcatggataa caggcgctgt cgctgcaatg gcagaacccc cacagataga
     4261 agaacctact ccaatcaagg tagccagttt tgtatccagg gcaaagaagc gctggaagag
     4321 gtaggcaaca atcaaggcta ttgaaatggt ggaaaggatg acagggagtg aagattgccc
     4381 aactgcgaag acttgagaga tattgagacc aaaaccaagt aagataacgg catactggag
     4441 caatttcttg gaactaaagg tcaatccaac atccagttgt ttataagacg agagaaaggg
     4501 atgtaggagc atgcccataa aaatcgcaaa aacgggtgcg ccaataacag ggaagaatcc
     4561 tcctaagtac caagatagga tggaaatgag aaggcagacc aagatgcctg ctccattttt
     4621 tgatagaaat gacataaaaa cctccaaata gaatctgtta ccattataga cctgtaaaca
     4681 ggaaaagtaa aatagaaagt ggaaagctat tctctaatgt atttttgcgg tcgggaggct
     4741 tttgtagtat aatagagata cgttttgaaa gtaggaggta tctatggact taactaagcg
     4801 ctttaataaa cagttagata aaattcaagt ttcgttgatt cgtcagtttg accaggctat
     4861 ttcggagatt cctggggtct tgcgtttgac cttgggggaa cctgatttta caacgccaga
     4921 ccatgtcaag gaggcggcca agcgagcgat tgatcagaac caatcctact atacagggat
     4981 gagtggtctg ctgactctac gtcaggcggc cagtgatttt gttaaggaaa agtaccaact
     5041 ggactatgct cctgaaaatg aaatcttggt cactatcgga gcgacagagg ctttatctgc
     5101 gactttgacg gctattttgg aagagggaga caaggtgctc ttgccagctc ctgcttatcc
     5161 gggttatgaa ccgatcgtca atctagttgg ggcagaaatt gttgagattg atacgactga
     5221 aaatggtttt gtcttgactc ctgagatgtt ggagaaggcc attttggagc agggtgataa
     5281 gctcaaggcg gttattctca actatccagc caatccgaca ggaattacct acagtcgaga
     5341 gcagttagag gccttggcag ctgttttacg caagtacgaa atttttgttg tctgtgatga
     5401 ggtttactca gaattgacct acacgggcga agcccatgtg tctctaggaa cgatgttgag
     5461 agaccaggct attattatca atggtttgtc taaatcgcat gccatgacag gttggcgttt
     5521 ggggctgatt tttgctcctg cgaccttcac agcccagtta atcaagagtc accagtactt
     5581 ggtcactgcc gcaaatacca tggcgcaaca tgctgcggta gaagccttga cggctggtaa
     5641 aaacgatgcg gagcccatga agaaggaata tatccaacgt cgggactata tcatcgaaaa
     5701 aatgactgct cttggttttg agattatcaa accagacggt gccttctata tttttgctaa
     5761 aattccagcg ggctacaatc aagactcctt tgcttttctg aaggattttg ctcagaagaa
     5821 ggccgttgcc tttatccctg gtgcagcctt tggacgttac ggggaaggct acgtccgcct
     5881 atcttatgca gccagcatgg agactatcaa agaagccatg aaacgacttg aggagtacat
     5941 gagagaagca tgattcagtc tatcacgagt caaggcttgg tgctttacaa tcgcaatttt
     6001 cgtgaggatg acaagctcgt caaaattttt acagagcagg ttggcaaacg catgtttttt
     6061 gtcaaacacg ctggtcagtc taagctggcg cctgttattc agcccttggt gctggcacga
     6121 tttctcttgc gaatcaatga tgacggactc agttacatcg aagactatca tgaggtcatg
     6181 acttttccca agattaatag tgacctcttt gtcatggcct atgcgaccta tgtggcagct
     6241 cttgcagatg ctagtttgca ggacaatcag caggatgctc ccttgtttgc ttttttgcaa
     6301 aagactttgg agttgatgga agcaggcttg gattatcagg ttttgaccaa tatttttgaa
     6361 attcaaattt tgactcgatt tggaatcagc ctcaatttta atgagtgtgt cttctgccat
     6421 cgggttggtc aggcttttga cttttctttc aaatatggag cctgtctctg tccagagcat
     6481 tatcatgagg atgagagacg ttgccatctc aatcccaata tcccctatct gctcaatcaa
     6541 tttcaagcta ttgattttga gactttggag accatttcgc tcaagcctgg aatcaagcaa
     6601 gagctacgcc aatttatgga tcaactatat gaagagtacg ttgggattca cctaaaatca
     6661 aagaaattta ttgattccct agcagactgg ggacaattac taaaagagga aaagaaatga
     6721 aaaaaatcgc agtagatgcc atggggggcg attacgcacc tcaggccatc gttgagggtg
     6781 tcaatcaagc cctatctgac ttttcagata tcgaggttca actctacgga gatgaagcta
     6841 aaatcaagca atatctgaca gcgacagagc gcgtcagcat tatccatacg gatgagaaga
     6901 ttgattcgga tgatgaacct acgagagcta ttcggaataa gaaaaatgcc agtatggtat
     6961 tggcagccaa ggctgtcaaa gatggtgaag cagacgctgt cctttcggct gggaatacag
     7021 gtgctttgtt ggctgctgga ttcttcatcg tgggtcgtat caagaatatc gaccgtcctg
     7081 gacttatgtc aacattgccg actgtagatg ggaaaggttt tgacatgctt gacctcggtg
     7141 ctaatgcaga aaatacagcc cagcacctcc atcaatacgc tgtcctaggt tctttctatg
     7201 ccaagaatgt tcgtggcatt gcgcaaccac gtgttggttt gctcaacaac ggaacagaga
     7261 gtagcaaggg cgacccgctt cgtaaggaaa cttatgaatt actggcggct gatgaaagtt
     7321 tgaactttat cggaaacgtg gaagcgcgtg atttgatgaa tggcgttgca gatgttgttg
     7381 tggcagatgg tttcacggga aacgctgtgc tcaaatccat cgaagggaca gctatgggaa
     7441 tcatgggctt gctcaagaca gctattacag gtggtggtct tcgagtgaaa ctaggtgccc
     7501 tccttctcaa ggacagcctc agaggtttga aaaaacagct caattattca gatgttggtg
     7561 gagcggtctt gtttggtgtc aaggcacctg ttgtcaagac tcatggctca agcgatgcca
     7621 aggctgttta tagtacgatt cgccagattc gtaccatgct agaaacagaa gtagttgccc
     7681 agactgcgcg tgaattttca ggagaataaa agagatgaaa gaaaaagaaa tttttgacag
     7741 tattgtgacc attatccaag agcgacaggg agaggacttt gtcgtgacag aatccttgag
     7801 tctgaaagac gacttggatg ctgactcagt tgatttgatg gagtttatct tgacgctgga
     7861 ggatgaattt agtatcgaaa tcagcgatga ggaaattgac caactccaaa gtgtaggaga
     7921 tgtggttaaa atcattcaag gaaaatagca atcggagttc caagtcaacg gaagtagatg
     7981 gtttttagaa atgagaaata tcggacaagc tggtaaaatc ttggctgaca gtggttatca
     8041 agggctcatg aagatatatc ctcaagcaca aacttccacg taaatccagc aaactcaagc
     8101 cgctaacagt tgaagataaa gcctgtaatc atgcgctatc taaggagaga agcaaggttg
     8161 agaatatctt tgccaaagta aaaacgttta aaatgttttc aacaacctat cgaaatcatc
     8221 gtaaacgctt cggattacga atgaatttga ttgctggtat tatcaatcat gaactaggat
     8281 tctagttttg caggaagtct aatagtaaaa aagtgattag aaaacatctt ttttaaaaat
     8341 agagatgatt ttgaaacaaa aaagctaatt caagacgttt cgatgccaat tcaagatttg
     8401 gatgaaaaaa attaatagat actgttatac taaacttgtc aagtttgtaa caagacaaat
     8461 attaaaaata aaaaagaggt attcgttatg aatacaaaaa agatgtcaca atttgaaatt
     8521 atggatactg agatgcttgc ttgagttgaa ggtggcggat gcaattgggg agattttgcc
     8581 aaagcaggtg ttggaggagg agtagcacga ggtcttcagc taggaattaa aacaagaaca
     8641 tggcaaggtg cagcaactgg tgctgcggga ggagctatac ttggaggtgt ggcctatgaa
     8701 gcgacatgtt ggtggtaatt atggatttta aaagttttat tattggttta gtagttggta
     8761 tatttggtcc ttatatggat gatttaatta gaaaaaaatt tttaaagtct tcggagaaga
     8821 aaacagaaaa atctgttaaa aaataatcaa aactataaat gatgaatctg aatcaaaatt
     8881 attttgcgca tgtaaagagg agtcttatag taacgagtca aaaaaggagt aactatgaat
     8941 cgtaatttag aacggtgtta tctattctga ctagggatag atcataccat aggtagctta
     9001 gaaatagcag agacattaga aattgaagta ataaatagga tgtcgtaagt gttactatca
     9061 atgatttatt tgtttcaagc ttgcctaggg tgtcagtaaa aaatcatttt cctttcaata
     9121 gcatattttt agtgggcagg actcttgttc tgcctatttt tttatccaaa aagtgcagtt
     9181 gggagggaga taggctcatt tgggaaggaa gtccagtttt tgtttagtga ttggggtaag
     9241 atagttgtta tcagatgagt ttatactctt cgaaaatcaa attcaaacca cgtcaacgtc
     9301 gccttgccgt atatatgtga ctgacttcgt cagtcctatc tacaacctca aaacagtgtt
     9361 ttgagcagcc tgcggctagt ttcctagttt gctctttgat tttcattgag tattagggaa
     9421 aaggagatga atatgaaatt tgggaaacgt cactatcgtc cgcaagtgga tcagatggac
     9481 tgcggtgtag cttcattagc catggttttt ggctactatg gtagttatta ttttttggct
     9541 cacttgcgag aattggctaa gacgaccatg gatgggacga cggctttggg cttggtcaag
     9601 gtggcagagg agattggttt tgagacgcga gccattaagg cggatatgac gctttttgac
     9661 ttgccggatt tgacttttcc ttttgttgcc catgtgctta aggaagggaa attgctccac
     9721 tactatgtgg tgactgggca ggataaggat agcattcata ttgccgatcc agatcccggg
     9781 gtgaagttga ctaaactgcc acgtgagcgt tttgaggaag aatggacagg agtgactctt
     9841 tttatggcac ctagtccaga ctataagcct tataaggaac aaaaaaatgg tctgctctct
     9901 tttatcccta tattagtgaa gcagcgtggc ttgattgcca atatcgtttt ggcaacactc
     9961 ttggtaaccg tgattaacat tgtgggttct tattatctgc agtctatcat tgatacctat
    10021 gtgccagatc agatgcgttc gacactaggg attatttcta ttgggctagt catcgtctac
    10081 atcctccagc aaatcttgtc ttacgctcag gagtatctct tgcttgtttt ggggcaacgc
    10141 ttgtcgattg acgtgatttt gtcctatatc aagcatgttt ttcacctccc tatgtccttt
    10201 ttcgcgacac gcaggacagg ggaaattgtg tctcgtttca cggatgctaa cagtattatc
    10261 gatgcgctgg cttcgaccat tctttcgatt ttcctagatg tgtcaacagt tgtcattatt
    10321 tcccttgttt tattttcaca aaataccaat ctctttttca tgactttatt ggcgcttcct
    10381 atctacacag tgattatctt tgcctttatg aagccgtttg aaaagatgaa tcgggacacc
    10441 atggaagcca atgcggttct gtcttcttct atcattgagg acatcaacgg tattgagact
    10501 atcaagtcct tgaccagtga aagtcagcgt taccaaaaaa ttgacaagga atttgtggat
    10561 tatctgaaga aatcctttac ctatagtcga gcagagagtc agcaaaaggc tctgaaaaag
    10621 gttgcccatc tcttacttaa tgtcggcatt ctctggatgg gggctgttct ggtcatggat
    10681 ggcaagatga gtttggggca gttgattacc tataatacct tgctggttta ctttaccaat
    10741 cctttggaaa atatcatcaa tctgcaaacc aagcttcaga cagcgcaggt tgccaataac
    10801 cgtctaaatg aagtgtatct agtagcttct gagtttgagg agaagaaaac agttgaggat
    10861 ttgagcttga tgaagggaga gatgactttc aagcaggttc attacaagta tggctatggt
    10921 cgagacgtct tgtcggatat caatttaacc gttccccaag ggtctaaggt ggcttttgtg
    10981 gggatttcag ggtcaggtaa gacgactttg gccaagatga tggttaattt ttacgaccca
    11041 agtcaagggg agattagtct gggtggtgtc aatctcaatc agattgataa aaaagcccta
    11101 cgccagtaca tcaactatct gcctcaacag ccctatgtct ttaacggaac gattttggag
    11161 aatcttcttt tgggagccaa ggaggggacg acacaggaag atatcttacg ggcggtcgaa
    11221 ttggtagaga ttcgagagga tatcgagcgc atgccactga attaccagac agaattgact
    11281 tcggatgggg cagggatttc aggtggtcaa cgtcagagaa tcgctttggc gcgtgctctc
    11341 ttgacagatg cgccggtctt gattttggat gaggcgacta gcagtttgga tattttgaca
    11401 gagaagcgga ttgtcgataa tctcatggct ttggacaaga ccttgatttt cattgctcac
    11461 cgcttgacta ttgctgagcg gacagagaag gtggttgtct tggatcaggg caagattgtc
    11521 gaagaaggaa agcatgctga tttgcttgca cagggtggct tttacgccca tttggtcaat
    11581 agctagaaag aggagaggat gaaaccagaa tttttagaaa gtgcggagtt ttataatcgt
    11641 cgttaccata atttttccag tagtgtgatt gtacccatgg cccttctgct cgtgttttta
    11701 cttggctttg caactgttgc agaaaaggag atgagtttgt ccactagagc tactgtcgaa
    11761 cctagtcgta tccttgcaaa tatccagtca actagcaaca atcgtattct tgtcaatcat
    11821 ttggaagaaa ataagctggt taagaagggg gatcttttgg ttcaatacca agaaggggca
    11881 gagggtgtcc aagcggagtc ctatgccagt cagttggaca tgctaaagga tcaaaaaaag
    11941 caattggagt atctgcaaaa gagcctgcaa gaaggggaga accactttcc agaggaggat
    12001 aagtttggct accaagccac ctttcgcgac tacatcagtc aagcaggcag tcttagggct
    12061 agtacatcgc aacaaaatga gaccatcgcg tcccagaatg cagcagctag ccaaacccaa
    12121 gccgaaatcg gcaacctcat cagtcaaaca gaggctaaaa ttcgcgatta ccagacagct
    12181 aagtcagcta tggaaacagg tgcttccttg gccagtcaga atctagccta ctctctttac
    12241 cagtcctaca agtctcaggg cgaggaaaat ccccaaacta aggttcaggc agttgcacag
    12301 gttgaagcac agatttctca gttagaatct agtcttgcta cttaccgtgt ccagtatgca
    12361 ggttcaggta cccagcaagc ctatgcgtca gggttaagca gtcaattgga atcccttaaa
    12421 tcccaacatt tggcaaaggt tggtcaggaa ttgacccttc tagcccagaa aatcttggag
    12481 gcagagtcag gtaagaaggt acagggaaat cttttagaca aggggaaaat tacggcgagt
    12541 gaggatgggg tgcttcatct taatcctgag accagtgatt ctagcatggt tgcagaaggt
    12601 gccctactag cccaacttta tccatctttg gaaagagaag ggaaagccaa actcacagcc
    12661 tatctaagtt caaaagatgt agcaagaatc aaggtcggtg attctgttcg ctatactacg
    12721 actcatgatg ccgggaatca acttttccta gattcaacta ttacaagtat tgatgcgaca
    12781 gctactaaga ctgagaaagg gaatttcttt aaaatcgagg cggagactaa tctaacttcg
    12841 gagcaggctg aaaaacttag gtacggggtg gaaggccgct tgcagatgat tacgggcaag
    12901 aaaagttatc tacgttatta tttggatcaa tttttgaaca aagagtaatg ttcgtgtttt
    12961 tagagttaaa taatttttaa actgtgagaa agattcttct tgcagttttt tctttacaat
    13021 ttttgaaaaa catctactat ttattcggtt aaattcttgt gttttttggt tttttgtggt
    13081 aaaatgtgct caagtaatac gaaaggcgaa ctttaaaatg tcaaaacaat tgatctattc
    13141 gggaaaagct aaagatatct atacaactga ggatgaaaat cttattattt caacttacaa
    13201 ggaccaggcg actgctttca acggtgtcaa gaaggagcag attgcaggta agggagtctt
    13261 gaataatcag atctcatctt ttatttttga gaaattaaat gcggctggtg tggcgactca
    13321 ctttgtggag aaactttcag acacggaaca actcaataaa aaggttaaga ttattccttt
    13381 ggaagtcgtg ctccgcaact atactgctgg ttccttttca aaacgttttg gtgtggatga
    13441 gggaatcgcc ttggagactc cgattgtcga attttactac aaaaatgatg atttggatga
    13501 tccatttatc aatgatgagc atgtgaaatt cctacagatt gcgggtgacc agcagattgc
    13561 ctacttgaag gaagaaacgc gtcgtatcaa tgaactattg aaagtctggt ttgctgagat
    13621 tgggcttaaa ttgattgact ttaagctaga gttcggtttt gacaaggatg gcaagattat
    13681 cttggcagac gaattttcac cagataactg ccgcttgtgg gacgctgatg gcaaccacat
    13741 ggataaggat gttttccgta gaggattggg agaactaacc gacgtttatg agattgtttg
    13801 ggaaaagttg caggaattga aataatctgt ttgcaacgga aaaccttcgt ctctcaacta
    13861 aaaggactca ggctgaaaag gtcccccaga ccttttcact ctgtagagaa ctaggtgaac
    13921 taacagatgt ttacgaaatt gtctgggaaa agttgcaggg tttaaaataa caacctcaag
    13981 gctgtttggg aatattgcaa gagctgaaat aaaggaataa gaattgatgg ataaacgtat
    14041 ttttgttgaa aaaaaggctg attttcaggt caagtcagag agtttggtta gagagctcca
    14101 gcacaacttg ggactgtcaa gcttgaaaag tattcgtatt gtgcaagtat atgatgtatt
    14161 tgacttggct gaggacttgt ttgcacctgc agagaagcac attttctctg agcagggaac
    14221 cgaccatgtt ttagatgaag tatctgtgca ggcggatctt gctaactatg ctttctttgc
    14281 cattgaaagt ctgccagggc agtttgacca gcgtgcagct tcgtcacagg aagccttgct
    14341 tttgttggga agttcgagtg acgtgacagt caacacagcc caactttact tggtgaataa
    14401 agatattgat gcgactgagt tggaagctgt caaaaactac ctgctcaatc cagttgattc
    14461 tcgtttcaag gatatcacga cagggattgc caagcaggag ttttcagagt cagacaagac
    14521 cattccaaaa ttgactttct ttgaaagcta tacagcagaa gactttgctc gctacaaggc
    14581 cgagcaaggg atggccatgg aagtggatga tttgctcttt atccaagact actttaagtc
    14641 aatcgggcgc gtgccaactg agactgaact caaggttttg gacacttact ggtctgacca
    14701 ctgccgtcat acgacttttg agacagagtt gaaaaacatc gacttttcag cttctaaatt
    14761 tcaaaagcaa ttgcagtcaa cctatgacaa gtatattgcc atgcgcgagg aattaggtcg
    14821 gtctgaaaaa ccacaaacct tgatggatat ggcgactatt ttcggtcgtt atgagcgtgc
    14881 taatggacga ttggatgata tggaagtctc tgacgaaatc aatgcctgct cagttgaaat
    14941 tgaagtggac gttgatggtg tcaaggaacc ttggctcctc atgtttaaaa atgaaaccca
    15001 caaccatcca acagaaattg agccatttgg tggagcggct acctgtatcg gtggagctat
    15061 tcgtgatccg ttgtcaggcc gttcctatgt ttaccaagcc atgcgtattt caggtgctgg
    15121 tgatattaca gcaccgattt cggaaattcg tgctgggaaa ttgccacaac aagtcatttc
    15181 taaaacagca gctcatggtt attcttcata tggtaaccag attgggcttg ccacaaccta
    15241 cgttcgtgaa tacttccacc caggctttgt agctaaacgt atggaacttg gtgccgttgt
    15301 tggtgcggct cccaagggca atgttgtccg tgaaaaacct gaagcaggtg atgtgatcat
    15361 ccttctcgga ggcaaaacag gtcgtgatgg tgtcggtggt gcgacgggct cttctaaggt
    15421 tcaaacagtt gagtctgtag agattgctgg tgctgaggtt caaaaaggaa atgccatcga
    15481 agaacgcaag attcagcgcc tcttccgtaa tggcaatgtc actcgtctga tcaagaagtc
    15541 caatgacttt ggggcaggcg gcgtctgtgt ggctattggt gaattggcag acggtcttga
    15601 aatcgacctc aacaaggtgc ctcttaaata ccagggcttg aatggtacag aaattgccat
    15661 ctctgaatca caagaacgga tggcggtcgt ggttcgtcct gaagatgtgg atgccttcgt
    15721 tgccgaatgt aacaaagaaa atattgatgc tgttgtggtg gcgacagtaa ctgaaaaacc
    15781 aaatcttgtc atgcactgga atggtgagac aatcgttgac ttggagcgtc gtttccttga
    15841 caccaatggt gtgcgcgtgg ttgtcgatgc caaagttgtg gacaaggatg tcaaactccc
    15901 agaagagcgt caaacatctg ctgaaacact ggaatcagat acccttacgg ttctatctga
    15961 cctcaaccat gcaagtcaaa aaggattaca gactgtcttt gactgctctg ttggacgctc
    16021 aacggttaat cacccacttg gtggtcgtta ccaactcaca ccaactgagg catctgtgca
    16081 gaaattgcca gttcaacacg gtgtgactca tactgcgtcg gtcattgctc aaggtttcaa
    16141 cccatatgta gctgaatggt ctccatacca cggtgctgct tacgcggtta tcgaagcaac
    16201 tgctcgtttg gtggctgctg gtgccaactg gtctaaggct cgtttctctt accaagaata
    16261 tttcgagcgg atggacaagc aagcagagcg ttttggtcag ccagtagccg cccttctagg
    16321 ctctattgaa gctcagattc aacttggctt gccatctatc ggtggtaagg actccatgtc
    16381 tggtaccttt gaagaattga ccgttccgcc aaccttggtt gcctttgggg tgacgacggc
    16441 agatagccgt aaggtgctct ctccagaatt taaagctgtt ggggaaaata tctactacat
    16501 cccaggtcaa gccctctctg cagagattga ttttgacttg attaagaaaa attttgctca
    16561 gtttgaagca agccaagctg accataaagt gacatctgca tcagctgtca aatacggtgg
    16621 tgtagttgaa agtttggctc ttgctacctt tggaaactat attggtgcag aggtgacctt
    16681 gcctgaactt aaaacagctt tgacagctca attaggcggc tttgtcttca catctcctga
    16741 agaaattgct ggagtagaga agattggaca aacgaaagca gactttacac tgactgtcaa
    16801 cggtgtgaag ctagatggac acaagcttga cagtgcattt caagggacat tggaagaagt
    16861 ttacccaaca gaatttaccc aagcgaaaga actagaagaa gtaccagctg tggcatcaga
    16921 tgttgtgatt aaagccaaag aaaaggttga aaaacctgtg gtttacatcc cagtctttcc
    16981 aggaaccaac tcagaatatg attcagctaa ggccttcgaa aaagaaggtg cagaggtcaa
    17041 tttggtgcca ttcgtgacct tgaatgaaga agctattgtc aagtcagttg aaactatggt
    17101 tgacaatatc gacaagacta atattctctt ctttgccggt ggattctcgg ctgcggatga
    17161 accagatggt tcagctaagt ttatcgtcaa tatcctgctt aatgaaaaag tgcgtgtggc
    17221 tattgatagc tttatcgccc gtggtggctt gattatcggt atttgtaatg gattccaagc
    17281 cttagtcaaa tcgggtctcc taccatacgg aaactttgaa gatgctaaca gtactagtcc
    17341 aaccctcttc tacaatgatg ccaaccaaca cgtggccaag atggtggaaa ctcgcattgc
    17401 caataccaac tcaccatggt tggctggtgt gcaagtgggc gatatccacg ctattcctgt
    17461 ttcgcacggt gaagggaagt ttgtcgtgac ggctgaggaa tttgcagagc tccgtgacaa
    17521 tggacaaatt ttcagccaat acgttgactt taacggtaaa ccaagtatgg attctaagta
    17581 caatccgaat ggttctgtcc atgccatcga aggaattacc agcaagaatg gtcaaatcat
    17641 cggtaagatg ggccactcag aacgttatga ggatggtctt ttccaaaata tcccaggcaa
    17701 taaagaccaa cacctgttcg catcagcggt taaacatttc actggaaaat aagacttaca
    17761 gattttctaa tagatagtat cagtaatgta aaagtcatgt aaatctagct cttgatgatt
    17821 acaaatgaaa attaggtata aaaaatgaca tacgaagtaa aatctcttaa tgaagaatgt
    17881 ggtgttttcg gtatttgggg acatccagat gctgctaagt tgacctattt tggactccac
    17941 agtcttcaac accgtggtca ggagggggca ggaatcctct ccaacgatca aggacaactg
    18001 aagcgccatc gtgacatggg gcttttatca gaagttttca gaaatccagc taatttggat
    18061 aaattgacag gagctggtgc gattgggcat gtgcgttatg cgactgctgg cgaagcttct
    18121 gtagataaca tccagccctt cctcttccgt tttcacgata tgcagtttgg cttggctcat
    18181 aatggaaatc tgaccaatgc agcctctctc aagaaagaac tggaacaaag aggagcaatt
    18241 ttcagcgcga cttcggactc tgaaatcttg gctcacctca ttcgtcgcag tcataatcct
    18301 agcctgatgg gcaaaatcaa ggaagcgctc agccttgtca aaggtggttt tgcctatatc
    18361 ttgctgtttg aggacaagtt gattgcggct cttgacccta atggctttcg tccgctttct
    18421 atcgggaaaa tggccaacgg agcggtggtt gtttcctctg aaacctgtgc ttttgaggtc
    18481 attggtgccg agtggattcg tgatttgaag ccaggtgaga ttgtgatcat tgatgacgag
    18541 ggcattcagt atgacagcta tacagatgat acccagttgg cgatttgttc tatggagtat
    18601 atctactttg cccgccctga ttctaatatc cacggtgtca atgtccatac ggcacgtaag
    18661 agaatgggag cgcaattggc gcgagaattt aagcatgagg cagatattgt agttggtgtg
    18721 cccaattctt ccctaagcgc ggctatggga tttgcggaag aatcaggctt accaaatgaa
    18781 atgggtctga tcaaaaacca atacacccag cgaactttta tccaaccgac tcaagaattg
    18841 cgggagcaag gagtgcggat gaaactgtct gctgtttcgg gtgttgtcaa aggcaaacgt
    18901 gtggtcatgg tggatgattc cattgtacgt ggaacaacct ctcgtcgtat cgttcagctc
    18961 ttgaaagaag cgggtgcgac tgaggttcac gttgccattg gaagtcctgc actagcgtat
    19021 ccatgtttct acgggattga tatccagacc cgtcaggagc tgattgcagc caatcatacg
    19081 gtcgaagaaa ctcgccaaat cattggtgcg gacagtctga cttatctttc aattgatagc
    19141 ttgattgagt cgattggtat cgaaacagat gcgccgaacg gtggtctctg tgtcgcttac
    19201 tttgacggtg actacccaac gcctctctat gactacgaag aagactatcg tagaagtttg
    19261 gaagaaaaga ccagttttta caagtaggcg acagattctc cattaaagaa aaggaaaaaa
    19321 caaatgacaa ataaaaatgc atatgcccag tcgggtgtgg atgttgaagc gggttatgaa
    19381 gttgttgaac ggattaaaaa gcacgtggcc cgtacggagc gtgcaggtgt catgggagct
    19441 attggtggct ttggtggtat gtttgacctt tccaagactg gggttaaaga acccgtcttg
    19501 atttcaggga ctgacggtgt cggaaccaag ctcatgttgg ctatcaagta cgacaagcac
    19561 gataccatcg ggcaggactg tgtggccatg tgtgtcaacg acatcattgc tgcaggtgcg
    19621 gaacccctct attttctcga ctacgtagcg acagggaaga atgaaccagc taagctagaa
    19681 caagtggttg ctggtgtggc agaaggttgt gtgcaggctg gtgctgccct catcggtggg
    19741 gaaacggctg aaatgccggg catgtacggc gaagacgact atgacttggc tggttttgcg
    19801 gtcggtgtgg ctgaaaaatc tcaaatcatt gacggttcaa aggtggtaga gggagatgtt
    19861 cttctcggac ttgcttcaag tgggattcac tcaaatggtt actctttggt tcgtcgtgtc
    19921 tttgcggatt acacaggtga ggaagtccta ccagaattgg aaggcaagaa acttaaggaa
    19981 gttctacttg agccgactcg tatctatgtc aaggctgtct tgccgctcat caaagaagag
    20041 ttggtcaacg gcattgccca catcacaggt ggtggcttta tcgaaaatgt ccctcgtatg
    20101 tttgcagatg acctagctgc tgaaattgat gaaagcaaag ttccagtact tccaattttc
    20161 aaagcccttg aaaaatatgg tcagattaaa cacgaagaaa tgtttgaaat cttcaatatg
    20221 ggtgtgggac ttatgttggc ggtcagccct gaaaatgtag agcgtgtaaa agaattgttg
    20281 gatgaagcag tctatgaaat tggtcgcatc gtcaagaaag aaaacgaaag tgtcattatc
    20341 aaatgaaaaa aatagcggtt tttgcctctg gtaatggctc aaattttcag gtgattgccg
    20401 aagaatttcc agtggagttt gtcttttcag accatcgtga tgcctatgtg cttgagcgtg
    20461 caaagcagct cggcgttctg tcctatgctt ttgaactcaa ggagtttgag agcaagacag
    20521 actacgaagc agcccttgtc gaactcttgg aagaacacca gattgacttg gtttgcctag
    20581 caggctacat gaaaatcgtt ggaccaacct tattgtcggc ttatgaaggt cggattgtca
    20641 acattcatcc agcctacttg ccagaatttc caggagctca tgggattgag gatgcttgga
    20701 atgctggcgt gggtcagtct ggtgtgacca ttcactgggt ggattcgggt gtggatacag
    20761 gccaggtcat caaacaggtt cgtgtgccac gactagctga tgataccatt gacagatttg
    20821 aagctcgcat ccatgaagca gagtacaggt tgtatccgga agtagtgaag gctctattta
    20881 cagattgact ttttgatgat tcatatgata tctttgattt taaattggag tcagtgtttg
    20941 ttgaagacgg cttcaaacgg aggtatttgt aatgttagaa tctaaaaaaa caactcgata
    21001 tgtattttat gtctatctga tgttattaac ttggggaatc ttatttaagt ttgaaacaaa
    21061 tcctgaattt atagcatttt tcttagctcc aaggtatatc aattggattc cattttcaga
    21121 accactaata gtcgatggaa aaattgtttt tgctgaaatg ttatttaatc tgatttcctt
    21181 tattccatta ggtgtttgtt tccctttgat aaaaactaat ttatctagtt taagaatagt
    21241 cgggacaggt ttcttgatta gtttattgtt tgagtgctta cagtatattt tagcaatagg
    21301 tataacagat ataacggatt tgactttaaa tacgctaggt gtctgtgtag gcttactgat
    21361 ttatcaaatt tttataagag tgttcaaatc acagactaga aaatggatca atatcttagg
    21421 tatgcttagc cttggttttg cttatcttgt tttactgtta ctgcatttaa ttggtgttta
    21481 actaatgatt aaaaaggaga atataatgac taaacgcgtc ttaatcagcg tctcagacaa
    21541 agcgggcatt gttgaatttg cccaagaact caaaaaactt ggttgggaga ttatctcaac
    21601 aggtggaact aaggttgccc ttgataatgc tggggtggat accattgcta tcgatgatgt
    21661 gactggtttc ccagaaatga tggacggtcg tgtgaagacc ctccacccaa atatccacgg
    21721 agggcttctc gctcgtcgtg acttggatag ccacttggaa gcggctaagg acaacaagat
    21781 tgagctcatt gaccttgtgg tggtcaacct ttacccattt aaggaaacta tccttaaacc
    21841 agatgtgact tatgctgatg cagttgaaaa tatcgatatt ggtgggccgt ctatgcttcg
    21901 ttcagcagcg aaaaatcatg ccagtgttac agttgtggta gatcctgctg actacgctgt
    21961 ggttttggac gaattggcag caaacggcga aacctcttat gaaactcgcc aacgtttagc
    22021 agccaaagta tttcgtcaca cagcggctta tgacgccttg attgcagaat acttcacagc
    22081 tcaagtgggt gaaagcaagc ctgaaaaact cactttgact tatgacctca agcaaccaat
    22141 gcgttacggt gagaatcctc aacaagacgc ggacttttac cagaaagctt tgcctacaga
    22201 ttactctatt gcttcagcca aacagctcaa cgggaaagaa ttgtcattta ataatatccg
    22261 tgatgcagat gctgctatcc gtatcatccg tgacttcaaa gatagtccaa ccgttgtggc
    22321 tctcaaacac atgaatccat gtggaattgg tcaagctgat gacatcgaga ctgcttggga
    22381 ctacgcttat gagtctgacc cagtgtctat ctttggtgga attgtcgtcc tcaaccgtga
    22441 ggtggatgct gcgacagctg agaagatgca cggcgttttc ctcgaaatca tcattgcacc
    22501 aagctatacg gatgaagcgc tagccatttt gatcaataaa aagaaaaact tgcgtatcct
    22561 tgccttgcca tttaatgctc aagaggctag cgaagtggaa gcagaataca caggtgtagt
    22621 cggtggactt ctcgtgcaaa atcaagacgt ggtcaaggaa agcccagctg actggcaagt
    22681 ggtgaccaaa cgtcagccaa ccgagacaga agcgactgct cttgagttcg cttggaaggc
    22741 tatcaagtac gtcaaatcaa atggtattat cgtgaccaac gaccacatga cacttggtgt
    22801 tggtccaggt caaaccaacc gtgtggcttc tgttcgcctt gccattgacc aagccaaaga
    22861 tcgtctggac ggggcggtcc ttgcttcaga tgccttcttc ccatttgcgg ataacgtgga
    22921 agaaatcgcc aaagcaggaa ttaaggccat catccagccc ggtggctctg tccgtgacca
    22981 agaatccatc gaagcagcga ataaatacgg cttgactatg gtctttacag gtgtgagaca
    23041 ttttagacat taagaagata aaagggaaga aaacagtttc tttccttttt tggcttaaaa
    23101 tgctaactga aacaagatta aaacgaactt ttttgatata atgttggtaa ataattcgca
    23161 aaagaggttg aggaatgaaa ctgcttgttg tcggttctgg tggtcgtgag catgcgattg
    23221 ctaaaaagtt acttgaatca aaagacgtgg aaaaagtctt tgtagctcct gggaatgatg
    23281 ggatgactct ggatggtttg gaattggtaa atatctctat ttccgaacat tctaaattga
    23341 ttgacttcgc aaagaccaat gatgttgctt ggacctttat cggtccagat gatgcccttg
    23401 ctgctggtat cgtggatgat tttaaccaag ctgggcttaa ggcctttggt ccgactagga
    23461 ctgcagcgga gctggagtgg tccaaggatt ttgccaagga aatcatggtc aaatatggtg
    23521 tttcgacagc agcctatggc acattttcag atttcgagga agcaaaggcc tatatcgaaa
    23581 agcatggtgc gcctatcgta gtcaaggcgg atggcttggc gcttgggaag ggtgtcgtcg
    23641 ttgctgagac ggttgagcaa gcggtcgaag ccgctcatga gatgcttttg gacaataaat
    23701 ttggtgactc aggtgcgcgc gtggttattg aggaattcct tgaaggagag gaattttcac
    23761 tctttgcctt tgttaatggt gataagttct acatcatgcc aacggctcag gaccacaaac
    23821 gtgcctacga tggcgacaaa gggcctaaca cgggtggtat gggtgcctat gcgccagttc
    23881 cacacttacc acagagtgta gttgatacag cggttgacac cattgtcaag ccagttctag
    23941 aagggatgat taaagaaggt cgcccttatc tgggagttct ttacgcaggg cttatcctga
    24001 cagctgatgg accgaaagtc attgagttca acgctcggtt cggagatcca gaaactcaga
    24061 ttatcttgcc tcgcttgacc tctgactttg ctcaaaatat cacagatatc ctggatagca
    24121 aggagccaaa tatcatgtgg acggacaagg gtgtgactct gggtgtggtt gtcgcatcca
    24181 agggctaccc gctagactat gaaaggggcg ttgagttgcc agccaagaca gaaggcgatg
    24241 tcatcaccta ctatgcaggg gctaagtttg cggaaaatag cagagcactg ctctcaaacg
    24301 gcggacgagt ttatatgctg gttaccacag tagccaccgt caaagaagcc caagccagca
    24361 tctaccaaga actatcccaa caaaaaatag aaggactctt ctaccgaaca gatatcggaa
    24421 gcaaggcaag taagtaaaga tataagaata acgcgacgca gtcgccaaac acgataatgg
    24481 tcgtcgtggt gaaaagacca gaacagtgaa tgttctggtc agggggaaac tttgagacct
    24541 taggctcaaa gtttaggaat gaaaccgaag gtttgcttcc gcctccatca cctaagacca
    24601 ttatcaaaaa gaaaaataaa aattcacaaa atacgttaat ggtcgtatgg tttgcgagcg
    24661 ttagcgagct aatatagaat aatcaccgcc gttgtgaaag aacgattgga tgataatcca
    24721 atcgttcagg gaaattggaa gaccttgggt ttccaattta ggcatgagac acctttggtg
    24781 gctgctgccg tccctcacaa gctaaggtga ttgttgaaaa agaggaaaaa ggagaagaaa
    24841 tgaaaccagt aatttccatc atcatgggct caaaatccga ctgggcaacc atgcaaaaaa
    24901 cagcagaagt cctagaccgc ttcggtgtag cctacgaaaa gaaagttgtt tccgcacacc
    24961 gtacaccaga cctcatgttc aaacatgcag aagaagcccg tagtcgtggc atcaagatca
    25021 tcatcgcagg tgctggtggc gcagcgcatt tgccaggcat ggtagctgcc aaaacaaccc
    25081 ttccagtcat tggtgtgcca gtcaagtctc gtgctcttag tggagtggat tcactctatt
    25141 ctatcgttca gatgccgggt ggggtgcctg ttgcgaccat ggctatcggt gaagctggag
    25201 cgactaacgc agctctcttt gccctccgta tcctctctgt agaagataag tccattgcgg
    25261 atgcacttgc caactttgct gaagaacaag gaaaaatcac agaggagtcg tcaaatgagc
    25321 tcatctaaaa caatcggaat tatcggtggc ggtcaactgg gtcagatgat ggccatttct
    25381 gctatctaca tgggccacaa ggttatcgcg ctggatcctg cggcggattg cccggcctct
    25441 cgcgtggcgg aaatcattgt ggcaccttat aacgatgtgg acgccctccg tcagttggca
    25501 gaccgttgcg atgtcctcac ttacgagttt gaaaatgtcg acgctgacgg tttggatgcc
    25561 gttatcaagg atggacaact ccctcaagga acagatctgc tccgcatttc gcaaaatcgt
    25621 atttttgaaa aggacttttt gtcaaacaag gctcaagtca ctgtggcacc ctacaaggtc
    25681 gtgacttcta gcctagactt ggcagatatc gacttgtcga aaaactatgt cctcaagact
    25741 gcgactggtg gctacgatgg tcatggacaa aaggttattc gttcagaagt agacttggaa
    25801 gcagcctatg cgctagcaga ctcagcagac tcagcagact gcgtcttgga agaatttgtc
    25861 aactttgacc ttgagatttc tgtcatcgtg tcaggaaatg gcaaggaggt gacgtttttc
    25921 ccagttcagg aaaatatcca ccgcaacaat atcctgtcta agaccatcgt accagcccgc
    25981 atttctgaaa gtctagtaga caaggctaaa gctatggcag tgcgaatcgc agaacaactc
    26041 aacttgtctg gaactctctg tgtggaaatg tttgcgactg atgatgacgt tattgtcaat
    26101 gaaatcgccc cacgaccaca taactctggg cactattcta ttgaagcctg tgatttctct
    26161 cagtttgaca cccatattct cggtgttctc ggagcaccat taccagtcat caaactccat
    26221 gcgccagccg ttatgcttaa tgtcctcggt cagcatgtcg aggctgctga gcaatatgtg
    26281 acagaaaatt caagcgccca cctccacatg tatggtaaaa tagaagcgaa gcacaaccgc
    26341 aagatgggac atgtgacctt gtttagtgat gtaccggata gtgtggatga gcttggggaa
    26401 gggattgatt tttaggacaa gtctatgata caaattatcg ttaatacatt tattgaaaag
    26461 gataagactg gagcagttgt tgaagtgttg tatgccagtg ctgaccaaga taaggtacaa
    26521 gctaaatatg aagaactagc tgcacaatac cccgaaaatt atttagctat ctatgatgta
    26581 ccgctggata cggatttgaa tacactagat cattacccgt ctgtgtttat tgaaaaagag
    26641 gagtttgagt agaattcttg gtttacctag atagcttatt cccaacagct taagaagaaa
    26701 ggaaaaatta acacatgatc aaccgttact ctcgccctga gatggcgaat atttggagtg
    26761 aagaaaataa ataccgtgct tggcttgagg tggaaatcct ctctgacgag gcatgggctg
    26821 agttggggga aatccctaag gaagatgtgg ctttgattcg caagaaggcg gactttgaca
    26881 tcgaccgtat tttggaaatt gagcaggaga cgcgccacga tgtggtggct ttcacgcgtg
    26941 cggtttctga gactcttggt gaagagcgca agtgggttca ctatgggtta acttctaccg
    27001 acgtggtgga tactgcttat ggttacctct acaagcaggc caacgacatc atccgtcgtg
    27061 accttgaaaa cttcactaat atcatcgctg acaaggccaa ggagcacaag ttcaccatca
    27121 tgatggggcg tactcatggt gtgcacgctg agccgacaac ctttggtctt aaattagcaa
    27181 cttggtacag cgaaatgaaa cgcaatatcg agcgcttcga gcatgcggct gctggtgtag
    27241 aagctggtaa gatttctggt gcggttggga actttgccaa tatcccacca tttgtagagg
    27301 agtatgtctg cgataaactt ggcatccgtg cccaagaaat ctctacacaa gtccttcctc
    27361 gtgaccttca cgctgagtac tttgcggttc ttgccagcat tgcgacttca atcgaacgta
    27421 tggcgactga gattcgtggt ctacaaaaat ctgagcaacg cgaagtagaa gagttctttg
    27481 ctaaagggca aaaagggtct tcagcaatgc ctcacaaacg caacccaatc ggttctgaaa
    27541 atatgactgg tctggcgcgt gtcattcgtg gtcacatgat tacggcttat gaaaacgtcg
    27601 ctctctggca cgaacgcgat atttctcact catcagctga gcgtatcatc acaccagata
    27661 cgaccatttt gattgactac atgctcaacc gttttggaaa tatcgtcaag aacttgacag
    27721 tcttcccaga aaatatgatc cgaaacatga actcgacttt tggtcttatc tttagccaac
    27781 gggctatgtt gacattgatt gaaaaaggca tgacccgtga gcaagcctat gacttggtgc
    27841 aaccaaaaac agcctactct tgggacaacc aagtagactt taaaccactt cttgaggcag
    27901 attcagaagt aacatcacgt ctcacacaag aagaaatcga tgaaatcttc aacccagttt
    27961 attacaccaa acgagtggat gatatctttg aacgtcttgg actaggtgat taattaaaaa
    28021 ataaacagcg agcttcaatc tcgctgttta ttttttatcg aaaagactta gtcttctttt
    28081 cttttagtga gtccataggc tgctagtgtg gccatgagtc ctgcgactac tagtcctgca
    28141 gaatcgtgag ttcctgtttc aggaagtttt ttctctatta ccacaggagc tggatcttga
    28201 ggaagagctt tgctttcctc agcaggagct ggttggctta ggatttctag ttttggtttt
    28261 tcttcagcaa tagcggcttg tccgttttca tcgcctacat gtgttaccat agttccgact
    28321 tcgactattt gagtaacggc ttcctgtgct acgacactat ttacaagtgt tttcacttcc
    28381 ttaccatcgg cagaagtgct cacagagtag aagttgctac gatgtccatt gacaccctta
    28441 gtaatgactt gtgtttttcc tttgagtaag agtggatttt cacgagtcac tgtggtaaat
    28501 ggaatttctt cttcttggat atccagtcta ggttttacct cagtagttgg tgcaagacca
    28561 ctttcatcac ccttgtgagt tacaggagcg ccaacttcaa ccacttggtt tataacttct
    28621 ttggttacct ggctatcaag gactgtttct gttgtttttc cattttcagt gagtacagag
    28681 atgtaatgag ttcgttcacc tttgactcct gctgtgataa tattttcctg accagctggg
    28741 aggttaggat tttctttctt gataacttca aatggaattt cttcagttct tgtgatgagt
    28801 tctggtctgg tttcaacatt ggcagccact tcattttcat ccaggcttcc tgaatgagtt
    28861 gcagctggtt tgaggccttg aagagcggct tttaggttgg ctacaagtat gtcaagctca
    28921 gcttgtttat tacggttgag gttgtaattt agagctgttt tagctgcgtc aagggcctca
    28981 agactttctt tactatatcc ttctaagttt gtaggaattt tagctaattc ttcgcggaga
    29041 gcattataat tagcacggaa gtagtctttg ttgtggtctg caaaggcagt catgagttca
    29101 aagatttcct cttccttgta ctcagcgctt ggtctatctg cccagattga aagcatactt
    29161 ccgactgttg gaagatctac ttcaggatat ttggtagaag ctagttgatt gaatggtgtt
    29221 tttccagtat tctcaatagc tttcttgagg aaaccaccac catcttctgg tttttgacca
    29281 agaatgtagt accagtcacc gttggtattc aagaatttat agcctttgct tgctaggtat
    29341 tgaggtgatg cgaggttata tccccaccag cctttagacc agtaagaaat caagacatct
    29401 ttgtcaaact gaacatcgtc cttgtcttca tagtagaagc catcgttgaa ggccattggt
    29461 tgaagccctc tttctttggc catagctgcg agggtgttgg catattcggc aaatttgcca
    29521 tagagttgat accacttgag gtagtaccag ccttgggcac tagtcgcatc gttggcgtat
    29581 tcgtcagtac caaagttgaa aatctttgtt ttacctgcaa agaagtccat gtatttaccg
    29641 atgagggctt ttacaaagtt catcgcttct tcgtttttca agtccatagt tgtttttgaa
    29701 actttatcaa agtgggcttg aggattttta atacctaatt tttccatggc aaccagcata
    29761 gcatccatgt gacctggact gttaatagct gggatgagac cgatgtcctt agatttagcg
    29821 tattcaatta gctctgtcac ttctgcctgt gttagtgcag taccgtttgg atcgtcgtag
    29881 taagctttag ttccttcgat aatagctttt ttaacgtcat cactagcata ggtttttccg
    29941 ttggcagtaa tggtcatatc atcgagtaga aagcgaagtc cgtcatttcc tagaaggaga
    30001 tggacatcag aatatccgag ctcactggcc ttgtctacga tgcgtttgag ctggttcaga
    30061 gtaaagtatt tgcgtccagc atcgattgag attaccttgt ttttggcaag tttttcaacc
    30121 tcacgtttag cttcttcttc tttttgagct tcaggcgtga gggtcaagtt gttgacagtt
    30181 tcttgaagtt tagcaatggc ttgatcaatc gtatcttgtt gggcacggct aaggttgcta
    30241 tcgagagagc gaatagcttt ttcagcttct tttacggccg tgacgctttc tgcagtataa
    30301 cggttcaggt cttttggtac ctcgttaagt gcttgctctg cagattcata atcagctgcg
    30361 aagtattcag cgttggcatt tgcaaaatga cgcatgagtt tgaagaggcg tgatggtgaa
    30421 taacgtgcag atggagtgtc agcccaagca gctaccatac caccgatgat tgggatatca
    30481 gctccttctg tttttggtac agaagtgatt ggtgtgtttt taataccatt gagcccctga
    30541 tcgagattgt accagccttg gccatcagcg tttcgtccaa gaacgtagta ccaagcatca
    30601 ttggtattaa ggatttggtg acctttttca gctagtagtt tagaagaagc gacatcgtag
    30661 cctccccaac caccagtcca catagaaacg atgatgtctt tgtcaaaact accaaagctt
    30721 gtgtcgctat tgtagtagat accgtcgtta aaggccattg gtttgagacc gtgcgatttt
    30781 acaatacgag cgaggtcatt ggcgtaggca ataaattttt catagccttt tacagggtag
    30841 ccttcgtttg gatagtattt atcagcttga agcacactcc aacctttagc atctgtcgca
    30901 tcattggcat attcatcaag tccgatgttg aagatttcag tctttttcgc gaaataagca
    30961 gcatacttgt cgataagggc ttttgtaaaa gcgacagctt gttcgttgtc aagatcgaca
    31021 gtacgggctg attccttccc aaaatagcta aagttagggt tttggattcc caattctttc
    31081 atggcattga gaatcgcatc catgtgacca ggactattta ctgtcggaat gagaccgata
    31141 cctttatctt tggcatagtt aatcagatct gtcatttgac tttctgttaa gtgattgccg
    31201 tttggatcgt tgtaataatc atttgtacct ttttcaatgg cgcgtttgac atcgtcactg
    31261 gcataggtct tgccgttagc tgtgatgctc atatcgtcca acatgaaacg gagtccatca
    31321 tttccgacta ataggtgtaa atcagtgtag ccataatgtt tcgctttatc gatgattttc
    31381 ttgagctgtt ctggtgagaa atatttacgt ccagcatcaa tagaaacaat tttctttttc
    31441 gctagttttt catttacagt tgcagcacgt tcctttcctg cctctgttgc cggtttgtca
    31501 gcctctgctt tcgcttcatc ttttttagct ggtttatcct tgtcagtctt gtctgtattt
    31561 gactctttag aatcaacctc tttcgcttct tcctttttag ggctagcttc ttctgccttt
    31621 ttattagcag tttctttttc agcagaagtt ggagttacca cttctgcttt atcactagga
    31681 gttgaactaa cttcctcttg tggtttttct tctgtttttg gaagactagc taccttatca
    31741 gtagctggag tttctgtttc tacagttttt ggagcttctg gttgaagctc tgctttaggt
    31801 gtttcctcag tccgattttc ggatgattga ggggaatcag aaaccgtatg gatggtcggt
    31861 tggttttctg tagtagtagg agtaactcca tcggctgcaa cagtctgtgc ttggaaggca
    31921 aatccaatta gaacagaagc tgctcctaca gcgtatttac gaatagaaaa acgctgttgt
    31981 ttttcatgtt tcattgcaaa acctcctgat tgcattgtta tattgatagc gattatataa
    32041 atcaacgccc ttattttatt tcttatatta acgagagtca agaggagatg acaaaaaact
    32101 ataataagta taaaaaaata taaaatttaa acttaagatt tcagattggt cggaaaaaat
    32161 gcatatatat atctaatata atttttggtt ctatttctat aaaatattcc acaaattata
    32221 gaatcttcca aaaataggta agcgctacct ttttggtgtg gtataataag catagaaaaa
    32281 gcccgagcga ttaggctcag gctttcttct tagtgatcac ggtcacatga gatgaattta
    32341 atcttgtagt aatcagatcg tttgtaagtt tcactgtatt ctaaaacttg gccagttgat
    32401 tcgagtttgg tgattttagt ttgtaggaca gtagggaatt gttcatcgac tccgaggact
    32461 gaagccgcat gttctggagt tggaaagact atttcgttga tttcttcaaa gtgttcatca
    32521 ttcatgtgaa tgtggtagtc taacttgaaa cgattataga tagaactata gtattcaagg
    32581 tttggataat ttgcgttgat atattgttct gggatgtagg atgtatggta gatataaacg
    32641 acaccgtttg attcgcggat acgttcaatc ttgtagtaga attgatcgcc acgtagaccc
    32701 aatttttcca agtaaacaag cttgtttccg cgttcaattg aaagaacagt taccttatca
    32761 tctttagcat tgaagagttc aatatctgaa aactctacaa gcttgtgttt gcgtgcacgt
    32821 gaaacgaagg ttccttttcc ttgttggcgg acaatatagc catctttggc aaggtcgttt
    32881 aaggcgcgaa caactgtgat agagctgaca tcgtacattg aaatgagttc tgcttcagtg
    32941 taaaatttat ctccactgct aaactgccca gagatgattt tattttttaa ttcgtctttt
    33001 atgtattgat atttgggaat tgccatattt ttacctctat tttccttctc catagaaaat
    33061 tttaccataa aagcgaaaaa aatagtagtc ttttgaataa aaaattagaa taatagtttg
    33121 aaaaattaag cgatataggg attgctcata ttttatcaat gtattctata caaaattatt
    33181 ttatgtccta tattccgaat ttaaagagcg tttgaaatgg gtctaaaaat gtttgaaact
    33241 aattgaatgt gtgtataata gtaaaaatgc agtaaatatc ccgacaattt ctattgacaa
    33301 ttcaaacaga ttggtttata attaatataa caacaaatga aagcgcaaac tttcgtggtc
    33361 ggaaggtagt tttatgacac gatttgagat acgagatgat ttctatctcg atggaaaatc
    33421 atttaagatt ttatctggtg ccattcatta ttttagggtt cctccagagg attggtatca
    33481 ttcgctctat aacttgaagg ctcttggttt taatacggta gagacttatg ttgcttggaa
    33541 tttacacgag cctcgtgaag gtgagtttca ttttgaaggt gatctggatt tagagaaatt
    33601 tctccaaata gcgcaggatt tgggtctcta cgcaattgtg cgtccgtctc catttatctg
    33661 tgcggaatgg gaattcggtg gcttaccagc ttggctcttg accaagaaca tgcgaattcg
    33721 ctcatccgac ccagcatata tcgaggcagt tggtcgctac tatgatcagt tattgccaag
    33781 actggtgcct cgtttgttgg acaatggtgg caatattctc atgatgcagg ttgaaaatga
    33841 gtatggttct tacggagaag ataaggctta cctgagagcg attcgacagc taatggaaga
    33901 gtgtggcgta acctgtcccc tctttacatc agatggtccg tggcgagcta ctctgaaagc
    33961 tggaacctta attgaagagg acctctttgt aacaggaaac tttggttcta aggcacctta
    34021 caacttttcg cagatgcagg aattctttga tgaacatggt aagaaatggc cactcatgtg
    34081 tatggagttc tgggatggtt ggttcaatcg ctggaaagaa ccgattatca cacggaatcc
    34141 taaggaattg gcagatgcag ttcgagaggt tttggaacaa ggctctatca atctttacat
    34201 gttccacggt ggtacaaact ttggtttcat gaatggttgc tcagctcgag gaactttgga
    34261 cctgccacaa gttacgtctt atgattacga tgcccttctg gatgaagaag gaaatccaac
    34321 tgctaaatat cttgcagtca agaagatgat ggcaacacat ttttcagagt atccgcagtt
    34381 ggaaccactc tacaaagaga gtatggagtt ggatgctatt ccactagttg aaaaagtttc
    34441 tttgtttgaa accttagata gcttgtcaag tcctgtagaa agtctctatc ctcaaaagat
    34501 ggaggagctg ggacaaagtt atggctacct actttatcga acagaaacaa actgggatgc
    34561 agaagaagaa agacttcgta tcattgatgg tcgagatagg gcccagctgt atgtcgatgg
    34621 tcagtgggtt aaaactcaat atcagacaga gattggggaa gatatttttt atcaaggtaa
    34681 aaagaaaggg ctatctaggt tagatatctt gatagaaaat atggggcgtg tcaactatgg
    34741 gcataagttc ttagcggata cgcaacgtaa gggaattcgg acaggggtct gtaaggatct
    34801 gcatttctta ctaaactgga aacactatcc actcccacta gacaatcctg agaaaattga
    34861 tttttcaaaa ggatggactc aaggacaacc agccttttac gcttatgact ttacagtcga
    34921 agagccaaaa gatacttacc tagacttgtc tgagtttggt aagggggttg cctttgtcaa
    34981 tgggcagaat ctaggacgtt tttggaacgt tggcccaact ctctcacttt atatccctca
    35041 tagctatctc aaggaaggtg ccaaccgcat cattatcttt gaaacagaag gtcaatataa
    35101 agaagagatt catttaactc gtaaacctac actaaaacat ataaaggggg aaaacttatg
    35161 acaattgtag gatgccgtat tgatggacgt ttgatccacg gacaagtagc caatctttgg
    35221 gctggaaaac taaatgtttc acgcattatg gttgtagacg acgaagttgt caacaacgat
    35281 attgaaaaga gtggtttgaa acttgcgaca ccaccaggtg tgaaattgag tattttgcca
    35341 gttgagaaag ctgcagccaa tattcttgct ggcaaatacg atagccaacg tctctttatc
    35401 gtggctcgta aaccagaccg cttccttggt ttggtagaag caggtgtacc acttgaaacc
    35461 cttaatgttg ggaatatgtc tcaaacacca gaaactcgtt ctattacacg ttctatcaac
    35521 gtagtagaca aggatgtgga agacttccac aaactggcag aaaaaggtgt taaacttact
    35581 gctcagatgg ttccaaatga tccaatttca gactttttga gcttattaaa ataggaaaaa
    35641 aatttttagg aggtcattgt tatgatacaa tggtggcaaa ttttacttct cactttgtac
    35701 tcagcttatc aaatctgtga tgagttgacg atcgtttcat ctgcaggttc ccctgtattt
    35761 gctggtttca ttactggttt aatcatggga gatgtgacta ctggtttact tatcggtggt
    35821 aacttgcaac tgttcgttct tggggttggt accttcggtg gtgcttctcg tatcgacgca
    35881 acttctggtg cggttcttgc gacagccttc tctgtttcac aaggaattga tgcaccgctt
    35941 gccattacta caatcgctgt accagtagca gctctcttga cttacttcga cgttcttggt
    36001 cgtatgacta ctaccttctt cgctcaccgt gtggatgctg caatcgaacg ctttgactat
    36061 aaaggtattg aacgcaacta cttgcttggt gcgattccgt gggctctatc tcgtgccctt
    36121 ccagtcttct ttgcccttgc ttttggtggt gcctttgtac aatcagtagt agacttcgtt
    36181 gaagcctaca aatgggttgc atatggcttg acacttgcag gacgtatgct tccaggtctt
    36241 ggatttgcaa tcttgcttcg ttaccttcca gttaaacgta accttcacta ccttgctatg
    36301 ggatttggtt tgacagctat gttgactgtt ctttactcat atgtaacagg tcttggtggc
    36361 gctgttgctg gtatcgtagg tactcttcct gctgaagttg ctgaaaaaat tggtttcgtg
    36421 aacaacttca aaggtttgtc tatgattggt atttctatcg taggtatttt ccttgcagtg
    36481 cttcacttca aaaatagcca aaaagtagct gtagcagcac cttctacacc atcagaaagt
    36541 ggggaaatcg aagatgacga attctaatta caaacttaca aaagaagatt ttaatcaaat
    36601 caacaaacgt agcttgttta ctttccaatt aggttggaac tacgaacgta tgcaagcttc
    36661 tggttacctt tacatgatct tgcctcagtt gcgtaaaatg tatggtgatg gaactcctga
    36721 attgaaagaa atgatgaaag ttcatactca attcttcaat acttcaccat tcttccatac
    36781 cattatcgct ggttttgacc ttgccatgga agaaaaagat ggtgtaggtt caaaagacgc
    36841 cgttaacggt atcaagacag gtttgatggg accattcgct cctcttgggg atacaatctt
    36901 tgcttcactt gtacctgcta tcatggggtc agtcgcagca actatggcta tcgctggcca
    36961 accttggggg atcttccttt ggattgcagt tgcagtagcg tatgacatct tccgttggaa
    37021 acagttggaa tttgcttaca aagaaggggt taaccttatc aacaacatgc aaagtacctt
    37081 gacagctttg attgacgctg catctgtact tggtgtcttc atgatgggtg ctcttgtagc
    37141 aacagtgatt aactttgaaa tttcttacaa gttgccaatc ggtgaaaaga tgattgattt
    37201 ccaagacatc ttgaatcaaa tcttcccacg tttgcttcca gcaatcttta ctgcctttat
    37261 cttctggttg cttggtaaga aaggtatgaa ctctactaaa gctatcggta ttattatcgt
    37321 acttgctttg gctctttctg cccttggtca ctttgcactt ggaatgtaat tccttatgac
    37381 taaatcatta attttggtga gccatggtcg cttctgtgag gagcttagag gtagcacaga
    37441 aatgattatg ggcccacaag acaacattta cacagtagct cttcttccag aagatggccc
    37501 agaagaattt actgctaaat ttgaagctgt tattggagga ttggatgatt tcctagtctt
    37561 tgcggatctt ctcggtggga caccttgtaa tgtggtgagt cgcttgatca tggaaggtcg
    37621 tgatattgac ctttacgcag ggatgaatct tccaatggtg attgaattta tcaatgcgag
    37681 ccttacaggc gcagatgcgg actacaagag ccgtgctgca gaaagcattg tgaaagttaa
    37741 tgacctgtta gcgggcttcg atgatgacga agatgaataa tactcttcga aaatctcttc
    37801 aaactacgtc aacgtcgcct tgccgtaggt atatgttact gacttcgtca gtcttatccg
    37861 gcaacctcaa aacggtgttt tgagctgact tcgtcagttc tatctgcaac ctcaaagcag
    37921 tgctttgagc agcctgcggc tagtttccta ttttagttgg aactcgattc aattcatgtg
    37981 acaacgtgaa aatcgttaga gcattttata tagaatatac atgggaatgg agcttactcc
    38041 cattcccata tttaatagaa aaagaggaac tcaatgctac attatacaaa agaagacttg
    38101 ctcgaattgg gtgcagaaat cactacgcgt gaaatctacc aacagcctga tgtatggaga
    38161 gaagcttttg aattttatca agcaaaacgt gaagaaattg cagccttcct acaagaaatc
    38221 gctgataaac atgactatat taaggttatc ttgacaggtg ctgggacttc tgcttatgtg
    38281 ggagatacct tgctacctta ctttaaggaa gtctatgacg aacgcaaatg gaatttcaat
    38341 gctattgcga caacagatat cgttgccaat ccagcaacct atttgaaaaa agatgtggca
    38401 actgtccttg tgtcttttgc tcgtagtggg aactcgcctg aaagtgtggc gactgttgat
    38461 ttggccaaat ccttggtgga tgagctttat caagtgacga ttacttgtgc agcagatggt
    38521 aaattggctc ttcaagctca cggtgatgac cgtaatctct tgctcttgca accagctgtc
    38581 tctaatgatg ctggatttgc catgacttct agctttacgt ctatgatgtt gacagctctc
    38641 ttggtctttg atcctacaga atttgctgtt aagtctgaac gttttgaagt tgtatctagt
    38701 cttgcccgta aagttttaga caaggcagaa gatgtcaaag agctcgttga tttagacttt
    38761 aaccgtgtca tctatctagg cgctggtcct ttctttggac ttgctcatga agctcagctc
    38821 aagattttgg aattaactgc tggtcaagtt gcgaccatgt atgaaagccc agttggcttc
    38881 cgtcacggtc caaaatctct tatcaacgac aatacagttg ttttggtctt tggtacaacg
    38941 acggactaca ctcgtaagta cgacttggac ttggttcgtg aagttgctgg tgaccagatt
    39001 gctcgtcgtg ttgtgctttt gagtgatcaa gcttttggtc ttgaaaatgt caaagaagtg
    39061 gcccttggtt gtggcggtgt cttgaatgat atttaccgtg tcttccctta catcgtttat
    39121 gcccaactct ttgccctatt gacttcactc aaggtagaaa ataaaccaga tacaccgtct
    39181 cctacaggta cagtaaaccg tgtagtacaa ggtgtcataa ttcacgaata tcaaaagtaa
    39241 gacagtgttt atgaattctt gacaagagga tttgtaaatt atcagataaa ccatagattg
    39301 tcagtacgct ttctatggtt tgtttgcttg agagaaatag taaaaggaga acagaatgaa
    39361 agcatacaca gagcgtgtat ttggaaatgt tgagggtgag gatgtcttgg cctatcgatt
    39421 tgagacagac ggtggctacc aacttgaggt tatgacttat ggtgcgacta tcttgcgcta
    39481 tgtcgcacct gacaaggctg gaaattttgc caatgttatc ttgggatttg atgactttga
    39541 tagttatgta ggcaatagtc ccaagcatgg agcaagtgta ggtcctgtag cgggtcgtat
    39601 tgcaggtgcg acctttgagc tcaatggtaa gacctatgac cttgaggtta ataatgctag
    39661 caactgtaat cacagtggtt caactggttg ggattccagc ttgtttgaag ttgaagaagt
    39721 aagcgatcat ggcttgactc tctacacaga gcgtacagat gggacaggag ggttccctgg
    39781 aaatctcaag atttggatca gttatcactt ggaagaaact ggtgcctatg aaatcagcta
    39841 caaggtaacg accgatcagg atacgctggt caatccaacc aaccacagct atttcaactt
    39901 gtctggtgat ttcacgcaga cgattgaccg tcatgtcttc caactaaaca cagagggcat
    39961 ttactcaatc gctcctgacg gtgttcctgc caaaactcca gaagccaacc gtgatgtggt
    40021 caaacacatc tacaatggtg ccttgttgaa ggatatcttt gcagaagaag atgagcaaat
    40081 ccagctggca tcaggtttgg atcatccatt tgcccttcct gcaggccatg acaatgctgg
    40141 attcctttat gaccaaaatt caggtcgctt cctgcttttc aagacagaag ctccttgctt
    40201 tgtggtctac acagcaaact ttgtggatga aagtgtcatc ataggaggtc agccaatgct
    40261 acagcacaat gggattgctc ttgaagcgca agctttacca gatgccattc acagtgacct
    40321 taaaggccaa gtcattctta aagctggtca aaccttcacc agtaagacac gttatgaact
    40381 tgttgtgaaa taaaaaagct ggtcaaaaag tctttaaatt aaaataacgc atattgtcag
    40441 gtgatgaaaa gtttgataat atgcgtttta ttatgaaatg atttacttta tcttatcctg
    40501 aaatggtgtt atttttgagt tatctggctt gactttcttg atggaaatta tataatagtt
    40561 gtaataacaa taattacaac gagaaaagag gaccatttat gacctatgaa tacaagagtc
    40621 acatttattt ggcagagaca gttttaaatg taaaggattt ggccagtcaa acagcctttt
    40681 atcagcaagt tattggttta gaaatcttat ctcaaactga gacagagtcc attctaggcc
    40741 ttggtggaaa agtcttggta cagctgattc aagcacaaga gagcggagaa gtgagggaac
    40801 attatggtct ttaccatttg gccattctct tgcccacacg caaggctttg gctgatgtct
    40861 tgaaacatct gacagatttg caaattcctc ttgtcggcgg tgcagaccat ggttacagtg
    40921 aagctattta cttggaagat ttggagggaa atggcattga actctatcga gataagccag
    40981 tttccacatg ggatattcga gaagatggac gcattatcgg agtgacggag gctcttgcgg
    41041 cgcaggacat ttatgagttg ggggaaagag tagagccctt tatcctggca gaaggtacaa
    41101 gaatggggca tattcatctt tccgtcaagg atagtcgaaa gtccagccag ttttatcaaa
    41161 aggtgttagg gctagagaat aaattcagtg tgcctggcgc tagttggatt gcggctggag
    41221 attaccatca tcatttagca gttaacgaat ggagaggaaa aggtctggct tcgcgtaagc
    41281 aaggcttacc aggtttagcc tactatgtca tcgaagttgc acataaaaaa gaactgttaa
    41341 cgattgccca acgagcacaa gaagttgacg caccaatcaa atggatgaca tcgagcaaat
    41401 tggaaatcac agactcagat ggcatcgtga cccgtattcg tttagcaagg taaaattagg
    41461 aatttttaat aagttataag tattgctagt ttgctttttg aacggtcttt ggtaacagaa
    41521 ctgcgtgagc tggatgggtg agaattttga caaagaagct gattagagat ataatgaaga
    41581 aaaatcgagc aaggaaaaag aaatgacaaa ttcaaagtat attacttgtt tgaaacgttc
    41641 agagggccag ttgtgtggga ttcaaaagat gattgaagga gatcgtgact gtgctgatat
    41701 tgtgacgcaa ctgacagcag tgagatctag tgtagagcgc gtgattgaga tgataattac
    41761 cgaaaatctt actgaatgta tcaatcagct actagatgat tctgaagctc aaaaggaacg
    41821 cctagaaaag gctatccgat acttgattaa acggaaataa atgaatgttt tgagacgata
    41881 tgtgcaaagg tctattaact attagaatag tttaatgtga gtcaaaagaa gttgtaaaaa
    41941 atctttaaaa ttaaaaaaac gcatagtatc aggtgttgaa tgtactgacc cccaaaagtt
    42001 agattttttc tgtctaactt ttgggggtca gttcataaga accttggtaa tatgcgtttt
    42061 attatgtaga gacttatact cttcgaaaat ctcttcaaac cacatcagct tcaccttgcc
    42121 gtagatatgg ttactgactt cgtcagttct atccacaacc tcaaaacagt gttttgagct
    42181 gacttcgtca gttctatcca caaccttaaa acagtgtttt gagcagcctg cggctaactt
    42241 cctagtttgc actttgattt tcattgagta ttacttcatc ttttcctgaa attgagtttt
    42301 tgcccagctc ctcttgatta ttctacttga ccgggccaag cattcatacc accttctacg
    42361 ttggtaacgg tgaggccttg ggagctgaga aattggcagg tagatgcaga gcggactcct
    42421 ccttgacaaa tgacatagta ttcatggtca ggtttgagtt ctttgtagcc ttgctctaag
    42481 gtacttaatg gaagattttt ggcacctggt gcatgtcctg cttggaattc atgtgcttca
    42541 cggacatcga taagttctag attttcattt tggtattttc cataaaagtc agccatgctg
    42601 atactagttt ccatattcta ctccttctgg gttaaccatt ttgtatagtg aataagcgcc
    42661 gtcaaggttt tgggcggtaa atcctgcttg cttgaggata ggctctgcga tatagctgcg
    42721 caaaccactg tggcagctga cgatgtaggc ttgttttttg tccagttcat cagcttcctc
    42781 cttgacactt tgtcagtttt tgatacaata gtacaaaatt agaggaggca ggctatgatt
    42841 cagaaacatg cgattcctat tttagagttt gatgacaatc ctcaggcggt tatcatgccc
    42901 aatcacgagg ggctggactt gcagttgcca aagaagtgtg tttatgcatt tttaggtgag
    42961 gagattgacc gctatgcaag ggaagtaggg gcgaactgtg ttggcgaatt cgtttctgct
    43021 accaagacct atccagtcta tgttatcaac tacaagggtg aggaggtctg tctggctcag
    43081 gctcctgttg gctccgctcc agcagcccag tttatggatt ggttgattgg ctatggtgtg
    43141 gagcagatta tctctactgg gacctgtggt gtcctagctg atatagagga aaatgccttt
    43201 ctagtccctg ttcgcgcttt gcgagatgag ggagccagtt accactatgt ggcaccttct
    43261 cgttatatgg aaatgcagcc agaggctatt gctgctattg aggaagtttt ggaagacaga
    43321 gggattcctt atgaagaagt catgacctgg acgacagacg gtttttaccg agaaacggct
    43381 gaaaaggtgg cttatcgtaa ggaagaaggc tgtgctgttg tggagatgga gtgttctgct
    43441 cttgcggcag tagctcaatt gcgtggggtt ctctggggtg aattgttgtt cacagcagat
    43501 tctctagcgg acttggacca gtacgacagt cgtgactggg gctcggaagc ttttaataag
    43561 gcgctagaac tgagtttagc aagtgttcac cacctttagt tgtactggca aaggatttgt
    43621 tttatcataa aatgtctagc tcatactttt caaaaatatg tttaaacgag gtcaccttcc
    43681 tcttgtccta ggcatgttga ggttgggaaa aatctttaaa atcagaaaaa cgtatcatat
    43741 caggtgataa aaactttgat actatgcgtt ttatgttggt aagatttaga gtgagatgaa
    43801 atgatactct tcgaaaatct cttcaaaccg cgtcaacgtc gccttgccgt atagatgtta
    43861 ctgacttcgt cagttctatc tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtt
    43921 ctatccacaa cctcaaaaca gtgttttgag caacctgtga ctagctttct aatcgatgcc
    43981 ttggttctca ttgcctataa tcaaaaagag aaattttctc ctgaaaagca tatagagtag
    44041 ctggcgttaa aagctcctgt ctcgcttttt tgacctatag tcacatctat caagtattgt
    44101 tcttgcctaa gctatcaata aaaaggtggc attttttagg cttggtgtta gtagattttg
    44161 ccttatccta tctaagtcat ttcgaacttt ttatggtaca atggaaacat gttattcaaa
    44221 ttatctaagg aaaaaataga gctaggctta tctcgtttat cgccagcccg tcgtattttt
    44281 ttgagttttg ccttggtcat tttactaggc tctcttcttt tgagcttgcc ctttgtccaa
    44341 gttgaaagct cacgagcgac ttattttgat catcttttca ctgctgtctc tgcagtctgt
    44401 gtgacaggtc tctcaaccct tccagtagct caaacctata atatatgggg ccaaataatc
    44461 tgtttgcttt tgattcagat cggtggtcta gggctcatga cctttattgg ggttttctat
    44521 atccagagca agcaaaagct tagtcttcgt agccgtgcaa ctattcagga tagttttagt
    44581 tatggagaaa ctcgatcttt gagaaagttt gtctattcta tttttctcac gacctttttg
    44641 gttgagagct tgggagctat tttgcttagt tttcgcctta ttcctcaact tggctgggga
    44701 cgtggtcttt ttagttccat ttttctagcg atctcagcct tctgtaatgc cggttttgat
    44761 aatttaggga gcaccagttt atttgctttt cagaccgatt tactggtcaa tctggtgatt
    44821 gcaggcttga ttattacagg ctgccttggt tttatggtct ggtttgattt ggctggtcat
    44881 gtaggaagaa agaaaaaagg acgtctgcac tttcatacga agcttgtact attgttgact
    44941 ataggtttgt tgttatttgg aacggcaact actctctttc ttgagtggaa caatgctgga
    45001 acgattggca atctccctgt tgccgataag gttttagtta gcttttttca aacagtgacg
    45061 atgcgaacag ctggcttttc tacgatagat tatactcagg ctcatcctgt gactcttttg
    45121 atttatatct tacagatgtt tctaggtggg gcacctggag gaacagctgg gggactcaag
    45181 attacgacat tttttgtcct cttggtcttt gcacgaagtg agcttctagg cttgcctcat
    45241 gccaatgttg cgagacgaac gattgcgtcg cgaacggttc aaaaatcctt tagtgtcttt
    45301 attatctttt tgatgagctt cttgatagga ttgattctgc tagggataac agccaaaggc
    45361 aatcctccct ttatccacct catatttgaa accatttcag ctcttagtac agttggtgta
    45421 acggcaaatc tgactcctga ccttgggaaa ttggctctca gtgttatcat gctacttatg
    45481 tttatgggac gaattggtcc cttgaccttg tttgttagct tggcagatta ccatccagaa
    45541 aagaaagata tgattcacta tatgaaagca gatattagta ttggttaaga aaggaaagag
    45601 catgtcagat cgtacgattg gaattttggg cttgggaatt tttgggagca gtgtcctagc
    45661 tgccctagcc aagcaggata tgaatattat cgctattgat gaccacgcag agcgcatcaa
    45721 tcagtttgag ccagttttgg cgcgtggagt gattggtgac atcacagatg aagaattatt
    45781 gagatcagca gggattgata cctgcgatac cgttgtagtc gcgacaggtg aaaatctgga
    45841 gtcgagtgtg cttgcggtta tgcactgtaa gagtttgggg gtaccgactg ttattgctaa
    45901 ggtcaaaagt cagaccgcta agaaagtgct agaaaagatt ggagctgact cggttatctc
    45961 gccagagtat gaaatggggc agtctctagc acagaccatt cttttccata atagtgttga
    46021 tgtctttcag ttggataaaa atgtgtctat cgtggagatg aaaattcctc agtcttgggc
    46081 aggtcaaagt ctgagtaaat tagacctccg tggcaaatac aatctgaata ttttgggttt
    46141 ccgagagcag gaaaattccc cattggatgt tgaatttgga ccagatgacc tcttgaaagc
    46201 agatacctat attttggcag tcatcaacaa ccagtatttg gataccctag tagcattgaa
    46261 ttcgtaaaga gggatgaccc ctcttttttg atgcccaaga tggcaaatag agacagaagc
    46321 cccttgtctt ctagtaaaag ttcttcaaag gctggacttt atggtaaaat agaaggaagt
    46381 gacaagagag agtaatactc aatgaaaatc aaagatcaaa ctaggaaact agctgcgggc
    46441 tgctcaaaac actgttttga ggttgtggat agaactgacg aagtcagctc aaaacactgt
    46501 tttgaggttg cagatagaac tgacgaagtc agtaacatct atacggcaag gcgacgttga
    46561 cgcggtttga agagattttc gaagagtata agaaaaaatc agtcccctaa aggagcagat
    46621 tatgaagtta ttgtctatcg ccatttctag ctataatgca gcagcctatc ttcattactg
    46681 tgtggagtcg ctagtgattg gtggtgagca agttgggatt ttgattatca atgacgggtc
    46741 tcaggaccag actcaggaaa tcgctgagtg tttagctagc aagtatccta atatcgttag
    46801 agccatctat caggaaaata aaggccatgg cggtgtggtc aatcgcggct tggcagaggc
    46861 ttctgggcgc tattttaaag tagttgacag tgatgactgg tggatcctcg tgcctacttg
    46921 aaaattcttg aaaccttgca ggaacttgag agcaagggtc aagagatgga tgtctttgtg
    46981 accaattttg tctatgaaaa ggaaggtcag tctcgtaaga agagtatgag ttacgagtca
    47041 gtcttgcctg ttcggcagat ttttggctgg gaccaggtcg gaaatttctc caaaggccag
    47101 tatatcatga tgcactcgct gatttatcgg acagatttgt tgcgtgctag ccagttctaa
    47161 ctgcctgaac atacttttta tgtcgataat ctctttgtct ttacgcccct tcagcaggtc
    47221 aagaccatgt actatctgcc tgtcgatttc tatcgttact tgattgggcg tgaggaccag
    47281 tctgtcaatg agcaagtgat gattaagtgc attgaccagc aactcaaggt caatcgactc
    47341 ttggtagacc agcttgattt gtcccaagtg agtcatccca aaatgcgaga atatctgctg
    47401 aatcatattg aaatcacgac ggtgatttcc agtaccctgc tcaaccgatc tgaaacagcg
    47461 gagcatctgg caaaaaaacg ccaattgtgg acctatattc agcaggaaaa tccagaagtc
    47521 tttcaggcta ttcgtaagac catgttgagc cgtttgacca aacattctgt cttgccagat
    47581 cgcaaactgt ccaatgtcgt ctatcaaatc accaaatctg tttatggatt taattaatat
    47641 aagtgtttta taagagggat ttaagaaaaa ttttaacttt ttcttagtcc tttttaattt
    47701 caggagatta tactagagtc atcaaataaa gaaagactct aaggagaatc ctatgaaatt
    47761 caatccaaat caaagatata ctcgttggtc tattcgccgt ctcagtgtcg gtgttgcctc
    47821 agttgttgtg gctagtggct tctttgtcct agttggtcag ccaagttctg tacgtgccga
    47881 tgtggtcaat ccgaccccag gtcaagtctt acctgaagag acatcgggaa cgaaagaggg
    47941 tgacttatca gaaaaaccag gagacaccgt tctcactcaa gcgaaacctg agggcgttac
    48001 tggaaatacg aattcacttc cgacacctac agaaagaact gaagtgagcg aggaaacaaa
    48061 ctcttctagt ctggatacac tttttgaaaa agatgaagaa gctcaaaaaa atccagagct
    48121 aacagatgtc ttaaaagaaa ctgtagatac agctgatgtg gatgggacac aagcaagtcc
    48181 agcagaaact actcctgaac aagtaaaagg tggagtgaaa gaaaatacaa aagacagcat
    48241 cgatgttcct gctgcttatc ttgaaaaagc tgaagggaaa ggtcctttca ctgccggtgt
    48301 aaaccaagta attccttatg aactattcgc tggtgatggt atgttaactc gtctattact
    48361 aaaagcttcg gataatgctc cttggtctga caatggtact gctaaaaatc ctgctttacc
    48421 tcctcttgaa ggattaacaa aagggaaata cttctatgaa gtagacttaa atggcaatac
    48481 tgttggtaaa caaggtcaag ctttaattga tcaacttcga gctaatggta ctcaaactta
    48541 taaagctact gttaaagttt acggaaataa agacggtaaa gctgacttga ctaatctagt
    48601 tgctactaaa aatgtagaca tcaacatcaa tggattagtt gctaaagaaa ctgtcgaaaa
    48661 agctgttaaa gat
//
LOCUS       DAVKAU010000011        48087 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVKAU010000011 DAVKAU010000000
VERSION     DAVKAU010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48087
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.011"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(202..618)
                     /locus_tag="VWX48_000716"
     CDS             complement(202..618)
                     /locus_tag="VWX48_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171374.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEQTERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(630..1086)
                     /locus_tag="VWX48_000717"
                     /pseudo
     CDS             complement(630..1086)
                     /locus_tag="VWX48_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(1186..1398)
                     /locus_tag="VWX48_000718"
     CDS             complement(1186..1398)
                     /locus_tag="VWX48_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU9171375.1"
                     /translation="MIGESMEGYTPGELTSIELLEGRYARIEALSVEKHAEDLLAVYG
                     PDTPQEMWTYLFQEPVADMEELVSLL"
     gene            complement(1616..4117)
                     /locus_tag="VWX48_000719"
     CDS             complement(1616..4117)
                     /locus_tag="VWX48_000719"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU9171376.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            complement(4572..5660)
                     /locus_tag="VWX48_000720"
     CDS             complement(4572..5660)
                     /locus_tag="VWX48_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU9171377.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(5678..6346)
                     /locus_tag="VWX48_000721"
     CDS             complement(5678..6346)
                     /locus_tag="VWX48_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU9171378.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            complement(6365..8803)
                     /locus_tag="VWX48_000722"
     CDS             complement(6365..8803)
                     /locus_tag="VWX48_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU9171379.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(8954..10252)
                     /locus_tag="VWX48_000723"
     CDS             complement(8954..10252)
                     /locus_tag="VWX48_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9171380.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            complement(10269..10577)
                     /locus_tag="VWX48_000724"
     CDS             complement(10269..10577)
                     /locus_tag="VWX48_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9171381.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(10623..10943)
                     /locus_tag="VWX48_000725"
     CDS             complement(10623..10943)
                     /locus_tag="VWX48_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9171382.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            complement(11138..12118)
                     /locus_tag="VWX48_000726"
     CDS             complement(11138..12118)
                     /locus_tag="VWX48_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU9171383.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNVGIVKIEIENFDTNMFKLENYVKEKYSLESLEIIPNEFDDTPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            complement(12131..12877)
                     /locus_tag="VWX48_000727"
     CDS             complement(12131..12877)
                     /locus_tag="VWX48_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9171384.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYETKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRVIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     CQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAVSDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            12999..13775
                     /locus_tag="VWX48_000728"
     CDS             12999..13775
                     /locus_tag="VWX48_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU9171385.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            13850..14047
                     /locus_tag="VWX48_000729"
     CDS             13850..14047
                     /locus_tag="VWX48_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9171386.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKHLHISPKELKLLGRIVK"
     gene            14264..14860
                     /locus_tag="VWX48_000730"
                     /pseudo
     CDS             14264..14860
                     /locus_tag="VWX48_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            14936..15385
                     /locus_tag="VWX48_000731"
     CDS             14936..15385
                     /locus_tag="VWX48_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9171387.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADGEMTVGLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVL
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            15398..16489
                     /locus_tag="VWX48_000732"
     CDS             15398..16489
                     /locus_tag="VWX48_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171388.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLGLMQIAQYADRKPDKLSGGQQQRVTLACVLAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEELQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            16479..18124
                     /locus_tag="VWX48_000733"
                     /pseudo
     CDS             16479..18124
                     /locus_tag="VWX48_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(18227..18919)
                     /locus_tag="VWX48_000734"
     CDS             complement(18227..18919)
                     /locus_tag="VWX48_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9171389.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLISGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(19163..20500)
                     /locus_tag="VWX48_000735"
     CDS             complement(19163..20500)
                     /locus_tag="VWX48_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU9171390.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(20510..20776)
                     /locus_tag="VWX48_000736"
     CDS             complement(20510..20776)
                     /locus_tag="VWX48_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU9171391.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(21041..21427)
                     /gene="rplQ"
                     /locus_tag="VWX48_000737"
     CDS             complement(21041..21427)
                     /gene="rplQ"
                     /locus_tag="VWX48_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU9171392.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(21439..22374)
                     /locus_tag="VWX48_000738"
     CDS             complement(21439..22374)
                     /locus_tag="VWX48_000738"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU9171393.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(22417..22800)
                     /gene="rpsK"
                     /locus_tag="VWX48_000739"
     CDS             complement(22417..22800)
                     /gene="rpsK"
                     /locus_tag="VWX48_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU9171394.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(22818..23183)
                     /gene="rpsM"
                     /locus_tag="VWX48_000740"
     CDS             complement(22818..23183)
                     /gene="rpsM"
                     /locus_tag="VWX48_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU9171395.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(23201..23317)
                     /gene="rpmJ"
                     /locus_tag="VWX48_000741"
     CDS             complement(23201..23317)
                     /gene="rpmJ"
                     /locus_tag="VWX48_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU9171396.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(23342..23560)
                     /gene="infA"
                     /locus_tag="VWX48_000742"
     CDS             complement(23342..23560)
                     /gene="infA"
                     /locus_tag="VWX48_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU9171397.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(23677..24315)
                     /locus_tag="VWX48_000743"
     CDS             complement(23677..24315)
                     /locus_tag="VWX48_000743"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU9171398.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(24466..25776)
                     /gene="secY"
                     /locus_tag="VWX48_000744"
     CDS             complement(24466..25776)
                     /gene="secY"
                     /locus_tag="VWX48_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU9171399.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(25789..26229)
                     /gene="rplO"
                     /locus_tag="VWX48_000745"
     CDS             complement(25789..26229)
                     /gene="rplO"
                     /locus_tag="VWX48_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU9171400.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(26374..26598)
                     /gene="rpmD"
                     /locus_tag="VWX48_000746"
     CDS             complement(26374..26598)
                     /gene="rpmD"
                     /locus_tag="VWX48_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU9171401.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(26570..27064)
                     /gene="rpsE"
                     /locus_tag="VWX48_000747"
     CDS             complement(26570..27064)
                     /gene="rpsE"
                     /locus_tag="VWX48_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU9171402.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(27082..27438)
                     /gene="rplR"
                     /locus_tag="VWX48_000748"
     CDS             complement(27082..27438)
                     /gene="rplR"
                     /locus_tag="VWX48_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU9171403.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(27522..28058)
                     /gene="rplF"
                     /locus_tag="VWX48_000749"
     CDS             complement(27522..28058)
                     /gene="rplF"
                     /locus_tag="VWX48_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU9171404.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(28250..28648)
                     /gene="rpsH"
                     /locus_tag="VWX48_000750"
     CDS             complement(28250..28648)
                     /gene="rpsH"
                     /locus_tag="VWX48_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU9171405.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(28933..29202)
                     /gene="rpsN"
                     /locus_tag="VWX48_000751"
     CDS             complement(28933..29202)
                     /gene="rpsN"
                     /locus_tag="VWX48_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU9171406.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(29220..29762)
                     /gene="rplE"
                     /locus_tag="VWX48_000752"
     CDS             complement(29220..29762)
                     /gene="rplE"
                     /locus_tag="VWX48_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU9171407.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(29786..30091)
                     /gene="rplX"
                     /locus_tag="VWX48_000753"
     CDS             complement(29786..30091)
                     /gene="rplX"
                     /locus_tag="VWX48_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU9171408.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(30169..30537)
                     /gene="rplN"
                     /locus_tag="VWX48_000754"
     CDS             complement(30169..30537)
                     /gene="rplN"
                     /locus_tag="VWX48_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU9171409.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(30563..30823)
                     /gene="rpsQ"
                     /locus_tag="VWX48_000755"
     CDS             complement(30563..30823)
                     /gene="rpsQ"
                     /locus_tag="VWX48_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU9171410.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(30848..31054)
                     /locus_tag="VWX48_000756"
     CDS             complement(30848..31054)
                     /locus_tag="VWX48_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU9171411.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(31064..31477)
                     /gene="rplP"
                     /locus_tag="VWX48_000757"
     CDS             complement(31064..31477)
                     /gene="rplP"
                     /locus_tag="VWX48_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU9171412.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(31481..32134)
                     /gene="rpsC"
                     /locus_tag="VWX48_000758"
     CDS             complement(31481..32134)
                     /gene="rpsC"
                     /locus_tag="VWX48_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU9171413.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(32147..32491)
                     /gene="rplV"
                     /locus_tag="VWX48_000759"
     CDS             complement(32147..32491)
                     /gene="rplV"
                     /locus_tag="VWX48_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU9171414.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(32503..32784)
                     /gene="rpsS"
                     /locus_tag="VWX48_000760"
     CDS             complement(32503..32784)
                     /gene="rpsS"
                     /locus_tag="VWX48_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU9171415.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(32888..33721)
                     /gene="rplB"
                     /locus_tag="VWX48_000761"
     CDS             complement(32888..33721)
                     /gene="rplB"
                     /locus_tag="VWX48_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU9171416.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(33739..34035)
                     /locus_tag="VWX48_000762"
     CDS             complement(33739..34035)
                     /locus_tag="VWX48_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU9171417.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(34035..34658)
                     /gene="rplD"
                     /locus_tag="VWX48_000763"
     CDS             complement(34035..34658)
                     /gene="rplD"
                     /locus_tag="VWX48_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU9171418.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(34683..35309)
                     /gene="rplC"
                     /locus_tag="VWX48_000764"
     CDS             complement(34683..35309)
                     /gene="rplC"
                     /locus_tag="VWX48_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU9171419.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(35526..35834)
                     /gene="rpsJ"
                     /locus_tag="VWX48_000765"
     CDS             complement(35526..35834)
                     /gene="rpsJ"
                     /locus_tag="VWX48_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU9171420.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(36100..36717)
                     /locus_tag="VWX48_000766"
     CDS             complement(36100..36717)
                     /locus_tag="VWX48_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU9171421.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(36714..37304)
                     /gene="nrdG"
                     /locus_tag="VWX48_000767"
     CDS             complement(36714..37304)
                     /gene="nrdG"
                     /locus_tag="VWX48_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU9171422.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGILYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            complement(37297..37803)
                     /locus_tag="VWX48_000768"
     CDS             complement(37297..37803)
                     /locus_tag="VWX48_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171423.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            complement(37847..37987)
                     /locus_tag="VWX48_000769"
     CDS             complement(37847..37987)
                     /locus_tag="VWX48_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171424.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(37999..40206)
                     /gene="nrdD"
                     /locus_tag="VWX48_000770"
     CDS             complement(37999..40206)
                     /gene="nrdD"
                     /locus_tag="VWX48_000770"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU9171425.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(40326..41864)
                     /locus_tag="VWX48_000771"
     CDS             complement(40326..41864)
                     /locus_tag="VWX48_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9171426.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLQVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVEVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(41901..42044)
                     /locus_tag="VWX48_000772"
     CDS             complement(41901..42044)
                     /locus_tag="VWX48_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171427.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(42122..43654)
                     /gene="cls"
                     /locus_tag="VWX48_000773"
     CDS             complement(42122..43654)
                     /gene="cls"
                     /locus_tag="VWX48_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU9171428.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(43800..44318)
                     /locus_tag="VWX48_000774"
     CDS             complement(43800..44318)
                     /locus_tag="VWX48_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU9171429.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDG
                     DRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDM
                     DRDPSDQIVLTK"
     gene            complement(44315..45565)
                     /locus_tag="VWX48_000775"
     CDS             complement(44315..45565)
                     /locus_tag="VWX48_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9171430.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(45872..46177)
                     /locus_tag="VWX48_000776"
     CDS             complement(45872..46177)
                     /locus_tag="VWX48_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU9171431.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(46193..46612)
                     /gene="ruvX"
                     /locus_tag="VWX48_000777"
     CDS             complement(46193..46612)
                     /gene="ruvX"
                     /locus_tag="VWX48_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU9171432.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(46616..46882)
                     /locus_tag="VWX48_000778"
     CDS             complement(46616..46882)
                     /locus_tag="VWX48_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU9171433.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(46969..47538)
                     /locus_tag="VWX48_000779"
     CDS             complement(46969..47538)
                     /locus_tag="VWX48_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU9171434.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            complement(47604..48002)
                     /gene="spx"
                     /locus_tag="VWX48_000780"
     CDS             complement(47604..48002)
                     /gene="spx"
                     /locus_tag="VWX48_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU9171435.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT        14117 a        10471 c         8395 g        15104 t
ORIGIN      
        1 ttctaaaatt ttactatttt gcaaaaaatt tctatcacca gcacctcacc acgcaaaaaa
       61 gccacctgat tgggtggctt cattaggaga ttgtgatgaa aaaagtttag gattttatta
      121 aataaagtta ggaggtcttt atttaatgac tatataatac tagaccatcc ttaaattttg
      181 cttaagaaaa aacaagtttt gttatttttt acgattcatc caagtcatcc ctatacaatt
      241 ataggtggat aagatttcaa agcccataga acgatagaag cccaaggttc tttctgtctg
      301 ttctgtcacc agctggactt gataggcatc tttgtaatcc tctaaagcct ctttcatcaa
      361 ggcactacca attccttgac gctgatagat tggtaaaacg attaaatcct gaaccaatac
      421 tgatgagaat ccatctccaa ccaaacgaat caagcccacc acagcatcac catcaagtgc
      481 cagataaatt actaatgaat gagataaggc ctgctccagc atctctggtt gatgggtata
      541 atttgtccaa ccgacagcct gatagagatg taaaacatcc tctagcttga caatttcttg
      601 ctttttaata gtaatcatct caacacctct taaagttctc tcaagctctt gtactgctgt
      661 ccatttttat caaaattttc aggacgcaac catgtttcca aacgatcttt gactttgggc
      721 cagtccttat caatcataga caaccaatcc atatctctcg tacgcccctt ataaaccact
      781 gcctgacgga aggttccttc ataaataaag cccaaacgct ccgcagcacg tctggatggc
      841 aggttaagag catcgcattt ccactcataa cgacgatagt taagctcttc aaagacatag
      901 cgagccagta gatactgggc ttctgtccct atccgtgtcc ccctgagttt tggagaaaaa
      961 gtgacagctc ccacttctat tactccgtta ctggtcaata cgcatgagag aaaaagttcc
     1021 caaagcctta ccagttgcct tgtctatgta gtaaaaacgg tccttacgag ccaacatctg
     1081 atttatagta aattgaaact aaaatagtac acttatactt ctaaaacatt gttagaaatc
     1141 gatttgactg tcctgatcga tttgtcctgt tcttatttca ttttactata aaaggctgac
     1201 cagctcctcc atgtctgcta ctggctcctg aaagaggtag gtccacatct cctgaggcgt
     1261 atcaggccca taaacagcta gcaaatcctc cgcatgcttt tccactgaaa gagcctctat
     1321 cctagcataa cgcccttcta agagttcaat agaagtcagc tcacctggtg tataaccttc
     1381 cattgactcc ccaatcattt gaccatattc atttactggc atagctttct ccttttttca
     1441 cttttcaaac tttatagttg cccatagtat accatacttt cataagaaga ttcaaaaaat
     1501 cctccagatt ctactctgaa ggattcctac cttatttcac aacgatatta acgagtttag
     1561 ttggctcaaa cagtttggga aactgtttga ggttggaaat cagcaaataa attggttatt
     1621 ttacaacaat attaaccaat ttatttggta cactaattac tttcacgatt tccttaccgt
     1681 caatttctgc tttgactttt tcatcagcta aagcgatttc ttgtaattct tcacgtgata
     1741 tatctttagc aaccatgagt ttggcacgga ctttaccttt gatttggaca acgatttcga
     1801 tttcgtcttc aaccagttta ctttcgtccc aagttggcca agctacataa gagattgact
     1861 cacctgtttc tgcgactgtt tgccagagtt cttctgccaa gtgaggtgca aatggtgcaa
     1921 tcaattgaat aaagcctttg gcatagtcaa cataaagctt atcttccttg ttagcagcat
     1981 tgacaaagac cataagttgg gcaatagctg tgttgaattt gagagactca atttgctcag
     2041 taacagcttt gactgtttcg ttgtaagcct tgtcaagagc accattgttt tccgcaagga
     2101 tttctttact tgtaatcaaa cggtaaactc ggtcaaggaa cttacggctt ccttccaaac
     2161 cttcttctga ccaagcaatc gaagcatcga gtggtcccat aaacatttca taaacacgaa
     2221 gggtatcggc accgtattgt tccaccacat catctgggtt aacaacgttc ttgagcgatt
     2281 tagacatctt ggctggcgct tgctccaact cttcccctgt ttctatatga aagaaggaac
     2341 catcacgttt ttcaaccttg tcggttgcca caagagcacc acggtggtca cggtagcttg
     2401 ttcccaaaat catcccttgg ttaaagagtt tttggaatgg ttccttagtc ggaacaacac
     2461 cgaggtcata gaggaattta tgccagaaac gagcataaag caagtgaagt acagcatgtt
     2521 ccgcaccacc cacgtagata tctactggca accattgttt gaggaggtcc tcatcagcca
     2581 atttctcagt attgtgcggg tcaatatagc ggaggtagta ccagcttgaa ccagcccatt
     2641 gtggcatggt gttagtttca cgacgacctt tgacaccatc ttcacgagtc acttcaagcc
     2701 aatctgtcaa gttagctagt ggactttcac cagtacctga aggacggata tccttggtta
     2761 caggcaagac aagcggcaat tcagtttcag gaacagctgt tgaagttcca tcttcccaat
     2821 gaatgattgg aattggctca ccccagtaac gttgacggct aaagagccag tcgcggaggc
     2881 ggtaggtaac cttctcctga ccacagcctt tttcttccaa gcaagccaca atcttggcaa
     2941 tagcgtcttc tttgttcaat ccatctagga agtctgaatt gacatgcagg ccatcctctg
     3001 tgtaggcagc ttcttcgaca tttccacctt caagtacttc gacgattgga aggtcaaatt
     3061 gtttggcaaa ttcccagtca cgttggtcgt gggcaggcac agccataacc gcacctgttc
     3121 cataactagc aagaacatag tccgcaatcc agattggcat ttccttacca ttgacagggt
     3181 tgatggcata ggcacctgtc caaacaccag ttttttcttt agcaaggtct gtacgagcca
     3241 agtcagactt aaggctggct tggtgtttat agtctgctac agcttctgct tgctctgaac
     3301 ttgtgatagc gtctactaat tcatgttcag gagccaagac agtgaaagtc gcaccgaaaa
     3361 gtgtgtccgg acgagtagta aagactgtaa attccttgtc tgttcctttt actttgaaag
     3421 ttacattggc accagttgat ttaccaatcc agttgcgttg catatccttg atagactctg
     3481 accaatctag ttcatctaag tcattgagca agcgctctgc gtaagccgta attttgagca
     3541 tccattggcg cattggtttg cggacaactg gatagcctcc acgctcagaa gttccgtcag
     3601 gaagcacttc ttcattggca atggcagttc ccaattcctc aacccagttt actggcactt
     3661 cagcttcata ggccaagcct ttttcgtaaa gcttggtgaa aatccattga gtccacttgt
     3721 agtagtttgg atctgttgtg ttgacttcac gatcccagtc ataagaaaat ccaagcgcat
     3781 tgatttgacg tttgaagttg gcaatgtttt ccgctgtaaa ttctgctggg tcattaccag
     3841 tatccatagc gtattgctct gcaggcaaac caaaagcatc ccaacccatt gggtgaagaa
     3901 cattgtagcc ttgcgcacgt ttgtaacgac tgaggatatc ggttgcagta taaccttctg
     3961 ggtgtcctac gtgcagacca gctccagacg gataagggaa catatcaagc gcataaaact
     4021 taggttttga tgcatctgtt cctgtcttaa atgtatgatg ttctgcccag tagccctgcc
     4081 acttaggctc aatttcttta tgattgtaaa aactcatggt ctctctccaa ttttgtgatg
     4141 ttactattat accatttttg agggaatttg aaatgtgttt aaaggaaaaa ctgtatactg
     4201 tatctcatta attttgatga ctatgaattg ctctatctcc cactttttat cccattgtta
     4261 tgcagtaaat caaggagtaa gtcaagaagc ttatctcgta tagcacaaaa tacttatttt
     4321 agaccgaaga taaaactgga atgctaatta atgtattcac aataaatagc cgactaccta
     4381 tgtcgctttt tgatttatga agaacgtata gtagactgaa tctgaaatag tacgaaacaa
     4441 ttgctaaaac atttatagaa attaatttta ctttcccaat cgatttgttc tcatcctatt
     4501 tcaatcttct atagaattca atacagggat caataaaaga ctaccatttg gaaaacagta
     4561 gtccttattg tttattttga atttacatag gcatctacag cgataatagc ttgagcaaca
     4621 tctgaaggcg aaatcttaaa cggcatctga tgaattgtct caccctccat agttgcttgt
     4681 ttaccaactt ttattaaatc atcatatcca acttgatcca aatgcatttc ttttagagtt
     4741 gttggcatac caattttttt gtaaaactca atatacttat caagttcttc tttaggtcta
     4801 ttttccaata atagttgtac taaagttcca taagctactt tttcaccatg tgttaaatga
     4861 tgaatgtcac ctgtcaatgc agtaaaacca ttatgaattg catgcgccgc agctaatcct
     4921 ccactttcaa aacctagacc actcaataaa gtattagctt caacaatatt ttctaatgct
     4981 ggtgtcacca ctttagcttc acaagctgcc atagcctgta aaccatctgc aaacagcgtt
     5041 tcttcacatt tcttcgcaat tgcaactcca gccaatgttt gctgttgtcc caacatagtt
     5101 tttccatttg cctgcataac cgcacgcgcc tcaacccaag ttgctaaacc atctgcaata
     5161 ccagacgcta ataaacgctt aggggcttgt gaaataactt ttgtatcaac caaaactaaa
     5221 tctggatttt tagaataaaa tagataatga tcaaatgcac cttcatctgt ataaataaca
     5281 gataaagcag atacaggtgc gtcggtcgat gcaattgttg gagcaataat aacaggcttt
     5341 tcaatcaaat ctgcaatagc ttttgcgcta tcaatcgtct ttcccccacc aagaccgata
     5401 atactatcac aattttcttt ctcagccaag gcaacaactc gattgatttc attgtcagaa
     5461 gcttcaccat taaatagcgc cagaacaata tggaaaccat acctatgtag ataatcttca
     5521 aatcgttttc caacaatatc ataaaccaac tgatcgcata atagaatcgg gtaatttccc
     5581 aaatccaaaa ttgatttggc attttcaaac aaggcatttt ccccctgaat atatctagaa
     5641 ggactagcaa aaattctcat atgtatttcc tctctatcta aatggaacga ctattttgag
     5701 taacaaacca atcgtcagaa aaatcatcaa ccgccttttg gatagatggc atggcgaaag
     5761 ctgattcaaa aacatctgct cctgctgtaa cagcatgcgc acctgcagct aaagcattat
     5821 ttacttgtgc tacattttta aaggatgcag ctaaaatctt actaggagag ttctgtctat
     5881 caatagcaag agctaattga cgaatgacag aatttgaatc aatgttcaga ttttccattc
     5941 tattataata tggagctagg taatccgctc ctgcttcgat agctaataat ccctgaataa
     6001 ctgtataaat agctgttgca gtgatatggt agccctcttt ttttagcgcc tttattgcac
     6061 gtaatccagc tggagtaaca ggtactttga taaatatatc atctcctgct tgtcttcgaa
     6121 ttttatgagc atcctttaag atgccttcaa aatcttgaga aatcacctga acatgaatag
     6181 agggtgtaga gccaatcaat tctcttacat ctttgattcg ttcaaaaaaa ttaatagaac
     6241 cctctctttt tgcaatagtg ggatttgaag ttaccccagc tagcggcaaa atttcagacc
     6301 actttttaat ctcatctaaa tttaatgtgt caagcataaa ttccataaaa agaacctctt
     6361 tattttacaa agtatgctca gtacgtccta taatgtcatc ttgggttgcc ttagaaagaa
     6421 cattgaagaa tgcagagtat cctgcaacac gaacaattaa gtctctgtgt ttttcaggat
     6481 gtttctgagc gtcaatcagc gtctctctgg aaacaacatt gtattgaata tggtacccat
     6541 gtaaacgatt aaagaatgtt cgtaacaaag caattagttt taatttatct tcttctttgg
     6601 ctaacgtttg aggatttact ttctgattta agagaacccc acctacgatt tcatctgttg
     6661 gtaattttga aacagatttt aaaacagatg tagggccgtg ttgatccata ttatgtgatg
     6721 gtgaacaccc ctctgctaac ggtgtacccg cgttgcgtcc atctggagtt gctaatgttc
     6781 cacgtccctg ccctacgttg gctgagatag aagatgttcc tgaataacga attcctccaa
     6841 ttggacctct tccataacgt gtattaggat atttagcaat ttcatcaaca taaatgtcat
     6901 aagcagcagt aaccaatttg tcagcataat catcatcatt accatactta ggtgcatcat
     6961 gaatcaacat ttcttgaatg accttacctt cttctccggc ataatctgtt tccagtgcat
     7021 gccaaagctg acttgggctt atacgttctt cctcaaacac caatttttta attgcagcta
     7081 atgaatccga caaatttgca attccaactt gcaatcctga tatataatca tatactgctc
     7141 caccttcttt aaggtgtttt ccacgaccaa tacaatcatc agtcaatgct gaacatagaa
     7201 tatcaggaac ttctcgttcc aatgataaat caatagaatt ttcaacaata acactcattc
     7261 gtgtcaaata tcttagtgtt ttatcccaag cattttctaa ttcagaaaag ttcttcatat
     7321 ccttaaaatg accaaagctt ggtgcaaacc gtttacccga agccggatca attccatcat
     7381 tcatcgtgat aagtagaacc ttagggaagt tcatataact catacctgtg caacgatagc
     7441 cccatttccc tggaactgcc gtttcaacac atccaatggc actgtaatca taagcatcat
     7501 cttccaatac tccttttgca ataaaagaag gaataataat ctcatcatta ttaaatgcag
     7561 gcataccaaa accaagtttc atcacttcaa tacactcatt catgaaacga gcatctaaac
     7621 ctgcatggta acgtacagtt agattaggtt gcggtagatg ggtttgtgca actgatttta
     7681 agaccaaata agataatggg ttaacagcat ccttcttatc tcgagtctgt ccaccaattg
     7741 taacattttg atataaagga cttcctgctg aagaaaatgt atgtgattga ctgcgaacct
     7801 tattaattgt aattgtctta atccaaagat ttgtcagacg ttcaacaatg ctatcttctg
     7861 tttctttacc actttctaaa tcagccttca tatatggata catatattga tcaaaacggc
     7921 catatgaaag agagtggcca ttagattcaa tttgtaaaat acattgaata aaccaaactg
     7981 attgaatagc ttctgcaaaa gtagttgccg gttcatatgg gactctagag caaatatctg
     8041 caatctcaag taattctttc ttacgtttag gatttgcatt ttcggctaaa cttttagcaa
     8101 gagcaacaaa gcgctttgca tatactttaa tagcatcgat tacgataaat atagagtcgt
     8161 aaaaatgata tttatcaata cttgctggat ctgttaaatc tagagctact tttgctttac
     8221 gagcccgctc ttcaaaacct cttaaaccaa attgcaaaag tttctgatag ttaactgcta
     8281 agtgagcatc tccagaattc atcttacctt ccataccgaa gaatcctgtt tccatataaa
     8341 cagacacttc ttcaggtaat aaggcaccag ctctagcacg taaattatta ttttcccaaa
     8401 acggagcaat acttctaagt tgttcttttg tttcttctgt aatatagaaa acatctccat
     8461 cacgcttttc aaaaagatcc aactcattga gaacaaattc tagcgtatat tccggaaaaa
     8521 taggagcatc tttattggaa gaagcttgat ttcccgcaat catagattct tcttcaatat
     8581 agatagacat attttccaaa atttctttca gcatatatgc acgttttagg acattaggtt
     8641 gttccttgta tcgttcatag gcgcgtgttg ctagaactgc tctctcagca tcaatataag
     8701 gttttttatt taaaacatct tctcgatatt tgttcatcct ttcagtaagg ctgccaaaat
     8761 attctgtctt gattgttgtt cttgctactt ctgtatttac catcgtaagc acctttcttt
     8821 cgaaaatatt tttatttctt tcgaaaatat aataccgatt tttatagaaa ttttcaagct
     8881 tttaactaga aaaattttaa ctctctaatt tttagcacaa atgtgtgagt ttaacagtaa
     8941 cacacaaata cctctaagat tgtttgattt cattttggta agctaaacga tcttgtatct
     9001 taaagaatgg aaagtaaacc actgtagata tcaccaatac taataactga gtcacaacac
     9061 cttgccatcc acccaccaaa aatcctgata gaatagctgg tgtactccaa ggcaatgtta
     9121 cccctgagaa tggttgcatg aaacctgttg caatagctcc atatactatc acagctgcaa
     9181 gtacaggaac aagaatgaaa ggtacaaaca taactggatt catgacaatc ggaaatccaa
     9241 atacaactgg ctcatttacg ttaaatattg ctggaaaagc tgcaactttt cctaaggctt
     9301 ggtattgttt tgattttgct gcaaaaagca tggcaactac aagaccaaac gtaatccctg
     9361 aacctgatag aattaaaaat gaatctaaaa attgttgagt aacaatatgt gcaccatttt
     9421 ctaatgatag attaccagag gctaacatag ctttattagc atcaagatta gataaaagca
     9481 gagctgtcac tactccattt actaccgatt gcccatgaac accaaaccac cacaaaaatg
     9541 atataaagaa tgcaattcca atagcaccat acaaagatcc agttaaacct tgcaacggaa
     9601 cttgaatagc agaataaatc atttctatga atgttccgcc attagtcaat gacttcgcta
     9661 aaatatatac aatcatagaa gataagaaaa ttacaaatgc tggaatcatt gcttcaaact
     9721 gtttggcaat agcttgtgga acttgttctg gcatcttaat aacaattttt ctctttataa
     9781 agaaggtata aatacttcct actaccaaac ctataatgat agcaccgata attccttggc
     9841 ctccaaacca aactttacta atagcgtccc caatcgcctc accttgttta gggatataag
     9901 atgatcttag caaaataaag aatgcagata cagatagaac tccagctggt aaagcctcta
     9961 ctccgctatt cttagcataa gaataggcaa ttgaaaaaca agaaattaga cccataatag
    10021 caaaagttcc tgaatatact tgcataaacg gctctgtcca attagctcca aaaacactag
    10081 caatgctctt atttaatcct tcgaacggca attgtcccat aatcaagaac aaactaccaa
    10141 ctactgtcaa tggcaaaatt gctaacatcc catcttttag agctataatg ccacgcatat
    10201 tcacaaactt catcatcggt gcaatgattt tctgaacatc catctttgac ataataaatc
    10261 tccttttctt acccactaat caaagatagg gccaaatcta atactttttt cccatctaac
    10321 ataccatagt ccatcatcgg aataacagct atcggaacat cacacttatc acaaatttct
    10381 tttgatttat ctaatgtata agcaacttgt ggacccaata gtgcaacatc tatatttggc
    10441 gcataatccg ctaatttaga ctgagaaaac gcctctattt ctgcctcaac tccactagct
    10501 tgcgctgcaa ttttcatatt atttacaagc ataccagtag aaaaacctgc tgcacaaaac
    10561 aaaccaatct tcaccattat gttttcctcc tctatgttaa taacaatgat aatactctag
    10621 tattattttt tatgaagttc ttttctcaaa ctaataattt ctttgattaa attaatctcc
    10681 gtcatactag tcatgagatg atcttgtgaa tgaacaaaga gagctgtaat ttctgtcttt
    10741 gtaccagacg cttcctgtgc caagaatttt gtttgtagat tatgagcttc taataaggcg
    10801 gcatcagcta actggatttc ttcttcacat cgttcacatg taccgttctt tatgtaatct
    10861 aatgctttat aaatatgttg tttcgcatcg ccagcatata aaattaaacc catgataatt
    10921 tgatctggaa caataatttc cataaattcc tcctcatttc actatgtaaa aagctttttt
    10981 catttgaaat tttaaaattt tcttttgtaa ctatagaata caactacata ataaagttgt
    11041 caatccaaaa acaacagata aactattttt gtttatataa gcacaaatgt gcaatcgact
    11101 aaaaagaaaa aacgataaac tgatcagtct atcattttca ctcacctaga atctctctaa
    11161 aagtcaaatc accatcttct tccaaaactt ttaaaattgt atttttatct gtaatcaaat
    11221 gatttactaa attagcacgc aagacagaaa gaatcgaaga tactttcgta tcaccgtaag
    11281 caacagctaa actttgagga atatttttta aatcttccaa agagatggct atcgttcttt
    11341 cctgtaagtt ttcatagact tctttacctt ttgaatcaaa aaatcgacaa caaatttctc
    11401 ctacagtttt aactttggtc aattctttaa agtcatcctc tgtaagcatg tctaaccatt
    11461 gatgtttccc tttattgcta aaatcaccaa ttccgactac agctatatct aaatctttcc
    11521 aactattttt caaattttca aaatatcttg attgcaaaat accatctgct aacaatttat
    11581 tttcttgcac aatcgttgca ttcataaatg tacactctcc atgaaatttt ctagacattt
    11641 cataaatcag tgtattcaca tggtatttag cgtgtatgtg actaggacca cctgctagag
    11701 gatagaagtg aacatttcgg acacttttac tgtgaattaa atctactaaa ttacttaaac
    11761 ttttccccca agaaaagcca attttcatat tatcatcaat tagattccta aggacgcctg
    11821 ctgcaacttg agaaattctt tcagataaaa ttgttggagt atcatcaaat tcatttggaa
    11881 taatttctaa actttccaaa ctgtattttt cttttacata attttccaac ttaaacatat
    11941 tggtatcaaa attctctatt tcaattttaa caattcctac attccttgct tctgttaaca
    12001 ttctactaat agaggttcta taaattccta attttgctgc tatttgtgac tgatttaagt
    12061 tttcaatata atacagataa gcaattttag aaagcagttt attcctatct tgattcatac
    12121 acttaacctc ttacgaaact accttaacca ttatcccagc attttctaat gtagctatat
    12181 tttgtttaga aagtttttcg tctgttatta cttcatagac ttgacttaaa gcaaatcttc
    12241 ttactgtacc tcttttatca aatttacttg agtcagttag gacaatgact ttatccgaca
    12301 ctgctgaaat atattgaact acctcactgc gcattaaatc ttttccggta aagcccatct
    12361 ctttatcgta accatctgtc ccaacaaaag cttgacacac atgaaaagtc tgtatcattt
    12421 cttttaataa aggtcctaca gtcacctgtg aatctttctg aaactcacca ccaagaacaa
    12481 taacacgaca tgaatcataa gctctcacaa aatttgctat aaaaaacgaa tttgttacaa
    12541 tcgtaacatt tcttttttgc ttgcaaattt cctcagcaag taaagcacag gtcgatccag
    12601 attctatcat tattgtttca ttatctgaca ccaattttac tgcttcctga acaatttttc
    12661 tcttagtttc ataattaatt gacaaacgta catttaagtc atctccacta tttaatacag
    12721 catatccatg ctctctgtgt aataaacctt ttgactctaa tttatctaaa tcttttctaa
    12781 tcgttacttt cgatacattt aatttttccg ataatgtatt aacgtcgatc ttttcatatt
    12841 ctgatactaa tttaataatt tgttccaatc ttttcatttt acacctccgt tttattctac
    12901 caaaataaaa agcaaaaaac aacaaattaa cctttcgttc gtaattgttt ttctttcgtt
    12961 tttgtgatag gatagactta tgaagaggag gaactcttat ggaaatatct aaaggaatta
    13021 tttttaatat tcaacacttt tcaattcatg acggtccggg tattcgtaca actgtttttt
    13081 taaaaggatg tcctctgcgc tgtccatggt gttctaatcc tgaatctcaa agaatgaaac
    13141 ctgaaaaaat gaaagatgct caacgagaga aattcacctt agtcggtgaa gaaaagactg
    13201 tagaagaaat tattacagag gtattaaaag acaaagaatt ttacgaagaa tccggtggag
    13261 gtttaacttt atcaggaggt gaaatatttg ctcagtttga atttgctaaa gccatcttaa
    13321 aatcagctaa agaacatcac atacacactg ccattgaaac tactgccttt gttgatcatg
    13381 aaaaatttat tgatttaatt caatatgtgg attttatcta cacagaccta aaacattata
    13441 attctataaa acataaaaaa gtgactgggg tttttaatca aatgattatt aaaaacattc
    13501 attatgcttt ttctcaaaat aaaactatcg ttttaagaat cccagttatt cctaatttta
    13561 acaatagttt agaggatgca gaaaaattcg ctactctatt taactcatta aatatcgacc
    13621 aagttcaact actccctttt catcaatttg gtgaaaacaa atatcgttta ttaaatcgga
    13681 aatatgaaat ggatggagtc aacgcacttc atcctgaaga tcttattgat tatcaaaagg
    13741 tatttctgaa ccaccatatt aattgttatt tctagttcat ttccttgaaa cgctctagct
    13801 atttgcagat aacaagcatc tatataaggt tatcaaagaa gacttcccca tgactctaaa
    13861 tgaatatatc ttacaatatc gcctgaaaca agctatagat aagatggctg aatctcccaa
    13921 ctccccttta agcgctatct ctgaccaagt tggattttca gactataaat attttgccaa
    13981 agtatttaaa aagcatctcc atatttcccc aaaggaattg aaattactcg gaagaatagt
    14041 aaaataggct attcttcttt ttgtagagaa ttttactcta atatagtgaa ttgaaataag
    14101 atgtgaacat ctctatcagg aaagtcaaat taatttatag aaatatttta gcagtcaaag
    14161 tgtactgtta tagattcaat acactataga atagaattgt aggttttaaa aacgcttaca
    14221 ttgttttaaa ataaacttaa ataacacaac ggaggtatcc atcatgaaaa agaaatggat
    14281 gtattatgct gcttgttctt ctaatgaatc tgccgatgac agttcatctg ataaaggaga
    14341 cggtggttcg ctagtcgttt attgaccaaa ctcagaaggc ttaattggag caactattcc
    14401 tgcctttgaa gaaaaatatg gtatcaaaat agaactgatt caagctggta ctggagaact
    14461 tttcaaaaaa ctagagtcag aaaaagaagt tcctgtagct gatgttatct ttggtggttc
    14521 ttatacacaa tatgctaccc acggagaact ctttgaaaac tatatttcaa aagaaaatga
    14581 taatgttatc aaagaatatc aaaacacaac tggcttctct actccttata cactagatgg
    14641 tagtgtttta atcgtccacc ctgatttaac taaaggcatg aacatcgaag gatatagcga
    14701 ccttctcaaa cctgaactaa aaggaaaaat cgcaactgct gacccagcaa actcttctag
    14761 cgcctttgct caattaacaa atatgctaca agctcaaggt ggttacaaag atgataaggc
    14821 ttggtcttat gtaaaagatc ttttcacact tattgatggt atagtaaaat gaaataagaa
    14881 caagacaaat taatcaggac agtcaaatcg atttctaaca atgttttaga agtagatgtg
    14941 tactattcta gtttcaatat actataaaat cggtttaagt tcatctggtg tctataaagc
    15001 agtcgctgat ggagaaatga ctgttggtct ctcttatgaa gatccagcag ttaaactctt
    15061 aaatgacgga gctaacatta aggtagtcta tccaaaagaa ggaaccgtct tcctacctgc
    15121 tagtgctgct atcgttaaaa aatctaaaaa tatggaaaat gccaagaaat ttatcgattt
    15181 tattatctct caagaagtac aagatacact tggtacaacc actactaacc gtcctgttct
    15241 taaaaatgct aaaacaagcg aaaacatgaa accaattgac aaaatcaaaa cactcactga
    15301 agattatgat tatgtcatca agaataaatc agatatcgtt aagaaataca acgaagtctt
    15361 tacagatatc caatctaaac agtaaaagag gttcactatg agtgagatcg aaattattaa
    15421 cgccaaaaaa atctaccacg atgtccctgt tattgagaat ttgaacatta caattccaaa
    15481 aggaagtctc tttacccttc ttggagcttc aggatgtggg aaaacgaccc ttcttcgtat
    15541 gattgcaggt ttcaacagta tcaaagatgg agaattttac ttcgatgata caaaaatcaa
    15601 taatatggaa cccagcaaac gcaatatcgg gctggttttc caaaactacg ctattttccc
    15661 acatttgact gtccgagaca acgttgcttt tggtcttatg caaaagaagg ttccaaaaga
    15721 agaattgatt caacagacca acaagtatct tggactcatg caaattgctc aatatgcgga
    15781 tcgaaagccc gataaactca gtggtggaca acaacaacgt gtcaccttgg catgcgtctt
    15841 agcggttaat ccaagtgttc tcctcatgga cgagccactt agtaatctgg aggccaaact
    15901 tcgcttggat atgcgtcaag ccatccgaga aatccaacac gaagtgggaa ttacaactgt
    15961 ttatgtaacc cacgaccaag aagaagccat ggctatttca gaccaaattg ctgttatgaa
    16021 agatggggtg atccaacaaa tcggccgacc aaaagaactc tatcataaac cagctaatga
    16081 gtttgtggca acctttatcg gacgcacaaa tattatccct gccaatcttg aaaaacggag
    16141 cgacggcgct tatatcgtct tttcagatgg ctatgccctt cgaatgctag ctcttgatca
    16201 ggttgaggag caagctattc atgtaagcat tcgtcccgaa gagtttatca aagatgaatc
    16261 tggagatatt gaaggaacta ttagcgatag cgtctatctt ggactaaata cggagtattt
    16321 cattgagaca ggttttgcct caaaaattca agttagtgaa gaatcaactt ttgaagaaga
    16381 actacaaaaa ggcaatcgta ttcgtctacg aatcaatacg caaaaattaa acatcttttc
    16441 tgcagatggt tcccaaaacc tgataaaagg agtcaaccat ggaacgtaaa aaactaaata
    16501 tttggacagc ctcctctttc ttcatctttc ttacctatct tgtctttctc gtttatccta
    16561 tcgttaccgt gctcaagtaa gcacttatac atgaaggata attctcacta gctaattttg
    16621 tcactttctt tagtaaagcc tactactctg agacactagt caacagtttc agggtttcca
    16681 ttaccgctac tgtcacttcc ttagttgtag gaaccctatt agcttatctc ttctctatgt
    16741 atgacttcaa ggggaagaaa tttctacaaa tattgattat cattgcttcc atgtcaactc
    16801 ctttcgtagg agcctactcc tggattctct tgctgggacg aaatgaggtc atcactaaat
    16861 ttttgacaaa tgccctttat cttccagcta tcgatattta tggattcaaa ggaattatac
    16921 ttgtctttac actgcaacta ttcccactgg tatttctata tgttgctgga acaatgaaca
    16981 gtattgacaa ttctctactt gaagcagctg aaagcatggg gtccttcgga tttaaaccta
    17041 tcgtaacggt tgttttacct ctcctagttc caaccttact agcagctcct tgcttgtatt
    17101 tatgagagca ttctcagact ttggaacgcc tatgttgatt ggcgaaggat atcggacttt
    17161 ccctgtcctg atttataccc aatttattag cgaggttgga ggaaattctg cttttgcaat
    17221 tatggcgatt atcattgcct tggcaatttt ccttatccaa aaacacattg caaaccgcta
    17281 cagtttcagc atgaatctgc tccatccaat tgagcctaaa aaaactacaa aaggaaaaat
    17341 ggctgccatt tatgcaacag tctacggaat tatctttatc tctgttttac ctcaaatcta
    17401 cttaatttat acctctttcc taaaaacatc aggtatggta tttgttaaag gttattctcc
    17461 aaacagttac aaggtagctt tcaatcgtat gggatctgct attttcaata ccattcgtat
    17521 ccctttgatt gccttagttc tagttgttct atttacgaca tttatctcct acctagccgt
    17581 tagaaaacgg aatttgttta caaacttaat tgacagcctc agtatggtac cttatattgt
    17641 accaggaacc gttctaggga ttgccttcat ttcttccttc aatactggtc tatttggaag
    17701 tggatttctt atgattacag ggactgcttt catcttgatt atgtctctat ctgtcagaag
    17761 attaccgtat actattcgct catctgttgc tagcttacaa caaatagcac caagtattga
    17821 agaagctgct gaaagcttag gaagtagtcg tctcaatacc tttgctaaga ttacaactcc
    17881 aatgatgcta tctggtatca tttctggagc catcttatct tgggtcacaa tgatttcaaa
    17941 actctctact tctatcctcc tctacaatgt caaaacaaga acaatgactg tagctattta
    18001 tacagaggtt ctcagaggaa attacggtgt agccgcagcc ttgtcaacta tcctgactgt
    18061 tctaacagta ggttccttgc tcttgtttat gaaaatctct aaaagcaata gcattacact
    18121 ttagttttcc acatcaaaaa cagccgaaag gagtaccctc ggctgttttt tcttatcttg
    18181 atattcttat caaatcccta gctcatggca agcaagtcta gactgattaa atagagcctt
    18241 cttccatctt ctcacgtcct agctctcggt aactacggtc accgacaact tcaaccctaa
    18301 actgaccgtc ctcatattca agaatcgtca cgctaccatt atctagacca tgcggatgca
    18361 tgccactaat cagataaaca atggttccaa tagtcattcc atggctgaca acaagggcgt
    18421 tacctccacc ttgatcttcc atttcttttg caatcatttc aaagccttcc ttgattcggc
    18481 cactgagttt ttcccagcct tcagcccaac cagctgtatc gacctctacc aagccctcag
    18541 ccagttcagc ataagacaat tggtgaacgt ggtccacatt aaagatacga ggaataatgc
    18601 ccatgaaaag atcgccatca taggctccat caaaactacc gaaacaccat tctctgatac
    18661 gcttgtccat gcgataaggg attttcccct gcaagccaag ttcttcaagg ataattccca
    18721 tggtctgaat ggtacgacca gaatcactcg aataagcgcg ctcaaactgt agatcagatt
    18781 ctcgcaaacc gattcctaac tcttgaatcc ctcgttcacc ttcagcagtt aagggagtat
    18841 cgctccaacc ttgcgcgcga ccaatcgtgt taaacatggt cttgccatga cgtaccaaat
    18901 acaatcgtac ttttaccatt ttccgtcctc cgtttgcttc tattatatca tgaatgataa
    18961 aataaaagcc acccatacag gcgacttttg aaggagatta ttatgaaaaa gtttaggagt
    19021 tcattaaata aagatattag atgaaaatca aattcaaact aattcagtgt tatctgtttc
    19081 aaataatatt aggaggtctt tatttaatga ttatagtata cacatctaat cttaaataga
    19141 acttaaaatt tctcctattt tcttaatttt taaaactatg aattggtgct gggatttgtc
    19201 caccgcgaga gatgaagtcg acagacgaag ccccattaac cttcataacg ggtgcagttc
    19261 ctaatagacc accaaactca atcatatcgc cttctcttcc tttgggaatg atacgaacag
    19321 ctgttgtttt catgttgata acaccgattg ctgcttcatc cgcaatcata gccgcaatag
    19381 tttcagcagg cgtatcttct gggatggcaa tcatatccaa tccaacagaa cagatagccg
    19441 tcatagcttc tagtttttct aaattaagag agccattttg cactgcagca atcattcctt
    19501 catcctcaga aacagggata aaggcaccag atagaccacc gacctggtta caggccatca
    19561 ctccaccctt tttaacttgg tcgttcaaga gggccaaggc agctgtcgtt ccatgcgtgc
    19621 caactgtttc tagccccatt tcctcaagga cacgtgccac agagtctcca accgcagggg
    19681 ttggtgccaa actcaagtcc acaataccaa actccacacc cagtctctca ctggccattt
    19741 gaccaaccaa ttgaccgata cgagtgattt taaaggcagt tttcttaact gtttcggcta
    19801 ctacatcaaa gctctgtcca cgaacttttt ccaaagcacg tttcaccaca ccaggaccag
    19861 aaactccgac attgatgata acatctgctt ccccaacacc atgaaaggca cccgccataa
    19921 atggattgtc ctcaacagca ttagcgaata caaccaactt ggccgctccc atatctgaaa
    19981 gatttgccgt ttccttgata attcgtccca tatctgccac agccgtcata ttaataccag
    20041 acttggttga gccgatattg actgacgagc agaccttatc cgtctcagtc aaagcgcgag
    20101 gaatggaatt gatgagaatc tcatctccct tttgataacc tttttgtact aaggcagaaa
    20161 aaccaccaat aaagtccaca ccaatctctt tcgcagcctt atcaagcgct tttgccagaa
    20221 ccacgtagtc cgtcgcatct gtcgctgccc caatcagaga aataggtgtc accgatacac
    20281 gcttattaac gataggaatt cccaactcag ccgcaatttc atcaccaaca gctactaaat
    20341 tagccgcctt tgtcgtaatt ttttgataga ttttctccgc agcacgattg atatctggat
    20401 cgatacagtc caaaagagaa atccccatgg taatggttct aatatcgaag ttttgctcct
    20461 caatcatggc gatggtttca gtaacttgtc taatatccat gatgacctcc tagatattat
    20521 acatagcttc gaaaatcgct gcactctgaa tattgatttt tacattcaaa gtttgcccaa
    20581 aagcttcaaa ttcattacga agataggtaa aatcttgctt ttcatcacta gatacaacag
    20641 ccatcatcgt aaaatattca tccaagacag tttgagagat atcgtcaata ttcaatccta
    20701 attctgcaat tttaccagaa acacctgcaa caattccaga tttatcttta ccaacaacag
    20761 ttataatggc tttcataagt aaactccaat tcttcttaaa ataagaaacc ttaacattaa
    20821 acaggattct tttcaaatag tatagcataa ttctaacgaa aatactcaaa aacgcctgct
    20881 tacgaagttg ttcttaagaa aaaaacaatt tcgtaaacaa gcgtctacta tcccaactta
    20941 tgatgagtgt tcccgctagg accgaaatcc tagcggtaga ccagagctag actaagagca
    21001 caagactcca tcatcataac actcaacaaa attgatgatt ttatactaat tcgatgatcg
    21061 ccattggcgc tgcatcacca cgacgtggtt cagttttaag gatacgagtg tatccaccgt
    21121 tacgttcagc ataacgaggt gcgatttctg agaacaattt ttgaagtgct gtagtagaag
    21181 tgtacttatc agttgcttca tcatagtttt cagatgcgat ttcattacgt acgaaagcag
    21241 ctgcttgacg acgtgcatgc aaatcaccac gtttacctag agtaatcatt ttttcaacag
    21301 ttttacggat ttctttagca cgagcttcag ttgtcacgat tgattcgttg atcaaaaggt
    21361 cagttgtcaa atcgcgaagc attgctttac gttgtgagct agtgcgtcct agtttacggt
    21421 aagccatgta ttcctccttt atttatcttt taatccaaga cccaaatcaa tgagtttgag
    21481 tttcacttct tccaaactct tgcgtccaag atttcgtact ttcatcatct ctgcttcaga
    21541 tttttctgtc aaatcatgca cagtattgat accggcacgt tttaaacagt tgtatgaacg
    21601 cacagacaag tccagttcct caatcgtacg atctaaaata cggtcgtcag attcagtatc
    21661 agcttctttc atcacttcag ttgacttagc aatctcagta agatttgtaa acaaatcaag
    21721 atgttctgtc aaaatacgtg ctgaaagccc taaagcatct tctggaataa ttgttccatt
    21781 tgtcaagatt tcaagggtta atttgtcgaa accatcattg ctacctacac gagcaggttc
    21841 cacttgatag ttgacttttg taactggtgt ataaatagaa tctacagcaa gtgttccaac
    21901 tggtgcatta tcctttttat tttcatcagc aggtacatat ccacgaccac tgttaacagt
    21961 catagtcgct tttagagaag aaccttcacc aattgtaaag agataatgat ctggatttac
    22021 aatttcaata tcgctatctg tcaaaatgtc accagctgtt acttcagcag gaccttcaac
    22081 atccagttcg atgatttttt cgtcttcaac gtacgatttc actgcaattc ctttaatgtt
    22141 cagaatgatt tgcatcacgt cttcacgaac acctggaact gtgtcaaact catgtaacac
    22201 accatcaatg ttgatagatg tcacagctgc tcctggtaga gaagctagaa gtacacgacg
    22261 aagagagtta ccaagagttg taccgtagcc acgttcaagt ggttcgatta caaacttgcc
    22321 ataatcttta ttttcatcaa tttttgttat atttggtttt tcaaactcga tcatttagtt
    22381 actccctctt aaacgaaaag cagtgtaatg cgatgattat acacggcgac gttttggagg
    22441 acgagcacca ttgtgtggca ctggagtcac atcacgaatt gctgttactt caagaccagc
    22501 ggcagcaagc gcacgaatag ctgactcacg accagaacct ggacctttta cagtaacttc
    22561 aactgattta agaccgtgtt cttgtgcaga tttagcagca gcttcagaag ccatttgagc
    22621 agcgaatggt gtagatttac gagaaccttt gaaaccaaga gcaccagctg atgaccaagc
    22681 aattgcatta ccatgcacat cagtaatcat aacaatagtg ttattaaatg tagcgtgaat
    22741 atgagcaata ccagattcga tattcttttt cacacgacgt ttacgtgttg gtttagccaa
    22801 gacttttacc tcctatatta ttttttctta ccagcaatcg caacagcttt acctttacga
    22861 gtgcgggcgt tgtttttagt gttttgtcca cggacaggaa gtccacgacg gtgacggata
    22921 ccacggtatg aaccgatttc catcaaacgt ttgatgttca agtttacttc acgacgaagg
    22981 tcaccttcaa ctttgattgc atccacttca cgacggatag catcttcttg atctgatgta
    23041 agatcacgta cacgaacatc ttctgagatt ccagcagcag ccaaaatttt cttagatgtt
    23101 gcaagtccga taccataaac ataagtcaat gagattacta cgcgtttgtc atttggaata
    23161 tcaactccag caatacgagc catgttttct cctttctatc ttatccttga cgttgtttgt
    23221 gttttggatt tgctgggcaa attaccataa cacgaccatt acgacgaata actttacagt
    23281 attcgcaaat tggtttgacc gatggtctta ctttcatttc ttatccctcc aagtttttcg
    23341 attatttaaa gcggtaagtg atacgtccac gtgtcaagtc atatggactc atttcgacag
    23401 taacacgatc tcccgctaaa atacgaatat agtttttacg aattttacca gaaactgttg
    23461 ctaaaatctg atgtccattt tcaagttcaa ccgtaaacat tgcattcggc attgtatcaa
    23521 ctactttgcc ttcaacttca atcacatcgt cttttgccac gcaaaagcac ctccataaat
    23581 ttcgattcga tgcctctaga cacagagaca acaattataa gtcagactat ctcagtataa
    23641 catttgtagc gaatttttgc aagtatgaaa aacgctttat ttcaaatttg tcaatacttt
    23701 ttcaatatct gagaagacat cattgatatc ttgattacct tcgatgtcat gaaccaaacc
    23761 tttggcacgg tagtgagcaa tgattggttc tccttgagca atattaacat ccaaacgacg
    23821 ttttactgtc tcaggcttat catcttcacg ttggtagtaa tcttcttctt tatagtcaac
    23881 tggtgggtta aagaccttgt ggaaagtttc tccagttacg cggtggatga tacggccact
    23941 caaacgttcc aagaggctgt cagggttcac ttcaatattg ataacacctt ctagttcaat
    24001 gccaagttca gccaatgttt tgtccaaggc atgagcttgt tcaattgtac gtgggtaacc
    24061 atccaataag aatcctgttt ctttaatatc atcttgtgaa aggcgttctt ttacgattcc
    24121 atttgtaact tcgtcaggaa ccaattcacc cttgtcaata tatgacttag caagaacacc
    24181 catttcagtt tgatttgcca ttgcagcgcg gaacatatca cctgttgaga tatgtgcaac
    24241 atggaattgt tctacgattt ttgctgcttg agttccctta cctgcaccag gtaagcccat
    24301 aatcaaaaga ttcatgattt gatctcctta ttttattttt aaatagaagc aaaaagtctt
    24361 ttcaccccta tttaaaaaca aaatagaaga ggggagatcc aactcttaca aatgtcagag
    24421 tttaaacctc cactccctca gcatttactg attcagtaaa tacttttatt ctgttctgtc
    24481 catgaaacca acatacttac gtttcaatag gtaaccttcc aattgcttga ttccttcgat
    24541 acctgtagag ataatgatca agagacttgt tccaccaaag gcaacaacat cagaaagacc
    24601 aaatacatct ttagctgcaa tcggtaaaat ggaaatcaca ccaaggaaga gggaaccaac
    24661 agttgcaaga cgacgaagaa gtttagacat atattcttct gtacctttac caggacgaac
    24721 tccatggata taggcaccac tcttttgtag gctctctgct gctttttcag gattaatctg
    24781 tacaaacgta tagaagaatg taaagagaat aatcaacaaa gcatacatgg caataccagt
    24841 tggagaagta gttgccaaca tctcttgtgc tacccttacc caagcccaat catgacctgt
    24901 ggcactcaaa aactgaagaa tagccgcagg cgctgcagta atcgaactgg caaagataac
    24961 agggataact ccagcagggt ttacctttaa cggaaggtaa gagctagatg gagcaccttg
    25021 tgcaacctta gtatattgga ttggaatttt gtattctgct tgttgaacat aagttgtaaa
    25081 gtaaataatc aacaatacag taataatcaa aatgattacg aaaatgatag atgaagtgat
    25141 acggctactt gggacgttca caaagtagtc cacatagatg ccctgaatca tctctggaat
    25201 tgaggaaaca atcccggcaa agataatcat ggaaacaccg tttccgtatc ccttatctgt
    25261 aatttgctca cccaaccaag tgacaatcat actaccagct gttaagatga taccaatcgt
    25321 cagaaaaact tgtggagtta aagcagtttt aatcaattga gctccagcca aggtattaaa
    25381 accagctgta atcccgatag attgcacaaa agcgagaact agagcaatat aacgagtagc
    25441 ttgattcaat tttcttcgac ctacttcccc ttgtttaccc cactctacaa acttgggtaa
    25501 aatatccatt tgcaagagtt ggacaacaat agaagcggtg atatagggac taactcctag
    25561 ggcaaaaatc gaaaagtttt ttagggcatt ccccgacacc aagctcaaca tgtttaagaa
    25621 ggataatcca cttaaagcat tcaagctatt ggcattcaca ccaggaactg taatgctagt
    25681 tccgatacga aagaccaaaa cgataaaaat tgtaaataaa atttttgatc gaacctgctt
    25741 gactttaaga gcttctctta ataatttaaa aaacataggt cacctctctt agatgacttc
    25801 tactgaacca cctttagcag tgatagcttc ttcagctgat ttagagaatt tagctgcttt
    25861 cacagtcaat ttcttagtca actcaccgtt accaagaatt ttaatacctg acttttcagc
    25921 tttaacaatt cctgcttcga taagaacaac tggagttact tcagcaccat cttcaaagac
    25981 gttcaattgg tcaaggttca caattgcgta ttctttagcg ttgatgttag tgaatccacg
    26041 ttttggaaga cgacggaaca atggagtttg tccaccttca aaaccaaggc gaactccgcc
    26101 accgctacga gctttttgac ctttttgacc acgaccagat gttttaccgt tacctgatga
    26161 agtaccacga ccaacgcggt tacgtacttt acgagaacct tctgcaggtt tcaattcatg
    26221 aagtttcatt tttattttct cctcttttgt aaaatgctag cgccgataag ggagaaaagg
    26281 ttgtctcccc catcaactcg cctatacgat gtcatcatag atgactatat ctagttttag
    26341 gggatggtac agtgcacatc ccctaaaact tcattagttt acttcttcaa ctgttactaa
    26401 gtgagatact gctgtgatca taccacggat agcagcgtta tcttctttaa taacagagct
    26461 gttcaatttg ccaagtccaa gtgctacaac agttttacgt tgtgatggaa tgcgtccgat
    26521 tggagactta gtcaaagtaa ttttaatttg agccatttta tcccctttct tatgccaaat
    26581 cagaaactga aataccacga agggcagcaa tttcttcagc gcgtttcaat tgtttcaaac
    26641 cttcaacagt tgcacgaaca atgttgattg gagtgttaga accaagtgat ttagatgtaa
    26701 tatctgccac acctgccaat tccacaacgg cacgaactgc accaccagcg gcaactccag
    26761 aaccttctac agcaggtttc aacaatactt tagctccacc gaattctgaa agaacttcgt
    26821 gtgggattgt tgttccaacc ataggaactt cgatcaagtt tttcttagca tcatctactg
    26881 ctttacggat tgcttctgga acttcttgag ctttaccagt accaaatcct acgcgaccat
    26941 tgtggtcacc aacaacaaca agagctgcga aacgaagacg acgtccacct ttaacaactt
    27001 ttgtaacacg gttgacagca actacgcgtt cttctaattc aactgcattg tctttaaatg
    27061 ccattttcta gtgtcctcct attagaattt caatccgttt tcacgagctg catcagccaa
    27121 agctttcaca cgtccgtgat atagatatcc accgcggtcg aacaccactt ctgaaatacc
    27181 tttagcgttt gcacgttctg caacgagttt accgacagca acggcttgtt cagttttagt
    27241 tccttttgaa acttctttat caagagttga agcacttgcg agcgttacac ccgctacgtc
    27301 atcaatcact tgagcgtaga tgcctgtatt agaacggaat acgttcaaac gtgggcgatc
    27361 agcagttcca gagagttttc cgcgaacgcg acggtggcgt ttttggcgga gtttgttttt
    27421 atctggtttt gaaatcacag ttttcacctc tttagtttta aatcgtgtgc tatgcacaaa
    27481 gttggaaaat aggttggtgg ttgatgatca accactcaac attatttacc tgttttacct
    27541 tctttacggc gaacgaattc accaacgtaa cggatacctt tacctttata tggttctggt
    27601 gaacgaaggc tacgtacgta agcagctgtt tgaccaacta cttcttttga aattccgcta
    27661 acaacgattg ttgttgggtt tggaagttca aaagtaattc cttctggagc ttcaacttcg
    27721 tctggatgag atttaccaac agccaaaaca agtttagatc cttgaagctg tgcacggtaa
    27781 ccaaccccac gcatttcaag ttctttcttg aatccttctg atacaccaac aaccatgttg
    27841 ttcaaaaggg cacgagtagt tccgtggata gttttcattt cttttgaatc gtttggacgg
    27901 tgaagagtta tttcagtacc ttccacacgg atttcaatat cttttgagaa ctcacgagta
    27961 agttctcctt taggtccttt tacagttaca acgttgtcat tgttagcgag ttcaacacca
    28021 gcaggcaaca cgataacttt attaccaata cgtgacatgt ttattttctc ctgttaaatt
    28081 gtcaggccag aacggccagt tttcacgggg ttcagatact tatttagttc aagagctgaa
    28141 ctgaacacgc tctaagaact gtgcaaaata gataagttgg cttgtttgta aacaaacttc
    28201 tccaacttcc taattttgct ttgttcttta cgagctttgt atcttgattt taccaaacgt
    28261 aagcgataac ctcaccacca acattctttt ggcgtgcttc tttatcagta agcaaacctt
    28321 cagaagttga aaggatggca attccaagtc cgttaagaac ttttggaagg tcttcacgtt
    28381 ttttgtagac acgaagtcct ggtttagaaa cacgtttcaa gttagtgata actttctcac
    28441 catttggtcc gtatttaaga aatacacgga tgacgccttg tttgtcatct tcaatgattt
    28501 caacgttttt tacaaaacct tcgcgtttaa ggatttcagc aatccctttt ttgatgtttg
    28561 atgcaggtac ttcaagtact tcgtgtttag cttggttagc attacgaata cgagttagga
    28621 agtctgcgat tgggtcagtc ataaccattt tgtttttctc ctcttactag tagtttgcaa
    28681 gttgcacttg ctagttaata catgatacaa agagcgtaac agcacgagca aaaatagaca
    28741 atttaatgca gaagcaatgc tccaaagcaa attggtcttt ttttccaaag ctgtagctcg
    28801 tgttcaaatt ggcaagccca attgaacccg ggctaaactc tgtgtgaaaa agataaactt
    28861 tcctagaaac tttagtttct tcgtcaagtt tcctattttt acttggagtt ttgacgctct
    28921 tgatatctta aattaccaag atgcttttgt tacaccagga atttgacctt tatgcgcaag
    28981 ttcgcgaaaa gcgatacgac tcagaccaaa tttgcggtaa actgaatgtg ggcgccccgt
    29041 aactctacaa cgattatgta aacgagtcgg tgaggcgttg cgaggtaatt tagataaacc
    29101 ttcgtagtcc cctgccgcct ttaatgcagc acgtttttca gcataacggt caacaatttt
    29161 ttggcgttta gcctctctag ctaccattga ttttttagcc attagattta cctcctatat
    29221 tattttgcaa aaggcattcc aaggcctgta agcaatgcac gtgactcttc gtcagtgtta
    29281 gcagttgtta cgataacgat gtcaagacca cgagttttgt caacgtcatc gaagttgatt
    29341 tctgggaaga ttaattgttc tttcacacca agtgtgtagt tcccgcgtcc atcaaatgat
    29401 tttgttggaa caccgtggaa gtcacgtaca cgtggaagtg aaactgatac caatttatcc
    29461 aagaattcgt acatacgttc accacgaagg gtaacttttg caccgatcgc aacaccttca
    29521 cgaagacgga agccggcgat tgatttttta gctttagtga taagtggttt ttgacctgag
    29581 ataagtgcca attcttcagc agctttttca aggcttttag cgtttgatac agcttcacca
    29641 acacccatgt tcaaaacaat cttatctact ttaggcacag ccatcactga tgagtagttg
    29701 aattgttctg tcaaagcagg aactacttca ttaagatatt tttcttttaa acgatttgcc
    29761 attatacttc tcctttcctt cgtgattaat caagcacttc gcctgatttt ttgttgtagc
    29821 gaactttttt accgtctaca aatttgtaac caacacgacc agctacacca tttttgtcca
    29881 aaacttgaac atttgatacg tggatagctg cttctttctc gatgatacca ccttgaggaa
    29941 gctcgttagt tggacgttgg tgtttcttaa caatgttaac accttcaacg ataactttgt
    30001 ttacttttgg aagggcagta aggacaacag cttctgttcc cttatcttta ccagcgatta
    30061 cgcgaacttt gtcgcctttt tttacaaaca ttaggtttct ccttgatttt tcttacgccc
    30121 ataagggcac cctagcttga agctagggga ctagtttgtt cctaaaaatt aaagtacttc
    30181 tggagcaagt gacacgatct tcatgaaacc accttcacgc aattcacgtg caactgggcc
    30241 aaagatacgt gttccgcgag gagttttgtc ttcacggatg ataactgctg cgttttcgtc
    30301 aaatttgatg tatgaaccat cagcacgacg agcacctgat ttagtacgaa cgataactgc
    30361 tttaacaacg tcaccttttt taaccgcacc accaggagta gcttgtttta cagatgccac
    30421 gataacatca ccgatgtttg caaatttacg tcctgaacca ccaagaactt tgatagtcaa
    30481 gatttcgcga gcaccgctgt tgtctgcgac tttcaaacga gtttctgttt gaatcatttc
    30541 agttttctcc tttcaggttt gattagatga tgaccgcttc ttcaacaact tctacaagac
    30601 ggaaacgttt tgtagctgaa agcgggcgag tttccatgat acgtacgata tcaccttctt
    30661 tggcaacatt gttttcatca tgagctttgt attttttaga gtagttaata cgtttaccat
    30721 agactgggtg gttacgtttt gtttcaacta caactgtgat tgtcttgtcc attttgtcag
    30781 atacaacacg tccaacaaga actttacgat tattgcgttc cattgaaatt tctccttccc
    30841 tagtctatta tttcgcttca gattgaactg ttttgatacg agcgatttgt tttttaactt
    30901 ctttcaagcg agctgtttgt tccaattgac cagtagcagc ttggaaacga agttcaaaca
    30961 attctttttt caattcgttt tcgcgcttcg cgagttcttc ttgagaaaga ccacgaagtt
    31021 ctttaacaaa ttcttttact tcattaagtt tcatgccttc tccttattct gcttcacgtt
    31081 ttacgaattt acatttaact ggcaatttgt ggctagcaag tcgaagcgct tcacgtgcaa
    31141 tctcttcaga tacaccagcg atttcgaaca tcactttacc acgtttaact ggtgctaccc
    31201 aaccttcagg tgccccttta ccagatccca tacgcacacc gatagcttta gcagtgtatg
    31261 atttgtgtgg gaagatttta atccaaactt taccaccacg tttcatgtaa cgagtcatgg
    31321 cgatacgagc agcttcgatt tggcggttag tgatccagtg gctagttgta gcttgaagac
    31381 cgtattcacc gaatgctact tcttttccac cttttgcttc accgcgcatt tttccacgga
    31441 attcacgacg gtgtttaaca cgtttaggta ctaacattgg ttatttacct cctttagtgt
    31501 ttttacgagc tggaagaact tcaccacggt agatccatac tttaacacca agtttaccgt
    31561 atgtagtatc tgcttcttcc caagcgtaat cgatatctgc acgaagtgtg tgaagcggaa
    31621 cagttccttc agagtagcct tcagcacggg cgatatctgc accgttcaaa cgacctgata
    31681 cttgagtttt gattccttta gctccagcac gcattgcacg ttggattgct tgtttttgtg
    31741 cacgacggaa agcaacacgt tgctccaatt gacgagcaat tccttcacct acaaggtgag
    31801 catccaaatc aggttgtttg atttcgatga tgttgatgtg tacttgtttt ccagtcaatt
    31861 tgttaagttt tgcacggagt gcatcaacgt tagcaccacc tttaccgata accatacctg
    31921 gtttagcagt gtgaagtgaa acgttaactt tgtttactgc gcgttcgatt tcaatagttg
    31981 aaactgctgc gtcagcaagt tctttttgaa cgaatttacg gattgcaaga tcttcatgaa
    32041 ggtaatccgc gtattctttt tcagcatacc atttggcatc ccaatcacgg atgatgccga
    32101 cacgcatacc aattggatgt actttttgac ccacgatttt acctccttat ttttctgcaa
    32161 cagctacagt gatgtgagct gtacgtttgt tgattggtga agctgaacct ttcgcacgtg
    32221 gacggaaacg tttcatagtt ggtccttcgt ttgcgaatgc ttcagatact accaagttag
    32281 ctttatccaa accaaagttg ttttcagcgt tagctacagc tgagttcaaa actttcaaga
    32341 tgatttcagc agctttgttt ggagtgaatg tcaagattgc gattgcatcg gctacgcttt
    32401 taccacggat gttatcaaga acaagacgtg atttacgagg tgaaacacgt actgtacgag
    32461 ccattgcttt agctgaagta atttctgcca tttatgttct ccttattttc tacgtgtttt
    32521 cttgtcgtct gcagcgtgac ctttgtaagt acgagttggt gcaaattcac caagtttgtg
    32581 gcctaccatg tcttcttgga tgtaaacagg tacgtgttta cgtccgtcat aaactgcaat
    32641 agtgtaacca atgaaacttg ggaagatcgt tgatcgacgt gaccaagttt taataacttt
    32701 tttcttttcg tcgttagctt gagcttcaac ttttttcatc aaatgctcat cgacgaaagg
    32761 tcctttttta agactgcgtc ccatttttat attttctcct ttaaatgttg taccacagcg
    32821 gcttgcactc ctatggagcg ctaccgagct ggcggattta ctagttgctt aagcgactag
    32881 tttaatatta tttctcgttg cgacgacgaa cgataagttt gtcagatttc gctttcttgt
    32941 tacgagtttt aagaccaaga gcaggtttgc cccatggagt agatggtgct ttacgaccaa
    33001 ctggtgcttt accttcacca ccaccgtgtg ggtgatcgtt agggttcatt acagaaccac
    33061 gaactgttgg gcggatacct ttccaacggc tacgtcctgc tttaccaagg tttacaagtc
    33121 catgttgttc gtttccgaca acaccaactg tagcacggca agttccaaga atcatacgaa
    33181 cttcacctga ttgaagacga acaagaacat atttaccttc agaacccaat acttgagcag
    33241 atgcaccagc agcacgtacc aattcaccac cacgacctgg tttcaactcg atgttgtgaa
    33301 tcaaagtacc aactgggatg ttagcaagtg gaagagcgtt tccgactttg atatctgctt
    33361 ctggacctga aacgatacgt tgacctactt caagaccttt tggagcgatg atgtatgctt
    33421 tcacaccgtc agtgtagtgt acaagagcga tgtttgcaga acggtttgga tcgtactcga
    33481 ttgttttaac aactgcttca acgttgtctt tattacgttt gaagtcaacc aaacggtaga
    33541 aacgtttgtg tccaccacct tggtgacgaa ctgtgatacg accgttgttg ttacgaccag
    33601 ccttgctctt caatgcaaca agcaatgatt tttcaggagt gcttgttgtg atttcagcga
    33661 aatccaaaga agtcatatta cggcgaccgt ttgttgttgg tttataaaca cgaattccca
    33721 cgatatttcc tccttagatt attcagcttc agcagcaaac aactcgattg ctttagaatc
    33781 agctgtaagt gtgatgatag cttttttagt tttgttagta aaaccagtgt aacgtccaac
    33841 acgtttagct tttggtttta cgttgattgt gttaacattg gcaactttaa caccttcgaa
    33901 agcagcttca acagcttgct tgatcaaaag tttgtgtgca cgagtgtcaa cttcaaatac
    33961 atatttccct gcttcaagtt gagccattga gctttcagtg atgacaggtt ttttgataac
    34021 atcatacaaa ttcattatgc aagaacctcc tcgattttag agatagctgc ttgtgtgaca
    34081 agaagtttgt cgctatttgc gatgtcaaga acacttgcag ttgtagcagt tgcaactttc
    34141 acgtttggaa ggttacgagc tgaaagagct gcgaattcat ttccttcttc aaggataaca
    34201 agaactttag aatcgatgct caatgctgca agaacttttg caaattcagc agtttttgga
    34261 gctgtaaatg aaagagcgtc tacagctacg aatttgtttt cagcaacttt ttcagagtaa
    34321 actgatttaa gagctaggcg acgaactttt tgtggaagtt tgtagccgta tgaacgtgga
    34381 gttggtccga agacaacacc accaccacgc cattgtggtg agcggataga accttgacga
    34441 gcacgtccag ttcctttttg acgccacggt ttgcgtccac cacctgatac tgcagagcgg
    34501 tttttaacag cgtgtgttcc ttgacgaagg cttgcgcgtt ggctgatgat tacatcaaac
    34561 acaactgatt catttggttc gataccaaat actgcatcgt taagaacaac ttggccagct
    34621 tctttaccag tttggtcaaa taatgttacg tttgccattg tgactgattt cccctttctt
    34681 tattatttac cagctttaac tgctgatttg atagtgataa gagatttctt agcacctggt
    34741 acgttacctt tgataaggat aacgttcttt tctggaacaa cttgtacaac ttcaagattt
    34801 tgaattgtta cgcggtcacc acccatacgt cctgcaaggt ttttaccttt gaatacgcgg
    34861 ttaggtgcaa caggccccat agaacctgga cgacggtggt aacgagaacc gtgagccatt
    34921 ggtccacgtg attgtccgtg gcgtttgata acaccttgga aacctttacc tttagaagta
    34981 ccagttacat caacaacatc tccagctgcg aatgtttcaa ctgtgatttc agcgccaact
    35041 tccaagcctt caacgttttt gaattcacga atgaagcgct taggagccgt gttagctttc
    35101 gctacatgtc ctttagcagg tttgttgctc aatacttcgc gtttgtcatc gaaaccaact
    35161 tggatagcgt tgtatccgtc tgtttcaaca gttttaactt gaagaacaac gtttggagtt
    35221 gcttcaataa ctgttacagg gatcaattcg ccagcttcag tgaagatttg agtcattccc
    35281 acttttttcc ctaagattcc ttttgtcatg agaaaatagt tccttttcta tattttttat
    35341 tcaaaaagtt tttaacgagc gttttttatg ctcaagtcta agatacaaag ggcgtcaaac
    35401 tcaaagtgaa aataggaaac taacgcagtg tctaacggac aataggaagt ttatcttttt
    35461 cacaccgagt ttagtccgtg ttcaattaga ttgaaacacc agcctctgct cttttatatt
    35521 ttagattaaa gtttgatttc tacgtttaca ccacttggaa gatccaattt catcaaggca
    35581 tcaactgttt tttgagttgg gttaacgata tcgatcaaac gtttgtgtgt acgcatttca
    35641 aattgttcgc gagagtcttt gtatttgtga gtcgcacgaa tgattgtgta gaggctacgt
    35701 tcagttggaa gtgggattgg acccgcaact tgtgcacctg tacgagtagc tgattctacg
    35761 atttttgcag ccgctgtgtc aagcgtacgg tgttcgtaag ctttcaaacg gatacggatt
    35821 tttttgtttg ccatcttttt ctccttttcg tctatttaag ataataggct agctccacaa
    35881 gaaaaccgac acggtgttgc gtggcaatgc aaccgagcgt gtcgcaacct cttgtatcaa
    35941 aactaaggct gtaatttaca gcaccataat agaataacac aaatcccctg cgattgcaag
    36001 ggatttgtta ggttttttcg tttttttggg atgaaactgt tttcctactt tttcttccta
    36061 aaattaggga ttttcttcta tatttcttct atacataagt taagtcctct tgacatcaaa
    36121 tttatcttct gattgatcca ctaagatatc cgccttagac tcagtttctt tatagtatcg
    36181 cagatactgc tcccgtctca tctgatggct agccaatata aaggatgcat cacgatttct
    36241 cacagtcgta tctctagcaa ggcgtcgctt taattcggtc tcctcatccg tgtagaaaca
    36301 gatggttttt tcaaagagtt ccttgggtag aaagccaaca gacatccctt cgacaatcaa
    36361 aattggtttg gctccagaca agacctcact agccttccaa ggttcttcaa ttgtcaagac
    36421 atccataccc gcctgcaagg caaggatatc tctctgcaaa ctctccagtt catgcgccac
    36481 tggcagactg gctgtcacct tttgattcgg cgcgtccttg ggtactacca gatggcgtcc
    36541 tgaggtgata taaggatctg tctctagcaa atttactgta gtagaatcta aagcttggta
    36601 caattcctgt gcaaaggttg atttacctga agctccatga ccgtatattc ccagtgtcct
    36661 gactttcccc gtctcgatct ctgagactag ttggtctact aagtcctttt tcttcattct
    36721 ctcttcacct gttcatagct ttcttttccg tcattgagct tgtcccaaat cactacttgc
    36781 ccacttttga gcgatttttg cacatcgata attcgttggt tagacgaacc tcgaaactgg
    36841 agcataagat ttctcttagt tcgatcatat cttccatcga caagaatgtc aatcagtgac
    36901 aagagttcca gtttatctgg agtttccaac atcatttctt cccaagtgta gccggtccag
    36961 gaccaaatgt ccttgtctgg caattccttt cggatgcgtt taactagagg caagagaatg
    37021 ccagtattaa gaaaaggctc ccctcccagc aaagtcaagc cttgaacata gggttgggca
    37081 aggtctgcca taatctgctc ttctaattct gctgtataga gaatgccagc attaaaagac
    37141 caagtcgcaa cattataaca tccctcgcag tgaaacatac agcctgatac atagagagag
    37201 ttacgcacgc cttcgccatc aacaaagtta aaggccttgt agtcaatgat acgaccttga
    37261 ctaagttcct cgcttttcca ttcttgtggt tttggattat tcattcgcta cctctatcca
    37321 ataacgctcg actccattgt gagcatcctc aaatattcca ccatttgcta gaatgactgc
    37381 tctgctagca ggattattca cgctacaggt caccagagct ttcttgatgt tcttttcctt
    37441 agcaacttgc aagccctgac ggagagtctc ttttgcataa cccttgcctc tttcagatgg
    37501 acggatggag tagccaatgt gcccaccttc ttctagtaga aagttactga ggcgcaaccg
    37561 gagattaaga aatccaactg cttgaccttt ctcagaaaaa gccactaact gaattgcagg
    37621 aacccatcct tcaggcagat taatccccat ttcctgttcc tgattgcttt ccaaccactc
    37681 ttcatacaca aaattctctg tatcccaaaa tcctccatca tgggctgatt ggctcttttc
    37741 aaactctgtc atcatatcta aaacagcttt cttatccgct aatcttggtc tgcgtaattc
    37801 catccttacc tcccactatg agaaaagcga gagctggctc tcacttttat tttttcttgt
    37861 tcttgtttaa aaattgttct ctgaagctaa gcaagcgttc tttcttacca gctccacctt
    37921 tagagtgttt ctcgtgataa cgggtcactt gtgcgcgccc cttatcgtct agttgatatt
    37981 ttcccatttc atttctttct aatttgttac ttgatgccca gctattttaa tcgttgaacc
    38041 attcatatgt ttgacacgcg cagcgatttc cttgtgacgc ccgttgacca tcggtcttgc
    38101 ttgaggatta cctaggtagc cacaagttcg cttcaccaca tctactgttt tagggtcgct
    38161 attgccacag tttggacaag caaaccctct ctcagttggt tcaaaatccc cttcaaagtc
    38221 acacttgtag caacggtcaa tcggagtatt ggtgcctaga tagcctacac ggtcataagc
    38281 ataatcccag acagcttcca aggcctttgg attttgctga aggactggat actcacaata
    38341 atggatgaaa ccacctgacg cacctgcttc tggatagact ttctcaaagt ccaatttttc
    38401 aaacggtgtt ggatttttac gaacatcgta gtggaaagag ttggtgtagt attccttgtc
    38461 tgtgatatca ggaatagagc caaacttgtc tatatctagt cggcagaaac ggtctgtcag
    38521 actttcggat ggtgttgagt agatagagaa atggtagcca tattggtctg accactcttc
    38581 tacacggcgt ttcatatcgt gaatgatgtc tagcgtgaat tccttagcat ctggattact
    38641 ttcccagctg ttaccaaaga aaactgtcgc tacttcatac aagccgatat agcccagcga
    38701 aacggtcgca cgacgattct taaagagctg gtcaacactt tcttctttac ctagacgatg
    38761 gccaaaagca ccgtactgat aaaggatagg agcattcgct ggtgtcgcct ctttagtgcg
    38821 ttcgacacgg taaacaagag catcttctgc gatattcatt cgctcgttga agatttccca
    38881 gaacttattc atatcacctt cagactcaag agcaatacga ggcagattaa ccgtcacaac
    38941 acccagattc atgcgacctg aattgacttc tacaccattt tcatccttcc atccttggag
    39001 gaaagaacgg caacccatag gcaccttgaa ggatcctgtc aagtcaacaa tcttatcgta
    39061 agataaaaca tctggataca tccgtttggt tgcacactca agagccaact gcttgatgtc
    39121 gtagttggga gttccttcct ctaaattaag gcctcttttc agagtgaaaa taagtttagg
    39181 aaagatagcc gtacggtgtt ctgaaccaag acccttgatg cgaatgttta aaatagcttt
    39241 ttgaatttct cgttcaaaac gactggttcc cagaccaaaa cctagcgaag taaaaggtgt
    39301 ttgtccattt gaagtgaaga gagtattgat ttcatactca agagattgca tggcatcgta
    39361 aatgtccttt tgcgttttct tccaagcgta atcttcccgt ttttcaggca atacccactc
    39421 ttctgcatct ttgagatgtt tttgatagtt cttctctgca taaggcgcca aaatttcatc
    39481 gatacggtca gctgaacagc caccgtactg gctagaagca acgttggcaa tgatttgaga
    39541 aatctgtgct gtcgcagtct ggatagactt gggactctct acctctgcat ttccaatctt
    39601 aaaaccattt tccaacatac ccttaaaatc aatcaaacag cagttggtca taggggtata
    39661 gggactgtag tccaaatcgt gatagtggat atcccccttt tggtgggcat tggctacgtg
    39721 cttaggaagc atttgcagtc cgattgattt cccaacaatc cctgctgtca aatcacgctg
    39781 agtgttaaag acatcactgt ctttattagc attttcattg acaactgtct ggtctttgtt
    39841 gagaagttta tgaatactaa agttgatatc cgtcgctttt gagcgctcaa aatccctctg
    39901 tgtccgataa gtaatatact cctcagccag cgcatattct ttggcttcaa ggagttcatg
    39961 ttctacgata ttttgaattt cgtaaatctt aattccctgt ggaaagcgac tatgaatttc
    40021 tgtaataatt ctctcagtca gatcattgag gcgtttttca accaggggtg tcacatccat
    40081 aaccttgtca gctgccttgt ggagagcctt gtcaatcttg tccacatcaa atacaacacg
    40141 tctcccatct cgtttctcga cgaagagagt tggcaaaatt gtaatttttt cttctagtgc
    40201 aatcatatgc atgctctttt ctaaaatgtt ctttctaaaa agtattatac cactctaaaa
    40261 agaaaaatca atatcttgtg ttaaaaatct taaaattttt aaaaatacac aagatattga
    40321 tttggttatt taattttata gactttaaac tctgagtaat cagtctttac ttgttggtaa
    40381 ttttctttta agagtgtttc cacttcagac cagacttcca ccttgtcatt taccacaatc
    40441 accttaggtt gtttttcttt caagtcatta agtaacttat tacgattttc ctcagttgct
    40501 gtatagtgca acggggacaa aatcgccgat ggcgacaagc gctcactctt acgataaaga
    40561 gtcgcagtat catcccatgc atagatagca tcttccgtat ttgtctcctc ttttaccaaa
    40621 tcagcaagac gattacgttc ttgataaggt actggataaa ggacaaactt catcaaaaaa
    40681 ggaacagaca aaagatagac aaacccaaaa acttgcagat atagatttcc tttgaagaaa
    40741 cgactccata ggctaactgg cgtttctctt cggcttcttc tagcactacg ccccctctgt
    40801 tgactcttaa tattggttac caataaaagt aggaaaacag ggaagacgac catcaaataa
    40861 gaagcgtgca gaggctcttg tgaaaagaaa agtaaaatca aacctaaaat taccacaaga
    40921 cttgcaggaa ccgaaatgac gtatagttta aagggtttgg attgaaagag acctaaaaag
    40981 atacaaacca caaatcccaa accaagggac aacaagccat aaaaaaacat attctctaaa
    41041 attttagaag taaaatcaaa gcgaatactg tcaataggat aacgaatacc actaatcgca
    41101 tccccaaaac ttcctgttgc agcactatag taggcagttg gataaaagac aagtgaaaaa
    41161 cctaaagcca ctgcaagaaa ctgataaaac ccatgcgcaa agcgtctatg cccaaggtta
    41221 aagaccaaca agcctaaact cactacagca ataaacagga gcgatgataa gggagcaaag
    41281 aaaaatccgc ctgccaaagc tagcccaatc cgtacaaatc ccttatcatg gcttggattg
    41341 cttaggtaag ccgcaactaa actaaaggct gcgaataaga aaggaagcgc taaaagagtc
    41401 gcatagcctc caccaaaagc aagacctgta actagcatgt aaaaaatagt caccagatgt
    41461 ccagcttggt ctccttgctc tgtcaaggtg tccgctgatc taaaaaggaa aaatcctcct
    41521 gctaccaagg ctaaccactc aaagatggca aagaaaaatc cgccctgact cacgtaagtc
    41581 agcaaataat aaagcaaacc ttgacttcca taatagtcgc tgtaaatctt ccctgtctga
    41641 tgaagcgccc aacctgcata aaaatcctgc acttcttgtg cactcattaa gtcgagtaat
    41701 agcggtactc ctagagttat ccccgttaca agcgtactcc atagtaaaat tttcaccaaa
    41761 ggaagacgac ttgattcacg atgatgcgat tcttgttcga tttggtattc tagaggttca
    41821 cgattctcct tatgaacttc ttctactcta ccatacacac tcatatcgtt tctcctgttc
    41881 aatttatctg tcttagtata tcaaaaagtc ctaggattgt cagcttgcga tggctgtttg
    41941 agtgattttt tgcatagttt cacaaaggtt tcaatttccc gaaagcggtg taaatgtgtc
    42001 tgtttgaact caatcatatc attcacttct tccttagtta gcatgaattc ccctcctctt
    42061 tctttctatt cgtaaaagac aagaaaaata ggtctggttt gtatcctaag ttctagattt
    42121 cttataagat aggggcgaat agctgggcga tttcttttac aagcttttga taccagctcg
    42181 ttttgataga atgaggatag acttcctgag aatctgcaaa tatatttcga aaatctcggg
    42241 cgatttccct tatagaagga gttttataga gtaagactgc attttcataa tggtgtacca
    42301 agctccggta gtcgagattg attgtcccca ccaccgcaaa atcttcgtct accaacatct
    42361 gcttactatg aataaaacct ggactatact cataaatccg aacaccagca gaaagaaggt
    42421 cgggataagc tcctctcgtg actaactgaa tgaacttctt atctggtatg taaggggtga
    42481 taattcgaac atcgacccct ctcatagctg catttttgat tgtctctgtt aaatcataat
    42541 ctataatcaa ataaggtgtc gtaatataga ccgattctgt tgcttgattg attaaactct
    42601 gataaacttt tttccctacc tgcgctcgaa aaattggctt gggtccactt ccgtatggaa
    42661 tggttaaacc gtcactcggg atagaatgat tttctaaatg atattgatca aaatcactaa
    42721 tttctcctcg attaatgtac caagtggtca aaaataagcg tgtcagagct tttactgcta
    42781 gtccgtctaa gcgaattcca ctatccttcc aataaccaaa tctctcgacg tggttaatgt
    42841 actcatctgc cagattgatc ccaccagtat aggctatctg accatcaaca atcaatattt
    42901 ttctatgatc tctgttatta taagccactg tcaaacgagg aataacttta ttgaatttat
    42961 gggcctcgat gcccagctga cgaagtcgat gtgcataatc tcctgttaaa gtagccatac
    43021 agccgatatc atcatagagc atcttaacct ctacaccctg agctaccttt tgctctagta
    43081 tatctagtat gcgattccac atcaaacctt cttctataat gtaatattcc aagaaaataa
    43141 atttctcagc ctttttaaga tcttctacca tctttttcca catagcttct ccgttaggaa
    43201 aaaatgtaga ggcagtttga tcatagatgt cagcattggt atccatactc aataaggact
    43261 tgatgactcc ataagctgcc ttgtcacttt cttttaattt ctcttttagt agctggctat
    43321 ttgcttcttg gaaatgcata gagcctagct tcttcagttg tttgatttct tttttggaca
    43381 atcgcctttc accaaacatc agatagagca agggaccaaa tactggcaca aaggctacta
    43441 acaaccaggt taccttattc tcaggagtcg tattacggtt gactatcgaa atgattgtga
    43501 tgatactcag tagaatgagg acagtaatcc ataaaatggg agccatgcgt cctaaataaa
    43561 gaaagagacc aaaaacaaga caaagttcaa gtagcataat cgaaagacta aagccatact
    43621 tggacatcaa taattgaaat ttcctatatt tcatatcccc tccttgatag tttgaatgct
    43681 aaaaacaagt aattgatact agtataacgc aggtattcgg tagaaggcaa gtatttatga
    43741 ttattttcta ggtaaaagta aaaaggctga aaaatccagc cctttctact tgcatagtct
    43801 tatttagtta aaacgatttg gtccgatggg tctctatcca tatcatctac gacgatttga
    43861 ttaccgttta cagtgtaaat tttgacatca tcgccaataa tcatgcgttg atttgctgaa
    43921 tcaaatgtaa cctgtttgac tttctgatcc ccgtcagatt cgagctcagt ccatgtacca
    43981 gtcgttccag ttaccactaa agtgatacgg tctccgtcat cctgaccagt ataagtccca
    44041 tcaatatcgg tcggttgagc aacaggttgg ttttgtactg gagccgcttg attttggtta
    44101 cctcctgcat ttgcagtatt ggtattctgt tgagcaggct gttgaacctg ttgagctctt
    44161 tgtgaacaag ctactaagag actaaaactt gctagagaag caagagaaag tgtgaatctt
    44221 tttaatttca tgatgaattt cctttctgct accaatttag agaaattttc tctaaccagc
    44281 aattccccta gtataacaag ttcaaacaag ggggtcaatt tatctgctca cggtccagca
    44341 ggtagccccg tacttctgag ataaaataga gagaccctgt aacgaacagc aaatcctgag
    44401 catctgctct ttcttcaaaa tcgctgataa attctcggta agaagaaact atatcgtaac
    44461 ctgtcacatc cctttcgtcc aaagccccct gatagtcaaa gccggtcacc ttgagttcca
    44521 cctgaggcaa tttttcagtc aggtaaccta acatcccttg ataatccttc cgtttcaagg
    44581 ctccaaaaag gatttgagga cgataacctt cctgctcttt ttctttgata aactcaacca
    44641 agcgagtcaa ggcagggagg ttatgagcac catccaagta aatctgtggg cgaatacgct
    44701 ccaagcgacc agcccaatgg gtctgttcca aggcctttct tacagcctgt tcatcaacag
    44761 cttcctttcc ttctcccata aaaagaagaa aagtttgcaa cgccaaggct gcattctcct
    44821 gctgatagac tccttctaag cctatgttca gctgtgaaag atttagtaaa gagcttgaaa
    44881 aatcaccatt cagcattaaa aaatcttgac ctgcctgata aaggttaaca gctaaagatt
    44941 cggctttttt ctgacagaca agcctagctt ctggaggcaa tttcgcaatc actgccttct
    45001 taccagcctt gaaaatacca gctttctgct ctgcaattgc ttctagacta tcacccaagg
    45061 tttcttgatg gtcaagccca atggaggtga tgacagcaag ctctccagtt accacattgg
    45121 tcgtgtcaag taagccacca attcccactt ctaataaaac caaatccacc tcctgctccc
    45181 taaaataaag aaaagcaacc aaggtcagca attcaaaaaa ggacaactgg tcaggagttt
    45241 gcagaagcgt tttctccatc tccttgacct gatcagccaa acggataaag tctgcgtctg
    45301 ctataggttg cccattaatg caaattcggt cattgatgga tacgatatga ggggaggtaa
    45361 aggtcgcaac ttttttgcca tgccccataa ataattccct cataaaagca atggtagatc
    45421 ctttcccatt agtccctgtt acgtggataa tagggtaaga ctgctcagga tttcctaaca
    45481 aatccaccgc ttgctgtatt cggcccaaac ctgatcgaaa attcaaacca atccgactat
    45541 gaagccattc ttctacttca aacatacaca tctccttgac aaaagtccaa tcaattatcg
    45601 cattaaagta tagttactaa taaaaacaag gccaggattt tcgtcccgac ctcttacctg
    45661 gttagctaat aactagctac tatgaatgtg aacgtgggct aaaaatatcc actagatgtt
    45721 ccaactcttc tcaatttcta ggagttgggg taaaaatgtt cactggacgt tccaactctt
    45781 ccccatttct gggagttggg ctgatacagt ctctcagact acctgcgttt ctaatttcta
    45841 gcgcagggct aaaaacgtcc cccggacgtt tttactcctc cataaagctg ttgaagactt
    45901 cttcaatcat gttccattcg tcttctgagt cttctgggat tggttgcaat tcgccttctg
    45961 ttccatcttc gttttcgatg aatgagtaag cttggatttc aacttgtccg tcttcgtctt
    46021 cttctgcgtt aactggtact agaagaacat agtttttacc aaattcttct tttccatcaa
    46081 ttgtcaaaag gatttcaaac aaggtttcat ttccttgctc atctactagt gtgattagtt
    46141 cacgttcttc gtggtcgtgg ttatgatcgt gtgacatagc ctctccttta tattaaaatt
    46201 ttctatctaa ataattttgt aaaatcagct gagctgctaa cttatcaatg actttcttgc
    46261 gcttattgcg actgatatct gcttgttcaa tcaacatgcg ctcagcagcc actgttgtca
    46321 agcgttcatc ctgatagtct actggtaaac caaaaaactc ttctagcttt gctccgtagg
    46381 cttgactagc ttctacgcgc ggtccacttg tattgttcat gtttttaggc aagcccacta
    46441 caaatcgttc caccttgtaa gtatcaacca attccttaac gcggtcaaaa ccaaattggc
    46501 cttgttcttc atttatctgg atgatttcaa gcccttgagc tgtaaaacca agcggatcgc
    46561 taatcgccac ccctaccgtt tttgaaccga cgtccaatcc cataattctc ataggttata
    46621 gatcgactcc ttgtcctttg aggtagtagc gaaccaattc ctcaacgatt tcatcacgct
    46681 catacttacg gatttgattt cgtgcattat tataacgagg aacgtaggca gggtctccac
    46741 tcaatacgta acctacgatt tggttaattg ggttgtaacc cttatcgttc aacgaagcat
    46801 aaacatctgt caaagtttcg ctaatttctt ttttattgga atcgtccaat ttaaaacgta
    46861 ctgtttcttc agtaaatccc attctaacac cctctttcct tagaatagta ccattatagc
    46921 ataattcctt accttctaca attcaggcag tctatttatt tggattttct actgttctgt
    46981 cgcaccattt gccaatctgt ctgaaatata gttgcttggt tcatttttca aaagattttc
    47041 caaaccaata ttcttcagat gttccaactg ggaagccttc ttgacatcca gaacttgaaa
    47101 atcaaaacta gtcgttgttt gaagttccgt tgcgctcaat agttttgttt caagtttgaa
    47161 acctaccaat ttacgagctt caatgataga cttatccttc tcctccgctt caagaagagc
    47221 tttttgagtt tcttccactc catgttggtc aatataagtc ttcaactcat cagaaactgg
    47281 acgtttttgt tgaatcgtta agctcaaaaa agtcttgtcc ttgtatgtaa tggtttgagt
    47341 ttgctggcta ccatcatctg acttgggcaa gaccaaagtc ttagttacaa ctgtattctt
    47401 ctcagcattt tcaataactg gcaatgccga ctgaagcgta tctttttctg tttttgtagc
    47461 tggtccagtt tcttttttct gtccgcaacc aaccaggaca aaaaggaaag ctagactaac
    47521 aagaactatt tttttcattt ctttcttctt tctttttgaa attaaaatag aataagactg
    47581 ggaagtgctc ccagccttga tgtttataga gctgcacgca aacgtgcttc tgcattttct
    47641 acattacgga cagagcgtgg taggaaggca cgaatatcgt cttccttgta gccaacttgc
    47701 aggcgttttt catctacaag gattgggctc tttaaaattc tcggtgtttc cataatcaga
    47761 ttgagaactt cattgacact caaatcttca atatccactc caagggcttt ggcatagcga
    47821 tttttagacg aaacgatgct ggctattccg ttatctgttt tggttagaat atccagtaat
    47881 tcttctctcg taattccttc tttaccaagg ttttgttctt tataacttaa ctggtgggca
    47941 ttgagccagg tttttgcttt tttacagcta gtacaacttg agactgtata aattttaatc
    48001 atgtacctac ccctttcgct acatgttact atcagtttag tctattatac cataaaaaac
    48061 atccgacttg cgacctattt ttaattt
//
LOCUS       DAVKAU010000012        47130 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVKAU010000012 DAVKAU010000000
VERSION     DAVKAU010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47130
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.012"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..681
                     /gene="cbpA"
                     /locus_tag="VWX48_000781"
     CDS             <1..681
                     /gene="cbpA"
                     /locus_tag="VWX48_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpA"
                     /protein_id="HEU9171436.1"
                     /translation="QPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNG
                     AMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNGSWYYLNA
                     NGDMATGWFQYNGSWYYLNANGDMATGWLQYNGSWYYLNSNGAMVTGWLQNNGSWYYL
                     NANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNGSGALAVNTTVDSYRV
                     NANGEWVN"
     gene            complement(911..1891)
                     /gene="dusB"
                     /locus_tag="VWX48_000782"
     CDS             complement(911..1891)
                     /gene="dusB"
                     /locus_tag="VWX48_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU9171437.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1878..2750)
                     /gene="hslO"
                     /locus_tag="VWX48_000783"
     CDS             complement(1878..2750)
                     /gene="hslO"
                     /locus_tag="VWX48_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU9171438.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2915..4342
                     /locus_tag="VWX48_000784"
     CDS             2915..4342
                     /locus_tag="VWX48_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9171439.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            4501..6009
                     /gene="glpK"
                     /locus_tag="VWX48_000785"
     CDS             4501..6009
                     /gene="glpK"
                     /locus_tag="VWX48_000785"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU9171440.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEIDD"
     gene            6156..7982
                     /gene="glpO"
                     /locus_tag="VWX48_000786"
     CDS             6156..7982
                     /gene="glpO"
                     /locus_tag="VWX48_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU9171441.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARNLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            8052..8756
                     /locus_tag="VWX48_000787"
     CDS             8052..8756
                     /locus_tag="VWX48_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9171442.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            9053..9256
                     /locus_tag="VWX48_000788"
     CDS             9053..9256
                     /locus_tag="VWX48_000788"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171443.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(9343..9951)
                     /locus_tag="VWX48_000789"
     CDS             complement(9343..9951)
                     /locus_tag="VWX48_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171444.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            10988..12265
                     /gene="ltrA"
                     /locus_tag="VWX48_000790"
     CDS             10988..12265
                     /gene="ltrA"
                     /locus_tag="VWX48_000790"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEU9171445.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLPTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            12722..13433
                     /locus_tag="VWX48_000791"
                     /pseudo
     CDS             12722..13433
                     /locus_tag="VWX48_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            13628..13878
                     /locus_tag="VWX48_000792"
                     /pseudo
     CDS             13628..13878
                     /locus_tag="VWX48_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
     gene            14192..14323
                     /locus_tag="VWX48_000793"
     CDS             14192..14323
                     /locus_tag="VWX48_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU9171446.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            14344..15894
                     /gene="dltA"
                     /locus_tag="VWX48_000794"
     CDS             14344..15894
                     /gene="dltA"
                     /locus_tag="VWX48_000794"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU9171447.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            15891..17135
                     /gene="dltB"
                     /locus_tag="VWX48_000795"
     CDS             15891..17135
                     /gene="dltB"
                     /locus_tag="VWX48_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU9171448.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            17149..17388
                     /gene="dltC"
                     /locus_tag="VWX48_000796"
     CDS             17149..17388
                     /gene="dltC"
                     /locus_tag="VWX48_000796"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU9171449.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            17381..18649
                     /gene="dltD"
                     /locus_tag="VWX48_000797"
     CDS             17381..18649
                     /gene="dltD"
                     /locus_tag="VWX48_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU9171450.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMRHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            18804..19244
                     /gene="adcR"
                     /locus_tag="VWX48_000798"
     CDS             18804..19244
                     /gene="adcR"
                     /locus_tag="VWX48_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU9171451.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            19244..19948
                     /locus_tag="VWX48_000799"
     CDS             19244..19948
                     /locus_tag="VWX48_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9171452.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            19941..20747
                     /locus_tag="VWX48_000800"
     CDS             19941..20747
                     /locus_tag="VWX48_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9171453.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTISTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            20757..22262
                     /gene="adcA"
                     /locus_tag="VWX48_000801"
     CDS             20757..22262
                     /gene="adcA"
                     /locus_tag="VWX48_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU9171454.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDAKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(23424..24197)
                     /locus_tag="VWX48_000802"
     CDS             complement(23424..24197)
                     /locus_tag="VWX48_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9171455.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            24373..25776
                     /locus_tag="VWX48_000803"
     CDS             24373..25776
                     /locus_tag="VWX48_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU9171456.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKEE
                     YGLCDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYFQKN"
     gene            25891..26529
                     /locus_tag="VWX48_000804"
     CDS             25891..26529
                     /locus_tag="VWX48_000804"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU9171457.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            26541..26981
                     /locus_tag="VWX48_000805"
     CDS             26541..26981
                     /locus_tag="VWX48_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU9171458.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSVSCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            26974..27405
                     /locus_tag="VWX48_000806"
     CDS             26974..27405
                     /locus_tag="VWX48_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9171459.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            27396..27866
                     /locus_tag="VWX48_000807"
     CDS             27396..27866
                     /locus_tag="VWX48_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9171460.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            27891..28664
                     /locus_tag="VWX48_000808"
     CDS             27891..28664
                     /locus_tag="VWX48_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9171461.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            28661..29461
                     /locus_tag="VWX48_000809"
     CDS             28661..29461
                     /locus_tag="VWX48_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9171462.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            29520..31814
                     /locus_tag="VWX48_000810"
     CDS             29520..31814
                     /locus_tag="VWX48_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9171463.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            31824..34940
                     /locus_tag="VWX48_000811"
     CDS             31824..34940
                     /locus_tag="VWX48_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9171464.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDSNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGVRYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSSAIPLSLAEVEVYGSKRTPKKLSNIALAKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            35023..36789
                     /locus_tag="VWX48_000812"
     CDS             35023..36789
                     /locus_tag="VWX48_000812"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU9171465.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            36935..38086
                     /locus_tag="VWX48_000813"
     CDS             36935..38086
                     /locus_tag="VWX48_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU9171466.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            38231..39115
                     /locus_tag="VWX48_000814"
     CDS             38231..39115
                     /locus_tag="VWX48_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9171467.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            39559..39811
                     /locus_tag="VWX48_000815"
                     /pseudo
     CDS             39559..39811
                     /locus_tag="VWX48_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            39799..40089
                     /locus_tag="VWX48_000816"
     CDS             39799..40089
                     /locus_tag="VWX48_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171468.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(40493..41824)
                     /locus_tag="VWX48_000817"
     CDS             complement(40493..41824)
                     /locus_tag="VWX48_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU9171469.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(41846..43357)
                     /locus_tag="VWX48_000818"
     CDS             complement(41846..43357)
                     /locus_tag="VWX48_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU9171470.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(43568..44515)
                     /gene="arcC"
                     /locus_tag="VWX48_000819"
     CDS             complement(43568..44515)
                     /gene="arcC"
                     /locus_tag="VWX48_000819"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU9171471.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(44680..45696)
                     /gene="argF"
                     /locus_tag="VWX48_000820"
     CDS             complement(44680..45696)
                     /gene="argF"
                     /locus_tag="VWX48_000820"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU9171472.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(45754..46983)
                     /gene="arcA"
                     /locus_tag="VWX48_000821"
     CDS             complement(45754..46983)
                     /gene="arcA"
                     /locus_tag="VWX48_000821"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU9171473.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
BASE COUNT        14461 a         8425 c        10106 g        14138 t
ORIGIN      
        1 caaccagctc cagcaccaaa aacaggctgg aaacaagaaa acggtatgtg gtacttctac
       61 aatactgatg gttcaatggc aacaggatgg ctccaaaaca atggttcatg gtactacctc
      121 aacagcaatg gcgctatggc gacaggatgg ctccaaaaca atggttcatg gtactatcta
      181 aacgctaatg gttcaatggc aacaggatgg ctccaaaaca atggttcatg gtactacctc
      241 aacgctaatg gttcaatggc gacaggatgg ctccaataca atggttcatg gtactacctc
      301 aacgctaatg gtgatatggc gacaggatgg ttccaataca atggttcatg gtactaccta
      361 aacgctaatg gtgatatggc gacaggatgg ctccaataca atggttcatg gtactacctc
      421 aacagcaatg gtgctatggt aacaggatgg ctccaaaaca atggctcatg gtactacctc
      481 aacgctaacg gttcaatggc aacagattgg gtgaaagatg gagatacctg gtactatctt
      541 gaagcatcag gtgctatgaa agcaagccaa tggttcaaag tatcagataa atggtactat
      601 gtcaatggct caggtgccct tgcagtcaac acaactgtag atagctatag agtcaatgcc
      661 aatggtgaat gggtaaacta aacctaatat aactagttaa tactgacttc ctgtaagaac
      721 tctttaaagt attccctaca aataccatat cctttcagta gataatatac ccttgtagga
      781 agtttagatt aaaaaataac tctgtaatct ctagccggat ttatagcgct agagactacg
      841 gagttttttt gatgaggaaa gaatggcggc actcaagaga ctctttaaga gagttacggg
      901 ttttaaacta ttaagccttc tccaattgca agagagcttc aatctctgcc agggtgctag
      961 cttgcgaaat ggctccacgg agtttggcag cgccagatgt tccacggagg tagtgaggag
     1021 cgaggccacg gaattcacga actgcgacgt tttctccttt gaggttaatc aatcgtttca
     1081 agtgttcgta ggcgatcttc atcttgtctt caaaggtcaa atcaggtagg atttctcctg
     1141 tttcaaagta atggttgatt tggttgaaga ggtaaggatt tcccatggca gctcggccaa
     1201 tcatgactgc gtcagcacca acttcttcga tgcgttgctt ggcttcttgg acagtacgga
     1261 tatcaccgtt ggcgatgaat ggaatcttgg ttagagcttg ggcaaccttg taaagggtct
     1321 caaggtctgc gtggccagta tacatttgtt cacgggtacg gccatgcatg gcgagggcag
     1381 aaacacctgc agcctcagca gcgagggcat tttctactgc cagagatggg tccgcccagc
     1441 cggtacgcat tttgacagta agtgggatat caaggacaga ctggaccttg ttgatgatag
     1501 agtagatctt gtcaggatcc ttgagccaca tagcaccagc ttcgttcttc acgattttgt
     1561 tgacagggca gcccatgttg atatcgacga tatcggtctt agtgttttct tggataaatt
     1621 ctgctgcgcg tgctaggctg tcttcatcgc taccaaaaag ttggatagag acagggtttt
     1681 cgccctcatc gatatgaagc atgtgcaggg ttttttcgtt gttgtattgg attcccttgt
     1741 cagagaccat ttccattaca acgagtccag ctccgagctc ttttgcgatg gtacgaaagg
     1801 ctgagttggt cacgccagcc ataggcgcta aaacggtacg attgggaatc tcaacattgc
     1861 caatcataaa aggtgtatta agatttgtca cgaatgagtt cctccaggtc cttttcatca
     1921 aagttgtaag tagtttggca gaattgacaa gtgatttcta ccccgtggtc ttcctctttc
     1981 atttcctgta agtctgagct tggaaggctg gcaagagcgt tcataaagcg ttcatggcta
     2041 cagtcacatt ggaaacggat ttcttcttca gaaagacgct tgtaggcttc gtccccgtag
     2101 atagccttga ggagggcttc gatatggtcg tcgctttcga gaagagtaga gatagctggc
     2161 atttcttgga tgcgtttttc aaagcgagca atctcttctt tcttggctcc tggcaagact
     2221 tgaactagga aaccacctgc aatcttgacc ttgtcttcct cgtccaaaag gacattgagg
     2281 ccgaccgctg aaggcgtttg ttggctttca gtaaggtaaa aggcaaggtc ttcaccgatt
     2341 tctccagaga tgaggggagt tatagagttg taaggatttc cagtaccgta gtctgtgata
     2401 acgaggaatt gaccatttcc aacaaaaggt ccgactagga cttcaccagt cgcagtcttt
     2461 ttgatgtcaa caccaggatt ttgaacgtag cctttgacgt tccccttggt atcagcgacg
     2521 gtgataatag cacctagaga gctagatccc aacaccttaa ctgtaagttt ggtatttcct
     2581 ttttcattgg ctgcgagaat ctggctagcg ataagagttc gaccaagcgc tacagttgag
     2641 ctagcttggg tttgatgttt ttcttgagca gtgcggacgg tttcagtgct atcaaggaca
     2701 aaagcacgaa aggctccgct ttctgatata gttttaataa ttttatccat agctactatt
     2761 ttagcataaa aatgcccaaa gggggagccg tgtgtttact gattttcagg ataatggacc
     2821 aggaaatcag catgaaaata aaaagagaaa cagattattt cagcatttgt aagatttatg
     2881 ctatgcttaa ggtagaaaat gaaagggata acaaatgtat ttaggagatt tgatggagaa
     2941 agccgagtgt ggtcaatttt caatcctttc ctttctatta caagagtctc agacgaccgt
     3001 caaggctgta atggaagaaa caggattttc aaaagcaacc ctaaccaaat atgtcaccct
     3061 gctcaatgac aaggctttgg atagtggctt agaactgact attcactcag aagatgaaaa
     3121 tctgcgtctg tctatcggtg cagctaccaa ggggagagat attcggagct tgtttttgga
     3181 gagtgctgtt aaataccaga ttttggttta tcttctctac caccaacagt ttttagccca
     3241 tcagctggct caagaattgg tgattagcga ggctacgctt ggtcgtcact tggctggttt
     3301 aaatcagatt ttgtcagaat ttgatttatc catccaaaat ggacgttggc gaggtccaga
     3361 gcatcagatt cgctatttct atttctgtct tttccgaaag gtctggtcga gtcaggaatg
     3421 ggaaggtcac atgcagaaac cagagagaaa acaggagatt gccaatttag aggaaatctg
     3481 cggtgcaagt ttgtctgtgg ggcagaaatt ggacttggtt ctctgggctc acatcagtca
     3541 acaacgtctt cgggtcaatg cttgtcagtt tcaagtcata gaagagaaaa tgcgagggta
     3601 ttttgacaat atcttttatc ttcgtttgct gagaaaggtt ccgtcctttt ttgctgggca
     3661 acatattcca ctaggagttg aggatggtga gatgatgata ttcttctctt ttctcctatc
     3721 tcatcgcatt cttcctcttc atactatgga gtatattctt ggttttggag ggcagttggc
     3781 agatttactg acgcaattga ttcaagaaat gaagaaggag gaactattgg gggattatac
     3841 agaggaccat gtcacctatg aactcagtca gctttgtgct caagtctatc tctataaggg
     3901 ctatatttta caggatcgtt acaagtacca gttagagaat cgtcatccat atttactgat
     3961 ggaacatgat tttaaagaga cagcagagga gatttttcat gctctacctg cttttcaaca
     4021 ggggacagat ttagataaga agattctctg ggaatggctc cagttaatcg aatatatggc
     4081 tgaaaacggt ggccagcata tgcggattgg tctggatttg acatctggtt ttcttgtctt
     4141 ttcaaggatg gcagccattt tgaaacggta tttagaatac aatcgtttta ttaccattga
     4201 agcttatgac cctagtcggc attatgattt gctggttacc aataacccga ttcataagaa
     4261 ggaacagacc ccagtctatt atttaaaaaa tgacttggat atggaggatt tggcagggat
     4321 tcgtcagtta ttattcactt aaaaggcttg gttgttccag gtcttttttg tgaaattcac
     4381 acaatctcct cacgtttttt taaaaattaa aaaaagttga taaacaagaa agcgctttat
     4441 tttgtatact agtaagtgta aagaggaaac acctcaagat ctttatcagg aggacagtac
     4501 atgtcacaag aaaaatacat catggccatt gaccagggaa ctacaagttc tcgtgccatc
     4561 attttcaaca aaaaagggga aaaggttagc tcgagtcaaa aagagtttac ccagattttc
     4621 cctcaggcag gttgggttga gcacaatgcc aatgaaattt ggaactctgt tcagtcagtt
     4681 attgcgggtg ctttcattga aagtggtgtc aagccaaatc aaatcgaggc aatcgggatt
     4741 accaaccaac gtgaaacaac ggttgtctgg gataagaaaa caggacttcc tatctacaat
     4801 gctatcgttt ggcagtcacg ccagacagca cctttggctg agcaactaaa aagccaaggt
     4861 tatgtggaaa aattccatga aaagactggt ttgattattg atgcttactt ctctgctacc
     4921 aaggttcgtt ggattttgga tcatgtagaa ggtgctcaag agcgagcaga aaaaggggaa
     4981 ttgctctttg gtactatcga tacttggttg gtttggaaat tgactgacgg tgcggctcac
     5041 gtgactgact actcaaatgc agctcgtacc atgctttata acattaaaga actcaaatgg
     5101 gatgatgaga ttttggaaat ccttaacatt ccgaaggcta tacttccaga agttcgttct
     5161 aactccgaaa tctacggcaa gacagctcca ttccatttct acggtggaga ggtgccaatc
     5221 tcaggtatgg ctggggacca acaagcagcc ctctttggac agttggcttt tgagccaggt
     5281 atggttaaga atacttatgg aacaggctct ttcatcatca tgaatactgg ggaagagatg
     5341 cagttgtctg aaaacaacct cttgacaacc attggttacg gaatcaacgg taaggtttat
     5401 tatgccttgg aaggttctat cttcatcgca ggaagtgcta ttcagtggct tcgtgacggt
     5461 cttcgcatgg ttgaaaattc accagaatct gaaaaatacg ctcgtgattc tcacaacaac
     5521 gatgaagttt atgtcgttcc agcctttaca ggtctaggcg ctccatactg gaaccaaaat
     5581 gctcgtggtt ccgtctttgg tttgactcgt ggaacaagca aagaagactt tatcaaggcg
     5641 actttgcaat ctattgctta tcaagtgcgt gacatcatcg acaccatgca agtggatact
     5701 cagaccgcca ttcaagtact gaaggtggat ggtggtgcag ccatgaacaa cttcctcatg
     5761 cagttccagg cggatatttt aggcattgat attgcacgtg ctaaaaactt ggaaacaaca
     5821 gctctaggag cggccttcct agcaggtttg tcagtagggt actggaaaga cttggacgag
     5881 ttgaaactct tgaacgagac aggagaactc tttgagccat ctatgaacga atctcgcaag
     5941 gaacaactct ataagggctg gaagaaggct gtgaaagcaa ctcaagtctt tgcggaaatc
     6001 gatgactaat actcaatgaa aatcaaagag caaactagga agctagccgc aagctgtact
     6061 tgagtacggt aaggcgacgc tgacgtggtt tgaagagatt ttcgaagagt ataatactgg
     6121 cagaataaag cgatttagtt agaaagtgtg taaatatgga attttcaaag aaaacacgtg
     6181 aattgtcaat taaaaaaatg caggaacgca ccctggacct cttgattatc ggtggaggaa
     6241 tcacaggagc tggtgtagcc ttgcaggcgg cagctagcgg tcttgagact ggtttgattg
     6301 aaatgcaaga ctttgcagaa ggaacatcta gtcgttcaac aaaattggtt cacggaggac
     6361 ttcgttacct caaacaattt gacgtagaag tggtctcaga tacggtttct gaacgtgcag
     6421 tggttcaaca aatcgctcca cacattccaa aaccagaccc aatgctctta ccagtttacg
     6481 atgaagatgg agcaaccttt agcctcttcc gtcttaaagt agccatggac ttgtacgatc
     6541 tcttggcagg tgttagcaac acaccaactg cgaacaaggt tttgagcaag aaagaagtct
     6601 tggaacgcca gccaaacttg aagaaggaag gcttggtagg aggtggagtg tatcttgact
     6661 tccgtaacaa cgatgcgcgt ctcgtgattg aaaacatcaa acgtgccaac caagacggtg
     6721 ccctcattgc caaccacgtg aaggcagaag gcttcctctt tgacgaaagt ggcaagatta
     6781 caggtgttgt agctcgtaat cttttaacag accaagtatt tgaaatcaag gcccgtctgg
     6841 ttattaatac aacaggtcct tggagtgata aagtacgtaa tttgtctaat aagggaacgc
     6901 aattctcaca aatgcgccca actaagggag ttcacttggt agtggattca agcaaaatta
     6961 aggtttcaca gccagtttac tttgacacag gtttgggtga cggtcgtatg gtctttgttc
     7021 tcccacgtga aaacaagact tactttggta caactgatac agactacaca ggtgatttgg
     7081 agcatccaaa agtaactcaa gaagatgtag attatctact tggcattgtc aacaaccgct
     7141 ttccagaatc caacatcacc attgatgata tcgaaagcag ctgggcaggt cttcgtccat
     7201 tgattgcagg gaacagtgcc tctgactata atggtggaaa taacggtacc atcagtgatg
     7261 aaagctttga caacttgatt gcgactgttg aatcttatct ctccaaagaa aaaacacgtg
     7321 aagatgttga gtctgctgtc agcaagcttg aaagtagcac atctgagaaa tatttggatc
     7381 catctgcagt ttcacgtggt tcgagcttgg accgagatga taatggcctc ttgacccttg
     7441 ctggtggtaa aatcacagac taccgtaaga tggctgaagg tgctatggag cgcgtggttg
     7501 acatcctcaa agcagaattt gaccgtagct ttaaattgat caattctaaa acttaccctg
     7561 tttcaggtgg agaattgaac ccagcaaatg tggattcaga aatcgaagcc tttgcgcaac
     7621 ttggagtttc acgtggtttg gatagcaagg aagctcatta cctagcaaat ctttatggtt
     7681 caaatgcacc gaaggtcttt gcacttgctc acagcttgga acaagcgcca ggtcttagct
     7741 tggcagacac cttgtccctt cactatgcaa tgcgcaatga gttgactctt agcccagttg
     7801 acttccttct tcgtcgtacc aatcacatgc tctttatgcg tgatagcttg gatagtatcg
     7861 ttgagccaat tttggatgaa atgggacgat tctatgactg gacagaagaa gaaaaagcaa
     7921 cttaccgtgc tgatgtcgaa gcagctctcg ctaacaacga tttagcagaa ttaaaaaatt
     7981 aagaaaaaat aaaagaggtg gagggcagca ttccttgtcg cccgtccctt ctttttaatg
     8041 gagacagaaa gatgatgaat gaattatttg gagaatttct agggacttta atcctgattc
     8101 ttctaggaaa tggtgttgtt gcaggtgtgg ttcttcctaa aaccaagagc aatagctcag
     8161 gttggattgt gattactatg ggttggggga ttgcagttgc ggttgcagtc tttgtatctg
     8221 gcaagctcag tccagctcat ttaaacccag ctgtgaccat cggtgtggcc ttaaaaggtg
     8281 gtttgccttg ggcttccgtt ttgccttata tcttagccca gttcgcaggg gccatgctgg
     8341 gtcagatttt ggtttggttg caattcaaac ctcactatga ggcagaagaa aatgcaggca
     8401 atatcctggc aaccttcagt actggaccag ccatcaagga tactgtatca aacttgatta
     8461 gcgaaatcct tggaactttt gttttggtgt tgacaatctt tgctttgggt ctttacgact
     8521 ttcaggcagg tatcggaacc tttgcagtgg gaactttgat tgtcggtatc ggtctatcac
     8581 taggtgggac aacaggttat gccttgaacc cagctcgtga ccttggacct cgtatcatgc
     8641 acagcatctt gccaattcca aacaagggag acggagactg gtcttacgct tggattcctg
     8701 ttgtaggccc tgttatcgga gcagccttgg cagtgcttgt attctcactt ttctagttta
     8761 tactcttcga aaatcaaatt caaaccacgt cagcgtcgcc ttaccgtact caagtacagc
     8821 ttgcggctag cttcctagtt tgctctttga ttttcattga gtattagaaa acaattatgt
     8881 tgatagagct tgggcaagag cccaatttca gcaaaaaatg aagtaaatct tctcataata
     8941 aaacgcatca tatcaagcac gaaaattcca cgaggtcaac tacagtcaga aagctgaaca
     9001 acaagccaaa acgcccaaaa aaggcggcaa aaagcaagca cctgcaagca acgtgccgaa
     9061 atggtcaaat cctgattatg tcaacgaatt agacccaaaa atcgttgata tgctagtaga
     9121 atttcacaag tcacaaggca ctttggaaac tcccgaggcg caagcagaaa tcgcccaaaa
     9181 acgtgaagaa atcgagcaaa ggagagctga gcttgaggat aaaaaacaag agcttttgaa
     9241 ccgcttgaac aaatagagtt tcgcaagtat tatgcttaca aattacttga gcaattaact
     9301 aaaatataaa ccctgcctag atataaaggc agggtttata ttttagaaat tcacgtaggt
     9361 tgttacggtt tttacatacc cagtatagtt tgagtttcta tagtattcag tgataaactt
     9421 ccattttctt tgagcaacat ggatataagt acttgttatg tagtatggat atgggctttg
     9481 tgaatccaag taagactgat aagcttgtat accaaaatat gctccaccaa ttattgcacc
     9541 ccatggaccc cccaataaag cacctatcct accaatcata taactgattc cagcaccagt
     9601 catgaagtta gcgaatgtgt tagcttgttt attcccatgt attgtgttga cgtaattcca
     9661 aacattagga tcgtatgatc taaaagatat atttaggtcg atttcattct tttgataagc
     9721 catataaaat gccccattga tatagacgcc gtcagcacgt cgttcaatag tgtctacact
     9781 tccatctgga ttgacaacct caagaacttc atcgcttaaa atatttactt gcgtatctcc
     9841 gaaccgcact gatgagccat tctcaaactg agcctcacca gatacaactt tagagtttgc
     9901 cgataagcta tcatcagcaa aaacaacaag cgacggggaa atgctagaca tacagaaaac
     9961 agacataact agcaaacaca tgcatttaaa catcttagac ataacggaaa ctcttttgta
    10021 tttttgattt ttttcaactt ttattataca ataaaaccaa ataaaaagaa agcggtaaca
    10081 atatgcttaa tgcgaaaatt ttttatatat ttttatgttt gatcgttatc gaaactacag
    10141 gcttgttgtt gttgaaaaga ggtctcgaaa tgggttattt agacacagaa gctattatcc
    10201 tcgcagtttt ttcatttgct ttttacaacc tatgttcatt cgcttgggtc tgctctacaa
    10261 taaaaaacaa taaaaaataa atagacgtat tttcaaaaaa aaaaaaaaag catatttata
    10321 ttagtaaaac gacgatttaa atcgtcgttt tttttgtagt acgacgggca tgtcgtatat
    10381 ctgaggtgta agtcctcggt gggcacctgc taccggtgaa cccaatagcg attcccaagc
    10441 ctgactatcg tgaggtagcg gggagaggaa gagatagcga aatcgtggct ctacgaacag
    10501 gaacgtgata gcaaggcgta tatagcggat aaggaggctt caaactctaa agtccaaaaa
    10561 ggtagtcgta acctatatgt gtaaatcacg agagtaattg aattcggact aaggtttgtg
    10621 tgaaaaagat aaatctttct agagtctaaa gactctgcgt cagatttcct atttttactg
    10681 taacctttta acgtcctcat atcttgtata aacgaggaaa gatgtacgac ttatcccgtg
    10741 aggtttcatg agcgctgaaa gcgtagtaac aacgaatcat gagaagtcag ccgagcccat
    10801 agtagtgagg aaacttccgt aatggaagtg gagcgaaggg gtgaacaact aatcgaagta
    10861 atcctacttc acttgtgtct gtaaaacgaa cggtctgata gaactggact ctgtcacgta
    10921 ttgactagat gaaggttcac caatataaga tgtccctcag gcaccaaaac aagaaaggaa
    10981 tacgcacatg tcaaaattgc tagataagat attatcacgc gaaaatatgc tggaagccta
    11041 caatcaagta aaatccaata aaggctcagc tgggattgat ggaatgacta tcgaagagat
    11101 ggataattat ctcagacaaa actggcgctt gactaaggaa ctgataaaac agagaaaata
    11161 taagcctcaa ccagttctta aagttgagat acctaaacca gacggcggca tccgtcaact
    11221 aggaattcca acagttatgg atagaatgat tcaacaggcc attgtccaag tcatgagccc
    11281 catttgtgaa ccccatttct cagatacgag ttatggtttc agaccaaata ggtcatgtga
    11341 aaaagctatc atgaagctct tagaatactt aaatgacggc tatgagtgga tagtggatat
    11401 agacctagag aaatttttcg atacagttcc tcaagataga ttgatgtcct tagtacataa
    11461 cattatcgaa gacggagata cggaatcctt gattcgtaag tatcttcatt caggtgttat
    11521 cattaatggt caacgttata aaacactagt tggtacacca cagggaggaa atttatctcc
    11581 tctcttatcc aatatcatgc ttaatgaatt ggacaaggaa ttagaaaaga ggggacttcg
    11641 atttgtgcgc tacgcagatg attgtgtgat tacggtcgga agcgaggcag cctctaagcg
    11701 tgtgatgtat tcagtcagtc gttttattga gaaacggcta ggtttgaaag taaacatgac
    11761 caagactaag attaccagac caagagagtt gaaatatcta ggttttgggt tctggaaatc
    11821 atcagatggt tggaaaagcc gtccccatca agatagtgtt cggagattta agtttaaatt
    11881 gaagaaacta acacagagga aatggagtat agacctaaca agacgtattg agcaactgaa
    11941 tttgtctatt cgaggatgga taaactattt ctcattggga aatatgaaaa gtatagtcgc
    12001 cagcatagat gagcgcttgc ctactcgcct acgagtgatt atctggaagc aatggaagaa
    12061 gaaatcgaga cgattatggg gattgcttaa gttaggagtt cctaaatgga tagcagataa
    12121 ggtatctggc tggggcgacc attatcaatt agtagctcag aagtcggtac ttaaacgtgc
    12181 tatatcaaaa ccagtcctgg aaaaacgtgg actggtttcg tgtttggatt attaccttga
    12241 acgacatgcg ttaaaagtta gttgaaccgc cgtatgccga acggcacgta cggtggtgtg
    12301 agaggggcta gagattatcc tctactcgat taactcccct gaaatttatt ttaattatgc
    12361 aaatttcacg tatttttgat gctgagacga cgatcctggg aacttttcag atattttttt
    12421 gactatctaa atctatcatt agaaaagctt agagcgccaa aggatttgag cgtttttctg
    12481 atttttaaga ctttttccca gtctcttttt cgattgaaga tgtaattatt ctactaacta
    12541 actaacttct tagtactagc caacaacgat aatcataatt cctcctaaaa ttaggaataa
    12601 taaaggcaat agtttttgtt ttttcatgta aaaaacctca cttttgtttt ctgctatttt
    12661 atgctaaaat attaaaaatc aaatttaatt ccaaagtttg taactaaagg gggagcgcta
    12721 catgtctaat tcatttgtca agttgttagt ctctcaatta tttgcaaatt tagcagatat
    12781 tttctttaga gtaacaatca ttgctaacat atacattatt tcaaaatcag taattgccac
    12841 atcactagtt cctatcttaa taggaatatc ctcttttgtt gcgagtcttt tagttccgtt
    12901 ggttactaaa aggttagcgc taaatagggt tttatcttta tctcaatttg gaaagactat
    12961 attattggcg atactggtag gaatgtttac cgtaatgcaa tccgtagcgc ctttggtgac
    13021 ctatctattt gttgttgcaa tttccatact agatggtttt gcagcacccg tttcctatgc
    13081 tattgtgcca cgctatgcga ccgatttggg taaggctaat tcagccttat caatgactgg
    13141 tgaagctgct caattgatag gttggggatt aggtggactc ttgtttgcaa caattggtct
    13201 gttacctacc acgtttatca ttttagtctt gtatatcatt tctagctttc tgatgttatt
    13261 tcttcctaac gctgaagtgg aggtgttaga gtcagaaact aatcttgaaa ttttgctcaa
    13321 aggttggaag ttagttgcta gaaatcctag attaagactt tttgtatcag caaatttatt
    13381 ggaaattttt tcaaatacga tttgggtttc ttccattata cttgtttttg taacggagtt
    13441 attaaataaa acggaaagtt actggggata ttctaataca gcatactcta ttggtattat
    13501 aattagtggc ttaattgctt ttaggctatc tgaaaagttc cttgctgcta aatgggaaag
    13561 tattcttttt cctcttgtag ctatggcaat agtgacactg actattctat attttccaaa
    13621 cgcacagatg tttttattat tttcagcttt agttggtatg ttatcgcaac taaaagaagt
    13681 tcctgaaagt gtatttcttc aggaaacagt agaggaaaat catttagtta atgtctattc
    13741 cgttcttgaa gtgatttcta cattagcatt ttcagtattt gttttgctaa tgagctatat
    13801 tactgatttt ggctatcagc catttgtctg atgatagaag ctattttaat ttatatcaga
    13861 cgagattatt ttaaatgaga gagtggttaa aaagtcttta aaaatcagaa aagcgcatag
    13921 tatcaggtgt tgaaaaaact tgatattgtg tgttttatta tgggaagatt tacttcattg
    13981 tctcctgaaa tggagttttg aagcagaatc actctatttg aaaatataca tagaaaaacc
    14041 gcataatcct taaaataagc tgaaatctat tggaaacata cggtaaacaa ttgaaaagat
    14101 actatataaa gtggtacaat ggtagaagaa taagctagta agaatcactc ttattttagc
    14161 gaaaaattac agaaatgaat ggtttttctt gatgaaacag agaaaagaat tgtacctctt
    14221 tcttggtagg acagccttgt attttcttat ctttctaggg ctgctttact tctttagcta
    14281 tcttggtcag ggtcaaggaa gctttatcta taatgaattt taacttgaag gagaatccct
    14341 attgtgtcaa ataaaccaat agcagatatg attgaaacca ttgagcattt tgctcagaca
    14401 cagcctagct atcctgtcta taatgttttg gggcaggaac acacttatgg cgatttaaag
    14461 gctgattcgg atagtttggc tgcagtcatt gaccaactag gcttgcctga gaagtctcct
    14521 gtggttgttt ttggtggcca agaatatgaa atgttggcaa cctttgtagc gctgactaag
    14581 tcaggtcatg cctacattcc aattgatagc cattcggcct tggagcgagt ttcagctatt
    14641 ttagaagtag cagagccaag cttgattatt gccatttcag cctttccctt ggagcaggtt
    14701 tctacaccaa tgataaatct agctcaggtt caagaagcct ttgcccaagg gaacaactat
    14761 gaaatcacgc atccagtcaa gggagatgat aattactaca ttatctttac ttctggtacg
    14821 actggtaagc ctaagggagt gcagatttca catgataatc tcctcagctt tacaaactgg
    14881 atgattacgg ataaggaatt tgcgacaccg agtcgtccgc aaatgctggc acaaccacct
    14941 tattcttttg acttgtctgt catgtattgg gcaccgacct tggcacttgg tggtacgctt
    15001 ttcactcttc cttcagtcat cactcaggac tttaagcaac tctttgcggc tatcttttca
    15061 ttgccaatcg ctatctggac atcaacacca tcctttgcag atatggccat gttgtctgaa
    15121 tacttcaaca gtgagaaaat gcctggaatc acgcatttct actttgatgg tgaagaattg
    15181 acggtcaaaa cagctcaaaa actgcgcgag cgtttcccaa atgcccgtat catcaatgct
    15241 tacggcccaa cagaagcgac agtagctctg tcagcagttg ccgtgacaga cgagatgtta
    15301 gcgactctca aacgcctacc aatcggctat accaaggctg attctccaac ctttatcatt
    15361 gacgaggaag gaaataaact gccaaatggc gaacagggag aaatcattgt ttctgggcca
    15421 gctgtttcaa aaggttatat gaacaatcct gaaaaaacag cagaagcctt ctttgagttt
    15481 gaaggtctgc cagcctatca cacaggcgat gtgggaacca tgacagatga gggcttgctt
    15541 ctctacggcg gacgcatgga cttccagatt aagtttaacg gttaccgcat tgagttagaa
    15601 gatgtctctc aaaacctcaa caagtctcgc tttatcgaat ctgctgtcgc agtaccgcgc
    15661 tataacaagg accacaaggt acaaaatcta ttggcttatg tcatcttaaa agacggtgtt
    15721 cgtgagcagt ttgagcgaga tatcgatatt accaaggcca tcaaggaaga cctgacagac
    15781 atcatgatgt cctatatgat gccatctaaa ttcctttacc gagacagttt gccactaact
    15841 ccaaatggaa agattgacat caaaggattg attaacgagg tgaataagag atgatggagt
    15901 tttttcaaca gcttcctcat ttagagccat atggcaatcc tcagtatttt gtttatgtga
    15961 ttgctgcaac cttgcccatc tttataggtc tctttttcaa gaaacgcttt gcctggtatg
    16021 aagtgttggt aagtctcttc tttattgtca ccatgttggt gggtggaaag accaatcaac
    16081 tagctgcctt gggtatttac ctttgctggg aaatattgct cctgcttttc tacaagcatt
    16141 atcgaaaaag caaggatggc aagtgggtct tctacttagt tagttttctg tccctacttc
    16201 cgattatctt tgtcaaggtg caaccagcta tcaatggaac gcagtctttg cttgggttct
    16261 tgggaatttc ttacctgacc tttcgttcgg ttgggattat catcgagctg agagatggag
    16321 tgattaagga ttttaccctc tgggaattcc tccgtttcct tctcttcatg ccaactttct
    16381 cgagtggtcc aatcgatcgt tttaagcgat ttaatgaaaa ttatcaggcc attcctgagc
    16441 gagatgagtt gatggatatg ctggatgaat ctgtccgcta tatcatgcgg ggctttttgt
    16501 ataagtttat cctagctcat gttttaggag agaccttact acctcctctg aagaatttag
    16561 ccttgcagtc aggtggcttc tttaatctct atgccttggc agttatgtat acttttggtc
    16621 tggagctctt ctttgacttt gcaggttatt ctatgtttgc tttggccatc tcaaacttga
    16681 tgggaatccg tagccctatc aactttaaca agcccttttt atcaagggat ttaaaggagt
    16741 tttggaatcg ctggcatatg agtctgtcct tctggttccg tgactttgtc tttatgcgaa
    16801 tggtgatggt gttaaccaga aagaaagtct ttaaaaatcg taatgtaacc tcaagcatgg
    16861 cctacattgt aaatatgctg attatgggat tttggcatgg tgtgacctgg tactatatcg
    16921 cctatggact ctttcatgga ctaggcttgg tcatcaatga tgcctgggtt cgcaagaaaa
    16981 aaacgctcaa taaggaacgg aaaaaagcag ggaaggctgc cctacctgag aatcgctgga
    17041 ttcagttgct tggcatggtt gtcactttcc atgttgtcat gttgtcattc ttaatctttt
    17101 ctggattctt gaataatcta tggtttaaaa aataaaagga aataaaatat ggatatcaaa
    17161 tcagaagtta tcgaaattat tgatgagttg tttatggaag atgtttctga catgatggat
    17221 gaagatcttt ttgatgcagg tgtcttggat agtatgggaa cggttgagtt gattgtggag
    17281 attgagaacc gttttgacat tcgtgtccct gtaacagagt ttggtcgtga cgactggaat
    17341 acagctaata aaattatagc tggtattgtg gagctacaaa atgcttaaac gcttatggat
    17401 gatcttcgga ccggtcttga tagctggttt gttggttttt ctgctcattt tcttttatcc
    17461 tactgagatg cgtcataatc taggagctga aaagcgttca gcggtggcta ctactatcga
    17521 tagttttaag gagcgaagtc aaaaagtcag agcactatct gatccaaatg tgcgttttgt
    17581 tcccttcttt ggctctagtg aatggcttcg ttttgacggt gctcatcctg cggtattagc
    17641 tgagaaatac aatcgttcct accgtcctta tcttttagga caggggggag ctgcatcgct
    17701 taaccaatat tttggaatgc aacagatgtt accacagctg gagaataaac aagttgtgta
    17761 tgttatctca cctcagtggt tcagtaaaaa tggctatgat ccagcagcct tccagcagta
    17821 ttttaatgga gaccagttga ctagttttct gaaacatcaa tctggggatc aggctagtca
    17881 atatgcagcg actcgcttac tgcaacagtt cccaaacgta gctatgaagg acctggttca
    17941 gaagttggca agtaaagaag aattgtcgac agcagacaat gaaatgattg aattattggc
    18001 tcgttttaat gaacgccaag cctccttttt tggtcagttt tcggttagag gctatgttaa
    18061 ctacgataag catgtagcta agtatttaaa aatcttgcca gaccagtttt cttatcaagc
    18121 aatagaagat gttgtcaaag cagatgctga aaaaaatact tccaataatg agatgggaat
    18181 ggaaaattat ttctataatg agcagatcaa gaaggatttg aagaaattaa aggattctca
    18241 gaaaagcttt acctatctca agtcgccaga gtataatgac ttgcagttgg ttttaacaca
    18301 gttttctaaa tctaaggtaa acccgatttt tatcattcca cctgttaata aaaaatggat
    18361 ggactatgct ggtctacgag aggatatgta ccaacaaacg gtgcagaaga ttcgctacca
    18421 gttagaaagt caaggtttta ccaatatagc agatttttct aaggacggtg gggagccttt
    18481 ctttatgaag gacaccattc accttggttg gttgggttgg ttggcttttg acaaggcagt
    18541 tgatcctttc ctatccaatc ccacaccagc tccgacttac catctgaatg agcgcttttt
    18601 cagcaaagat tgggcgactt atgatggaga tgtcaaagaa tttcaataga taatataata
    18661 tagaagagtt caagaatgaa actagttttc acgttttttc ttgactcttt ttttgcttgt
    18721 gatataatta actggtaaac aaaatgtcaa agaatagtat ttttctctta aaaaagagaa
    18781 gtctaaaagg aaaggagtca gatatgagac agctagcaaa ggatatcgat gcttttttga
    18841 atgaggtgat tttgcaggcg gaaaatcagc atgaaatcct aataggtcat tgcactagcg
    18901 aggtggccct gaccaatact caggagcata tccttatgct cttgtcagag gaatctttaa
    18961 caaattcaga attggcccgt cgtctcaatg tcagtcaggc ggcagttacc aaggccatta
    19021 agtctttggt caaggaaggg atgttggaaa catctaaaga ttctaaagat gcgcgtgtga
    19081 ttttttatca gttgactgac ttggctcgtc caatcgctga ggagcaccac catcaccatg
    19141 agcatacact tttaacctat gaacaagtgg cgactcagtt tactccaaat gaacaaaaag
    19201 tgattcagcg gtttttgact gctttagtag gagaaatcaa ataatgagat atattacggt
    19261 agaggatttg tccttctatt atgataagga gcctgttctt gaacatatca attatagtgt
    19321 tgatagtggg gaatttgtta ccttgactgg ggaaaatgga gcggctaaga cgacgctcat
    19381 caaggctagt cttggaattc tgcaaccacg cattggaaag gtggctattt caaagacaaa
    19441 tacgcaaggt aagaaattga gaatagccta tcttcctcaa caaattgcca gttttaatgc
    19501 tggttttcca agtacggtct atgaatttgt caagtcgggt cgctatccga gaaaaggctg
    19561 gttccgtcgt ttgaatgctc atgatgagga gcatatcaag gccagtctgg actcagttgg
    19621 catgtgggaa catcgagaca aacgcttggg gtctctatct gggggacaaa agcagcgagc
    19681 ggtgattgcg cgtatgtttg cttctgaccc tgatgtgttt atcctagacg agccaacaac
    19741 ggggatggat gcaggaagta aaaatgaatt ttacgaactc atgcaccaca gcgcccatca
    19801 tcatggcaag gctgttttga tgattaccca tgaccctgaa gaagttaagg attatgcgga
    19861 tcgcaatatt catctagtcc gtaaccaaga ctcgccatgg cgttgtttca atgttcatga
    19921 gaatggccag gaggtgggcc atgcttagtt tattatctta cgactttata caacgcgcct
    19981 ttttggcggt tattgctatg agtcttttct caccggtatt gggaaccttc ctcatcttgc
    20041 gtcgtcagag tttgatgagt gataccctta gccacgtctc actttcaggt gtagcctttg
    20101 gtctggtttt ggggatttct ccaactattt ctactattgc cattgtcttg attgcggcgg
    20161 tctttctgga gtatctccgt acggtttaca agagctttat ggaaatcggg acagctatcc
    20221 tcatgtcaac aggtctggct gtttctctga ttgtcatgag caagggtaaa agctcgagtt
    20281 caatgagttt ggaccaatat ctctttggtt cgatcgtgac tatcagtgaa gaacaggtca
    20341 tttccctctt tgtcattgcg gcggttgttt tgattttgac ctttctcttt cttcgtccta
    20401 tgtatatctt aacttttgac gaagatacgg cctttgtgga tggcttgcca gttcgtacca
    20461 tgtccattct ttttaacatg gtgacagggg tggctattgc ccttatgatt cctgcagcag
    20521 gagctcttct ggtatcgacc attatggtct tgccagctag tattgccctg cgtctgggga
    20581 aaaactttaa atcggttatg ctgcttgcca gtgcgattgg ctttttggga atggtagcag
    20641 gactttacat ttcctactat gcagaaacac ctgcaagtgc aagtattacc attatttttg
    20701 taactgtctt tatactaatc agtttagtaa gacgttttat caaataggag acgaacgtga
    20761 aaaaaattag cttattacta gccagtctat gtgccttgtt tttagtggct tgttccaatc
    20821 aaaaacaggc agatggtaaa ctcaatatcg tgacaacctt ttaccctgtc tatgaattta
    20881 ccaagcaagt cgcaggagat acggctaatg tagaactcct aatcggtgct gggacagaac
    20941 ctcatgaata cgaaccatct gccaaggcag ttgccaaaat ccaagatgca gatacctttg
    21001 tttatgaaaa tgaaaacatg gaaacatggg tacctaaatt gctagatacc ttggataaga
    21061 aaaaagtgaa aaccataaag gcgacaggcg atatgttgct cttgccaggt ggcgaggaag
    21121 aagagggaga ccatgaccat ggagaagaag gtcatcacca tgagtttgac ccccatgttt
    21181 ggttatcacc agttcgtgcc attaaactag tagagcacat tcgtgacagc ttgtcagcag
    21241 attatcctga taaaaaagag acctttgaga agaatgcagc tgcctatatc gaaaaattgc
    21301 aagccttgga taaggcttac gcagaaggct tgtctcaagc aaaacaaaag agctttgtga
    21361 ctcaacacgc agcctttaac tatcttgcct tggactatgg actcaaacaa gtcgcaatct
    21421 caggactttc tccagatgca gagccatcag ctgctcgctt ggcagaattg acagagtatg
    21481 tcaagaaaaa taaaatcgcc tatatctatt ttgaagaaaa tgcctcacaa gcccttgcta
    21541 acacactttc aaaagaagca ggtgtcaaaa ctgatgtcct caatccttta gaaagtctga
    21601 cagaagagga cgccaaggct ggagaaaact acatttccgt gatggagaaa aacctcaagg
    21661 ctttgaaaca aacaacagac caagaaggcc cagcaatcga acctgaaaag gcagaggata
    21721 ccaagacagt ccaaaacggt tatttcgagg atgcagctgt caaggaccgc accttgagtg
    21781 actatgcagg taactggcaa tcagtttatc ctttccttga agacggcacg tttgaccaag
    21841 tctttgacta caaggctaag ttgactggta agatgaccca ggctgagtac aaggcttact
    21901 atacaaaagg ctatcagaca gatgtgacta agattaacat tactgataat actatggaat
    21961 ttgttcaagg tggacaaagc aagaaataca cttacaagta tgtcggtaag aaaattttga
    22021 cttacaagaa aggcaatcgt ggcgtgcgtt tcctctttga agccacagat gctgacgctg
    22081 gacagttcaa gtatgttcag tttagtgacc acaatattgc cccagttaag gcagaacatt
    22141 tccatatctt ctttggaggc acaagccaag aagctctatt tgaagaaatg gataattggc
    22201 caacctacta tccagataac ctatctggcc aagaaatcgc tcaagaaatg ttggcgcatt
    22261 gatgagaaat cgactagttc ataagagcta gtcggttttt tgatactaga tggctaactt
    22321 cattatagac ctttcagaac tttaaacaat aaataaaact cttgaaatat ctgggcttat
    22381 atgctagaat gtagttagtg tataaggttc attagaacac caaagcccct aactagtgcc
    22441 atagttaagg gcttttttga cgtatcttag cgatttaacg ggtgtttata ggctagtcag
    22501 tcggtctact tcttaccatc tagccatttg cagacgaaat acaagataat tccagctata
    22561 acatctgcta taatagtaag agcaagctct ggtataaggc tcattagttt cacctcctct
    22621 cacgaaccca taggaacgta atcggtaacc gatgacaaaa gtattatatc acactaaatt
    22681 tagatcatca acctcactta atgcttgaac tattgtagat tatatgctaa aatgtagtta
    22741 attgataagg ttcattagaa caccaaagcc cctaactatg gccgtagtta agggcttttt
    22801 tgacgtatct tagcgattta acgggtgttt ataggctagt cactcggtct acttcttact
    22861 atctagccat ctgcagacga aatacaagat aattccagct ataacatccg ctataatagt
    22921 aagagcgagc tctatgataa ggctcattag tttcacctcc tctcacgaac ccataggaac
    22981 gtaatcggta accgatgaca aaaatagtat accacaatac atttagatca tcaaggtcac
    23041 ttaattcttg aaatataggg tctaggcgac aaagtcttta aaatcagaaa aacgcataat
    23101 atcaggtgtg caaaaacttg atactatgcg ttttattgtg ggaaggttta ctccattttc
    23161 tcctgaaatt gagtttttgt ccagcctctg tttttagggt tgctgagaaa ataatgtcat
    23221 gtggtgaata tttgtaaatc agtcagcaga cagaacgaat actcttcgaa aatctcttca
    23281 catcatgtca gcttcgtctt tccgtatata tgtgactgac ttcatcagtt ctatctacaa
    23341 cctcaaaaca gtgtttcgag ctgacttcat cagttttcaa atctgtactt tgagcaagct
    23401 gagactagct tcctatttga ttttcattga atatcagaaa cccattctcc atcaaataat
    23461 tcgactgcgt ctaataattt ttggtctggc aaggtgtcag aaataaaggt tgtgtatttg
    23521 gagaggggat taattttaaa aaatccagtc ttgtaaaatt tagaactatc aatcagtaag
    23581 atggtttcat gggctttgtc aataatattc ttttttgaaa tagcttggct gagagaagct
    23641 tcataaacat attggtcatc aatacctctt gctgaacaaa atgctaaatc gatattaaaa
    23701 tgatctaata aagaattttc cttatcatag ttgaccacgg aacaggattg atgtttgacc
    23761 tcgccagatg tgataaagat tttggagcta tctttaacag tttcagatag ggtttgtgca
    23821 gtatgtaaac catttgtaaa aataatcaaa ttatcaagtt cagaaagata gggacagagt
    23881 tcgtagacag tagtactgga atccagatag atacacatac cagaccgaat aaagtcttta
    23941 gcgagactag cgattagtct tttttgccta gtactttctc cttcccgtat ttgatgagaa
    24001 agttcaattg tgttcataga ggacagggtc acgtatccgt gctttctttt gataagacct
    24061 tgattttcta agaaaattaa atcacgacgt aaggtacttg tgctggagaa agtgatttct
    24121 gccagctctt ttacggcaat tctttttttc tttttaataa tttcaatcaa ttcaagtaca
    24181 cgttcatctt ttatcataag ctcctcctaa tttatcattt caactatatt atagcacaaa
    24241 ttggaggaat ttgaattatt tttatgaata ttgggttaac atttgaacat tattcaagta
    24301 agcgttcaca tattgaaaaa ataaaacgtg gggattataa taaagttaat caaggacgaa
    24361 gagagaagaa aaatggaagc ggttttagca atagatttag gtgcgacttc tggaagagca
    24421 atcgttggtt acctttctga aaataaacta gtaatggaag aaataaatcg cttttctaat
    24481 ctacctatta gagtaaaagg gcatttatct tgggatattg actttctact agctaaaatt
    24541 cttgaaagta tccgcttggc taatactagt tacaagattt tatctatcgg tattgacaca
    24601 tggggagttg attttggact gattgataat gaaggtaagc tgttatcaca acctgttcat
    24661 tatcgtgatg aaagaacaaa gggagtgtta aaggaaatat ctgaaatgac tgaattagaa
    24721 aaactgtatt cagagacagg aaatcagatt atggagataa ataccttgtt tcaactcttt
    24781 aaggcacgtc aagaatctcc tgactctttc tataagacca ataagattct tttaatgcca
    24841 gatttgttta attatctctt gacaggtaag tttgctacag aaaaaagcat tgcttcaaca
    24901 actcaattat ttgatcctag gagtcaaaat tggaatcaga atatcttaaa actatttgaa
    24961 ttggattcat ctttacttcc tgaaattgtt tcagagggaa atgttcttgg aaggataaaa
    25021 gaggagtatg gtttatgcga tattcctgtt gtgaatgttt gtagtcatga tacagcaagc
    25081 gcgattgtct cagtacctaa gacagaaggt agtttattta tttcatcagg tacttggtct
    25141 ttggttggag tggaacttac ttcaccgatt cttactaccg aatccttcag ttatggattt
    25201 acaaatgaag tcggtaaaga tggagtgatt acatttctga agaattgtac agggttgtgg
    25261 atcatagagg aactaagacg ttcatttgaa cgaagaggga aagcctattc ttttgatgat
    25321 attaggacaa tggtggagaa agaaaaagaa aatcttcctc tgattgatac tgaatcaact
    25381 gaatttgcaa cagaatctga tatgcacaag actttgacag aatatctagc ttatcatcat
    25441 gaaactagag agtggacaga tggacaacta tttaagattg tttatgaaag cctagctgaa
    25501 acgtatagga aagcgataga gttactagaa gaactaactc ataaggttta taagaggata
    25561 tatgtgattg gaggaggtgc tagagccagt tactttaacc aaatgattgc tgatagaact
    25621 ggtaaagagg ttcttacagg ttcgactgag ggtacagctg tggggaatat tgttgtgcag
    25681 ctcatagcta tgggacaatt aaaagggatg gaagaggctc accatgttat tgaggagttt
    25741 ctacaattag agagttatta cttccaaaag aattaaaaag attgagagtt tgtaaatttg
    25801 cctccctccc ccttcttagc ttttgtgcag gaagggggga taattggtga attgaaaaat
    25861 atttagtgtt ttgatatgag gaggacaagg atgtcagatg taaaacaaga attaattaaa
    25921 tatggtaaga agctagtaga aacagatttg acgaaaggaa caggtgggaa tctcagcgtt
    25981 ttcgatcgtg aaaaacaatt gatggcaatt accccgtcgg gtattgattt ctttgaaatc
    26041 aaagaatccg atattgtagt gatggatatt aatggaaatg ttgtagaggg agaacgcttg
    26101 ccatctagcg aatggtatat gcatttgatt caatatcaaa ctcgtgatga tatcgatgca
    26161 attatccatg ctcatacaac ttatgcaaca gtattagctt gtctcagaga accacttcca
    26221 gcgagtcatt atatgattgc agtggcaggg aaagatgttc gggtagctga gtatgcaaca
    26281 tatggcacga aagaattggc tgtgaatgca gctaaagcaa tggaaggtcg tagagcagtt
    26341 ttactagcga atcatggaat tttagcaggt gcacaaaatt tattgaatgc atttaatatt
    26401 gttgaagaag ttgaatattg tgcaaaaatt tattgtttag ctaagaattt tggagagcca
    26461 gtagttcttc ctgatgagga gatggaattg atggcagaaa aatttaaaac atacggtcag
    26521 agaaaatagg gaggatatta atgttaaaac atataccgaa aaatatttct ccagatttat
    26581 tgaagacttt aatggaaatg ggacatggag atgaaatagt attagctgac gcgaattacc
    26641 cttccgtctc atgtgcgaat aaattaattc gttgtgatgg tgtaaatatt ccagaattat
    26701 tagattccat tctgtattta atgccattag atagttacgt cgatagttca attcagttta
    26761 tgaacgttgt ttcgggtgat gatattccta agatatgggg tacctataga cagatgattg
    26821 aaggtcatgg tacagatctt aaaacgatta cttatcttag aagagaagac ttttatgaac
    26881 gtagtaagaa agcttatgct attgttgcta caggagaaac ttcactttat gctaatatta
    26941 tccttaagaa aggagtagtt gttgaaagag aaaatgttta atagaggaat tttagttgcc
    27001 agtcatggta attttgctag cggagctctc atgaccgcag aaatgtttgt tggtgagaca
    27061 acaaatgata gagttaggac attaggtttg atgcctggag agaatattgt agagtttgag
    27121 cattatttta aaaatcaagt ggatgaactg ttagactcaa atcaagaggt tatcgttttg
    27181 actgacttga ttggaggaag tcctaataat gttgctttgt cacggttttt aaatttggat
    27241 tcagttgata ttgtaacagg gtttaatatc cctctcctag tggaattaat atcaaattat
    27301 gattcaaaaa tcaatttaga agaaattgtt cacaatgctc aaaatagttt gtttaatgtt
    27361 aaacaacaac ttaacgtaga ggaggaagaa gatttatgtc tatagagttt gttcgtattg
    27421 atgaccgtct ggtacatggt caagttgtca ctacgtggct aaaaaagtat gatattgagc
    27481 aagttatcat tgttaatgat cgcatctcag aagataaaac acgacaatct attttaaaga
    27541 tttctgcacc agtaggttta aaaattgttt tctttagtgt aaaacggttt gtggaagttt
    27601 taaactctgt gccaataaaa aagagaacaa tgctgatata tacaaatcca aaagatgtgt
    27661 atgattctat tgaaggaaat ttaaaattgg agtacctcaa tgtaggacag atgagtaaaa
    27721 cggaggaaaa tgaaaaggta acgggaggtg tagctctagg tgaagaagac aaatattatt
    27781 ttaagaaaat agttgataag ggaacgagag ttgaaattca aatggttcct aatgataaag
    27841 ttacaatgtt ggaaaaattt ttataaaaat aatttaagga ggtacagtat atgctattca
    27901 cacaagcatt actggtaaca ttagttggga ttattgccac tattgactat aatggaccgt
    27961 tatttatgat tcaccgtccg ttagttacaa gtgcaatggt tggcttagtc ttaggagatt
    28021 tcacccaagg tgttcttatt ggttcagctc ttgaattaac ttggctcggt gtaacaggta
    28081 ttggaggtta cactccacca gatactattt caggtgcgat tattggtact gcatttggta
    28141 ttttatctgg tcaaggagaa actgctggta tcgctatagc agttccaatt gcagttgcta
    28201 cccaacagtt ggatgttctt gcaaaaactt tagatgttta ttttgtgaaa aaagctgata
    28261 atgatgctaa aaacggagat tattcaaaga tcggttttta tcattattca agtttagttt
    28321 taatcacgtt atttaaaatt gtaccaattt tcctagctat tatgcttgga ggggaatatg
    28381 tggcagactt gtttgctaag gttccaccaa tcgttatgca gggacttaac tctgcaggtg
    28441 ctttactacc ttcaattggt tttggtatgc ttttaaatat gatgctcaag aaaaatatgt
    28501 gggtattctt gttgattgga ttcatttgtt ctgtgtatgg aggaatgtca accattggga
    28561 tctcactagt tggtattgcg gtagcatact tctacgatat gattggaagt aaaccacaag
    28621 aaacaacttc aagtagtgat gttgaggagg atcttgatct atgatgaata ataaagtaac
    28681 taaagttgaa cttaaaaaag ttttcaaacg aagttttatg tatggttctt catggaacta
    28741 tgagagaatg cagaacctag gttttctata tacaattctt ccagtattga aaaaactata
    28801 cccagacaaa gattcagctt ctcctgcaat gaaacgtcac cttgagtttt tcaatactca
    28861 tcaaacagcg gcaccattta ttcttggagt tacttccgct atggaagaac aagaaggaaa
    28921 tgaaggtgca gcttcaatta ctggtattaa agttggcttg atggggccac tggctggtct
    28981 aggagatagt ttgttctggc tgacactagt tcctatctgt tttagtattg gtgcgtctta
    29041 ttctaaagac ggcggtgctt taggtatctt tatcgcctta atattgttta atattattaa
    29101 tattcctgtt aaatatttcg gtttgaaata tgggtatact aagggttcta gtcttatcca
    29161 agaaaataat acaaaaggaa cattgaatcg cgttacgagt atggcgacag cattagggct
    29221 agtactagtg ggtggtttga ttccatcaat ggttggtatt aattttggat tagaatttaa
    29281 gcagggggaa cttgttattt ctgttcaaga aatgattaca aaattaattc caggatttat
    29341 ccctatggct ttgactttat taatgtgtaa attaattaga aaaggaaaga atccggttgt
    29401 actaatcttt agtgttatgg ctattggagt tatcctagtt gttttaggaa ttttgaagta
    29461 gtagaaagtg tggaggtggt atttgggata tcacctccat tttggaagag aggtaaagag
    29521 tgaaattatg gtataagaaa gctgcctcaa attggaatga agccttgccg attgggaacg
    29581 gtcatttagg tggtatgatt tatggttcag ctacaaaaga atgtattcaa ctaaacgatg
    29641 agactatttg gtatagagga aagtcagata gaaataatcc agactcacta ttgcatctta
    29701 aaaaaattcg ggaatatctt ttagatggag aaattcagaa agccgaagaa ttgataaagt
    29761 taacaatgtt tgctacccca agagatcaaa gccactatga attacttggg gaactttaca
    29821 ttgagcatat agatattcag tcttgtgctc tttcattgta tgaaagagag ctagatttag
    29881 atacagctat ttctaatgtt gtgtttgagc ctaatagttg taatttacaa ataaaaagag
    29941 aatattttac gagttttaat aagaatattt tatgttgccg tatagtgtca tcagttcaaa
    30001 acacattaaa tttaaacatt aatttgggta gaaataaacg gtttaatgac gaagtatcta
    30061 aactggattc aagtacaatt ttaatgtcgg cctctgctgg aggtagaaaa ggtgttcagt
    30121 ttaaagtagt atgtcattct aaggttacgg atggtgaagt aagtgtattg ggagagacaa
    30181 tagttattcg gaatgctaca gaggtatttc tttatctcaa atcaatgacg gattattggg
    30241 gaaatataga tatttcttct cttcagggag aatttagtag tattgattac tttacagaaa
    30301 aagatgaaca tgtaaaaaaa tatcaggagc aatttaatag agttgatttt aaactagact
    30361 atagtaaaga ttgtcttagc attccaacga atctacttct tgaaaacact aaaaagtata
    30421 gtaactactt gactaacttg ttatttcatt atggaagata tctgttaata tcgtctagtc
    30481 aaccgaatgg tttacctgcc aatcttcaag gaatatggtg tgatgaatta aatccaattt
    30541 ggggttctaa atatacgatt aatattaata ctcaaatgaa ttattggatg gtaggtccat
    30601 gtgatttacc agaagtagaa tatccattat ttgatatgct cgaaagaatg agagaaccgg
    30661 gaagactaac cgctaagaaa atgtatggag ctagaggttt tacagcacat cataatacgg
    30721 atggttttgg cgatacggct ccccaatctc atgccatggg ggctgcaatt tgggtattaa
    30781 ctattccatg gttatgtact catatttggg agcactattt atatttccaa gatgagcgta
    30841 ttcttacgga acattttgaa atgataaaag aagcatttct tttctttgaa gattatttat
    30901 ttgaggtgga tggctacttg atgacaggtc caagtgtctc accggaaaat aaatatcgct
    30961 taaaaaatgg tattgaagga aatgcttgtc tatcatctac aattgataat caaattctaa
    31021 gatatttttg tgattcatgc attggcattg caaaacaatt aggagacaat tcggatttta
    31081 ttagtcgtgt gaaggagtta aaaaagaaac tacctaaaac aaaaataggt agtaatgggc
    31141 aaatccaaga atggttagaa gattatgaag aagtagagcc tgggcataga cacatttcac
    31201 ctctatttgg gctttatcct tataatgaga ttgatattca taaaactccg gaattagcag
    31261 aagcagctaa aatcactatc aataggagat tatcaaacgc taacttttta tcttcacagg
    31321 agagggagca agcgattaat aattggttag taagtggttt gcatgctagt acacaaacag
    31381 gttggagtgc tgcatggctg attcattttt ttgcgagact atatcaaggt gaacctgctt
    31441 ataaccagat taatggtttg ttaaataatg cgactcttgg caatttattt cttgaccatc
    31501 caccatttca aattgatggt aatttaggtt tggtgagtgg aatttgtgaa ttattagtac
    31561 agagccatca taattggtta tcactaattc cagctttacc ttctgcttgg tcagaaggag
    31621 aagtgaaagg tttcagagta agaggaggat ataaggtatc gtttgcttgg aaaaatgggg
    31681 atataacatt cctaaaattg gaaggaggaa acaaagatca aaaagtaaga gtaagaatat
    31741 atggcaaaaa tactgatgta caaaatattg aattggtatt taattcagaa aaaattattg
    31801 agttaaattt ttaggtataa gtcatgaata aagaaaaaat aaaaagaaaa ttaatcacaa
    31861 tactgtttgt atgtattggg atgttatgtt ttggattgtt agcaggagtt aaggctgata
    31921 atcgtgttca aatgagaacg acgattaata atgaatcgcc attgttgctt tctccgttgt
    31981 atggcaatga taatggtaac ggattatggt gggggaacac attgaaggga gcatgggaag
    32041 ctattcctga agatgtaaaa ccatatgcag cgattgaact tcatcctgca aaagtttgta
    32101 aaccaacaag ttgtattcca cgagatacga aagaattgag agaatggtat gtcaagatgt
    32161 tggaggaagc tcaaagtcta aacattccag ttttcttggt tattatgtcg gctggggagc
    32221 gtaatacagt tcctccagag tggttagatg aacaattcca aaagtatagt gtgttaaaag
    32281 gtgttttaaa tattgagaat tattggattt acaataacca gttagctccg catagtgcta
    32341 aatatttgga agtttgtgcc aaatatggag cgcattttat ctggcatgat catgaaaaat
    32401 ggttctggga aactattatg aatgatccga cattctttga agcgagtcaa aaatatcata
    32461 aaaatttggt gttggcaact aaaaatacgc caataagaga tgatgcgggt acagattcta
    32521 tcgttagtgg attttggttg agtggcttat gtgataactg gggctcatca acagatacat
    32581 ggaaatggtg ggaaaaacat tatacaaaca catttgaaac tggaagagct agggatatga
    32641 gatcctatgc atcggaacca gaatcaatga ttgctatgga aatgatgaat gtatatactg
    32701 ggggaggcac agtttataat ttcgaatgtg ccgcgtatac atttatgaca aatgatgtac
    32761 caactccagc atttactaaa ggtattattc ctttctttag acatgctata caaaatccag
    32821 ctccaagtaa ggaagaagtt gtaaatagaa caaaagctgt attttggaat ggagaaggta
    32881 ggattagttc attaaacgga ttttatcaag gactttattc gaatgatgaa acaatgcctt
    32941 tatataataa tgggagatat catattcttc ctgtaataca tgagaaaatt gataaggaaa
    33001 agatttcatc tatattccct aatgcaaaaa ttttgactaa aaatagtgag gaattgtcta
    33061 gtaaagtcaa ctatttaaac tcgctttatc caaaacttta tgaaggagat gggtatgctc
    33121 agcgtgtagg taattcctgg tatatttata atagtaatgc taatatcaat aaaaatcagc
    33181 aagtaatgtt gcctatgtat actaataata caaagtcgtt atcgttagat ttgacgccac
    33241 atacttacgc tgttgttaaa gaaaatccaa ataatttaca tattttattg aataattaca
    33301 gaacagataa gacagctatg tgggcattat caggaaattt tgatgcatca aaaagttgga
    33361 agaaagaaga attagagtta gcgaactgga taagcaaaaa ttattccatc aatcctgtag
    33421 ataatgactt taggacaaca acacttacat taaaagggca tactggtcat aaacctcaga
    33481 taaatataag tggcgataaa aatcattata cttatacaga aaattgggat gagaataccc
    33541 atgtttatac cattacggtt aatcataatg gaatggtaga gatgtctata aatactgaag
    33601 ggacaggccc agtccctttc ccaacaccag ataaatttaa tgatggtaat ttgaatatag
    33661 catatgcaaa accaacaaca caaagttctg tagattacaa tggagactct aatagagctg
    33721 tggatggtaa cagaaatggt aattttaact ctggttcggt aacacacact agggcagata
    33781 atccctcttg gtgggaagtc gatttgaaaa aaatggataa agttgggctt gttaaaattt
    33841 ataatcgcac agatgctgag actcaacgtc tatctaattt tgatgtgatt ctatatgaca
    33901 ataatagaaa cgaagttgct aagaaacatg ttaataattt gtcgggtgaa tctgttagtc
    33961 tagatttcaa agaaaaagga gtaaggtata ttaaagttaa attactaacg agtggtgtac
    34021 ctttgagttt agcagaagta gaggttttta gagaatcaga tggtaagcaa tctgaagaag
    34081 atatagataa aataacagaa gataaagtag tttctacaaa taaggtagct actcaaagtt
    34141 caactaatta tgaaggtgtg gctgccttag cagttgatgg taataaagac ggagattatg
    34201 gacatcattc ggtgactcat actaaggcag attctaatgc ttggtggcag gtcgatctgg
    34261 gagaagagtt tacagtttct aaagttgata tttataatag aacagacgcc gaacctcagc
    34321 gtttatctaa ttttgatgtt atttttctat cttcatcagg agaagaagtt tttagaagac
    34381 attttgataa agtagttgat ggtctgttat ctttaaaagt accttctgta ggggctaagc
    34441 tagtcaaaat agaattaaaa tcatcagcta ttccgttaag tttagcggaa gttgaagtct
    34501 atggttcaaa gagaactccg aagaaacttt ccaatattgc gttagcaaaa gaaactagac
    34561 agagttcaac ggattacaat ggtttttctc gtctagcagt tgatggaaat aaaaacggag
    34621 attatggtca tcattcagtg actcatacca aagaagattc tccttcatgg tgggagatag
    34681 atttagcaca aaccgaagaa ttagaaaagt taattattta taatagaaca gatgctgaaa
    34741 ttcagagatt atcaaatttt gatattatta tatatgattc aaatgattat gaagttttta
    34801 cacaacatat tgacagttta gaaagcaata atctatccat agacttaaaa ggactgaagg
    34861 gaaaaaaggt tagaatttct ttgagaaacg caggaattcc tttaagttta gcagaggtag
    34921 aggtttatac ttataagtaa ttttaaaaat tatcacccag gctaccgtaa atataatgga
    34981 gatggtagta tgaaagaaac agaaaaataa gaggaaaata ttatgattca acatccacgt
    35041 attggtattc gtccgactat tgatggtcgt cgtcaaggtg tacgcgaatc acttgaagta
    35101 cagacaatga acatggctaa aagtgtggca gatttgattt ctagtacatt gaaatatcca
    35161 gatggggaac ctgtggaatg cgtgatttct ccatctacta ttggccgtgt accagaggct
    35221 gcagcttccc atgagttgtt taaaaaatca aatgtttgcg caacaattac agttacacca
    35281 tgctggtgtt atggtagtga aactatggat atgtctccag atattcctca tgctatttgg
    35341 ggatttaatg ggacagaacg cccaggagct gtctatcttg cagctgtact agcttcacat
    35401 gctcaaaaag ggattccagc ctttgggatt tatggaagag atgttcagga agctagtgac
    35461 acagctattc cagaagatgt caaagaaaaa cttttacgtt atgcgcgtgc agctcttgca
    35521 actggcttga tgagagacac tgcttaccta tcaatgggta gtgtttcgat ggggattggt
    35581 ggttctattg taaatccaga tttcttccaa gaatacttag gaatgcgaaa tgaatcggta
    35641 gatatgacgg agttcacgcg ccgtatggac cgtggtattt atgacccaga agagttcgaa
    35701 cgtgctatgg tttgggtaaa agaacatatc aaagaagggg ttgaccgaaa tcgtgaggat
    35761 ttgattcttt ctaaagaaga gaaagaaaaa caatgggaat ttgttattaa gatgttcatg
    35821 attggacgtg acttaatggt tggtaaccca agacttgctg aacttggttt tgaggaagaa
    35881 gcagttggtc accatgcttt agtagctggt ttccaaggtc aacgtcagtg gacagaccat
    35941 tttccaaatg gagattttat ggaaactttc ctcaatactc agtttgactg gaatggtatt
    36001 cgaaaaccat ttgtatttgc gacagagaat gattcactaa atggtgtgtc tatgctcttt
    36061 aattatctat taacaaatac tccacaaatc tttgctgatg tgcgtactta ttggagccca
    36121 gaggctgtta aacgtgtaac gggacatact ttagagggtc gtgctgcagc tggcttctta
    36181 catctaatca actctggttc ttgtacattg gatggtacag gtcaagctac tcgagatggc
    36241 aaacctgtta tgaaaccatt ctgggagttg gaagaaagtg aagtgcaggc tatgcttgaa
    36301 aatacagact tcccaccagc aaaccgcgaa tacttccgtg gaggaggatt ctcaactcgt
    36361 ttcttgacga agggggatat gccagtaaca atggtacgtc tcaatcttct aaaaggggtt
    36421 ggtccagtgc tacaaattgc agaaggttat acacttgaac ttcctgaaga tgttcaccat
    36481 actttagata atcgtacaga tccaggatgg ccaactactt ggtttgctcc acgtttgaca
    36541 ggaaaaggtg ctttcaagtc tgtctatgac gtcatgaata attggggagc taatcacgga
    36601 gccataacat atggacacat tggagcagac ttgattacct tggcttctat gttgagaatt
    36661 cctgtcaata tgcataatgt acctgaggaa gatatcttta gacctaaaaa ttggtcctta
    36721 tttggaacag aagatctaga atcagcagac tatcgtgcat gtcagttgtt gggaccactg
    36781 cataaataaa acttgtttat ataggaggtg aacttacgtc cctcctatcc ttttaaaaag
    36841 atttgttaaa caattcacaa ataattaaaa acgaatacaa aaagtaatat aatgatgtta
    36901 aatagatagc gcggaggcgc aggaggaaaa ttatatggct acattttatg ttccggcagt
    36961 caaccttatt ggaaaaggtg ttgtaaatga agtgggtcct tatatcaagg aacttggcta
    37021 taaaaaggca cttttggtga cagataagta catcgaaggc agtgacattt tacctaaggt
    37081 tttaaaacca ctggatacag aaggaatcga atatgtcatc tttagcgatg tagagccaaa
    37141 ccctacttgt aagaatgtca cagatggggt agctgctttg caagaacatg gatgtgattt
    37201 tatcatcagt cttggtgggg gttctccaca ggatgcagct agttgtattt ctatcatggc
    37261 tacaaatggt ggaaaaccac aggattatga agggcttcat aagtctgcta aaaaaggctt
    37321 gccagttgtg gctatcaata ctactgcagg tacatcagca gaaattacca ttaactatgt
    37381 gattactgat gaagaacgca aggttaagat ggtaatggtt gacaagaata gccttgctct
    37441 tatctctgtt aatgacccgg aactcatgct ttccaaacct aaaggcctga ctgctgctac
    37501 tggtatggat gctctgactc acgctgttga agctttggta acacctggtg cttatgatgt
    37561 aaccaagaaa ctgtctattg gtgctattga gcttatcaag gaatatcttc ctcgtgctgt
    37621 agaaaatgga catgatattg aagcgcgtga aggtatggtc aatgccatct tccttggtgg
    37681 tatgagcttt aataatgctg gtcttggtta tgttcactca atggctcacc aactcggtgc
    37741 agtatataat ttgccacatg gtgtttgctg tgccatgttg ctaccagtta tagaacgtga
    37801 aaatgctaaa cgtgtaccag aagctttccg caatgttgcc aaagccttgg gacttcatgt
    37861 agaaggtaaa tcagatcaag aatgtgccga ttatgcgatt gctgagattg agaagctttc
    37921 tgagacagta ggtattccta agaagctgac tgaacttggt attgaagaaa aagatttcga
    37981 ctttgaatac ctttctaaga atgccttgat tgatgcctgc gcaccaggaa atccatttat
    38041 gccaacctta gaagaaacga ttgcctttta taaagagtta ttttagcaag agattggacg
    38101 acaataggac aattcacctc taattattga catttcagga aaaatcgcag taaaaacggc
    38161 acagccttct ttaaatgtgc tataatacta gaaaaatact tgtggaggtt ccattatggc
    38221 aatatttttc atgatttttc tgattgtttg tgtgctccta ttggtgatag tcacactgag
    38281 tacagtttat gtggttcgtc agcagtcggt ggcgattatt gaacgctttg ggaaatacca
    38341 aaaggttgcc aatagcggta ttcatattcg cttgcctttt gggattgact cgattgcagc
    38401 acggattcag ttgcgcttgt tgcaaagtga tattgtggtt gagactaaga ccaaggacaa
    38461 tgtgttcgtt atgatgaatg tagcgactca gtaccgtgtc aacgagcaga gcgtgacaga
    38521 tgcttactat aaactcatac gtccagaatc tcagattaaa tcttatatcg aagatgctct
    38581 tcgctcttct gttccaaaat taaccttgga tgaattgttt gagaaaaaag atgagattgc
    38641 ccttgaagtt caacaccaag tagcagaaga aatgaccact tacggctaca ttatcgtgaa
    38701 aaccttgatt accaaggtcg aaccagatgc agaagttaag caatccatga atgaaatcaa
    38761 tgcggcgcaa cgtaagcggg ttgcagcaca agaattggcg gaagctgaca agattaaaat
    38821 tgtcactgca gctgaagccg aagcagaaaa agaccgcctt catggtgtgg ggattgccca
    38881 acaacgtaag gcgattgtgg atggattggc agagtctatc accgaactca aggaagccaa
    38941 tgttggcatg acagaagaac aaatcatgtc tatcctcttg accaaccagt atttggatac
    39001 cttgaatacc tttgcctcta aaggaaatca aaccatcttt ttaccaaata ctccaaatgg
    39061 tgtggatgat atccgaacac aaatcttgtc agcccttcgc gctgagaaga aataatagac
    39121 taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ctttgccgta tagatgttac
    39181 tgacttcgtc agttctatct gcaacctcaa aacagtgttt tgagctgact tcgtcagttc
    39241 tatccacaac ctcaaaacag tgttttgagc tgacttcgtc agtcttatct actacctcaa
    39301 aacggtgttt tgagcaacct gtggctagtt tcctagtttg ctatttgatt ttcattgagt
    39361 acaaagagct tggcaacagg ctctttttgt attgcgttta ttaagaaaaa caaaaaacat
    39421 cgatatacat ttaactaaaa attattgtat gttatctccc ttaattagga atgataaggg
    39481 aataactaga aagatttgtg aatacaaact atttctgata tacaaaatat acagtaataa
    39541 tgaatgatgg gagatgggat gaaagaattt caatttgaga gaaagcagcg tttttctttg
    39601 aggaaatatg caataggagc ttgttcggtc ttgctaggaa cgagtttatt tttttgctgg
    39661 tatgggtgct cagcctgtac aggatacaga aacgagttca gcactaattt caagtcatta
    39721 tttggatgag caggatttat ctgaaaagct gaaatctgag ttgcaatggt ttgaattaga
    39781 aaacaagctt ttgaacttat gggagcatta ggttactatg aaggatttgt tccttatgtt
    39841 tcaaatcaat acaaaaacca agctgaagaa gaaggcaaac cgctatctga taaatatatt
    39901 ttcgaaaaaa tcttaggaaa aacatatgca gccttcaaaa aagatcaaat taatgagcgt
    39961 gtcgagaaat taggtaagtt aaaacctatt acaataaatt acaacggaaa atcagaagta
    40021 attgatagta aagaaaaatt acaagagctt atgaataaag ccgttaaaga cgaagtggct
    40081 caaatatagt aaaatgaaat aagaacagga caaatcaatc aggacagtca aattgatttc
    40141 taaaaatgtt ttagaagtag aggtgtacta ttctagtttc aacatactat aaaatcaggc
    40201 aatacaacgg ctaaaaagtt tgagtttatc gaaataccag tgcaaaaact gaaaaaagcg
    40261 atttataaag ctcatctcaa agattcagat gactttagac cagaaacatc cacaccaaat
    40321 ctttttgaaa gctgtttgaa gctttgtcct tgctttctta gttcatagat ctgaacttta
    40381 tcttcataac tcaatttcat aataaaacac cccaaaagtt agatttattc tgtctaactt
    40441 ttggggtgca gttcattaat cggtcgattt ttttgtagaa acagttgcct gattaagttg
    40501 caagtcgata gacggcttcg gcataaatat ccatagcacg gtacaaatct tctagaacgg
    40561 cacattcatt tgcctgatgt tctgtctgct tcgctcctgg gaataaggcg ccgaaggcta
    40621 cacaatttgg catggtgcga gcaaaagtgg caccaccgga tgaaatagca ggactgttat
    40681 cgccagtctt ttcttggtag atttgcatca gtgtgctaac gagtttactg tcttttgcga
    40741 cgtatagagg cgctagatag tcaaactctt cgtagcggag ttggtagttt tgtgcacatc
    40801 ttgtaagcaa ctctactagt tcttccttgt cagctaagac aggagtccga atgtcaatac
    40861 ggatttcaga acgttcatga ttgatcatga gacctgcgac attaaaggat aggtgaccag
    40921 aaggttcatc tgctatatca ccaaagattt gtcttcctgt gccgtcttga cctgcttgtg
    40981 ttgcaagaaa actgagagca gggtgttctt ggagaggagc aagaatggta gctagtcgga
    41041 tgacagcatt gataccttga ctagcatcct tagcatgctt tggcactccg agaaccgtta
    41101 cggtttgttc agtggtttgg taatcataac cagcttcttt gagaccgtta caaacctgtt
    41161 catagaggag accttggtag ttggccttgt ctggtacaac gttaaaggcg cctcctactt
    41221 caagctctag ttgatccgat cccgggccat gaagtttgac ctgtagaagc cctttttcag
    41281 cataggtcag aggaaaagat gagtcaggtg caaagcccat actggcctgt tcttcgatgg
    41341 tattgtagcg tgccatgcag cgccagaggg tttcctcatc ggtaccaaag ataaagcgta
    41401 cgcgcttttt gaactgaata ccttggtcca gcaagctttt tactgcatag agagctgcga
    41461 gcgaagggcc tttatcatct tggacaccac gtccgaatac ccagccgtct ttgatagttg
    41521 cttcaaatgg cggtgtctgc caatctgctt catcacctga tggaacaaca tccaaatgac
    41581 agagaatggc cagaagctct gctccctgac cgatttctgc atatccgtaa taacctttag
    41641 ggtcaagata ggtagtgaaa cctatgtctc gacaaatctc taaagttttt tctaggacat
    41701 cttggattgc ttgtccaaaa ggtgttccat tttctccttc attgagtact gaaggatagg
    41761 aaatcaaggt ttttaatgat ataagaaatt catctttaac ttgatttgtt atatctattt
    41821 tcatggaatc acctcactca ctattttata ggaatggaag gaaggttcca aggagaagaa
    41881 gggcgatggt cactacaata atagcgacta cgagtttgcc catgaatttc caccaagtac
    41941 caatgttgat acgtccaagt gcaagagctc ccatcacaat accagatgtt ggtgcaatca
    42001 agttcaagac acctgaagca gattggtaag cagtgataat caagctagga cggacattta
    42061 caaattctcc aagtggagcc atgataccca tagttgcgct ggcaagacca gatgaagatg
    42121 ggatcaagaa tgacataggt agatagaaga tataagttac aacgataaag acttgtgaag
    42181 atagaccgct caagccttct ttaccccagt tgaggattgt atcggtaatc ataccgtcgt
    42241 tcatgataac ttgaatacca cgagcaatcg ctacgatcaa ggcaacactg agcaagtcag
    42301 cagcaccatt catgaaggaa gagataatct tatcttcttt aagaccataa ataacaccaa
    42361 tcaggatacc cataaaggca aagagcatgg cgccttctgg gaagtaccaa gtacctagtg
    42421 cagaagtaga tgaaccgaca atattaccaa taactggaag accagtcaac caagcattaa
    42481 agtcatcaaa aatggtaacg ccaaggtctg tccatggaat gaagctcaat accatcaaga
    42541 tgaatgtcaa cacaaataag aagagaactg atttttgttt gctgctaagt gtagattcta
    42601 cagatgaaga ttcttctacg ttaaagtgtt tcaaatcttc tttgcgagta ctataaacca
    42661 gtgacttagt cggatctttt tgaatcttat ccgcataacg gtaaacaaac caagtactaa
    42721 gagcagtcaa ggtaacccag aaaatcagac gaagtacgat accgtcccct gtaccaactc
    42781 ccgcagtcgc tgaagcaata cctgtcgcaa atggattcag agtagatgcc aaacagccga
    42841 tttgagaacc gagcaaaata attgcaacac cagtcaggct atcaaaacca acggccatca
    42901 taactggcac aaggagtgga tagaaggcca ttgtttcttc ccccatacca taagttgtac
    42961 caccgagggc aaacaaaggc atcagtacca aaattaacat tttttcgcgg cccttatact
    43021 tcttcacgat agaggcaatc cctacgtcaa gagcaccagt tttgttgaca atgccaagga
    43081 aaccaccaac cataaggatg aagaaggcta catcaatcgc tgcgctcgtt tctttaatga
    43141 gcgaaccttc ctctggatga gtacctagca tagcccgaat cggtgccatg aggacatccc
    43201 aaatcccttg tggattttga ggctgagcct cgtaaatacc ttctataaag gcccccgcag
    43261 ggataaacca agttagcact gccataatag caatgattat caataatacg gtgtaagatg
    43321 aaggcatctt aaaccctttt ttagcttttt cactcatttg tttttcctcc tgatgtctaa
    43381 caaagtgtaa aaaaccaact actttcttaa ataaacattc aagaaaacgc tttctattta
    43441 tatttgtttt accatattaa agtctaaaaa actaatatct tttgaaatat tgtacatgtt
    43501 ttcaagaata atttctaatt tgatataaag atactagaaa tagaatacat cttattagta
    43561 aaacaactta tcctttttca ataattgttc cgctttcaga ttcaatcaag gcgcctagat
    43621 tttcaaggga agtaataact gcttttcctt ctggacgacc attgacaaaa gcgatagctg
    43681 cttctacttt tggaagcatg ctacctggtg caaactgatc ttgtttgata tattcttcca
    43741 gctgggcaac attcacatgt tccaattttt cctggtttgg cttgttgtag ttaacaaata
    43801 cataatctac acctgtcaaa atgatgaaga ggtctgcatc aaccaattct gccaaacgtt
    43861 gggaagcgaa gtctttatca ataaccgctt cgacaccagt caaatgtcca ttgttttctt
    43921 tgacgacggg aataccgcca ccacctgcag ctacgacgac ttgaccatta tttaaaagag
    43981 tacggatggt ttcaatttct ttgatgtcaa caggttttgg tgaggcaacg accttacgcc
    44041 agccacggcc agcatcttcc ttgaaagtcg ctccgctttt ttcggcttct gcttttgctt
    44101 cttcttctga atagaaagga ccgattggtt tactcaagtt aacaaaagct ggatcatttt
    44161 tatctacgac aacttgcgtt acaacagagg caacattttt ttcgatgcct tcatccaaga
    44221 gagcattttg caaagcattt ttcaaccaga aaccgatgct accttctgtc atagcgacaa
    44281 gtgagtcgag tgggaaggca gggttctttt cagagtctga tgccaaatgt tggagcaaga
    44341 gattcccaac ttgaggtcca ttaccgtgag tgataatcaa atcatctcca tttttaatca
    44401 attttacaag atgcttagct gtttcaacta aagcttcttg ttgagccttt gctgatgggt
    44461 cagaagaaag aatcgcattt cctcccaaag ctactacaat tttacgattt gccataaatt
    44521 ctcctttatc acactcaata gaatgcgttt agatttcaat ttaatgattt ttcacatatt
    44581 ttataagaaa taatagatta ccattacata aaagaggacc ggactaaagc tattagtcgc
    44641 agccctcata gctgttggta gacggtttat tatctaaaat tatactttag gaatataaag
    44701 gttaccaagt gtcgcagcca taacagcttt gatagtgtgc atacggtttt ctgcttgatc
    44761 gaagtggcga gcgtacttgc tgcggaagac ttcgtctgtt acttccattt cttctacacc
    44821 aaatttttca gcaacgtctt taccataaac agtgtgagta tcgtggaatg ctggcaagca
    44881 gtgtaggaag atcaagtttt cattgcctgc ttttttaact aagtccatat tgacttggta
    44941 aggtttaaga agagctacac gttctgcgaa tttgtcttct tcacccattg atacccaaac
    45001 gtctgtgtaa agaacgtctg catctttaac tgcttcatca gcatcttcag tgatgagaac
    45061 atgtgcgcca ctttctttag caaatccttc tgccaattca acgatttctt tttctgggaa
    45121 gagttctttt ggtgagaaga tgtgaacatt gacaccaagg atagcacctg ttacgagcaa
    45181 gctgttggca acgttgttac gtccatcacc acagtatacc aatgtcaagc cttccaagcg
    45241 accgaagttt tcttgaacag tcaagtagtc agcgagcatt tgagttgggt gccattcgtc
    45301 agttagaccg ttccatactg gaacgcctga gaattctgcc aattcttcaa ccatacgttg
    45361 gctgaatccg cggaattcaa tcccgtcaaa catacgtccc aatactttag cagtatcttc
    45421 agtagattct tttttaccca actgaatatc atttgctccg aggtattctg ggtgagcacc
    45481 aaggtcgata gccgcagttg taaaggctgc acgagtacga gtagatgttt tttcaaatag
    45541 gagagcgata ttcttgccag caaggtagtg gtgttgaata ttgcgttttt tcaaatcttt
    45601 caagtgagct gaaagaccaa taaggtattc taactctgca cgggtaaagt ctttttctgc
    45661 taagaagctg cgtccttgga atactgaatt tgtcatttta ttatttcctc tttctatttt
    45721 ttacattttc tattgacgaa tgccaaacag cgattacact tcttcacgtt caaatggcat
    45781 agacatacaa cgaggtccac cacggccccg aaccaattca cttccgcgaa tcttaatcaa
    45841 gcgaagcccg tattcttcca aaatcttatt ggtcacggta ttgcggtcat aaacaactac
    45901 cacaccaggt gcgatggtca aagtgttaga accgtcgttc cattgttcac gcgcagctgc
    45961 tacgatattg ccaccaccgc aacgaatcaa atgaactttt tctacaccaa ggttttgagc
    46021 aagaagttca gctaagtcac ctttctcttc aacgatttta agtttttcgt tttcgtaagt
    46081 aactgagtaa acgtgaaggt cgccttcgat ttctgggtga atagtgaact tgtcatagtc
    46141 taccatagtg aagacagtat ccaagtgcat gaatttacgg ttgttagcaa attcaaaggc
    46201 caaaactttc ttgaagccaa catttttctt gaagatgttg accaaaagtt tttcgataga
    46261 agctgcgtct gtacgttgag agatacctac tgcaaggacg tctttagaaa gaactagctc
    46321 gtctccacct tcgatacgcg tatcttcttc acggttgtag accaaatcca cttttccgcc
    46381 atagattggg tggtatttga agatatactt accgtagagt gtttcacggt tacgagtgtc
    46441 tgcaaacatg tggttaagcg atacggcgtt tccaattgtt gcaaatgggt cgcgagtgaa
    46501 atagaggttt ggcatcgggt caattgcaaa tggataatct gattcaacta agtcagttag
    46561 atctttagct tcgtcaggaa tttctggcaa ttcaactttt tgaatcccag ccattgtttt
    46621 ttcaaccaat tcttggttgt ccttgatgcc gtgaagcaat tcacgaatag caaccttggt
    46681 ttgacgatca cggatgttgg cttcgtctaa gtattcctcg ataaattgat cgcggatttc
    46741 tggagaggtc aatgattcag cagcgagttg ttctaggtag agaacctcaa ttccttcatc
    46801 gcgaagagct tgggcaaatg catcatgttc tttttgagca tcttccaaga aaggaatatc
    46861 atcaaaaaga agcctttcaa gatagtccgg caacaagttt tctaactcct tgcctggacg
    46921 gtgcaacata acttttttca gtttcccaat ttctgagaag acctgaattg gatgagaaga
    46981 catgtatttt cctccttaaa aattttgact tggcaccatt ttgggtaccg cttacatgta
    47041 tgttataacg caattcctag gtaatgtcaa tggctataat ttctcggaaa ataatataaa
    47101 ttatgatgtt tagcacaatt ttatgttatt
//
LOCUS       DAVKAU010000013        45826 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVKAU010000013 DAVKAU010000000
VERSION     DAVKAU010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45826
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.013"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(76..1242)
                     /gene="recA"
                     /locus_tag="VWX48_000822"
     CDS             complement(76..1242)
                     /gene="recA"
                     /locus_tag="VWX48_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU9171474.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1297..2553)
                     /locus_tag="VWX48_000823"
     CDS             complement(1297..2553)
                     /locus_tag="VWX48_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU9171475.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKVSSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2637..3653)
                     /locus_tag="VWX48_000824"
     CDS             complement(2637..3653)
                     /locus_tag="VWX48_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU9171476.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3661..4179)
                     /locus_tag="VWX48_000825"
     CDS             complement(3661..4179)
                     /locus_tag="VWX48_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171477.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4169..4612)
                     /gene="tsaE"
                     /locus_tag="VWX48_000826"
     CDS             complement(4169..4612)
                     /gene="tsaE"
                     /locus_tag="VWX48_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU9171478.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4698..5318)
                     /locus_tag="VWX48_000827"
     CDS             complement(4698..5318)
                     /locus_tag="VWX48_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171479.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5701..6564)
                     /locus_tag="VWX48_000828"
     CDS             complement(5701..6564)
                     /locus_tag="VWX48_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9171480.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFAYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            6753..6923
                     /locus_tag="VWX48_000829"
     CDS             6753..6923
                     /locus_tag="VWX48_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171481.1"
                     /translation="MKKNRGIQKLAILVLLDVFMFSNTIPYQQFIQKNRQLEIRVQSQ
                     KKSNGLDVGKAD"
     gene            7373..9388
                     /locus_tag="VWX48_000830"
     CDS             7373..9388
                     /locus_tag="VWX48_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9171482.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            9390..10022
                     /locus_tag="VWX48_000831"
     CDS             9390..10022
                     /locus_tag="VWX48_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171483.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSDSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVTLAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(10950..11363)
                     /gene="ndk"
                     /locus_tag="VWX48_000832"
     CDS             complement(10950..11363)
                     /gene="ndk"
                     /locus_tag="VWX48_000832"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU9171484.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(11474..15151)
                     /gene="rpoC"
                     /locus_tag="VWX48_000833"
     CDS             complement(11474..15151)
                     /gene="rpoC"
                     /locus_tag="VWX48_000833"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU9171485.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15184..18795)
                     /gene="rpoB"
                     /locus_tag="VWX48_000834"
     CDS             complement(15184..18795)
                     /gene="rpoB"
                     /locus_tag="VWX48_000834"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9171486.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19211..19281
                     /locus_tag="VWX48_000835"
     tRNA            19211..19281
                     /locus_tag="VWX48_000835"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19243..19245,aa:Cys,seq:gca)
     gene            complement(19479..20810)
                     /locus_tag="VWX48_000836"
     CDS             complement(19479..20810)
                     /locus_tag="VWX48_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU9171487.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21101..21925)
                     /gene="endA"
                     /locus_tag="VWX48_000837"
     CDS             complement(21101..21925)
                     /gene="endA"
                     /locus_tag="VWX48_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU9171488.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     GPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(21964..22152)
                     /locus_tag="VWX48_000838"
     CDS             complement(21964..22152)
                     /locus_tag="VWX48_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9171489.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22145..23428)
                     /gene="murA"
                     /locus_tag="VWX48_000839"
     CDS             complement(22145..23428)
                     /gene="murA"
                     /locus_tag="VWX48_000839"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9171490.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23452..23682)
                     /locus_tag="VWX48_000840"
     CDS             complement(23452..23682)
                     /locus_tag="VWX48_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU9171491.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(23740..24777)
                     /locus_tag="VWX48_000841"
     CDS             complement(23740..24777)
                     /locus_tag="VWX48_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU9171492.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     LYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(24761..25249)
                     /gene="coaD"
                     /locus_tag="VWX48_000842"
     CDS             complement(24761..25249)
                     /gene="coaD"
                     /locus_tag="VWX48_000842"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU9171493.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25239..25778)
                     /gene="rsmD"
                     /locus_tag="VWX48_000843"
     CDS             complement(25239..25778)
                     /gene="rsmD"
                     /locus_tag="VWX48_000843"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU9171494.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(25843..26835)
                     /locus_tag="VWX48_000844"
     CDS             complement(25843..26835)
                     /locus_tag="VWX48_000844"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU9171495.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(26947..27630)
                     /locus_tag="VWX48_000845"
     CDS             complement(26947..27630)
                     /locus_tag="VWX48_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU9171496.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLGFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(27686..28426)
                     /locus_tag="VWX48_000846"
     CDS             complement(27686..28426)
                     /locus_tag="VWX48_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU9171497.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28460..28738
                     /locus_tag="VWX48_000847"
     CDS             28460..28738
                     /locus_tag="VWX48_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU9171498.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            28816..29742
                     /gene="yidC"
                     /locus_tag="VWX48_000848"
     CDS             28816..29742
                     /gene="yidC"
                     /locus_tag="VWX48_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9171499.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(29817..30611)
                     /gene="pflA"
                     /locus_tag="VWX48_000849"
     CDS             complement(29817..30611)
                     /gene="pflA"
                     /locus_tag="VWX48_000849"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU9171500.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(30737..31987)
                     /locus_tag="VWX48_000850"
     CDS             complement(30737..31987)
                     /locus_tag="VWX48_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU9171501.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLIRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32054..32881)
                     /gene="purR"
                     /locus_tag="VWX48_000851"
     CDS             complement(32054..32881)
                     /gene="purR"
                     /locus_tag="VWX48_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU9171502.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33148..34089)
                     /locus_tag="VWX48_000852"
     CDS             complement(33148..34089)
                     /locus_tag="VWX48_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU9171503.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34079..35335)
                     /locus_tag="VWX48_000853"
     CDS             complement(34079..35335)
                     /locus_tag="VWX48_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU9171504.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35337..35999)
                     /locus_tag="VWX48_000854"
     CDS             complement(35337..35999)
                     /locus_tag="VWX48_000854"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU9171505.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(35962..36618)
                     /locus_tag="VWX48_000855"
     CDS             complement(35962..36618)
                     /locus_tag="VWX48_000855"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU9171506.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(36629..37507)
                     /gene="rsgA"
                     /locus_tag="VWX48_000856"
     CDS             complement(36629..37507)
                     /gene="rsgA"
                     /locus_tag="VWX48_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU9171507.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(37509..38381)
                     /gene="rsmA"
                     /locus_tag="VWX48_000857"
     CDS             complement(37509..38381)
                     /gene="rsmA"
                     /locus_tag="VWX48_000857"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU9171508.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFIHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(38512..38820)
                     /locus_tag="VWX48_000858"
     CDS             complement(38512..38820)
                     /locus_tag="VWX48_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171509.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(38813..39454)
                     /locus_tag="VWX48_000859"
     CDS             complement(38813..39454)
                     /locus_tag="VWX48_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171510.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVSLAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(39456..41486)
                     /locus_tag="VWX48_000860"
     CDS             complement(39456..41486)
                     /locus_tag="VWX48_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9171511.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQGLFTDYL
                     QNFSSESVEVTSQKYYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(41755..42654)
                     /locus_tag="VWX48_000861"
     CDS             complement(41755..42654)
                     /locus_tag="VWX48_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9171512.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIAHRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQGYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(42726..43286)
                     /gene="rnmV"
                     /locus_tag="VWX48_000862"
     CDS             complement(42726..43286)
                     /gene="rnmV"
                     /locus_tag="VWX48_000862"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU9171513.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLVGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(43286..44059)
                     /locus_tag="VWX48_000863"
     CDS             complement(43286..44059)
                     /locus_tag="VWX48_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU9171514.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(44364..45263)
                     /locus_tag="VWX48_000864"
     CDS             complement(44364..45263)
                     /locus_tag="VWX48_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU9171515.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKEKV
                     KVAILQANGSALDGATINVAGYGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATP
                     EYKLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESA
                     KNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETI
                     GVQAIVMVTVPKRPVAPNTAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAAL
                     ASLGLVVATSGFALLGRKTRRRK"
     gene            complement(45547..45681)
                     /gene="rpmH"
                     /locus_tag="VWX48_000865"
     CDS             complement(45547..45681)
                     /gene="rpmH"
                     /locus_tag="VWX48_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU9171516.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        13095 a        10388 c         8659 g        13684 t
ORIGIN      
        1 caagctacta tatataatct aaaaacttga atcaaaaatc gaaaaagtag cggatttctc
       61 cactgcttta acagcttatt cttcaatttc gatttcaagt tcatcgccta agtcaagcgg
      121 aacttcttca ttcactgctt cttctttctt tggctcatct tttttgtttt cagtatcttg
      181 ttctgaaact tcttctccat caatcaagcc aaatttagaa cggacttgct tatcaatttc
      241 atcaaagatt tctgggtgct ctgccaagta tttcttagca ttctcagaac cttgcccaat
      301 tttttcatct ttgtaagaat accaagcccc tgcttttttg ataatatcca aatcgcttgc
      361 aatcttcaaa agctcaccag tcttagaaat tccttctccg tacataattt caactacggc
      421 ttccttaaac ggtggagcta ccttattttt tacaacctta atcttagttt ctttaccgac
      481 attggtttct ttttggtcac cagttccctt aatttgtgta ttaccacgaa catccaagcg
      541 gactgaagca tagaatttca aagcacgtcc gcccggtgtt gtttctggat ttccaaacat
      601 cactccaact ttttcacgca attggttgat aaaaatggca attgttttgg ttttattgat
      661 agaggcgcca agtttacgca tggcctggct catcatacga gcctgcaaac caacatggct
      721 atctccgata tctccatcaa tttccgcacg aggaacaagg gcagcaactg agtcgactac
      781 gacaagatca actgcacctg agtcaatcaa ttttcccgca atctcaagac cttgctctcc
      841 tgagtctggt tgagacaaga gcaattcgtc aatattgaca ccaagggccg cagcataagc
      901 tggatcaagg gcatgttccg catcgataaa ggcagcaatc ccaccttctt tttgcgcttg
      961 tgcaactgca tgaagggcaa ccgttgtctt accagatgac tctgggccat agatttcgat
     1021 gatacgtccc ttaggataac cacctgagcc aagggcaatg tcaagagcta aagaacctga
     1081 gctcatcact tgcacctttt gctccgcacg ttcacccaaa cgcatgattg atcctttacc
     1141 aaagtctttc tcaatcaatt taagagcgtc attcaaggcc ttttcacgtt ctgccccaaa
     1201 tttttttgaa atttcttcta atttttttgg ttttttcgcc attctattct cctacattct
     1261 aatgatcctc agacctatct actattatat caaaagttag tcacttaata aagccttgcg
     1321 aactaggtta aaggcatgca taaccgcaat gtgacgtaca tctgctcggc ttctgcctcc
     1381 aatattaacc ttgataacct cagttccttg atcttgcgcc aagcctatga agactgtccc
     1441 aactgggtgt ccttctaggc tatctggtcc tgccactcca gtcaaactaa ttccaaaatc
     1501 agactgggtc ttgcttcgtg cctgctcagc catcttctga gctgtaaatt cagacaccac
     1561 accatgttct tccaaattct tggcaggaat atccaacatc cttgattttt cctccaagct
     1621 ataggtcaca aaaccaccct taaatatact tgaaactcca gaaaaattcg ccacggtagc
     1681 ttggaaaaga cctgccgtca aactctctgc agccgcgatg gttttccctt gccttttcag
     1741 ttcttctacc acaatgctgg ctaaactagt ttcttcccca taaccatagc aaaagtctcg
     1801 taaagaaatt ccttcgaaag tctggcagtc caagatttga ttttccaaga tatccagcgc
     1861 ttgattcgcc tcttcttgac tgctaacctt tgttgacaga cgtagagtga cttctcctgt
     1921 cttggcataa ggggccaagg taggatcgat ctgattatca attaaatcag ccaaaatcgt
     1981 aaccaactgg ctctcgccaa tcccaaagaa acgaagaact cgggaataca gcttgctccc
     2041 tgtcatcaac ttgggtagaa gttggtttaa gaccatgggt ttcaattcac ttggcggacc
     2101 tggaaggacg acataggtca ctccgtctac ttctaatttt cctccaacag ccagtcctgt
     2161 ttcgtttggc agtggaatcg ctccttctac aatttgagct tgtctttcgt tattcggtgt
     2221 tcgggcatag tctggtcgca gggcaaaaaa gatatccaac ttctcctgag cctgaggatc
     2281 aaagactaat gctttcccta aaaatttagc tagggtttgt ttggttaggt cgtcctcagt
     2341 tggccccaaa ccgcctgtca aaatcaccag actgctacgt tgactggcaa tctcaagcaa
     2401 agacaagaga cgaacttcat tgtctcctac agccgtctga aaatatacat ctaccccaat
     2461 ctcagctagt ttttccgaca aaaactgggc attggtgttg acaatctgtc ctgtcaaaat
     2521 ctctgttcca acagcaatga tttctgcttt catgtttcct cctacctatc tattcgtatt
     2581 tttttgaaaa aatcgcagga attttcctac gattgatttt ttatttgtat caaaagttaa
     2641 ttatcttcat caccaacagg tgctctgcca aataaatctt caaataaaac cgcattggtt
     2701 tcaagctgag taacttcttc ttgtcccaaa gaacgtcgga gtatattttg catttccaac
     2761 atatgtgctc tcgaaacaat ctggtaagaa acaccttgaa gtatctctcc ttcaccctgc
     2821 aactgctgag tttcaatggt tttaaatgaa tctttatagc ctagcaagtt agggatactt
     2881 tttgcagaca aatcaatatt ggtctgcata ttgtcactca aagcttttag aatctcttga
     2941 taatgaccaa tgctatttaa actgagagct ttttccatga ctttttgaat aacttcacgt
     3001 tgacgttttt gacgaccata atccccctca ggatcttggt aacgcattcg tgcatagact
     3061 agggcttctt ctcccccaat atgttgctcc ccaacaccga tagaaatagt attaaattct
     3121 tcttggtcac tgatagaaat tgggaaacct aggatattat tgactgtaat acctcctact
     3181 gcatccacta gtttttgcaa ccctctcata ttgaccatca catagcgatc aatatggata
     3241 ttcatcattt tttgaatggt ttctatagca agctctgctc caccatctgc atatgctgag
     3301 ttcagtttcg cttcatgagc ctgaccattc cctgattcaa tgcgcgtcag aatatcccgc
     3361 tctaaactca tcattgttgt ttttttcgtt ttaggattca ctgtcatcaa gatcatgcta
     3421 tcacttctac cgacccaagt ttcagttcgt tcaacatttc cggtgtccac tcccattaac
     3481 agaatggtta gaggttcagt cgcttcaata accttggttt cttcgccgat ttttttatag
     3541 gttttagcta aggtttctgt cccttgttga taaatagtat aagcaaaaac acctactcct
     3601 actacagtta cagaaagtaa agctagcacc attccaataa tttttttaac catatttcta
     3661 ctaacctatc agtttaccca tcaagtaaac atcgataaat ttcccttctt ctatatatgc
     3721 cccacgctct tggctacctt caatgacaaa gccatgcttt tgataaagat ggactgctgc
     3781 ttgattacga gtttggacag tcagttggag acgacgcaga atgccacttg cttgtgccca
     3841 ctctatcgct tcttctagca acaaacttcc caagccatta ttccaatatc tttttccaat
     3901 cacaatgaag agatctccaa tatgacggac tctcttacgc tggtcagctg taatatttac
     3961 aataccagca attttgccat ttaagaatgc aagtaaggtt atctgattgt ccgaactagc
     4021 ttgcttgttg aggaatattt ccatctcctc actagtcaag agaataccat ctccgtctag
     4081 gctggtaaag tctgtctcca aactcacacg atttaaaaag gccactaatt cagctgcatc
     4141 tttgggctct gcttccctaa tgagcaattc atactccata ttgaagctcc tctaacaatt
     4201 tctcagcacg caaacccttt gcctgaaaat ttaaacggcg tccatctgct tcttttagaa
     4261 tttccaattc taaataagca tctggcaagg catctcctaa gagatttccc cactcaataa
     4321 cagtcacgcc gccaccaaag ataaactcat ccaagtcgat agaatcagca tctccttcaa
     4381 tacgataaac atctaggtga taaagtggaa gtcgaccttc atactctctc acgatagtat
     4441 aggtgggact tttaatcatt tgagaaatct gtaatccttt tgcaagtcct ttagtaaagg
     4501 tcgttttacc tgcacccagt tctccagtta agattaaaac atcattcttt gctaatagat
     4561 ggcccaaacg ctcccctaag gcttgcaact cttcttcatt ttttgtgtac atactcttat
     4621 tataccaaaa acttttcttt tgtgtctatt ttcctactaa acttatcatc ataacatcca
     4681 taaaaaacag gctttctcta aaagaaaatg agcgtaacaa tgaccaatac aagatctcgg
     4741 aaaatatgac cataaaagga aacttccttc ttaaccgaat ttgggacaag ataggctgca
     4801 aaaaacaagc ccagtccaat ataaatcaga agtgagacaa tggtcattgg atttcttaag
     4861 aaaagaagtg ttgctaaaat agtcaccaac actgtctttt ttctgtctag catagcaaga
     4921 aaatcgcgca cgtatttttt caagggtaaa aaaatcagca aatctagccc aaataggaaa
     4981 aagaaggatg gcaataaaaa gtcaactaat tcttgctgca gcgtattttt gatgaacaag
     5041 ttatctgaca aaacaagaac agctcctaac aaattaatta agagtaacat actgtaaaaa
     5101 agcttcaccg acttcttact ggctaggaca ctatggactt cttgcttacg ggtataaaga
     5161 taatttactc cagcacagat tcctgaaacg aaaaccatgc ttccgatgaa aaaagctgta
     5221 ctttgtttaa aggacaagat gcattccttc cataggaaac agctactcaa actgatttga
     5281 attaaagcta acaaaaataa gattctcatt gatttcatct tctctctccc ttcctaccaa
     5341 tcattatact aggagaaaag agagaactgt ttctaatctt ctcaaatgtc tctttaagac
     5401 gctaaacaaa cactagagac taatactcaa tgaaaatcaa agagcaaact aggtagctag
     5461 ccacaggttg ctcaaaacac tgttttgaga ttgcagatag agctgacgtg gtttgaagag
     5521 attttcgaag aatataaatt tgaaatcatg aaaatccgtc aaacgggtgg ttgttttgtc
     5581 tcgcacctca cggagcgaga cggactcaga gtcacataat tataaggctg atagtattaa
     5641 tctaactatc agccttacag gttatttaac gtttcagaaa aactataatg tcaagattaa
     5701 ctaaacagta tctagttcct tcaaataatt ttctatcttc atcaacatta aaggattgtt
     5761 ataaatctta cataactctc ttgcttctat ataataattt ttgacttgtt ctctgtctag
     5821 aaatttggct ccagcatttc ctacaagaat aagtagagga gccaattggt agcttgtctg
     5881 tctttgttta cagagttcaa tcgtttcaag agcttcttgg atggcttcat tatatttttc
     5941 ctttgatact aggtagtgag cgtagttgta acgaactctg atgtaggcaa ataaaaactc
     6001 ttgatggtcc aaattttttg tctgatacaa ctctattaaa tgagagtagt ttgcctcata
     6061 ttcttgttca cgacccacta aggaatagaa attagataga gtattcaacg cctttaaata
     6121 aatcagagta tttgaagaga cttttaataa tatattttcc aatgaagaaa ttgcctcaca
     6181 cttactgtca tattgataga agtcaataat agctttaatc cattcaaggt aagttcggtc
     6241 ttctagtgtt agaaaagtac ttcgttcaat ctctattcta taaatatatt ccaaatcgtc
     6301 ataatttcta tcgtctaata gtcgagcaga caattgcttg aaattagaga ggttagattt
     6361 aatttcaatt tgttcattaa aaaaataatc taatggtact tcaagtcgtt gagagagttt
     6421 gaacaaaagg tctgcggagg gaatgaaatg ccctctctca attttactaa tctggctttg
     6481 ttcacaaatt ccttctgcaa gagtttgttg ggagagtctc aactcttttc ttttcaatct
     6541 gaatttctct gcgagtgtat tcattaaaga taataaacct tcctatttgc ttaattgcat
     6601 tataaaattt ttagttcaaa atagcaagtt aaaggaataa ataattcttt atggtaataa
     6661 actaaaaaaa gtcaaaaatt acataaaaat gcttgaccga ataatatata tatattaaaa
     6721 taaaaacaag gaaaaagaaa agggtttcac gaatgaagaa aaatcgtgga attcaaaaat
     6781 tagctatatt agtattacta gatgttttta tgtttagtaa cacaattcct taccaacagt
     6841 ttattcagaa gaatagacaa ttggagattc gagtgcaatc acaaaagaag tccaatggtc
     6901 ttgatgttgg gaaggctgat tgatttcgta ttactttaaa attcaactat ttagagaaag
     6961 gtattctgat gagagcttgt aacaatacca gatagatata agaatggaga tgtttgataa
     7021 aatgctttca tagctaacca actgttgaaa attatgagtt acaaaatcta aagtatttaa
     7081 gattggttta taaaattagg tctctgcctg tagaaaggaa cgtgcagtta gaaaggagga
     7141 aaaaatagga tactataatt cagactgaga tttctaatta aaatatgtag ttgcatttcg
     7201 ctcattttca taatatttca ttcagaggag taataatatg ttaaaattta catttgatgc
     7261 gggatggtaa agaataattg aagaagattc ttttatcaat agtttagtaa acttgttagt
     7321 ttatagaggg taggcgtatt tctgccctct gttttagaat aaggaatgca ctatgaaaaa
     7381 attatttata ctcatatcca acctgcttgc tagtttgttc tttgtttggg tatttaccat
     7441 ttggactgat acatatgtct cctattatta ccccaacgtt gttgtacatg attcttcccc
     7501 tgaaacaact tttcagcatg ttgctacacg cttggaaaaa ctagcagaag aaacagatag
     7561 ctttattgcg attcaacacc aagatcctaa ctcagaaggt actacagttt tttcttatac
     7621 aacctttggg gacggaaagt tgcctgatgg gcttcaggaa aaaaaactag aagatgctca
     7681 aagtagtagt gttgaaacaa actattttgt attcgatgga cacctagata ttcacttgct
     7741 aagggaggag ctaagtcaac ttggcttgac taatatgaac ctgacaattc catctaaact
     7801 atctacgtta atggctatct ttagtaacgg atttcagtta atcagtctat tgattttcat
     7861 cttaaccttt gtagcactga ctttaattag tcaaattagc caattacggt cgtcgggcat
     7921 tcgcctcatt tcaggagaga aacggtggtc cattttcctt agaccagttg gtgaggattt
     7981 gaaagggata gctgttggtt tcagtttagc tggcgtgctc gccattctta tgcaaaaaat
     8041 tctgtcgctt ccaacgcaat ccctaatgac cataggagca ggcttgctca gttataatct
     8101 catcttgttg tcgatctccc tgtttttcgc tcaactcttc gcagttggga taaaaaagat
     8161 acacctgatg cagattataa aagggcaagt gcctgtcaga ggaatcatta gtttgatttt
     8221 aatcggtcaa ctattagcga ttattattgt aacgctggga atagggagta gcttaaagta
     8281 ttcccaagcc tggcaacagc atcggattgg acaagaggtt tggagtcagg aaaggcaact
     8341 gattacccta tcaatcagcc gtgaaggaac gagtcctggt tttgatgaac aagctcaaag
     8401 gaaactcaga acttggtatc aattgatgga tctggctgtt tcagaacaaa aggctttctt
     8461 atctagacac cagttaattg accgtacttt gcaaaatggc atggcttcct ccaaaaactt
     8521 gataacctct acagaatggc acgattacaa cccgaatggc aatgtcctta tcgtcacacc
     8581 gcaatacttg gagcgtcaaa acattcctgt agatacaact attgagcaaa agatgaatca
     8641 ccttgatgta ggggagtttg tcttattgct gcctgaacac ctccgttcag aggaagaaca
     8701 ttataaatct gtttttgaag acgacttaac cagtcgcatg tctagtcaag atgaacgaca
     8761 gcaaatgact gctacggtag gttatttaga atcaggtcag gatcgttttg tgtataatac
     8821 gacccctatt tcttaccagc agtttttgaa agatccaatc atcattgtta taacacccca
     8881 atcaactggt ccacagtcca ttttgttttg gatagacgca gtacagaact acgttctctt
     8941 taatcaattg tctgatgccc aggagcttat ccagagacaa ggcattgaaa attgggtctc
     9001 agaaatgcaa acaggttacc acaactacat cacattattg gataatatcc agagggaacg
     9061 ttgggtaatg ctagcaggag ctgtgcttgg gattgcaact tcaatcttgt tgtttaacac
     9121 tatgaatagg ctctactttg aagaatttag acgtgccatt tttatcaaac gcattgcagg
     9181 tctcaggttc ttagaaatcc atcgcactta tctctttgct caactgggtg tgtttttact
     9241 gggatttgtt gcgagtgtat ttcttcaggt agagatagga gttgctttct tagtcttgtt
     9301 actctttact ggtctatctc ttttacagtt acatgtccaa atgcagaaag aaaacaagat
     9361 gtccattctt gttttgaagg gaggttaata tgattgaact taaacaggtg agtaaatctt
     9421 ttggagaacg agagttattt tcgaatcttt caatgacatt tgaggctgga aaagtctatg
     9481 ccttaattgg ttcaagtgat agcggaaaaa caaccttgat gaacatgatt gggaaattag
     9541 aaccttatga tgggacgatt ttttaccgag gtaaagactt ggccaattat aaatcgagtg
     9601 attttttccg tcacgaattg ggctacctct tccagaactt tggcttaatt gaaaaccaaa
     9661 gtattgaaga aaaccttaag ctaggtctca ttggtcaaaa gttgagtcgg tcggaacagc
     9721 ggttgaggca gaagcaggct ttagaacagg tcggcctggc ttatcttgac ctagataagc
     9781 gcatctttga gttatcgggc ggagaatcgc aacgggttac cttggcaaaa attatcttaa
     9841 agaatccacc ctttattctg gcagatgagc caacagcttc aatagaccca gcaacctctc
     9901 agttgattat ggagattttg ctatctcttc gagatgataa taggctaatc attatcgcaa
     9961 cacataatcc ggcaatttgg gagatggctg atgaagtgtt cacgatggat catctgaaat
    10021 aaaaatcctt gtttttaatt gcacgatgag ttactgaaat attatcatga atcaagaatt
    10081 ggagttaatt tagaattgta ctttattaat attgaggtaa ctttttcttg ataaaggaag
    10141 aaataatgga gaggaagtta gaatgaaaaa attcgacaat tatattattg agaagccttg
    10201 cgattctaat tcagataaac tgcaaaaaat cttaataatt gaaagtttgg tagatgatat
    10261 tttgcaattt tctctcagaa tcaataatag tgtaggagag attttcctcc tacaaccgtt
    10321 ttaaaagaaa actatcttta ttccatgtta ttttgaggaa gatattgtga aagtcaaaga
    10381 tgatgataaa gttgagtgga atttgttaga atttcaaaaa tttagagcat ttttggctta
    10441 gtaatctgtg ttgaaggctc aaaacctatg gtaaaaaagt agctttgaaa acgtattgcc
    10501 tccaaagatt tagttaaata atgatttaac acaaaaagaa attattgaag ttctggaaag
    10561 atgttgtttc agtattgaga aaaggtggga aaaacttgcg attttcacag agaaaggaag
    10621 aaaaagtata gaaatatagt caattgaaac aagaacagga taaaagaacc ttttgtgcca
    10681 tatttttctc ctttcgcttt acaattggat tgaacacctt tattgtatcg cgtttggagt
    10741 ttttttggta taaccttcga cgcgcacccg catagcgggt gtttttttgt ctcgcaccta
    10801 acggagcgag acaaactaat agtcacttaa tcaaaaaacg caccatatca aaaactaaaa
    10861 agtttgatat catgcgtcat gtcttaaact aattgactat actttctatt caaatgagct
    10921 tttaaccaat tgattgagcc aatccactct taaaaccaaa gagcaatttc tcgcttagct
    10981 gactcttctg aatctgaacc atgtacaaca ttttggataa tctcattttc tccagcagct
    11041 tttgcaaaat cacctcgaat agtgcctggt aaagcttctt ctggacgagt tgcacccatc
    11101 atggtccgcc aagtttcgat tactttggga ccagaaatga cacccacaag aactggacct
    11161 gaagtcatga attcacgaat cggtgggtaa aaactctgac caaccaagtc ctgatagtgc
    11221 tggtcaatca actcttctga aacctgtgaa cgaaactcca atttttcgat tgtaaatcca
    11281 cgttgttcga tgcgctttaa cacttcaccc actagccctc tttttacacc atctggtttg
    11341 atgataaaga atgtttgttc catacccgtc tcctttgtca gcttctttct tttattttac
    11401 cacatttcgt ggaaaaatgg agaaagtttt cagaagagag aatgagagaa ccctcgggtt
    11461 ctctcattct ctcttattct actgtttctt ccacagtttc aacggcagta tccacaacta
    11521 cttctgttgt ttcttcattt ccttcttcct ctactggagg attaaggtat tcttcttcgt
    11581 tgacagcatg tggttcaagg ttacggtaac gggccatacc agtaccagct gggatgatct
    11641 taccgatgat aacattttct ttaagtccaa ggagatggtc tttcttacca cggatagctg
    11701 cgtcagtaag gacacgagtt gtttcctgga aggaagccgc tgacaagaaa ctgtttgttt
    11761 caagtgaggc tttggtaatt cccataagga ctgggcgacc tgtcgctgga actccacctg
    11821 cgataaggac atctttgttg gcatctgtaa agtcattgat atccatgagg gtacccatga
    11881 gaagatctgt atcacctgga tccatgacac ggactttacg gatcatttga cgaaccatta
    11941 cctcgatgtg tttgtcaccg atttctaccc cttggctacg gtaaactttt tgtacttcac
    12001 cgagaaggta cgtttcaact gacaagacat cacgaactgc aaggagacgt tttggttgga
    12061 tagaaccttc tgtcagagca gcaccacgcg ctacttgtcc cccaacttcg acacgcatac
    12121 gagctgtaaa tggaacgaca tattcacctt cgccagtttc acccttaaca aagactttct
    12181 tggtacgagt tgatgcatct tcttcgatag cagtaacttg tcctttaacc tctgtaataa
    12241 ccgcttcccc tttaggattg cgggcttcaa agatttcttg gacacgagga agaccctgag
    12301 tgatatcggt atttgaggca accccacctg tgtggaaggt acgcattgta agctgtgtac
    12361 caggttcccc gatagattgg gcagcgattg taccaactgc ttcaccaact tcaaccgcat
    12421 caccagtcgc caagttgata ccgtaacagt gacggcagac accgtgacga gtgttacatg
    12481 taaatacaga acggatagtc acttcttcca caccagcatt gacaatttca cgcgccttgt
    12541 cttctgtaat caattcattt ggaccaataa tcactgcacc agtttctgga tgtttaacag
    12601 ttttcttagt gtaacgaccg ttgagacgct cttcgagaga ctcgatcatc tcttttcctt
    12661 ctgcgataga acggatcaag agaccacggt cagttccaca gtcgtcctca cggatgataa
    12721 cgtcttgggc aacgtcgacc aaacgacgag tcaagtaacc tgagtcggct gtcttaaggg
    12781 ccgtatcggt cataccttta cgagcaccgt gagttgagaa gaacatttcc aataccgaca
    12841 aaccttcgcg gaagtttgaa aggattggca attccatgat acgtccattc ggagcagcca
    12901 tcagaccacg cataccggca agctgtgaga agtttgagat gttaccacgg gctccagagt
    12961 ccatcatcat aacgattggg ttcttaggat cttgattagc aatcaagcgt ttctcaagtt
    13021 tttcacgggc agcacgccat tcagctgtaa cagcattgta acgctcgtca tctgtgatca
    13081 taccacgacg gaattgtttg gtgatttgtt cgacacgttt gtgtgattct tcaatgattt
    13141 cagccttgtc atcaacgact gggatatcgg caatacccac tgtcaatcct gcaagagttg
    13201 agtggtggta accgaggttc ttcatgcggt caagtagggc agaagtttct gtcgtacgga
    13261 aacgtttgaa gatttcagcg atgatatttc cgaggttttt cttcttgaat ggagggttga
    13321 gctcaagatt gctgatagct tccttgatat ctccaccaag tggcaagaag tatttagctg
    13381 gaacaccttc tgtcaagttg gcattgtttg gttcttgcaa gtatggtagc ccctctggca
    13441 tgatatcgtt gaagagaatt ttaccaactg ttgtaagcaa gaccttatgt ctttgctctt
    13501 ctgtccaagg cttgttgagg ctgtctgttg cgataccaac acgtgagtgg aggtgaacat
    13561 aaccattgcg gtaagccata accgcttcgt cacggtcttt gaagaccatt ccttcacctt
    13621 cgcgaccagc ttcttccatg gtcaagtagt agttacccaa aaccatgtcc tgagatggag
    13681 taactaccgg tttcccatct ttcgggttca agatgtgctc agcagctagc atgaggatac
    13741 gagcttctgc ttgtgcttct tctgaaagtg gtacgtggat ggccatttgg tccccgtcaa
    13801 agtcagcatt gtaggcttca cagacaagtg ggtgcaagcg aagagcctta ccatcaatca
    13861 agactggctc gaaggcttgg atacccaaac ggtgaagggt cggtgcgcgg ttcaaaagca
    13921 ctgggtgttc tttaatcact tcttcaagga tatcccagat acgctcatct ccgcgttcca
    13981 ccaagcgttt agctgctttg acgttttgca cgatatcacg ggcaacgatt tcacgcatga
    14041 caaatggttt aaagagttca atcgccattt cacgtggcac accacattgg tacatcttaa
    14101 gagttggacc aacggcgata acggaacgtc ctgagaagtc aacacgttta ccgagcaagt
    14161 tttgacggaa gcgtccttgt ttacctttaa gcatgtggct caatgatttc aatggacggc
    14221 tacctggtcc tgtgattgga cgaccacgac gaccattgtc aatcaaagcg tcaactgctt
    14281 cttgaagcat acgcttctca ttttgaacga tgatacctgg tgcatttaac tcaagcaaac
    14341 gagccaaacg gttgttacgg ttgataacac ggcggtaaag gtcattcaag tcagatgagg
    14401 caaaacggcc accatccaac tgcaacattg gacgaagatc tggtgggata accggaagga
    14461 tgttaagaat catccattca ggtttgtttc cagacttgta aaaggcatcc aaaacatcca
    14521 aacgacggat ggctttgaca cgtttttgtc cagtagcagt tttcaattct tctttgagtt
    14581 cagcaatttc tttttcaaga tctacttgct tcaaaaggtc ttggatggct tccgcaccca
    14641 tcttagcaac aaatgaacca taaccatatt cacgcaagcg ctctcggtat tcgcgctctg
    14701 tcatgataga cttgtgctca agtggtgtat ccttaggatc aatcaccaca taagccgcaa
    14761 agtagataac ttcctcgagg gcacgagggc tcatatcaag ggtcaagccc atacggcttg
    14821 gaatcccctt gaagtaccag atgtgagata caggagcttt caattcgata tgtcccatac
    14881 gctcacgacg aactttcgta cgcgttactt caaccccaca gcggtcacaa acaattcctc
    14941 tgtaacgaat gcgtttgtac ttaccacaag cacattccca gtcttttgta ggaccaaaga
    15001 tcacttcatc aaagagtcct tcacgttctg gtttcaaggt acggtaattg attgtttcag
    15061 gttttttgac ttctccataa gaccatgaac ggactttact tggagaagct agggtgattt
    15121 gcatactttt aaaacgattt acatcaacca ctatttcttc cctttctatt ctaagtgaac
    15181 tgcttattct tgttcagcag cttcttctgt tgcttccgct tttgttgctt tctcagcttc
    15241 ttcagcttca aaggctgctt tagcctcttg ggctgctttt tcgcgggctt tttcaaggtc
    15301 atctacgtgg atgacatctt cgtccattcc ttcatccaag tcgcgaagtt ccacttcttg
    15361 gtcatcttcg tctaggacac gcatgtcaag accaagagat tgcaattctt tgacaagaac
    15421 tcggaaggat tctggaacac ctggttttgg aattggtttg ccttttgtaa tagcttcata
    15481 ggctttcaaa cgtccgttga tatcgtcaga cttgtaagtc aagatttctt gaaggacatt
    15541 tgacgcaccg taggcttcaa gagcccaaac ctccatctca ccgaaacgtt gtccaccaaa
    15601 ctgagcttta cctccgagtg gttgttgggt aacagttgaa taaggtccga ctgaacgcgc
    15661 gtgcaattta tcgtcaacca tgtggtggag tttgatcatg tacatgactc caacagaaac
    15721 acggttatca aatggttcac ctgtacgtcc atcgtaaagg attgtcttgg catcgctatc
    15781 catacctgct tctttaacag ttgaccaaag atcttcagaa cttgctccat caaagactgg
    15841 tgtcgcaatg tgaataccaa gagtacgagc tgccatacca aggtgaagct ccataacctg
    15901 accgatattc atacgtgatg gcaccccaag tgggttcaac atgatgtcga ctggagttcc
    15961 gtctggaagg taaggcatgt cttctacagg aacgatacga gagacaaccc ctttgtttcc
    16021 gtgacgtccg gccattttat ctccgacctt aatcttacgt ttttgagcga tgtaaacacg
    16081 aaccaacatg ttaacacctg attgcaactc atctccattt acacgtgtaa agatcttaac
    16141 atcacgaacg acaccatcgg caccgtgtgg tacacgaaga gaagtatcac gcacttcacg
    16201 agacttgtct ccaaagatag cgtgcaagag acgttcttca gctgaaagat ctttctcacc
    16261 cttaggtgtt actttaccta caagaatatc accttcttta acctcagcac caatacggat
    16321 aatccccatt tcgtcaaggt ctttgagggc atcttcacca acgtttggaa tttcgcgagt
    16381 gatttcttca ggcccaagct ttgtatcgcg cgtttctgat tcgtattctt caaggtgaac
    16441 agatgtgtag acatcgtcct tcaccaagcg ttcgctcatg ataacggcat cctcgaagtt
    16501 gtaaccttcc caagtcatgt aggcaacgat tgggttttgt ccaagcgcca tttctccatt
    16561 ttccatagaa ggtccgtcag cgatgaaatc gcctttttca acgacatcac caacttttac
    16621 gagagtgcgt tggttgtaag cagtacctga gtttgaacga cggaattttt ggatgtggta
    16681 aacatccaat gaaccatctt cacgacgaac ttctaccttg tcagcatctg cgtaagtaac
    16741 tttaccatca tactgagcaa tcacagccgc accagaatcg tgggctgctt ggtattccat
    16801 accagtacca acgtaaggtg cctgaggatt aatcaatggc acagcctgac gttgcatatt
    16861 ggctcccatg agggcacggt tggagtcatc gttttccaag aaaggaatac atgctgtcgc
    16921 aacggcaact acctgttttg gtgaaacgtc catgtagtca acaatattag ctggatactc
    16981 ttggttgacc ccttggtgac gtcccatgac aatcttctca gcaaaggttc catcttcatt
    17041 cagacgagag ttagcctgag ctacagtata ttcatcttct tcatcagctg tcaaccaaac
    17101 aatttcgttc gtgacaacac ctgtttcacg gtcaacctta cggtatggtg tttgaacaaa
    17161 accatatttg ttcaagtgtc cgtaagatga caagttattg atcaaaccga tgttaggtcc
    17221 ttcaggtgtc tcgattggac acatacgacc atagtgagtg tagtgcacgt cacgtacttc
    17281 atatccggca cggtcacgag tcaaaccacc aggtcctaag gctgacaaac ggcgtttgtg
    17341 agacaactca gaaagcgggt tgtgttggtc catgaactgt gacaactgtg atgaaccaaa
    17401 gaattcttta accgcagctg ttacaggacg gatattgata atttgttgtg gtgtcaagac
    17461 ttcattgtcc tgaacagaca tacgttcacg gacattacgt tccatacgag aaagtcccaa
    17521 acgtacttgg ttggcaagca attcaccaac cgcacggata cgacgatttc caaggtggtc
    17581 gatatcatct acacggccaa gtccttcagc caagttgagg aagtagctca tctcagcaag
    17641 gatatctgca ggagtcaccg tacgaacctt gtcatctggg ttagcattac caatgatcgt
    17701 tacgacgcga tctggatcag ttggagcaac aaccttgaat ttttgaagaa caacaggctc
    17761 agtcacaacg gctgcatcgt ttgggatgta gacaatcttg ttcaagtcgc catccaaatg
    17821 gctttcaatg ctttcaatca cgctacgagt cataatcgta ccagcttcta ccaagatttc
    17881 tccagtttca gggtctacca atggctctgc aatggtttgg ttgagcaaac gtgttttaac
    17941 attgagtttt ttattgattt tgtaacgacc aactgctgcc aagtcatagc gacgtgggtc
    18001 aaagaagcga gccacaagca agctacgtga gctttcagcc gtcttaggct cacctggacg
    18061 aaggcgttcg taaatttctt tcaaggcttc gtctgtacga gagtccattg gattcttgtg
    18121 gatatctttt tcaacagtgt tgcgaaccaa ttcgctgtca ccaaaaatat caaagatttc
    18181 atcatcacct gagaaaccaa gagcacgaac caaggttgta aatggaatct tacgagtacg
    18241 gtcgatacga gtgtaggtga tatcttttga gtcgctttca agttccaacc aagctccacg
    18301 gttagggata acagttgaac catagcccac cttaccattt ttgtctactt tgtcgttaaa
    18361 gtaaacacct ggtgagcgga ccaactgaga aacgataata cgttcaccac cattgatgat
    18421 gaaagtaccc atttctgtca tgattgggaa atcaccaaag aaaacttctt gggtcttgat
    18481 ttcgcctgtt tctttattga tcaagcggaa ggttacaaaa attggtgctg agtagctagc
    18541 atcgtggata cgagcttctt ctagcgtgta ttttggttcc ttgatttcat atccaacaaa
    18601 ttccaactcc attgtgtctg tgaagtttga aattggcaat acatcttcaa acacttcctt
    18661 aagaccgtgg tctaggaaag ctttgaatga gtcagtttga atttcaatca aatttggtaa
    18721 gtcaagaact tctttgattc ttgaaaaact acgacgggta cgatgtttcc cgtattgaac
    18781 gtcatgtcct gccaagatga ttctcctttg taaataagtt ccaagccttg tcaatcaggc
    18841 ttttctaatc gccatatggt tgtaaacccc ttatcaccgt gtcctcttga cgaattttca
    18901 gaatctttaa gcctctgtta caaatgctca aaatcttgaa aaaaagcaca aaaagagcag
    18961 ctaaatctga ctttttcaga agatttaact gctgtgagcc ttgtctggac aatatttcag
    19021 acaaaaccta cgacaaatga ttacccatat tataccctat ttagctagat ttttcaaggg
    19081 gtttcagtag gtttttggta aattttttcc catagaaaac ttggcatcac attcgaatca
    19141 cgctatggta caaaaaactg aaaaaactat tgactgaaaa tcattttcaa ggtataataa
    19201 taaacgttaa ggcggtatag ccaagtggta aggcacggct ctgcaaaagc ttgatcgtcg
    19261 gttcaaatcc gtctaccgcc ttctataact tgatttatca ggtttcaaat gaacagaaag
    19321 cccaatttga agggcttttt ttattttccc tcgaataaat acgtataact ttaaaaactt
    19381 ttggagcgag tttgtggcag agttctttcc atggcataat tcccttttga aatcaattga
    19441 aaaaagcttc gtcacgcctg gtgacaaaag cctctagttt attctgtttc ttcttctatt
    19501 tcgacttctg tgatttggac ttttaccttg gtaacacgtc cattcttcac tttatcattg
    19561 gttaagataa actgtttgtt ttggctgacc aattcatagc tgagtttctc agtcgttgga
    19621 atggttccca ctcctgtcaa ataataacca gcgatggtat caacgtcatc actttccagt
    19681 tcaacatcaa agtaattatt gaaatcattg agggtcatag ttccttgaac aatgtaggta
    19741 tcctcgccaa tctgatgaac atctattgct gctttgtccg tttcatcatc aatttcacca
    19801 acaatttcct ctaagaggtc ttccaaagtc accaaaccag ccataccacc gtattcatcc
    19861 agcaagattg ccatttgtct ttgggtattt cgcagttctt ttagcaagtc atccacaaaa
    19921 atagtttcag gtacaaaaag tggatcttgt aaaattctct tccaaacaat attgtcaaaa
    19981 ccgtccacaa agcctgcctt aaggagactc ttggtgtgaa tgattccaat tacattgtcc
    20041 ttatccccat cataaaccgg gatacgagaa taattttgtt ttaaaatact ttggataatg
    20101 gcttgactat catcctgaat atccaccata aaggcatccg ttcgaggaac cataacctct
    20161 cgtgccatca gttcatcgag cgaaaagaca ccttgtagca tctcaatctc atcagcatcc
    20221 aatgtttctt cactatttgt cagcatatag gcaatttcat cacgggtcat cttttcatcc
    20281 gcatcatcga atgacatagg agtcaaatgg ctcaagaaat tggtcgaagc agctaaaagc
    20341 caaacaaaag gactgactag ttttccgatc ccaatgataa tcggcgctgt acgaattgcc
    20401 aaggcatcct ttagattaag agcgattctc ttaggatata attccccaaa aacgatggaa
    20461 atataggtca aaaatgccaa ggatagaaaa gttgccacgg cttgtgctgt ttcgccattc
    20521 ccaagccaag aggcaatcac acgtcctaga gtatcagtta aactcgcccc tgataagatt
    20581 gtaatcaggg tgattcctac ctgaatggtt gataaaaagt ggttaggatt ttctagtacc
    20641 ttcagcaggc ggatgtagcg tctgtctcct tcttccgcct tttgttcaac tcgggcacga
    20701 ttaagagaaa ccatggccat ttctgtggct gagaaaaagg catttaatac cgtcaagata
    20761 aacaataaaa caaattgtag caacaaattc tgactacttg ggtcttccat agttcttctc
    20821 ctaaaatagt atcttatcct ttattatatc acaaaattta atccaataca tattattttt
    20881 ttcttagcgt aacttccatc tctctcccaa aactggaagt tagtctaaga cggatttcca
    20941 ctgatttcac gcgtttttct catactaaaa gctaggttgt gggaaactgg aagttagttt
    21001 tagaagttac tattttttct tagtacctgt tctagccctg cttaaactag taaaaagaac
    21061 tcctacatcc ataagtgaca taggagttta ggcttatctt ttactgagtt acagttactt
    21121 ctccagttcg gtaatccagt tgaagtccct tttgaacatt gggaactaga acattgaatt
    21181 ccaattctcc atccgaagac ttggcttcaa tctgtgaagc tgagggaact aaatcctcgt
    21241 ttgaagcgta gtaaagggtt acacggtaac ggacacgctt gttttggtcc aaggctttac
    21301 gcaccttgct ttcatagtag ttttgaccag tcgaatactc ggcttgtgcc tgatttgccc
    21361 aggctgtctg aacagcaatg tttttaggat tgcttgttga ggcatcaaaa ccatccaaac
    21421 caccgattaa ggcatagcct aacaaatgac ctctatcgac tgcatgggta taagagccct
    21481 ttagattctt gacctgatgc caacctggag gagtccaaga agttgaacca ttcccagttt
    21541 ctttacgatt cttgtactga cgagtggcct tagacaagag ggcattagct acggttggaa
    21601 cagtttcctt gcccactgtc tttgttttat tgtcagcgta gggcttactt gaaaccttgg
    21661 catctagatt tgttttatta ccattgacga taaaagcacc tgagccattc cactccagac
    21721 tcccctttat ttgactcttg actgcgtctg ttaagacact ctctgccaat gcttgactag
    21781 gagcttcagg cccttgtttt ttctgactaa gattggtttt gggactatta ggtgccgact
    21841 gcatctgctt gatataatag ctccctgtag acaaaagcaa taacactagc agtccgatta
    21901 gtgtctgtct tgtttttttg ttcatatttc tccttatctt tagaaaaagg ctggttctcc
    21961 agcctaattt cctgtaaatt tatgaatcaa ttcctgccat tttgctggag acaggatagc
    22021 ccatggatct tgacccttgc ccaagattcc ataacctacc attagaccga ttcctagagc
    22081 cagagtacct aaaatcagta ctatgatgac taaaagtaaa cgattgatta cgtagcttga
    22141 tttcttattc atcttcatcg cttgcctcaa tccgctgaat cttagcacct agctgcgcca
    22201 acttctcatg gaaaccgtag taacctctat ccaagtgaac caatttaccg accacagttt
    22261 ctccctgtgc taccaaacct gtcaaaatca aggctgcact ggcacgaagg tcagttgaaa
    22321 gaacttctgc tccctgcaaa ggctgtccac caacaatacg agctgtatca cggataatct
    22381 cagaatgcaa gcccatgcgg cgcatctctt ctaggtgttg gaaacgattt tcgaaaactg
    22441 tctccaccat ggttgattcg ccttttgcaa ctgtcatcaa ggctgtaaat tgagcctgca
    22501 tatctgttgg aaatcctggg tggggcaagg ttttcacatg aacagctttt agattttcta
    22561 gttgagaacg aacacgaatt ccttcgtctt cttcaattac ttcaacaccc atttcaagta
    22621 acttggcaat caagggacgg ttgtgctccc agacagcgtc tcgaatcaag acatcaccac
    22681 cagtcatggc agcagctacc ataaaggttc ctgcttcgat acggtcttgg actacattgt
    22741 gagtcgtacc atgaagtttc tcaacaccag taatggttat agtctctgta ccagcacctt
    22801 tgaccttggc tcccatttca ttaaggagaa tggctaagtc aacaatctca ggctcacgcg
    22861 cagcattctc aatcactgtc accccatcag ccagagtcgc tgccatcatc aagttctgcg
    22921 ttgcaccaac acttggaaag tccatataga tatgagcgcc atgcaagcgt tctgccttgg
    22981 cttcgatgta accagctgtc tgactaatct taacccccat agcttccaga cctttcaaat
    23041 gaagatcaat aggacggcta ccaatcgtac aaccacctgg catggatacc ttggcatgac
    23101 ccacacgggc aaggattggc cctaatacaa cgatggaggc gcgcatcttg ctgacatact
    23161 tgtaaggggc ttcctcagtg atgtcgccag tagcatccac cttgacaaga tgagcttcct
    23221 catcaaagtc aaccttggca ttcaaaccac caactacctg attcataata aagacatccg
    23281 acaaaatcgg aacattctgc aagacggtct ttccttcact tgctagaata gtcgctgcca
    23341 acaagggtaa gactgcattt tttgctccct cgatcgtcac gcttcctacc agacgattat
    23401 cgccaccttg aaccacaatt ttatccatac tcgtttcctt tactcttgat ttcataataa
    23461 tcctctaagc gcttcttgcc acaaatgata caggctaata aagaaagaac tcaggatgta
    23521 gcctatgaca atgctaaaaa aggctactaa taaacgaact tttcttgtat tatcatctgt
    23581 cacttttaaa accttctccc atctaacaag atcctttaaa aggtaaaaac tcacataaat
    23641 aaagaacata tgactactta gagtgaataa taattgaacc atttgactat tataccatct
    23701 tctctgtttg tgcgctagtt tggaaacttc actcaaaaat tagggattgt ttttcaagta
    23761 atcaatcgca tcttgtaggg ttttaacggg cacgattttc atatccgtct tgattgtttt
    23821 agccgcttct agggctgttt ggtagttgtt tttcgcgtcc ggatgcgcct tttgttcttc
    23881 ttcgctaaca gggttatcag gagcaaagaa aatagcagca cctgccctag ccgaagctac
    23941 aaccttctta tcaatacctc caatgtctcc cacattacca tcgcggtcaa tggtacctgt
    24001 accggcaaca atacgaccat tacgaagatc tgggtgagct atttgagtat agatagctag
    24061 actaaacatg agaccagcac ttggaccgcc aataccagct gttgaaaagc taattgggac
    24121 attgctgatt acctctgtac ggtcaatcaa gccgattcca attccatttt tgccattttc
    24181 caaggtgatg atttttcctt ctgcagactt ggtttgccca tcctcttcat aggtgacctt
    24241 gacggaatcc cctaattttt gagaactgac gtaatcaatc aagtctttgg aactatcaaa
    24301 ggtctgatca ttgactgctg tgactgtatc agagatattg agaatccctt taaaggttga
    24361 attatccgtc acattcaaaa cataaactcc aaagtacttg agttcgatat ccttaccagc
    24421 tgtttttagt ccttgatact tggccatatt ttgtgatgtt tgcatgtata attgattgat
    24481 tcgcataaat tcaacatcgg aagaaccacc tgtagtctcc tgagcactac gaatatctgt
    24541 aaaaggtgtc aaccaagcat aaatcatatg agctaaagtg gcatgttgaa caccaaccgt
    24601 aacgaattga taggcaccag cttccttatc ttctgtgtca tttactttaa ggacttggcg
    24661 aatatcttcc gaaccacctg gaacctctat ataataaggc aagggcacta caaatgccaa
    24721 gaaggtcaca atcaaggccg caatgacgta taagggccat ctaatctttt ttttcatttc
    24781 ttatttcctc caaaatactc tcgggaacat agcaggcaat atcctgacca aacttcaaaa
    24841 gctctctaac gcctgatgaa ctgatataga gatgttcagg tcgactatgt aaataaatag
    24901 tctctatatc agaagacagc tgatgattgt agtaatcaaa actggcttca tattgcaaat
    24961 ccgacgcatt tctcaagcct cgcactaggc aagtagcccc cagtcttttt gcgacatcga
    25021 ccaccaattt atcatgagaa gacacgactt taacatttcc caaatgtttc acagcctttt
    25081 ctaacccccg tttacgattt tcaagaggga gaaatccttg tttgtgggga ttaaaaaaaa
    25141 tacccacata aagcttatca aagagtctgc tcgcccgttc aatcatatcc agatgcccat
    25201 ttgtcatcgg atcaaatgag cctgtgaata agccaatctt atctgacata gactgtcacc
    25261 ttactaattc cataaatctt ttccttccag atacccagac aggcaatctc ttctggaagt
    25321 tcaacggcct tatccgtctc gcacacaacc ataacatctt cagaaaaaag ctctctctca
    25381 gccatttttt caatatctgc tacgatttgt tccttggcat agggagggtc taagaaaacg
    25441 aggtcaaatt ccccagatac ctgttccaat gccctttctg catccatttt gaggagttga
    25501 aattttccaa cttccttggt catctggata ttttcagcca cgatggtctg agccttacgg
    25561 tctcgctcca ccaaaacagc actggacatg ccacgcgata ctgcttcgat agataaacca
    25621 ccactacctg cataaaggtc caagactcgt cccacttcaa agtagggacc aatcatgtta
    25681 aaaatggctc ccctaacctt atccgaagta ggtcttgttg tcttgccttc tagtgtcttg
    25741 aggggacgtc ccccatagat tcctgatacg attttcatac tgtttattat accaaattat
    25801 agacaaaaag agaaagaaaa ccgaaccttg cggttcgatt ctctacaaaa tattttcgta
    25861 agtatcgcgg acttcttgag gccaaacact tgtttgcact tctccgatgt gtctcttgcg
    25921 aagtaggaac atggccatac gagattgtcc aattcctcca ccgattgtca atgggaatag
    25981 gccattcaac aaagacttgt gccattccaa ttctaagcgg tcttcatcac ctgtaatttc
    26041 cacctgacgt ctaagagttt cttcatctac acgaattccc atagaagaca actcaaaggc
    26101 tccacctaaa gactcattcc agacaagaat atcaccattt agacccttgt agccattctc
    26161 agactcgctt gtccagtcat catagtctgg tgcacgtcca tcgtgcggtt taccatctgg
    26221 caactcgcca ccgataccaa tcaaaaagac ggctccaaat tctttacaaa tcgcattttc
    26281 acgttcttta ggtgtcaagt ctgggtagcg ttctaccaat tcttctgtat ggataaaggt
    26341 gatttgtttt ggcaagatag actcgatgtc atagcgggct tcaacagcta gctcagtcag
    26401 gcgaatagcc ttataaatct tctcaactgt ttcttttaga taaacgatgt tacgcttacc
    26461 atttggaata accttctccc agtcccactg gtcaacataa acagagtggg ttgcatccaa
    26521 ggaatcctca tctggacgaa gggctttcat gtggacaaag agaccctctc cttcaccaaa
    26581 gccaaaacga gccaaggtgt ggcgtttcca tttagcaagt gagtgcacca cttcataagt
    26641 agcatcaggg atttggagaa ccttgaccga tactggattt tccacaccag acaggttgtc
    26701 ctgcattccg tcaccgacct tactcaagat aggaccttga acttcgacaa cttctagctt
    26761 atctttcaaa tactgggtaa aagtgttttt gacaaaggaa atttcttctt gttgatggat
    26821 aaaacttttc ttcatagaca actcctcaaa aatttaataa acgtattata cacctatttc
    26881 caagaaaaga aaagagaaaa tttaaaaaaa atcagtgtca ctcaaaacac tgatttcata
    26941 gaccttttag tcattgcgac caaagatacg tagaatactt aggaaaagat tgataaaatc
    27001 aagatagatg ctgagagcca ttgacaccac ccagcctgtc gctacacgac cttgtgattg
    27061 ttcataggcg aggcgaatct tttggttatc ccaagcaatc aaccctgaaa aaaccaaaac
    27121 catggctacg ctaatcatat aatcaaagaa gccactagcc aagaaaatat tgactaccat
    27181 agcaatcagt aaaccaatga gagctgccat cattgctcga ccaatcccac tcaagtcttt
    27241 cttggtaaag ataccaactg ccgccatgac aaagaagaga agggcgctcg atacaaaggc
    27301 agataaaact gtacccggag tatagaaagc caccacaaaa ccaagggtaa agccgtttaa
    27361 aacggagtaa agtaaaaata ctggaagagc agctggacta tttcttgaag ccatgctact
    27421 ggcaacgaaa accaaagcca actccgcaaa agtagcaatg gtcaaccaga gacgcccctg
    27481 catcaaaaag taaaccaact gagactgaaa gaccgtcaac ataaggcctg ataccaaagc
    27541 agatagtccg attcccagac caacaaaggc ataaacctta gcgtaaaatt gattgagacc
    27601 tgcacggtca tgtataatag tgtgattcat ccatttctcc ttttctgtga acatctttcc
    27661 ttgattataa caaaaaaagt taaaattagc ttaaatggaa gattaaaata ccggctgcaa
    27721 ccgcaacatt caaactctcg gcctgcccct tcatgctaat atggaccaac tggtctgcac
    27781 tttcagccat aaggggacta attccttgac cctcatttcc cataactagt acaaaatttt
    27841 ctatagaagg cagttctctg taatcaacag aatctttaga tagggttgtt gctagcactg
    27901 ggatagctac ctttttagtt tcgtcaagaa gcgcttgact agtcatccgg taaatgggca
    27961 gatggaaatg actaccttgc atggaacgta gggttttgag actgtagatg tctgccgact
    28021 tatctgaaac aatcactcct gtaaaacctg ctgcatccgc agttcgaatg atagttccta
    28081 cattaccagg atcttgcaca tcttccaaaa acaagaactt gccctgactc aaatcagctt
    28141 gtcctacttc ttctttttga accacggcaa caattccctg tggagtctga gaatccgcca
    28201 aatctagcaa aatatcctct gaaatccaga cagtttgcgg aaaagcagct aactgatttc
    28261 gataattttc tagggcaaag attttctcaa tcgtcactcc agcttggaca gcttcttcaa
    28321 acaagtgcca gccttcaatc aaataggcag acttgcggta ttttttttgg tgtaatttct
    28381 tagcattttt taccacagaa ttggcttttg aggttataat agtcatagaa atattataac
    28441 acaatcaaag gggtttggta tgcaaaaggt tagaatgatt gcccaaggta gggtgcaggg
    28501 agtcggcttt cgttggggtg tttatagcct ggcccttgaa atcggtggca tcacaggtcg
    28561 ggtatggaat aacgacgatg gcacagtgga aatcttagcc caagcagact catctgctat
    28621 catggcaaaa tttatccaag aaatccgaaa aggaccgaca cctttttcaa aagtaagcta
    28681 cttagatgtc aaactaagca actttcctcc ctactctgac tttaaaatcg caaattaggt
    28741 ctccagaact attgtatatt ttgtaaaaaa acagtagaat agaaaggtat aatttttaaa
    28801 gaaggaataa aaacagtgaa atctattaaa cgttttgcat tctcggctat gggagtggct
    28861 atgttgcttg tcttgactgg ctgtgtcaat gtcgataaaa ccacaggtca gccaacagga
    28921 tttatttgga atacgatcgg agcgcctatg gctgaagcca tcaagtactt cgctactgat
    28981 aaaggtctag gctttggtgt cgctatcatt atcgtaacca ttatcgtacg cttgattatc
    29041 ttaccacttg gtatctacca atcatggaag gcaacgcttc actctgaaaa gatgaacgct
    29101 ctcaagcatg tccttgagcc acaccaaaca cgtctcaaag aagcaactac tcaagaagaa
    29161 aaactcgaag cccaacaagc cctctttgcc gctcaaaaag agcacggcat cagcatgttt
    29221 ggtggtgtag gatgtttccc tatcctcctt caaatgcctt tcttctctgc tatctacttt
    29281 gctgcccaac atactgaagg ggttgctcaa gcaagctacc taggcattcc tctaggttct
    29341 ccaagtatga ttttggttgc ctgtgctggt gtcctttact atcttcaatc gctcctttca
    29401 cttcacggag tagaagatga aatgcaaaga gaacaaatca agaaaatgat ttacatgagc
    29461 ccactcatga tcgtcgtctt ctccctcttc tcaccagcta gtgtcacact ttactgggtt
    29521 gtcggtggtt tcatgatgat tctccaacag tttatcgtca actatatcgt tcgtccaaaa
    29581 cttcgcaaaa aagtccgtga agaactagcc aagaacccac caaaagcaag tgctttctct
    29641 aaaccaagtg gacgaaaaga cgttacccct gaacaaccaa ctgctatcac aagcaagaaa
    29701 aaacacaaaa atcgcaacgc tggaaaacaa cgttcgagat aagaagaaaa aggcttagct
    29761 gatttgctaa gtctttttgc aaatcaaaag cccgatgttt ccatcaggct tcttttctat
    29821 ccatgtacac gtttcatata atcttgataa ctttcggtat ccatgagttt tttagcgttc
    29881 ttgacgcgat ctgctgttgg tggtttgact ccttcgaggg aatatggaat tccaagttca
    29941 cgccacttga actcacccat ggtgtgataa ggtagaattt caaacttatc aacatttttg
    30001 agggtcttga cgaacttacc aagttcaatc aagtcatcat ctctgtctgt caatcctgga
    30061 actagcacgt ggcgaatcca gacaggtttt ccaatatctg atagatactg ggcacaagcc
    30121 aagatatttt tattagtttg gctagtgaca atcttgtgct gttcttcgtt gatttccttg
    30181 atatccaaaa gaaccaagtc agtgacagcc atgagtttgt caaacttctc aaggtaacgt
    30241 ggtttattac ggaaaggaag agcacaggta tccaaggtac agtggattcc ttgttcctta
    30301 gccttggtga agagagcaat caggaaatca atctgcaaga gagcttctcc tccactgact
    30361 gtaatcccac ccttatttcc ccagaaacca cggtagcgca aggcctctgt caagacatca
    30421 tctaccgtcc gttcacgtga cttattggac tccatagccc aagtgtctgg gttgtggcaa
    30481 tactggcaac gcatgtgaca gccctgcaaa aagacaataa agcgaatacc aggcccatct
    30541 actgacccaa agctttctgt cgaatgcacc attcctgtca cttgtccata atcaattgtt
    30601 tcttcagaca tatcgttacc ttccttgaaa acgttttata gttttattat atcacgactt
    30661 gaaggaaaaa caagattttt gcctattttt tagaaagcaa tctgtttttc aatttcattt
    30721 tcaatctatt atcagattat tcttcaaaat cgaagccata taaggttgca aaatagtcct
    30781 cagggcgctc tgcacggcgg atttgacggg ctttaccttc ttcggtatag aggatttccg
    30841 cagaacgtaa tttggcatta tactggtagc ccattgaaaa tccgtgggca cctgtatcat
    30901 gaattaccag caaatcaccg atttctgtat gaggcagttc gcgattgact gcaaatttat
    30961 cattgttttc acagagtgaa ccaaccacat ctaccgcttc agctggtcca tctggatggg
    31021 tcacgttgct aatatgatgg taagctccgt acatagctgg acgtatgagg ttgactgctg
    31081 aggcatccac acctagatag gtacggtagg tttccttctt atgagtcact cttgtgacta
    31141 gagcaccgtg aggtgccagc ataaaacgac ccaattcggt gaaaatcttg acctgaccaa
    31201 gacctgctga cgtaagaact tcttcataca ccttacgaac tccctcacca atcaaggcga
    31261 tatcgttcgg ctcctggtct ggacgataat taacaccaat accgccagaa agattgataa
    31321 agtctagcga aatgcccaac ttttccttga tttcaacagc cagttcaaag agctgacgag
    31381 ccaactctgg ataatagaga tgggtcacgg tattggacgc taggaaggag tgaatcccaa
    31441 aagtcttggc tcctttttcc ttcaagatag caaaggcttc aaagagctgg tccttggtca
    31501 tgccaaactt agcctcccca ggattgtcca taatgtctgt ccccagttca aaaacgcctc
    31561 caggattata acgacaagag atgatttctg gaatgcctgc tactctctcc agatgttcaa
    31621 tatcttcaaa ggcatccaag ttaatggtcg cacccaattc acgtgcatag gcgtattcct
    31681 tgtctggcgt gttgttggaa gagaacataa tctcagaacc cagaaagtcc agtttatggc
    31741 tcatcaaaag ctctacataa ctagagcagt ccacaccaca accttcttct tggagaattt
    31801 tcaaaatagc tggagttgga gtagccttaa ctgcaaaata ttccttaaag cccttgttcc
    31861 acgaaaaagc ttggttgacg gctcttgcct tctcacgaat ccccttctca tcatacaagt
    31921 gaaagggagt cgggaactcg gcaacaatcg cttctaactc ttctctattg ataaatggtg
    31981 ttttcataag cttccttcta ttctgtttgc aaagaaaggc tgggacaatc gttccaacct
    32041 ttagttctat ctcttattta tcttcgtcaa agatattgcc aacctcaaca tcgatggctt
    32101 ggttcttgac atcaatattg gttaccttca agagtgactt gtagtcaaac tgcttttcac
    32161 gttcttcttg ggcattgtcc gcaaagaccg ctacacctgc cagttctgag tcgaactcgc
    32221 gcaagagact aatcatacca ttgaccgttc cgccaccttt caagaagtca tccacaatca
    32281 agacacggct gcctgcctta agactacgtt ttgaaaggaa cattttctcg atacggtcac
    32341 cacttgaacc tgaaacatag ttgacgctaa cagttgaacc ttcggtaatt ttcaggtcac
    32401 ggcgcacaat gacaaaagag acattgagga cattggcaac tgcatttgca agtggcacac
    32461 ccttagttgc tacggtcata accgcgtcaa ttttttggtc cataaagctt ttggcaataa
    32521 tacgaccaat atttttcaag atggctggtg tgctaagcaa atcagacaga tagatataac
    32581 cacctggcaa gatacggtca ctttctgaca acttggtacg caagtcttca accatttcct
    32641 tagcatcctg actcgaaata gacggtgtga agatgacacc tccgccagcc ccagtcactg
    32701 tctggatatg accgatttca atttcctcaa aggcgcgttt gataatgacg atatcttctg
    32761 agatggatga tttagcagac tcatactttt cagcaaaagt attgagacta gttagtttat
    32821 aaggattatt aatcaaatag ttggaaatga caaccatccg atcacttctt cttaatttca
    32881 tttctatttc ctattccatt tttattcaaa aaatcaaaaa gcaaactaga aagctggtcg
    32941 ctggtggttc aaaacactgt tttgagattg tcaatagaac tgacaaaccc tgtaatatac
    33001 ctgcatatat acatacgaca aggcgatact accctagttt gaagagattt tcgaagagta
    33061 ttcatttttg tcttttactt attataccat attcacataa aaaaacgaac attcttatcc
    33121 taaaaaatgc tcatttttct taaattatca atctaaatct ggtttataga aggaacgatt
    33181 atccatagcg aagattttat tggtcatctc tcctttatcc accaaagcca gagctgttga
    33241 catcatcatc atgcttgcat ccagattgtc aatcatatgg ataatctctg cctccataat
    33301 acgtggacgg actggacttc catattcaag caagccgtgg tgactgagga tgacatgacg
    33361 aagcaaaacg acttcttcct tggtatcatc gatgccgagt tccataactg tcttggtaat
    33421 ttcgctatca atgagagcga tatgtccaag aagattacct cgcactgtgt actctgtctg
    33481 gtctggcccc gtcaactcga taaccttagc taagtcatgc agcataatcc ccgcatagag
    33541 caggctctta ttgagctgag gataaacttc gctaatagcg tctgccaaac gtaccatggt
    33601 cgccgtatga taagccaacc ccgtttcaaa ggcatggtgg ttggtcttgg cggctggata
    33661 ggagtagaat tccttatcat acttggtgta gagatttcgg acaatccgtt gccagacagg
    33721 attttcaatt ttgaaaatca tttgcgacat gtagtcacga atttccttga catcaactgg
    33781 tgacttgacc ttgaaatcag ctgggtcatt gggttcacca gcttgaggca ggcggagagt
    33841 aatttgattg acttgagggg tattgttata aacttctcgg cgtcctttca tgtggacaac
    33901 cttacctgcg gtaaaggcct caatgttatg aggttgggca tcccagagct tcccatcaat
    33961 ctcgccacta tcatcttgga aggtaaaggc taggtagttt ttcccagctc gagtttgcct
    34021 caggtcagct gatttgatta ggtaaaagcc ttcaaataac tcatcttttt tcatgtgact
    34081 aatcttcata ttcttcctca ttttcttgaa aatggagtag atcaagcgca ggctcacctt
    34141 ctgacaactc aatgtgacgg agcgtccgct cgatagctat ggtacgacgg tttaataatt
    34201 catcaatatt gccagaggca tgttggagat gtttttgtgc cttgaccaga ataccaccaa
    34261 acttgccaaa ctcggtcttg acactggcaa gagtcttgct gatatggtcg gcactctttt
    34321 ggatattaag ggtcttgaaa ccaactgata gggagttaag aagggctgat agggtacttg
    34381 gtcctgcaac aataatctgt tcttcccgtc tcaaatcatc aaagaagacc ggattgcgga
    34441 cgatttctga gtagagacct tctgtcggaa caaacaaaac tccaaaattg gtcgtccgag
    34501 gtggtgctat gtacttgttc ctaatatccc tagcaaagcg cttgacgctt gctaggagtg
    34561 acttacgaca gcgttcaatc tcatccttgt cacctgtctc ataggcttct tccaagcggt
    34621 aataatctgc cagtggaaac ttagagtcaa ttggcagata aacgtattct tggtcgcctt
    34681 gtccgggtaa cttgatggca tactccactc gttcactaga gttttcaacc gttgcgtatt
    34741 ctcgttcgta ctgggcaggt gtcatgatgt cttcaataat ttgccccagt tgcaattctc
    34801 ccagaatccc tcgcgtcttg gttccagaga gaaccttgtt aagagctccg acatcacggg
    34861 caactgtctg catttctcca aggccacgat tgacagactc cagttgttta gaaactgtct
    34921 caaaggaagc ctgtaagcgt gtctgcaagg tcttttctag tttttcctcg accgtctggc
    34981 gcatttgttc caaacgttgc tcatttgatt cctgcaaggc ttggagacgt tggtctgtct
    35041 tgtctctagt ttggaggaga ttatctgtca tttcttgacg gacttgggtc agaccttggt
    35101 gcaattcaat ccgcacttct tgcaaacggt cgctgacaac cacttccaaa tctttttggt
    35161 ctaactggct ggcttgtctg gcttggtcaa agcggtaatc caactggtct gacaaatgat
    35221 ctgcctgatc ctccaagctc ttacttaagt gtttctcctg cctatcctgt ctttgccaaa
    35281 tcagaaagag accagctagg ttggcaatta ataatagaat aagtaaactt tccatcctac
    35341 ctcctgtcct tgctatgcag tacgaccaca taaccatctg ggcaagtcac cgacacttcc
    35401 ctatctatat attcgttaga agcgtacact tttttaaaga aaaaattctc ctctgtcaac
    35461 tcatacttag ctccaagaat agtcagctgg ctatcccgaa ctggcataaa ggctagatag
    35521 tcgtagtctg aacgaggttc tagctgactg gtcccttctg aacaataggc aatcaaattt
    35581 tgcccatcct caatttctat ttgacgcata tagggtgcca acttaggatt gctaggtaga
    35641 aagacattgg ccaacatatg gtcaatacgg ccacccaagg caccgaaaat agtgacctca
    35701 gcctgaggat tttgttcaaa gatggttaag agagccaatt ccaaatcagt atcatctttt
    35761 tctggccggg cttggacaaa atactgggca cgtttttgaa tcacctgtcg ctcttcttcc
    35821 gtcacagaat caaaatctcc gactgctaga gcaagaggta agtcttcttc caagacccag
    35881 agcgagcctc gatccacccc aacaaaagca tcaaaatctg tccgataatg accgcggttt
    35941 ccgcctgcaa aaactgcaac cctagtccag ttgttttctg agagtttgta ctcgctcatt
    36001 gacttctccc ttaaagacat aggaacctgc tacaaaaaca gtcgcaccag cttctttggc
    36061 ttgagcaata gtttggtcat caatcccacc atccacttcg atttcaaagt tcaaaccttt
    36121 ttcctcacga agagcaacca actcacgaac cttatccatg gtttctggca gaaaggcttg
    36181 cccaccaaaa cctggattaa ccgtcatgac taaaacttgg tcaactagat gaaggacgtg
    36241 cttgatggct tcaactggtg tgccaggatt gataacgact gaaggcttaa ctccgagtga
    36301 acgaattttt tggagggcgc catgaatatg aggtgttgct tctacatgga tactgatgat
    36361 gtctgcacct gcacgcgcaa aatcttccag atgatgctca gggtttgaca ccatcaagtg
    36421 gcaatcgaaa accatcttac tatgaggacg aaggctctcg accacacctg caccaaaact
    36481 gatttgcggt acaaaatgac tgtccatgat atcgatatgg gcatattctg ccccagttgc
    36541 ttctagacgt ttgatttcac gttcaaagtt ggcataatct gctgccagaa ttgacggagc
    36601 aatcttgtat tgagacatag gtttctcctt attttggaat ttttttgctg acttttttat
    36661 aggtttctct acgattttca atttcactaa ggaattgcag gtaattatca aaacggaagg
    36721 ttgcaataac accctcttca acagctggtt tgacggcaca agacggctca tgggtatggg
    36781 tacaagtacg gaacttacaa tctcggctaa cagtagcaat ctctgggaaa gcctgattga
    36841 ggtcttcagc ccttgatact tcatagtcca gagatgaaaa gcctggtgta tctgcgattt
    36901 tacccccgtt gagattgtaa aaactaacag ctcgagtggt atggcgaccg cgacctagac
    36961 tgtctgaaat ttctcccgtt tcaagattga ggtctggtac gagtttattg agaagagttg
    37021 acttcccaac acctgtctgc cccataaaga ccgtaacctt gcctgttaac aaagacagga
    37081 gttcctcttt actggtcaca aagtcatagc cgatgtcacc ataggtctgc cggtaaaaat
    37141 ccagttctcc cctatcttcc aacaaatcca ttttggaaat atagacaatg ggatggatgc
    37201 ccttgtgctc caaaagaacc aagaaacgat ccagcaaatt gctgttaaaa tcaggttcct
    37261 tgacggacat gattactaca gcttgatcga tattgacaat aggcggacga actagactgt
    37321 ttttccgttc gtgaattttt aggatatagc cttctgaatt ttcctcggca gagaaatcta
    37381 cccagtcccc aacataaggg gtatggcctt ttttacggaa attcccacgc gcgcgtgttt
    37441 gataaacctg gccatcactc tccacatagt agaaacctgc caaggcttta atgatttgtc
    37501 cctgcatctt agagtccttg ccctttaagt gcgtctgcta gaccggcaaa ttctgccaag
    37561 ctgagagctt ccccacgcac acttggtgac aagcctgcct ggtccaaagc cttggtcagc
    37621 ttgtccttga cctcttcagt cttaccaaag taacctgtca agttattcca caaggtctta
    37681 cggcgatgga taaaactagc cttggaaacc ttaaagaaga agttctcatc ttccactgct
    37741 acagctggct ctggacggcg caccattttc aagatggctg aatccacatt tggcgctggc
    37801 acaaagaccg tacgaggcac gataaaggca accttggctg tcatgtaata ctgcacggcg
    37861 atagacaagc taccgtaagc cttggtgtta ggctgggctg aaatgcggtc cgctacttct
    37921 ttctgcatca tgaccacaaa ctcactaaaa ggaatgccac tctcaatcaa gtgcatgaga
    37981 ataggcgtcg tgatgtagta aggcaaatta gccactacct tgattggcag gttaggattt
    38041 ttaaaatttt ggatatgttg cgccaaatca accttgagaa tatcttcgtt aactacagtc
    38101 acattatcaa aatcacgcag ggtatctgcc aaaattggca ccaaacggtg gtcaatctca
    38161 aaagccatga cttgggctgc acgctcagcc agaaactccg tcaaggcacc aatacctggc
    38221 ccgatttcga tgacattgac ctggtcatca atttcagccg tatccacaat tttttgaagg
    38281 atattggtat ccgtcaggaa attttgcccg aaggactttt taaaggtaaa accgtgacgc
    38341 tccagcactg ccttggtcac gctataatct gcaattctca tctattctct tttctattat
    38401 ctgttactac tattgtaaca cattcccctt gtattttggg aatgaaaatc ataccaaaaa
    38461 actatctttc ctcatgaaga aagatagtct tggaaatctt taaaagtggc cttaacagtt
    38521 ctctcgaaac atgcgttcaa aaaaatcagc ttcttgataa cttcgatttt cgggtagggt
    38581 caaatccaca tcctcctcca catcatccac tgtcagttca accgtctgag gtaaattttt
    38641 caaacgataa tgcttttgcc tttgcccttc aatactagca aaatcaagca aatagccatg
    38701 cactcggatt tgaaccaaaa ggagatgatt ggtcatattt tccatgatga ggatatcttc
    38761 taaaccacct ctggcactag gataatcaga taccctgcga atacggattt tttcacacat
    38821 gagcaagttt cctcatatca atgatttcat cagccttatt ccagactagg ggattatggg
    38881 tcgcaatgat gataattcga ttttcatctt tcaaatccac caagagattc ataacctcct
    38941 ctgaattttc aggatcaaga gctgctgttg gttcatctgc caaaatcaag ggtggatttt
    39001 tcaaaatagt cttagcaagg gaaactcgtt gggcctctcc cccagataaa gtataaattt
    39061 tttgttctaa atccaaatac cctagattaa ctttttctaa agcccccact tgcctttcca
    39121 aacgttctac ttttgagatt ttctgaccaa caaaacccaa atccaaattt tctttgattg
    39181 attggttttc taagaggcca aaattttgaa agagatagcc catctgatct cgaaaatact
    39241 cacgagtggg aatggttttt aaatctttcc cctgatagag aacccttcct ccatctatct
    39301 tttctagctt tcccaagata ttcagcagcg tcgtctttcc gcttccactc tttccgatta
    39361 aggcataaac cttgcccttc tccagcttga gattcaaacc agagaaaatc gcgcggtcat
    39421 taaatttctt ttccaatcct tgaatatcaa tcatcttatt ttcctttcaa tactgccatg
    39481 ctaccagctt cttctttttt gtcctgcctt actaaaatca agagggcgtt aagcgtaaac
    39541 aaagctacaa ctagagcgct aatcaaacca tctcttgtca aaatactaga taggactagg
    39601 ccaagcaaga gaactcctcc ttgcgccagt aaatacttgc catgaagctc atagattgtc
    39661 ataccagcaa gacgtttaat cataagctcc cgtctgaact gctcaaaata gagaagattc
    39721 atggaatcaa ataacaagat agccgtagac agggtcaaaa tcgtcccaat aaggagagag
    39781 taaaactcca cccgtttgtc atttagtacc ttggcaaaaa atagctggct ttttaccaag
    39841 taagaaacct tgtgatacag accttgctct tttagagctg tgatgctgtc tccatatcga
    39901 tctagtttca aggcactatt agccgtagtt ccccacaaca tccctgcaac aggtcttgtt
    39961 ccagtcgctt gcggcgttag aactacaata atcggatctt ttaggtactg gcgtgttgtc
    40021 ttgtacccat cattatagag gaaacgttcc tgtcctgttt ctgtaaaagc tagccttacc
    40081 tgtgggaggt agtatttctg actcgtcact tctacacttt cagatgaaaa gttttgcagg
    40141 taatctgtaa acaatccttg gtagtaggta gactgctctc gcaagctctc aggcaagatc
    40201 agcccaaact ctccctcaga caagttttgc atcttgtcca taaactctga agaaacggta
    40261 atcttttctt ctatcagata gcgtggtgag acatagataa cattccctga cggtgtgtag
    40321 tcactgagac gattgccatc taggtccact tctgctccat ctgagaaatt gtcaacattg
    40381 ctcataatat aaaaagagtc tgtattggct aaccgttctt cagtaaatgt ctgccactca
    40441 cgattatcct tacgcgttcc ttcttcatcg gcaaatgcac tagaccaacc aaaggataga
    40501 cggtaacggt ctgaggactg gctccattta ttgctagctc tctccatttc ctgcatttca
    40561 cggtagtggg gtaggagagc tgtcgcactc gatccgacca ccaatacagc taagagttgc
    40621 cccaccatca tcaatgtcat catacgtttg agagggagtt tccctttcaa tagatccacc
    40681 agactatttt cctgtaaacc aagtagatag acgacactta gtaaggtaga aatccctgcc
    40741 agggtcaatc cataaagtag aagagcaatg atgaccagtt gcaccgttgc cataaacaag
    40801 gcaccttgat accagagaat ccccaatccc aaaagactgg ataccagcac tgagcagata
    40861 agctgtctca catcttctaa cactggtctg agagcaactc caaacaagct ctcaccagct
    40921 attaagcgaa tccctgcctg acgaagggat ttgatccgat aaatcagggt cagactcata
    40981 aaggtcagca gaaaaatagc taaactcagt agcaccatag gggtggccgt caatagtaag
    41041 actatcgaaa atggatcttc tccattcgaa acaaagcctt gatagccaag ttctttcaag
    41101 gtggtctgta agctcactcc atccaaactt cctgacacaa tcaagtaaga ccctaataaa
    41161 tcactcgttt ctgcactctc cttggaggaa atggtcagac cttctggaag ctctccctca
    41221 ccataagtgg cataggtaaa gagtgtttct ccagcttcat ttggctcaac gattcgacgg
    41281 gcgatgagac tattatgctc taccgccaag tgactcaaag cctctgtcac ctcttcgcga
    41341 ctagctactg gttgatttat catcattcct gtcacatcaa cagaaggata gttaccaaat
    41401 aaaatctctt ctcgatggtc aacggaagtt atcaccatat aaagcgatac caataccatt
    41461 gaaatcaaaa taaataaacg tttcatcatt tcctccaaaa agttacttgg tcacttagtg
    41521 agaaggtgac cacagtcact gcgatgttaa gaagcttatt aagttctttc tgctagcaac
    41581 atcttcaaat atattatatc cgttttttca agaactatca aggacatcaa tgtccttaaa
    41641 atctaactat ttcatattat ttttagctta tatctaaaaa aacagttcta aagacgaact
    41701 ttagaactgt tttgatacga ggacaaggac atttttgtca ctgattcact atgtttataa
    41761 atattttttg acatcctctt gccattcctc tgtcaatttc tttactagaa atccatctcc
    41821 aattagcttc gcaaatgttt tagaagactg ataaaatgat tcagctaaac taaaatctct
    41881 ttctactctt aatgcttgct tccacaaaaa cataaataca agaggtttct tttgataacc
    41941 ttgagtttta tccataattt cttgtaaaca cgatagataa tcattaaaac aatcagttac
    42001 tcctaccttt tcaagacaac acattcctga aataagagta tctctaatta taaagtaatt
    42061 ctctatttga gttaccttct tctgttccaa aagaaagagc attagctttt cgatttgatt
    42121 tataaatttg gcaagatctt ttctaatgag catttgataa aaaaacaaac gaatcaacaa
    42181 catatcattt gttgaataaa cttctttttc tatgatctga ggcatatgtt cctcaagtat
    42241 taactctgca tattcaggcc ttctagttct agaagtatcc aaacacgcct gcaatacttc
    42301 acatgctaat tgttcttctt taggaagatt atcaaagtat gttttataaa tctcttccaa
    42361 acacgcttct ttcttatcat actcctcttc tttaccatag attggttcac gtaaaatctg
    42421 gtatttcaat tctaaataag caggaggaag agctgaaaaa tccggcataa ggctataaac
    42481 tggaactcct agccggtgag caatatagtc taacttgggc aaactcggtt gcgaagctcc
    42541 actttcaatt cgcgacagtt gacgaactgt cagttcttgc tcatctccac aaaaatctgg
    42601 acgactaatt cctttttcta tccgaatctc tttaattttt tgaccaatta acatcagacg
    42661 cctcctcttc tacctgcttc gaaaaatact gtgaaactta aaaaattgta acggtcacat
    42721 ctttcctact cataagattt catagcttct tccacttctg ccaaagtaac cccaaacaac
    42781 tctaggcgtt tgaggagttg cttgccgtta gaatagccga ttcggagagt ctctccgaga
    42841 tattccctac gcttacggct gtctgcccct actagaaaac caaggcgaat caagtcgcta
    42901 cgactaatgt caaactgact ctcatgttca aattgttctg tcacctgagc tagagccgtt
    42961 ttcaggtctt catagctggc atgctcaatt cccagagaac gccccttggt cttggacttg
    43021 ggaacagctt catctcgctt gagaaaggca tgctgaactg ttggaatggc cgtcataatc
    43081 atgcgccgaa tccgctcccc attaaaatct gggtctgtaa agacaatgac tccatgacgt
    43141 tggtgtagac gctgaatccg ctctatgtcc tggtcattga tggcagaacc tcgagtctca
    43201 taggtctcca catcgaaata acgcttgaga ttgaccgtat catcgcgacc ttcaaccacg
    43261 ataacttggg aaattttctc tttcattact tgctgtccaa tccaaaaatg cgttctgcat
    43321 ttgcagtcgt tgccgccgct agctcttctg tcgtcatacc acgcaagtca gcgataaagt
    43381 ccaccacata gcgagtatag gctgttttat tttcacggcc acgcttgggt acaggtgcta
    43441 agtaaggcgc atctgtttcc accaacatct tgtccaaagg taactcttta gctgcttctt
    43501 ggaggtcagt tgccttcttg aaagtcacca ctcctgagaa ggaaatggtc ataccaagat
    43561 ccacaaactt ctctgcccac tcaagcgtcc ctgaaaatga atgcatgata ccaccacgag
    43621 gaccaacgcc ctcactcttg ataatctcat aggtatcttc cagcgcatca cgggtatgga
    43681 caacaaaagg caaatccaag ttcttagata gctgaatctg acggcgaaaa acctgctcct
    43741 gcacctcttt gggcgctgtc atccaatggt agtctaagcc aatttcacct aaagccacaa
    43801 ccttggaatg ttttaactta tccaacaagt aagcctcaac ttcctctgta taagtaccag
    43861 cttctgtagg atgccaacca atagtcgcat agagctgctc atactcatct accaactcca
    43921 aggcatgctc aatcgtcggt ttatcaaaac caacaatatt catctgtgtc acacccatct
    43981 catcagccaa ggcaatttct tctgcctcac gacctgcaaa ttcttctaca ttcaagtgtg
    44041 tatgtgtatc aaaaatcatc tcttctaacc tcgttttcta tcttctatta taccaaaaaa
    44101 gaggaggggc acctaatttt tcggtttccc ctcctctctt caatagggag ctattctgct
    44161 atcttttcta tccgatattg cccatctcct attccacagt tagagacaga agagattggc
    44221 tacattgata gaatattcct attcagctaa agtatgtgat tatcttgggt tctcactttt
    44281 ctcacccatc actaggattg atgacttctc aaaatccctc ttataatcta actttaagta
    44341 gagaatagaa ttttctagct gttctatttt ctacgtctag tctttcttcc tagcaaagca
    44401 aaaccacttg ttgccaccac tagaccaaga ctagcaagtg ctgcacttga tgctgaaccc
    44461 gtgttaggta attgtttgcc agcaggtgac tggtaggtaa catcttgcat tgttcctgca
    44521 gttgcttgcg gtgcacttgt tgtcttagga gcagtattag gagccactgg tctcttagga
    44581 actgtaacca tgacaatggc ttgcactcca atcgtttctg cttccttcac atcttccata
    44641 gttttcgcat tttcaatctc tttgagagct gcttgttttt ctgcttccac tcttgctaaa
    44701 agttctgctt tttctttatc agaaagcggt gcgcctttga tttcatcctg cttgtccttg
    44761 gctgcttttt caatggcatt tttagctgat tctttttcag tagctaattg cttagaagct
    44821 tgtgattgag ctgagttttg tgaacctgtg tgagctgatc cacccgcctg gctaccaccg
    44881 ccttcattcg cattagcatc tgagcttcca gtattgcctc ccttatctcc acctggtgta
    44941 gtttctagct tatactctgg tgtagcttct tgagttacag attcaccttt cgcagattgt
    45001 tgaactgtat cttttcctag aatcgtcact actgaaccat ctgggaatgt gattgttgct
    45061 gtaccatatc cagctacatt gattgtcgct ccgtctaatg ctgaaccatt tgcttgtaaa
    45121 atagcaacct taactttttc tttttcttca tctgttaaat gagttatatc ttttacatct
    45181 actctttgag caggtgcttt aacagttgat ttttcagcag tcggtttagt gctatcttgt
    45241 gcttttggat cttgtgctac caattgattt cctggaattg taatagctga accatcttta
    45301 aagacgattg ttgctgtacc atatccacct acttcaactt tatagtaaaa taaaataata
    45361 acaggacaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag aaacagaggt
    45421 gtactattct agtttcaatc tactgtaaca tcgcttccga atccatttgc atctactgaa
    45481 cttttttaca aaaataaaaa tcagtagact cgagttccta ctgatttttg atagaattcg
    45541 tttggattat gcagccaaaa ctttgcgtcc tttacgacga cgagctgcca atacgcgacg
    45601 accattttta gttgacatac ggttacggaa tccgtgtttg cgcgcacgac gaagtttact
    45661 tggttgataa gtacgtttca cgatgaatac ctcctcatag attttgtatt cgtttagccg
    45721 gctataaagt gatcagttac taaacatact ttactattct atctgattct ttcacttttg
    45781 tcaatagctc taggcaaatg tttccagctt tttcgaatgc aagccc
//
LOCUS       DAVKAU010000014        44570 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVKAU010000014 DAVKAU010000000
VERSION     DAVKAU010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44570
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.014"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(66..254)
                     /locus_tag="VWX48_000866"
     CDS             complement(66..254)
                     /locus_tag="VWX48_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU9171517.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(370..855)
                     /locus_tag="VWX48_000867"
     CDS             complement(370..855)
                     /locus_tag="VWX48_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU9171518.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(1283..2827)
                     /locus_tag="VWX48_000868"
     CDS             complement(1283..2827)
                     /locus_tag="VWX48_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU9171519.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            3040..3342
                     /gene="gatC"
                     /locus_tag="VWX48_000869"
     CDS             3040..3342
                     /gene="gatC"
                     /locus_tag="VWX48_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU9171520.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            3342..4808
                     /gene="gatA"
                     /locus_tag="VWX48_000870"
     CDS             3342..4808
                     /gene="gatA"
                     /locus_tag="VWX48_000870"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU9171521.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMNEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            4808..6250
                     /gene="gatB"
                     /locus_tag="VWX48_000871"
     CDS             4808..6250
                     /gene="gatB"
                     /locus_tag="VWX48_000871"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU9171522.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            6379..6939
                     /gene="efp"
                     /locus_tag="VWX48_000872"
     CDS             6379..6939
                     /gene="efp"
                     /locus_tag="VWX48_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU9171523.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            6961..7350
                     /locus_tag="VWX48_000873"
     CDS             6961..7350
                     /locus_tag="VWX48_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9171524.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            7343..7765
                     /gene="nusB"
                     /locus_tag="VWX48_000874"
     CDS             7343..7765
                     /gene="nusB"
                     /locus_tag="VWX48_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU9171525.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(7814..8422)
                     /locus_tag="VWX48_000875"
                     /pseudo
     CDS             complement(7814..8422)
                     /locus_tag="VWX48_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520572.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(8440..8625)
                     /gene="briC"
                     /locus_tag="VWX48_000876"
     CDS             complement(8440..8625)
                     /gene="briC"
                     /locus_tag="VWX48_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU9171526.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(8784..9551)
                     /locus_tag="VWX48_000877"
     CDS             complement(8784..9551)
                     /locus_tag="VWX48_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU9171527.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(9548..10414)
                     /locus_tag="VWX48_000878"
     CDS             complement(9548..10414)
                     /locus_tag="VWX48_000878"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU9171528.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(10451..11818)
                     /gene="accC"
                     /locus_tag="VWX48_000879"
     CDS             complement(10451..11818)
                     /gene="accC"
                     /locus_tag="VWX48_000879"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU9171529.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(11830..12252)
                     /gene="fabZ"
                     /locus_tag="VWX48_000880"
     CDS             complement(11830..12252)
                     /gene="fabZ"
                     /locus_tag="VWX48_000880"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU9171530.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(12249..12734)
                     /locus_tag="VWX48_000881"
     CDS             complement(12249..12734)
                     /locus_tag="VWX48_000881"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU9171531.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(12737..13972)
                     /gene="fabF"
                     /locus_tag="VWX48_000882"
     CDS             complement(12737..13972)
                     /gene="fabF"
                     /locus_tag="VWX48_000882"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU9171532.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     AFGFGGHNAVLAFKRWENR"
     gene            complement(13994..14725)
                     /gene="fabG"
                     /locus_tag="VWX48_000883"
     CDS             complement(13994..14725)
                     /gene="fabG"
                     /locus_tag="VWX48_000883"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU9171533.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(14759..15679)
                     /gene="fabD"
                     /locus_tag="VWX48_000884"
     CDS             complement(14759..15679)
                     /gene="fabD"
                     /locus_tag="VWX48_000884"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU9171534.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(15672..16646)
                     /gene="fabK"
                     /locus_tag="VWX48_000885"
     CDS             complement(15672..16646)
                     /gene="fabK"
                     /locus_tag="VWX48_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU9171535.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(16765..16989)
                     /locus_tag="VWX48_000886"
     CDS             complement(16765..16989)
                     /locus_tag="VWX48_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9171536.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(17048..18022)
                     /locus_tag="VWX48_000887"
     CDS             complement(17048..18022)
                     /locus_tag="VWX48_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU9171537.1"
                     /translation="MAFAKISQVSHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(18022..18456)
                     /locus_tag="VWX48_000888"
     CDS             complement(18022..18456)
                     /locus_tag="VWX48_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9171538.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(18550..19335)
                     /locus_tag="VWX48_000889"
     CDS             complement(18550..19335)
                     /locus_tag="VWX48_000889"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU9171539.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            19660..21024
                     /locus_tag="VWX48_000890"
     CDS             19660..21024
                     /locus_tag="VWX48_000890"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU9171540.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRELTPIKEEEILRQLVQKTKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGK
                     SKED"
     gene            21027..21398
                     /locus_tag="VWX48_000891"
     CDS             21027..21398
                     /locus_tag="VWX48_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU9171541.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            21612..22886
                     /gene="serS"
                     /locus_tag="VWX48_000892"
     CDS             21612..22886
                     /gene="serS"
                     /locus_tag="VWX48_000892"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU9171542.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(22911..23810)
                     /locus_tag="VWX48_000893"
     CDS             complement(22911..23810)
                     /locus_tag="VWX48_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU9171543.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(23920..24468)
                     /locus_tag="VWX48_000894"
     CDS             complement(23920..24468)
                     /locus_tag="VWX48_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU9171544.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(24686..26008)
                     /locus_tag="VWX48_000895"
     CDS             complement(24686..26008)
                     /locus_tag="VWX48_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU9171545.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFTALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(26099..26187)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(26351..28687)
                     /locus_tag="VWX48_000896"
     CDS             complement(26351..28687)
                     /locus_tag="VWX48_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU9171546.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRVLKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(28791..29339)
                     /locus_tag="VWX48_000897"
     CDS             complement(28791..29339)
                     /locus_tag="VWX48_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU9171547.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(29336..29638)
                     /gene="zapA"
                     /locus_tag="VWX48_000898"
     CDS             complement(29336..29638)
                     /gene="zapA"
                     /locus_tag="VWX48_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU9171548.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            29725..30606
                     /locus_tag="VWX48_000899"
     CDS             29725..30606
                     /locus_tag="VWX48_000899"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU9171549.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            30610..31224
                     /gene="lepB"
                     /locus_tag="VWX48_000900"
     CDS             30610..31224
                     /gene="lepB"
                     /locus_tag="VWX48_000900"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU9171550.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            31351..33717
                     /locus_tag="VWX48_000901"
     CDS             31351..33717
                     /locus_tag="VWX48_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU9171551.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMILAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQTCMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(33765..35048)
                     /locus_tag="VWX48_000902"
     CDS             complement(33765..35048)
                     /locus_tag="VWX48_000902"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU9171552.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(35242..35601)
                     /locus_tag="VWX48_000903"
     CDS             complement(35242..35601)
                     /locus_tag="VWX48_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9171553.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPIIAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(35900..36814)
                     /locus_tag="VWX48_000904"
     CDS             complement(35900..36814)
                     /locus_tag="VWX48_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU9171554.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LQDSPGTNNFSLPNVSPTYGQYYTNQSEVIIGKNDLVKVKNTLQYPYSTSAYVESEFR
                     GVKNGKDVTYRGSANFIKDNVLITAAHNIYKHEFGKDAEELYVTPARTPNSVPFGRIK
                     VKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLTGITVTITGY
                     PSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASNRVVGVHTLGDGAN
                     QINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(36964..37230)
                     /locus_tag="VWX48_000905"
                     /pseudo
     CDS             complement(36964..37230)
                     /locus_tag="VWX48_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(37255..37566)
                     /locus_tag="VWX48_000906"
     CDS             complement(37255..37566)
                     /locus_tag="VWX48_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9171555.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(37491..37733)
                     /locus_tag="VWX48_000907"
     CDS             complement(37491..37733)
                     /locus_tag="VWX48_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9171556.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(37734..38366)
                     /locus_tag="VWX48_000908"
     CDS             complement(37734..38366)
                     /locus_tag="VWX48_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9171557.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQATVYAFQHHLVGQEEF"
     gene            complement(38380..39375)
                     /locus_tag="VWX48_000909"
     CDS             complement(38380..39375)
                     /locus_tag="VWX48_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9171558.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(39372..40070)
                     /locus_tag="VWX48_000910"
     CDS             complement(39372..40070)
                     /locus_tag="VWX48_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU9171559.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(40148..41158)
                     /locus_tag="VWX48_000911"
     CDS             complement(40148..41158)
                     /locus_tag="VWX48_000911"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU9171560.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYIKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(41142..42149)
                     /locus_tag="VWX48_000912"
     CDS             complement(41142..42149)
                     /locus_tag="VWX48_000912"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU9171561.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(42136..43089)
                     /gene="mvaD"
                     /locus_tag="VWX48_000913"
     CDS             complement(42136..43089)
                     /gene="mvaD"
                     /locus_tag="VWX48_000913"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU9171562.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(43071..43949)
                     /gene="mvk"
                     /locus_tag="VWX48_000914"
     CDS             complement(43071..43949)
                     /gene="mvk"
                     /locus_tag="VWX48_000914"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU9171563.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVS
                     AESPWRLYEEDTLSMAVYASLEYLDITEACVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETALSYGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(44071..44400)
                     /locus_tag="VWX48_000915"
     CDS             complement(44071..44400)
                     /locus_tag="VWX48_000915"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9171564.1"
                     /translation="MTRKVYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYFVN
                     YNGEWVQ"
BASE COUNT        13028 a        10264 c         8477 g        12801 t
ORIGIN      
        1 ttttcaaacg atgttatacc cacaataaaa gaaaaaagac cctaaggtct cctttgcttt
       61 tattattaaa cgcgttcaac tttacctgat ttcaaagcac gagctgaagc ccaaactttt
      121 ttaggtttac catcgataag aacagtaact ttttgaaggt ttggttttac ggcacgtttt
      181 gtttggttca tcgcgtgtga acggttgttt cctgatacag tcttacgacc tgtaaagtaa
      241 catactttag ccattgtgtt ttcctcctat tagatctaat atagcggatg tgctagcacc
      301 acataccgta ctatgttatc acactttctt gttttttgca agggaattgg aagatttttt
      361 atttgtgtct taaatcaggt cttgcgtgac attttctgct ctccacatgc cattgttgat
      421 taacagaaca ccagaattaa aattatgtgt ataaaaatca tctctaactg cagctaaggg
      481 tatagccgtc aagtccaaat cccacagctc atctatcgat tttcttacaa caatatctga
      541 atccaaatac agtacacgag actcgcttac atactttgga ataaaatacc taaaaaaagc
      601 cgcatatgaa agtccctcaa aggggagacg ataacctttc agaatactac tgtcaatctg
      661 aacattcaca atctcactat tcaaagtctc tagtcttttt tccatcaatt ggaaccattc
      721 tcgcggaagg tcatcattaa aaacataaaa cttaagatta taatgatgaa cacaaagaga
      781 ttttattgtt gtttcaactt tatccatata agcattatct gcacctaaga caatcgcttt
      841 tttctcttct ttcactcttt atctcatttc tttttattcc catcatatgt ttctacgtaa
      901 ccattatttt cgcccattcg ttcgtaaaac cataccagtg gagattttag atgaagtccc
      961 attacggttt acaattttta cattacgaca cggagtttta caaatcgatt tcatttgcca
     1021 aacgtagtta gtaaggcaat tagctaggct acctactttc tgctacgacg gaaaaatcca
     1081 caaatcaata ccattcgtgg atttttccta gtgaagcgtt taggtaagcc gccatagcgg
     1141 ttaccgatta ttagattacg acacggagtt tggcaaatcg attctatttg ccaaacgtag
     1201 ttagtgaggc agttagctag ttcgccaaat agcgactagc gtccaacaat ttggaacttt
     1261 agttccaatt gttggtactg agtcacatct tctcctctaa ctctacgtct ggatacttgt
     1321 ccgcaaacca gcggagggca aagtcatttt caaagagaaa gactggttgg tcaaaacggt
     1381 ctttggctaa gatattgcga cttgacgaca tccgttcatc caagtcctca ggcttgatcc
     1441 aacgaacggt ctttttaccc attggggtca taactacttc cgcattgtac tcgccttcca
     1501 tgcggtgttt aaagacttca aactggagtt gacctacagc gcctagcatg tactcacctg
     1561 tttggtaatt cttataaagc tgaacggctc cttcttgcac caattgctca atccccttgt
     1621 ggaaggattt ttgcttcata acattcttag cagaaacttt catgaaaatt tcaggagtaa
     1681 aggttggcag gggttcaaat tcaaacttgt tttttccaac cgtcaaggta tccccaacct
     1741 gataagtacc ggtatcgtaa accccgataa tatcacctgc cacggcattg gtcacattct
     1801 cacgactctc cgccataaac tgggtaacat tagatagttt ggccccctta ccagtacgag
     1861 gaagattgac actcatgcca cgctcaaatt cgcctgatac gatacgaaca aaggcaatac
     1921 ggtcacggtg acgaggatcc atgttggctt ggattttaaa gacaaagcct gagaaatcct
     1981 tgtcataagg atccacaatt tcaccgtctg ttttcttgtg accatgtggt tctggagcaa
     2041 acttgaggaa gatttcaagg aaggtctgca caccaaagtt tgtcagggct gaaccgaaaa
     2101 agacaggcgt caattctcca gccagaatag cttcctctga aaactcattc ccagcttcat
     2161 ttaaaagctc aatgtcatcc ttgacttgct cgtagaaagg attgctacca aaaagtttgt
     2221 ctccatcttc taggctagca aaacgctcat cccctttata aagttctaaa cgttggttat
     2281 agaggtcata caagccctca aaggctttcc ccatcccgat aggccagttc atagggtagc
     2341 tagcaatgcc caagatttct tccaattctt gcaagagttc caaaggctca cgaccgtcac
     2401 ggtccagctt gttcataaag gtaaagactg gaatgccacg atgtttcaca acctcaaaca
     2461 atttcttggt ttgagcctcg atccccttgg cagagtccac gaccatgacc gcagcatcca
     2521 ccgccatcaa ggtacgatag gtatcttctg agaagtcctc gtgccctggc gtgtctaaga
     2581 tattcacgcg cttgccgtcg tagtcaaatt gcataacaga tgaagtaaca gaaatcccac
     2641 gttgcttctc gatatccatc cagtcagatt tagcaaaagt ccctgttttc ttccctttta
     2701 ccgtaccagc ctcacgaatc tcacccccaa agtagagtaa ctgctcagtg atggttgttt
     2761 tccccgcgtc cgggtgggag ataatggcaa aggtacgacg tttcttaatt tcttcttgaa
     2821 tattcataag ttctctttct ttgattctct atttttcttg tttcaatagc tgagaatgat
     2881 ttttacattg gattttacca ttcctttcaa cactccatta tatcggattt tagcattttt
     2941 ttcaatttct atttcttttc acttccccct cccttattta taggaaaata tggtaaaata
     3001 gaacagacta aaaatcatca tttcacgaaa ggatgcaaga tgaaaattac gcaagaagag
     3061 gtaacacacg ttgccaatct ttcaaaatta agattctctg aagaagaaac tgctgccttt
     3121 gcgaccacct tgtctaagat tgttgacatg gttgaattgc tgggcgaagt tgacacaact
     3181 ggtgtcgcac ctactacgac tatggctgac cgcaagactg tactccgccc tgatgtggcc
     3241 gaagaaggaa tagaccgtga tcgcttgttt aaaaacgtac ctgaaaaaga caactactat
     3301 atcaaggtgc cagctatcct agacgatgga ggagatgcct aatgactttt aacaataaaa
     3361 ctattgaaga gttgcacaat ctccttgtct ctaaggaaat ttctgcaaca gaattgaccc
     3421 aagcaacact tgaaaatatc aagtctcgtg aggaagccct caattcattt gtcaccatcg
     3481 ctgaggagca agctcttgtt caagctaaag ccattgatga agctggaatt gatgctgaca
     3541 atgtcctttc aggaattcca cttgctgtta aggataacat ctctacagac ggtattctca
     3601 caactgctgc ctcaaaaatg ctctacaact atgagccaat ctttgatgcg acagctgttg
     3661 ccaatgcaaa aaccaagggc atgattgtcg ttggaaagac caacatgaac gaatttgcta
     3721 tgggtggttc cggtgaaact tcacactacg gagcaactaa aaacgcttgg gaccacagca
     3781 aggttcctgg tgggtcatca agtggttctg ccgcagctgt agcctcagga caagttcgct
     3841 tgtcacttgg ttctgatact ggtggttcca tccgccaacc tgctgccttc aacggaatcg
     3901 ttggtctcaa accaacctac ggaacagttt cacgtttcgg tctcattgcc tttggtagct
     3961 cattagacca gattggacct tttgctccta ctgttaagga aaatgccctc ttgctcaacg
     4021 ctattgccag cgaagatgct aaagactcta cttctgctcc tgtccgcatc gccgacttta
     4081 cttcaaaaat cggccaagac attaagggca tgaaaattgc tttgcctaag gaatacctag
     4141 gcgaaggaat tgatccagag gttaaggaaa caatcttaaa cgcggccaaa cactttgaaa
     4201 aattgggtgc tatcgtcgaa gaagtcagcc ttcctcactc taaatacggt gttgccgttt
     4261 attacatcat cgcttcatca gaagcttcat caaacttgca acgttttgac ggtatccgtt
     4321 acggctaccg cgcagaagat gcgactaatc ttgatgaaat ctatgtaaac agccgtagcc
     4381 aaggttttgg tgaagaagtg aagcgccgta tcatgctggg tactttcagt ctttcatcag
     4441 gttactacga tgcctactac aagaaggctg gacaggtccg tacacttatc attcaagatt
     4501 tcgaaaaagt cttcgcggat tacgatttga ttttgggtcc aactgctcca agtgttgcct
     4561 atgacttgga ttctctcaac catgacccag ttgccatgta cttagccgac ctcttgacca
     4621 tacctgtaaa cttggcagga ctgcctggaa tttcgattcc tgctggattc tctcaaggtc
     4681 tacctgtcgg actccaattg attggtccca agtactctga ggaaaccatt taccaagctg
     4741 ctgctgcttt tgaagcaaca acagactacc acaaacaaca acccgtgatt tttggaggtg
     4801 acaactaatg aactttgaaa cagtcatcgg acttgaagtc cacgtagagc tcaacaccaa
     4861 ttcaaaaatc ttctcaccta cttctgccca ctttggaaat gaccaaaatg ccaacactaa
     4921 cgtgattgac tggtctttcc caggagttct accagttctc aataaagggg ttgttgatgc
     4981 cggtatcaag gctgctcttg ccctcaacat ggacctccac aaaaaaatgc actttgaccg
     5041 caagaactac ttctaccctg ataatcccaa agcctaccaa atttctcagt ttgatgagcc
     5101 aatcggttat aacggctgga ttgaagtcga gctagaagac ggtacgacca agaaaattgg
     5161 tatcgaacgc gcccacttag aggaagacgc tggtaaaaac acccacggta cagacggcta
     5221 ctcttacgtt gaccttaacc gccaaggggt acctttgatt gagattgtat ctgaagccga
     5281 tatgcgttcg ccagaggagg cctatgctta tctgacagcc ctcaaggaag ttatccagta
     5341 cgctggcatt tctgacgtta agatggaaga aggttctatg cgtgtggatg ccaacatctc
     5401 ccttcgccct tatggtcaag aaaaattcgg taccaagact gaattgaaga acctcaactc
     5461 cttctcaaac gttcgtaaag gtcttgaata cgaagtccaa cgccaggctg aaattcttcg
     5521 ctcaggtggt caaatccgcc aagaaacacg ccgttacgat gaagctaaca aaacaaccat
     5581 cctcatgcgt gtcaaggaag gggctgctga ctaccgctac ttcccagaac cagacctacc
     5641 cctctttgaa atttctgacg agtggattga ggaaatgagg actgagttgc cagagtttcc
     5701 aaaagaacgt cgtgcgcgtt atgtatctga ccttggttta tcagactacg atgctagtca
     5761 gttgactgct aataaagtca cttctgactt ctttgaaaaa gctgttgccc taggtggtga
     5821 tgccaaacaa gtctctaact ggctccaagg ggaagtcgct cagttcttga atgctgaagg
     5881 taaaacactg gaacaaatcg aattgacacc agaaaacttg gttgaaatga ttaccatcat
     5941 cgaagacggt actatttcat ctaagattgc caagaaagtc tttgtccatc tagctaaaaa
     6001 tggcggtggc gcgcgtgaat acgtggaaaa agcaggtatg gttcaaattt cagatccagc
     6061 tgttttgatt ccaatcatcc accaagtctt tgccgataac gaagctgctg ttgccgactt
     6121 caagtcaggc aaacgtaacg ccgacaaggc ctttacagga ttccttatga aggcaaccaa
     6181 aggccaagcc aacccacaag ttgcccttaa actacttgca caggaattgg cgaagttgaa
     6241 agaaaactag atagaacaaa accagcccta aggttggttt tttcttctct accaactccc
     6301 aataactatt ttggctttat ttccagagta ttttatggta aaatgaagag taataatatt
     6361 tattaaagag gtaaaaacat gattgaagca agtaaattaa aagctggtat gacctttgaa
     6421 acagctgacg gcaaattgat tcgcgttttg gaagctagtc accacaaacc aggtaaagga
     6481 aacacgatca tgcgtatgaa attacgtgat gtccgtactg gttctacatt tgacacaagc
     6541 taccgtccag aggaaaaatt tgaacaagct attatcgaga ctgtcccagc tcaatacttg
     6601 tacaaaatgg atgacacagc atacttcatg aatacagaaa cttacgacca gtacgaaatc
     6661 cctgtagtca atgttgaaaa cgaattgctt tacatccttg aaaactctga tgtgaaaatc
     6721 caattctacg gaactgaagt gatcggtgtc accgttccta ctactgttga gttgacagtt
     6781 gctgaaactc aaccatctat caaaggtgct actgttacag gttctggcaa accagcaacg
     6841 atggaaactg gacttgtcgt aaacgttcca gacttcatcg aagcaggaca aaaactcgtt
     6901 atcaacactg cagaaggaac ttacgtttct cgtgcctaat ctctagaaag aggtcattct
     6961 atgggaattg aagaacaact tggcgaaatc gttatcgccc cacgtgtact tgaaaaaatc
     7021 attgctattg ctactgcaaa ggtagagggt gttcactctt tttcaaacag atcagtgtct
     7081 gatacccttt caaaactttc actcggccgt ggcatttatc ttaaaaacgt ggacgaagaa
     7141 ctcacagcag atatctatct ctaccttgag tacggagtaa aagttcctaa ggtagcggtt
     7201 gctatccaga aagctgtcaa agatgccgtc cgtaatatgg ctgatgtaga actcgctgct
     7261 atcaatattc acgttgcagg tatcgtccca gataaaacac caaaaccaga attgaaagat
     7321 ctatttgacg aggacttcct caatgactag tccactatta gaatctagac gccaactccg
     7381 taaatgcgct tttcaagctc tcatgagcct tgagttcggt acggatgtcg aaactgcttg
     7441 tcgtttcgcc tatactcatg atcgtgaaga tacggatgta caacttccag cctttttgat
     7501 agacctcgtt tctggtgttc aagctaaaaa ggaagaacta gataagcaaa tcactcagca
     7561 tttaaaagca ggttggacca ttgaacgctt aacgctcgtg gagagaaacc tccttcgctt
     7621 gggagtcttt gaaatcactt catttgacac tcctcagctg gttgctgtta atgaagctat
     7681 cgagcttgca aaggacttct ccgatcaaaa atctgcccgt tttatcaatg gactgctcag
     7741 ccagtttgta acagaagaac aataaaaaga aaaagtgttt gatatctatc aaacactttt
     7801 tctttgcctc ccactatcta aaaaaatgat aatagatata attgtaaaca aaaatccaga
     7861 taggttttgc atgattgaga aagttaaaaa aactatggca gagaatcgtt aatctcagat
     7921 tgtcggtaga acgataaaca agggcaaaaa agaaaccaat cagactataa tataataaac
     7981 taattggatc tctgtgagat agtatcaaat ggctaatccc aaagataagg cctgataaga
     8041 tgacatctaa atagtacttt gacttaggaa agaaggtatt cataaaatac cctctatcaa
     8101 gagtctcctc aaaaaaatga gcatagcgtg cctaaaaatt accgagaatc tgataaacca
     8161 cataagttgc aaataagtag aagacaaatg accagttcca gctctttttt tcaaagataa
     8221 agagcatctt tttctttttt aacctccaaa ttaatagaag gaaacttccc actaatacca
     8281 ttgttaaaat aagagaatag acatcagctc ctaaccctaa aatgatcgtc acatacaatc
     8341 caattgtttg tggtaaatag gtagatagta aaataataag caaaaatatt ccaaattgtc
     8401 ttagtttctt tgtgtttctc atcgtacttt tttgaaagat taccctgctc ggaagccgta
     8461 cttccaagca tctatataag aattaagtgc cccttgcctc atatagggag caaattctct
     8521 ataatataac catctactat atccatcttc ccaaacagca agaccacctg aagtttgctc
     8581 caagtcctca gttgaaagaa ctgtaaatgt atttgtacct gtcattgcaa gtaccttctt
     8641 aaaatagatt gttgtaggct cacatttata gtatatttct ttttttgtct attttatagc
     8701 tcatctcctc aactggcaat ttttcgacct gaattgcatt tttccataaa aaatgagacc
     8761 tttctagtct catttagtca ttcttagtat tttctaaatc gttgatagcg ttcttccagc
     8821 aactcttcta gcggtttttg tgaaagtcta gccagctccg tttggagttc ttttttgaca
     8881 ctcttaatca gttctttact agaaagtcct acttcagaaa tcaccttatc caccacgtcc
     8941 atttctaaca gttcatgcga agtgattttc atcagttctg ctgcttccat ggcgcgagta
     9001 ccgtccttcc ataaaatgga agcaaagcct tctggactga gaatggcata gatagaattt
     9061 tccagcatcc agacacggtc cgcgacagct agagccagag ccccgcctga accaccttca
     9121 ccgataataa tggcgataat aggaactttc aggtcactca tttccatgag attgcgagcg
     9181 atagcttccc cttgaccacg ttcttccgct ccgacaccag gataagcacc tgctgtattg
     9241 ataaaggtca caactggacg gccaaatttc tcagcctgtt tcatcaaccg cagtgccttt
     9301 cggtagcctt ctggatgtgg ttggccaaaa ttccgtttga ggttgtcttg caaactcttg
     9361 cctttttgga taccaaccac tgttacagct tggtctccaa gccaaccaat accaccaaca
     9421 actgcaccat catcacgaaa agaacggtca ccatgtaatt ggataaattc atcaaaaatg
     9481 cctgtcgcaa agtccaaggt tgtcaagcga ctctgctcac gcgcttctct gactattttt
     9541 gcaatattca tctaggactc cctccatgca atctgactag gctagcaatc gtatctggta
     9601 agtctcttct tttgacaata gcatccacaa agccatgttc taataggaat tctgcctttt
     9661 ggaaatcctc aggcaagctt tcacgaaccg tattttcaat cacacgacgc ccagcaaaac
     9721 caaccaagct ctgtggttca gccagaatga tatcgccttc catagcgaaa gaagctgtca
     9781 caccaccagt cgttggatct gtcaaaatgg tcaggtaaaa gagaccagca tttgaatggc
     9841 gtttaaccgc cgcagagatc ttagccatct gcatgagact catgattcct tcctgcatac
     9901 gggctccacc agaggctgtg aataggacaa ctggcaattt ttcgacagtc gcatactcaa
     9961 acaaacgagt gattttttca cctacaaccg tacccataga agccatgata aagttagaat
    10021 ccataatccc aagagccaca gtctgacctt taataagagc agttcctgtc acaacggctt
    10081 catgcagacc tgttttttca cgcatagatg ccagtttctt ttggtaacca gggaaatgca
    10141 agggatcctt gctttcaatc cctgtaaaca attctttgaa ggttcccata tcaatcgtca
    10201 aagccaagcg ttcttgggca gaaatacgaa aggtatagct acagtgcgga cagatacgtt
    10261 cacttcccag atccttctga tagatggtat gcttacagcc tggacactgg gaaaataatt
    10321 catctggaac ctctggctta gcttgaggtt tttccctaac cgaacgattg ggattgattc
    10381 gaatatactt atctttttta ctaaatagag ccattgattc cccttttcgg tttaaactct
    10441 taaagtcatt ttattctttt tcttgatatt taggtaagaa ggtttccatc aagaaggaag
    10501 tatcataatc cccagcaatg acattgcgat ctgaaatgag gtcaagctgg aaatctgcat
    10561 tggtctgcac tccttcaatc tctaattcat agagggcacg ttgcattttc atcaaggcgt
    10621 caaaacgatt ttcgccgtgt actatgattt tggcaatcat actatcataa taaggcggaa
    10681 tggtataacc tggataaact gctgaatcca cgcgcaagcc aactccacca cttggcagat
    10741 agagattagt aatcttacct ggacttggag caaagttaaa ggctgggttt tctgcattga
    10801 tacgacactc gatggcatga ccgcgtagga caatatcttc ttgcttaaca gacaaaggct
    10861 gacctgccgc aatgcaaatc tgttccttaa cgatatcaac acctgaaaca aactctgtta
    10921 ctggatgttc tacctgaaca cgagtattca tctccatgaa atagaaattg ctacttgctt
    10981 catcaagaag aaattcaatg gttcctgcat tctcatagcc aacaaactct gccgctcgaa
    11041 cagcagcagc acctatttca tgacgcagcg tttttccgat tgcaatcgag ggactttctt
    11101 ccaaaacctt ttggttattc ctttgaagag aacaatcccg ttcacccaag tgaatcacat
    11161 gtccatgctc atcacctagg atttgaacct caatgtgccg agctggatag ataacccgtt
    11221 ctatgtacat ggcaccattg ccataattgg ccttggcctc actagaggca gtttcaaagg
    11281 cagaaacgag gtcatctggt ttttcaacct tacgaatccc tttaccacct ccacctgctg
    11341 aagccttgag cataacagga tagccaattt tttcagcaac aatcaaagct tcttcagagt
    11401 tatgcacttc tccatctgaa cctggtataa caggcacacc tgctttaatc atctgagcac
    11461 gcgcattgat cttatccccc atcatatcca taacatgacc agatggaccg ataaacttga
    11521 tacctacttc ttcacacatg gtcgcaaatt tggaattttc actgagaaat ccaaaaccag
    11581 ggtgaatagc ttctgcctca gtcaagactg cagctgatag aactgcatta atattgagat
    11641 aagactctgt tgccttgcca ggaccaatac aaactgcttc atctgccaaa agcgtatgaa
    11701 gagcttcctt atcagcagtt gaataaaccg ctaccgtcgc aatccccaat tcacgtgccg
    11761 cacggataat acgaaccgca atttcaccac gattggcaat taaaattttt cgaaacatgg
    11821 agaacctcct tagttcccaa ttgcaaaagt aaggatacca ctggctgcaa gcttgccatc
    11881 cacttcagcc tttgcttcaa ccacagctat ggtgccacga cgttttacaa aagtcgctgt
    11941 cataaccaat tggtcgcctg gtacaacttg cttcttgaac ttaaccttgt ccataccagc
    12001 gtaaaagacc agttttcctt tattttcagg ttttgataac tctaacacac cagcagtttg
    12061 cgccaaggct tccataatca gaacacctgg cataactggg tattgaggaa agtggccgtt
    12121 aaagaaaggt tcgttaatgg tcacattttt gatagcaaca atggtatcct cgctcacttc
    12181 caagacacgg tccactagaa gcataggata acggtgggga agagcttctt tgattccttg
    12241 aatatcgatc atttgatacg taccaatcct ttaccaaact caaccatttc ttcgttagag
    12301 acgagaattt ccgttaccac accatcctta ggagctggga tttcattcat gactttcatg
    12361 gcttcgataa ttaccaatgt ttgacctttt ttgacactat caccaactgt aacgaaggca
    12421 ggtttatctg gtccagcagc caagtaaacc actccaacaa gtggactctc tacaagattt
    12481 ccctcagtag ccacacttgc ttcagctgga gctggaactt cttctgctac agtctctgct
    12541 ggagcagatg taggagctac tggactcggt gttgctagaa cgggtgctgg agcgacttga
    12601 gttgcaactt caggcacagg tctcgcttca ttcttgctaa actgcaactc atccgtccca
    12661 tttttataag aaaattctct caaacttgac tggtcaaatt gagtcatcaa gtctttaata
    12721 tcgtttaaat tcatacttat ctattctccc aacgtttgaa agcaagaact gcattgtggc
    12781 ctccaaaacc aaaagcattt gaaatagcgt atggaatttc tttctccaag ccttgtccat
    12841 aaacgacatt agcttcgata taatctgata cttcacttgt cccagctgtc attggtacaa
    12901 agttatggcg catagcttcg atggtgacga tagcttctac tgcacccgca gcccccagca
    12961 aatgtcctgt aaaagacttg gttgatgata caggtacttc cttaccaaga acagctacga
    13021 tagcaccact ttctcctttt tcattggcag gagttgacgt tccgtgagca ttgacatagg
    13081 ctacttgctc tggagaaatc tcagcttctt ccaaggctag tttgatggcc ttgatagctc
    13141 cctgaccttc tggatgtgga gaagtcatgt ggtaggcatc acaagtattt ccgtaaccaa
    13201 ccacttcagc caggatagta gctccacgtt tttcagcgtg ttcaagactt tctaaaacca
    13261 acatccctga accttcaccc ataacaaacc cattgcgatc cttatcaaat gggatcgaag
    13321 cacgagttgg atcctctgta gtagagagag ctgttaaggc ttggaaacca gcgatggcaa
    13381 aaggtgtgat agaagcttct gttcctccca ccaacatcac atcttggaaa ccaaacttaa
    13441 tggagcggaa ggcatcccca atcgcatcat ttgatgaaga gcaggcagta ttgatagatt
    13501 tacaaacacc gtttgcacca aaacgcatgg ctacattccc agaagccata tttggtaaag
    13561 cttttggaag agtcattggt ttgacacgtt tgggtccttt ttcatgaagg cgaagtacct
    13621 gatcttcaat ttccttgatt ccaccaatac cagatgcaac gataacacca aaacgatccc
    13681 tattaagagc ctctacatca agattggcat gatttacagc ctcttgggct gcatacaagg
    13741 catataaaga atagttatca aaacggttgg tatctttttt tacaaagtat ttatcgaacg
    13801 gaaaatcttg gatttctgcc gcattatgca catcaaagtc actatgatca aattttgtaa
    13861 tgccaccaat gccgattttc ccagttgcta aactattcca aaattcttct ggtgtatttc
    13921 cgattggaga tgttactcca taacctgtta ccactactcg atttagtttc attcttttca
    13981 cctctagctt tcgctacata cttaagccac catcaatggc aaccacttga ccagttagat
    14041 aatcttggcc tgctaaaaat actgtcaaat ctgcaacctg ctctgcctgc ccaaattctt
    14101 tcatcggaat ctgagctagt gtagcttcct taatcttatc tgataagata gctgtcatat
    14161 cagactcaat cattcctgga gcaatcacat tgactcgtat attccgacta gcgacctcgc
    14221 gtgccacaga cttggtaaag ccaatcaagc cagccttaga agcagcatag ttagcttgac
    14281 caatattccc catcaaacca acaacactag acatattaat gatagcacct tctctggctt
    14341 tcatcatcgg tttcaagact gattgtgtca tattaaaggc accagtcaga ttgaccttga
    14401 gcactttttc aaaatctgct tctgtcatct tgagcataag agtatcttgg gtaatccctg
    14461 cattgttgac caaaacatct actgaaccca gttctgcaat agcttgatca atcatacgct
    14521 tagcgtctgc aaaatctgat acatctcctg aaatgggaac caccttgata ccatagtttg
    14581 aaaactcagc gagcaattct tctgagattg ccccacgact gtttaagaca atgttggctc
    14641 ctgcttgagc aaacttgtgg gcgatggcaa gaccaattcc acgactcgaa cctgtaataa
    14701 agatattttt atgttctagt ttcatttttt tcctttcaaa acttctactt attttagtct
    14761 atttttctaa aagtgctact aaactcgctt gatcttccac atgagctaag tgagcagttt
    14821 gatcaatttt tttaacaaaa cctgacaaga ctttccccgg tccaatctcg ataaagttgc
    14881 ttatgcctgc ttcttgcatg accccaatac tttcatagaa acgaacgggt tccttgacct
    14941 gacgcgtcaa gagctgagcg atgtcctctt tttgcatcac agcagcttct gtattgccga
    15001 ctaggggaca agtaaaatct gaaaaactta cctgagctag agtttcagct agtttctggc
    15061 tagcaggctc aaggagagcg gtgtgaaagg gacctgacac cttaagagga atcaagcgtt
    15121 tggcacctgc ttcttgcaaa agttcaaccg ctcgatcaac tgcaaccact tctccagcaa
    15181 tgacgatttg tgcaggtgtg ttatagttgg ctggagtaac cactccaagt tcagaagctt
    15241 tttgacaggc ttcttcaatg acctctactg gcgtattgag aactgctacc atcttgccag
    15301 agtcagcagg agccgcttct tccatatagg ctccacgctt agctaccaag gcaaccgcat
    15361 cttcaaaatc caaggcgccg cttgccacca aggcagagta ttctccaaga gacaaaccag
    15421 caaccatatc aggctgatag cccttttctt gcaataaacg gtagatagca accgaagtcg
    15481 ctagaatggc tggttgcgta tagcgggtct gattgagttt gtcttcttcc gtatcgatga
    15541 gataacgtaa atcataaccg agcacctgac tcgctcgatc aatcgtttct ttgacaatcg
    15601 gatactgatc atagaaatcc cgtcccatcc ctagatactg ggcaccttga ccagcaaata
    15661 aaaaggctgt tttagtcatt tcttacaact cctgcccagc gagaggcttc ttcttgaatt
    15721 ttcttagcgg ctccgtaata caaatctttt aggatttctt cagctgtttc ttctttagaa
    15781 acaagccctg cgatttgacc tgccatgaca gagccaccct ccacatcacc gtgaacaact
    15841 gctttggcta gggcacctgc tcccatttgt tcaaagattt ctaaatcagg atcttcctgc
    15901 ttaaaggcat ctttttcagc cagttcaaaa tctctagtca actgattttt aatagcacga
    15961 acagcatgac caaagtgctg agctgaaatc gtagtgtcaa tatcccttgc ttttaaaatt
    16021 ttctccttgt agtttggatg ggcattcgac tcttttgcaa ctacaaaccg tgtccccacc
    16081 tgtacagcct ctgcacctag cataaagcca gccgcagcac cttcaccatc cgcaattcct
    16141 cctgcagcaa taacaggaat agatacagct gtggctacct gtcgcaccaa ggtcatggtt
    16201 gttaatttac cgatatgccc cccagcttcc attccttctg caataacagc gtctgcaccg
    16261 attttttcca tgcgtttagc taaagcgaca ctaggaacaa caggaataac gattatccca
    16321 gcttcatgga aacgttccat atacttgctt ggatttcctg ctcctgttgt gacaacttta
    16381 acaccttctt caataacgag atccacgata tcttccacaa agggagataa gagcatgatg
    16441 ttgaccccaa agggtttatc agtcaatgat ttgattttat caatattggc cttgacaact
    16501 tctttcgggg catttccccc accgataatt cctaatcctc cagccttgga aacagcccct
    16561 gccaaatcac catcagcaac ccaggccatc cctccttgga aaataggata gtcaatcttc
    16621 aataattctg taatacgcgt tttcatagtg cctccaacct tccttgctta cgtaatagtt
    16681 cgatttcacc ataatttgac agtcaaacta ttacctaaac aagagggagt gggtttctcc
    16741 ctactccttc tactaatatt ctgcttattt tgcttgctct tcaacgtaag caaccaagtc
    16801 accaactgtt ttcaagtcat tttctgcttc gatttggata tcaaaagcat cttcgatttc
    16861 tgagattact tggaacaagt ccaatgaatc tgcgtccaaa tcatcaaaag ttgattcaag
    16921 tgttacttct gatgcgtctt ttccaagttc ttcaacgata atttcttgta ctttttcaaa
    16981 tactgccatg ataggactcc tttaaaataa atagtttttt ataacaatgt gttcaccaca
    17041 tgattaccta aattgtaaga atgagcgtgc cccaggtcaa gcctccaccg aagcctgata
    17101 gaagaacagt ctggctacca tctaaaggga tgagaccttg ttctacacac tctgaaagta
    17161 aaatcgggat actggctgca ctggtattgc catattccat catattggct ggaagtttgg
    17221 ctcggtcaac accaattttt ctagccatct tatccaaaat acggtcattg gcttgatgaa
    17281 gtagcagata atccaagtct gtcacctcta taggagattc atcaatagtc tgcttgatag
    17341 acttggctac atctcgaatg gcaaaatcaa agactgtgcg tccatccatc ttcaaaaatg
    17401 aatctgcact ttcttgatct gaaaatggag aatgcaaacc tgaatgccca taagttaaac
    17461 actcgctgcg acttccatcg ctattgagac tctcagctaa gaaatgctct tgctcgctag
    17521 cttctaacaa gacaccacca gcaccatctc caaacaacac agctgttgat cgatccgacc
    17581 aatcgactgc cttagagagg gtttcactac caatcaccaa gcctttttga aagcgaccag
    17641 aagcgataaa cttttcagca gttgaaagag caaatacaaa tccactgcaa gccgcggtta
    17701 agtcaaaagc aaaggcttta ttagcaccaa tattagcttg aacacgagca gctgtagagg
    17761 gcatcatcga atctggagta atggtagcta ggatgataaa atccagttct tctcctgtta
    17821 ttccagcttt tgccatcagt ttcttagcaa cctctgtagc caaatcactg gtagattctg
    17881 ttcttgaaat atgcctttgt cgtattcccg ttcgacttga aatccactca tcattggtat
    17941 ccataatctg agccaagtcg tgatttgtaa ccacttgctc tggcacataa tgagaaacct
    18001 gacttatttt tgcaaaagcc attatttcaa atcctccaaa aattggtaaa gattagtcaa
    18061 gcctttaccc atgacagcaa tttcttcctc gctcatgcca tcaataattt tttctaccat
    18121 ggccttgtgg aagcgtttat gcagcctatg aatcaagcga cccttctttg tcaaatgcag
    18181 atgcaccaca cgacgatcct gttctgaccg aactcgctca atgtagccct tacgctctaa
    18241 attgttcaaa cttgtcgtaa cagttccaag agttaccatc aactcttttg acacttgact
    18301 tggagtcaca tctggagcct taccgatgac atcaatcgta tgcatttctt tgatggagat
    18361 atccttaaaa cgactacctc tcaagttcac ttcctcaatt acaaggacat tgttaaatat
    18421 agatgttaaa tattcattga ttcgttggta gtccattttt catatccctc cttcttcaaa
    18481 aaacttttac aatcaaaaca tttgacagaa agaattatat caaaattcaa agaatgatgc
    18541 aagtattttt tactttcctg taaatttagg tcttcttctc tccgaatgag ctcgcactcc
    18601 ttctttgaaa tcctctgttt gagctaagga tttctgtagg ttcagttcta aagtagcgta
    18661 accctgccag tctttaaatt ggctctccca aaccaacttc ttaatggcag cataggaatt
    18721 acttgaagca cgtcttaatt ttttaagaag ctgttctctc gtcttttcaa gtttttcagc
    18781 ttcagaaacg cggtaaacca acccccattc tagggctttt tctgccgtta aagcctctcc
    18841 tgtcatagct aattgagcag cacgcgtcac accgatactg cggctcaaga gatgaattcc
    18901 ccctgcatct ggagccaaac caacaccaac aaaggcttgg ataaacttag ccttatccgt
    18961 cgccaaacag aaatctgccg caacagccat attcgctgcg gcacctgcaa cagcaccgtc
    19021 aacttccatt aaaacaggtt tggctatttg cttgatttta taagaaatcg tattgaccaa
    19081 ctctgcgatt tttgtcaatg atggaatatc atcctcatcc actgcccgct tcatctctac
    19141 caaatctccc ccaactgaga agacctttcc attggcattg attaagataa aatgcacagc
    19201 tggattttct tctgccaaag tcagagcttc taaaatctcc tcacacatgg gaatatgaaa
    19261 accatttgcg acctcaggac ggttcaaggt aaggattgcc aagtcctctt caagctgata
    19321 aataatgtgt tccatcaggg ctccttttta ttttataagc agtttatact cttcgaaaat
    19381 ctctttaaac cgcgtcagct tccatctgca acctcaaagc agtgctttga gcagtctgcg
    19441 gctagcttcc tagtttgctc tttgattttc attgagtgtt aaattatttc actgtcaaag
    19501 tatatctttt ttaggagcag aaagcaagaa aaaatcgact gaaagtgtct cagccgataa
    19561 gaaaggctcg ctttaggcta gaaagcatct tattttcttc attgaaaaaa gcctttcttt
    19621 ctgctataat cgtataaaat acttacttta ggagttctta tgaaagttgt taaatttgga
    19681 ggtagttctc ttgcctctgc tagtcaatta gaaaaagttt taaacatcgt caaaagcgat
    19741 tcagagcgtc gttttgtagt cgtttctgca cctggtaaac gcaatgctga agatactaag
    19801 gttacggatg ccctgattaa atactaccgc gactatgttg cgggtaacga tattagcaag
    19861 agccaaagct ggattatcga ccgctatgct gctatggtta gtgaattggg actaaaacca
    19921 gctgtgctag aaaaaatttc taaaagcatt cacgccttgg ccactcttcc tattgaagaa
    19981 aatgaatttc tctacgatac tttcctagca gccggtgaaa ataacaatgc caaattgatt
    20041 gctgcctact ttaaccaaaa tggtatcgat gcacgctata tgcaccctag agaagctggg
    20101 attgtggtca caagtgaacc tggtcacgct cgcatcattc catcaagtta tgacaagatt
    20161 gaagaattga caaacaccaa tgaagtcctt gtcattcctg gtttctttgg tgtcactaag
    20221 gaaaatcaaa tctgtacttt ctcacgtgga ggttctgata ttacaggttc tatcattgct
    20281 gctggtgtca aagctgacct ctatgaaaac tttacggacg ttgatggtat ctttgcagcc
    20341 caccctggta ttatccacca accacactcg attcctgagt tgacctaccg tgaaatgcgc
    20401 gagttggcct atgcaggctt ctcagtcctt catgacgagg ctcttcttcc tgcctaccgt
    20461 ggaaaaattc ctctggttat caagaatacc aacaaccctg accatccagg tactcgtatc
    20521 gttctaaaac acagtaatga tgaatttcca gttgtgggaa ttgctggtga ctcaggcttt
    20581 gtcagcatta acatgtcgaa atatctcatg aaccgtgagg ttggatttgg ccgcaaggtt
    20641 ctgcaaatcc tggaagaact taacatcggt tgggaacata tgccaacagg tatcgacgac
    20701 ctttctatca ttctccgttc tcgcgaacta actcccatca aggaagaaga aatcctgcgt
    20761 cagttggttc aaaagactaa agtagatcat gcagaaatcg aacacgacct ttctatcatt
    20821 atgattgttg gtgaaaaaat gaagagccac atcggagtga ctgctactgc gacacgcgct
    20881 ctatctgaaa acaaaatcaa catccagatg atgtctcaag gttctagtga agtttctatc
    20941 atgtttgttg tcaataaaga ccaagagaaa gcagcaatta aagccctcta caatgccttt
    21001 tttggaaaaa gtaaggaaga ctaagcatgg cccaatcact taacaaaaca gtactcctca
    21061 gtacgacagg cacttcctac ctctctatcg ctgggaaagt tgggaaattc cttgtcggag
    21121 atcaggcttt ggaattttac ccagatgtca atgtcgaaca atttatccag attccttgga
    21181 gccatatcaa tcagattgga gccaatgtca ctggacgcaa aatcagccgc cacttcgaag
    21241 tctttacaga caaaggaaaa ttcctctttg cttcaaaaga ctcaggtgcc attctcaaaa
    21301 ttgcacgcga aaaactcggc aatgacaagg tcgtcaaact tccgaccctg attcagacaa
    21361 ttagccaaaa atttaaaaat ctatttgcaa aaaagtagaa actttagtat aatcatagca
    21421 acggataagt aggttatctt cttctttcag aaagtctgcg ggtactgcga gcagatagga
    21481 gggataggtg aaattctacc gttagtaaca attacataca caatcaagtg cacacctgtg
    21541 aagttggatg gaaccgtggc cctgccactc caacgttttg tcaggcgtgc ttttttcata
    21601 aaggagttct tatgttagat atcaaacgta ttcgtacaga ttttgaagct gtcgcagaaa
    21661 aattagctac acgtggtgta gatgctgctg tcttgaatga aatgaaagaa atcgatgcta
    21721 aacgtcgtaa catcttggtc aaggttgaaa ctctcaaagc agaacgtaac acagtttctg
    21781 ctgagattgc ccaagctaag cgcaacaagg aaaatacaga tgacaagatt gctgccatgc
    21841 aaaatctatc tgctgaggtt aaagccttgg atgctgaatt ggcagaaatc gatgctaaat
    21901 tgacagaatt tacaacgact cttccaaata tcccagctga cagcgttcct gttggggctg
    21961 acgaagacga caatgtggaa gttcgccgtt ggggtactcc acgcgagttt gacttcgaac
    22021 ctaaagctca ctgggatctc ggtgaagacc ttggtatcct tgactgggaa cgcggtggta
    22081 aggtaacagg cgctcgcttc ctcttctata aaggcctcgg tgctcgtttg gaacgtgcta
    22141 tctacaactt tatgttggat gaacatggaa aagagggcta tactgaagtc atcacacctt
    22201 acatagtcaa ccatgattct atgtttggta ctggtcagta tccaaaattt aaggaagata
    22261 cttttgaact cagcgatacc aactttgtct tgattccaac tgctgaagtt cctctgacaa
    22321 actactaccg tgatgaaatc ttagacggca aagatcttcc aatctacttc actgctatga
    22381 gtccgtcatt ccgttctgag gctggttctg ccggtcgtga tacgcgtggc ttgatccgtt
    22441 tgcatcaatt ccacaaggtt gaaatggtca aatttgccaa accagaagaa tcttacgaag
    22501 aattggaaaa aatgacagcc aacgctgaaa acattcttca aaaactcaac cttccatacc
    22561 gtgtcgttgc tctctctact ggagatatgg gcttctcagc tacgaagact tacgacttgg
    22621 aagtgtggat tccagcacaa aacaattacc gtgaaatctc aagctgttca aacacagaag
    22681 atttccaagc ccgtcgtgcc caaatccgtt accgtgatga agcagatggc aaggtgaaac
    22741 tccttcatac cttgaacggt tctggacttg cagttggacg tacagtggct gcaattcttg
    22801 aaaattacca aaatgaagat ggttctgtga ccatcccaga agcacttcgt ccatacatgg
    22861 gtggagctga agtcatcaaa ccataaaaaa taaggtttag ctatttctag ctagaccttt
    22921 tttcgtaacc aaatcagata agcacctagt acaaagaata aaatagttag gcatataatg
    22981 gtttcagcca ataccaggta atccagaaat ggaagtttca aaattccctg agccatcttg
    23041 agcgaggtcg ctgtgataat ggttgggaaa gtgagggctg agaaggctgg ttgaaaacct
    23101 tgttttaaaa tgttgggcag acgagttaaa acaaagaaaa agaaggattg agaagccaaa
    23161 atcatgacaa tcaagaccca agtcggcagg ctggttcctc ctactcgaac tagagaagcc
    23221 aagagtagag agaaaggagc acagtagatt ccttcttgtc caagcaaggc tagtgggagt
    23281 ggatgtttct ttaaatcgct ataaataagg ggatagagat agaaggtcaa gagaaaacca
    23341 aaactcaagg tcgcataggc aatttcgata atacctacca gaggataggt caaggcagcc
    23401 actgctatcc ccacatagag aaccgtccaa cttggagtgg catgaaccct ccgccctgaa
    23461 caagcaaact tgatggtaaa accagcaatc aaggtcaaat ccaagagaaa tgaaaaccac
    23521 caaatccctt gtgctaccaa aggaagataa gagaatacgc gaaagacata ggtcgataaa
    23581 atcatcccag ccataggaaa ggttgccatt cctgacaaaa gagggggctt ggtcaattct
    23641 tgcttggttt ctttccaatt aaagagatgc agaattagaa agtaaatcca taaaaccaaa
    23701 ccagtcagac taaaaagatg ggatagaacc ggcaacgtat ctaaaataag atttccagct
    23761 cctgccaaac ctagcaaaca acctgaaaat actaagggga gttttttcat cctaacctcc
    23821 aataatcatg ttagtttcag tataacataa aagcgcttaa atgaggattt aaaaaaacga
    23881 agtccgctta tttcagactt cattttactc agatatgaat taggcataag gttgcaattc
    23941 tggattaatt ggtgtattag ctaagttgtt ggcatagtta cagaggattg ctaggctgac
    24001 accaaaaacc acatccaagg cattttgttg agtgtagcca gcttctaaaa actcagacaa
    24061 ggcttcatct cctacacgac ccttggtatt gataactgcc aaggtaaact tagctagggt
    24121 atccaattta ggatctgttt caattggagt acgattgcga agagcttgaa tcaagtcatc
    24181 attcatctgg atttgtttga tggaaaaggc tgtgtgacct gcgacacaga aggcacaacc
    24241 attggtcacg gctgccgtga tttgcaccac ttcacgctca acgggtgtca ggctgttgcg
    24301 acggtggata gatgagacaa tttggtaggc ttctaaaaca gtcggggcat tggccaagag
    24361 accgattagg ttgggaatat agccattgtt gtctttttct actgtttcaa gaatttcttt
    24421 cacttctgct ggtgctgact ctactgtatg gatagtaaat gttgtcataa gatacctctt
    24481 ttcttattat tgacactaat attattggaa aatcttataa aatcctgatt cctaagttta
    24541 tctaagataa agctttattc tctcataaga ttttcgttgt tatattagtt tatcacactt
    24601 ccaatcactt gcataatata tattatatat caggctgata aaaattattt ataggcaaaa
    24661 aaatcacacg agctgtgtga ttccattatt tgtcaaaata ctttttagtt tcagcaataa
    24721 cgacttgcga caagaccaag agggcaatca agtttggcag agccatcaag gcgttaacga
    24781 tatctgcgat aatccagacc atatccaact cgataaatcc tcctaacaag accatgagca
    24841 caaaaaccac acggtagagc cagataaagc gaaccccaaa gaggaactca aaacagcgtt
    24901 ctccgtaata gttccaacct agaatcgttg taaaggcaaa aagcacaagg aagatggtca
    24961 agagggcagg cccaaagtgt gaaaagactg ttgagaaagc tgactgagtc aaggcaaccc
    25021 cattcaagtc accactccaa actccagtta ccaagatggt caaaccagtt agagtacaaa
    25081 tgatgagggt atcaataaag gttcctgtca tggaaatcaa accttgctct actggttcat
    25141 ttgtcttggc agctgcagct gcaataggag cagaacccag accagattcg tttgaaaaca
    25201 caccacgcgc cacaccattt tgaatagcca tccgaacgct agcaccagca aatccaccta
    25261 ccgcagcaag gggactaaaa gctgaggtaa agactaaagc gattgtgcca gggatttttc
    25321 cgatattaaa gaaaataact gtaagagttc ctaagatata aatgatggcc ataaaaggaa
    25381 caacagtagt tgaaacctta gaaatagact tgagtccacc aaagactgca atcgctacaa
    25441 agacagacaa gacgagagct gtgatggctg gcgaaatcgt cgttgtattt tggatagatt
    25501 ctgtaatcga gttgacttgg gtgaaggttc cgattcccaa gagagcaacc aatactcctg
    25561 ctactgcaaa caaaacagca agtggtcgcc acttttctcc catccctaga aggatataat
    25621 gcatgggacc tcccgctact gcaccatggt cgtccttggt gcggtatttg atggccaaga
    25681 gtccttccgc atacttggta gccattccaa agaaagccgc catccacatc caaaatagag
    25741 ctcctggtcc accaaccttg atagccgtcg caactcctat gatatttcct gttccaacag
    25801 ttgatgccaa ggctgtacac agagctgtaa aactggatac atcaccatgt cccttatcct
    25861 ggataaaaat aagctgaaag gccttgggca gacgcaaaac ctgcaagagt cctagccgca
    25921 tggttaggta aatccctgtt ccgaccaata aaatcaagag gggcggtccc caagcaaaag
    25981 catcgattga tttaagcaat tctaacattt ccttctccta tcgtttcaac cccaaaagaa
    26041 agagcacatg caagatacat gtactctgga atgcttagat aaatgctaaa aagcggtcta
    26101 tcctagctct gtccttttac ctgagagttt gagcagttgc ctgccttgcc ccttcggtgc
    26161 ctttacggtc tctccagagt tccgtccatt tacagtcatg gaaaatcaaa cgattcccca
    26221 cttctattaa acttcattcg gtgttggtat ttaattgatt ctaattttac aaaaaatgtt
    26281 ggcttttgtc aatgtgttta ttagtaaaaa ttagttcaac agtttttact ttataaagtc
    26341 cagaatactg ctatccttta aaagtgacaa tagtcgcacc actgcctcca gcattttgtg
    26401 gggcatagcc gaaactcttg acatgtttgt ttctttgcaa gtatttggta actccttcac
    26461 ggatgactcc tgttccgata ccatggatga tatcaacttg agccatattg ttaagcaagg
    26521 cttggtcgat gaaggtatct agctcattca tggcttcttc atagcgcttg cctcgaagat
    26581 ccagtctagc ttgaggtcct cgcccagaag ttcgtttcac aacattgacc tgtttcttct
    26641 tgactggttt ttcttgctgg gcttgaacaa gatcaaactc tttctcttcc aaggtcatct
    26701 taatcaagcc aacttgggct tcccagcggc cgtccttgag ttgactggtc aaggtaccac
    26761 gctgaccata actgagaacc acgatatcat ctcccacctt tggagctcgt tttttcttgg
    26821 ccttttgaag gaccttgttt ttagacaagt ccactttttc aggagccaat tttttcaact
    26881 tggctttggc ttcaatgatt tcgtggggct tgagttggga tttactgtgg agatttttga
    26941 gaatctggtc actttcactt agggccatat ccacaatctc agcagcctgt tcacgcgcct
    27001 tgttaagctc ggtttccttt tcacgattaa gctcgttgta gagttttttt agcacacggt
    27061 tcatcttgag attttcttgc tccacctcac ggatattgtc caagcgtttg cggctttcca
    27121 gcgtctgctc ttctagttgc tcaatgatac gattgacgtc attgtcctga tcgatctgct
    27181 gactggcatc tcctacgata acttcagata ggcctagacg tttggcaatt tcaaaggcat
    27241 tacttcggcc aggaacaccc tgcataaagc gataggtcgg gcgaagagtt gcagtatcaa
    27301 actccatact ggcattttgc acaaaggctg tctcaatacc gtaggccttg agttctggat
    27361 agtgggtcgt cgccatggtc ttgatttgac gcaggcgaag gtcctccaga atagccatgg
    27421 caagggctgc tccctcttgg ggatcagtac cagcccccaa ctcatccaaa agtaagagtg
    27481 aatgttggtt gaccttgcca agaatatcca cgatattggt catatggcta gagaaggtag
    27541 acaagctctg ctcaatagac tgctcatctc caatatcagc aaagatttct tcaaaaatac
    27601 caacacgact tcccttgtct gctaaaatcg gcaatcctga ctgggccatg acctgtgtca
    27661 agcccagagt tttgagcatg atggtcttcc cacctgtatt gggacctgta atgacaatag
    27721 ctgttaaatc ttgaccaaaa tagacatcat ttgcgacggc atttttgacc aaaggatggc
    27781 agacatggag cagttgaatc tcttgatttt ctgacagctg aggcacgact gcttgtcttt
    27841 cttggataaa tcgaaccttg gcacgaatca agtccagatg accgataatc caagcgtcat
    27901 tagcaatctc agccgcatga gggcggacac gctcagaaat ttcttggaga atgcgaagca
    27961 tttcatagcg ctcatctgct cgcagactag caatttcttc gctcagtttg actacctcac
    28021 gtggttcgat atagacggtg tttccactag cagaaatatc atgaacgaca cctgcaatct
    28081 tattgcggta ggtgtttttg actggtaaaa cctgacggcc atttctgcta gcaacaattc
    28141 cttccgtcaa catctgcgct ttttgcttga gcaagtcttg taaaacatcg cgtacctgac
    28201 tctcgctatc atgtattttt cgacggattc gcgccaattc ttcactggca aaattttcaa
    28261 tgaaacccgc atcattaaag gcctgaagat ttccttgtaa ttgcggaaaa tcatgtaatt
    28321 tctcaaacca aagggctaat tcttccaagc tgacattttc cagattggcg taaaaacttt
    28381 gaagttctcg gctggtaaga agcacgcgtt tcaagagtag gaactcctcg atattgagat
    28441 ccgctcccat ctccaacctc ttgcagactc ctgcaatttc cttagttgag agaatagtaa
    28501 aatgcggttg ctcgacgaaa agagcctgca tttctttcat ctcagcaaaa gcctgtttga
    28561 ttttatctgc tttggcagtc ggagccagct gtctcaattg ctccaagccc tgctcggtca
    28621 acaaatgagg ctcaaacaag gccttgacct tatcgaactc taatgtttct aatattttct
    28681 tattcatctt tatttccttg tctttgaatg tctaggtgtg gtagcttttt acattctgat
    28741 agattcgagt caaatctgta aacaaagggc taggaaaact cctgcccttt ttatccgatt
    28801 aaatttgtca cccagatttg tttgagccaa ctggttgtta tcggtatgct ctggatgatg
    28861 tgttttgcga cgatactctt ttcaagagga ttttgtataa ctgccatggg gatggtcgcc
    28921 aagattgtca aggccatttg caagacaaat aaggtcacca acatggacaa gatacctgct
    28981 gaaacttgga acaacttacc acccagtttt ttgctaggaa tcaagtgtaa gagaagacca
    29041 agcaaacgac caatgctata gacaatccca aatacaagca agtagccgat acctgcataa
    29101 aagaccttat ccagctgaaa gagttgatcc gatgggaaaa agaaagtccc ctgaccttcc
    29161 tgcgaatttg cataagggag caataaatgg aattgctctc caagcccctt ataaaactgg
    29221 ccagccataa aagccgatgc catggctgaa atcaggtaat aaacctgtaa gagcaggcct
    29281 ctccgatagc cgatataaaa tccccaaacc aagaccaata gaagaaggaa tgaaatcata
    29341 aggaatcctc aatcttgctc tgttcttgct tacaagtcac aagcttgtga cggagttctt
    29401 ctagctcttg ctccttatcg tcaaattcaa tctcacggct gagctgagtt gataaacagt
    29461 tgactgccaa caaaagagcg attgtttcat catctgcgct aggcatttgt tctttaattg
    29521 cttggtattt ttctgtcgca accttagcga tttcctccat aaaaaggtta tcatgttcgc
    29581 ttgtcaaggt taacgatttt ttcccgaatg taaatttgaa tcgatttaga tttgccataa
    29641 aattcacctc acgatattat accaaaattc gctaattttg tcagttttta caaattttac
    29701 tgcttttgtg gtacaataga aactatggca agtatcacac tcacaccaag cgaaaaggat
    29761 attcaggctt ttcttgaaca ctatcaaacc agtctggctc ctagcaagaa tccctatatc
    29821 cgctactttt tgaaactacc tcaagcaacg gtttctatct atacttctgg aaaaatcttg
    29881 cttcagggtg aaggggctga aaaatacgcc agtttctttg gctatcaagc tgtagagcaa
    29941 accagcggac aaaatcttcc tttaattggg acagatgagg tgggaaatgg ttcctacttt
    30001 ggtggacttg cagttgtggc tgcctttgtc acacctgacc agcacgactt tttacgaaaa
    30061 ctcggtgtgg gggattctaa gactctgacc gaccaaaaga tccgtcagat tgctcctatt
    30121 ctcaaggaaa aaattcagca ccaggcactc cttctctcac ccagcaagta caacgaggtc
    30181 atcggagacc gctacaatgc tgtttcggtt aaggttgccc tccataatca ggctatctat
    30241 ctcctccttc aaaaaggtgt tcagcctgag aaaattgtga ttgatgcctt taccagtgct
    30301 aaaaattatg acaagtactt ggcacaagag gccaatcgtt tcagcaatcc tatcagctta
    30361 gaagaaaagg ctgagggcaa atacttgtct gtcgcagttt cttctgtcat tgcgcgtgat
    30421 ctctttctgg aaaatcttga aaatctggga cgagaactgg gttatcagct tccaagtgga
    30481 gctggaacgg cttctgacaa ggtggctagc cagattttgc aagcctatgg tatgcaggga
    30541 ctcaacttct gcgccaaatt gcactttaaa aacactgaaa aagcgaaaaa acgcttagaa
    30601 aggtaagtta tgaattcatt taaaaatttc ttaaaagagt ggggactgtt cctcctaatt
    30661 ctgtcattac tagctttaag tcgtatcttt ttttggagca atgttcgcgt agaaggacat
    30721 tccatggatc cgaccctagc ggatggcgaa attctcttcg ttgtaaaaca ccttcctatt
    30781 gaccgttttg atatcgtggt ggcccatgag gaagatggca ataaggacat cgtcaagcgc
    30841 gtgattggaa tgcctggcga caccattcgt tacgaaaatg ataaactcta catcaatgac
    30901 aaagaaacgg acgagcctta tctagcagac tatatcaaac gcttcaagga tgacaaactc
    30961 caaagcactt actcaggcaa gggctttgaa ggaaataaag gaactttctt tagaagtatc
    31021 gctcaaaaag cccaagcctt cacagttgat gtcaactaca acaccaactt tagctttact
    31081 gttccagaag gagaatacct tctcctcgga gatgaccgct tggtttcgag cgacagccgc
    31141 cacgtaggta ccttcaaagc aaaagatatc acaggggaag ctaaattccg cttctggcca
    31201 atcacccgta tcggaacatt ttaagaaacc taagaggccg agaatcacca atctcagcct
    31261 cttcttctat cgtgagaaaa tgattggtac tatctaaact taccagaaca gaaacacctc
    31321 aactctcacc tattcatgca aaggaatttt atggaagttt atttttcagg aactattgaa
    31381 cggattattt ttgaaaatcc cagcaatttt tatcgcatcc tcctcctaga aatcgacgat
    31441 acggacgcag aggattttga tgattttgaa atcattgtca caggaaccat ggctgatgta
    31501 attgagggcg aagactatac tttttggggg caaattgtcc agcactccaa gtatggagaa
    31561 caactgcaaa tcagtcgtta tgatcgcgca aaaccaacta gtaagggctt ggtcaagtac
    31621 ttttcaagta gccatttcaa ggggattggt ctcaagacag ctcagaaaat cgtggatacc
    31681 tatggcgaaa ataccattga cgaaattttg caacacccag aaaagttaga aggcatcgca
    31741 ggactctctg ccaaaaatcg cgaggctttc gtctccactc tccgtctcaa ctacggaacg
    31801 gagatgattt tggccaaact agccaactac ggcattccca acaaactagc ctttcagatt
    31861 caagactttt acaaggaaga aacccttgat gtggttgaaa attatcccta ccaactggtt
    31921 gaggatatca agggtttggg ctttaccatt gctgaccaac tagctgagga actaggcatc
    31981 gaaagtcagg ctcctgaacg cttccgcgcc ggtctagttc acagtctttt tcagacctgt
    32041 atggaaacag gggacaccta tgttgaagca cgggatttgc tggaacaaac ccttactctc
    32101 cttgagtctt cccgtcccgt ggaactagac cccagccaag ttgcccaaga gctctcctac
    32161 ctgatcgaag aagacaaggt tcagcagatt gataccaaga tctttgacaa cagcctcttt
    32221 ttcgctgagg aaggtatccg cagtcacttg attcgtatcc ttgaaaaagg aaaacagaag
    32281 agccaagatt tagaaactat tcaaaagcat atcactactg tcgagcaaga actggggatt
    32341 gagtatgata acattcaaaa acaagctatt tgtgacgcta tccagaacaa ggtctttatc
    32401 ctgacaggtg ggcctggtac tggtaagaca actgttatca atggaatcat cgctgtttat
    32461 gcccttttag aaggacttga cttcaggaag aaaaacaatc tgcccattct tcttgctgct
    32521 ccaactggtc gagctgctcg tcgcatgaat gaattgacag gtttgcctag cgcgaccata
    32581 catcgccact tgggaatgac aggtgacgat gataccagtc atctggaaga ttacctagat
    32641 gctgacttta tcatcgtgga tgaattctct atggtggata cttggctggc caatcaactc
    32701 ttctccaata tctcttctaa cagtaagatc ctcatcgtag gtgacagtga tcagctacct
    32761 tctgtcagtc ctggacaggt tctagcggat ctgcttcata ttcctttgat tcctcagact
    32821 cgcttggaaa aaatttatcg acaaagcaaa gaatcaacca tcgtcaccct agctagtcag
    32881 attcgacagg gcatcttgcc agctgatttc acccaaaaaa aagctgaccg ttcctacttt
    32941 gaaattgcta gtggccatat tcctgccacc attgaaaaaa tcttaggtgc cgccctcaga
    33001 aatggtattc ctgcccgtga tatccaagtt ctggctccta tgtaccgagg gacggcaggg
    33061 attgatgcta tcaatcagct catgcaagac ctgctcaatc ccccacaaaa agatcaactc
    33121 agttttgaag ctcctcagtg ccactatcgt aagagagaca aggtcattca tttggttaac
    33181 gatgctgaaa tcaatgtctt taatggggat ttaggagcta tcacagacct gattcctggt
    33241 aaatacaccg aatcgaaaca agacgagatt gtcattgatt ttgatggtaa tgaagtctct
    33301 tacccccgta acgaatggta caagattcgc ttggcctatg ccatgagtat tcataagtct
    33361 cagggaagtg agttcccagt tgtcatccta ccgattacta gtgctagccg acgtatgctg
    33421 gagcgaaatc tcatctacac agccattaca cgtgccaaaa gcaaactcat cttactaggc
    33481 gaattacaag ccttcgacta tgctacccaa cacatcggaa ctgcccgaaa aacctatctg
    33541 attgaacgct tcagtgatct actggagaat gttgaagaaa agcaacaagc tgtctctgaa
    33601 acagtcacat caagtgcctc tgaacaatcc tacatcctaa ccgaagaaaa ctgggaccgc
    33661 atcccagcca tgattgggat tacagacaca gacctcaaag agatttttgg aaaatagtgc
    33721 atcagaaaac ccaccaattc aggtgggttt tctgtttatt aagattattt tactgttgct
    33781 gtgcttgtaa tcaattcaac agcttttttg attgtgatat catgtttcaa catgtcagct
    33841 gaaagcaagc tttgtacttg agcaacttcc atgttgtagt ctgctgccaa ttgctcaact
    33901 tctttttgga tttcttcttc tgaagcatca aatccttcag ctttggcaac tgcttcgata
    33961 acaaggttag tcttagtacg tgactcagct tctgcttggt attggttgtg aaggtcttct
    34021 tgagtagttc cagtgatttg gaagtacatg tcagggttga tcccttgacg ttgcaagttc
    34081 ccaaggaatt catttactga acggtgaact tcttcgtgga tcatttcttc tggaagttct
    34141 acgatttcag cattttctac agctgtatca attgctgcac cttcaactgc atctttgtaa
    34201 gcttcttctt tagcagcagc caattctttg cggtattttt ctttcaagtc agcaagtgtt
    34261 tcaacttctt catcaatgtc ttttgcaagt tcatcgtcaa gagctggaac ttctttagct
    34321 tttacttcat ggatagttgt cacgaattta gcttctttac ctgcaaggtc ttctgcttgg
    34381 tagtcttctg ggaatgttac gataacatca acggtttcgc cagctgagtg acctaccaat
    34441 tggtcttcga aaccagggat gaattgacct gaaccaagtc caagtgagaa gttttcacct
    34501 tttccgccgt caaattcaac accgtcgata gaaccaacga agtcgatcac aacagtgtcg
    34561 ccgtcttcag cagcagcttc cttgataacc aattcagcca ggttgttgcg ttcgcgttcg
    34621 atacgctctt cgacatcagc gtcagttact tctttttcta catcaactga tacttcaagg
    34681 tttttgtagt cacccaattt tacttcaggt tttgtaacaa cttcagcagc gataacccag
    34741 tcttgacctt tttccattga agttacgtca atttttggtt gggcaaccac ttcaagacca
    34801 gcttctttta cagctgcttc ataagcgttt ggcaaaagag cgttcataac gtcttggtaa
    34861 agtgattctt caccaaattt tttatcgaag ataggacgtg gaaggtgacc tttacggaaa
    34921 cctggaacat taagagattt cttcactgac ttgaagacac ggtccaattc tggtttgatt
    34981 tggtcttgag agatagtgaa agtcaagaca ccacggtttg tttctttgtt ttcaaatgat
    35041 acagacattc tgtcatttct ccttaaaatt ttttaaatac agtctattat aacattttct
    35101 ataaataaaa tctagactaa tgcagacaat tatagacaac aagccttttt cctaactaaa
    35161 acactcataa agtatagaca attttagact actttggata tcttttggtt agtcattttc
    35221 caaaactaat ttatctaatt tttaagttat atttgacttc atcttctcag taacatgagt
    35281 ataaacactt aaaatctttg tttcattagt ataatctaca cgatccatta tcgctattat
    35341 aggtacttcc aattcagcaa gcaaacttat atgcgaatat ctaaaaacat gagcagtcaa
    35401 tacaaaatca tctttcttaa tttcactttt cctaaacctg tttttcaaaa agtaattgaa
    35461 acaagttatc attaagggag aaccattatt tgtaaatata taatcacctt cttctaaaag
    35521 aagatattct tttaaaattt ctaacactct atcactaata ccaattactc tatatgaagc
    35581 taaacttttc ggactatcca aaaacacttc gttattggac gattacatta tagtaaaacg
    35641 aaataagaac aggacaaatc gatcaggaca gtcaaatcaa tttctaacaa tgttttagaa
    35701 gtagatgtgt actattatag tttcaatcta ctatacaaga cgaaattgaa gaaatctttc
    35761 cattataaaa cgcatattat caaggttttt aaacacctaa taatatgcgt tttttcctat
    35821 tttaaagact tttatccacc tattatacaa agttaagtat ccatcacagt ttacaattag
    35881 ccgtcattac ctaacccatt caccatcctt caagagagta acctttaaga accgaataaa
    35941 taaatggcaa atttcgttca tttaatttaa ctgcactgtt aatttgatta gctccatctc
    36001 ctaaagtatg cactcctact acgcggttac tagcatcata aactgtagat ccactagacc
    36061 cctctaaagt atcaacttgg tagtccaaga acatgccatc atcacttaaa acttgttttt
    36121 tatctgtata catttgatga attttaaaat tatatgatgg atagcctgtg atagtcacag
    36181 ttattcctgt caaatttttt tgactagtag gaagacccaa agtccctaat tttgcaccaa
    36241 tgggctcttc tagaattaat aaagccaagt catattccct tgcatcctta gaatttaaat
    36301 ttctaaattc cttcaaataa cgaacttctt ttacttttat ccgaccaaac ggcacactat
    36361 ttggagtacg agcaggagta acatatagtt cttctgcatc tttaccaaac tcatgtttat
    36421 aaatattatg agcagcagta ataaggacat tatcctttat aaaattggca ctccctcgat
    36481 aagttacatc tttaccattt ttcacaccac gaaattctga ctctacataa gctgatgtag
    36541 aataaggata ttgtaaagta ttttttacct taactaaatc atttttacca ataatgactt
    36601 ctgactgatt tgtataatat tgaccataag tcggtgaaac attgggaagt gaaaaattat
    36661 tagttcctgg actatcttgt aatgtctcac ttacctcata ttcttcacct gtactagaaa
    36721 taacactcaa agcagatact gtcgataact ggctagccaa taaagtactc gcaataattg
    36781 aaatacccaa ttttttataa acagttttct tcattattgt atcctcctaa tgtaattata
    36841 gcgtactatt ctaaatttct taatctacta tagaatcaag aaatctacca ccttctttaa
    36901 ataccctcca ttatcacata aacaggtaaa cttttcaatt aatgactgcg cttttcaatc
    36961 acgctagagg tacttgcttg cttctttgat actaagttca gccattcttt ccttgttttt
    37021 ctcaataaag catgttaccc aagtgggatt cgttttggag tagtctcgca gagtccagcc
    37081 aatggcttta ttgataaaaa attctgtttg gttcaagtta tgaagtagaa tcttttccat
    37141 taattgagta ttggtcttct cttttcttaa caactggtgg tcaatagcga cacgtctcag
    37201 ccagatatta tctgataggc tccattttat actcaatgaa aatcaaagag caaactagga
    37261 agctagccgc agattgctca aaacactgtt ttgaggttgc agatagagct gacgtggttt
    37321 gaagagattt tcgaagagta ttaagattat ttcttctagt tcagagtgtt catacaccaa
    37381 actccctact actcgatcta ggatatctac cgtgtcccac caggattttg tcacgactaa
    37441 ctgctctagc ttaggcaaat cggtttcctt tagataagac tgcattgctt tcaaatagtt
    37501 agcagccaca tattggtatt ctctaggatc cttttcccag caagtgtctg caaaatccca
    37561 atcgataatc tttgtttttt tcgcttctgg aaaatatttt tatagagttt atttctttca
    37621 ggcaccgcaa tacctagaaa agaaaattga tggcgcatat aggcttccat ggaccttgct
    37681 tttttagagt cttttgctgc ttctagctcc tcaagtaaat ctgctaaact catctaaaac
    37741 tcctcttgcc ccaccaaatg gtgctgaaag gcatagacag tcgcctgggt acgatcgctg
    37801 acttcaagtt tggcaagaat attggacacg tgggtcttga ccgtcttgag agagataaag
    37861 aggtcatctg cgatgcgctg attttcgtag cccttggcga tgagttggag aacatctcgc
    37921 tcacgcgcag tcaattcttc atgaagttcc atatgattgc ggtggtattc aaccttcttg
    37981 ctaacctctt gctcaatggc cagctcgcca gcagctacct tactgacggc atgaagcaat
    38041 tcatctgcac tagaagtctt gagcatatag cctttggcac cagcatctaa gactggcatg
    38101 attttttcat tgtccaaata agaggtcaca atcaaaatct tggcttcagg ccattcttta
    38161 aggattgcta aggtcgcgtc aatcccattc atctcaggca tgacaatatc catgacaatg
    38221 acatctggac gcagttccaa ggccaagtca atcccttgag acccgttgga cgcctcaccc
    38281 acaacttcta catcgtcttg gaggtcaaag tagcttttca agcccaatcg gaccatttca
    38341 tggtcatcta ctagtaaaat tttcatcttt actcctttat cattccttat ctaacagggg
    38401 aatacggata tcaactgcca gcccttgctt gggagctgtt aataactgaa ccgtccctgc
    38461 catatcttca acccgctcct tgatatttcg cagtccataa ctcaagtcgt ctaagctccc
    38521 taaccggaaa ccaatcccat tgtccaccac cttcagttgc aattcaacat ctgtctgata
    38581 gaggtagaca tctaggcaag atgcctgggc atggcggagc gtattgctaa tcaactcttg
    38641 caggatacgg aagatatgct cctcgatttt cttaggcaat ttcgtcatat tctgcttgag
    38701 actaacccta agatcactct tgtcctcaag ctcttttaag agaatctgaa tcccttctat
    38761 caagctcttc tgctccagtt caactggtcg caaatgcaag agcaaaaccc gcaaatcctt
    38821 ctgggcagtt tctaaaatag ctgtgacact ctgcaactgg atctgcatct tttctctatc
    38881 caatttcaaa gcctgctgac tgatacccga taaaatcatg tgggccgcaa acaactcctg
    38941 actgactgta tcgtgcaaat cccgagcaat tcgcttccgt tctttctcga tgatttcctc
    39001 ttcctgagca aggctatgat tttcagcttt ttgaagagct tctgtcaaaa ggttaagttt
    39061 acctgataag gacttgaaac tggcatccaa atctggatct gcaacctgaa ccacttcttg
    39121 ccctgccaat aaacgcttga gattagcctg catttttctt agagaaagct cttcgatccc
    39181 tcgccaaaac agggctaaga gacaggttat ggacatgctg aaaaccaaca ataaaaagac
    39241 aaatttttct gttttttcga catcgtgcaa aaagatagac cagtcaaaat caagtatttc
    39301 cagcaagctg tgggagaaaa aaaagacaaa taggaaggag gtgagagcaa taatgacata
    39361 ggcttgtttt ttcatcctct aaccacctcc acatcaccaa tcatagtggt caagaaaatc
    39421 ttgacactct tgttactctt gagatagtct tttgtttctt gatgatagtg ttcattgcgg
    39481 agggctcgct tgggctggtt gaaaaaagtc aaatccccat agagacagtt aacgctgaga
    39541 ctgacttcca catctacagg tacgatgatt ttggtcgttc ctaccatctt tctgaggata
    39601 atgacattgt catgattggt taagatgacc ctctccagat gaatagtgtc cttgcccatg
    39661 aagcgaaaga gattgatatc atcgaattgg caagtctggt agcttgaaaa atgatgaaga
    39721 tttccaaacc aacgattttt ctccttctta accgtcacga cctcttcaaa aaccaaattg
    39781 gtctgctctt tttcctggtt catcatcggg taaagaagaa agaggctata gataaccgca
    39841 acaaaaatag ctagaatcac aaaaggattg agcataacga tgaaaaagaa gagaatggtt
    39901 gccgctacta aaagaagatt atttccctct ttaccagtgt agtagcgaat caaaagcaaa
    39961 aagaggaata gtatcagcag aaaacgcgaa aaatgctctg ataccatcaa aatcagagct
    40021 cctgtcagaa gacaggcttc gataaataaa aagattttaa attttctcat aggttcatcc
    40081 tctcccttct attttatcac aattcaaaaa agtcacctca gtctgaggat ggaaaaaaag
    40141 gcgctggtta cgcctttttc atctgatcct ttgcttcttt taattttcca taaagaagat
    40201 aatctacttt ttgtagatct gctatggtgg cacagttaag ggaacacata atcaagcgta
    40261 gatctgcttt ccagccttgg acaatgccaa tcacttcttc aactgtgtag gtttcaacca
    40321 attccagaac ggttcgtgac aatcccacag ccttagcacc aaaaaccaag cacttaatca
    40381 tatccagcgg attccgaacc cctccactaa ccaagagttc gaccttatct ttccattctt
    40441 gggcattgag aagggcctgc atggtagact gaccccattg attgaggtaa tcacgctggc
    40501 cactacgacg gttttcgata taggcaaagc tggtgccacc acgacccgat aggtccactg
    40561 tacgaacacc gaattcatag gctctttcga ttgtcttggc atccattcca aagcccactt
    40621 ccttgaggac aataggaacg ggaatttgct tgatataatc tgctaaatgc gattgccagc
    40681 ttctaaactt cctttctccc tcgggcatga gtaattcctg catgacattg acatgcactt
    40741 gcaatagaac aggattcatc tcttctacag tctgaagtcc taactcgaca ggcttgtcca
    40801 atccaatatt ggttccaagg aggagattgg gatgactaga cttgacagaa aaagaatcat
    40861 ccgttggatt tttgagggct gcgctataag aacccgttac aaataaaata ccacaggatt
    40921 ccgccacctg agccagcttt tgattgattt ctcttccctt attacttcca ccagtcatgg
    40981 cattgatata aaaaggaaag tcccactttc gaccagcaaa ctctgtcgaa agatcgattt
    41041 catccagatt gtaaagaggc aaggaagaat gaatcagctc cacctcatca aagctattat
    41101 aggaactttt ctgctcaagg gcatagagga tatgctcgtc cttacgattt gtcgtcatgt
    41161 cctatccttt cttgatataa gagctcaatc cccagatcgg cccaacgatt ttttaaggtt
    41221 tcggttgatt gcgcatcaaa actcagggcg atgccacagt caccaccacc agcaccacta
    41281 ctcttggcaa cggcctgcaa atcttgactg gcttctttca actgtctaag caaaggcgtg
    41341 taaatatctg tactcaagcc ttctaaaagc ttgctggcta cttctacttg ctcgataact
    41401 ttttcggctt tcccctgctc caaggcttcg accaaagaaa ccaccgtttc ttttgaggaa
    41461 cttaaaaaat tttgattgat attttgcttg atttgctgga ccatgtgact cgatacagcc
    41521 acttccttgg tccatcccac taagaaatca cattctaaag ttggtttcac ttgtgagata
    41581 aaaaatcccc aatcacgctc cagaactgtc gccaagtttt cttcttctaa ccaagcagcc
    41641 gccttctggc gatcaaatga ctggtagaga accaaatcct ctgccacaat acaggcaagg
    41701 tcgcccatgg aaccattgtc tcctcgcttg agcaagacag cgctagtcag cttgaacaag
    41761 agattctgat caaccgaaag attatagaga gccagtaaag ccttgacaac caagacaacg
    41821 acgctgccac tagaacctag accaaacttt ttcccttctc gttccatttt gccacagatt
    41881 tttagggaaa aaggtcttaa attctgaccg cgaacagcga ggaagtctcc catcaaagca
    41941 atcgtttctt gaatcaagct gtagtcagga ttgggcctta agtccactgc gaaatcaaac
    42001 atatctgaat agatacggta gctgtcagaa aaagcaatct cagccctcat atagatggga
    42061 atatccttta tcaaagctaa ctgccctggc tctaaaatag catattcacc tgcccaatag
    42121 agttttccgc aagttttaac agcaatcatc ttgactcaaa tcctttgttt ttgacacaat
    42181 caagcgataa cgctgaccga aaatttctga caaatgctcc aagtctttct cctgacagaa
    42241 gaccttaaca ttgggaccag catccatggt aaagtagcag gcctctcctt tctcacgaag
    42301 ctggcgaaca aaggccatag cctcataaga ggcatccgtc agataagaaa aggctggact
    42361 agcagtcttt gtcgtagcat gcatagccag agcatttttc tccgttaatt ctccaatctt
    42421 ggcaaaatca ttttccttga gataaatcag catatcctga tagtccttct cagactgacg
    42481 aacccagtcg tcaaaagtcg tcgaggtttc cacacaaagt ttcatcccgt cacggctaga
    42541 gattggtttt ttcttgtcct ctagcaccaa cataatcata gctagtttca agtctgtctc
    42601 tacagggtaa atttctccac tatccttatc ccaggctcct agtggtccat aaaaactccg
    42661 agaagaagag cctgaggcaa atttggcttc ctgtgccaac tgacttctat ccaatccaag
    42721 cttgaaataa gcattacaag ccttgaccag ggcggacaaa ccactagaac ttgaggacag
    42781 gcccgctgcc gtaggcatat tgttttgagt atcgatacgg acaaagccct caccagctgg
    42841 acgataacgg tcaataatct tactcatctt ggcatgctcg acctcatttt gtagctgacc
    42901 attgatgtaa aattcgtcag ctgttacatt ggctggtaaa ggcgacaagg tcgtctctgt
    42961 atacatattt tccaaagtta gagaaatact gctagtagca ggcaccatct ctttttcttt
    43021 tttctttccc caatatttga taatagcaat atttgcgtag gaacgtactg ttacaggctc
    43081 tctatccatg tctgaacagc tcctttctct tctaatcttt ctgctagttc ttgtgcgtgc
    43141 gtcaaattgg ttaccaaggc tatgatacaa cctcctagcc caccaccgct catcttggca
    43201 cccagagcac catagctaag agccgtttca accaaaaagt ctgcctcagg gctactgact
    43261 ccaatttctt ttagatgtaa atgcgcttga ctgaggattt gtcccagtcc ttcagcatct
    43321 ttttgtgaaa tcgcaacttc tgcttgctgg gttaattctc ccaaggcatg caaaaacggt
    43381 agggcatcct tgcccttatt ttgaaccact tggatggctt cacgagtatg accataaaca
    43441 cccgtatcgg caatcaccaa ataggcggat aaatccatct caagttctgt aaatcctacg
    43501 ttcttgataa agcgaatagg ttggtcactg agacaggtct tagcatccaa accactagga
    43561 ttcatatggg caatcatctc agctcgattg accaagattt ctagtacatc atgaggcaga
    43621 tcagcctgat agtagtcaaa taccgcacga atggccgcta tgctgatagc cgctgacgaa
    43681 cccatccccc gtttctcagg gatagccgag tcaatctcac aacgaacgca ggcttctgtg
    43741 atatccaaat actccagtga ggcataaacc gccatggaca aggtatcctc ctcataaagg
    43801 cgccaaggac tctctgcaga aactacctta caggtcacct ccacctccaa aagaggcagg
    43861 gaaatggcag gataaccgta aacgaccgca tgttccccta ttaaaattat cttactatgt
    43921 gcctgaccga caccaacttt ttttgtcatt ttttcctttt actagacgaa aaaacgtctt
    43981 atttttcata caagtattaa ttctttccta tctattttat tatattttca caaaaaaagc
    44041 gattgtttcc attcacaatc gcttctttca ttattgaacc cattcgccat tataattgac
    44101 aaaatagcca tctacggtcg tattcactgc caaggcacct gagctataag cgtagtacca
    44161 tctgccattg acctggaacc aacctgtcgt catagaacga cgaaagaaac tccataccat
    44221 taagtaaaga ggaaagtcgt gagggagcat gcgccattga caacctgttt tagtgacgta
    44281 caaagtctca ttaacaagta ctcgtttcgg ccatttatag gtgcggtgtt tggagaaata
    44341 gggttcaatc ttagcccatt cttgatcgtt taaatcagta tcatatactt tgcgtgtcat
    44401 aactctagtt taacattttt tgtgaataca ggttctaaat aatcgaccac gaaaatttct
    44461 taagtggaaa acgccttatg aagtatgcta cgggaaagtt atgcacttaa tttgacaatt
    44521 caagatgtaa aaatatatac tatagtagat tgaaactaga atagtacacc
//
LOCUS       DAVKAU010000015        34403 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVKAU010000015 DAVKAU010000000
VERSION     DAVKAU010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34403
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.015"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            580..1032
                     /locus_tag="VWX48_000916"
     CDS             580..1032
                     /locus_tag="VWX48_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9171565.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1051..2388
                     /locus_tag="VWX48_000917"
     CDS             1051..2388
                     /locus_tag="VWX48_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU9171566.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSIQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2467..3351
                     /locus_tag="VWX48_000918"
     CDS             2467..3351
                     /locus_tag="VWX48_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9171567.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3351..4184
                     /locus_tag="VWX48_000919"
     CDS             3351..4184
                     /locus_tag="VWX48_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9171568.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4202..6295
                     /gene="nanB"
                     /locus_tag="VWX48_000920"
     CDS             4202..6295
                     /gene="nanB"
                     /locus_tag="VWX48_000920"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU9171569.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6308..7411
                     /locus_tag="VWX48_000921"
     CDS             6308..7411
                     /locus_tag="VWX48_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9171570.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7585..8283
                     /locus_tag="VWX48_000922"
     CDS             7585..8283
                     /locus_tag="VWX48_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU9171571.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8302..9819
                     /locus_tag="VWX48_000923"
     CDS             8302..9819
                     /locus_tag="VWX48_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9171572.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9944..11272
                     /locus_tag="VWX48_000924"
     CDS             9944..11272
                     /locus_tag="VWX48_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9171573.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11524..12390
                     /locus_tag="VWX48_000925"
     CDS             11524..12390
                     /locus_tag="VWX48_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9171574.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12406..13245
                     /locus_tag="VWX48_000926"
     CDS             12406..13245
                     /locus_tag="VWX48_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9171575.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13518..13970
                     /locus_tag="VWX48_000927"
     CDS             13518..13970
                     /locus_tag="VWX48_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9171576.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            14067..14411
                     /locus_tag="VWX48_000928"
     CDS             14067..14411
                     /locus_tag="VWX48_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171577.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIIRGIVTGLIGGHIKLGAY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGRILQIAVNVADVYGNFAYNIAAAWDA
                     HDKIPNNGRINF"
     gene            14696..15340
                     /locus_tag="VWX48_000929"
     CDS             14696..15340
                     /locus_tag="VWX48_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9171578.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15509..16426
                     /locus_tag="VWX48_000930"
     CDS             15509..16426
                     /locus_tag="VWX48_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU9171579.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16444..17328
                     /locus_tag="VWX48_000931"
     CDS             16444..17328
                     /locus_tag="VWX48_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9171580.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASMTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17344..18195)
                     /locus_tag="VWX48_000932"
     CDS             complement(17344..18195)
                     /locus_tag="VWX48_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU9171581.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18395..20452
                     /gene="pbp2b"
                     /locus_tag="VWX48_000933"
     CDS             18395..20452
                     /gene="pbp2b"
                     /locus_tag="VWX48_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU9171582.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20463..21059
                     /gene="recR"
                     /locus_tag="VWX48_000934"
     CDS             20463..21059
                     /gene="recR"
                     /locus_tag="VWX48_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU9171583.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21235..22278
                     /locus_tag="VWX48_000935"
     CDS             21235..22278
                     /locus_tag="VWX48_000935"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU9171584.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISRSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22362..23735
                     /locus_tag="VWX48_000936"
     CDS             22362..23735
                     /locus_tag="VWX48_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU9171585.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLVP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            23722..24333
                     /locus_tag="VWX48_000937"
     CDS             23722..24333
                     /locus_tag="VWX48_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9171586.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQMEQYLD"
     gene            24424..25128
                     /locus_tag="VWX48_000938"
     CDS             24424..25128
                     /locus_tag="VWX48_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU9171587.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTIYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGIFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25347..26720
                     /gene="ftsA"
                     /locus_tag="VWX48_000939"
     CDS             25347..26720
                     /gene="ftsA"
                     /locus_tag="VWX48_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU9171588.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRTGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26737..27996
                     /gene="ftsZ"
                     /locus_tag="VWX48_000940"
     CDS             26737..27996
                     /gene="ftsZ"
                     /locus_tag="VWX48_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU9171589.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28001..28672
                     /locus_tag="VWX48_000941"
     CDS             28001..28672
                     /locus_tag="VWX48_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU9171590.1"
                     /translation="MNVKENTELVFREVAEASLSANRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELMEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28682..29221
                     /locus_tag="VWX48_000942"
     CDS             28682..29221
                     /locus_tag="VWX48_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU9171591.1"
                     /translation="MSLKDRFDRFIDYFTENEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29221..29484
                     /locus_tag="VWX48_000943"
     CDS             29221..29484
                     /locus_tag="VWX48_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU9171592.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSIWVAIVLVRFLGENLVRFLAMIG"
     gene            29481..30266
                     /locus_tag="VWX48_000944"
     CDS             29481..30266
                     /locus_tag="VWX48_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU9171593.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30275..31009
                     /gene="divIVA"
                     /locus_tag="VWX48_000945"
     CDS             30275..31009
                     /gene="divIVA"
                     /locus_tag="VWX48_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001123193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU9171594.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVHDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DLLRPTATYLQTSDEAFKEVVSKVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELAEFEAQIKQEVEAPTCSESSG"
     gene            31409..34201
                     /locus_tag="VWX48_000946"
     CDS             31409..34201
                     /locus_tag="VWX48_000946"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU9171595.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10590 a         6092 c         7478 g        10243 t
ORIGIN      
        1 atactctaat tgaaaacggt aacaaaacta atttagagaa tgaaatatag agtatttctc
       61 tcttaaaagt ttttggtgaa acgagatgta gaaaggagat ttagccaaag agtctattag
      121 tgctagaata atagattaga attattttag aaaaacgaag tgagcagctt ataaattcaa
      181 gtccccaaat agattcatac tagtatcttt tgcaaaaaat aaagggcgac ttccttcatg
      241 aatatcaatt tcatctataa ggaaggtagc taattgaact aacttattta ttctgtttgt
      301 cgctagaaaa atcagacctc cttgtgaaga ttgaggagat acttaatgaa aatcaaagaa
      361 gaaactagca agctagtagc agattgccca aaacaccgct ttgaggttgt agataagact
      421 gacctatata atccaaggtg aagcgactgt ggtttgaaga gattttcaaa gagtataggc
      481 tagagagtag tgtttttatg tccttctagt agaaaatgct agacagaaga atggggaact
      541 tggataggaa aaatagattg agaaaggagg ttagaagaga tgattattac aaaaattagc
      601 cgtttaggaa cttatgtggg agtaaatcca cattttgcaa cattaataga ttttctagaa
      661 aaaacaggac tagaaaattt aacagaaggt tcgattgcta tcgatggtaa tcgattgttt
      721 gggaattgct ttacttatct agcagatggt caagcagggg ctttctttga aacacaccaa
      781 aaatatttgg atattcattt agttttggaa aacgaagaag ccatggctgt tacatcgccg
      841 gaaaatgtaa gcgttaccca agaatatgat gaagagaaag atattgaatt atacacaggg
      901 aaagtggaac agttggttca tttgagagct ggtgaatgcc tcatcacttt tccagaagat
      961 ttacatcaac ccaaggttcg tataaatgat gaacctgtga aaaaagttgt ctttaaagtt
     1021 gcgatttctt aatgtagaaa gagaagaacg atgaaaaaaa tgagaaagtt tttatgtcta
     1081 gctggaattg cgctagcggc tgttgccttg gtagcttgtt caggaaaaaa agaagctaca
     1141 actagtactg aaccaccaac agaattatct ggtgagatta caatgtggca ctcctttact
     1201 caaggacccc gtttagaaag tattcaaaaa tcagcagatg ctttcatgca aaagcatcca
     1261 aaaacgaaaa tcaagattga aacattttct tggaatgact tctatactaa atggactaca
     1321 ggtttagcaa atggaaatgt gccagatatc agtacagctc ttcctaacca agtaatggaa
     1381 atggtcaact cagatgcttt ggtgccgcta aatgattcta tcaagcgtat tggacaagat
     1441 aaatttaacg aaactgcctt aaatgaggca aaaatcggag atgattacta ctctgttcct
     1501 ctttattcac atgcacaagt catgtgggtt agaacagatt tgttaaaaga acataatatt
     1561 gaggttccta aaacttggga tcaactctat gaagcttcta aaaaattgaa agaagctgga
     1621 gtttatggct tgtctgttcc gtttggaaca aatgacttaa tggcaacacg tttcttgaac
     1681 ttctacgtac gtagtggtgg aggaagcctc ttaacaaaag atcttaaagc agacttgaca
     1741 agccaacttg ctcaagatgg tattaaatac tgggttaaat tgtataaaga aatctcacct
     1801 caagattctt tgaattttaa tgtccttcaa caagctacct tgttctatca aggaaaaaca
     1861 gcatttgact ttaactctgg cttccatatc ggaggaatta atgccaacag tcctcaattg
     1921 attgattcga ttgatgctta tcctattcca aaaatcaaag agtctgataa agaccaagga
     1981 attgaaacct caaacattcc aatggttgtt tggaaaaatt caaaacatcc agaagttgct
     2041 aaagcattct tagaagcact ttataatgaa gaagactacg ttaaattcct tgattcaact
     2101 ccagtaggta tgttgccaac tattaagggg attagcgatt ctgcagccta taaagaaaat
     2161 gaaactcgta agaagtttaa acatgctgaa gaagtaatta ctgaagctgt taaaaaaggt
     2221 actgctattg gttatgaaaa tggaccaagt atacaagctg gtatgttgac taaccaacac
     2281 attattgaac aaatgttcca agatatcatt acaaatggaa cagatcctat gaaagcagca
     2341 aaagaagcag aaaaacaatt aaacgattta tttgaggctg ttcagtagat gtaaaagact
     2401 agaaaatagg tgggctagtg agctgaaaag ctctagccca attttgtaaa agaagggaga
     2461 aggagaatgg ttaaagaacg taatttaact cgctggatat ttgttttgcc agctatgatt
     2521 atcgtaggat tactctttgt ttatccgttt ttctcgagta ttttttatag ctttaccaat
     2581 aagcatttga ttatgcctaa ttataaattt gttggtttgg ctaactataa agctgtgcta
     2641 tcagatccca acttctttaa tgcgttcttt aattcaatta agtggaccat tttctcatta
     2701 gttggtcaag ttttagtagg gtttgtattg gctttagctc ttcacagagt acgccacttc
     2761 aagaaattat ataggacctt attgattgtt ccttgggcat ttcctaccat cgttattgcc
     2821 ttctcttggc agtggattct aaacggggtt tatggctact tacctaatct aatcgtaaaa
     2881 ttaggtttaa tggaacatac acctgcattt ttgacagata gtacatgggc attcctatgt
     2941 ttggtgttta tcaacatttg gtttggagca ccaatgatta tggttaatgt gctttcagct
     3001 ttgcaaacag taccagaaga acaatttgag gctgctaaga tagatggtgc ttcaagttgg
     3061 caggtgttca agtttatcgt ctttccacat attaaagtgg ttgtaggact tctagttgtt
     3121 ttgagaactg tatggatctt taataacttt gacattatct acctcattac tggtggtgga
     3181 ccagccaatg ctacaacgac gcttccaatt tttgcttaca acctgggctg gggaactaaa
     3241 ttgttgggtc gtgcttcagc agttacagta ttgctcttta tcttcttggt ggcgatttgc
     3301 tttatctact ttgctatcat cagtaagtgg gaaaaggagg gtagaaaata atgaagaaga
     3361 aatccagtat ttatttagat attctctcac atgtactttt agttggtgcg accatcgttg
     3421 cagttttccc attggtatgg attatcatat cttctgtcaa agggaaaggg gaattaactc
     3481 agtatccaac acgattttgg cctgaacagt ttacattaga ttatttcact catgttatca
     3541 acgatttgca cttcattgat aacattcgaa acagtttaat cattgccttg gctacaaccc
     3601 ttattgcgat tattatttct gctatggcag cctatggtat tgttcgattc tttcctaaat
     3661 tgggagcaat catgtcgaga ctactcgtca ttacctacat tttcccacca attttgttag
     3721 caattcccta ttcaattgcc attgctaaag ttgggttaac aaatagttta tttggcttga
     3781 tgatggttta tctatctttt agtgttccat atgcagtttg gctcttagtt ggatttttcc
     3841 aaacagttcc aattggaatt gaagaagcgg ctagaattga tggtgcaaat aaatttgtta
     3901 cgttttataa agttgtgcta ccgattgtag caccaggtat tgtagcaaca gctatttata
     3961 catttatcaa tgcttggaat gaattcctgt atgccttgat tttgattaac aatacaggaa
     4021 agatgacagt agcagtagcc cttcgttcac ttaatggttc agaaatacta gactggggag
     4081 atatgatggc agcgtctgtt attgtagttc ttccatcaat tattttcttc tctatcatcc
     4141 aaaataagat tgcaagtgga ttatcagaag gatctgtgaa gtagacgaaa gaaggaaaaa
     4201 aatgaataaa agaggtcttt attcaaaact aggaatttct gttgtaggca ttagtctttt
     4261 aatgggagtc cccactttga ttcatgcgaa tgaattaaac tatggtcaac tgtccatatc
     4321 tcctattttt caaggaggct catatcaact gaacaataag agtatagata tcagcccttt
     4381 gttattagat aaattgtctg gagagagtca gacagtagta atgaaattta aagcagataa
     4441 accaaactct cttcaagctt tgtttggcct atctaatagt aaagcaggct ttaaaaataa
     4501 ttacttttca attttcatga gagattctgg tgagataggt gtagaaataa gagacgccca
     4561 aaagggaata aattatttat tttctagacc agcttcatta tggggaaagc ataaaggaca
     4621 ggcagttgaa aatacactag tatttgtatc tgattctaaa gataaaacat acacaatgta
     4681 tgttaatgga atagaagtgt tctctgaaac agttgataca tttttgccaa tttcaaatat
     4741 aaatggtata gataaggcaa cactaggagc tgttaatcgt gaaggtaagg aacattacct
     4801 cgcaaaagga agtattgatg aaatcagtct atttaacaaa gcaattagtg atcaggaagt
     4861 ttcaaatatt cccttgtcaa atccatttca gttaattttc caatcaggag attctactca
     4921 agctaactat tttagaatac cgacactata tacattaagt agtggaagag ttctatcaag
     4981 tattgatgca cgttatggtg ggactcatga ttctaaaagt aagattaata ttgccacttc
     5041 ttatagtgat gataatggga aaacgtggag tgagccaatt tttgctatga agtttaatga
     5101 ctatgaggag cagttagttt actggccacg agataataaa ttaaagaata gtcaaattag
     5161 tggaagtgct tcattcatag attcatccat tgttgaagat aaaaaatctg ggaaaacgat
     5221 attactagct gatgttatgc ctgcgggtat tggaaataat aatgcaaata aagccgactc
     5281 aggttttaaa gaaataaatg gtcattatta tttaaaacta aagaagaatg gagataacga
     5341 tttccgttat acagttagag aaaatggtgt cgtttatgat gaaacaacta ataaacctac
     5401 aaattatact ataaatgata agtatgaagt tttggaggga ggaaagtctt taacagtcga
     5461 acaatattcg gttgattttg atagtggctc tttaagagaa aaacataatg gaaaacaggt
     5521 ccctatgaat gttttctaca aagattcgtt atttaaagtg actcctacta attatatagc
     5581 aatgacaact agtcagaata gaggagagag ttgggaacaa tttaagttgt tgcctccgtt
     5641 cttaggagaa aaacataatg gaacttactt atgtcccgga caaggtttag cattaaaatc
     5701 aagtaacaga ttgatttttg caacatatac tagtggagaa ctaacctatc tcatttctga
     5761 tgatagtggt caaacatgga agaaatcctc agcttcaatt ccgtttgaaa atgcaacagc
     5821 agaagcacaa atggttgaac tgagagatgg tgtgattaga acattcttta gaaccactac
     5881 aggtaagata gcttatatga ctagtagaga ttctggagaa acatggtcgg aagtttcgta
     5941 tattgatgga atccaacaaa cttcatatgg cacacaagta tctgcaatta aatactctca
     6001 attaattgat ggaaaagaag cagtcatttt gagtacacca aattctagaa gtggccgtaa
     6061 gggaggtcaa ttagttgtcg gtttagtcaa taaagaagat gatagtattg attggaaata
     6121 ccactatgat attgatttgc cttcgtatgg ttatgcctat tctgcgatta cagaattgcc
     6181 aaatcatcac ataggtgtac tgtttgaaaa atatgattcg tggtcgagaa atgaattgca
     6241 tttaagcaat gtagttcagt atatagattt ggaaattaat gatttaacaa aataaaggag
     6301 aaaaaacatg gttaaatacg gtgttgttgg agcagggtat tttggagctg aattggctcg
     6361 ctacatgcaa aagaatgatg gagcagagat tactcttctc tatgatccag ataatgcaga
     6421 ggcgattgca gaagaattgg gagcaaaagt agcaagttcc ttagatgagt tggtttctag
     6481 cgatgaagta gattgtgtta tcgtcgcaac tccaaataat cttcataagg aaccggttat
     6541 taaggctgca cagcatggta aaaatgtttt ctgtgaaaaa ccaattgcgc tttcttatca
     6601 agattgtcgc gagatggtag atgcgtgtaa agaaaacaat gtaaccttta tggcaggaca
     6661 tattatgaat ttctttaatg gtgttcatca tgcaaaagaa ctcattaatc aaggagttat
     6721 cggagacgtt ctatattgtc atacagctcg taatggttgg gaagaacaac aaccgtcagt
     6781 atcatggaaa aaaattcgtg aaaaatcagg tggtcacttg tatcaccaca tccatgaatt
     6841 ggattgcgtt caattcctta tggggggcat gcctgaaact gtaaccatga caggtggaaa
     6901 tgtggcccat gaaggtgaac atttcggtga tgaagatgat atgatttttg tcaatatgga
     6961 attttctaat aagcgttttg ctttgttaga atggggttca gcttatcgtt ggggtgaaca
     7021 ttatgtctta atccaaggaa gcaaaggtgc catccgctta gacttattca actgtaaagg
     7081 aactcttaag ctagatgggc aagaaagcta tttcttgatt cacgaatcgc aagaagaaga
     7141 tgatgatcgg actcgtatct atcatagtac agagatggat ggagcaattg cttatggtaa
     7201 accaggtaaa cgtactccat tatggctatc atctgtcatt gataaagaaa tgcgctatct
     7261 gcatgagatt atggaaggag ctccagtatc agaagaattt gcaaaacttt tgacaggtga
     7321 agctgcccta gaagcaattg ctactgcaga tgcttgtacc cagtctatgt ttgaagatcg
     7381 caaagtaaaa ttgtcagaaa ttgtaaaata aattttggta ttctcctatt tataggtcga
     7441 cttgctcctc tgaaagtact tttagaggag ctgtttgact ttgctagttt ttgaaactga
     7501 aatctattat actacaaact attgaaagcg ttttaatttt aaggtataat aatctcatag
     7561 aaataaagaa aaggaggaaa gaggatgcca cagattagca aagaagcctt gattgagcaa
     7621 atcaaagatg gaatcatcgt ttcttgtcag gctcttcctc atgaaccgct ttatacagaa
     7681 gcgggagggg tgattccctt gctggtcaaa gcggctgagc aaggtggagc agtcggtatc
     7741 cgagcaaaca gtgttcgcga tatcaaggaa attaaggagg tcactaaact tccaatcatt
     7801 gggattatca aacgtgatta tccacctcag gaacccttca tcacggctac tatgaaagaa
     7861 gttgatgaat tggcagaact ggacatcgag gtgattgctc tggattgtac caagcgtgaa
     7921 cgctacgatg gtttggaaat tcaagagttc attcgtcagg ttaaggagaa atatcctaat
     7981 cagcttttga tggctgatac tagtatcttc gaagaagggc tagcagctgt agaagcagga
     8041 attgactttg tcggaacaac cttatcaggc tacacatcct acagtccaaa agtagacggt
     8101 ccagattttg aattgattaa gaaactctgt gatgccggtg tagatgtcat tgcagaagga
     8161 aaaattcata caccagaaca agccaaacaa atccttgaat atggagtgcg aggcatcgtt
     8221 gttggtggcg ccattactag accaaaagag attacagaac gcttcgttgc tagtcttaaa
     8281 taagatgtga gggggagttt tatgtttaaa gttttacaaa aagttggaaa agcttttatg
     8341 ttacctatag ctatacttcc tgcagcaggt ctacttttgg ggattggtgg tgcactttca
     8401 aacccaacca cgatagcaac ttatccaata ctagacaata gtatttttca atcaatattc
     8461 caagtaatga gctctgcagg agaggttgta ttcagtaatt tgtcactact tctctgtgtg
     8521 ggattatgta ttggcttagc gaaacgagat aaaggaaccg ctgcgttagc aggagtaact
     8581 ggttacttag ttatgactgc aacgatcaaa gctttagtaa aactttttat ggcagaagga
     8641 tctgcaattg atactggagt tattggagca ttagttgtcg gaatagttgc cgtatatttg
     8701 cacaaccgat ataacaatat tcaattacct tccgctttag gattctttgg aggttcacgc
     8761 ttcgttccta ttgttacatc gttctcttct atcttgattg gctttgtctt ctttgttatt
     8821 tggccacctt tccaacaact tcttgtttct acaggtggat atatttctca ggcgggtcca
     8881 attggaactt ttctatatgg atttttaatg agactttctg gagcagtagg cttacatcat
     8941 ataatttacc ctatgttttg gtatactgaa cttggtggtg ttgaaactgt tgcaggacaa
     9001 acagtggttg gagctcaaaa aatatttttt gctcaattag ccgatctggc ccattctgga
     9061 ttatttacag aaggaacaag gttttttgca ggtcgtttct caacaatgat gttcggttta
     9121 ccggctgcct gtttagcgat gtaccatagt gttcctaaaa atcgtcgtaa aaaatacgcg
     9181 ggtttgtttt ttggagttgc tttaacatct tttattaccg gtattacaga accaattgaa
     9241 tttatgtttc tattcgtcag tccggttcta tatgttgttc acgcattcct tgatggtgtt
     9301 agcttcttta ttgcagacgt cttaaatatt tcaataggaa acacattttc aggaggtgta
     9361 atcgatttca ctttatttgg aattttgcag gggaacgcta agacgaattg ggttcttcag
     9421 attccatttg gacttatttg gagtgttttg tattatatta tttttagatg gttcattact
     9481 caattcaacg ttctaacgcc aggacgagga gaagaagtag attctaaaga aatttctgaa
     9541 tccgcagatt caacttcaaa tactgcagat tatttaaaac aggatagcct acaaattatc
     9601 agagccttgg gtggatcaaa taatatagaa gatgtagatg cttgtgtgac acgtttacgt
     9661 gtagctgtaa aagaagttaa tcaagttgat aaagcacttt taaaacaaat tggtgcagtt
     9721 gatgtcttag aagtgaaggg tggcattcaa gcaatctatg gagcaaaagc aatcttatat
     9781 aaaaatagta ttaatgaaat tttaggtgta gatgattaag tacttactga cttaataaaa
     9841 aacagaggag agtgatggat gagtaggatg aaatgaaatc gcatacaaga aataaagaac
     9901 tcattatcca agttggatac gcttattaca taggagaata caaatgaaat ttagaaaatt
     9961 agcttgtaca gtacttgcgg gtgctgcggt tcttggtctt gctgcttgtg gcaattctgg
    10021 cggaagtaaa gatgctgcca aatcaggtgg tgacggtgcc aaaacagaaa tcacttggtg
    10081 ggcattccca gtatttaccc aagaaaaaac tggtgacggt gttggaactt atgaaaaatc
    10141 aatcatcgaa gcgtttgaaa aagcaaaccc agatataaaa gtgaaattgg aaaccatcga
    10201 cttcaagtca ggtcctgaaa aaatcacaac agccatcgaa gcaggaacag ctccagacgt
    10261 actctttgat gcaccaggac gtatcatcca atacggtaaa aacggtaaat tggctgagtt
    10321 gaatgacctc ttcacagatg aatttgttaa agatgtcaac aatgaaaaca tcgtacaagc
    10381 aagtaaagct ggagacaagg cttatatgta tccgattagt tctgccccat tctacatggc
    10441 aatgaacaag aaaatgttag aagatgctgg agtagcaaac cttgtaaaag aaggttggac
    10501 aactgatgat tttgaaaaag tattgaaagc acttaaagac aagggttaca caccaggttc
    10561 attgttcagt tctggtcaag ggggagacca aggaacacgt gcctttatct ctaaccttta
    10621 tagcggttct gtaacagatg aaaaagttag caaatataca actgatgatc ctaaattcgt
    10681 caaaggtctt gaaaaagcaa ctagctggat taaagacaat ttgatcaata atggttcaca
    10741 atttgacggt ggggcagata tccaaaactt tgccaacggt caaacatctt acacaatcct
    10801 ttgggcacca gctcaaaatg gtatccaagc taaactttta gaagcaagta aggtagaagt
    10861 ggtagaagta ccattcccat cagacgaagg taagccagct cttgaatatc ttgtaaacgg
    10921 gtttgcagta ttcaacaata aagacgacaa gaaagtcgct gcatctaaga aattcatcca
    10981 gtttatcgca gatgacaaag agtggggacc taaagacgta gttcgtacag gtgctttccc
    11041 agtccgtact tcatttggaa aactttatga agacaaacgc atggaaacaa tcagcggctg
    11101 gactcaatac tactcaccat actacaacac tattgatgga tttgctgaaa tgagaacact
    11161 ttggttccca atgttgcaat ctgtatcaaa tggtgacgaa aaaccagcag atgctttgaa
    11221 agccttcact gaaaaagcga acgaaacaat caaaaaagct atgaaacaat agtccttagt
    11281 tattctataa aaagtagttt tttaaagaac ctaagagtgt ataccccctt ttccctctac
    11341 acagatagtg taagaaaagg gggcttttgt ttaaaatgta agaaactgtc acgaaattaa
    11401 aatgaagttc ttacataagc gaaccataaa aaatttcatt ttgattttaa aacagttcaa
    11461 gaaagtcaaa aaattattct atttgaaaga gaggtgccga ctgtgaaagt caataaaatc
    11521 cgtatgcggg aaacagtgat ttcctatgct ttcctagcac cagtattatt cttctttgtc
    11581 atctttgtgt tggctccgat ggtgatgggc ttcattacaa gtttctttaa ctactcaatg
    11641 actaaatttg agtttgtagg cttggataac tatatccgta tgtttaaaga tcctgtcttt
    11701 acaaaatctc tgattaacac agttattttg gttattggat ctgtaccagt tgttgttcta
    11761 ttctcactct ttgtagcatc tcagacctat catcaaaatg tcattgccag atccttctac
    11821 cgtttcgtct tcttccttcc tgttgtaacg ggtagtgttg ccgtgacagt tgtttggaaa
    11881 tggatttatg acccactatc agggattcta aactttgtcc ttaagtcaag ccacatcatc
    11941 agccaaaaca tttcttggtt gggagataaa aactgggcat tgatggcgat tatgattatt
    12001 ctcttgacca cttcagttgg tcagcccatc atcctttata tcgctgccat ggggaatatt
    12061 gacaattcac tggttgaagc ggcgcgtgtt gatggtgcaa ctgagtttca agttttttgg
    12121 aagattaaat ggccaagcct tcttccaaca actctttata ttgcaatcat cacaacaatt
    12181 aactcattcc agtgtttcgc cttgattcag cttttgacat ctggtggtcc aaactactca
    12241 acaagtacct tgatgtacta cctttacgaa aaagccttcc aattgacaga atacggctat
    12301 gccaacacaa ttggtgtctt cttggcagtc atgattgcta tcgtaagctt tgttcaattt
    12361 aaagtacttg gaaacgacgt agaatactaa agaaaggaga cagctatgca atctacagaa
    12421 aaaaaaccat taacagcctt tactgttatt tcaacaatca ttttgctctt gttgactgtg
    12481 ctgttcatct ttccattcta ctggattttg acaggggcat tcaaatcaca acctgataca
    12541 attgttattc ctcctcagtg gttccctaaa atgccaacca tggaaaactt ccaacaactc
    12601 atggtgcaga accctgcctt gcaatggatg tggaactcag tatttatctc attggtaacc
    12661 atgttcttag tttgtgcaac ctcatctcta gcaggttatg tattggctaa aaaacgtttc
    12721 tatggtcaac gcattctatt tgctatcttt atcgctgcta tggcgcttcc aaaacaagtt
    12781 gtccttgtac cattggtacg tatcgtcaac ttcatgggaa tccacgatac tctctgggca
    12841 gttatcttgc ctttgattgg atggccattc ggtgtcttcc tcatgaaaca gttcagtgaa
    12901 aatatcccta cagagttgct tgaatcagct aaaatcgacg gttgtggtga gattcgtacc
    12961 ttctggagtg tagccttccc gattgtgaaa ccagggtttg cagcccttgc aatctttacc
    13021 ttcatcaata cttggaatga ctacttcatg cagttggtaa tgttgacttc acgtaacaat
    13081 ttgaccatct cacttggggt tgcgaccatg caggctgaaa tggcaaccaa ctatggtttg
    13141 attatggcag gagctgccct tgctgctgtt ccaatcgtca cagtcttcct agtcttccaa
    13201 aaatccttca cacagggtat tactatggga gcggtcaaag gataatactc tgcgaaaatc
    13261 gaatgcaaac tacgtcagct tcaccttgcc atacttaagt attgcctgtg gttagcttcc
    13321 tagtttgttc ttcaattttc attgagtata ggaaaatcaa tctatcaaga tacagaagta
    13381 tattttatag atttagagaa tatagaagtt ataagtgtct acaaaatgga gggtatgcag
    13441 ttactttatg aagttttgtc agacacttat aaacttaaga atggttttag ttaactatca
    13501 gaaacgaagg aaagagtatg atttttgacg atttgaaaaa catcaccttt tacaaaggga
    13561 ttcatcccaa tttagacaag gctatcgact atctctacca acatcgtaaa gattcattcg
    13621 aattaggaaa gtatgagatt gatggagata aagtctttct agttgttcag gaaaatgtcc
    13681 tcaatcaagt tgagaataat caatttgaac accataagaa ctatgcagat ttgcatttgc
    13741 tgatagaagg gcatgaatat tcgagctacg gttcacgtat caaagacgag gcagtagcat
    13801 tcgacgaagc gagtgacatt ggctttgttc attgtcatga acactaccca ctcttgttgg
    13861 gttatcacaa ttttgcgatt ttcttcccag gtgagccaca tcagccaact ggttatgcag
    13921 gcatggaaga aaaggttcgg aaatatctct ttaaaatttt gattgattaa aaataggatg
    13981 aattgttttt ttgtaaagct ttgacaatac tctaccatga aattgatctt tgtgaggtag
    14041 agaaatgaga ataaaatatt taaaaattgg tatcttctaa gcatgctgca agagctagtt
    14101 tcttagatgg acagggaatt acagttgatg agatgtcctg gataattagg ggcattgtga
    14161 ctggattgat tggcggacac ataaaattag gtgcttatgc agctaagtat ggtattagta
    14221 tagcacgatc gatcttaagt agggcagctg caactgcagc agcaagagta ggattactga
    14281 ccaagatttc tggaaggatt ttacaaatag ctgtgaatgt agctgatgta tatggtaatt
    14341 ttgcctacaa tattgctgca gcttgggatg cacatgataa aatccctaac aatggtcgta
    14401 taaactttta aaatgcgaga atgaaagcac tttgtatttt ttattgtata tgttagcttg
    14461 gacagtgctt gcaatgataa tccgtggagg aataaatgga tttgatgaac acacttggcg
    14521 taatatttta gctagtgcgt tgtcctcgct atatatacat tatatatcca tagataaaaa
    14581 tagaaaaagt ccaaaagaaa aaagaaaaaa tagatttgtt catggtaggg acttatgaaa
    14641 gctttactga caaaaaagaa aacagtttac aaagaaaaat gatggaggag caaacatggc
    14701 acaaaaagga gtaagcctta tcaaggcagc atttgataca gataactttc tcatgcgttt
    14761 tagtgagaag gtcttggaca tcgtgacagc caatcttctt tttgtcgtct cttgtttacc
    14821 catcgtgacg attggagtgg ctaaaatcag cctctacgag accatgttcg aagttaagaa
    14881 gagcagacgg gtgcctgttt ttaaaatcta tctaagatct ttcaagcaaa atctgaaact
    14941 aggtcttcag ctgggtttaa tggagttagg aattgtgttt cttacccttt cagatctcta
    15001 tcttttctgg ggtcaaacag ctctgccctt ccaattgctg aaagccattt gtttaggtat
    15061 tctgattttt cttactatcg tgatgctggc tagttaccct atcgcggcac gttatgacct
    15121 atcttggaaa gaaattcttc aaaaaggatt gatgttggct agttttaact ttccttggtt
    15181 cttcctcatg ttagccattc ttgtcctcat tgtgatggtt ctttatctgt ccgccttcag
    15241 tctactctta ggtggctcag tcttcctact ttttgggttt ggactattgg tctttatcca
    15301 gactggattg atggagaaaa ttttcgcaaa ataccaatag gagctttatt tctgaaacta
    15361 ctttcaaagg ctccaaacgc tattctataa gcgagaaact aaaatctaag tgtctataag
    15421 atattgaaag ccttttcggt aaagtgtata ctaaagaagt aaagaaaaat ctgctttagc
    15481 agaaaataaa aataatagga gaaaatctat gtcagatttg aaaaaatacg aaggtgtcat
    15541 tccagccttc tacgcatgtt atgatgatca aggagaagta agcccagaac gtacgcgtgc
    15601 cttggttcaa tacttcattg ataaaggtgt tcaaggtctt tatgtcaatg gttcttctgg
    15661 tgaatgtatc taccaaagcg ttgaagatcg caagttgatt ttggaagaag tcatggcggt
    15721 agccaaaggt aaattgacca ttattgccca tgttgcttgc aataatacta aagatagtat
    15781 ggaacttgct cgccatgctg aaagcttggg agtagatgct attgcaacga ttccaccaat
    15841 ttatttccgc ttgccagaat actcagttgc caaatactgg aacgatatca gttctgcagc
    15901 tccaaacaca gactacgtga tttacaacat tcctcaattg gcaggggttg ctttgactcc
    15961 aagcctttac acagaaatgt tgaaaaatcc tcgtgttatc ggtgtgaaga actcttctat
    16021 gccagttcaa gatatccaaa cctttgtcag ccttggtgga gaagaccata tcgtctttaa
    16081 tggtcctgat gagcagttcc taggaggacg cctcatgggg gctagggctg gtatcggtgg
    16141 tacttatggt gctatgccag aactcttctt gaaactcaat cagttgattg cggataagga
    16201 cctagaaaca gcgcgtgaat tgcagtatgc tatcaacgca atcattggta aactcacttc
    16261 tgctcatgga aatatgtacg gtgtcatcaa agaagtcttg aaaatcaatg aaggcttgaa
    16321 tattggatct gttcgttcac cattgacacc agtgactgaa gaagatcgtc cagttgtaga
    16381 agcggctgct gccttgattc gtgaaaccaa ggagcgcttc ctctaatcta aaaggaggta
    16441 tttatgacat attacgttgc aattgatatc ggtggaacca acatcaagta tggtttggtt
    16501 gatcaagagg ggcaacttct tgaatcgcat gaaatgccaa ctgaggcgca taagggtgga
    16561 cctcatatct tacaaaagac caaagatatc gttgctagtt atttagaaaa aggcccagta
    16621 gcaggtgttg ccatatcttc tgctgggatg gtggatccgg ataagggtga gattttctat
    16681 gctgggccgc aaatccctaa ctacgcaggc acccagttca aaaaggaaat cgaagaaagc
    16741 tttactattc cttgtgagat tgaaaatgat gtcaactgtg caggtcttgc tgaggcagta
    16801 tctggttcag gcaagggagc aagtatgaca ctttgcttga ccattggaac cggtatcggt
    16861 ggttgtttga ttatggatag gaaagtcttc catggtttta gtaattcagc ctgtgaagtc
    16921 gggtatatgc atatgcagga tggagctttt caggatctcg cttctacaac agctttagtg
    16981 aaatatgtag ctgaagccca tggagaagat gttgatcagt ggaatggccg acgtatcttt
    17041 aaggaagcta ctgaaggaaa caaaatctgc atggaaggca ttgaccgtat ggttgactat
    17101 ctaggaaaag gtctggcaaa tatttgctac gttgccaatc cagaagtggt tattcttggt
    17161 ggtggtatca tggggcaaga ggctatcctc aaacctaaga tccgcacagc cttgaaagag
    17221 gctttggtac caagtttagc agaaaaaaca cgattagaat ttgcccatca ccaaaataca
    17281 gcagggatgt tgggtgcata ttatcatttt aagacaaaac aatcctagtt tggctcagcc
    17341 aaactaggat tttcttacac gtttttgtct acgatagccg ttgagttttt tattttccca
    17401 gtagctatta aagatttttt ccttgctttc gcgattgatt tccaaaaagt aggcataaat
    17461 caaatcgata aagaagagca taggaagttg agcggatatt cgttggatat aggagggttg
    17521 gctgtgggtg gctacaagaa cagtctctgt ataggtctgg ctatctttat tgggaacact
    17581 tgtaaagagt acagtctttg cccccatctc cttggcatct aatagactat ctaaaataga
    17641 aggagttgag cctgaaagtg agaagcccag tactagacaa ttttcatcca tgatgctggt
    17701 tgtccaggca aagccgtctt ggtctgtcaa agcttcgcag accacaccta gtcgcataaa
    17761 acgtaatttc atttcacggg cgacgaggcc agaactccct gttccaaaga agtagatacg
    17821 ctcagcatct tcgattagct gggcaattcg ctctagttgg atttcgtcaa tcaagtcttg
    17881 tgtttgttcc ctcatattgc tataacttct gaggactcgt ttggtcagtg gactgtgctt
    17941 ggagacttgg ttggcttgat tttctgcctg atgttggtat tggaaaataa attctcggta
    18001 gccagtaaag ccacactttt tagcaaagcg ggtcaaagca gcttgagaaa tatgtaattt
    18061 ttgggtgact tgttgagaag ataaatcatc tgtaatcgtt tcagcttgca aaaaatagcg
    18121 agcgatttct tgctctaggt ctgtcatttc ttcaaaatgt gaatcaatga tagttgcgat
    18181 atctggtttg tccataggga aagctccttt acatgagtca tactggaaga ctagatcagg
    18241 gaatagtcac acttcattat aacacataat ataaggatag ataaataaaa acgcatctct
    18301 gttttaaaaa cgaaaaaatc gaaaaagctt ctctcttttc cataattttc tactcaaatt
    18361 gtggtacaat taagagtaag attttaagtt agaaatgaga ctgatttgta tgagaaaatt
    18421 taacagccat tcgattccga ttcggcttaa tttattgttt tcaatcgtca ttttactctt
    18481 tatgaccatt attggtcgtt tgttgtatat gcaggttttg aacaaggatt tttacgaaaa
    18541 aaagctagcc tcagctagtc agaccaagat tacaagcagt tcagcccgtg gggaaattta
    18601 tgatgctagt ggaaaacctt tggtagaaaa tacgttaaag caggttgttt cctttacgcg
    18661 tagcaataaa atgacggcta cagacttaaa agaaacagct aaaaagttac tgacttatgt
    18721 gagcatcagt tctccaaatt tgacagaacg ccagctggcg gattactatt tggctgatcc
    18781 tgaaatctat aaaaaaatag tggaagctct cccaagtgag aaacgcttgg attcagatgg
    18841 caatcgtcta tccgaatcag aactgtataa caatgcggtc gatagtgtac aaacgagtca
    18901 actaaattat acagaggatg aaaagaaaga aatctatctt tttagtcagt taaatgctgt
    18961 tggaaacttt gcgacaggaa ccattgcgac agatcctcta aatgattctc aggtggctgt
    19021 tattgcctct atttcaaagg agatgcctgg cattagtatt tctacttctt gggatagaaa
    19081 ggttttggaa acttcccttt cttctatagt tgggagtgta tccagtgaaa aagctggtct
    19141 cccagcggaa gaagcagaag cctatcttaa aaaaggctat tctctaaatg atcgtgtagg
    19201 aacctcctat ttggaaaagc aatatgaaga gaccttacaa ggaaaacgct cggtaaaaga
    19261 aatccatctg gataaatatg gaaatatgga aagcgtggat acaattgagg aaggtagtaa
    19321 gggaaacaat atcaaactga ccattgattt ggccttccaa gatagcgtgg atgctttact
    19381 gaaaagttat ttcaattccg agctagaaaa tggtggagcc aagtattctg aaggtgtcta
    19441 tgcagtcgcc cttaacccaa aaacaggtgc ggttttgtct atgtcaggga ttaaacatga
    19501 cttgaaaacg ggagagttga cgcctgattc cttgggaacg gtaaccaatg tctttgttcc
    19561 aggttcggtt gtcaaggcgg cgaccatcag ctcaggttgg gaaaatggag tcttgtcagg
    19621 aaaccagacc ttgacagacc agtccattgt cttccaaggt tcagctccca tcaattcttg
    19681 gtatactcag gcttacggtt cattccctat cacagcggtc caagctctgg agtattcatc
    19741 aaatacctat atggtccaaa cagccttagg tcttatgggg caaacctatc aacccaatat
    19801 gtttgtcggc accagcaatc tagagtctgc tatggagaaa ctgcgttcaa cctttggcga
    19861 atatggcttg ggtactgcga caggaattga cctaccagat gaatctactg gatttgttcc
    19921 caaagagtat agctttgcta attacattac taatgccttt gggcagtttg ataactatac
    19981 gccgatgcag ttggctcagt atgtagcaac tattgcaaat aatggtgttc gtgtggctcc
    20041 tcgtattgtt gaaggcattt atggtaataa tgataaggga ggactgggtg acttgattca
    20101 gcaactgcaa ccgacagaga tgaataaggt caatatatcc gactccgata tgagcatctt
    20161 gcaccaaggt ttttatcagg ttgcccatgg tactagtgga ttgacaactg gacgtgcctt
    20221 ttcaaatggt gccttggtat ccattagcgg aaaaacaggt acagccgaaa gctatgtggc
    20281 agatggtcag caagcaacca ataccaatgc ggtggcctat gccccatctg ataatcccca
    20341 aatcgctgtc gcagtggtct ttcctcataa taccaatcta acaaatggtg taggaccttc
    20401 cattgcgcgt gacattatca atctgtatca aaaataccat ccaatgaact agaaaggaaa
    20461 ttatgcttta tccaacacct attgccaagt tgattgacag ttattctaag ttaccaggta
    20521 tcgggattaa gacggctacg cgtctggcct tttatacgat tgggatgtct gctgatgatg
    20581 tcaatgaatt tgcaaaaaat ctcctttctg ctaagagaga attgacatat tgttctattt
    20641 gtggacgttt gacagacgac gatccttgtt ctatctgtac tgatccgact cgtgaccaga
    20701 caacaatttt agttcttgag gatagtagag atgtggcagc catggaaaat atccaagaat
    20761 accatggact ctatcatgtc cttcatggcc tcatttctcc tatgaatggt atcagtccgg
    20821 acgatatcaa tctcaagagc cttatgactc gtcttatgga tagtgaggtt tcagaagtga
    20881 ttgtggcgac taatgctaca gcggatggtg aagcgacttc catgtatctt tcacgtttgc
    20941 tcaagccggc tggtatcaag gttacgcgtc tagcacgagg tctcgctgtg ggagcggaca
    21001 ttgagtatgc ggacgaagtg acactcttac gagcgattga aaatcggaca gagttgtaag
    21061 tgtaggcaaa tttacgaact cccttcattt ataaaaaatc aaagaggctg aaaatcgttc
    21121 ctatcggcct cttttcgtat agtgtgatga gtaggatcag gttcaagttt taaaaaacca
    21181 agcaaatatg atatactaaa gagcgagtat tctagtagaa ttaggacaaa taatatgaaa
    21241 caaacgatta ttcttttata tggtggacgg agtgcggaac gcgaagtctc tgtcctttca
    21301 gctgagagtg tcatgcgtgc ggtcaattac gaccgtttca cagtcaagac tttctttatc
    21361 agtcagtcag gtgactttat caaaacgcag gaatttagtc atgctccggg gcaagaagac
    21421 cgtctcatga ccaatgaaac cattgattgg gataagaaag ttgcaccaag tgctatctac
    21481 gaagaaggtg cagtggtctt tccagtcctt cacgggccaa tgggagaaga tggctctgtt
    21541 caaggattct tggaagtttt gaaaatgcct tacgttggtt gcaacatttt gtcatcaagt
    21601 cttgccatgg ataaaatcac gactaagcgt gttctggaat ctgctggtat tgcccaagtt
    21661 ccttatgtgg ctatcgttga aggcgatgat gtgactgcta aaatcgctga agtggaagaa
    21721 aaattggctt atccagtctt cactaagccg tcaaacatgg ggtctagtgt cggtatttct
    21781 aggtctgaaa accaagaaga actccgtcaa gccttaaaac ttgccttccg atatgacagc
    21841 cgtgtcttgg ttgagcaagg agtgaatgcc cgtgaaattg aggttggcct cttgggtaac
    21901 tacgatgtca agagcacgct acctggagaa gttgtcaagg acgttgcctt ttatgactac
    21961 gatgccaagt atattgataa caaggttact atggatattc ctgccaaaat cagtgatgat
    22021 gtggtggctg tcatgcgtca aaatgcagaa acagccttcc gtgccattgg tggccttggt
    22081 ctatctcgtt gcgatttctt ctatacagat aagggagaga tttttctcaa cgagctcaat
    22141 accatgccag gttttaccca gtggtctatg tacccactac tttgggacaa tatggggatc
    22201 agctacccag aactaatcga gcgtttggtt gaccttgcca aggaaagttt tgacaagcgc
    22261 gaagcgcatt tgatataaaa tgaaagagag ggtagaagcc agaaccatca ctgcacggtg
    22321 actagagttc tcggacttca gcccttttta aaggagtaga aatgaaatta acaatccatg
    22381 aaattgccca agttgttgga gccaaaaatg atatcagtat ctttgaggac acccagttag
    22441 aaaaagctga gtttgatagt cgtttgattg gaactggaga tttatttgtg ccacttaaag
    22501 gtgcgcgtga tggccatgac tttattgaaa cagcctttga aaatggtgca gcagtaacct
    22561 tgtctgagaa agaggtctca aatcatcctt acattctagt agatgatgtt ttgacagcct
    22621 ttcaatccct agcatcctac tatcttgaaa aaacgactgt tgatgtcttt gctgttacag
    22681 gttcaaatgg caagacaacg actaaggata tgttggcgca tttactgtca acgacctaca
    22741 agacctacaa aacacaaggc aactacaata acgagattgg ccttccctac acagttctac
    22801 acatgcctga aggaacagaa aagttggttt tggagatggg gcaggaccac ttgggcgata
    22861 ttcatctctt gtctgaattg gctcgtccaa aaacagccat cgtgaccttg gttggagaag
    22921 cccatttggc ctttttcaaa gaccgttcag agattgctaa gggaaaaatg caaattgcag
    22981 acggaatggc ttcaggttcc ttgcttttag tgccggctga ccctatcgta gaggactatt
    23041 tgccaactga taaaaaggtg gtccgttttg ggcaaggggc agagttggaa atcacagact
    23101 tggttgagcg taaggacagt ctgaccttta aggctaattt cttggaacaa gcccttgatt
    23161 tgccagtgac tggtaagtac aatgctacca atgctatgat tgcatcctat gttgccctac
    23221 aagaaggagt ttcagaggag caaattcatc aggccttcca aggtcttgaa ttgacgcgta
    23281 atcgtactga gtggaagaaa gcagccaatg gagcagatat cctgtcagac gtatataatg
    23341 ccaatccaac tgctatgaag ctgattttag agactttctc tgccattcca gccaatgaag
    23401 gtggcaagaa aattgcagtg ttggcggata tgaaggagct tggtgaccag tctattcaac
    23461 tccataacca gatgattttg agcctttctc cagatgtgct tgataccgtt attttctatg
    23521 gagaagacat tgctgaatta gcccaattgg ccagtcaaat gttcccaatt ggccacgttt
    23581 actacttcaa gaaaacagaa gaccaagacc aatttgaaga cctagtcaag caggtcaagg
    23641 aaagcctcag tgccaatgat caaatcttgc tcaagggctc taactctatg aacctagcca
    23701 tgttggtaga aagtttagaa aatgaaacca agtgattttg ttaagtatct gcaaagaatg
    23761 attgccctta cagatactgg cttaaccttt acaaaggatc cttttgaccg tgagcgctac
    23821 gaggacttgc gaagtctgtt atctgaaatg ttgaatcagg gatcagacct ggatgcagaa
    23881 gaagtagcag aagtcttgaa accaacttca gcttatgcga ctcccttaat ggacgtccgt
    23941 gcttggattg ttgaggatga gaagatttgt ctggttaggg gacaaggaga ggatagttgg
    24001 gctttgccag gtggctttgg tgaagtcggc tattctccaa ctgaaaatat tctcaaggaa
    24061 attgaagaag aaaccggttt taaagccaaa gttgaaagac tgctagctgt ttttgatacc
    24121 aatcgtttcc aactacagag caaacaatat gcaaagtttg tttttgaatg taagcttctc
    24181 gatggacaat tccaagaaaa tcaagaaatc gctgaccttc aattttttgc aattgaccaa
    24241 ctgccgaatt tatctgaaaa acgcattacc aaggagcaaa tcgagattct ttggcaggtt
    24301 tatcaaggtc agatggagca atatcttgac taagaagatg attatcgtat ttctaaattc
    24361 atttttctta agtagcatgg tataataaaa tgcaggaaaa ttttgaatta tgaggaagac
    24421 tagatgaatt tatgggatat tttctttacg actcaggcaa ccgagccgcc caaatttgac
    24481 cttttttggt atgttagcct atttacgctc ttagccttaa ccatttatac agcccatcgc
    24541 tatcgtgaaa agaaggttta ccaacgattt ttccaaatct tgcagactgt tcagttaatc
    24601 cttctttatg gttggtactg ggtcaatcat atgccactgt cagaaagcct acccttttac
    24661 cattgccgta tggctatgtt tgtggtactc ttgcttcctg gtcagtccaa atataaacaa
    24721 tactttgcat tattgggaat atttgggaca ttagcagcct ttgtttatcc agtgccagat
    24781 gcttaccctt ttccacatat caccatttta tcctttatct ttggtcattt agcactcttg
    24841 gggaactctc tagtttatct attgagacag tataatgcgc gattgctgga tgtgaaggga
    24901 atttttctca tgacctttgc tctaaatgcc ttgatttttg tggtcaattt ggtgacaggc
    24961 ggcgattacg gatttttgac aaaaccgcca ttggttgggg atcacggtct agtagctaat
    25021 tatttacttg tttcaattgt gctggtagct actatcagtt tgactaagaa aatcttagaa
    25081 ttctttttag ctcaagaagc agaaaaaatg attgcaaagg aagcttaaca cagagctttc
    25141 ttttttgctc ttagagagtt tttacaagca gcttataaaa taagaatttc tgaatagaca
    25201 aactcaaaaa atggctggga aatttaggaa aaaaacaagc acgattaaat tttttgtgtt
    25261 ataatatttt gtgaatagct atgcctatgt ttagctatgg aataatacga agtgcgaaac
    25321 ttggaagata gagaggaagc gatgtaatgg ctagagaagg cttttttaca ggtctagata
    25381 ttggaacaag ctctgtcaag gtgcttgtgg ccgagcagag aactggtgaa ttaaatgtaa
    25441 ttggcgtgag taatgccaaa agtaaaggtg taaaggatgg aattattgtt gatattgatg
    25501 cagcagcaac tgctatcaag tcagccattt cccaagcgga agaaaaggca ggcatttcga
    25561 ttaaatcagt aaatgtcggc ttgcctggta atcttttgca ggtagaacca actcagggga
    25621 tgattccagt aacatctgat actaaggaaa ttacggatca agatgttgaa aatgttgtca
    25681 aatcagcttt gacaaagagt atgacacctg accgtgaagt cattaccttt attcctgaag
    25741 aatttattgt ggatggtttc caagggattc gtgacccacg tggcatgatg ggggttcgcc
    25801 ttgaaatgcg tggtttgctt tatacaggac ctcgtactat cttgcacaat ttgcgtaaga
    25861 cggttgagcg tgcaggtgtt caggttgaaa atgttatcat ttcaccacta gcaatggttc
    25921 agtctgtttt gaacgaaggg gaacgtgaat ttggtgctac agtgattgat atgggggcag
    25981 gtcaaacgac tgtcgctaca atccgtaatc aagaactcca gttcacacat attctccaag
    26041 aaggtggaga ttatgtaact aaagatatct ccaaggtttt gaaaacctct cgcaaattag
    26101 cggaaggctt gaaactgaat tacggggaag cctatccgcc tcttgcaagc aaagaaacct
    26161 tccaagtaga ggttattgga gaagtagaag cagtcgaagt gacggaagcc tacttgtcag
    26221 aaattatttc tgcacgaatc aagcacatcc ttgaacaaat caagcaagaa ttagatagaa
    26281 ggcgtctatt ggacctccct ggtggtattg tcttaatcgg tgggaatgcc attttaccag
    26341 gtatggttga gcttgctcag gaagtctttg gcgtccgtgt caagctttat gttccaaatc
    26401 aagttggtat ccgtaatcca gcctttgcgc atgtgattag tttatcagaa tttgcgggtc
    26461 aattaacaga agttaatctt ttggctcagg gagcgataaa aggtgagaat gacttaagtc
    26521 atcagccaat tagttttggt gggatgctgc aaaaaacagc tcagtttgta caatcaacgc
    26581 ctgttcaacc agctcctgct ccagaagtag agccggtggc gcctacagaa ccaatggcgg
    26641 atttccaaca agcttcacaa aataaaccga aattagcaga tcgtttccgt ggcttgatcg
    26701 gaagcatgtt tgacgaataa agaggaaaaa taaattatga cattttcatt tgatacagct
    26761 gctgctcaag gggcagtgat taaagtaatt ggtgtcggtg gaggtggtgg caatgccatc
    26821 aaccgtatgg tcgacgaagg tgttacaggc gtagaattta tcgcagcaaa cacagatgta
    26881 caagcattga gtagtacaaa agctgagact gttattcagt tgggacctaa attgactcgt
    26941 ggtttgggtg caggaggtca acctgaggtt ggtcgtaaag ccgctgaaga aagcgaagaa
    27001 acactgacgg aagctattag tggtgccgat atggtcttca tcactgctgg tatgggagga
    27061 ggctctggaa ctggagctgc tcctgttatt gctcgtatcg ccaaagattt aggtgcgctt
    27121 acagttggtg ttgtaacacg tccctttggt tttgaaggaa gtaagcgtgg acaatttgct
    27181 gtagaaggaa tcaatcaact tcgtgagcat gtagacactc tattgattat ctcaaacaac
    27241 aatttgcttg aaattgttga taagaaaaca ccgcttttgg aggctcttag cgaagcggat
    27301 aacgttcttc gtcaaggtgt tcaagggatt accgatttga ttaccaatcc aggattgatt
    27361 aaccttgact ttgccgatgt gaaaacggta atggcaaaca aagggaatgc tcttatgggt
    27421 attggtatcg gtagtggaga agaacgtgtg gtagaagcgg cacgtaaggc aatctattca
    27481 ccacttcttg aaacaactat tgacggtgct gaggatgtta tcgtcaacgt tactggtggt
    27541 cttgacttaa ccttgattga ggcagaagag gcttcacaaa ttgtgaacca ggcagcaggt
    27601 caaggagtga acatctggct cggtacttca attgatgaaa gtatgcgtga tgaaattcgt
    27661 gtaacagttg tcgcaacggg tgttcgtcaa gaccgcgtag aaaaggttgt ggctccacaa
    27721 gctagatctg ctactaacta ccgtgagaca gtgaaaccag ctcattcaca tggctttgat
    27781 cgtcattttg atatggcaga aacagctgaa ttgccaaaac aaaatccacg tcgtttggaa
    27841 ccaactcagg catctgcttt tggtgattgg gatcttcgcc gtgaatcgat tgttcgtaca
    27901 acagattcag tcgtttctcc agtcgagcgc tttgaagccc caatttcaca agatgaagat
    27961 gaattggata cacctccatt tttcaaaaat cgttaagtaa atgaatgtaa aagaaaatac
    28021 agaacttgtt tttcgagaag ttgcagaggc tagtctgagt gctaatcgag agagtggttc
    28081 ggtctctgtc attgcagtta ccaagtatgt agatgtaccg acagcggaag ccttgcttcc
    28141 gctaggtgtt catcatatcg gtgaaaatcg tgtagataag tttctggaaa aatatgaagc
    28201 tttaaaagat cgagatgtga cttggcattt gattggtacc ttgcaaagac gtaaggtgaa
    28261 agatgtcatt caatacgttg attatttcca tgcattggac tcagtaaagc tagcagggga
    28321 aattcaaaaa agaagtgacc gagtcatcaa gtgtttcctt caagtaaata tttctaaaga
    28381 agaaagcaaa cacggttttt cgagagagga actgatggaa atcttgccag agttagccag
    28441 actagataag attgaatatg ttggtttaat gacgatggca ccttttgagg ctagcagtga
    28501 gcagttgaaa gagattttca aggcgaccca agatttacaa agagaaattc aagagaaaca
    28561 aattccaaat atgcctatga ccgagttaag tatgggaatg agtcgtgatt ataaagaagc
    28621 gattcaattc ggttccactt ttgttcgtat aggtacatca ttttttaagt aggagagaac
    28681 catgtcttta aaagatagat tcgatagatt tatagattat tttacggaga atgaggattc
    28741 aagtctccct tatgaaaaaa gagatgagcc tgtgtttact ccagtaaatt cttcacagga
    28801 accggctctc ccaatgaatc aaccttcaca gtcggctggt acaaaagaga acaatatcac
    28861 cagacttcat gcaagacaac aggaattggc aaatcagagt cagcgtgcaa cggataaggt
    28921 cattatagat gttcgttatc ctagaaaata tgaggatgca acagaaattg ttgatttatt
    28981 ggcaggaaac gaaagtatct tgattgattt tcagtatatg acagaggtgc aggctcgtcg
    29041 ttgtttggac tatttggatg gagcttgtca tgttttagct ggaaatttga aaaaggtagc
    29101 ttctaccatg tatttgttga caccagtgaa tgttattgta aatgttgaag atatccgttt
    29161 accagatgaa gatcaacagg gtgagttcgg ttttgatatg aagcgaaata gagtacgata
    29221 atgatttttt taattcgtat gatttataat gcagtggata tttactccct gattttggta
    29281 gccttcgctg tcatgtcttg gtttccaggt gcctacgaat ccagtttagg tcgttggatt
    29341 gtagcgttgg tgaaaccagt gcttgctccc ttgcaacgcc tgcctttaca gatagcgggt
    29401 cttgatttat ctatttgggt cgcgattgtt ttggttcgat ttttaggaga aaacctagtg
    29461 cgttttctgg cgatgatagg atgaataaag ggatttatca gcatttctcc atagaagatc
    29521 gtccatttct tgacaaggga atggaatgga taaagaaggt agaagatagc tatgctcctt
    29581 ttttaactcc ttttatcaat cctcatcagg agaagctatt aaagattttg gccaaaacct
    29641 atggtcttgc ttgtagcagt agtggggaat tcgtctcgag tgagtatgtt cgagttttat
    29701 tatacccaga ttatttccaa ccagagtttt cagattttga aatatctctc caggaaattg
    29761 tgtattccaa taaatttgaa catttaacgc atgctaagat tttagggaca gtcatcaatc
    29821 aattagggat tgaacggaaa ctttttggag atatcctagt agatgaagaa cgggcgcaga
    29881 ttatgattaa tcagcagttt cttcttctct ttcaagatgg actaaagaaa attggtcgta
    29941 tacctgtttc gctggaggaa cgtcctttca ccgagaaaat agataagcta gaacagtatc
    30001 gagaactgga tttatctgtg tctagttttc gattagatgt tcttttatca aatgttttga
    30061 aactatctag gaatcaagca aaccagttga ttgaaaagaa acttgtccaa gtaaattatc
    30121 atgtggtaga caaatcagat tacactgttc aagttggaga cttgattagt gtgagaaaat
    30181 ttggtcgctt gagattactt caagataagg gacaaacgaa aaaagagaag aaaaaaataa
    30241 ccgtccagtt attattaagt aagtgaggaa tagaatgcca attacatcat tagaaataaa
    30301 ggacaagact tttggaactc gattcagagg ttttgatcca gaagaagtcg atgaattttt
    30361 agatattgtg gttcatgatt acgaagatct tgtgcgtgcg aatcatgata aaaatttgcg
    30421 tattaagagt ttagaagagc gtttgtctta ctttgatgaa ataaaagatt cattgagcca
    30481 gtctgtattg attgctcagg atacagctga gagagtgaaa caggcggcgc atgaacgttc
    30541 aaacaatatc attcatcaag cagagcaaga tgcgcaacgc ttgttggaag aagctaaata
    30601 taaggcaaac gagattcttc gtcaagcaac tgataatgct aagaaagtcg ctgttgaaac
    30661 agaagaattg aagaacaaga gccgtgtctt ccaccaacgt ctcaaatcta caattgagag
    30721 tcagttggct attgttgaat cttcagattg ggaagatctt ctccgtccaa cagctactta
    30781 tcttcaaacc agtgatgaag cctttaaaga agtggttagc aaagtacttg gagaaccgat
    30841 tccagctcca attgaagaag aaccaattga tatgacacgt cagttctctc aagcagaaat
    30901 ggcagagtta caagctcgta ttgaggtagc cgataaagaa ttggctgaat ttgaagctca
    30961 gattaaacag gaagtggaag ctccaacttg tagtgagtcc tcaggttgaa gaagagcctc
    31021 tgctcatcca gttggcccaa tgtatgaaga accagaagta gctccagtgc atccgacagg
    31081 tccaacacca gctacagaaa ctgttgattc aataccggga tttgaagcac cgcaagaatc
    31141 tgttacaatt ttataagaaa tattctgaga acaatatctt atccttatat ttccagcgag
    31201 caggaaatgg tgtgagtcct gcattcccta tcgataagat tatcctctca aactatcaag
    31261 tctgaatcta gtaagatttg acgttcccca cgttacggga taagagagag aaagactaaa
    31321 tctttttccg aataaaggtg gtaccacgat tttcgtcctt tttggaagtc gtggttttta
    31381 atttgttatt atttataaag gagataccat gaaactcaaa gacaccctta atcttgggaa
    31441 aactgaattc ccaatgcgtg caggccttcc taccaaagag ccagtttggc aaaaggaatg
    31501 ggaagatgca aaactttatc aacgtcgtca agaattgaac caaggaaaac ctcatttcac
    31561 cttgcatgat ggccctccat acgctaacgg aaatatccac gttggacatg ctatgaacaa
    31621 gatttcaaaa gatatcattg ttcgttctaa gtctatgtca ggattttacg cgccatttat
    31681 tcctggttgg gatactcatg gtctgccaat cgagcaagtc ttgtcaaaac aaggtgtcaa
    31741 acgtaaagaa atggacttgg ttgagtactt gaaactttgc cgtgagtacg ctctttctca
    31801 agtagataaa caacgtgaag attttaaacg tttgggtgtt tctggtgact gggaaaatcc
    31861 atatgtgacc ttgactcctg actatgaagc agctcaaatt cgtgtatttg gtgagatggc
    31921 taataagggt tatatctacc gtggtgccaa gccagtttac tggtcatggt catctgagtc
    31981 agcccttgct gaagcagaga ttgaatacca tgacttggtt tcaacttccc tttactatgc
    32041 caacaaggta aaagatggca aaggagttct agatacagat acttatatcg ttgtctggac
    32101 aacgactcca tttaccatca cagcttctcg tggtttgacg gttggtgcag atattgatta
    32161 cgttttggtt caacctgctg gtgaagctcg taagtttgtc gttgctgctg aattattgac
    32221 tagcttgtct gagaaatttg gctgggctga tgttcaagtt ttggaaactt accgtggcca
    32281 agaacttaac cacatcgtaa cagaacaccc atgggataca gctgtagaag agttggtaat
    32341 tcttggtgac cacgttacga ctgactctgg tacaggtatt gtccatacag cccctggttt
    32401 tggtgaggac gactacaatg ttggtattgc taataatctt gaagtcgcag tgactgttga
    32461 tgaacgtggt atcatgatga agaatgctgg tcctgagttt gaaggtcaat tctatgaaaa
    32521 ggtagttcca actgttattg aaaaacttgg taacctcctt cttgcccaag aagaaatctc
    32581 tcactcatat ccatttgact ggcgtactaa gaaaccaatc atctggcgtg cagttccaca
    32641 atggtttgcc tcagtttcta aattccgtca agaaatcttg gacgaaattg aaaaagtgaa
    32701 attccactca gaatggggta aagtccgtct ttacaatatg atccgtgacc gtggtgactg
    32761 ggttatctct cgtcaacgtg cttggggtgt tccacttcca atcttctatg cagaagacgg
    32821 tacagctatc atggtagctg aaacgattga acacgtagct caactttttg aagaacatgg
    32881 ttcaagcatt tggtgggaac gtgatgccaa agatctcttg ccagaaggat ttactcatcc
    32941 aggttcacca aacggcgagt tcaaaaaaga aactgatatc atggacgttt ggtttgactc
    33001 aggttcatca tggaatggag tggtggtaaa ccgtcctgaa ttgacttacc cagccgacct
    33061 ttacctagaa ggttctgacc aataccgtgg ttggtttaac tcatcactta tcacatctgt
    33121 tgccaaccat ggcgtagcac cttacaaaca aatcttgtca caaggttttg cccttgatgg
    33181 taaaggtgag aagatgtcta aatctcttgg aaataccatt gctccaagcg atgttgaaaa
    33241 acaattcggt gctgaaatct tgcgtctctg ggtaacaagt gttgactcaa gcaatgacgt
    33301 gcgtatctct atggatattt tgagccaagt ttctgaaact taccgtaaga ttcgtaacac
    33361 tcttcgtttc ttgattgcca atacatctga ctttaaccca gctcaagata cagtcgctta
    33421 cgatgagctt cgttcagttg ataagtacat gacgattcgc tttaaccagc ttgtcaagac
    33481 cattcgtgat gcctatgcag actttgaatt cttgacgatc tacaaggcct tggtgaactt
    33541 tatcaacgtt gacttgtcag ccttctacct tgattttgcc aaagatgttg tttacattga
    33601 aggtgccaaa tcactggaac gccgtcaaat gcagactgtc ttctatgaca ttcttgtcaa
    33661 aatcaccaaa ctcttgacac caatccttcc tcacactgcg gaagaaattt ggtcatatct
    33721 tgagtttgaa acagaagact tcgtccaatt gtcagaatta ccagaggctc aaacttttgc
    33781 taatcaagaa gaaatcttgg atacatgggc agccttcatg gacttccgtg gacaagctca
    33841 aaaagccttg gaagaagctc gtaatgcaaa agtaatcggt aaatcacttg aagcacactt
    33901 gacagtttat ccaaacgaag ttgtgaaaac tctactcgaa gcagtaaaca gcaatgtggc
    33961 tcaacttttg atcgtgtcag acttgaccat cgcagaagga ccagctccag aagctgccct
    34021 tagcttcgaa gatgtagcct tcacagttga acgcgctgca ggtgaagtat gtgaccgttg
    34081 ccgtcgtatt gacccaacaa cagcagaacg tagctaccag gcagttatct gtgaccactg
    34141 tgcaagcatc gtagaagaaa actttgcgga agcagtcgca gaaggatttg aagagaaata
    34201 agattgaaaa gtctaggcaa aattcaattt gagaagaaaa gacaactaat tttatagtct
    34261 attaaacgca ttgtatcacg tttttgaaca cctgatatga tgcgtttttt atttatttta
    34321 aaaatttgcg aggtatgact ttttatactc aacaagaatc aaagagaaac ttagcaagct
    34381 aacagtagta agataaaata gga
//
LOCUS       DAVKAU010000016        33044 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVKAU010000016 DAVKAU010000000
VERSION     DAVKAU010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.016"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..647
                     /locus_tag="VWX48_000947"
                     /pseudo
     CDS             1..647
                     /locus_tag="VWX48_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
     gene            complement(1287..1445)
                     /locus_tag="VWX48_000948"
     CDS             complement(1287..1445)
                     /locus_tag="VWX48_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU9171596.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEEILVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(1516..1962)
                     /locus_tag="VWX48_000949"
                     /pseudo
     CDS             complement(1516..1962)
                     /locus_tag="VWX48_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2038..2250)
                     /locus_tag="VWX48_000950"
     CDS             complement(2038..2250)
                     /locus_tag="VWX48_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9171597.1"
                     /translation="MTQLLLHADETSYRVLESDSQLTYYWTFLSGKAENQAITLYHHD
                     QRRSGLVVQEFLGDYSGYVHCNMLRQ"
     gene            complement(2259..2564)
                     /locus_tag="VWX48_000951"
     CDS             complement(2259..2564)
                     /locus_tag="VWX48_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEU9171598.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(2551..2745)
                     /locus_tag="VWX48_000952"
     CDS             complement(2551..2745)
                     /locus_tag="VWX48_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9171599.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(2942..3265)
                     /gene="tnpB"
                     /locus_tag="VWX48_000953"
     CDS             complement(2942..3265)
                     /gene="tnpB"
                     /locus_tag="VWX48_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9171600.1"
                     /translation="MTIHLSILGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWLSTEKDIKALTSEQVDWLMKGFS
                     ITPKI"
     gene            complement(3249..3431)
                     /locus_tag="VWX48_000954"
                     /pseudo
     CDS             complement(3249..3431)
                     /locus_tag="VWX48_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3735..5297)
                     /gene="guaA"
                     /locus_tag="VWX48_000955"
     CDS             complement(3735..5297)
                     /gene="guaA"
                     /locus_tag="VWX48_000955"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU9171601.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            5439..6137
                     /locus_tag="VWX48_000956"
     CDS             5439..6137
                     /locus_tag="VWX48_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9171602.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(6180..7078)
                     /locus_tag="VWX48_000957"
                     /pseudo
     CDS             complement(6180..7078)
                     /locus_tag="VWX48_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
     gene            complement(7087..8022)
                     /locus_tag="VWX48_000958"
     CDS             complement(7087..8022)
                     /locus_tag="VWX48_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU9171603.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(8019..8744)
                     /locus_tag="VWX48_000959"
     CDS             complement(8019..8744)
                     /locus_tag="VWX48_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU9171604.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESIEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(8828..9463)
                     /locus_tag="VWX48_000960"
     CDS             complement(8828..9463)
                     /locus_tag="VWX48_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU9171605.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(9465..10292)
                     /locus_tag="VWX48_000961"
     CDS             complement(9465..10292)
                     /locus_tag="VWX48_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9171606.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINTLFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(10314..11379)
                     /locus_tag="VWX48_000962"
                     /pseudo
     CDS             complement(10314..11379)
                     /locus_tag="VWX48_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813133.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            11892..12503
                     /locus_tag="VWX48_000963"
     CDS             11892..12503
                     /locus_tag="VWX48_000963"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9171607.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            12548..13276
                     /gene="rlmB"
                     /locus_tag="VWX48_000964"
     CDS             12548..13276
                     /gene="rlmB"
                     /locus_tag="VWX48_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU9171608.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(13314..14225)
                     /gene="trxB"
                     /locus_tag="VWX48_000965"
     CDS             complement(13314..14225)
                     /gene="trxB"
                     /locus_tag="VWX48_000965"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU9171609.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(14291..14515)
                     /locus_tag="VWX48_000966"
     CDS             complement(14291..14515)
                     /locus_tag="VWX48_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU9171610.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(14593..15336)
                     /locus_tag="VWX48_000967"
     CDS             complement(14593..15336)
                     /locus_tag="VWX48_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9171611.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMPFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFTSYKRTYI"
     gene            complement(15336..16136)
                     /locus_tag="VWX48_000968"
     CDS             complement(15336..16136)
                     /locus_tag="VWX48_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9171612.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(16294..16650)
                     /locus_tag="VWX48_000969"
     CDS             complement(16294..16650)
                     /locus_tag="VWX48_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU9171613.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(16644..17174)
                     /locus_tag="VWX48_000970"
     CDS             complement(16644..17174)
                     /locus_tag="VWX48_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU9171614.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGESQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(17174..17668)
                     /locus_tag="VWX48_000971"
     CDS             complement(17174..17668)
                     /locus_tag="VWX48_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171615.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            17803..18249
                     /locus_tag="VWX48_000972"
     CDS             17803..18249
                     /locus_tag="VWX48_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU9171616.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            18246..18893
                     /locus_tag="VWX48_000973"
     CDS             18246..18893
                     /locus_tag="VWX48_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU9171617.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWILMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(18914..19495)
                     /gene="pdxT"
                     /locus_tag="VWX48_000974"
     CDS             complement(18914..19495)
                     /gene="pdxT"
                     /locus_tag="VWX48_000974"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU9171618.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESYLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(19496..20371)
                     /gene="pdxS"
                     /locus_tag="VWX48_000975"
     CDS             complement(19496..20371)
                     /gene="pdxS"
                     /locus_tag="VWX48_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU9171619.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(20523..21902)
                     /locus_tag="VWX48_000976"
     CDS             complement(20523..21902)
                     /locus_tag="VWX48_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU9171620.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            22196..23119
                     /locus_tag="VWX48_000977"
     CDS             22196..23119
                     /locus_tag="VWX48_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU9171621.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVNGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            23179..23784
                     /locus_tag="VWX48_000978"
     CDS             23179..23784
                     /locus_tag="VWX48_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9171622.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            23803..25047
                     /locus_tag="VWX48_000979"
     CDS             23803..25047
                     /locus_tag="VWX48_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9171623.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGINAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(25270..25527)
                     /locus_tag="VWX48_000980"
     CDS             complement(25270..25527)
                     /locus_tag="VWX48_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU9171624.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(25569..27605)
                     /locus_tag="VWX48_000981"
     CDS             complement(25569..27605)
                     /locus_tag="VWX48_000981"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU9171625.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(27865..28782)
                     /gene="glyQ"
                     /locus_tag="VWX48_000982"
     CDS             complement(27865..28782)
                     /gene="glyQ"
                     /locus_tag="VWX48_000982"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU9171626.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISNQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(28977..29738)
                     /locus_tag="VWX48_000983"
     CDS             complement(28977..29738)
                     /locus_tag="VWX48_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9171627.1"
                     /translation="MENLYLVKDDSQLAAFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSNFNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICTQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWLSFLIVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(30011..30853)
                     /locus_tag="VWX48_000984"
     CDS             complement(30011..30853)
                     /locus_tag="VWX48_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU9171628.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(30967..32358)
                     /locus_tag="VWX48_000985"
     CDS             complement(30967..32358)
                     /locus_tag="VWX48_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU9171629.1"
                     /translation="MDKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKKHFRKGQAEVIAYYPIQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(32593..32973)
                     /locus_tag="VWX48_000986"
     CDS             complement(32593..32973)
                     /locus_tag="VWX48_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9171630.1"
                     /translation="MTCQFIRDMLDLPAKNVTILEGSDIHVLPSMPYSAQDFYTSIDD
                     VLAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKHIAP
                     VYAIAIVDSNYFSDDLAFHSFIVK"
BASE COUNT         9871 a         7278 c         5908 g         9987 t
ORIGIN      
        1 gagaaaaatg gagttcccct ttcagatgtt tggaatatac catttcttaa tccaaaagct
       61 aaagaaagag taggttatcc tacacaaaaa cctattctgt tattagaaca aattataaag
      121 attgctactg ataaaaatga tatagtttta gacccgttct gtggaagtgg aactacttta
      181 gtagcctcca agattttgaa tagaaattat atggggattg atttatctga ggaagctatc
      241 aatataactc agcaacgtct ggaaaatgtt ataaaaacaa gttcaaattt attgaataaa
      301 ggaatcgaag catatagaac caaaactgag gaagaggaaa acattcttaa attattacag
      361 gcaaaaattg ttcaaagaaa taaaggaatt gatggttttt tacctaaaca ttttcaaaaa
      421 aaccgatacc tataaaaatt caaaaaaata atgaatgtct gaatgagagt atctctttat
      481 tacagaatgc tataaactcc aaaaaacttg attttggagt agttataaaa actcattcag
      541 ataatttatt atttgatttt gatacgattc ctgaaaatat aatagtagtt gaccattttg
      601 aacttacaat cgaaaaatgg ttaagtaaaa gtcaacagtt actatagttt gcaaattatt
      661 tacagaaaga acaaaaaatg ctctgaaaca ctgatttcaa agcatttttt gttagtttaa
      721 aattactccc attcttcttt tccaaacgta caatatatcc aaaaccattc aaaatactag
      781 attctatttt ttataatatc actaaatcca cctaattata ggacgttttc agatttttag
      841 tcccgtccca gtcccagtac cggagaaata ttgttttaat ataatatctc tttttgtctt
      901 ctaagctctt aaaagcaaaa gaacaagtaa agagtcaaga caaggataaa aagtccatat
      961 tagggcaaat aaaaagcttt aagacagatg acaaatctaa gtcaaataag aaagaccata
     1021 gcaaaggtgc agagagataa atattggcgg tcttcggact gcctttattt ttttacttaa
     1081 tttaatgcag taaatcatac gattgaaagg aatctgcgtt atatgctata attaggtagt
     1141 taatctatac atttagaaag gtaaaatata gaattggaga atgatatggg attttcatat
     1201 aataaattgt aaccgcccaa taacgaagta tattgaaaaa tctccagact agagaactca
     1261 cggatagttc ctaatctgga gatttcttat ttgcactttt cttgtacaac tttagtccat
     1321 ggtaaatagg cctctaaaac ctctttgttt acgagaattt cctcgtttgg aagacattct
     1381 agaagatagg atagatattt ctcactattt agttgatgac gtttagctgt ttccaataag
     1441 ctcataataa tagctcttgc tttagctcct tcaaaacttt gagaaaataa ccaccctcgc
     1501 ttttttaaac tgagctcagg ctaaaagagt ccactggact cttttattcc gtcccataac
     1561 caatgactta atggcgcgtt cagctagatt attggaaagg accagatgtc cgtctttcaa
     1621 aatagtctta aaggtttctt catacttgag gctgtattca attgcccttc ctagttttga
     1681 acccgataaa actgactgac gccggcacca agcaaagaaa tcttccatta ggggttggag
     1741 ctcttcttga cgtttctgta gtcgttcatc agctgacaat gtctcccagt ctctttccaa
     1801 ggcaaataac tgatcacaat aggctaatcc tttagctcct aaggatgatt tatccgcttg
     1861 cttgggggtc gcttcaaaaa acttccttct cacatgtacc caacatccaa caagttcagc
     1921 ttcttccagt tgacgataag cttctagcgg ttcgcagttt accaagctta gcgtcgcctt
     1981 gctcctaagc cttggactgc tatcgcatag gcagaactag aggactaaag ttctaagtta
     2041 ctgccgcaac atattacaat gcacatagcc agaataatct cctaggaatt cttgtactac
     2101 taaaccactc cgacgctgat catggtggta cagcgtgatt gcttgattct cagctttccc
     2161 agacaaaaaa gtccaatagt aagtcaactg actatcactc tctagaaccc tataagaagt
     2221 ttcatccgca tgaagtaaga gctgagtcaa tagtctcgtt ataaaggggc tttaggaata
     2281 ggagctttca cgattttatc actcggattt ttatcactgc atgcttggca tttgtaagcg
     2341 tgttggatat gatctatgcg ttttaattgc gcaggaataa agactaattc ttgtcgttga
     2401 agggttgctc caatctcttt tagatctccc tgacaatcag agcaaatgct ctcttctact
     2461 tgatgatgaa cttcttctga atcaaattgg gcaagaagag cttggcgttt ccctttagat
     2521 ttcttacgtt tgtaggtaat ttcctctgtt tcaactggga acatctccat cttcctcaga
     2581 tggagactct tcctcaaaaa ggttgagttg tccagagggg caaacacttt tctcagagga
     2641 ttttccatag agcttttgag tcagataagc cacttgttca cgcagaaggg caagttcatt
     2701 ggtgagacta tcaattgtag cactctgttg ttgaatgatt ttcaatcttc ttccatgagc
     2761 ttccctctct gttttctaac tttattatac taaaaagaaa gtcctcattt caatagaaat
     2821 cacgactttc tgatggattt atagtaaaat gaaataagaa caggacaaat cgatcaggac
     2881 agtaaaatcg atttctaaca atgttttaga agcagaggtg tactattcta gtttcaatct
     2941 actatatttt tggagtgata gaaaagccct tcataagcca gtctacttgt tcagatgtga
     3001 gagctttgat atccttttct gtacttagcc aagtcagtct gccgttctca aagcgtttat
     3061 atagtagcca aaatccttga ccatcccagt aaaggacttt aaagcggtct ttacgtccac
     3121 cacaaaagag aaagacttga ccggagaaag gatccaattc aaagtgggtt ttaaccagat
     3181 aagccagtga atcgattcct tgtctcatat ccgttttccc acacacgaga tagacctgcc
     3241 ctaggataga tagatgaatt gtcatagagc aacaccttat ccaaaagctg ttctaccatt
     3301 tcgagattga gagattgaaa aaaacttact tcaagcttgc caatacgaat tttaagcaga
     3361 atatcatttc tctttttaga atcaaaacga cgagattgtg gaatctctac aggaacaata
     3421 ggttgtggca ttaaaatatc ctccaatagt tttactttac taatagtata caggaggagc
     3481 tccatgaatg atagatacct tgttatgacg cgcttactat attagaaagt tggctctcta
     3541 attaaattaa ttctcattat atatatcaaa agaccgcagc ttgaaaacta cggtctaatt
     3601 ttttgtccaa atgtaaacca cttggaacta ttattcaatt tattcttttt agtaaatgtt
     3661 cccgttttaa tcccagttac agtttttaat cctctgtaac cgttgatttt acaaagcttt
     3721 taattttttt gcgattattc ccactcaact gttgcaggtg gtttacttgt aatatcgtag
     3781 acgatacggt taacatgatc cacttcattt acgatacgta ctgagatttt ttgaagtact
     3841 tcccatggaa ttttggcaaa atcagcagtc ataccatcga tagaagtgat agcacggatt
     3901 gcaatcgtgt agtcatacgt acgaccgtca cccataacgc cgactgaacg aacgcctgtg
     3961 ttaacagtga agtattgcca aatatcgcgg tcaagtccag ctttagcgat ttcttcacga
     4021 agaatagcgt ctgattcacg aacggtttca agtttctctt cagtgatttc acccatgaca
     4081 cggatagcaa gtcctggtcc tgggaatggt tggcgccata cgatatggtc tggcatacca
     4141 agctctgtac caagagcacg aacttcatcc ttgtaaagag tattgagtgg ttcaatcaat
     4201 tcaaactgca tatcttctgg aagaccaccc acgttgtggt gtgacttgat agtttgagct
     4261 gtatccgtac cagactcgat aacatctgta tataaagtac cttgagcaag gaatttcaca
     4321 tctttgagct tgcttgcttc gtcatcgaat acatagacaa actcgttacc gatgatttta
     4381 cgtttttgtt cagggtcaga aacgccagca agtttgtcaa ggaaacgttt agcagcgtct
     4441 gctttgacga tattcaaacc aaacttacca ccgagcatgt ccataacttg atcagcttcg
     4501 cctttacgaa gaagaccgtg gtctacgaag atacagatca attgatcgcc aatcgctttt
     4561 tggagaagaa ccccaacgac agatgagtca acaccacctg atagaccaag aaggacacgt
     4621 ttatcaccga cggtttcacg aatttttttg atctgcatgt caatgaaatt atccattgac
     4681 cagtcacctt tagccttaca aatgttaagg gcaaagttac gaaggatatc atttccgtat
     4741 acagaatgac gaacttctgg gtggaattgg ataccgtaaa tgtgtttatc tgggttttcg
     4801 atggctgcgt atgggcagtc agctgatgta cctgtacgaa caaagtcagc aggaatctca
     4861 gtaaccgcat caccatggct catcaaaaca gtctgttcat caggtgttga ttcaaaaagc
     4921 gctgatggtg tgtgagttag ggttgattga ccgtattcac gatttccagc atcacctgca
     4981 ggaacaactt ttcctccaag tttatgggtc aataactgca taccataaca gattcccaaa
     5041 attggaattc ctagttcgaa gatttctggg tcaatgtcaa atgaaccatc ttcatataca
     5101 gaatttggac cacctgatag aataattcct acaggattga cttcacgaac ttcagcagct
     5161 gaaattttat ggctttttag ttctgaaaaa acaccaatct cacggatacg gcgtgaaatc
     5221 agctggttgt actggctacc atagtccaat acgatgattt tttctacatc ttgcaaatca
     5281 gttgaaatgt tgctcatctt tttcctttct caaaagaaat atcttttctc aatattctat
     5341 cacaaataag ggcgaattac caactaaaca aggcgaagtt tgactttttc tagtttattg
     5401 gggtacaata gagaaaagat agaaatgaag tgaaaaatat gctacctgct tatatgaaaa
     5461 tccatgatca gataaaaaag gatattgacg agcaccgttg ggctattggt gagaggcttc
     5521 ccagtgaaag agatttagct gagcagtttg cggtcagtcg catgaccctc cgccaagccg
     5581 tatctctatt agtcgaagaa ggcgtcttag agcgccgtgt aggaagcggc acctttgttt
     5641 ccagtactcg agtacaagaa aagatgcgag ggacaaccag ttttactgaa attgtcaaat
     5701 cccaaggtaa agttccctct agccagctca tttcctacaa aaaaaccatt cccaatgagc
     5761 aagaagttgc caagctagga atttttccaa cggacaatat tatccgaatg gagcgggtcc
     5821 gctatgccga ccaagttccc ctagtttatg aagttgcttc tattcctgaa aaattcatta
     5881 aggactttaa aaaagaagaa atcaccagtc atttcttcca aaccttgcaa aaatatggct
     5941 atcgtatcgg caaatctcaa cagaccatct atgctcgcct tgctaaagaa aagattgccc
     6001 actatttgga agttgaaaaa ggacatgcta ttcttggatt gacccaggtt tcctacctag
     6061 aagatggtac tgcttttgaa tacgtaaaaa gtcaatatgt aggcgaacgc tttgaatttt
     6121 atcttgaaaa taattagatt accacgcaaa aactctctgt cacagacaaa gagtcttttt
     6181 tatttttcta agaataaatc tttcaaagaa atcaaagtta cagcaaacaa tatcattgcc
     6241 ataccaataa aatcaatggg ataaaattgt tcattcatta ttaagaaggc aaagaaaacc
     6301 gccgatattg gctcaattga agccaacaag cttgacttga ccggtcctat cagactggct
     6361 cctttaagga aagctgtata ggcaaagaca gtcccgataa ggataatgcc tgcaaacgca
     6421 aggagaaaat caagactagt cgggatatcg gcctgtagaa tccctgtaaa aggaagggcg
     6481 accaaacctg ctatgaccat tcccacacca atgaccaagc tgctccccca ctttttaatc
     6541 aaggctatgg gtaaaatgat atacaaagca taagtcaagg cagaaaagag accccagaac
     6601 agaccagcag gtgtcatgga taactggtcc aactgcccat gtgttgcgat caggaaggtt
     6661 cctccgatgg cgaatatgat ggaaactatc tctcccagtg tcggtgccac cctatccttg
     6721 atacagcgct ataaattaaa attccgacag gacaaacata ctgaagcacc gtcgctgttc
     6781 ccgcattggt ctcctgaata gcagacagat aggcgaattg gttgagaaaa agaccaatca
     6841 gagcaaaaat aagaagagac agcaaactct ttctatcctt taaaaagacc agtattttat
     6901 cctttgcagt agcataagcc aagagcatga gaattccacc agcgattaaa agacgcaagt
     6961 tggtcaagac cagagccgaa attccgtgtg ccattaggta ttggccactc gttcctgaca
     7021 acccccaagc aataccagcc acaactgtta gtaaagtccc ttttaaacta tttgacatgt
     7081 ctctccttac tcttctttgc gaatcaagtt catcacttga ttgcggtcta atatccattg
     7141 agctctctcg tccttttcat aggtacgatt cgataggaaa atagtggctt cttgcttctg
     7201 acgattccac atgataaagg tacctgtata gcccgtatgg tctagccaat ctccttccaa
     7261 attccatgct aaagaacgtt ccttgtcatc caaaggagaa aaattttgat ttaagtctct
     7321 tgcaaaatca tctgctaaat agtgttctaa aaagatttgt aaatccttta tagtcgaaaa
     7381 taaaccagca ctcccagcat gtctacccag gagacgagcc ttgggatcat gcactatgcc
     7441 tgcctctaca cctctaactg ttggaacagc aagctcaact ggcccaaact tggtttccgt
     7501 cattccccaa ggtttccaga cttgatcctt taaaatcaca tccaaatctt gattaaaaat
     7561 tctttccaaa ataaagccca acagcaaaaa atggacatcc gaataaagaa aggctggctg
     7621 acttcgtctg ttgagatgaa acatcgcttc ctttaattca ggggctgtta aaagatcacg
     7681 attaggaata aaaggatcaa ggtctgttgc atgagtcaag agctggcgaa tagtgatgtc
     7741 tggataatca ctctcaggta aaaaatctat taccagtcta tcaatatcta attgacctat
     7801 ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc ttgctgacac tagctaggtc
     7861 ataaactagt cctgcctcag tctgcaagcc atgctctggg tcactctggc ctaaatagaa
     7921 ctctgtccat tgattgtcct taaaatacgc aaaagaggct ccgggataaa tccctgcctc
     7981 gatttgttct tctatttttt taataatctt ggtccacttc atacttcttc aaaccacaat
     8041 tcaacattat ttctatcttt accaaggaag aatttttcag acttaggaat aaaatattca
     8101 atagactcaa acttctggcg aagacttgct atgtctaatt cattgaccaa gaacttgagc
     8161 atagataagt cccaggtaac cgtattgtcc acagtcaaat cctgcccctg agctggaata
     8221 aaatcaaggg atgccccaat ttcagatgat tccaagaaac tttcgatatc agttgggaga
     8281 tgtaattcca tagaaatctc aaatttactt aaagaaattg atgccaaatc tgtttgaaat
     8341 tcaggctttt ctcctacttc tactagactt gctctgtcat cttccgcatg aatcaaaatc
     8401 aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat tttgaccttt atataatcga
     8461 tgaatcgaat ctgttttaga taagattcct tcaatttcta agggattttc caccttgaca
     8521 atcaatctag ctagtttttt tcttccctct accttacgag tacgcatact gggagcttct
     8581 tctaaaacca gcttttcaag acccgtttgg tcacctagtg acagaaaggc cgattcttct
     8641 aacaaggcct tcattccaag ggtttcaata taaaatgttt catttaattt tctattatta
     8701 gcttttaaag taggaataat ccgtacaatc tgatttacat tcataaattc ctccgtcact
     8761 ttttatttta aaggatttta gaatttttta caagatatta tgctcaaatt taacattatt
     8821 tagctattta gtaaagatag tctttcaagg cttttgacaa agcctgataa ccagcaatac
     8881 tgaggtgcag tccatcagtt gtatattctt ttttgagttg gcctgcttgg tctgtcaaac
     8941 aatcaaatac tggcacaaat tccacctgca tataggcaga tgcaagctct tgataggctt
     9001 gattccagtt ctgaattttt tcattcgagc ggatatagac tgcctgctgg tactcctctc
     9061 cctcattgac aggcaaaatg gaaagcaatt taatctctgt caatggataa tcgcgagcaa
     9121 cggattgaat gatagcttcg agattattga gagcctcatt cacaggaaca tcctttccga
     9181 tatcatttgt cccaatcaga agaaaaattt tatctactgc tccaccatat agatgagcat
     9241 caaggttctc tagtaacagt cctgtctgat agccacgaat tcctcgattg acaatcgtct
     9301 ttgaagtccc aaatagctcc tgtagaggat aatactcgac aatggaatcc ccaataaaaa
     9361 gaatgtttgg ttctacaaca gaaatgtgat ttaggtgacg atacttggtt tgaatttttt
     9421 cttgttcctt taggagccaa ttttctaata actgtactgc cacttcattc tcctttttct
     9481 aaccagtttt ccaagacttg ataaactcct ccttggctgt tggctggtgc tagagcagtc
     9541 gccacagctt tggctttctc atcagcattt tccatcgcat aggcaattcc agccatttca
     9601 agcatttcaa catcattttc actatcacca aaagccatga tttcttggga tttcaagtcc
     9661 cagcgcttga gtaattcctc caagccccat gctttatgaa tcccagcttg gaggatatca
     9721 atgcaaccat agccactgga tacagctcgg acacggccat caaagagagt attgatttct
     9781 tccaaaaccg aactcaaacg ttcctcacca acaaccatgc tcatcttgag cacaccacca
     9841 aagaggtcag atgttaattc atccacaaat tgcatccgtt ggtagaattt ttcaatcatt
     9901 tctggagtca taaaactttc aagatctgta aaaatcgtac cttccttgac aaaatcaccc
     9961 ttcatccccg ttacaacaaa ctggtcctga cacgctcgac ccttgaaatg agccaaagcc
    10021 ttgttgacaa tggcgtcatc ccatgtctga gcctgaatca attcattgtt ttcaaaaata
    10081 cgagcgccat tagcaacaac cagaaccact cgatccacca agggactcag tagttgtctc
    10141 atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa tgcccctttg atccaactga
    10201 tctaaaatct tttccaatcg tgggagatca agctgacctc tagcatccag caaggtccca
    10261 tccatatctg tcgcaattac cttaatcatc atttactttc ctctggattc aaactaatac
    10321 cacttcaatc ccacatgttc attcatttct ttataggctg tatcaattcg ttccttagtc
    10381 gcttcatcta actggtcacg atgactgcca tcctctataa aatcttccaa aatataagtt
    10441 tggtaatgat acaagggata tccttctggt gaaaaggttc cctttggtgt tcgattgacc
    10501 caagtaggat gatctttagc tgttccgata gttgtttttc catcattctt cttgatggtg
    10561 acatccatga gaacaccacg ttcagtccac ttagcattct cttcatctcc catagattca
    10621 attcgttgat tggaaatgaa gttccccatt gaatagataa tgagtttctt atctccatct
    10681 ttttcaaccg tttcagatgg ctcaacaacg tgaggatgcc ctccaaagat aatatccgct
    10741 ccccaatcga tcatcttgtg ataaagagct ttttgttctt cagttggttc caatcgatac
    10801 tcaacaccca tctgaggcat gataatggtg atatctgctt ccttctctgc ccgttcaact
    10861 tcagccttca tcttatcttc gtttaaatct aaaagataac gattatagtc ttcctgagaa
    10921 atatactgct caattccatt gaaaccatag gaataggctg acaatgcaac cttgatacca
    10981 ttcacttcct taatgaccag cggaacctga tcacgtggtt cgtgcgtata aactccgatt
    11041 ggagtgattc cagctttctc aataatatcg gccgttgaaa taactccctc aatttgcgaa
    11101 tccaaaatat gattatgagc taaatccagc acatgataac ctgcctcctt aatagcatcc
    11161 ataacttcag caggagcatt aaagagagga taacccgcta aataatgatc cttattaatg
    11221 gtttcttcaa aatcaccaat agctaaatct gcttgcttag tccacttgct tgagccaagg
    11281 agtcacatac tcaaaatttt catgaaagtc ataggtaccg tcttcttttt tagctgaaaa
    11341 gaaaagtcca tcgtggtaga gcaaatcccc gtgggccata attctggcag ttttttcctc
    11401 ttcctactcc tgagactttt gcttagtccc ctcttgagaa atagtatctc gtttttgact
    11461 agtcaaggga ttccttggaa gctttcaaac aacaagacca agcccattga taaaccaact
    11521 gctagcaaga gtatcgccac aaatccctta ttgctccact tgcgataact cctaaaaagt
    11581 ttaccaagcc cttcataaaa cgaaaagcta aaccaccctg atttcgattt tgtcttcttt
    11641 gtatcttcgt tctccctact ttcttatgca agccttttct ttttattata tcacagataa
    11701 gtatttcttt cacaattgaa ttgaacttcc catctatttt ctataaatcc taaatgccat
    11761 aatgctttca attcttgtca ttttgtgata tcatgtagag gaaatgaact aatccacagt
    11821 ggcttattcc aagtatacca cttgggcttt ggcagtagct aactgcacta aacataatat
    11881 aaggagagaa aatgtctgca atagaacgta ttacaaaagc tgctcactta attgatatga
    11941 acgatattat ccgtgaaggg aatcctactc tacgcacggt tgctgaggaa gtcactttcc
    12001 ccctatctga ccaggaaatc atcctaggcg aaaagatgat gcaattcctt aaacattccc
    12061 aagatcctgt catggctgaa aaaatgggac tccgcggtgg tgttggactg gctgctcccc
    12121 agttagatat ctcaaaacgc attatcgctg ttttggtacc taatattgtt gaagaaggcg
    12181 aaactccaca ggaagcctac gatttggaag ccattatgta caatccaaaa atcgtctctc
    12241 actctgttca agatgctgct cttggcgaag gagaaggttg cctgtctgtt gaccgtaacg
    12301 tgcctggcta tgttgttcgc catgcccgcg ttactgttga ctactttgac aaagatggag
    12361 aaaaacaccg tatcaaactc aaaggctaca actccattgt tgttcagcat gaaattgacc
    12421 acattaacgg tatcatgttt tacgatcgca tcaatgaaaa agacccattt gcagttaaag
    12481 atggtttact gattcttgaa taaagaaaat cccgttgcaa gacggggttt tgtgttataa
    12541 tagaggcatg aaaacaaatg atattgtcta tggtgtccac gccgttaccg aagccctcct
    12601 tgcaaataca ggaaacaaac tctacctcca agaagatctc cgaggtaaga atgttgagaa
    12661 agtcaaggaa ctagctacag aaaagaaggt gtccatttct tggacatcaa aaaaatctct
    12721 ctctgagatt actgaaggtg ctgttcatca aggttttgtt ctacgagtgt ctgaatttgc
    12781 ctatagcgag ctagattaca tccttgcaaa aacacgccaa gaagaaaatc cacttctatt
    12841 gattctagat ggtctaaccg atccccataa tctgggttct atcttgcgaa cagccgatgc
    12901 gaccaatgtt tcaggtgtca tcattcccaa gcaccgtgct gtcggagtaa ctcctgtcgt
    12961 tgccaaaaca gccacaggtg ctattgaaca cgttccaatt gcccgagtga ccaacctcag
    13021 tcaaacctta gataaactca aggatgaagg tttctggacc tttggaacgg atatgaacgg
    13081 tactccttgc cacaagtgga atacaaaagg gaaaatcgcc ctcatcattg gaaatgaagg
    13141 aaaaggtatc tctagcaaca tcaaaaaaca agtcgatgag atgattacca ttccgatgaa
    13201 tggacatgtt caaagcctta atgccagtgt tgctgcggcc attctcatgt acgaagtttt
    13261 ccgaaataga ctataaaaag tttccagtca tctgattgga aactttttta taattaacta
    13321 tgttctgtaa tgaatttata ggcttcttga ccagcgatag ctccatctcc aaccgctgtt
    13381 gttacttggc gaaggtcttt caagcgaaca tctccaactg caaagatacc gtcgactgca
    13441 gttttcatgt ggttatctgt cacaatccat cctgcctgat cttggatatt caattcttta
    13501 acaaaatcgc taagagggtc caatccaaca tagataaaga caccaccgaa gacttgttct
    13561 gtcacttgac ctgttttcac attttcaaat acgactgatt ctactcggtt ttcacccttg
    13621 atttccctta ctacagaatc ccagataaag ctgatttttt cattcgcaaa ggcgcgatct
    13681 tgtaaaacct tttgggcacg aagttggtca cgacggtgaa caatggtaac agtcttagca
    13741 aaacgagtca agaagagggc ttcttcaaca gctgaatctc caccaccaac taccaataaa
    13801 tcttggtcac ggaagaaagc accatcacac acagcacagt aagaaacacc acgactgttc
    13861 agttcttctt ctccaggtac tcccaaagga cggtgtttag aaccagttgc tacgataact
    13921 gtacgtgttt catatgtttg gtcatcagtc atcactttct taaaatcacc atggtcttcg
    13981 acattttcaa cataaccata aatgtgctca acaccaagat tttcaagtgg ttcaaacatc
    14041 ttttcagcca attcaggtcc actaatatta gcgtatcctg ggtaattttc gatatcagat
    14101 gtattattca tctgaccacc tggcagacca ccttcaatca aagctacttt tagattgctt
    14161 cgagcagcat acaaggccgc agtcatccct gcaggtccag caccgataat aatagtatcg
    14221 tacatataga ttccttcttt cttgttgtaa ctatctttat tctaactctt tcttgtcaat
    14281 cacgcaagga ttatgccttg aaaacaagaa ttaaactcat aaccgcaaag gataatactg
    14341 ggacaaccaa gactccaatc ataatcatat catagagatg ggcttggcga gccttggctg
    14401 tcttatcaac tcccgacatg gctctcagac caatccaaat ccctaaaaaa atcagaacaa
    14461 ggatggtggt caagatcaaa ctctcgaaat ataaagaaaa tagttgcagt agcatgattt
    14521 ctctcatttc tatctttttt aaagagtaaa ctcagctagt ccaactaact gagttttcct
    14581 ttatctatta tatcaaatat aagtccgttt gtaactagtg aagaattctt ttgtccgctc
    14641 ttctttaggg gtgtggataa tctcatccgg agttccagac tcgatgattt tccccttatc
    14701 taagaagaga attttatccg caacttgggc tacaaagggc atgtcatgac tgaccaaaat
    14761 catggtctga cctgacttag cagcatctgc aatagacttt tctacttcac cgaccaattc
    14821 tgggtcaagg gctgaagttg gttcgtctaa gagcaaaaca tctggtttca tagcaagcgc
    14881 acgcgctagg gcaacccgtt gcttctgtcc acctgataaa tggcgaggat aatggttttc
    14941 acggtccgaa agcccaacct tagccaactc ttccttggca atcttagtcg cttcttggtc
    15001 agataatttc ttgacaacaa ccaagccttc tttcacatta tcaagtgctg ttcggcgttc
    15061 aaataaatta aactgttgga aaaccataga caacttacgg cgtagggcaa ggatttcttc
    15121 ttgagtgatt ttagaaaaat caactgaaaa accatcaatc tgaatagagc cactgtcagg
    15181 tgtttcaaga taattgagac tgcgaagaaa ggttgatttt ccagctcctg aagaaccaat
    15241 caaggctaca acttcccctt tttgaatatc caagttcaga tgatccaaga cagtctgtcc
    15301 tgaaaaggat ttgcttaaat tcgaaatctt aatcattaac gaaggtctcc tttcacatct
    15361 gtttgcactg tatcaggtgc agaaatagcc atttttctct cgatgaaacg accgaggctt
    15421 tcaattccga tattgactac ccaataaaca agggcaacag agatgaagcg ttcaaaatag
    15481 cgataatcag ctccacctag aatctgagct tgggcaaaga cttccacaac acccgcacta
    15541 aaagctagag atgttccctt ggtcaaaccg atgagggaat taatcaaggt tggagtagct
    15601 accaccgctg cattaggaat aatcactcgt cgataaactt gcgctcgggt catacccaga
    15661 ctgcgcgccg cctcaatctc accaggatta actgagagaa tggctgcacg aatggtttca
    15721 ctagcataag ctgcctcatt aaaggcaaaa gcgacaatcg caaaagctgc agctggaatc
    15781 gcattgatat tgagaccagt tccccattgc tgattgaggg ctttcaaagc caaagggatt
    15841 ccgtagtagg tcaacatgag ttgcaccaaa atcggtgtcc cttttaagaa actaacaaag
    15901 aaggcctgca agggatataa aatcttgaca cgattgatct tcacaatggc aaaaagaagc
    15961 gccaaaacca agccaaaaag ggcaccgcca attgtcaaca taattgttgt tggaagttgt
    16021 tggacaattc tagggattcc atcaaagacc gaacgtaggc taaacagctt gccatccgga
    16081 atcaattgca tcaagttttg gtaccaatct gatgctaaaa tcgttgtaac attcataaaa
    16141 acatcctctt ctgataatga ttcattctac catgcttctg ccgtcaatga aattatttgc
    16201 tacggtcaga tacagacttt gtctacctac tagtttatca tactttgaaa cagggaagtt
    16261 atatatttta tctatcaaag agatagataa aaactatttc agtcccagtt cttcataaga
    16321 ttttcgataa ccgatttgct taacagttcc attttctact aaaatgggcc gttttaacaa
    16381 cataccgtca cttgctagca actcagccgc ttcttggttt gacaaacttc ctaccttatc
    16441 ttttagccct aattcacggt atttgatacc actggtgttg aaaaattgct tcaattcaaa
    16501 tcctgaggtt tctagccaat tcaaaatgac ttcttggcta ggtgtttctt ccacgatatg
    16561 gacggcttta tagtccacac ctaattgatt taattcttgt tttgcttttt tacaagttga
    16621 acatttgggg tattcgataa attctaacat gtgcttctcc ttctattgtt tctatcttta
    16681 aaatctactc cttcatgctc caagagccaa gctttctttt ccactcctgc agcataacct
    16741 gtcagacgct tgcctgctcc caacacacga tgacaaggta ctaggataga ccaaggattg
    16801 cgtcccactg ctccaccaat tgcttgagca gaagccactt gcaggtcttg agcaatttgt
    16861 ccataggtca ctgtctgacc ataaggaatt ccctgtaaat aggaccaaac tctcttttca
    16921 aaattcgttc caattggcgc caagagcaag ttggataaat cctgagactc gcctttaaag
    16981 taatcatcta agcaagcaat aactgggtct aaaataggat gactaacaac ttcttctatc
    17041 gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct gaacccaaat tccatacaaa
    17101 taatggtcat cagctacaag tgatagaata ccaattggtg aggagtagag tatttttaca
    17161 tacttctttt gcattatttc tttaattttt gataggccaa gcgttcgcca tctactggca
    17221 ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg ttgcataacc ttgttttcag
    17281 catgcgtatc tgagcgaaaa tcaagataat caaaaccttc aatcaagccc tctaagaagg
    17341 tttgagcaac tccttttccc tgcacatctg ctgccacagc aatacggtga aagactagat
    17401 actctgactc tccagcttgc cagtttccct cataaatagc ttcataggcc tcctctggac
    17461 tcttggtcac agcagcatag gctagcagtt ctccctcttc caaggctacg taggcttgcc
    17521 ctgagatgat atcatcgata ataacatctg catttggata gccattttgc cactggtcac
    17581 taccagcatc tgctaaacat tttttggcat cctccatcac ctgcatgatg gcatctactt
    17641 catttggaaa agctaaacga atttccatct tttttcctca tttctgacta gtttctccca
    17701 tcatagcata atttaagtat ttctacaagc agttaaaact tgactttgtg tttttgttat
    17761 tttataatct agttatcaaa actatataaa aaggagttga aaatgaaaac taccttttcc
    17821 tacccaaaat gggcagaaat tccaaacatt gacctctatc tggaccaggt tttgctctat
    17881 gtcaatcagg tctgcgcccc tatctctcct aataaagaca agggcctaac agcatctatg
    17941 gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg acaaaaaaaa ataccaacgc
    18001 caacagattg cccgtttgat tgctatcaca accctcaagt ctgtattttc tattcaagaa
    18061 atagcccaga cacttaatac tctacaaact caagcaagtt cagaccaact ctacgatgct
    18121 tttgtggact atatgaacca aggaattgac ccagctaacc ctattatcca aaccagctgc
    18181 caaaccgtta aactctatca tcaaactcta gacttaatcg atcatactca agaggaggta
    18241 atccaatgaa cactagtctt aaactcagca aacaactcag ttttggagag gagattgcta
    18301 atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat cttgctgcct atttcatcca
    18361 tctatagtta tgaagcacac ggatttttat cctctatcgg cgtttccatt ttcgtcatca
    18421 gtctctttct catgttccta tcatccacca tttatcactc tatggcctat ggttcgaccc
    18481 acaaatatgt tttgcgaatc attgaccatt ctatgattta cgttgccatt gccggctcat
    18541 acacgcccgt tgtcttgacc ttgatgaata actggtttgg ctatctgatt attgtcatcc
    18601 aatggggaac gaccatcttt ggtattctct ataaaatctt tgctaaaaag gtcaatgaga
    18661 aatttagcct tgctctttac ctgattatgg gctggttggt tctggctatc attcctgcca
    18721 ttatcagtca aacgacaccc gttttctgga ttctcatggt aactggcgga ctctgttata
    18781 cagttggagc tggattttat gccaagaaaa aaccttattt ccacatgatt tggcatctct
    18841 ttatcctagc tgcgtccgta ctccaataca tcgctattgt ttattacatg taaaaaagtt
    18901 gagaaattca atctcaactt ttttctttac acatattgat aaagtactgg tgcaagcgca
    18961 catcatcagt caattctgga tgaaaagaac ttaccaacat atttttttct tgggctgcaa
    19021 caatttgatt gttcactgtt gctagaattt ctacaccctc accaacacta ctgataatcg
    19081 gaccacggat aaaggtcatt ggaatcttgc caactccctt acattctgct tccgtgtaga
    19141 aacttcctaa ttggcgccca taagcattac gctcgaccac catatccata gttcctagat
    19201 aactctcttt ctgagaagtg atttccttag ccagcaaaat taagcccgca caggtcccaa
    19261 acactggtaa gccagataga atggcttctc ggatgggaag tagcatgttc tggtcacgta
    19321 agagcttgcc catggttgta gactcaccac caggcaaaat caaacccgac aagtcactct
    19381 gatcttgctg aaaatcatct agatttctga gttctacact ctcgacacct aattgatcta
    19441 gcacttttgc atgttctgca aaggcccctt gcaaggccaa tattccgatt ttcatctatt
    19501 ttcctcgttc agccatgaga atttggattt cattttcatt aataccaacc atggcttctc
    19561 ctaaatcttc agagatttga gctaggattt gaggattacg gaagttagtc acagccttaa
    19621 caatggcact cgctcgttta acaggatctc ctgacttgaa aatacctgaa ccgacaaaga
    19681 ccccctctgc ccctaattgc atcattaacg cagcatctgc tggcgttgca acacctccag
    19741 cagcgaaatt tacaactggc aattttccat gttcatgaac atattggacc aattctacag
    19801 ggacttgcaa atccttggca gcaacataaa gctcgtcctc acgtaagttt tgaatgcggc
    19861 gaatttcctg attcatcata cgcatatgac gaacagcttg gacgatatcc cctgtccctg
    19921 gttctccttt ggtacgaatc atggaagcac cttcagcgat acgacgcaag gcttcaccca
    19981 aatccttagc accacagaca aaaggaactt ggaattcttt cttgtccaca tggaaacggt
    20041 catcagctgg agatagaact tcactctcgt cgatataatc aatttcaata gcctctaaaa
    20101 tctgagcttc aacaaaatgc ccgattctga ccttagccat tactggaata ctaaccgctt
    20161 cttggatttc cttaatcatc tttgggtcgc tcatgcggga aactcctcca gctgcacgaa
    20221 tatcagccgg aattcgttcc aaggccatca cagctgccgc accagcagct tctgcgatac
    20281 gagcctgttc aggattctgc acatccataa taacaccacc cttgagcatc tgtgccaagt
    20341 ttttatttag ttcataacga ttttcagtca tttgttttat cctcatcatt tgtattggta
    20401 gctacctttt cattttaagt cagaacagaa tgaagcacaa gataaaaaaa ctataattgt
    20461 atggggacag attggctaaa aactatctga ccttaactta aggccagata gctcattcat
    20521 ttttattttt cagccgtaag ggcagccatt gtgatgtagt tgtatggttt attgaagtgt
    20581 ggcaagaaga agaggtctgt caatgccaat ttatcaattg tcacatgctc ttggatagca
    20641 agtgagaaca tgtggattcc catgctaatt gcaatatcat gtgaaaccat ttgggcacca
    20701 agaatttcac ggctatcttt gtcaaagaca atcttaattg ctacttcatg gttgtcatgt
    20761 ttcatgaatt ctggtttttg aagatcgtta aagcctgttt cagttgcgtt gtaaccagca
    20821 gctttcgctt tttcaagagt caaaccagtt gaaaccatgt gaagaccgta gattgagata
    20881 ccatttgaac cttgaacacc gattccttcc aattcatgtc cacaagcgtt gtaggcacca
    20941 acgataccag tgcgaacagc atttgaagca agagcgatat agcttgtatc tttacgagca
    21001 ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc ctgggataga tgtttcttgt
    21061 ttcttgtcta caaggaaggc accgttgcgg aagagttcga tcttaccatc agcaagggct
    21121 gtgtttggac ggaaaccaac tgcaaggata accatatcca cgtcaaagct ttctttgtca
    21181 gtaatcaagc gttcaacttt accatcacct tcgattgctt taacagtttg acctagagcc
    21241 aagcggatgt tgtgatcttc caagttcttc gccatcattt gtgtgaagtc tttgtcatag
    21301 taaccgttca agacagtatc aacgatatca acaaggacaa cttcttttcc aagacgttca
    21361 aaggcttcag caagttcaac accgatgtaa ccaccaccaa caacggcgat acggtcgagg
    21421 tgttggctct tgtcagaaag tttattgata acttcttcag cattttggta caatttcacg
    21481 aattgtacgt tttcaagagt tgctttaaat tcgcggtttc ctttaacaat ttcaacacct
    21541 tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa tcaatttttc gtatgattct
    21601 ttgtgctctt ttccttcaac ttccgctgta actactttgt tatcatagtc gattgaaaga
    21661 acaggtgagt tcatgtaaac tttagcacct ttagcttcca atttttcttt atcagaatag
    21721 aacaagcctt cagcaccgtc aatttgttca ccaatccaaa gagccattcc acatcctagg
    21781 aaagagatgt tagagttttg gtcaaataca acaatttcgt tctcatttcc aaaattatcc
    21841 aacatggtat tgatacatgc tgtaccagcg tggttagcac cgactacaac gattttactc
    21901 ataaaaattt cctgccttca ttctaaattt accttactag tataccattt accgttagcg
    21961 tttacaaggg gggtactatt atttcagcat tttttatcaa aaataattcc ccatttatcc
    22021 tgttttcaag cctcatgaat tttatgagca tatttcttga ctttttccaa attttgtttg
    22081 tgaaaattct aactttatgg tattctaata acatgaaaat aaaatgtaag ggcttcaatt
    22141 tagataatta ttttatatta caacttattt tctataagag aaaggagttg gtagcttgac
    22201 tcttcgttca cattctgaac ggctaatggg gactactatc actatttcat tagtggatga
    22261 gcaagccgat atctttctcc aaaaatcctt tgacttgctc aaagagcttg aataccgctt
    22321 caacgccaat agtcaagaat ctgagttgat ggaaatcaat tatcaagcag gaatatcccc
    22381 cgtcacggtt catccagacc tgtttgagct gatttcactt gggttagagc atagcctagc
    22441 gctctctagc cacctcaata tcagcattgg tcccttaatt caaacctggc gtatcggttt
    22501 ttcagatgcc aaggtcgccc agcctcaaga aattgaatcg gtgctgcctc taatcaatcc
    22561 tcatggtatc gagttagatt cttctacttc tactgtgttt ttaaaacaga aaggaatgaa
    22621 gatcgatcta ggttgtttag ccaaaggata cagtgcggat aaggttgccc aatttcttag
    22681 gaaagagggg gtgacttctg ccttgatcaa tctgggaggg aatatcctga ccattggaaa
    22741 aaatcaggca agaggggata acccatggca aatcgggatt caagacccag ccaatcctag
    22801 gggaaatcat ttaatgacca tccctgttgt caataaatct gtcgtgactt caggcattta
    22861 tgaacgtcac ctgaccgtca atggacaaga ttaccatcac atttttgaca gtcaaacagg
    22921 atatcctgtt gaaacggaac tagcgagtct aacaatcatc tctgataaat cagtcgatgg
    22981 cgaaatctgg acgactcgac tctttggaga aagacctgct tctatcctct ggcaagtcga
    23041 aagtttggag ggcatcgaag tcatcctcat cgataaagaa ggccacctaa gctgttcttc
    23101 aggaattcct actctataga gacaactgtt tcaatggaat tttaaaattg tattatgtaa
    23161 aaagagaaag gaaatctcat gttaaaactt attgctattg ttggaacaaa ttcaaaacgt
    23221 tctacaaacc gtcaattgct tcaatacatg caaaaacact ttgctgacaa agctgaaatt
    23281 gaacttgttg aaatcaaggc cattcctgtc ttcaacaaac cagctgacaa gcaagtacct
    23341 gctgaaatat tggaaattgc tgctaaaatc gaagaggcag atggcgttat tatcggtact
    23401 cctgagtatg atcactctat tccagctgtt ttgatgagcg ctcttgcttg gttgtcttat
    23461 ggtatttacc cacttttgaa caaaccaatc atgattacag gtgcttctta cggtacgctt
    23521 ggttcatctc gtgcccaatt gcaacttcgt caaatcttga atgctcctga aatcaaggca
    23581 aatgttcttc cagatgaatt cttgctctca cactctcttc aagcatttaa cccaagtggc
    23641 gacttggttg accttgatgt tatcaagaaa ttggatgcca tctttgatga cttccgtatc
    23701 tttgtaaaaa tcacagaaaa attacgtaat gcacaagaat tacttcgcaa agatgctgaa
    23761 gactttgact gggaaaattt gtaagatagg agaccaaaaa gaatgaaatt tgttggactt
    23821 gttggatcaa actacgatca atcatataac cgtaagctct tggaatttat ccgccgctac
    23881 ttcaaactca aatttgaatt agaagttctt gaaattgacg aagttccaat gtttaaccaa
    23941 gatgaaaaat gggatgaaag tttccaatta cgttatttat ataacaaaat tactcgtgca
    24001 gatggtgtta tcattgctac tcctgagcac aaccacacta tctcagcttc actcaaatct
    24061 gtacttgaat ggctttcata cgaagttcat ccatttgaaa acaagcctgt tatgattgtg
    24121 ggtgcatcat actatgacca aggaacatca cgtgctcaag ttcaccttcg taaaatcctt
    24181 gatgctccag gtattaatgc ctacacgctt ccaggtaacg aattccttct tggtaaagct
    24241 aaggaagctt ttgataacaa cggaaatatc accaacgaag gcactgttaa attccttgaa
    24301 acttgcttag ataactttgt taaatacgta ggagtcgttt cgaaattgaa aaaaccaaaa
    24361 ccaatcgaat cagaagactt ggattgtgga aaaccaatcg ctacaaccat cacagaagtt
    24421 gaccctgacg atccagaatg ggtagaaaaa gttgcagcaa tcactggtgc tgtttctggt
    24481 gatacctatg tcaaattgga ccacggtatc ctaacagtta accaaattga tatgttcttg
    24541 aaagctatgc catttgaatt gacatacgct gatgacaaca accaattcct ctactacaac
    24601 aacgctcacc aagatccaga cactatgttc gctaaacgtg taccacctca atcaggtagc
    24661 cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta tgaagaacgt agagtgggtt
    24721 atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta cgatcgttcc aggttctcct
    24781 gcaggtgtta tcaacactca caactaccaa gcaatgtact atcctgatgg atcatacgct
    24841 ggtatcaatg aaatcgtctt taacttccaa ccatggcttg actggtacct aaaagagact
    24901 ggtcaacgtt tggtgggtgg tagcggacca tttgctcctg ctgccggagg tcatggagac
    24961 gccgatgcta cttctggcgc ttctgattca ggggatgctg gaggccacgg tggtgacgca
    25021 gacgctacag ccggtgcaag ttactaatga tagtttttag gaaccattat ggttcctttt
    25081 ttagcgaaaa aagactagca aacacaaact gctagtctct ttgttatcgt ttcatctatc
    25141 cttgttaaaa gaaagaatac ttatactcaa tgaaaatcaa agagcaaact aggaagctag
    25201 ccgcaggctg tacttaagta cggcaaggtg aagctgacgt ggtttgaatt tgattttcga
    25261 agagtattat tatgaatttg ggtcatcaag actacggcca tgtaatcctt tttcacgttg
    25321 tacttggcgt agtttttctg gtgtaacatc gtttccttct tcgtccacaa ttttgattcc
    25381 ttcaatgtgg tgacgaacag cgcggcgata accttcgatg tactcctcac gtagtttggc
    25441 ttgttccact ttttcttctg gtgttaaacc ttctgttttt ttctttttag caagctcatt
    25501 gatacgagca atttttttcg gatccatttc ttctcctttg taataagata aagtccgttt
    25561 atcaaatttt atttagtgtt aatttggtta aaacaagcaa acttagctgc tttcttggtt
    25621 agttgtgaca agattgccaa acgattttga cggacagcct gatcttcagc cattaccata
    25681 gtattttcaa agaaagcatc aatgactggg ctaagcgcaa agagttgttt caattgctga
    25741 cttgcaggtc ctgataaaac gagtgtttct actgcttctg ccaaagcttt ttcttggtca
    25801 ttctcaaata gtgctgaatc aactgtagca accccttctg ccttctcagc caggttaaag
    25861 gcacgagaaa gtgattcaac agatggttta aaatcttctt ccttgcttac ttctacgaga
    25921 gcacttgctg cttccaacat atctgccaca acaaagtttg aacctgcaag aactgcttcc
    25981 ttgatatctt ttggagtaga gcccatcatc ttatcaacac gagccttgat aaagtccata
    26041 acctctgctt tattttcata agtcaaactg tcaaatttca atgcataaag gctatcaatc
    26101 agctcatcca tagcaatgtg ccaaccaaag gcatccaaga tacgaaccac accttgagtt
    26161 gcacgacgaa gggcataagg gtcattagaa cctgatggaa tcaatcctac tgagaagaaa
    26221 ctcaaaatcg tatccaattt gtctgcaatg gctagaactg caccgacctt gctctctgga
    26281 agttctcctt cagctgatgt aggcatgtag tgttcacgaa tagcagctgc caccgctgga
    26341 gtttcaccag caagaagggt gtatttttca cccataattc cttggagttc gtcaaattca
    26401 ccaaccatac ctgtcaacaa gtcaaacttg taaatggctg ctgcacgagc aaggtcaact
    26461 gtttcatcca ctgacaaacc agctttttct gccaaaagta cagtgatttg acccgtacga
    26521 atcatgtgtt cacgaaggga accaatcttc tcatggaagg tgacattgtt taatttttca
    26581 acaagatctg aaatcaccaa tttttggtct tcacgccaga agaattctcc gtcttccaag
    26641 cgggctacca agactttttc atttcctttg atgacatttt tcaaacgctc tgcgtttccg
    26701 ttacgaacag aaatgaagtt tggcaagagt tttccatctt gatcacgaac aacaaagtaa
    26761 cgctggtgtt ccttcataga agttaccaag acttcttctg gaacttcaag gtatttagca
    26821 tcaaaacttc ccatgaaggc agttgggtat tcaaccaaat tcaagacttc attcagcaaa
    26881 tccgcatcaa tttcgatacg tacaccatgt tttgcctcaa ttttcttgat ttggtcaaca
    26941 atcatttgct cacgttcaca tggatctgcg attacaaact gcttacgaag gtcttcttca
    27001 tagctcaatg ctgactgaat tttggtttct ttccccaaga aacgatggcc acggctcaca
    27061 cgacctccct tgatatcaag gaaatccaag tcaaactctt gctcatccaa gagaacagtt
    27121 aaagtgtgaa cagggcggat gtattcaaag ctgtttccag cccagtgcat gctgacaggg
    27181 aaagtcaatg acttcaagac atctacaaca ccaggaacaa tggcttcaac tgcttgacca
    27241 acttcttcct tagtgacata gacatattct tcacccttga tttcacggaa ttcgatatct
    27301 tcaacagtca agccttttcc acggacaaat ccttgagctg ctttggtgaa gtttccatca
    27361 ctatccaagg caattttctt tgctggtccc ttgaaatctt ctgtcaaatc agactgtttg
    27421 tctgataaac cagtcacacg aacagccaaa cgacgtggtg ttgagaaggt ttgaatggct
    27481 tcaaaagaca ggcggttttc cttgaggaag gctgccattt tttcgcctag ttgtttttca
    27541 cttggtgtga caacataggc tggtaattct tcaagaccga gttctactaa taagtttttt
    27601 gtcatgtttt ttcctttaca ttttcttcaa tcttttttga tatgcacctt aggtactggg
    27661 gacgtcgcta actaactctg tgagtctgta tggaaatcca atgctaaatt tatcaagatt
    27721 tccaacaatc tcatcaaagt ggatttagct gactgatttt tgaacctaag gtttcaaaaa
    27781 tccccacata acagtacggc ggtgcatatc cctctagcaa gtcttcgact tgcctctaac
    27841 gattttagag tacagtatta ctcactattc tgcgtcttct gctaaaagtt taactcgtgt
    27901 ttcttcatcc aaaagtgggt aacctaggcg tttgcgttct gcaacaaagg ttttggctac
    27961 aacacgggcc aagttacgga tacgagcgat atagcctgca cgctctgtta cagatacggc
    28021 accacgcgcg tcaagcagat taaaggtatg tgaacatttg agaacatagt cataggcagg
    28081 gtgtaccaag ccttcttcta atgcacgacc agcttctttt tcaaacttat caaagttttc
    28141 aagcaacatt tcttggttcg aaatttcaaa tgaatatttt gagtgctcat actcaggctg
    28201 gataaagatt tctccgtatt ttacaccatc agcccactcg atatcataga cagagtctac
    28261 ttcttgaatg taagaagcca agcgctccaa accataggta acttccgcag tcacagggcc
    28321 agttgccaat ccaccgactt gttggaaata agtgaactga gtgatttcca ttccgtcaag
    28381 ccaaacttcc caaccaagac cagctgaacc agttgatggg ttttcccagt tgtcctcaac
    28441 aaaacgaata tcgtgctcca aaggattgat tcccaatttt tccaaagact caaggtaaag
    28501 ttcttggata tttgatggag aaggcttcat gaccacctgg aattggtggt gttggtagag
    28561 acggttaggg ttttccccat aacgaccgtc agcaggacga cgtgatggct ctacataagc
    28621 tgcattccat ggctcaggtc cgatagcacg aaggaaagtg taaggactca ttgttcccgc
    28681 acctttttca ttatcataag cctgcataag catacaacct tggtcattcc aaaattgttg
    28741 caaagtcaaa ataatttctt gaaatgttaa tttcttagac attgaatact ccttaataaa
    28801 aaataatttc ttgcgacacg agtctgcctc gtcgattata cgaggcaaga cgagttagta
    28861 ctgcgtctag ctcaggcact ctagtgctga gcgtggagca gcccgactgt aaggaggtct
    28921 ctgccactga tgcagtgaaa tgttaatttc ttagacattg tttactcctt tagtttttat
    28981 atttcttttt caattaattt ctgctgaaca aaccaatcta acaagggaaa agttttttct
    29041 gtatttgccc atagatgata agaatcaaag accgcttgta cactacctaa attttctacc
    29101 aacttatcta ctatcaaaaa actgagccaa tattcataaa aaatacttgc atagttctta
    29161 tcataagtcg aagaaccaaa atcattcaat gaatgccaac catacttctt ctgaaaaagt
    29221 tctactagag attgagtaca aattttttcc gcttgaaatt cctcttctgt caagaaatac
    29281 ttgcgactaa tatattcaac catcccctct tcgaaccaga tataagagtc ataaccatca
    29341 aaatcatcta aaaaatgctc cgaccaatga gctaactcat gtcctacaat ctgtaagagg
    29401 aaattttcag ataaagaatg atagtgactt tctattgctt gagtttgctg agaacactcg
    29461 tagtccatca attgatacaa atacaactct ttccaaacag ctaaatcagg cgtcataacc
    29521 attcgtctat tatttgtata ggctggaaca gcgctttccc taataatctg tgtagcagca
    29581 ttaaaatttg accaaataac ggcttgcggt aaatcacaga ctgcaagttc attctttaaa
    29641 aaagattgat aatctttcaa cttttcagta tttcttacta caaaatcacg aaatgcagct
    29701 agttgactat cgtcttttac aagataaagg ttttccacgt ctctcctttc tttcacacaa
    29761 tagactgaat aagcaaaaga accacatctg acaatcctag gttgatttaa cctaggggcg
    29821 tcagaaacgc ggttccaccc taatttatta cttcattgtt tttgaaaata ctacagaaag
    29881 cgccagctca ttattttgcc ctacttggct cccactgtcc caagctcgct tgaagaacgc
    29941 cataagactc tctttcctgc tgactattat atcaaaaatt agaataatgt acaattcttt
    30001 ttatgatttt ctagaaatcc acatcatcaa ctcgtggagc acccgattga acagcaatcg
    30061 tttttaaggt ttctctctcc tcatgactca gttcaattcc aaaacaatca agattagctt
    30121 gaatacgaga ggttgtgaca gattttggaa gtggtaaaaa tccttctgcc aagctccagg
    30181 ccaaggctat ctgagcaacc gattttccgt gatttgctgc tatttcttgg acttgcttgc
    30241 tatcaaacag ttctccttgt ccaaaaggcc cccaagcttc caataaaatt cccttttcac
    30301 gacagtaagc tacgacttga tcttgataca cacctggcgc caagcgaact tgattgaccg
    30361 caggaacgat agttgcagtt tcaagcaagg catccaaatg atggggaaga aaattgctaa
    30421 cgccgatagc acggattttc ccttcttgat agaggtcttc catcgctctc caaacttccg
    30481 cattgcgagt tttccatgcg tcattttctc tgagcggttt tgggttcggc caatgaatca
    30541 aatacaaatc caaataatcc aagcccagtt tttctataga tttttccaaa gcttgacgag
    30601 tttgctcata ggtttgctga ctattccaaa gcttggtagt tacgaacatt tcttcacgtg
    30661 gaactccgct atctttgatt gcttgaccaa cactttcttc attctgataa atcgccgccg
    30721 tatcaatatg acgataacca gccttcaagg cttctaacac tgcacgatag gcttcttctc
    30781 catccttagc cttaaaagtt ccaaatccca atactggaat ttctactcca ttatttaatt
    30841 gataggtatt catatgcttc tccttctatt ttattcatca attatagcat aaaacatttt
    30901 ttaagtagta ctatcttctg taaaaaataa gtctgtcaaa tatctaacag acctattttt
    30961 tcttgcttat tcatcacgac tatagtacag ctcatgagct tttaggcgag tattgagcat
    31021 ctctggtatg gtcacaaagg tataaccttg atttttcaaa tactcaatga cccttggcaa
    31081 ggcattgact gtcggactgt gaatatcatg catcaaaacg atagagccgt tagctacttg
    31141 atgctgaatt tctgtcaaaa tagatgcttc atttttactc ttccagtcca gactatccac
    31201 atcccacatg ataaagctca aatccaagct attgcgaata tcatctgtaa tagcaccata
    31261 aggtggacgc atgagtttag aactagaacc cagcacttta gttagcacat cctcagtatc
    31321 agtaatctgc tttttagctt catcaagaga gagttgcgag agaatcggat ggctccaact
    31381 atggtttcca acaacatgac cttcagattt tatcctcttc accaagtcct cattcccaga
    31441 aacatttttc ccaagcacaa agaaagtcgc tttaatatca tatttagcta gggtctctaa
    31501 tacctgcggg gtcgttgctg gatttggacc atcatcaaag gttagagcga caactttttg
    31561 atgtttctta tcaaagtaag attggtacaa ggccgcatct ttttcgagta agtacgaaga
    31621 ttggataaca tcaaagaaag cagatactgg caaggctatc tcttctaaat tttcaaccac
    31681 aggacttgga taaaggataa tctgactatc cttgtaatca aaattccatg cagacaagtc
    31741 ttggtcagag aagtttttta caatctgctc actctggtct tgctctattt ttttatcctc
    31801 tatgaaggag gtcaactctt ttatcagctg ttccttagcc ttactagcat ctgaaaacag
    31861 ttggtcaagt gtaaaaggtt gcccatcttc tgttaagtga acctttccta gactggtctt
    31921 ttcagtctct tcaatcttaa aagcaactaa atcatagatt tgtttggtca cattacgatt
    31981 aacgactccc tttaaacctg actcttcttg ctctgtatag tagaaaacaa gattgtcctt
    32041 actttctagc ttgtccttaa catcttgatt tatcagctcc ctaacagagg aaatcacttt
    32101 ctccccttgg atagggtaat aggcaatcac ttcggcttgc cccttacgaa aatgcttctt
    32161 ctgatttccc tcactcaatt gatcatcttt ctcttttttg agcgattcaa tcttttgctc
    32221 aaaacttttt tgctggtaga tcttaaaagc aataaatccg cctaataggc aaatagaaat
    32281 tgctaaaata ccaatcaaag ccaataatac atgtctcgtt ttcccgtgtc tgccacgtcc
    32341 cagtctactt ttatccatat ttatatcata acaaatttga gaaataattt caatgataca
    32401 atttggcaat ccacaattcc tctagcaagc caaagcatct tacatcaact ccaacatccg
    32461 tatctgtaga gattatgtag ttttctatct atggaatttc tagtggattg aaactagaat
    32521 agtagaccta tacttctaaa acattgttag aaatcgattt gactgtcctg ttcgatttgt
    32581 cctgttttta tttcatttta ctataaaact atgaaaagct aggtcatctg agaagtaatt
    32641 actatcgaca attgcgatag cgtatactgg tgcgatgtgt ttgtagctct ggtgggtatc
    32701 accttcacgt tgacggattt tttcaaggtt ttgattaacc tgactgcaca gataagccca
    32761 taggcgattg atgaaaaaat tttgatgatg aacctgaatt tcgatgataa cttgggttcc
    32821 attatctaac tccgccaaga cgtcgtctat actagtatag aaatcctgcg ctgagtaggg
    32881 catggaaggc aagacatgaa tatcgcttcc ctccaaaatg gtcacatttt ttgctggcaa
    32941 gtccagcata tcgcgaataa attgacaagt cattggtcgg gctaatgccc ggatgtctta
    33001 gaatcatcct tttcctcctt ctatagtgaa ttgaaataag atgt
//
LOCUS       DAVKAU010000017        31973 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVKAU010000017 DAVKAU010000000
VERSION     DAVKAU010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.017"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            179..1660
                     /locus_tag="VWX48_000987"
     CDS             179..1660
                     /locus_tag="VWX48_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9171631.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2021..3022
                     /locus_tag="VWX48_000988"
     CDS             2021..3022
                     /locus_tag="VWX48_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9171632.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3172..4089
                     /locus_tag="VWX48_000989"
     CDS             3172..4089
                     /locus_tag="VWX48_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9171633.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4100..4990
                     /locus_tag="VWX48_000990"
     CDS             4100..4990
                     /locus_tag="VWX48_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9171634.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5019..6635
                     /locus_tag="VWX48_000991"
     CDS             5019..6635
                     /locus_tag="VWX48_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9171635.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNVNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6645..7964
                     /locus_tag="VWX48_000992"
     CDS             6645..7964
                     /locus_tag="VWX48_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9171636.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMVFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8172..8244)
                     /locus_tag="VWX48_000993"
     tRNA            complement(8172..8244)
                     /locus_tag="VWX48_000993"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8209..8211),aa:Lys,seq:ctt)
     gene            complement(8509..9780)
                     /locus_tag="VWX48_000994"
     CDS             complement(8509..9780)
                     /locus_tag="VWX48_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU9171637.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFNFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10050..10289
                     /locus_tag="VWX48_000995"
     CDS             10050..10289
                     /locus_tag="VWX48_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171638.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10454..10633
                     /locus_tag="VWX48_000996"
     CDS             10454..10633
                     /locus_tag="VWX48_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171639.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10770..10949
                     /locus_tag="VWX48_000997"
     CDS             10770..10949
                     /locus_tag="VWX48_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU9171640.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            10986..11438
                     /locus_tag="VWX48_000998"
     CDS             10986..11438
                     /locus_tag="VWX48_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU9171641.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11729..12199
                     /locus_tag="VWX48_000999"
     CDS             11729..12199
                     /locus_tag="VWX48_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU9171642.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     SLFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12218..13321
                     /locus_tag="VWX48_001000"
     CDS             12218..13321
                     /locus_tag="VWX48_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU9171643.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERATTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNFWFPRL"
     gene            13287..13715
                     /locus_tag="VWX48_001001"
     CDS             13287..13715
                     /locus_tag="VWX48_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9171644.1"
                     /translation="MELEISGFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13853..14803
                     /locus_tag="VWX48_001002"
     CDS             13853..14803
                     /locus_tag="VWX48_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU9171645.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            14805..15548
                     /locus_tag="VWX48_001003"
     CDS             14805..15548
                     /locus_tag="VWX48_001003"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU9171646.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15559..17355
                     /gene="pepF"
                     /locus_tag="VWX48_001004"
     CDS             15559..17355
                     /gene="pepF"
                     /locus_tag="VWX48_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9171647.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNDLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            17601..17930
                     /locus_tag="VWX48_001005"
     CDS             17601..17930
                     /locus_tag="VWX48_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171648.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDGGLDKEIDKIGLPTLERSLGRLFMQLSCLTMPTS
                     NRFFIRN"
     gene            17885..18391
                     /locus_tag="VWX48_001006"
                     /pseudo
     CDS             17885..18391
                     /locus_tag="VWX48_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963306.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
     gene            18502..19170
                     /locus_tag="VWX48_001007"
     CDS             18502..19170
                     /locus_tag="VWX48_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU9171649.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEK"
     gene            complement(19195..19464)
                     /locus_tag="VWX48_001008"
     CDS             complement(19195..19464)
                     /locus_tag="VWX48_001008"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171650.1"
                     /translation="MLKAVFEVIDKTDEVSSKHCFEVADRTDEVSLKHCFEVADRTDE
                     VSLKHCFEVVDRTDVVSNHTYGKVKLTWFEEIFEEYHTKKPCSSR"
     gene            complement(19514..20047)
                     /gene="queF"
                     /locus_tag="VWX48_001009"
     CDS             complement(19514..20047)
                     /gene="queF"
                     /locus_tag="VWX48_001009"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU9171651.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(20352..20666)
                     /gene="trxA"
                     /locus_tag="VWX48_001010"
     CDS             complement(20352..20666)
                     /gene="trxA"
                     /locus_tag="VWX48_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9171652.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(20683..20904)
                     /locus_tag="VWX48_001011"
     CDS             complement(20683..20904)
                     /locus_tag="VWX48_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9171653.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(21003..21383)
                     /locus_tag="VWX48_001012"
     CDS             complement(21003..21383)
                     /locus_tag="VWX48_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9171654.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(21526..22479)
                     /locus_tag="VWX48_001013"
     CDS             complement(21526..22479)
                     /locus_tag="VWX48_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9171655.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREKKIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(22547..23754)
                     /gene="sstT"
                     /locus_tag="VWX48_001014"
                     /pseudo
     CDS             complement(22547..23754)
                     /gene="sstT"
                     /locus_tag="VWX48_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            23893..24453
                     /locus_tag="VWX48_001015"
     CDS             23893..24453
                     /locus_tag="VWX48_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU9171656.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            24510..25408
                     /locus_tag="VWX48_001016"
                     /pseudo
     CDS             24510..25408
                     /locus_tag="VWX48_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
     gene            25360..25950
                     /locus_tag="VWX48_001017"
     CDS             25360..25950
                     /locus_tag="VWX48_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU9171657.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            25953..27059
                     /gene="yqeH"
                     /locus_tag="VWX48_001018"
     CDS             25953..27059
                     /gene="yqeH"
                     /locus_tag="VWX48_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU9171658.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSNALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            27274..27585
                     /gene="yhbY"
                     /locus_tag="VWX48_001019"
     CDS             27274..27585
                     /gene="yhbY"
                     /locus_tag="VWX48_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU9171659.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27637..28266
                     /locus_tag="VWX48_001020"
     CDS             27637..28266
                     /locus_tag="VWX48_001020"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU9171660.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            28266..28859
                     /gene="yqeK"
                     /locus_tag="VWX48_001021"
     CDS             28266..28859
                     /gene="yqeK"
                     /locus_tag="VWX48_001021"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU9171661.1"
                     /translation="MAYQDYINCSREVLLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRHQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            28860..29360
                     /locus_tag="VWX48_001022"
     CDS             28860..29360
                     /locus_tag="VWX48_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9171662.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            29373..29726
                     /gene="rsfS"
                     /locus_tag="VWX48_001023"
     CDS             29373..29726
                     /gene="rsfS"
                     /locus_tag="VWX48_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU9171663.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            29829..30575
                     /locus_tag="VWX48_001024"
     CDS             29829..30575
                     /locus_tag="VWX48_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9171664.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFSMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            30585..31682
                     /locus_tag="VWX48_001025"
     CDS             30585..31682
                     /locus_tag="VWX48_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU9171665.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIAYLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARESDLPEGIHVLGFTEKGRQHLKYLKGQVSLVSRIGKEPWDV
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
BASE COUNT         9713 a         5789 c         7074 g         9397 t
ORIGIN      
        1 ctgtattcac gccctcaata gacggtaaaa taagaaaatt gtttatatat tgtctccgta
       61 gtgttattat acgaaataaa agattttagg aaaagtcgtt atatcatgct atacctattc
      121 tttgtggtat aattgcaaga ggtttaatcc gataatttat aaagagagaa agatattcat
      181 gagagattta ttatctaaaa aaagtcatag gcaattagaa ttattagaat tattatttga
      241 acataaacgt tggtttcatc gttctgaact agcagagtta ttaaattgta cagaacgtgc
      301 agtcaaagat gatctatccc atgttaaatc tgcttttcct gacttgattt ttcattcttc
      361 tactaatggt atacgcatta ttaataccga tgatagtgat attgaaatgg tttaccatca
      421 tttctttaaa cattcaactc atttttcgat tttagaattc atcttcttta atgaaggttg
      481 tcaagctgag agtatttgta aagaatttta tatcagttca tcttcgctct atcgtattat
      541 tagccaaatc aataaagtga ttaaaaggca atttcaattt gaagtcagtc tgacccctgt
      601 tcaaatcatt ggaaatgaga gagacattcg ttactttttt gcacaatatt tttcagaaaa
      661 atattatttc ctagaatggc catttgaaaa tttttcatca gagccactat ctcaattgtt
      721 agaattggtt tataaggaaa caagctttcc aatgaatttg tcaacgcata gaatgctaaa
      781 gttgctccta gttacgaacc tatatagaat aaagtttggt cattttatgg aagtagataa
      841 agattctttt aacgaccaaa gtttggattt tttaatgcag gcagaaggaa tagaaggtgt
      901 tgctcagagt tttgaatcag aatacaatat ctctttagat gaagaagttg tttgccaatt
      961 atttgtgtct tactttcaaa aaatgttttt catagatgaa agtctcttta tgaaatgcgt
     1021 aaaaaaggat agttatgttg aaaaatctta ccatctattg agtgatttta ttgatcagat
     1081 ttcagtcaag tatcagattg aaatggagaa taaggataat ctgatttggc atctgcataa
     1141 taccgcacat ctgtatcgtc aagagttgtt tactgagttt attttatttg atcaaaaagg
     1201 gaatacaatc aggaactttc aaaatatttt tccaaaattt gtttcagata taaaaaaaga
     1261 gctttctcac tatttagaga ctcttgaggt ttgttctagt tcaatgatgg taaatcatct
     1321 atcttatacc ttcatcactc ataccaaaca tttggtgatt aatttgctac aaaatcagcc
     1381 taaactaaag gttttagtta tgagtaattt tgatcagtat catgcaaaat tcgttgcaga
     1441 gacactttct tattactgta gcaataattt tgaactggaa gtttggactg aattagaatt
     1501 atcaaaggaa tctttagaag attcatctta tgatatcatt atttctaatt ttattattcc
     1561 tcctattgaa aataagagac tcatctattc aaataatata aacacggtct cactcatata
     1621 tttgttaaat gccatgatgt ttattcgatt agatgagtaa ccaaaaataa caaaaaaacg
     1681 ctatttcgcg tttgaactgt acctcaaaag ttagacagaa aaaatctaat ttttggggtg
     1741 tttttgttaa gaaaagacct tcaatcattt aagcaaaatg tacatctaga tttatagccc
     1801 tctaaaactc ttgctttttt tgtagaagat acaaaaaagc cataaaacca aggcttttcc
     1861 tgttttatgt agatgtttac acatgaaaat tgaagtattt tcaaaagcta attggagtga
     1921 ttttattcat gatgggataa atgatctggc caaaaatgat tgagaaatag ttgcttaaaa
     1981 agcatttgca tgatactata tattgaaagg aggtgataat atggtagaac aaagaaaatc
     2041 aattaccatg aaagatgttg ctttagaagc aggagttagt gttggaactg tttcacgtgt
     2101 aattaataaa gaaaaaggca ttaaagaagt aactttgaaa aaagtggaac aagcgattaa
     2161 aactttgaat tacattccag attactacgc tagaggaatg aaaaaaaatc gaacagaaac
     2221 gattgcaatc attgtaccaa gtatctggca tcccttcttt tcagaatttg ctatgcatgt
     2281 ggaaaatgaa gtctataaga gaaataacaa attactctta tgttctatca atggtacaaa
     2341 tagagagcaa gactatctgg agatgttgcg tcataataaa gttgatggag tggttgccat
     2401 tacctatagt ccaattgaac attacttgac gtcaggaatt ccctttgtta gtattgaccg
     2461 cacatactca gatattgcca ttccttgtgt ttcatcagat aatgatgcag gtggaagaga
     2521 agcagctaaa caattaatta gtaaaggatg tcagcattta gcctttgtgg gcggacataa
     2581 tacaaccatt aatgaaacca aacgtcgtag aatttcattt gaaaagtatg tccaagagca
     2641 taaaatacct cttagtattt ttgatttgga tgagacagtt actgactatt atggaaagct
     2701 agagagtttc ttggaagaaa attcttctat agatggaatt tttacaatca acgattttac
     2761 agctttggat gtgattgaaa tactaaaaaa aaatggcaaa cgtattcctc atgatgtcca
     2821 aattattgga tacgatggaa ttaaaatggc tggagataga gattatctac tttcaactat
     2881 tgaacaacca ttggaagaaa tggcaaaaga agcggttcgt attttgtttg atataattga
     2941 tggaaagact gttaatttgc agacaatcct accagtaaaa tttgttgaag gaaaaacaac
     3001 aaaaaatgaa aataagtctt gacagaaagc gctatcaatg atagaatgaa ttcagataaa
     3061 aagatttatt tttaaaacaa aaatgaaacg tttcaaaaag agaaatgaag agacagcgtc
     3121 aagcgctatc ttttctagaa aaaaatgaaa cgtttcaaaa aggaggttgc tatgaatagc
     3181 aaagcgaagc aagtttctct ttgggaaaga atcaagaaac aaaaactctt gttattgatg
     3241 actgtccccg gtttagtttt aacctttatc tttaaataca tccctatgta tggggtttta
     3301 atcgcattta aagattacaa tcctttaaaa ggaattttag ggagtgattg gattggtttt
     3361 tctgagttta caaaattcat atcctctccc aactttggta tcttgttagc caacacatta
     3421 aaattaagta tctatggttt attgcttggc tttttaccac caatcattct tgctattatg
     3481 ctcaatcaac tcttgagtga aaaagtcaaa aaacgaattc agctcatttt atacgcacca
     3541 aactttatct cagtcgttgt tattgtcggt atgattttcc tcttcttttc agtgggagga
     3601 ccaatcaaca attttctttc tatgtttgga atgaaggctg acttcttgac aaatccagac
     3661 ttctttagac ccttatacat ctttagtggt atctggcaag gaatgggctg ggcttcaacg
     3721 ctctacacgg caacattggt aaatgtagat ccagccttag tagaagcagc ccgactggat
     3781 ggagccaata tcttccaacg aatctggcac attgatattc cagctcttaa gcctattatg
     3841 gttatccaat ttgttttagc tgcaggtgga attatgaatg tcggatatga aaaagcattc
     3901 ttgatgcaga catcgttaaa tttgccaact tctgaaatta tctcgacata tgtctataaa
     3961 gttggtcttg tatcaggaga ctattcttac tcaacagcgg ttggtttgtt taatgcagtg
     4021 attaacgtag tattgcttgt tgcagttaac caaatcgtta aacgcatgaa taatggtgaa
     4081 ggaatttaag gagggaagta tgaaaaattc gattatggat acaaaatttg atagacgtat
     4141 cttactctta aataaaatca ttattgtctt tatcgttttg atgactttgc ttcctttact
     4201 ttatatcgtc gtagcatcct ttatggatcc taaggttctg gttagtagag ggattagctt
     4261 taatccagcc gattggactg tagaaggtta tcagcgtgta ttcagtgacc aatctattct
     4321 aagaggtttt atcaattctc tactatactc ttttggattt gcagctttaa cagtattgct
     4381 atctgtgttt acagcttatc ctctttctaa gaaagacttg gttggacgtc gttggattaa
     4441 ctacttcttg attgtgacta tgttctttgg tggtggttta gtcccaactt acttgctcgt
     4501 aaaagaattg ggaatgctca atactccatg ggctatcatt gttccaggtg ctgtcaacgt
     4561 ttggaatatt attcttgcta gggcctattt ccaaggattg cctgaagaat tagttgaagc
     4621 tgctgtcatt gatggtgcaa atgatttaca gattttcttc aaaatcatgc ttcctcttgc
     4681 aaaaccaatt atgtttgttc tcttccttta tgcttttgta ggacagtgga actcatactt
     4741 tgatgcaatg atttatatca aggatccaaa cttggaacca ttgcaacttg tacttcgtaa
     4801 aattctcatt cagagccaac caggtcaaga catgattgga gcacaagcgg ctatgaatga
     4861 aatgaaacgt ttagctgaat tgattaaata cgcaactatt gtcatttcca gcttgccatt
     4921 gattgttatg tatccattct tccaaaaata ctttgataaa ggaattatgg ctggttcact
     4981 taaaggataa aaaaagaaaa aataaaagga gttttctcat gaaattcaaa acattctcaa
     5041 aatcagcagt tttgttgaca gctagtttag cagtacttgc agcctgtggc tcaaaaaata
     5101 cagcttcaag tccagattat aagttggaag gtgtaacatt cccgcttcaa gaaaagaaaa
     5161 cattgaagtt tatgacagcc agttcaccgt tatctcctaa agacccaaat gaaaagttaa
     5221 ttttgcaacg tttggagaag gaaactggcg ttcatattga ctggaccaac taccaatccg
     5281 actttgcaga aaaacgtaac ttggatattt ctagtggtga tttaccagat gctatccaca
     5341 acgacggagc ttcagatgtg gacttgatga actgggctaa aaaaggtgtt attattccag
     5401 ttgaagattt gattgataaa tacatgccaa atcttaagaa aattttggat gagaaaccag
     5461 agtacaaggc cttgatgaca gcacctgatg ggcacattta ctcatttcca tggattgaag
     5521 agcttggaga tggtaaagag tctattcaca gtgtcaacga tatggcttgg attaacaaag
     5581 attggcttaa gaaacttggt cttgaaatgc caaaaactac tgatgatttg attaaagtcc
     5641 tagaagcttt caaaaacggg gatccaaatg gaaatggaga ggctgatgaa attccatttt
     5701 catttattag tggtaacgga aacgaagatt ttaaattcct atttgctgca tttggtatag
     5761 gggataacga tgatcattta gtagtaggaa atgatggcaa agttgacttc acagcagata
     5821 acgataacta taaagaaggt gtcaaattta tccgtcaatt gcaagaaaaa ggcctgattg
     5881 ataaagaagc tttcgaacat gattggaata gttacattgc taaaggtcat gatcagaaat
     5941 ttggtgttta ctttacatgg gataagaata atgttactgg aagtaacgaa agttatgatg
     6001 ttttaccagt acttgctgga ccaagtggtc aaaaacacgt agctcgtaca aacggtatgg
     6061 gatttgcacg tgacaagatg gttattacca gtgtaaacaa aaacctagaa ttgacagcta
     6121 aatggattga tgcacaatac gctccactcc aatctgtgca aaataactgg ggaacttacg
     6181 gagatgacaa acaacaaaac atctttgaat tggatcaagc gtcaaatagt ctaaaacact
     6241 taccactaaa cggaactgca ccagcagaac ttcgtcaaaa gactgaagta ggaggaccac
     6301 tagctatcct agattcatac tatggtaaag taacaaccat gcctgatgat gccaaatggc
     6361 gtttggatct tatcaaagaa tattatgttc cttacatgag caatgtcaat aactatccaa
     6421 gagtctttat gacacaggaa gatttggaca agattgccca tatcgaagca gatatgaatg
     6481 actatatcta ccgtaaacgt gctgaatgga ttgtaaatgg caatattgat actgagtggg
     6541 atgattacaa gaaagaactt gaaaaatacg gactttctga ttacctcgct attaaacaaa
     6601 aatactacga ccaataccaa gcaaacaaaa actagaggtt gattatggga gataagaaat
     6661 acacagtaga aaaagccaat cgttttatag cagaaaataa acatctcgtt aatactcaat
     6721 ataagcctga agaacatttt tcagctgaga ttggttggat caatgatcca aatggatttg
     6781 tctattttcg tggagaatac catctctttt atcaattcta tccatatgat agtgtttggg
     6841 ggcctatgca ctggggacat gctaaaagta aggacttggt gacttgggag cacttgccag
     6901 tggcacttgc tcctgaccaa gattatgacc gaaatggttg tttctcaggc tctgccattg
     6961 tcaaggatga tcgcctctgg ctcatgtaca ctggacatat cgaagaagaa accggtgtcc
     7021 gccaagtgca aaatatggta ttttcagatg acgggattca ctttgaaaag atttcccaaa
     7081 atccagttgc aactggatca gacttaccag atgagttgat tgctgctgat ttccgtgatc
     7141 caaaactctt tgaaaaagat ggacgctatt actccgtagt agctgccaaa cacaaggata
     7201 atgtgggctg tatcgttcta ctagggtccg ataacctagt agaatggcag ttcgaatcca
     7261 tctttttaaa agggggagaa caccaaggtt ttatgtggga atgcccagat tacttcgagt
     7321 tagatgggaa agattgcctt attatgtcac ccatgcgtta tcagcgtgag ggagactcat
     7381 atcataacat caactcatcg cttttgttca cgggtaaggt agattggaga gaaaaacgtt
     7441 ttatcccaga atcagttcaa gaaattgatc atggccaaga cttctatgcg cctcaaacat
     7501 tgttggacga tcaaaatcgt cgtatcctga ttgcttggat gcagacatgg gggcgtaccc
     7561 ttccaaccca tgaccaagaa cacaagtggg catgtgccat gactctacct agaattctaa
     7621 gattggaaga tggcaaacta agacaattcc ctgttaaaaa aggccaatat caaatccaaa
     7681 tagataaaga ttgtcattac cacttaggaa atgatataga ttatcttgaa tttggttatg
     7741 acagtaatgc gcagcaagtt tacattgatc gtagccatct tattcaaaaa attctaggtg
     7801 aagaagaaca ggacactagt cgacggtatg tagatattga agctaaagaa ttggaagttg
     7861 ttctagataa aaattccatc gagatttttg tcaatcaagg tgaagcaagc ttgactgcaa
     7921 cttattactt aacggtgcca gctgagctat cacgaattga ttaaaaatta agttatttct
     7981 cctaaagaaa aagttctctt tctaaaatag tggaaagagg actttttgtg ttttgggtat
     8041 ataagcttag tttatggtat ttgtaaaatt ggtgttggat tatgatttaa gctagttttc
     8101 taaagaattt gaaaaaaatt ttatttaagc aaaaaaacct tggttccaag gcttttcctg
     8161 ttgtatttag atgcccccta cagggatcga acctgtgacc cacggattaa gagtccgctg
     8221 ctctgccagc tgagctaagg aggcaaagaa aaaagctgta ttggtgccga aacttcacgg
     8281 tttgtattga acccgcgcaa ttaagcaggt gggcaactcg ctctaactga agctgtttcc
     8341 gtgtgagacg gcctacatgc tgttagaaga cttttgtttc cctaataata caaaaaatag
     8401 tcggtcaaca cttaagtgtg aagtcgtaca ccacagcgtt tctatactta tatgatacca
     8461 ctttttcaaa aaaaatcaag aggaaagtgc aattttttga aaaggatttc agatttttcg
     8521 caaacggtcg atagcttcct ttctttgagc caaagcccgt tcatatttac cagtatcttc
     8581 tgcttggaaa tagtgatgat tacgaatttt ttctggcaga tagtcttgct tgacccaatt
     8641 tccaggatag ttgtgtggat agagatagtc ttgggcattc cccagttcct tgcttccact
     8701 gtagtgccca tcacgtaggt gtcgcggaat aggcaagtgc cctgatgttt tgaggtcagc
     8761 aagtgcctta tccatagcta cataggctga gttggatttt ggagaaaggg ccaaatcaat
     8821 cacgacattg gcaatgagaa tgcgggcttc tgggaaccca atcttctggg cagcatccag
     8881 agcagtcacg gtatgaatct gggcctcagg attggctaaa ccgatatctt cataggcgat
     8941 aatagtcaag cgacgagcga gactaggcag atccccagcc tcaatcaagc gggcagcata
     9001 gtggagactg gcatccacat ctgagccacg gatagacttt tgcagggcag atagaacatc
     9061 atagtgaccg tctccatcct tgtccatagt gatgtagctt ctctgaagac tattttccat
     9121 gatgtctaag gtgatgtggc gaatgccctc gtcattctca ggggtagaga gaacagccaa
     9181 gtccagtgag ttaaaggcag agcgaaggtc tccgtttgta gaggttgcga tgaaatccag
     9241 cgcatcctca tctagttcta ttggaaaatt aaaaccacgt tcagggttac ttagagctat
     9301 ctgcagggcc tctttgacgt cttggttaga cagaggttcc aactcaaaaa tttgaacacg
     9361 gctacgaatg gcaggagtga cggaaaagaa aggattttca gtcgttgctc caatcatgat
     9421 gaccagtcca ctttccaaga gaggcaagag gaagtcttgc ttggtcttat ctagtcgatg
     9481 aatttcgtct agcaatagga cgagaccgcc agaaaattta gcctcttcgg cgatttcttg
     9541 gagtcttttt ttactatcaa ctgtcgcatt gaaagttcga aaggcatact tggtcgttcc
     9601 agcgatggca gaggcaatac tggttttgcc gattccagga gggccatata gaatcatgga
     9661 ggacaggcgg ttggcttcca ccatgcggcg gatgattttt ccaggtccga ccagatgctc
     9721 ctgaccgatg acctggtcga tggttttagg gcgcatgcga agcgcgagat tgtctggcat
     9781 agcagtcctt tctaacgtgg atttgagtag aatgactcat ctactatatc ttactatgtc
     9841 cattctagcc tattagttgt gatatttcaa tggttttgta ataatcaggg agtgagatag
     9901 aatctttttt actatttaat ttaatgagga gaggtatcag catgagagat ttgattttcc
     9961 ttaaagctca aaataggata gttgagccta aagaagtgga agtgctgact tgagaaataa
    10021 tattgctaaa tgtcattgta tgaactataa tgaaaagaga ggtgataagc aatggaaatg
    10081 atggaccaag tcaggaaatt ttgattttta caaaacaaat tcgtcattgg attcttagtg
    10141 atcaagttat ttcagggaaa agaaaacttt tcttccggga agatactcca aaagagattt
    10201 tagatttgta cgaaaacatt aaatctaaac ttgattttgc ttaccaagaa gttcattcta
    10261 ataatgggtt gaaaaaatat gaaaaataga ataattgatg tttttgaagt agtaaatcgc
    10321 ctccttgtaa taactgttga aaatcctgat ttcgaagact tgagagttaa tcatactcaa
    10381 tgaaaatcaa agagcaaact aggaaactag ccgcaggctg tacttgagta cggtaaggcg
    10441 acgttgacgt ggtttgaatt tgattttcga agagtatcag tttgtaaaaa ttggagataa
    10501 aaaatataga gtacgcagtg gtcctatgat tcattcaact ccgcctcaat ctgtcttaga
    10561 tcgagatact tttacaattg actatacaga tgatgaattg ctcgataaag aagcagtttt
    10621 tactactcat tagaaaaata ggtatgaata aattggcttc ccttagaacc acatctaggg
    10681 gcttttatgt ataatagaat aataagtatc actcctttac aatacgtgta acacgtgtta
    10741 taatggtgtt gtcaggaggt aaaagcgcta tgcctatgac acaaaaagag atggttaaac
    10801 tccttacggc ccatggttgg ataaagacta gaggcggtaa aggctcccat attaaaatgg
    10861 aaaagcaagg ggaaagacct atcacaatcc ttcatggtga gctgaataag tacactgaaa
    10921 gagggataag aaagcaagct gggttgtaaa attcagcccc tgctttttga tatggaggta
    10981 gtgaaatgtt agttacgtat ccagctttat tttattatga cgacacagac ggaacagaag
    11041 cgacttattt tgtccatttc ccagattttg aatactcagc tacacaagga gaggggattt
    11101 ctgaggcttt ggctatgggg tcggagtggc tagggataac tgttgcagat ttgatagaga
    11161 gtgatggaga gttacctcag ccatcagata tcaatagctt gtctttaatt gataatgatc
    11221 cttttaaaga tgatgaagat ttcgtgtcaa cctatgacct tgataaatct tttatttcta
    11281 tggtatctgt tgatgtatca gaatacctag gaagtcagga acccattaaa aagactttga
    11341 ccataccaaa atgggcagat aagttgggac gagaaatggg acttaacttt tctcagactt
    11401 tgacagacgc tattgcagat aagaaagttc aagcctaaga ttaagcgtgg tatcgtggta
    11461 atagtcaata aaaaagcacg tccacttgtg ctagttactc gcctattgat tttatagatt
    11521 tattagccct ttcgcgggct ttttatattg atttttatga gaaatgaaga aatcagactt
    11581 ttaagaaaat cactgatacc aagggtttaa atgaggtaat atggtataat taggacataa
    11641 aataattttg tggtaagatg gtagtatcta ttttagcata tttccgagca atcggggcga
    11701 ttaaagagtc gcatagaaag aggacaaaat ggcaacatac ggatttttag atgttttaga
    11761 ggaagagttg gacaagaact ttccctttga ctttgagatt agctgggaca aacgcaacca
    11821 tgcggtagaa gtgagttttc tattggaagc gcaaaatgct gcaggtgtgg agatggtgga
    11881 tgaagacgga gaggtttcat cagatgacat tctttttgag gaagcggtcc ttttctacaa
    11941 tcctgccaag tcaacagtca atgaggaaga ctatttgact gttattcctt acctgcctaa
    12001 aaaaggattt tcccgtgaat ttttagctta tttttcgctt ttccttaaag atactgctga
    12061 ggttgggcta gatgtcctca tggacttttt ggaagaccca gaagcagagg aatttatcat
    12121 ggaatggaac caagaagtct ttgaagaagg aaaagttggc ttggaagagg gagaatttta
    12181 tccttatccg agatactagg agttggttgg aggtgttatg aagaaaattg ggacttattt
    12241 ggtttatgtg ctagctgttg tctttattat gctagctttt gcttgtggaa caatcgcatt
    12301 tgcagagttg gggtattccg cagttttagc ctttactttt ggttatgcct tcgctcttct
    12361 aagcatgtat ttaattttta ttcttcatga gctgggtcat gctttttgtg gctacttgac
    12421 aggctatcgg ctggtggctt ttggattagg acattttatt ttgaccaaaa agtcaggcag
    12481 gtttcatctt agtagaacag ccattctgaa aaatgttggt gctcaataca ttggtttaaa
    12541 agaggatgaa agcgatcaaa gaatcatcct gatgctttca ggaggcttga tggttcatct
    12601 cggcttgata ttattggcga tagtgtttgg atttttgaca agaagctggt attttgcagg
    12661 gacttggatt tttcttaatt tatctttctt cctaaataac attttgccag tcgacatcac
    12721 cgatggagca aaaatttggg aattactaca acaccctgaa aataccaaat acgcctacct
    12781 ggtattgaga cattctgctc aaactttgct ggctcctcaa gaatatgatt tgaaagactt
    12841 tgttcaagca gttcctgagg atgcacgagg gagttttgcg gatggtgtat taggtatgca
    12901 aggtgaagtt tccattttgg aagggaagga agaagtagct aaacagcagt ttcaagcatt
    12961 acttgagagg gcaactactc cgatgatgca gacagttgcc caactatccc tgcttcatat
    13021 cgccttgttg gaaggagatt ttgagcaagc ggagcaatat gctagtattc gacaggtcaa
    13081 atcgtttctg tctctcaaac tgtccaatct tcaagtgata caagcctggt atcaattaaa
    13141 ggtgaagaaa gatgtagatc gaactcgtaa ggctctcaag attgctagac agaaaatgga
    13201 tagtagtcga atgttgaggg acgagaaacg ctattatgaa aacttgttag ccgagctgga
    13261 aaaggaaatg ttagaaggaa ctgaagatgg aactagaaat ttctggtttc ccaggctgta
    13321 agattgcttt gttttgtggg gataagctct tgactatctt acgtgatgat aaggcaagta
    13381 ttccctgggc caatatgtgg gaactgccag gtggtggacg tgaaggtgat gaaagtcctt
    13441 ttgagtgtgt agcgcgtgaa gtttatgaag aactgggcat tcatctgact gaagattgtc
    13501 tgctttggag taaggtttac ccaagtatgc tttttgcaga caaacagtcc gtttttctag
    13561 ttggtcagtt gacacagaac cagtttgaca gtatcgtatt tggagatgaa ggacagggct
    13621 atcagctgat gaatgttgag gaatttctta gttccagtca agttgtgcct cagttgcaag
    13681 agagattaaa agattattta aaagtaagtg attagaaagg atggttcagt taaatttcta
    13741 aactgaaccc gccctaaaca ctgtgccaaa aagataaact tctcttagac acaagcgtct
    13801 tcagagaatt tcctattttg gttttgtgtt ttacgggctt ggtatcttaa taatggaaac
    13861 atggcaagag ttaaaagtta cagtgaagcg tgagggagag gagttggttt ccaatctctt
    13921 gattgagctg ggagcgcaag gagtcgcgat tgaagacagc atggactata tgggaaatgt
    13981 ggatcgtttt ggcgagattt tcccagaggt ggagcagcaa gaagaaatcg tagtgacagc
    14041 ctactaccct gacacggtgg atgtgacagt ggttgaggcg gacttgcagg ctcgcttagc
    14101 agaattgacg gattttatgg atttgggtga agtcaagatg gggacgactg ccttggctga
    14161 ggaagactgg gcagacaact ggaagaaata ctatgagcca gctcgtatca ctcatgattt
    14221 gaccatcgtt ccctcttgga cagactatga ggcgactgcg ggagaaaaaa ttatcaagct
    14281 agatcctggg atggcttttg gtactgggac ccatccaact accaagatga gcctctttgc
    14341 cttggaacag gttcttcgtg gtggcgagac agtgctagat gtggggactg gttcaggggt
    14401 tctctccatt gctagctcgc tacttggtgc caaggaaatc ttcgcctatg acctggatga
    14461 tgtggcggtt cgtgttgctc aggaaaatat tgaacttaac cctggaatgg aaaatatcca
    14521 cgttgctgct ggagacttgc ttaagggtgt tgagattgag gcagatgtga ttgtagctaa
    14581 tatcttggcg gatattctca ttcatctgac agacgatgcc tatcgtttgg tcaaggatga
    14641 aggctacctg atcatgagtg gcattatcaa ggacaagtgg gacatggtgc gcgagtcggc
    14701 tgagtcagct ggatttttcc ttgaaaccca catggttcaa ggggaatgga atacctgtgt
    14761 ctttaagaaa accaaggata tctctggtgt gattggaggc tagcatgcag cagtattttg
    14821 taaaaggcag tgctatctct cctgtcacta tcgaggacaa ggaaaccagt aagcatatgt
    14881 ttcaggttat gcgcttgaaa gaagaggatg aggttacctt agtctttgat gatggcatca
    14941 agcgcttggc gcgcgtgctg gatatggaaa atcgtcagtt tgagttggtc caagaattaa
    15001 atgacaatgt ggaactacca gtccaagtga ccatcgcatc tggatttccc aagggagaca
    15061 agctggagtt catcgctcaa aaagtaaccg aactgggtgc tagccaaatc tgggcctttc
    15121 ctgcagactg gtcagttgcc aagtgggatg gcaagaaatt gggtaaaaaa gttgaaaaac
    15181 tagaaaaaat tgcccttgga gcagccgagc aaagcaagcg taatattgta ccaagtatta
    15241 aacttttcga gaaaaaagca gattttctag ctcagctgga ccagtttgac tttatcatag
    15301 tagcctatga agaatcagct aaagaaggag aagccgctgc gcttctgcaa gcagtcactg
    15361 gtcttgaaac aggagccaaa ctgctcttta tctttggtcc agaaggcggt ctctcacctg
    15421 cagaaatcga aagttttgaa gctaagggag ccgttttggt aggcctaggt cctcgtattt
    15481 tgcgagcaga aacagcaccg ctttacgcct tatcagccct tagtgtttta gtagaattag
    15541 agaaataaga ggaagaaaat ggaacaaaaa caccgttcag aatttccaga gaaggaactc
    15601 tgggacttaa cagccctata ccaagaccgt gaggatttct tgcgtgcaat cgagaaagct
    15661 cgcgaagaca tcaaccagtt tagccgtgat tacaagggca atcttcacac ttttgaggat
    15721 ttcgagaagg cctttgcgga attggaacag atctacattc agatgagcca tattggcaac
    15781 tatgctttta tgcctcagac gacggactat agcaatgacg aatttgccaa tattgcccaa
    15841 gctgggatgg aatttgaaac agatgccagc gtagccttga ccttctttga cgatgccttg
    15901 gtggcagcag acgaggaagt cttggaccgt ttgggtgaat tgcctcactt gacggcagct
    15961 attcgtcagg ccaaaatcaa aaaagcccac tatctagggg ctgatgtgga gaaggccttg
    16021 accaatctcg gtgaagtttt ctacagtccg caggacattt atactaagat gcgagctggg
    16081 gattttgaaa tggctgactt tgaagcccat ggcaagacct acaaaaacag ctttgtcacc
    16141 tatgagaatt tctaccaaaa tcacgaggat gctgaggttc gtgagaaatc cttccgttcc
    16201 ttctcagagg gacttcgtaa gcaccaaaat acggctgcag cagcctatct ggctcaggtc
    16261 aagtctgaaa aactcttggc tgatatgaag ggatatgact ctgtctttga ctatcttcta
    16321 gctgaacaag aagtggaccg tgtcatgttt gaccgccaga ttgaccttat catgaaggac
    16381 tttgcaccag tcgctcagag atacctcaag catgttgcca aggtaaatga tcttgaaaag
    16441 atgacctttg cagactggaa attggacttg gacagcgccc tgaatcctga agtgactatt
    16501 gacgatgcct atgatttggt catgaagtcg gtagaacctt tggggcaaga atattgtcag
    16561 gaagttgctc gttaccaaga agagcgctgg gtggactttg ctgctaacag tggcaaggat
    16621 tccggtggtt atgcggcgga cccatatcgc gtacaccctt atgtactcat gagctggaca
    16681 ggccgtttga gcgatgtcta taccttgatt catgaaatcg gacattctgg tcaattcatc
    16741 ttttcagaca atcaccaaag ctatttcaac gcccacatgt cgacctatta tgttgaagca
    16801 ccgtcaacct tcaatgaatt gctactcagt gattacttag agaaccagtc taatgaccca
    16861 cgtcaaaaac gcttcgctct ggctcatcgc ttgacagaca cctacttcca taatttcatc
    16921 acccacctct tggaagccgc cttccagcgt aaggtgtata cattgattga agaaggggag
    16981 acctttggag caagcaagct caacagcatt atgaaggaag ttttgacaga tttttggggc
    17041 gatgccattg aaatcgacga cgatgcaact ctgacttgga tgcgccaagc tcactactat
    17101 atgggcttgt atagttacac ttactcagca ggactagtta tctcgactgc tggttacctt
    17161 catctaaaac attctgaaac tggagctgaa gactggctca atctcctcaa atcaggtggt
    17221 agcaagacac cacttgagtc agccatgatt atcggtgctg atatttcaac agacaaacca
    17281 ctccgtgata ccatccaatt cttgtctgac acagttgacc agattatctc ctatagtgct
    17341 gagttgggag agtaggggaa tagaaaaatt ttttagaatg atgtttatgg gcttgttaag
    17401 cgtcattcta tttgtcttag ttgtagctat tttcaaaaat gtcgttgaag gtcgtgatgt
    17461 taaatttgaa cttactgtag aactggtatt gatagttatt tacgtcattt tatatcagat
    17521 tgtatttaat tgagaattca atattgagtc atttaagact gcctttttga acagttgcta
    17581 gaaatgtaga ggtattgacc atgtatcaag atttactaag aaaaatagca gaagaaaaac
    17641 caaattataa ccaggaggaa atccagtggt tgcttgatca tttgggagat ccttctccag
    17701 aaattcgtga tgaccttgtt tttacaagct ttgctagagg gattcaggaa gagctattta
    17761 cacaggagca atttcatttc attgctgaag gggtttcatc tgatggaggg ttagataaag
    17821 agattgataa gataggcctg ccaacacttg aacgttcttt agggcgctta tttatgcaac
    17881 tctcttgtct gacgatgcca accagcaatc ggttttttat caggaattaa atgcaggatt
    17941 tcgtaatgac ctttcaaatc aaggcttgca ctatctttca aaagaaaagg atacaacagg
    18001 tttctcaagt cagtatggtt gggttcacgc ttttgcacat ggagccgatt tactgacaga
    18061 ggtggtttgt catccagact ttcctaaaaa cagagttcat gaagtatttg atatacttgg
    18121 ccaactattt aaaaggatgt cgattcgctt tacagatgat gaggattggc gtttagcaag
    18181 agtgatctat gaacctattt tataagggaa gttggagcaa gaacaagtag cttcttggat
    18241 aaaaactgtt gattttccga tagaagaaag ggaggatttt tacaaatttt ccaactttag
    18301 atcctgtctg gtggaagtct atgtccaact tgaccagaga aatagtttac aagatgagtt
    18361 gaaagaagct atccagtctt ttcaatacta gagattagct aatagttcta tgattttcaa
    18421 aaaatttcca atcaattttc ttgaaaccct ttcctacttt tgatagacta gtatctagtt
    18481 tttgaaaaaa ggagaaagaa aatgaaaaaa tttgttgctg agttaatcgg tacgttcatg
    18541 cttgtgttcg ttgggacagg agctgttgtt tttggaaatg gtcttgatgg ccttggtcac
    18601 cttggaatcg cctttgcctt tggtttggca atcgtggtgg cagcctactc aatcggaact
    18661 gtttcaggtg ctcacttgaa cccggctgtt tcgattgcta tgtttgtaaa caaacgtttg
    18721 tcatcttcag aacttgtaaa ctacatcctt ggtcaggttg ttggagcttt catcgcttct
    18781 ggcgcagtct tcttcctctt ggctaattca ggtatgtcaa ctgctagtct tggtgaaaat
    18841 gccttggcaa acggtgtcac tgtctttggt ggtttcttgt ttgaagtcat tgcaactttc
    18901 ttgtttgtct tagttattat gactgtgact tcagaaagta agggcaatgg cgcgattgct
    18961 ggtttggtaa tcggtttgtc attgatggcg atgattcttg tcggattgaa gattactgga
    19021 ctttcagtaa acccagctcg tagcttggca ccagctgtct tggtaggcgg cgcagccctt
    19081 caacaagttt ggattttcat ccttgcacca atcgctggtg gagttcttgc agcccttgtt
    19141 gcaaaaaatt tccttggaac agaaaaataa ttgaaactca aaaagccttg ctcctcatct
    19201 tgaggaacag ggctttttcg tatgatactc ttcgaaaatc tcttcaaacc acgtcagctt
    19261 taccttgccg taggtatggt tactgactac gtcagttcta tccacaacct caaaacagtg
    19321 ttttaagctg acttcgtcag ttctatctgc aacctcaaaa cagtgtttta agctgacttc
    19381 gtcagttcta tctgcaacct caaaacagtg ttttgagctg acttcgtcag tcttatctat
    19441 aacctcaaac actgctttga gcaacctgcg gctaacttcc tagtttgctc tttgattttc
    19501 attgagtatg actttagcgg ttgtcaattt tctctggata aaggtcgtgt tggaagaggc
    19561 gttgttctgc caagtcctca tacttagttc cttgcttacc gtagttgtag taggggtcga
    19621 ttgaaatgcc accgcgcgga gtgaattttc cccagacttc taaatagcga gggtctagca
    19681 agttgaccaa gtctttcccg atggtgttga tacagttttc gtggaaatct ccgtgatttc
    19741 ggtagctaaa tagatatagt ttgagggatt ttgactcgac acagagcttg tcaggaatgt
    19801 aggaaatatg aatcgtcgca aagtctggct gagcagtgat ttgtcccagc agagacatat
    19861 cgaggatatg gtgacgaatg ccctgttcct tagcgatttc tctagcaatt tgaatttcga
    19921 ggtgatgacg ttggccgtag gcaaaggtga cagcttcgac tgtttcatag tgttgcataa
    19981 cccagaaaag gcaggttgtt gaatcttgac caccactaaa gacgaccaag gctgattgac
    20041 gtttcatagt actccttcca aaatgggaaa tgttcagagc atgcaaaaag ctcctattag
    20101 ggagctaaaa aataccaaat cgagtttttt tagcgatggc atatcccaaa catcgtaata
    20161 ttctacttat atagtaaaat gaaataagaa caggacaaat cgatcaggac agttaaatcg
    20221 atttctaaca atgttttaga agtagaggtg tactattcta gtttcaatct actatagtct
    20281 agcatatttt ttgaaaaatg gcaaagggca agaaaaaaga gaccaaagaa agtacttggt
    20341 ctctcgtttg attagctcaa ttcagcaatg atggccttga tttgttctgc tgtgtgaaca
    20401 cctgcaactt gtttgacaac ttggccgtct tttttgaaga gaagagttgg aatagacatg
    20461 attccaaaag cacgagctgt gtttggattt tcatcaacgt ccattttaac gattttcaag
    20521 acatcttctg aaagttcttc agacaatttg tccaagattg gaccttgcat acgacatgga
    20581 ccacaccaag ttgcccagaa gtctactaag accaaaccat cttttgtttc ttgttcgaat
    20641 gttgcatctg taattgcttt tgccattgta tttctccttt ttttagttat attggcttaa
    20701 atcttgtttc atgagataga agaagatatc tccataagtc ccatggtagt ccaaattatg
    20761 acccttgtaa gttaattttt ggacagggta gtagtctgcg acgccgataa ggcaagcttg
    20821 ttgcgaacgt tcaaagtctt cataagactc gaaagtcaca gttctttcgt tcttgctggc
    20881 atctatatag gtaatttcaa tcatatttaa aactcctttg tttaatgcta actttatttt
    20941 actccttata aaagagaatg tcaagaaaaa tgattgcgca cgcaactttt tttaaaatca
    21001 tcttaaatca agaaatccaa acctgcttcc aagctttctt cgacagtctt ttgtagcgag
    21061 gccagtgtct tttgcccatc atttgtcagg cagataaaac tagagcgtct atcttgatgg
    21121 caacacatgc gactgagtag accgcaattt ttagcttcca agcgagccac catcctagaa
    21181 actgcgctcg ggctcagatg aagtttatct ggcaggtcaa tctggcgtag agatttttct
    21241 tcagccaagt ccagatagta gagcaggtag aactctttca aggtcagact ttgctcgctc
    21301 tgttgggcaa tggtctcttc caagagactt tcaatttctt tctgacgccg attgaagtca
    21361 aaccattttt ccaaataggt catagtgtct cctttctttt tagagtcata aatagaagaa
    21421 agtccattaa cgggcagtct ctgcgtcaca agatgattgc gcatgcaata attatactac
    21481 ttttcaagaa tgctggcaag ctctgttttt tagtggtttt attttttact gtctatattt
    21541 ttggtaaaaa tcaactttta cttggatgaa ggttttggct tcacgtagga gttgaagaag
    21601 ggtggcgcgg gtttcaaact cttctcttgt cttgggcaga ctgcggttcc ggaagacttc
    21661 cagataacgt tcaatttcat ctagcaaatc agaagcagga ttggtctggc tcagttgacc
    21721 tgcaattttt gaaaagagtt gcgctaagat caggctttca ctggcggcaa ggtgacaagt
    21781 gttaatctgt tgggccatgt ttctcaggat acgactttgt cgttgtctca tctcaaagta
    21841 gtggatatgg tagtcggtct ggtgaaagag gtggtcagag tgatccaaat agaccagtct
    21901 gagggcttct ttcaaaagcg tgtctaattc tgctaccagc tgtgctcggt tgcgtccgtc
    21961 tcctctggat aaatagtatt tgaagcgctg gaggatatct tttaactttt cttccaccag
    22021 cgtgtggtag tgctggattt tcttttctcg tgaaggcatg tagagattga ccagtaaagc
    22081 aaatcctgta ccgatagcaa agagaaggaa ttcattgact agaaggtctg gagaggttga
    22141 ctcttgaacc aagagatggc taaccaaaac agtgcttggt gtgataccaa tttcccagcc
    22201 catcttgtag gctaaaggaa cgtagaaggc cagatagagg ccgagactcc agatatgaaa
    22261 tccgctcaaa tgaaaagcta gaacaccgat agccagagct agaagcatag aaaaaagacg
    22321 attgcgagcc agttttaaag tacttctacg cgtatcagat aggctcaaga gagcgataat
    22381 tccagccgaa actgctgacg aaagattgag aaaataagca agcaggcagg caagacaggt
    22441 agctaagatg agcttggtcg tacgttggct aatagacata agaatttcct aataagttag
    22501 aataaaagcg taaaagacaa gacatgagca ggcttgcctt gatgagttat tttttacggg
    22561 ttgctgcgta ttcggcaacg gcggtaaaga ggacatctgt agaagagtta agggctgttt
    22621 cacatgagtc ttagatgaca ccaatcacaa aaccaacccc aacaacttgt atggcaatat
    22681 cgttagaaat accgaaaagg ctacaagcaa ctgggataag aaggagggaa cctctggcaa
    22741 tacctgaagc accacaggct aagatagctg ctaccacact gaggacaaag gctgtggcaa
    22801 agtcaacagg aattccaaga gtgttaactg cagcaagggt caaaaggtta atggtaatcg
    22861 ctactccagc catattgata gtagaaccga gtgggataga aacagaatag gtatctgggt
    22921 tgagtccaag gtcatggcag agtttcatgt tgacaggaat gttagccgca gaactacgag
    22981 tgaaaaaggc tgtcacaccg ctgacacgga ggcagttcca aactagaggg taaggattgc
    23041 gtctcataaa gaagaaggca atcaaagggt gaccacaagg gcaacaaaaa gcatagtcgt
    23101 tactaataga accaataaaa taccgtagtt ggtaaggctt ccgactccct tgtcagaaat
    23161 ggttttaaaa acaagaccaa ggcttccaaa tggagccaga ttgatgatcc attcgacaat
    23221 tttagaagtc acgtcagcga tagtttttag caattcttta ctatttttac tggcttctct
    23281 catagcgatt ccaaaaatga ctgcccaaga taagattcta atatagttag cagtaaacag
    23341 ggcgttgact gggctgtcaa ccagtttgag caagaggttg ctgagaacct gcccaacccc
    23401 atctggtggt gcaatttcag tattggcact atttagggta atttcaatag ggacgatgaa
    23461 acttgctagt acagctacaa gagcagcggc gaaagtccct atcataggat atacaagaaa
    23521 acaacagttt tcatattgct atcttgtccc ttttgatgtt ggaaagggca ttggcaacga
    23581 gggcaaagac taggatagga gcaacagctt ttagacctcc aacgaataaa tccccgagta
    23641 gcccaatccc tgagagatta ggaagggtca gtcctaggat tccccacaaa gcataccaat
    23701 caagatacgc ttgacaaggc ttgccttatt ccaagcatga atgattcttt tcataataat
    23761 ctcctttttg tgtagtgatt atgattatag tataaatgat agacaaaatc aagaattttc
    23821 tgtctatttt ttgaatattt atggagaatg agactgatga aaatatggta taatgaaata
    23881 aaggagtttt atatgcaaaa atttattcag gcttatattg aaaagctaga tgtgacaacc
    23941 attatcgaga atattctaac caaggtcatt tctcttttac tgcttttgat tgtattttat
    24001 attgctaaaa aaatgcttca taccatggtg cagagaattg tcaaaccttc tctaaaaatg
    24061 tctcgtcatg atgtcggacg ccaaaaaacc atctcacgtt tactagaaaa tgtgtttaat
    24121 tatacgctat atttcttttt actctactgc attttgtcga ttttaggttt gccagtttct
    24181 agtttgctgg ctggagctgg tattgctggg gtagcgattg gtatgggagc ccaaggcttt
    24241 ctgtctgatg tcatcaatgg ctttttcatc ctctttgaac gtcaactgga tgtgggagat
    24301 gaggtcgttc tgacaaatgg accgattact gtatcgggta aggttgtcag tgtgggaatt
    24361 cgtacgacac agcttcgtag cgaggagcaa gcccttcact ttgtccctaa ccgaaatatc
    24421 acagttgtta gcaatttctc acgcacagac tagacctgtt attttaagta atttgtggta
    24481 caatagaggg agtttaataa ggagaaaaga tggttttaga aaagcagttg ggcaatggtt
    24541 gtacctggat agacctagac ctaggaaagt tgaataaact agaagacctt tctgaaattt
    24601 acggtttgga caaggaaacc attgaatacg cactggatag aaacgagcgc gcccacatgg
    24661 actaccaccg tgaaagtggg acggttacct ttatctataa tgtcctagac gtaaaaaagg
    24721 acaaggccta ctatgagact tttcccatga cctttattgt cgagcatcgt cgcctgatta
    24781 ccattagtaa taccaagaac gcctatgtca ttgaacagat gactcgttat ctggagagcc
    24841 atgacacgct ttcgatttat aagtttctct ttgccagtct ggaaatcatc agcaatgcct
    24901 actatcctgt cattgagcag atggacaaga gtagggatga ggtcaatgac ctcttgcgcc
    24961 agcgaactac caagaaaaac ctctttgccc tgtctgattt ggagactggt atggtttatc
    25021 taacggcagc tgccaaacaa aatcggattt tgttagagca tattcaaggt catgccttgt
    25081 atcgtagttt tgatgagatt gagagagaac agtttgatga tgccatgatt gaggctcatc
    25141 agctggtatc catgacagac ctaatctctc agattttaca gcagctttca gcctcttaca
    25201 acaatattct aaacaataat ctgaatgaca atttgacaac cttgactatc atttcagtct
    25261 tgctagctgt tttggcagtc gtgacaggct ttttcggaat gaatgttccc ttgcctttaa
    25321 ccatgcttgg ctctatatca gtttggctag tgcaggtttg tggattgttt tatccttgtt
    25381 actaaggaaa attgcgaaaa aaagttaaga aaaggagcca gaatggcgat tgaaaattat
    25441 ataccagatt ttgctgtgga agcagtctat gatctgacag tcccaagcct gcaggcgcag
    25501 ggaatcaagg ctgttttggt cgatttggat aataccctca ttgcttggaa caaccctgat
    25561 ggaacgccag agatgaagca atggctacat gaccttcggg acgcgggtat tggcattatc
    25621 gtagtgtcaa ataacaccaa aaaacgcgtt caacgagcag ttgagaaatt tgggattgat
    25681 tacgtttact gggccttgaa gcccttcaca tttggtattg accgtgctat gaaggaattc
    25741 cactatgaca aaaaggaagt ggtcatggtt ggtgaccagc tcatgacaga tatacgagca
    25801 gcccaccgtg cagggattcg gtcaatttta gtcaaaccct tggtccaaca tgactcaatc
    25861 aaaacgcaga ttaaccgaac tcgtgagcgt cgtgttatga gaaaaatcac tgaaaagtac
    25921 ggaccgatta catataaaaa aggaatttaa ctatggaaga aattctctgt attggttgtg
    25981 gagcaaccat tcagacgaca gataaagctg gtcttggttt taccccccag tcggcacttg
    26041 aaaaaggttt ggagactggc gaagtctatt gccaacgctg tttccgtctc cgccactaca
    26101 atgaaatcac agatgtccag ttgacgaacg atgatttcct caagctcttg cacgaggtgg
    26161 gagacagtaa tgccttagtg gtcaatgtca ttgatatctt tgattttaat ggatctgtca
    26221 tcccaggttt accacgtttc gtctcgggca atgatgtcct cttggtagga aataaaaaag
    26281 atatccttcc taagtcagtt aagtctggta agattagcca gtggctcatg aaacgtgccc
    26341 atgaagaagg tcttcgtcca gtcgatgtgg tcctaacttc agcacaaaat aaacatgcca
    26401 ttaaggaagt cattgacaag attgaacact accgtaaggg ccgcgatgtc tatgtggtcg
    26461 gtgtgaccaa cgttggaaaa tcaactctaa tcaatgctat tatccaagaa atcacgggtg
    26521 atcagaatgt catcactact tcacgcttcc cagggacaac cttggacaaa atagagattc
    26581 cgcttgacga cggatcttat atttacgata cgccgggaat tatccaccgc caccagatgg
    26641 ctcactactt gacggccaaa aacctcaagt atgtcagtcc taaaaaggaa atcaagccta
    26701 agacctatca gcttaatcct gagcaaaccc tatttttagg tggtttggga cgctttgact
    26761 ttatagcagg agaaaagcaa ggatttactg ctttctttga taatgaactc aaactccatc
    26821 gtagcaagct tgaaggagct agtgctttct acgataagca cctgggaact cttctgacac
    26881 caccaaatag caaggaaaaa gaagatttcc caaggctagt ccagcatgtc tttaccatta
    26941 aagataagac agacctagtc atctcaggcc taggctggat tcgtgtaaca ggcatagcaa
    27001 aagtcgccgt ctgggcacca gaaggcgtcg ccgtcgtcac acgaaaagca attatttaag
    27061 cacagaaagg aaagggttgt ctgaatttgg gcgagcaagg cgagccccat agagaatact
    27121 tttcgctgtg gtgtaagttg gtacaagtga ttgtaccaac tgcggaaaat ttgagacctt
    27181 aggctcaaat tttagtcatg aaagtccgaa ggactttgct gacgtccgtc accacttcag
    27241 aaaagtataa aaagaaactc ttttaaagaa attatgtcat taacatcaaa acaacgtgcc
    27301 ttcctcaaca gccaggcaca caccctcaaa cctatcatcc aaatcgggaa aaatggactc
    27361 aacgaccaaa tcaaaaccag cgtccgtcaa gctcttgatg cgcgtgaatt aatcaaggtt
    27421 actctcttac aaaacacaga tgaaaacatc cacgaagtag ctgaaatttt ggaagaagaa
    27481 atcggtgtgg atacagtcca aaaaatagga cgcatcttga ttttgtttaa acaatctagc
    27541 aagaaagaaa atcgcaagat ttctaagaaa gtcaaagaaa tctaagaccg aaactccaaa
    27601 taactgtttt tatagagaaa taaaggggac tagcctatga caatcgaact attgactccc
    27661 tttaccaagg tagagttgga gccagaaatc aaggagaaaa aacgcaaaca agttgggatt
    27721 ttagggggga attttaaccc tgttcacaat gcccatctca ttgttgcgga tcaagtacgg
    27781 caacagttgg gactggatca agttctgctc atgcctgaat accaacctcc tcacgttgat
    27841 aaaaaggaaa ccatccctga acaccatcgt ctcaagatgc ttgagttggc aattgagggg
    27901 attgacggcc tagtcattga aaccattgag ttggagcgca agggtatttc ctacacctac
    27961 gacaccatga aaatcttgac agagcaacat ccagatacgg attattactt tatcatcggc
    28021 gccgacatgg ttgactatct gcctaagtgg taccgaattg atgaactggt tgacatggtt
    28081 cagtttgtgg gggttcagcg tccacgctac aaggcaggga cttcctatcc agttatctgg
    28141 gtggacgtac cgctcatgga tatctcgtcc agcatggtgc gggacttcat tgcccaaggt
    28201 cggaaaccca actttctcct acctcagcct gtgctagact atatcgagaa ggaagggctc
    28261 tactgatggc ctatcaagac tatatcaact gctctcgtga ggttttgttg gaaaaaatgg
    28321 cagagcttct acctgagaaa cgtctaaccc attgtctagg tgtggagcgt gccgctatgg
    28381 aattagctca gcgctttggt gtagatgttg agaaagcaag tctagcaggt cttcttcatg
    28441 actatgctaa aaagttgtca gatcaggaat ttctagcctt gattgaccgt caccagctag
    28501 accctgacct caaaaactgg ggcaataatg tctggcatgg tatggtcgga atttacaaaa
    28561 ttcaggaaga tttggatttg catgattctg aaattctgcg agccattgaa gtccatacag
    28621 tcggtgctgg tcaaatgaca gacctagata aggtcatcta cgtcgcagac tatatcgagc
    28681 acaatcgagc ctttcctgga gtagatgtgg cgcgtgagat tgcaagtcta tcgctcaata
    28741 aggcggtggc ctacgaaaca gctcgtaccg tggagtatct agctcatcag ggattcccca
    28801 tctatcccca aacccttgaa acctataacg cctttgtgca ctatttgaaa gagaactaaa
    28861 tgaagacggc ttttataatc attgatgttc agaatgtttt agtagaaact gggttccaga
    28921 caaaaagtct attgggaaaa atttcttatt tacaaaacca ggctagaagc aagaatattg
    28981 aaattatcta tgttcaacat attgagaact ctgaagctca aacatcagaa gattggcagt
    29041 tatctgcgct tttaaatcga aaacctgctg aaaaggtctt tcagaagaag tataacagta
    29101 ttttcaaaga aactggctta aaagaatact tggataaaca ggggattgaa aaattagttt
    29161 tatgtggtat gcagacagaa tattgtgtgg atacctctgt caaggttgcc tttgaatatg
    29221 gctatcagct tattgttcca gaaggtgctg tcacaacctt tgatggggat gacattccag
    29281 cagaaacgat taatgaattt tatgaggaca tttgggagga gcactttgca gatgtcctag
    29341 attacaaaca tattttctaa aaagaggatt aaatgaacga aaaagaatta ctagaactag
    29401 tcgtgaaagc ggctgatgag aaacgtgcgg aggatatcct cgcacttgat gtacaagatt
    29461 tgactagtgt gacggactac tttgtcatca ctagctcaat gaatagccgt cagttggacg
    29521 ctatcgcagc taatatccgt gaaaaagtag ctcaagcagg ctttaaaggt agccatgtcg
    29581 aaggcgatgc agctggaggc tgggtcttac tggacctcgg tgctgttgtc gtgcatatct
    29641 tttcagaaga aatgcgtgcc cattataatc tagagaagct atggcatgag gcgaattcag
    29701 tagatatttc agaagctctt gcttagaaga tgaactcagt tgtagtcaac tgggtttctt
    29761 tgcttatttt agaaaaattg atagaaaggt aaagggctag tggtgtttac catggagctc
    29821 ttagtatcat gattatggcg acttatgaaa cctttgcggc tgtctatgat gcggtcatgg
    29881 acgatagttt atacgacaaa tggacgaatt tttctctgcg tcatttgcct aagaccaagg
    29941 agagaaagaa actcttggaa ttggcttgtg ggacaggaat tcaatcagtg cgcttctctc
    30001 aggctggttt tgatgtgact ggacttgact tgagtgcgga tatgttgaag attgcggaga
    30061 agagagcaac ttcagccaag caaaagattg cttttataga aggtaatatg ctaaatttgt
    30121 ccaaggcagg gaaatacgat tttgtcacgt gttattcgga ctctatctgc tatatgcagg
    30181 atgaggtgga agtaggggac gtctttaagg acgtgtacaa tgcgctgaat gaagagggag
    30241 ttttcatctt tgacgtgcac tcgacctacc agacagatga agtattccct ggctattcct
    30301 accatgaaaa tgcggaagat ttttccatgc tttgggatac atatgaggac gaagttcctc
    30361 actccatcgt gcatgagctg actttcttta tcaaggaggc tgacggttcc tttagtcgcc
    30421 acgatgaagt acatgaggag aggacctatg agatcttgac ctatgatatc ttgctggaac
    30481 aggctggatt caagtccttc aaactctatg cagactttga ggataaggag ccaacagaaa
    30541 ctagcacccg ttggtttttt gtggcgcaga agtaggagat tagcatgacc atcacaggta
    30601 ttatcgcgga gttcaatcct tttcataatg gccataaata cctgctggat caggcagagg
    30661 gactgaaaat tgttgccatg tcagggaatt tcatgcagcg tggagagcct gctattgtgg
    30721 ataagtggac aagggcccag atggcgctgg aaaatggcgc agacttggta gtggaattgc
    30781 cctttttagt cagtgttcag gcagctgatt tctttggtca aggagctgtg gatatcttgg
    30841 atcgcttggg cattgatagt ctagtttttg ggacagagga agttcgagat tatcagaaaa
    30901 tcgcttactt atacacagag aaaggtgctg agatggagaa atttgtggaa aatctgcctg
    30961 attccctttc ctatccccag aaaacccaag ctatgtggaa ggaatttgct ggtcttgatt
    31021 tttcaggtaa tacccccaat catgttcttg ctctggccta tgcaaaggcg gttgcaggac
    31081 gaaatatcaa gctgcatccg attcagcgtc agggggcagg ttaccattct gtgaataaag
    31141 atgtggactt tgcctcggcg acagccctcc gtcaacatca gaaggaccaa gatttcttag
    31201 aacgttttat gccttctgtt gccctatttg agcaggccag taaggtgatc tgggaagact
    31261 attttccctt gctccgctat caaatcttgt caaatcccga cctaaccacc atctatcagg
    31321 tcaatcaaga aatggctgtg cgcattaaag aagctattaa aacagcccag tctgtggaag
    31381 aattggtcga gttagtgacc accaaacgtt acaccaaggc gcgtgtcaga cgcctcttga
    31441 cctatatctt ggtgcaggct agagaaagtg acttgccaga agggattcat gtccttggct
    31501 ttaccgaaaa aggcaggcaa catcttaaat atctgaaagg gcaggtcagt ctagtcagca
    31561 gaattggcaa ggaaccttgg gatgtcatga ctcaaaaggc agaccagatt taccaattgg
    31621 gaaatccaag tatagcagaa cagaattttg gcagagtgcc gattagaata gaaacaaact
    31681 aagtctactg aaaggtaggc ttttttattg tagaaatttt agctaacaaa ttgaagataa
    31741 agtttttgga aaatgataaa ctccctaata cagaagacaa aaagtcaata aagaaaatta
    31801 gtatatgaac cttaatcttt atctttgaat ccgctttatg cttgttattt tgtggtataa
    31861 tgaagagaac tggttatatt aaaaatcata aattgaatat aaaagacaaa taaattttta
    31921 tatttataaa ccatgataaa cttttgttta agattatgta ataaaaaaga aga
//
LOCUS       DAVKAU010000018        31807 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVKAU010000018 DAVKAU010000000
VERSION     DAVKAU010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31807
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.018"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(525..617)
                     /locus_tag="VWX48_001026"
     CDS             complement(525..617)
                     /locus_tag="VWX48_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU9171666.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            778..1749
                     /gene="ruvB"
                     /locus_tag="VWX48_001027"
     CDS             778..1749
                     /gene="ruvB"
                     /locus_tag="VWX48_001027"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU9171667.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1730..2302
                     /locus_tag="VWX48_001028"
                     /pseudo
     CDS             1730..2302
                     /locus_tag="VWX48_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            2533..3291
                     /locus_tag="VWX48_001029"
     CDS             2533..3291
                     /locus_tag="VWX48_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU9171668.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3300..4103
                     /locus_tag="VWX48_001030"
     CDS             3300..4103
                     /locus_tag="VWX48_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU9171669.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFVLTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4125..5384
                     /gene="rseP"
                     /locus_tag="VWX48_001031"
     CDS             4125..5384
                     /gene="rseP"
                     /locus_tag="VWX48_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU9171670.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5397..7250
                     /locus_tag="VWX48_001032"
     CDS             5397..7250
                     /locus_tag="VWX48_001032"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU9171671.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7349..8728
                     /gene="bglA"
                     /locus_tag="VWX48_001033"
     CDS             7349..8728
                     /gene="bglA"
                     /locus_tag="VWX48_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9171672.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGICLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDT
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            8920..10728
                     /gene="glmS"
                     /locus_tag="VWX48_001034"
     CDS             8920..10728
                     /gene="glmS"
                     /locus_tag="VWX48_001034"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU9171673.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGTDNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVVDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            10847..11896
                     /locus_tag="VWX48_001035"
     CDS             10847..11896
                     /locus_tag="VWX48_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU9171674.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(11996..15793)
                     /gene="spuA"
                     /locus_tag="VWX48_001036"
     CDS             complement(11996..15793)
                     /gene="spuA"
                     /locus_tag="VWX48_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU9171675.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATSKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSNDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRKESVENSSKENISATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            16210..16623
                     /gene="rpsL"
                     /locus_tag="VWX48_001037"
     CDS             16210..16623
                     /gene="rpsL"
                     /locus_tag="VWX48_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU9171676.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16643..17113
                     /gene="rpsG"
                     /locus_tag="VWX48_001038"
     CDS             16643..17113
                     /gene="rpsG"
                     /locus_tag="VWX48_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU9171677.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17538..19619
                     /gene="fusA"
                     /locus_tag="VWX48_001039"
     CDS             17538..19619
                     /gene="fusA"
                     /locus_tag="VWX48_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU9171678.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19723..24114
                     /locus_tag="VWX48_001040"
     CDS             19723..24114
                     /locus_tag="VWX48_001040"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU9171679.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQTTEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24216..24479
                     /locus_tag="VWX48_001041"
     CDS             24216..24479
                     /locus_tag="VWX48_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU9171680.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24472..24750
                     /locus_tag="VWX48_001042"
     CDS             24472..24750
                     /locus_tag="VWX48_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU9171681.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVCECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24771..24923
                     /locus_tag="VWX48_001043"
     CDS             24771..24923
                     /locus_tag="VWX48_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171682.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            24945..26186
                     /locus_tag="VWX48_001044"
     CDS             24945..26186
                     /locus_tag="VWX48_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU9171683.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NATSDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVLLFRNGNWAN"
     gene            26196..26426
                     /locus_tag="VWX48_001045"
     CDS             26196..26426
                     /locus_tag="VWX48_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9171684.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            26649..27371
                     /locus_tag="VWX48_001046"
     CDS             26649..27371
                     /locus_tag="VWX48_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9171685.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            27589..28923
                     /gene="pepC"
                     /locus_tag="VWX48_001047"
     CDS             27589..28923
                     /gene="pepC"
                     /locus_tag="VWX48_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU9171686.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAETIVLTPWDPMGALAE"
     gene            complement(28979..29890)
                     /locus_tag="VWX48_001048"
     CDS             complement(28979..29890)
                     /locus_tag="VWX48_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9171687.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(29914..30717)
                     /locus_tag="VWX48_001049"
     CDS             complement(29914..30717)
                     /locus_tag="VWX48_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU9171688.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(30745..31734)
                     /gene="manX"
                     /locus_tag="VWX48_001050"
     CDS             complement(30745..31734)
                     /gene="manX"
                     /locus_tag="VWX48_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU9171689.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVVANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIDISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT         9042 a         6139 c         7442 g         9184 t
ORIGIN      
        1 tttttcataa taatctccct taactccacc caatcaggtg gagtttttta gctctatttc
       61 aggcttttgg ggactattct aaaaataatt tttcgatatt tttcggtatt tttcggattt
      121 tggtcgggga attggcgggg acttttttag cgaatataac taagaaatag gtctgtggtc
      181 gcttcagcta gttcaaactc aatttgattg taagtgactg ttaattgaag aactggaact
      241 actgtaataa tgattttgct tgtctagtag tggcgtatta aatgagaagt gacatgtaag
      301 attgtctctt cgtttacgaa atcaaaattt ctatgaaatt gatagaatcc ctaacgttct
      361 cttaatctta accgtcttgt cgtacagcgg ttgaagaaaa tgtaaacctt tgacaaaatt
      421 cgtgaactat gggataataa aaaggaattg agtactagtt ctatatcata ggctagaaaa
      481 gaccccaagc tcacgaccaa ataagcttga ggtctttttt gacactattt gtccttgttt
      541 agccatttat cgactatacg aagaacgaca ccgaccacaa ttggtccgat gatagttttg
      601 agtactaatt ccatcatggg ctatctcacc tcctttcgta ggcggtgtag cagtgtcgta
      661 gaatattata ccacataagt gctaaactta ggagtcaccc aatcaggtgg cttttttgtt
      721 tgtggcttgg ttttttgata taatagagcc atgagtagaa ttttagataa tgagataatg
      781 ggggatgagg agttagtaga acgcacgctc cgtcctcagt atttacgtga atatatcgga
      841 caggataagg tcaaggacca gctacaaatc tttattgaag ctgccaaaat gcgggatgaa
      901 gcgctggatc atgtgctctt atttgggcct ccaggtctcg ggaaaacgac catggccttt
      961 gttattgcca acgaactggg agtcaatctt aagcagacgt cgggtccagt cattgaaaaa
     1021 gccggagatc tggtagctat tttgaatgag ttagagcctg gggatgtact ttttattgat
     1081 gagatccatc gtttgccaat gtcagtggaa gaggtgcttt atagtgctat ggaggacttc
     1141 tacatagata ttatgattgg ggctggtgag ggtagtcgta gtgttcattt ggagttacca
     1201 ccttttacct tgattggtgc gacgactcgg gctggtatgc tctccaatcc gctacgggca
     1261 cgttttggga ttacaggcca tatggagtat tatgcccatg ctgacttgac agaaattgtc
     1321 gagcggacgg cagatatttt tgagatggaa atcactcatg aggcagcatc tgagttggcc
     1381 ctacgtagtc gtgggacccc tcgtattgcc aatcgtctcc tcaagcgcgt gcgcgatttt
     1441 gcccagataa tggggaatgg ggtaattgat gatattatta ccgataaggc tttgactatg
     1501 ctggatgttg accatgaagg tttggactat gtggatcaaa aaatccttcg taccatgatt
     1561 gagatgtaca gtggaggacc tgttggtcta ggaactcttt ctgtgaatat cgccgaagag
     1621 cgtgagacag ttgaagatat gtatgagcct tacttgattc aaaaaggttt tatcatgcgg
     1681 acacggtctg gacgggtggc gactgctaag gcatatgagc acttaggtta tgaatacagt
     1741 gaaaaataag caagaaatct tagaggcttt tagagaaaat ccagatatga tggccattct
     1801 gacgatcatc cgagaccttg gtctgaaaga ctcgtggttg gcagcaggtt ctgtcagaaa
     1861 tttcatttgg aatcttttgt cagacaaatc cccttttgat catgaaacag atatagatgt
     1921 gattttcttt gatccagatt tttcttatga ggaaacctta ttactggaga aaaagctgtg
     1981 agaggatttt cctcagtacc agtgggaatt gaaaaatcag gtctatatgc atcagcacag
     2041 tcctcacact gcttcctata ccagttctcg tgatgctatg agtaagtatc cagaacggtg
     2101 tacgacagtt ggactgcgct tgaatgaaga atcagatttt gaactctatg caccttatgg
     2161 tttggaggat attttgaatt ttcaagttcg tccaactcct catttcttag aaaatgaaga
     2221 ccgaatggaa ctctatcaaa cacgtttatc caagaaaaat tggcaggaga aatggaaaaa
     2281 tttgattttt aaaaatactt aaggaaactt taagctaggg agtgtacact aagttcataa
     2341 gttaagaaga ccttaactta aactcctaaa actttttcat aataatctcc ctataaaaat
     2401 aaagtcgccc aatcaggcgg cttatttttt tgaaaaatgg gcttggtgcc tgagaataaa
     2461 tagcttagtg atagaagaaa atggggaaat atggtataat gaaacgatag atttttgaat
     2521 aggaataaga tcatgtttgg attttttaag aaagataagg ctgtggaagt agaggttccg
     2581 acacaggttc ctgctcatat cggcatcatc atggatggca atggccgttg ggctaaaaaa
     2641 cgtatgcaac cgcgagtttt tggacataag gcgggcatgg aagcattgca aaccgtgacc
     2701 aaggcagcca acaaactggg cgtcaaggtt attacggtct atgctttttc tacggaaaac
     2761 tggacccgtc cagatcagga agtcaagttt atcatgaact tgccagtaga gttttatgat
     2821 aattatgtcc cggaactaca tgcgaataat gttaagattc aaatgattgg ggagacagac
     2881 cgcctgccta agcaaacctt cgaagcttta accaaggctg aggaattgac taagaacaac
     2941 acaggattga ttcttaattt tgctcttaac tatggtggac gtgctgagat tacacaggcg
     3001 cttaagttga tttcccagga tgttttagat gccaaaatca acccaggtga catcacagag
     3061 gaattgattg gtaactatct ctttacccag catttgccta aggacttacg agacccagac
     3121 ttgattatcc gtactagtgg agaattgcgt ttgagcaatt tccttccatg gcagggagcc
     3181 tatagtgagc tttattttac ggacacctta tggcctgatt ttgacgaagc ggccttgcag
     3241 gaagctattc ttgcctataa tcgtcgccat cgccgatttg gaggagttta ggaggaaata
     3301 tgacccagga tttacagaaa agaaccttgt ttgcagggat tgccctggct attttcctac
     3361 caattttaat gattgggggc ctcttgcttc agatagcaat cggaatcata gccatgctag
     3421 ccatgcatga acttttgaag atgagaggtc tagagaccat gacgatggag ggcctcttga
     3481 ccctctttgc aacctttgta ttgaccattc ccctggaaaa ttacctgact tttttgccag
     3541 ttgatgggaa tgtggttgcc tatagtgttt tgatttcaat catgttagga acgaccgttt
     3601 ttagcaagtc ttatacgatt gaggatgcgg ttttccctct tgctatgagc ttctacgtgg
     3661 gctttggatt taatgcttta ctagatgctc gtgttgcagg tttggacaag gctctcttag
     3721 ccttgtgtat cgtctgggcg acagacagtg gtgcctatct tgttgggatg aactatggga
     3781 aacgaaagtt agcaccaagg gtatcgccta ataaaaccct tgagggtgcc ttgggtggta
     3841 ttttaggagc aattttagta accattatct ttatgatagt tgacagtaca gttgctcttc
     3901 catatggaat ttacaagatg tcagtctttg ctattttctt tagcattgct ggacaatttg
     3961 gtgatttact agaaagttcg atcaaacgtc attttggtgt taaggattct gggaaattta
     4021 tccctggaca tggtggtgtt ttggatcgtt tcgatagtat gttgcttgta tttccaatca
     4081 tgcacttatt tggactcttt taatcaaaag acggaggaaa cgctatgctc ggaattttaa
     4141 cctttattct ggtttttggg attattgtag tggtgcacga gttcgggcac ttctactttg
     4201 ccaagaaatc agggatttta gtacgtgaat ttgccatcgg tatgggacct aaaatctttg
     4261 ctcacattgg caaggatgga acggcctata ccattcgaat cttgcctctg ggtggctatg
     4321 tccgcatggc cggttggggt gatgatacaa ctgaaatcaa gacaggaacg cctgttagtt
     4381 tgacacttgc tgatgatggt aaggttaaac gcatcaatct ctcaggtaaa aaattggatc
     4441 aaacagccct ccctatgcag gtgacccagt ttgattttga agacaagctc tttatcaaag
     4501 gattggttct ggaagaagaa aaaacatttg cagtggatca cgatgcaacg gttgtggaag
     4561 cagatggtac tgaggttcgg attgcacctt tagatgttca atatcaaaat gcgactatct
     4621 ggggcaaact gattaccaat tttgcaggtc ctatgaacaa ttttatctta ggtgttgttg
     4681 ttttttgggt tttaatcttt atgcagggtg gtgtcagaga tgttgatacc aatcagttcc
     4741 atatcatgcc ccaaggtgcc ttggccaagg taggagtacc agaaacggca caaattacca
     4801 agattggctc acatgaggtt agcaactggg aaagcttgat ccaagctgtg gaaacagaaa
     4861 ccaaagataa gacggcaccg actttggatg tgactatttc tgaaaagggg agtgacaaac
     4921 aagtcactgt tacacccgaa gatagtcaag gtcgttacct tctaggtgtt caaccggggg
     4981 ttaagtcaga ttttctatcc atgtttgtag gtggttttac aactgctgct gactcagctc
     5041 tccgaattct ctcagctctg aaaaatctga ttttccaacc ggatttgaac aagttgggtg
     5101 gacctgttgc tatctttaag gcaagtagtg atgctgctaa aaatggaatt gagaatatct
     5161 tgtacttctt ggcaatgatt tccatcaata ttgggatttt taatcttatt ccgattccag
     5221 ccttggatgg tggtaagatt gtgctcaata tcctagaagc catccgccgc aaaccattga
     5281 aacaagaaat tgaaacctat gtcaccttgg ccggagtggt catcatggtt gtcttgatga
     5341 ttgctgtgac ttggaatgac attatgcgac tcttttttag ataatcgagg aatattatga
     5401 aacaaagtaa aatgcctatc ccaacgcttc gcgaaatgcc aagcgatgct caagttatca
     5461 gccatgctct tatgttgcgt gctggttatg ttcgccaagt ttcagcaggt gtttattctt
     5521 atctaccact tgccaaccgt gtgattgaaa aagctaaaaa catcatgcgc caagaattcg
     5581 aaaagattgg tgctgttgag atgttggctc cagcccttct tagtgcagaa ttgtggcgtg
     5641 aatcaggtcg ttacgaaacc tatggtgaag acctttacaa actgaaaaac cgtgaaaaat
     5701 cagactttat cttaggtcca actcacgaag aaacctttac agctattgtc cgtgattctg
     5761 ttaaatctta caagcaattg ccactcaacc tttatcaaat tcagcccaag tatcgtgatg
     5821 aaaaacgccc acgtaatgga cttcttcgta cacgtgagtt tatcatgaag gatgcttata
     5881 gtttccacgc taactatgat agtttggata gtgtttatga tgagtacaaa gcagcctatg
     5941 agcgtatttt cactcgtagt ggtttagact tcaaggctat tattggtgac ggtggagcca
     6001 tgggtggtaa ggatagccaa gaatttatgg ccattacatc tgctcgtaca gaccttgacc
     6061 gctgggttgt cttggacaag tcagttgcct catttgacga aattcctgca gaagtgcaag
     6121 aagaaatcaa ggcagaattg ctcaaatgga tagtctctgg tgaagatacc attgcttact
     6181 caagtgagtc tagctatgca gctaacttag aaatggcaac aaacgagtac aaaccaagca
     6241 accgtgttgt cgctgaagaa gaagttactc gtgttgcaac gccagatgtt aaatcaattg
     6301 atgaagttgc agccttcctc aatgttccag aagaacaaac gattaaaacc ctcttctaca
     6361 ttgcagatgg tgagcttgtt gcagcccttc tagttggaaa tgaccaactc aacgaagtca
     6421 agttgaaaaa ccacttagga gcagatttct ttgacgttgc tagcgaagaa gaagtggcga
     6481 atgttgttca agcaggattt ggttcacttg gaccagttgg tttgccagag aatattaaaa
     6541 ttattgcaga tcgtaaggtg caagatgttc gcaatgcagt tgtcggtgct aacgaagatg
     6601 gctaccactt gactggtgtg aacccaggcc gtgattttac tgcagaatat gtggatatcc
     6661 gtgaagttcg tgagggtgaa atttccccag atggacaagg tgtccttaac tttgcgcgtg
     6721 gtattgagat cggtcatatt ttcaaactcg gaactcgcta ctcagcaagc atgggagcag
     6781 atgtcttgga tgaaaatggt cgtgctgtgc caatcatcat gggatgttac ggtatcggtg
     6841 tcagccgtct tctttcagca gtgatggagc aacacgctcg cctctttgtt aacaaaacgc
     6901 caaaaggtga ataccgttac gcttggggaa tcaatttccc taaagaattg gcaccatttg
     6961 atgtgcattt gattactgtc aatgtcaagg atgaagaagc gcaagccttg acagaaaaac
     7021 ttgaagcaag cttgatggga gctggttatg aagtcttgac agatgaccgt aacgaacgtg
     7081 tcggtgttaa atttagcgat agtgacttga ttggtcttcc aatccgtatc actgttggta
     7141 aaaaagcggc cgatggcatt gtagaagtta agatcaaggc aactggtgac accattgagg
     7201 ttcatgcaga taacgtgctt gaaacgcttg aaatcctaag caagaaataa aaactataat
     7261 cagaagaaaa acaaggaaaa aatgtaacta gtttttacct tgttttttct gtataatggg
     7321 agaaatgagt agataaagag gtaaatgtat gctaagattt ccaaaggatt ttgtctgggg
     7381 atcctctact tctggaccgc agacagaagg acgtgtagct ggtgacggta agggagacaa
     7441 tctctgggat tactggttcc aagtggagcc aaatcgttac tataatggga ttggttcaga
     7501 taagacatcg actttttatg aaaattggga gcgggatatt gagcttttgt tagagactgg
     7561 tcacacagcc tttcggactt ctattcagtg gtcacggatt tttccacaag gctgtggaaa
     7621 agtcaacact caaggtgtgg atttttatcg taaggtcttt gaggctatta aggctaaagg
     7681 aatttgtctg ttagtcaatc tctatcattt tgatttacct tttgcccttc aagaggatgg
     7741 tgatggttgg gaaaataagg cgacagtctc agcctatgaa gactatgctc gtttttgttt
     7801 tgagacttat ggagatttag tggatcaatg gattaccttt aacgagccca tcgttcctgt
     7861 agaatttggt tatttttatg atgcccatta tccacataag gtggatgcag aggcagctgt
     7921 taaggtagcc tatcatacac aattggccag cagccgggct gttaaggctt gccatgaact
     7981 tttgcctgat tccaagattg ggattgtcct caacttgaca ccggcttatc cacgtagcca
     8041 gcatcctgct gatgtcaagg cagctcgtat tgcggccctt tttcaggccc aatctttctt
     8101 agatccatct gtcttgggga cttatccaca ggagttggta gaaatcttgc atgaacacgg
     8161 tcttttacct gatactacag aggaagagtt ggaactcatt cgtgataata cggtggactt
     8221 ccttggtgtg aactactatc aacctttgcg tgttatggct cctcgatttg ctaagcatcc
     8281 agatagtcca ctcttaccag aacattttta cgagccttat gtgatgcctg gacgtaaaat
     8341 caattctcac cgtggttggg agatttatga gcaagggatt tatgacatcg cccaaaatat
     8401 caaggaaaat tatggcaata ttgagtggat gttgactgag aatggtatgg gtgttgaagg
     8461 ggaagaaaaa ttccgtcaag atggaatgat tcaagatgat taccgtattg actttgtaaa
     8521 aggtcatctt cgtgaacttc accgtgccat tgaagatggt gccaactgta agggctactt
     8581 gatttggacc tttattgact gctggtcatg gctcaacagc tataaaaatc gctatggttt
     8641 ggtcgaatta gacttggaaa cgcaagaacg tcgtctgaag aaatcaggcc actggttcaa
     8701 agaattaagc gataataatg gattttaaaa aggactctga ctgattatcc caatcggtca
     8761 gagttttttg cttacaggag cttaatttga actataccaa tttttactct tgacaagtga
     8821 aagaaacaag tatatactgt ttttgctgat tctataaaag atgaattaga ctataccaat
     8881 tttaaggaga aagcacagct tgcctgtgtc gtatatacta tgtgtggaat tgttggtgtt
     8941 gttggaaaca caaatgcaac tgatattttg attcaagggc ttgaaaagct tgaataccgt
     9001 ggctatgatt ctgcgggaat ttttgtccta gatggtactg ataaccattt ggtgaaggct
     9061 gttggtcgta tcgcagaatt gtctgctaag acagctggtg ttgagggaac aactggtatc
     9121 ggacatactc gttgggcaac tcatgggaaa ccaacggaag acaatgctca cccacaccgc
     9181 tctgagacag aacgttttgt cttggttcac aatggggtga ttgaaaacta ccttgaaatt
     9241 aaagaagaat accttgctgg gcaccacttc aaagggcaaa cagatacgga aatcgccgta
     9301 catttgattg gaaaatttgc ggaagaagac ggtctctcag ttcttgaagc ctttaaaaaa
     9361 gctcttcata ttatccgtgg ttcatatgcc tttgccttga ttgactctga aaatccagat
     9421 gtcatctatg tagcgaaaaa caaatctcca cttttgattg gtcttgggga aggctacaat
     9481 atggtctgct cagatgctat ggctatgatt cgtgaaacca accaatacat ggaaattcat
     9541 gaccaagagt tggtaatcgt caaggctgat agcgtggaag ttcaagacta tgatggtaac
     9601 agtcgtgaac gtgctagcta tactgcggaa cttgacttgt cagatatcgg taagggaact
     9661 tatccttact acatgcttaa ggaaattgat gagcaaccaa ctgttatgcg taaactcatt
     9721 caagcctaca cggatgatgc tggtcaagta gtggttgatc ctgctatcat taaggctgtt
     9781 caagacgcag accgcatcta catccttgca gctggaacat cttaccatgc aggatttgct
     9841 tctaagaaaa tgttggaaga attgacagat acaccagttg aacttggcat ctcatctgag
     9901 tggggctacg gtatgccact tctcagcaag aaaccactct tcatctttat cagccaatct
     9961 ggtgaaacag cggatagtcg tcaagttttg gtcaaggcta atgaaatggg aattccaagc
    10021 ttaacagtga caaatgttcc aggctcaacc ctctcacgtg aagccaacta taccatgctc
    10081 cttcacgcag gtcctgaaat tgccgtggca tcaactaaag cctatacagc gcaaatcgca
    10141 gcccttgcct tccttgcaaa agcagtcgga gaagcaaatg gtaatgctaa agcgcaagcc
    10201 tttgacctga ttcatgaatt gtcaatcgta gctcagtcta tcgaatcaac tctttcagag
    10261 aaagaaacca ttgaagccaa ggttcgtgaa cttcttgaaa caactcgtaa cgccttttac
    10321 atcggacgtg gtcaagatta ctacgtagcc atggaagcaa gtctcaaact caaagagatt
    10381 tcttatatcc agtgtgaagg ctttgctgca ggagaactca agcacggaac cattgccttg
    10441 attgaagaag gaacgcctgt tttggctctc ttgtcagatc cagttcttgc caatcatact
    10501 cgtggaaata tccaagaggt cgcagcccgt ggtgccaaag tcctcactat cgcagaagag
    10561 aatgtagcca aagataccga cgatatcgtc cttacgaccg tacatccata cctctcacca
    10621 atttcaatgg tcgtaccaac gcaattagtc gcttactttg caaccctcca ccgtggcctc
    10681 gatgtggaca aaccacgtaa ccttgccaag tcagtaacgg tagaataagc taaaaaagtc
    10741 tagttatcta ggctttttct tgtgagcaaa ttggttgctt gtactcaaga ttcgtgttag
    10801 aataattttt caaattgaag gacagagata gacaaggaga atcacaatgg tagaattggg
    10861 aatttcaaca tttggggaaa taacggagct tgaagggact ggacaaactt acagtcatgc
    10921 tgaacgcatt cgccagttgg tggcagagat tgagctggct gacaaggttg gtttggacgt
    10981 atatgggatt ggcgagcacc atcgggcgga ttttgcagta tcagccccag agattgtcct
    11041 ggccgctggg gcagtcaata ccaagaaaat ccgtttgacc agtgcagtca gcattctgtc
    11101 aagcatggac ccgattcgtt tgttccaaca gtatgccact atcgatgctt tgtcaaatgg
    11161 acgatcggag attatggctg gaaggggctc tttcacggaa tctttccctc tgtttggtta
    11221 tgacttgaaa gactacgact ctctttttga tgagaaatta gacttgcttc agttagtcaa
    11281 tgaaaagacc aagttagact ggcaaggtcg attgactcaa acgattgctg gtaaagaagt
    11341 ttatcctcgt ccagttcagg acaaattgcc cttgtggata gctacaggtg gtcatgtcga
    11401 atcaacagtg aagattgctc aggctggtct accgattgta tatgctatta ttggtggtaa
    11461 tccacgttat tttaaaaagt tgattcaggc ttatcgtgag attggaagcg aagcgggcca
    11521 tgctgacaaa gacttgaaag tgggagccca ttcttggggg tggattgcgg aagatggtga
    11581 gcaggcggtg aaagattatt tccatccgac taagcaagtg gtggatgcta tttccaaaga
    11641 ccgtccgcac tggcaggaat tgcgttatga gcaatatttg gagcaggtag ggtcaaatgg
    11701 cgccatgttt gttggcaatc cagatcaggt ggccgaaaaa ttgattcgca tgatagagga
    11761 tttaggattg gaccgcttca tgcttcatct accgcttggt tctatgcctc atgaccaggt
    11821 tctgagagct attgaactct tcggaacaca agttgcaccc aaagtacgag cttattttgc
    11881 tatgaaagag gcttaataaa aaatcctaat caagtttatt aggacaacaa atattgtacg
    11941 aaaattaatc ccccgagcta taatgcttgg gggatttttc tataggaggg ctagcttagt
    12001 tctctttttt attttttagt aagaaaccga gaccaaggag cgcaaggagg ctgattcctg
    12061 caaataggag tttgttttcg tttttgattc ctgtatttgg aagttcagct tgtctatctg
    12121 gggttgcaga tatattttcc ttgctagagt tttctaccga ttcttttcga accgcttctt
    12181 ttacagatga tgcttgtgct tcttgtgctg gttgttcagc ttgtgaatca gctgtagctt
    12241 ggctaggttt attttccgca tcagctactt tggcatctgg tttagtagaa tcaggtctag
    12301 cttctggagc tgggtcttga tgtgcagggt gagaagcttc attttgatgt tcaggcttgg
    12361 aaggggttga gtctggtttc tcttctgcag ttgactcatg gctagttcca ttttgagaga
    12421 ctcgaagaac agtagctgta agggcattca attttaagcc tttttcagtc cattcaagtc
    12481 ctttcgggtt ggcaattccg actgatcctg cttggttttc atctgccaaa acttccgcat
    12541 ttcttagatg tgcaaaggca gttcccaaat taaattcgcg agctttttca tccgcattga
    12601 caaagactgc gtagatatcg ccgtttggag cagtgatttg gtagccaatc actacatcct
    12661 ctttttccac accattttgg cctgggacag tgatgaggtg gacacggtct ttgatatctt
    12721 ggagactctt aagtcggaag gcatctgtag attgacgaag ggcaatcaaa cctttcatat
    12781 agtcacggct cttgacattt tcaggataag ctttaccatc tgtagcctta gtccagtcaa
    12841 acttgttgac tgcgtcgcta gaatcgtaag aatcatggat gaagtaagga tagtcaaatg
    12901 ggttgccgtc cttatcacgc aacaagtgag atttgtttgg aaccttatcc tctgctactg
    12961 gagtcttgta ggctgggtca cggaattgtt tagtacgtcc atattcctga ccggagtgga
    13021 taaatggagt tccttgagct gtcaagacca tgagatttcc aagtcgtaaa cgacggtgga
    13081 tttcagcata gttctcagcc ttgcttgggt cttttttgat agactgggca atgatgtcaa
    13141 agagggtcaa gttatcatgg gctgcgatgt attggatgac atctccaggg ctgtcagctt
    13201 caaagttagt tggttgagca atgagatttt taaagatggt gttgacatca cgcttgccac
    13261 ctgtgataaa ggcaggttga ccttcgtttg gataaccaga tttgaggttg ttacggatgt
    13321 catctgaaaa gacagcgaca gtatcggtat gtttcatcca atcttggtca gcagctttag
    13381 taggcatgtt ttcatcaccg gcataggttc tccaaccttc gcctaacatg attagatttg
    13441 gattgagggc gcgtgcagcc ttgtaagctt cttcgataga agcggcgtca tggtctccca
    13501 tcatatcgaa gcggaagcca tccactttgt aggtatcaac taggtatttg atagagtcaa
    13561 ctaggaggcg tttggtcata tggtgggttg tccccaagcg tccaccacca aagctagttc
    13621 gaggtgtgcc atcggcatcc ataaagtggt agtagtttgg ctctaggtct tcaaagatat
    13681 cgactttggc tgtgtggtta taaacgacat ctaggatagc tcccatacca cgtttgtgga
    13741 tttcgttgat gaggttttta aattctgcga ttcgtttttc tggattctta ggatcgcttg
    13801 agtacatacc agtcaaggag aagtagtttt gagggtcata tccccagttg tagttgctgt
    13861 tgcttgaagc atagtcagac aagcgttcat ggtttttcaa ttcattgaca aagtagtaag
    13921 acaagactgg aaggagctgg atatgggtta cacccaagtc tttgagatag tctagttttt
    13981 caatgaaggc ttcaaaagtc ccaaatggtt tggtcaagtc ttttgcaatg gcaggatctg
    14041 aagtgaagtc acgcacatga gcttcgtaga taacggcgtc ttcacgagtc ttgaaattgt
    14101 gaatcttacc ataagtcaag tcttgaggtc cgagtttagc tggatctaca aaggcggctt
    14161 tagccacttt atgggcatcg tcaatcttgg catcgttgct attccaagca gcaagagatt
    14221 tagcgtaagg atcgagtgca agaacagttt taccttgacg ctcgatttgg tattgataat
    14281 agtagccagt gaaatctgtg attccgagtt tgtttgtgct gtctagagtt tgtttccaag
    14341 ttcctctttc ccctttttcg agagcgacag ttccaactac tttgtcaggg tcattcttgt
    14401 cgtagacaac aacagaaacc ttatcagcac ttggtgacca aagggtcaaa tcaacttgtt
    14461 ttccttcttc ttttaggtca gctcctagtt tgccatcata gctgtatgtc tcatctttca
    14521 ggcgccagct tgttttggta gtgaattggt cggaattgta gctaacagta taaggatgtt
    14581 ttgtgtcaga gaaatctccg ctgtaggtca ctttcttacc agcttcatcg attgcaacat
    14641 cggtaatagt taccttgttt cctaggtgat tagtgatgtt ggagtgtttg aggatatctt
    14701 cttttttagc accgacaagt gttgaaaagc tactttcaat gctagaagtg cctacgtgtt
    14761 gggctcctgt catacggata tcatggacat agtatggatt tgtgtaaatc gattcatcat
    14821 cgtcttttag gaaaatttgg ctatgatttt tcaaatctgt gaacttataa ttttctttac
    14881 ggattttcac gtcgtctcct tgtttgctct catctagtaa taaaaatcca aattctcttg
    14941 cggcttcatt aagaggaatg tcgatatagc ggccatattt gcttgtagcc gtaaagtctg
    15001 ttccgtcagg ccattgagcg ctacttggat tttttacatc tccccagtac cagagagatt
    15061 tcttgtcata gttgccatct gtgcggtagt agttgacgcg aacagttcct gcaggctgtg
    15121 gctcgtaaga gaaaaccttg taatcttggt ctaaccaagc ctcgttcatt tttggaacta
    15181 gtttttctac agatttatcg ccggttagat tttttccagc tgtattgttg atgaggaagc
    15241 taattttctt ggcttgttct ccctttaatt tgacatctag gtaatagccg tagtcatctt
    15301 tcttggcatc cttgaaggac aaagctccgt ttggccagtt ttcagatggt ttttcaacat
    15361 cgtcccaagt ccatagtcct tgagcatcct tgttttcttc aggaagtttt ttgacatgga
    15421 tacggaagta gttatcttcg atgggctctt ctgccttagt ttcagttgtt actggactag
    15481 tagaagtagt tggctctgtt gcaggttttt cttctgtttt ctctagggaa gcgtttgcat
    15541 ttctaggtga agaaatatca ctttcgttct taccagagcc agctgctgta tcagtaagag
    15601 gttgggcaag ggtggttgta tttctgttgt tgggttcgtt agtggttggt gtactttcgt
    15661 cggatgagat agttggtgta gccatggcaa gcaagacaag gcttgcgccg ataaggacag
    15721 aaccagtccc atttttgagg gaacggatgc tgtagaccat ttttttctca gtgtgagatg
    15781 gtgtttttct cataatgatt ctccaatcaa taaatttcta tatcagtata gcatgtagta
    15841 aaacaatatg caagcgtttt ctttgatttg tgaaaaaaat tcttactttt gagaagtttt
    15901 ctgtactatt ttatatatca gtataaatga cggagataaa aatgtcacat aagccaagcc
    15961 gtattattag gaagatgatg tgttcccagc tatttttatt cagaaattga tctctaacat
    16021 taccaataaa aaagaaaaat atcttgacaa acaagggaaa attttgttac aataatagac
    16081 ggtacttttt acttttggtc tctcaagagt gtacagggac gtgctgacaa atgttgcaaa
    16141 agtacacaca gatgatatct gtcaccaagt gtatcatcac caaaaataaa aaaacacagg
    16201 agaatgtaga tgcctacaat taaccaattg gttcgcaaac cgcgtaaatc aaaagtagaa
    16261 aaatctaaat caccagcttt gaacgttggt tacaatagtc ataaaaaagt tcaaacaaac
    16321 gtttcttcac cacaaaaacg tggtgttgca actcgtgttg gaacaatgac acctaaaaaa
    16381 cctaactcag cccttcgtaa attcgctcgt gtacgtttga gcaaccttat cgaagttact
    16441 gcctacatcc caggtatcgg acacaacttg caagagcaca gcgtggtgct tcttcgcggt
    16501 ggacgtgtaa aagaccttcc aggggtacgt taccatatcg tccgtggtgc acttgatact
    16561 gcaggtgtta acgatcgtaa acaaggtcgt tctaaatacg gtactaaacg tccaaaagca
    16621 taaggaaagg ggataaagag aaatgagtcg taaaaataga gctccaaaac gtgacgtatt
    16681 gccagatccg ctatacaatt cacaactagt tactcgtctt atcaaccgcg ttatgcttga
    16741 tggtaaacgt ggtactgctg cttcaatcgt ttacggtgct tttgagcaaa tcaaagaagc
    16801 tactggcaac gatgcacttg aagtatttga aacagctatg gaaaacatca tgcctgtact
    16861 tgaagtacgt gcacgtcgtg ttggtggttc taactaccaa gtcccagttg aagttcgtcc
    16921 agaacgtcgt acaacacttg gacttcgttg gttggtaaca atcgctcgtc ttcgtggtga
    16981 acacacaatg caagaccgtc ttgcaaaaga aatcttggat gctgctaaca acactggtgc
    17041 agcagttaag aaacgtgaag atactcaccg tatggctgaa gctaaccgtg cattcgcaca
    17101 cttccgttgg taagatagga tgcgaaagcg ttaagaaagt tccagagaaa atagggaatc
    17161 gaagcaggtt gcggttgcaa ccaatgagat tcatcttttt ctccagactt ttagcttgag
    17221 ctcaactaaa tcatgatgtt aggaacggta aggatgcaag gtgaaaatag gaaactgacg
    17281 cagtattcga cgaatacaag gagttttatc tttttcacgc agcatcccgt tccagctcac
    17341 atcggctaac taactttagc ccgggttcaa attagctaaa tcgattagta ttagctataa
    17401 ctcagcttac catctcgtaa gttgaaacca acaatagcat gaaaacattg agaacgggta
    17461 ggtcctgcct atccgttttt attaaaatcg tgttataata gaatagaaat caaaaataaa
    17521 taggagaaac aaacctcatg gcacgcgaat tttcacttga aaaaactcgt aatatcggta
    17581 tcatggctca cgtcgatgcc ggtaaaacaa caactactga gcgtattctt tactacactg
    17641 gtaaaatcca caaaatcggt gaaactcacg aaggtgcgtc acaaatggac tggatggagc
    17701 aagagcaaga acgtggtatc acgatcacat ctgctgcgac aacagctcaa tggaacaacc
    17761 accgcgtaaa catcatcgac acaccaggac acgtggactt cacaatcgaa gtacaacgtt
    17821 ctcttcgtgt attggatggt gcggttaccg ttcttgactc acaatcaggt gttgagcctc
    17881 aaactgaaac agtttggcgt caagcaactg agtacggagt tccacgtatc gtatttgcca
    17941 acaaaatgga caaaatcggt gctgacttcc tttactctgt aagcacactt cacgatcgtc
    18001 ttcaagcaaa tgcacaccca atccaattgc caatcggttc tgaagatgac ttccgtggta
    18061 tcattgactt gatcaagatg aaagctgaaa tctatactaa cgaccttggt acggatatcc
    18121 ttgaagaaga catcccagct gaataccttg accaagctca agaataccgt gaaaaattga
    18181 ttgaagcagt tgctgaaact gacgaagaat tgatgatgaa atacctcgaa ggtgaagaaa
    18241 tcactaacga agaattgaaa gctggtatcc gtaaagcgac tatcaacgtt gaattcttcc
    18301 cagtattgtg tggttcagcc ttcaaaaaca aaggtgttca attgatgctt gatgcggtta
    18361 tcgactacct tccaagccca cttgacatcc cagcaatcaa aggtattaac ccagatacag
    18421 acgctgaaga aattcgtcca gcatctgacg aagagccatt tgcagctctt gccttcaaga
    18481 tcatgactga cccattcgta ggtcgtttga cattcttccg tgtttactca ggtgttcttc
    18541 aatcaggttc atacgtattg aatacttcta aaggtaaacg tgaacgtatc ggacgtatcc
    18601 ttcaaatgca cgctaacagc cgtcaagaaa tcgacactgt ttactcaggt gatatcgctg
    18661 ctgccgttgg tttgaaagat actacaactg gtgactcatt gacagatgaa aaagctaaaa
    18721 tcatccttga gtcaatcaac gttccagaac cagttatcca attgatggtt gagccaaaat
    18781 ctaaagctga ccaagacaag atgggtatcg cccttcaaaa attggctgaa gaagatccaa
    18841 cattccgcgt tgaaacaaac gttgaaactg gtgaaacagt tatctcaggt atgggtgaac
    18901 ttcaccttga cgtccttgtt gatcgtatgc gtcgtgagtt caaagttgaa gcgaacgtag
    18961 gtgctcctca agtatcttac cgtgaaacat tccgcgcttc tactcaagca cgtggattct
    19021 tcaaacgtca gtctggtggt aaaggtcaat tcggtgatgt atggattgaa tttactccaa
    19081 acgaagaagg taaaggattc gaattcgaaa acgcaatcgt cggtggtgtg gttcctcgtg
    19141 aatttatccc agcggttgaa aaaggtttgg tagaatctat ggctaacggt gttcttgcag
    19201 gttacccaat ggttgacgtt aaagctaagc tttatgatgg ttcatatcac gatgtcgact
    19261 catctgaaac tgccttcaag attgcggctt cactttccct taaagaagct gctaaatcag
    19321 cacaaccagc tatccttgaa ccaatgatgc ttgtaacaat cactgttcca gaagaaaacc
    19381 ttggtgatgt tatgggtcac gtaactgctc gtcgtggacg tgtagatggt atggaagcac
    19441 acggtaacag ccaaatcgtt cgtgcttacg ttccacttgc tgaaatgttc ggttacgcaa
    19501 cagttcttcg ttctgcatct caaggacgtg gtacattcat gatggtattt gaccactacg
    19561 aagatgtacc taagtcagta caagaagaaa ttattaagaa aaataaaggt gaagactaat
    19621 ccgtcctcac tctagaagga agtcacttag tggcttcctt ttgtctttag aaaatacctc
    19681 taaatatggt aaaatagtag aagaataatg tgaggaaaat gaatgtcaaa tagttttgaa
    19741 attttgatga atcaattggg gatgcctgct gaaatgagac aggctcctgc tttagcacag
    19801 gctaatattg agcgagttgt ggttcataaa attagtaagg tatgggagtt tcatttcgta
    19861 ttttctaata ttttaccgat tgaaatcttt ttagaattaa agaaaggttt gagcgaagaa
    19921 ttttctaaga caggcaataa agctgttttt gaaattaagg ctcggtctca agaattttca
    19981 aatcagctct tgcagtccta ctatagggag gctttctctg aaggtccatg tgctagtcaa
    20041 ggttttaagt ccctttatca aaatttgcaa gttcgtgctg agggcaatca gctatttatt
    20101 gaaggatctg aagcgattga taaggaacat tttaagaaga atcatcttcc taatttagcc
    20161 aaacaacttg aaaagtttgg ttttccaact tttaactgtc aagtagagaa gaatgatgtc
    20221 ctgacccaag agcaggaaga ggcctttcat gctgaaaatg agcagattgt tcaagctgcc
    20281 aatgaggaag cgctccgtgc tatggaacaa ctggagcaga tggcacctcc tccagcggaa
    20341 gagaaaccag tctttgattt tcaagcgaaa aaagctgcag ctaaacccaa gctggataag
    20401 gcggagatta ctcctatgat cgaagtgacg acagaggaaa atcgtctggt ctttgaaggg
    20461 gttgtttttg atgtggagca aaaagtgact agaacaggtc gtgttttaat caactttaaa
    20521 atgacggact acacttcaag tttttctatg caaaagtggg ttaaaaacga ggaagaggcc
    20581 cagaagtttg acctcatcaa gaagaattct tggctccgag ttcgagggaa tgtggagatg
    20641 aataacttca cacgcgattt gactatgaac gtacaggatg tgcaggaagt tgttcactat
    20701 gagcggaagg atttgatgcc agaaggtgag cgtcgggttg agtttcatgc tcatactaac
    20761 atgtcgacta tggatgcttt gccagaggtc gaagagattg ttgcaacagc tgctaagtgg
    20821 ggacacaagg cggttgctat tacggaccat gggaatgtcc agtcctttcc acatggctat
    20881 aaggcggcta agaaagcggg aatccagctg atctatggga tggaagccaa tatcgtggag
    20941 gaccgtgtcc ctatcgtcta taacgaagtg gagatggact tgtcagaagc aacctacgtg
    21001 gtctttgacg tggaaacgac gggactttca gctatctata atgacttgat tcaggttgcg
    21061 gcctctaaga tgtacaaggg gaatgttatt gctgaatttg atgaatttat caatcctggg
    21121 catcccttgt cagcctttac tacagagtta actggaatta cagatgatca tgtcaaaaat
    21181 gccaaaccac tagaacaagt tttgcaagaa ttccaagaat tttgcaagga tacggtccta
    21241 gttgcccaca atgctacctt tgacgttggc tttatgaatg ctaattatga gcgtcatggt
    21301 cttccaaaga ttagtcagcc agttattgat acgctggagt ttgctagaaa cctctatcct
    21361 gagtataaac gccatggttt ggggcctttg accaagcgtt ttggtgtggc cttggaacat
    21421 caccacatgg ccaactacga tgcggaagcg actggtcgtc tgcttttcat ctttatcaaa
    21481 gaggtagcag aaaaacatgg tgtgaccgat ttagctagac tcaacattga tctaatcagt
    21541 ccagattctt acaaaaaagc tcggatcaag catgcgacca tctatgtcaa gaatcaggta
    21601 ggtctaaaaa atatctttaa gctggtttcc ttgtctaata ccaagtattt tgaaggagtg
    21661 ccacggattc cgagaacggt tctagatgcc catcgagagg gcttgatttt aggttcagcc
    21721 tgttcagagg gtgaagtttt tgacgtggtc gtttctcaag gtgtggatgc ggcggttgag
    21781 gtggccaagt attatgactt tatcgaggtc atgccaccgg ctatctatgc gcccttgatt
    21841 gccaaagagc aggtcaagga tatggaggaa ctccagacca ttatcaagag tttgatagag
    21901 gttggagatc gccttggcaa gcctgttctg gctacgggaa atgttcacta tatcgaaccg
    21961 gaagaagaga tttatcgtga aattatcgtc cgtagtttgg gacagggtgc gatgattaac
    22021 cgaactatcg gtcatggtga acatgcccaa ccagcgccac ttccaaaggc tcattttcga
    22081 acgactaatg agatgttgga tgaatttgcc tttttgggag aggaactggc tcgtaaactg
    22141 gttattgaaa acactaatgc cttggcagaa atatttgaac ccgttgaagt cgttaagggt
    22201 gacttgtata cgcctttcat cgacaaggct gaagaaacag ttgctgagtt gacctataag
    22261 aaagcttttg agatttatgg aaatccgctg ccagatattg ttgatttgcg gattgaaaaa
    22321 gaattaacat ccatactggg gaatggattt gctgtgattt atctggcatc gcagatgctg
    22381 gtgcaacgtt ctaatgaacg gggttatttg gttggttctc gtgggtctgt cggatctagt
    22441 ttcgttgcga ccatgattgg gattacggag gtcaatcctc tctctcctca ctatgtctgt
    22501 ggtcagtgtc agtacagtga gtttatcaca gatggttcgt acggttcagg atttgatatg
    22561 ccccataagg actgtccaaa ctgtggtcac aaactcagta aaaacggaca ggatattccg
    22621 tttgagacct tccttggttt tgatggggat aaggttcctg atattgactt gaacttctcg
    22681 ggagaagatc agcctagcgc ccacttggat gtgcgtgata tctttggtga agaatatgcc
    22741 ttccgtgcgg gaacggttgg tacggtagct gccaagactg cctatggatt tgtcaagggt
    22801 tacgagcgag attatggcaa gttttatcgt gatgcagaag tagaacgcct cgctcaagga
    22861 gcggcgggtg tcaagcggac aacaggccaa cacccggggg gaatcgttgt tattccgaac
    22921 tacatggatg tctacgattt tacgcctgtc cagtatccag cagatgatgt cacggctgaa
    22981 tggcagacca ctcactttaa cttccacgat atcgatgaga acgtcctcaa actcgatgta
    23041 ctgggacatg atgatccgac catgattcga aaacttcagg atttgtctgg tattgaccct
    23101 aataaaattc ctatggatga cgaaggcgtg atggcactct tttctgggac tgatgtgcta
    23161 ggggtaacac ctgaacaaat tggaacgcct acgggtatgt tggggattcc agagtttgga
    23221 acaaatttcg tacgtggaat ggtagacgaa acccatccga caacctttgc ggaattgctt
    23281 cagctgtctg gtctgtccca cggtactgac gtttggttgg ggaatgctca ggatctgatt
    23341 aagcaaggaa tagcggacct atcgactgtt atcggttgtc gggacgacat catggtttac
    23401 ctcatgcatg cgggtctgga acctaagatg gcctttacca ttatggaacg ggtacgtaag
    23461 ggtttgtggc taaagatttc agaagaggag agaaatgact atatcgaagc catgaaggct
    23521 aataaggtgc cagagtggta tatcgaatcc tgtgggaaaa ttaagtacat gttccctaag
    23581 gcccatgcgg cagcctacgt tatgatggcc ttgcgtgtag cttacttcaa ggttcaccat
    23641 cctatttatt actactgtgc ttacttctcc attcgtgcta aggcttttga tatcaagacc
    23701 atgggtgcgg gcttggaggt catcaagcgc agaatggaag aaatctctga aaaacggaag
    23761 aacaatgaag cctctaatgt ggaaatcgat ctctatacaa ctcttgagat tgtcaatgag
    23821 atgtgggaac gaggtttcaa gtttggtaaa ttagatctct actgtagtca gacgacagag
    23881 ttcctcatcg acggggatac ccttatccca ccatttgtag caatggatgg tctgggggag
    23941 aacgttgcca agcaactggt gcgggcgcgt gaagagggag aattcctctc taaaacagaa
    24001 ctacgcaagc gtggtggact ctcatcaacc ttggttgaaa agatggatga gatgggtatt
    24061 cttggaaata tgccagagga taaccagttg agtttgtttg atgagttgtt ttaaaaaatt
    24121 gcttaataat ctattaaaag aggctaacgt atatccaata gatttacatt agctttcttt
    24181 tttgttaaaa tagtctatgg aaagagggtg agagtatgtc aaagatgagt ataagcatcc
    24241 gtctggatag tgaggttaag gagcaggccc aacaggtgtt tagtaatctg ggaatggata
    24301 tgacaacagc tattaatatt ttccttcgtc aggcaattca atatcaggga ttaccttttg
    24361 atgttagact agacgaaaat cggaagttgc tccaagcgtt aacggattta gaccaaaatc
    24421 gtaatatgag ccagtctttt gaatcagtct cagatttgat ggaggactta cgtgcttaag
    24481 attcgttatc ataaacagtt taaaaaagat tttaagttgg ctatgaagcg tggtttgaag
    24541 gcagaattat tagaagaagt tttgaatttt ctggttcaag aaaaagaaca tcctgccaga
    24601 tatcgtgatc attcattgac ggcatccaag cattttcaag gagtttgtga atgccatacc
    24661 cagccagatt ggcttttggt ttataaagta gacaagtcgg aattgatttt aaatttgctg
    24721 aggacaggca gtcacagtga tttattttaa tctattttaa gggggttctc atgaaactaa
    24781 gaatatttgc ggaagataag ccggctaaga aggtatttga atatcaatta gaacttgctg
    24841 atcgtacaat tcttctatcg acagcactct tgtcaggtgc tattgcttta gcaggaatct
    24901 tttctgcttt gagagaaaaa taaaaataga aaagagaaaa cagaatggtt ttaccaaatt
    24961 ttaaagaaaa tctagaaaaa tatgcgaaat tgttggttgc gaacggaatt aacgtgcaac
    25021 ctggtcacac tttggctctc tctattgatg tggagcaacg tgaattggca catctaatcg
    25081 tgaaagaagc ttatgccttg ggtgcgcatg aggtcatcgt tcagtggaca gatgatgtga
    25141 ttaaccgtga gaaattcctc catgccccga tggagcgttt ggacaatgtg ccagaataca
    25201 agattgctga gatgaactat ctcttggaga acaaggctag ccgtcttgga gttcgttcat
    25261 ctgatccagg tgccttgaac ggagtggacg ctgacaagct ttcagcttct gctaaagcta
    25321 tgggacttgc catgaagcca atgcgaatcg caactcaatc taacaaggtt agctggactg
    25381 tagcagccgc tgctggactt gaatgggcta agaaagtctt cccaaatgct acgagcgatg
    25441 aagaagcagt cgatctcctt tgggaccaaa ttttcaaaac ttgccgtgtc tacgaagcag
    25501 atcctgttaa ggcctgggaa gagcatgcag ctatcttgaa gagcaaggcc gatatgctta
    25561 ataaggagca attttcagcc cttcactaca cagcgccagg aacagattta acacttggtt
    25621 tgccaaagaa ccacgtttgg gaatcagctg gtgctgtcaa tgcacagggc gaaggattct
    25681 tgccaaatat gccgacagaa gaggtcttca cagcgcctga cttccgtcgt gcagatggtt
    25741 atgtcacttc tacaaaaccg cttagctaca acggaaatat catcgaaggt attaaggtaa
    25801 cctttaagga tggacaaatc gtagatatca ctgctgagaa gggtgatcag gttatgaaag
    25861 accttgtctt tgaaaatgcg ggtgcgcgtg ccttgggtga atgtgccttg gtaccagatc
    25921 caagtccaat ttctcagtca ggcattacct tctttaacac ccttttcgat gaaaatgcgt
    25981 caaaccactt ggctatcggt gcagcctatg cgactagcgt tgttgatgga gcggagatga
    26041 gcgaagagga gcttgaagct gcagggctta accgttcaga tgttcacgta gactttatga
    26101 ttggttctaa ccaaatggat atcgatggta ttcgtgagga tggaacgcga gtacttcttt
    26161 tccgtaatgg gaattgggca aattaaggag ataatatgtt aggaagtatg ttcgttggtc
    26221 tcctagtggg atttttagca ggtgctatga ccaatcgtgg agagcgaatg ggatgttttg
    26281 gaaaaatgtt tctcggttgg atcggagcct ttctaggtca cttgctcttt ggaacttggg
    26341 ggccagtttt atcaggaaca gctattatcc cagctgtttt aggtgccatg attgtcttag
    26401 ctattttttg gagacgagga agttaatttc ctaaatctga tactcaatga aaatcaaaga
    26461 gcaaactagg aaactagccg caggttgctc aaagcactgc tttgaggttg cagatagaac
    26521 tgacgaagtc agtaacatat atacggcaag gcgacgttga cgcggtttga agagattttt
    26581 gaagagtatg aaacgaaaag gaggttggtc attgtaccag cctccttttg atatgatata
    26641 atagttctat gagattagat aaatttttag ttgcctgtgc ggtgggaagt cggactgagg
    26701 tcaaaaactt gctcaaggct gggcgcgtga ctgtaaatgg taaaaaagaa aaatcagcta
    26761 aattgcagat tgatgaaaaa atagatgaga ttcgctttga tgggcaagtg ttggagtatg
    26821 aagagtttgt ctactacatg atgaacaagc ccaaaggagt tatctcagcg actgaggatc
    26881 ccaagcacag aaccgttctg gacttgttgg atgacttggc gcggagtaag gaagttttcc
    26941 cagtaggacg cttggatatt gacacgcatg gtcttttgct cttgaccaat aatggtcagc
    27001 tggctcatgt tcttctttcg cccaagcgtc atgtggacaa gacttatcag gctcaggtca
    27061 agggaattat gacccaagaa gatgtggaga catttatcaa gggcattccg ctcaaagact
    27121 ttacctgtca gcccgctaga ctggagattc tttccacaga tgcagaaaag aatcagagcc
    27181 aaatccgtgt gaccattgca gaagggaagt ttcatcagat caagcgtatg gtgggctact
    27241 gtggcaagga agtggtggac ttgcaacgat tgactatggg aactttagta ttagatgaga
    27301 acctggaacg aggggaatgg cgtcgcttga ccaaggaaga attagaaatt ctccgcgcta
    27361 atattattta atttagttta atactcaatg aaaatcaaag agcaaactag gaaactagcc
    27421 gcaggctgta cttgagtacg gcaaggcgac gttgacgtgg tttgaatttg attttcgaag
    27481 agtataaatt cgaaaaaggt gagggacaat gtcctcgcct tttatgtttt ttagttgctt
    27541 cctttgtgaa aagagttata atagactgta gaataaaagg aggaatctat gaacgcgatt
    27601 caagaatcat ttactgataa actatttgcc aactatgaag caaatgtaaa ataccaagcg
    27661 attgaaaatg ctgccagcca caacggaatt tttgcagctc tggaatgtcg ccaaagccat
    27721 gtagacaaca cacctgtttt ctcattggat ttaaccaagg acaaggtcac taaccagaaa
    27781 gcgtctggtc gttgctggat gtttgcggct ctcaacacct tccgccacaa actcatctcg
    27841 caatacaaat tggagaactt tgagttgtca caagcccaca ctttcttctg ggataagtat
    27901 gagaaatcaa actggttctt ggagcaagtc attgcgactt cagaccaaga attgactagc
    27961 cgcaaggtta gcttcttact ccaaacacct caacaagatg gcggtcaatg ggatatggtc
    28021 gtttccctct ttgaaaaata cggtgtcgtg cctaagtcag tttatcctga gtctgtttca
    28081 tctagcagca gtcgtgagct aaatgcgatc cttaataaat tgcttcgtca agatgctcaa
    28141 atcttgcgtg atttgcttgt ttctggtgca gatcaagcga ctgttcaagc taagaaagaa
    28201 gacctcttgc aagaaatctt taactttctt gctatgtcat taggacttcc accacgcaag
    28261 tttgactttg cttatcgcga taaagataac aactataaaa gtgaaaaagg aatcacacca
    28321 caagagtttt acaagaaata tgtcaatctt cctttagaag actacgtttc tgttatcaat
    28381 gctccaactg ctgataaacc ttacggaaaa tcttacacag ttgagatgtt ggggaatgtg
    28441 gttggtagcc gtgcagttcg ctacatcaac gttccaatgg agcgcttgaa agaattggcg
    28501 attgcccaaa tgcaagcagg tgagactgtt tggtttggtt ctgatgtcgg ccagctcagc
    28561 aaccgtaagg ctggcatcct tgcgacagat gtttatgact ttgaatcaag catggacatt
    28621 aaacttactc aagacaaggc tggacgtttg gactatagcg aaagcttgat gacccacgcc
    28681 atggtcttga caggtgttga cttggacgaa aatggtaaat caaccaagtg gaaggttgaa
    28741 aactcatggg gagacaaggt cggtacagat ggttactttg ttgcctcaga cgcttggatg
    28801 gacgaataca cataccaaat cgttgttcgt aaggaattgc tgacagcaga agaacaagct
    28861 gcctatggag cagaaacaat cgtacttaca ccatgggatc caatgggagc cttggctgaa
    28921 taaaagcata gaaaaaagga atcagatttt agaacctggt tcctttttag ttgcttgatt
    28981 acatgatgtg aagaacatgt gccacaatac ccactgcgaa gagggcaagg ataatagtga
    29041 ttggagatac ttttttctta agtaagtaca tgcaaagtaa agtaaggagt agtcctgata
    29101 atccaggaat caacatatcc aagttttgtt ggaaagtagt aactttttca ggagtttgag
    29161 acaatccttg tcctacttgt gcgaatgctt cttggatacc tttagaccct tctggcaatt
    29221 tatcccaatg gatataagcc ttttcatcta gttgaacttt agaaacatcg aaagcaaatt
    29281 taatatttac ccagcgttga acaaggacag caagaatgaa catcccaagg atagaagctc
    29341 ctttagtgat atcttgaagg ataccaccag acatatcttt agtgatttct gatccagcct
    29401 tgtatccaat ctcttgaaca taccacaaga atgacatacg aatcaagttc catgcaacaa
    29461 agaagaggag tggacccaag atattgccag taagggcaag tgaagcaccg agagatccaa
    29521 ggattgggcg cactgtaaac cagaatactg ggtcaccgat accagcaaga ggtcccatca
    29581 taccgatttt aaccccttgg atagcagcgt catcgatttc cacaccgtta gcacgttctt
    29641 cttcaagcgc aagagtaacc cccatgactg gagcagctac gtatggatga gtgttgaaga
    29701 actcaaggtg acgctcaaga gcagcgattt gatcttcttt tttagtatag agttttttga
    29761 tagctggaat gagtgtataa gcccagccca agttttgcat ccgttcaaag ttccaagacc
    29821 cttgtaagaa ggttgaacgc caccaaactt ttttacgatc tgatttagtt aattgaagtt
    29881 tttcagtcat gatgttttca gtcctttctt atcttagtag tcttctagga tatcgccgat
    29941 tgggtcgtta gaagttgcgg ctcctccgcc accatttcca ccagttttag aaaggtgaag
    30001 gtagataaga gcgatagcaa caccgatagc accgaatccg attagagtaa tatctgacac
    30061 agcagcgaga acgaaaccaa gagcgaagaa tggccatact tcacgagttg ccatcatgtt
    30121 gataaccatg gcgtaaccaa cggcaacgac cataccacca ccgatagcca taccatcttt
    30181 gagccagtct ggcatggcac taaggatact ttgtacagtt tcagttggta ccataaggag
    30241 aagagctgca ggaagcgcga tacgaagtcc ttggaaaagt agcgcaatga aatgcgcacg
    30301 ctccacagcg ccgaagtcac cttttttagc ggcagcatct gcagtatgaa ccaaaccaac
    30361 tgaaattgta cgaacaatca ttgtcaagaa aagtccagct acggcaagag ggatagcaac
    30421 cgcttgggca acaccgatac cagtcttggt aaagtcacca ccaagaacca tgataatggc
    30481 agcagcgaca gaagcaagtg cagcatcagg agcgatagca gcaccgatat ttgaccaacc
    30541 aagggcaatc atttgaagcg atccaccgag gataatccct gcttccaagt gacctgttac
    30601 aagcccaata agggtacagg ctacaagtgg ttggtgaaat tggaactggt cgaggatgcc
    30661 ttcaagacct gcaaagaagg ctacaacgac tactaaaacc atagaaataa tagacatgtt
    30721 taaaatcctt tcataaataa tggcttattt gacattggct ttgttaatca agtcaaacaa
    30781 atctttttta gaatcatttg gtactttacg gacatcaaat tcaacaccca agtcacgcat
    30841 tttttcaaat gtagcaacat cttctttgtc catagacaaa acggtattga ccaatgtttt
    30901 acctgttgag tgagccatag aaccaacgtt aagagtcttg attggcacgc cgccttcgat
    30961 ggcacgaagg gcatcttgag gtgtttcaaa caagataagg gcatgtgttt ctccaaaacg
    31021 tgggtctttt gaaatatcaa tcagtttttg aattggaacc acgttagcct tgacattacc
    31081 tggagctgct tgtttaatca attctttacg aaggtcgtct ttagccacgt tatctgaagc
    31141 aacgatgata cgatttgctt ttgaatctgg agtccaagca gttgcaacct gaccgtgaag
    31201 tagacgtgtg tcaagacggg caagattgat tttcaattta ccgtctccga taacagttcc
    31261 ttctgggata gcagcttggg caactggagc agctgcagcg cttgcaactt cttcaactgg
    31321 atttagctct tctggaagag ctttgatgcc atctttggct tctttaatga tattagcaac
    31381 gactttttct acacctgcag cagcgtccat gaggcgctct gtgtaggctt gaatcaacat
    31441 cggtaagtta agtcctgtga tgatggcaaa cttacgctca ggattttctc ccatcacgcg
    31501 actagcttgg ttaaatggag aaccactcca aaggtcagcc aaaactagaa cctcatcttc
    31561 tgcgtcaaat gcagcaacag cgttattaaa cttagcgtat agatcatcag gaccttcatt
    31621 tggcataaag gtcacaactt gaaccttttc ttgttcacca aagatcatag atcctgactg
    31681 atgaataccc gcagcaaatt cgccgtggct cgcaataatg attccgatac tcattattgt
    31741 cattcctcct tttttgtttt agttttcatt taagaaaact ttaagactgt ttaagtataa
    31801 accgttt
//
LOCUS       DAVKAU010000019        30921 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVKAU010000019 DAVKAU010000000
VERSION     DAVKAU010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30921
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.019"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(1..683)
                     /locus_tag="VWX48_001051"
                     /pseudo
     CDS             complement(1..683)
                     /locus_tag="VWX48_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1057..3024)
                     /gene="tkt"
                     /locus_tag="VWX48_001052"
     CDS             complement(1057..3024)
                     /gene="tkt"
                     /locus_tag="VWX48_001052"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9171690.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAVLPTFLGGSADLAHSNMTYIKADGLQD
                     KYNPLNRNIQFGVREFVMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQELP
                     VTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQATWHHALTSTTT
                     PTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELVL
                     QGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVIG
                     IDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            complement(3061..3756)
                     /locus_tag="VWX48_001053"
     CDS             complement(3061..3756)
                     /locus_tag="VWX48_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU9171691.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKATIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            complement(3767..4852)
                     /locus_tag="VWX48_001054"
     CDS             complement(3767..4852)
                     /locus_tag="VWX48_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEU9171692.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIVGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILRKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            complement(4878..5189)
                     /locus_tag="VWX48_001055"
     CDS             complement(4878..5189)
                     /locus_tag="VWX48_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU9171693.1"
                     /translation="MKIVGVAACTMGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            complement(5217..5666)
                     /locus_tag="VWX48_001056"
     CDS             complement(5217..5666)
                     /locus_tag="VWX48_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9171694.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            complement(5644..6072)
                     /locus_tag="VWX48_001057"
     CDS             complement(5644..6072)
                     /locus_tag="VWX48_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9171695.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKPPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            complement(6065..7528)
                     /locus_tag="VWX48_001058"
     CDS             complement(6065..7528)
                     /locus_tag="VWX48_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU9171696.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSKSVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFRMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSAFLTEGDKQRLQAKIQEINYE"
     gene            complement(8057..10393)
                     /locus_tag="VWX48_001059"
     CDS             complement(8057..10393)
                     /locus_tag="VWX48_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU9171697.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            10526..11275
                     /locus_tag="VWX48_001060"
     CDS             10526..11275
                     /locus_tag="VWX48_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU9171698.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTNKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            complement(11568..12182)
                     /locus_tag="VWX48_001061"
     CDS             complement(11568..12182)
                     /locus_tag="VWX48_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU9171699.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(12917..13186)
                     /gene="rpsO"
                     /locus_tag="VWX48_001062"
     CDS             complement(12917..13186)
                     /gene="rpsO"
                     /locus_tag="VWX48_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU9171700.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            complement(13327..13956)
                     /locus_tag="VWX48_001063"
     CDS             complement(13327..13956)
                     /locus_tag="VWX48_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU9171701.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            14812..14952
                     /locus_tag="VWX48_001064"
     CDS             14812..14952
                     /locus_tag="VWX48_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU9171702.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            14959..15135
                     /locus_tag="VWX48_001065"
     CDS             14959..15135
                     /locus_tag="VWX48_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU9171703.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            15193..17136
                     /gene="thrS"
                     /locus_tag="VWX48_001066"
     CDS             15193..17136
                     /gene="thrS"
                     /locus_tag="VWX48_001066"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU9171704.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAHEIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(17185..18159)
                     /locus_tag="VWX48_001067"
     CDS             complement(17185..18159)
                     /locus_tag="VWX48_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9171705.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(18152..18829)
                     /locus_tag="VWX48_001068"
     CDS             complement(18152..18829)
                     /locus_tag="VWX48_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9171706.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            18985..20058
                     /locus_tag="VWX48_001069"
     CDS             18985..20058
                     /locus_tag="VWX48_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU9171707.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            complement(20149..20451)
                     /locus_tag="VWX48_001070"
     CDS             complement(20149..20451)
                     /locus_tag="VWX48_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171708.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(20520..20957)
                     /locus_tag="VWX48_001071"
     CDS             complement(20520..20957)
                     /locus_tag="VWX48_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU9171709.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            complement(21033..21875)
                     /locus_tag="VWX48_001072"
     CDS             complement(21033..21875)
                     /locus_tag="VWX48_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9171710.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRHGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDGKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            21987..22637
                     /locus_tag="VWX48_001073"
     CDS             21987..22637
                     /locus_tag="VWX48_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU9171711.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNIDIAKQLYVEKIN"
     gene            22814..23491
                     /locus_tag="VWX48_001074"
     CDS             22814..23491
                     /locus_tag="VWX48_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU9171712.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKATIITYPVTFLIYTFAIKKWKASQE
                     GSPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIE
                     GNSNKEY"
     gene            23593..24006
                     /locus_tag="VWX48_001075"
     CDS             23593..24006
                     /locus_tag="VWX48_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171713.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFECLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            24080..24441
                     /locus_tag="VWX48_001076"
                     /pseudo
     CDS             24080..24441
                     /locus_tag="VWX48_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014307.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24480..24923)
                     /locus_tag="VWX48_001077"
     CDS             complement(24480..24923)
                     /locus_tag="VWX48_001077"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU9171714.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDVEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(24953..27175)
                     /locus_tag="VWX48_001078"
     CDS             complement(24953..27175)
                     /locus_tag="VWX48_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU9171715.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVYFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMIELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            28169..28798
                     /locus_tag="VWX48_001079"
     CDS             28169..28798
                     /locus_tag="VWX48_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9171716.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(28921..30813)
                     /gene="pepO"
                     /locus_tag="VWX48_001080"
     CDS             complement(28921..30813)
                     /gene="pepO"
                     /locus_tag="VWX48_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU9171717.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         9186 a         6993 c         5640 g         9102 t
ORIGIN      
        1 aatccgacga taagcataat ttcccttgtg ttcgataaaa atggattgaa tttcagcttt
       61 aagctcttgg tccttatctg gtttatctag ctgtttcaag tgatagtagt aggtcgaacg
      121 agctagttta atggctttta gaagaagatc taacgaaaac tcagtcatta attcttgaac
      181 aatttctgtc tttcttcttt ctctttttcc tccttcaatc ggagttctct taactttttt
      241 aggatggcat tctccgctct caggtactca ttttctgctt gaagacgttc tagttctgtc
      301 ctctcttcag gtctcttttt tggcttacgt cccattttag gtactctccc tcttgttttc
      361 tcaacaatag tatacccgtt tttcctgtat tgtgctagcc agttaagaag tatcgtacga
      421 cttgggagac cgtattcaag agaaactcta tctttagtcc agccttcatg tcagacttta
      481 ttactcattt cttgttttaa atcaggagaa tagtaacgat ttttcccttt tttgacgaac
      541 tctattccgt aacgatcaat caatttaatc atgtacctaa gattagaatt atttatccca
      601 aatttatttg aaagcttctc taagctatat ccttgttttc taagttcata gatctgaact
      661 ttatcatcat aagttaattt cataataaaa acaccccaaa agttagattt tttctgtcta
      721 acttttgggg tgcagttcat catttcaaca tcctatacta tgagtttttt aattttagag
      781 accttctctc tagctttcaa aaaacttaca atatcctaag tcaatctgtg gatgctgtgt
      841 ttattgatta aagaaactat ctagatcagt agcaaagtga ttagcgtact tcgcaaccgt
      901 ttcagggtat actctattgt gtatactatc tactataact ttcgtagata aattattaca
      961 ttctcattat agtttttaaa taaccaatca tctgattagt gtctatcact acatctgcta
     1021 gtctgacaac agctgtatct tcattgtaat tggtttctat agggacttaa cttgagcaac
     1081 gatattctct accgtaaatc cataattatc aatcacagtc tgagctgggg cagacgcacc
     1141 gaagatgtca ataccgatga ccgcgccatc caaaccaaca tacttgtacc aactttgggt
     1201 cgctgccatt tcaatggcca cacgacgacg agtcttagat ggtaaaatgt cttccttgta
     1261 ggtagcatct tgagcatcaa atagttcggt tgagggcata gataccacac gtactttacc
     1321 accttgtaaa accaattcct tagcagcttt gatagctaga ttgacctcag atcctgtagc
     1381 aatgataata gtatcaaatc ccggggtatc atacacgacg taggctcctt tagcgacctt
     1441 accaaagtct gtcccttctt caactaccaa gttttgacgg gttaagacaa tgacagttgg
     1501 agtggtggta ctggtcaagg catgatgcca agtcgcttga gtttcacggg catccgctgg
     1561 acggataaca gtcaagtttg gcattgagcg taaacctgcc aaatgttcaa ctggttcatg
     1621 agttggacca tcttcaccaa cggcaattga atcatgggta aagacataag ttacaggcaa
     1681 ctcctgaatg gctgatagcc gaatagcagc tttgacgtag tcagagaaaa caaagaaggt
     1741 tccgccataa actcgtaaac caccatgaag agccattcca ttgaggattg ttcccatgac
     1801 aaattcacgt accccaaact gaatattgcg gtttaatgga ttatatttat cttgtaagcc
     1861 atctgccttg atgtaggtca tgttggagtg agctaagtct gccgatccac ctaagaaggt
     1921 tggtaaaact gctgctgtat taatagcatc ttgggacgaa ttacgagttg cttgagagaa
     1981 gccattctca tagacaggga agtctttttc agtaatggtt acaggggatt ttccagctac
     2041 aatagcgtca atctcactag caacttcggg ataagcaacc ttgtaatcag acaccaaact
     2101 agcccaagca tcgtatgcct cctgaccacg atccgctaca tttgtcttga aatcagaata
     2161 tacttcctct ggtacttcaa atggatcgta atcccatccc aaaaacttac gagttgctcc
     2221 tgtttcttct gctcctagtg gtgcaccatg aacagcattt gtaccacttt tattgggtga
     2281 gccgtaacca attaccgttt tcacttcaat caaactcggc ttaccagaaa acttggccgt
     2341 ctcaattgct gtagaaattg ctgctaaatc tgttccatct tctaccagaa ctgtatgcca
     2401 accataagca tcgtaacggg cgcgaacatt ttcagagaaa gtatctttgg tctcaccatc
     2461 caagcagata tcgttggagt cgtagaggac gataagctta tctaaagctt gatgacctgc
     2521 ataagaagcc gcctccgcag acactccttc catgaagtca ccgtctccag cgataacata
     2581 agtataatgg tcaaaaatag gaaaaccatc tttgttgtac ttagcagcta aaaaacgctc
     2641 tgcttgggcg aaaccaacgg cagtagaaat cccctgacca agcggaccag atgtcgcatc
     2701 cacaccagac gtatgcgtca cttcaggatg accaggtgtc ttagatcccc attgccggaa
     2761 atttttaatc tcgtccatgg atacatcctt ataccctgtt aaatgcaaga gagcatacag
     2821 tagcattgat ccatgacccg cagacaagat aaagcgatct cggttaatcc agtttggctg
     2881 ctcaggtgta attctaaggt gctttgtaaa taggctataa gccattggcg cagcacccat
     2941 gacgattccc gggtgaccag aattagattt gttaatagca tctacgccaa gaaaacgaat
     3001 ggcgttaact gattgtagtg acatatattc ctcctaacta ataaatttct tctcaaacca
     3061 ttatttgatt ggcattgttt ttccggtcat ttcttcgtaa tctctagaac agatatccca
     3121 ggctttggca atatcgtcat ccaaaccaaa taatccactg cgacctataa cataaatatc
     3181 tggtcctgcc acatcaattt gtttgaaagt cttacgactc gaagaaccat ccatctcaat
     3241 gatgtagtga taaccattct gaactctaag ctgacggagt tcttggattt tatacaaggt
     3301 agactccaaa aagcgttgtc ctgcaaaacc tggatctaca gtcataatag ttgctttgtc
     3361 aagtaaatca atgtagggaa agattgtaga aacaggtgtt tcaggattaa ggacaacacc
     3421 agcctttaga cctgcatcat gaattttatc aatcaaacga aaagcaagac cattcagaac
     3481 ttcagcatga atacaaatat actcacattg taaatcgaga acttgatcta cccaaaaggt
     3541 tgggtctgtg accatcagat gaactgataa aggtgtgtca ctaatttttt gaacttcttg
     3601 aatgaaccaa ggagacaagg taatattggg aacaaaatgg ccatccataa tatcgatatg
     3661 ataagatgct actttatcat tcaaaaaagt aatctgctct ttgaatttgt ccaaatccat
     3721 ggtcatcaaa gatggtgaaa attcaattct tgacatcgtt accctcttac aaaatttcaa
     3781 tatctgacaa atcaatctct tcttcaacag tcataactgg ttctgtatgt tttattggtt
     3841 ttctcaaaat cgcgtagaca agtcctgtga ctacaatgtt ggctaacaaa gcacaaatac
     3901 cagctactgg acgagtcatg gttggtaaca taagcactcc accaaatggc acggcagaat
     3961 cagcacccat tgtcaaagaa acagcaccac caacagcacc accgatacct gttgcaatga
     4021 gacctggaac caagttattc ataacaatcg gaattacacc ttcaacaata ttgacaatcc
     4081 ccataggaac agccgatttc aatgtttcga tttcctcttg agtatagata ttttttttga
     4141 gtaatttcgc gataaaatag gccaatccaa atccaactgg tgtagcagta ttcaccaatt
     4201 gcaaagcagt caatggttct ttcacacctt cagcctgtaa agtcaacaca aacgcataga
     4261 ctgttttatt aagtgggcca ccaaagtcaa cagcactgag aactccaata actgccccca
     4321 tcaaaccatt tgaagcactt cccaagcttt gtaataagct cgtcaaccag ttggtaaagg
     4381 ctgcgatagg cgccccaata atataaatca taatcaaact acttaccaaa gaggctacaa
     4441 aaggaataat caaggttggc attaaacctt taatccagtt tggtactttg acctttttaa
     4501 taatcgcttg aaccaagaaa ccaactatat aacctcccaa gataccaccg ataaaccctg
     4561 aaccaacaga attggcaatt agaccaacaa caaaacctgg tgcaatccct ggcttaccag
     4621 caatcgagta agacaaacct gtagcaataa caactggcaa gagaccaagg gctttaccac
     4681 ccatagttgc taaagcatcc cagatagtga attttcctgc tacaagagcg tcaggaacac
     4741 caccccccat tgctaaacca atggcaacta agaatcctgc accacaaaca attggaatca
     4801 tataggaaat ggctgtcaat aagtgacctt ttaagtttaa gtgtttcaac atatattttc
     4861 tccttaaata ttttcagtta tttcgtaaca atctcaacag ctttagcaat cagtttattg
     4921 ggagatttga ctgccacttc tgttggaacc ttgataatct ttttaccctc aaagcgttcc
     4981 ataccagaaa tcttaacatc aactgctaaa ataactacat ccgctgcatc aatctgctct
     5041 tgactcaatt cattttctac ccctattgtc ccctgagtct caacatgaat cacatgtcca
     5101 gctacctttg cggcattctc taatttttcc tgtgcaatat aagtgtgggc aattcccata
     5161 gtacaagctg caacaccaac aattttcata cggataccct ccaaaatttt ttcttattaa
     5221 caaaaagctg caatcacatc atcagatgtc tgagcccgaa ctaatttggc aacaacttcg
     5281 tcattaccaa gttttcgagc aaagagtgat aaggtcttca aatgctccct agcagcttct
     5341 gtatcatcac caactgcaaa gagtacaatt actttgaccc ctttcccatc aatggtctcc
     5401 caaggaatct cattgtgatt tatagctatg actacccccg ccttctccac agcagaactc
     5461 ttgctatggg gaatagcaat ataattccca ataccggtct gtccttctgc ctctctctga
     5521 taaagacctt cgataaattg gtctctatca gacacataac ccgtctcaac caatagttga
     5581 gctaatgcct caaaaacctc ttctttgctc tgcatctgta aatccgtctg gatcagactc
     5641 acattaagaa tatctttgat ttccatatat tatctcccgt aattcttctt ttgttaactg
     5701 ttttaattga tttatgaatg attcatctgc tagtcttctc atcaatgttt taatacatga
     5761 cttgtcctgt gatactgcaa tggccaaacc gataataagg tcaacacact ggatatcctt
     5821 cgaccattct ctgataggtg gttttaatct agtaatcact aagacatgat gttgaaagtt
     5881 tccttcacaa tgtggtagaa gaacaccttt agcaacctct atacttccct gtctctcacg
     5941 gtaatataga agctcttcta ttttttctgt atcttcagaa acaagaaggc tgatttgatt
     6001 tgctaattct ttgtaggctt cttgacgatt ttgaacagat atatccataa ggacaagcga
     6061 aagattattc atagtttatc tcctgaattt ttgcttgaag acgttgttta tcaccctcgg
     6121 ttagaaaagc actaactagg acaaacggga cacttgctgg ttcctgcaaa gctaccgtcg
     6181 tcacaatgaa atctaaatct ggatatagat ttatcagctc atctaattga tgataagcaa
     6241 ctacatcaat aatatccaat tcagaaaatt gcttttctaa tcgtgctcgt aaaagctctg
     6301 aagttccgac acctgatgta cacatcacta ctgtttttag aggacgtgct cgcttttctt
     6361 gaaaccgtgc aaaatataag actagaaaac caatctcgtc cagactcaag gacgcaaaac
     6421 caaatactag actcacttct ttagaaatag ttgttaactc tttaaccaga ttaggatagg
     6481 ttaaaagaat ttgtgataaa agactattct taatctgtac tctattatct aatctcctca
     6541 gtaagggact gatatgactc gccaagtcaa caaagtcagg atctgtcgtt tcaatctctc
     6601 tattgtccat acacatacgg ctaaaatagt aatgagtgac atctaaaact cgctgagaaa
     6661 aaggaagctt cccggaagaa aatggttttt gcaatctcga agatacaacg tattgataaa
     6721 gatagtcaat ctcaactgca tcaaccttca tcctaaaata ttgttcaatt tcttgaataa
     6781 ttttttgaca gacactgtaa attttctcat caacaatagt aggttttgaa ggtgctacaa
     6841 catgaatact agtactacga cgattcctac tgataaaaat atacaggtga gagaaaatat
     6901 ttatattata tggataggga atgtttaccc ccaattctct ctcaagtgta atcagtaatc
     6961 ccaaacaaaa gtgagcaagt tctccgtcaa gaggctgaac cttattctgt gtaatttgct
     7021 ctaaatccaa ctgattaaac attggcagta gatttagaat ggctgaacga atttgagcct
     7081 catccccatc aataaaaagc tttcgttgtc tcatttttaa atctaaccca taaattgcta
     7141 gactctcttg taatatctga cgatctttta gtactactga cttgcttacg tagaattcct
     7201 ctcctaaatc ataaatagaa tgtggcttag gagcagtcaa caagagacgt tctagtaatt
     7261 tttcacgcct tacttcagga tcaaaagcct ctgtaaaatt cccatcaacg tccacgaggg
     7321 aacttcttgg atttaatttg aaacctctgc ctttttcaga taaaatgaat gcttctaccg
     7381 gacaatcttt gttgattccc ttgacaaggc gataaaccgt tttatcagag caatttaatt
     7441 tttctcccaa tactttagca gatatataat ccttactatc tcgcaaaagg agcaacaacg
     7501 tttccatttg ttcttgtttt ctagacacga tacacctcct ttatgattcc attatatcgc
     7561 tttcaaaaaa taatatactt cgcattttgt cctttgcaat ggacattttt gtttttgtca
     7621 aaaatatgat atcaaataga acagaacctc actatgccaa aatcatttta ccttttcttc
     7681 ataacatcta ttttagttga aatatttaag ttgcttttcg tatttgataa gaaataaacc
     7741 aaacgatttt ctaataaata acactatgtt ccatttaaca atagatagca tcttcatttt
     7801 caaactacca acttatccga ccatttgttc tagcaataga agagagttaa aattacttca
     7861 atctgtcgct ttctctttct tacatcaaac ttcaaatagt ctaactacag atatttgaat
     7921 ctattacctc aatccaagca ggcttgagaa tcactcttgg gttcaccgat agatgatcgg
     7981 cacgtaggcc ttgcacatca gatctacgat agatccatcg tataaaaaac tgcaatccac
     8041 agattgcagt ctttctttat tttctagctt gatagcgact agtcaggatg aaaatcactg
     8101 taaagaccaa catcatgaca ccataaacag gcaacgtttg ttctgtcaag gttgaaattt
     8161 caagcagttt ttggattctt gggaagagag ctgtggctag gaagcctcct actgaccaga
     8221 caatcaagag gactcgccat agagtgaatg gcatgcaggc tctaaatacg gataagaaac
     8281 caattgaccc caagagataa tagaggagag ttgagatttc taactcagac caaccttgac
     8341 tcgttccaaa gattttcaca aaaagaacgc taaacacgac catgagggca cttggtaggg
     8401 cacgaagcat ggatcttctg aggaagtttg gctcgacagg tttgatattt cgctcaaaag
     8461 tcaaaacgaa tggtgggaaa ccttccacaa actggtcaat catggtaatc tggattggaa
     8521 tgaaggggaa aatcaagatc cattcagacc gacctagtaa agcactggcg atacagataa
     8581 ctgcgagcaa gaatgagtag atggtcttta tcaagaaaat cggagcgatg tgggcaatgt
     8641 tattgaccac acgacgacct tcaaaaagaa tctcaggaac atcattaaag tctgagttca
     8701 agagaaccag gttggcaatc tgacgggttg ctggatcccc ctccgccatt acgatagaac
     8761 aatccgcctc acgaagagcc aggatatcat taactccatc cccagtcata gctgttgtat
     8821 gacccgcttt tttcagcgtt tggataatga gtttcttttg atgaggggaa acacgtccga
     8881 aaatagctgt ctcctccgcc atggccatca attcctcatc ggtgattttt gagcaatcta
     8941 catagctgtg atagtccgca aaaccagcct tctgggcaat gctggacacc gtaactggat
     9001 tgtcaccaga gataatcttg agtcccacct cctgagaacg gagatagtcc agcgtctctg
     9061 ctgctccctc tcgaatgggg tccaagattt ccagcaaggc tagagcctga atatcagatg
     9121 gtttctgtgg tttgtgatgg tctaatttct cctgactgag agctaagacc aagacacgtg
     9181 atcctctctc caaggcctcc ctggcttctg ggacttcaga atccagcaac atctcaggtg
     9241 cccctaagaa aactgtcccc aagccttcta actccatagc cccccacttg cggtcgctgg
     9301 agaagggaag attggaaatc ataggataag caacatctcc cacaaaacgc tggcgaatgg
     9361 cttgggcagt tggattctta tcctcactat gggccatata gctggtcagg atgctggcaa
     9421 cagcctcttc accgtaagtt tccgtcagtg gaagaacagc ctccacctgc atctttcctt
     9481 gggtgatggt gcccgtcttg tccagacaga gcatatccac gcgcgccaag gtctcaacag
     9541 agtacatctc ctgcaccaag acctttttca agcccaactt aatcactgca gtcaagagcg
     9601 aagtaatggt caaaagggca attcccttag gcaacattcc caaaagagct gtcgacgagt
     9661 ttacaacgga tgacttgaga ggcaggcctt ttaaaagcaa ggcttccagc aagagagcca
     9721 gaccaaaggg aatgataatc ttcccagtaa aaccagccaa cttgtccagc gatttcatga
     9781 tacgggagtt gatgggttta acggtcttag cctcaagcat gagtttggca gcatagttgt
     9841 ctgcaccgac atggtgaact tgagataaaa ctgacccact ggctaggaaa cttcctgaca
     9901 aaagtaagcc gtcaacttcc ttttgcacca aatcactttc tcccgttaac atggcttcat
     9961 tgacttccgc aaagccttcc aaaaccaagg catcactagg aatctgctct cctgcagaca
    10021 aacgaatgac atctcctagc actaattctt caggattaag agcaacttcc tgaccatcac
    10081 ggatggtttt gaccttttcc ttggtcatga gattgagctt gtccaccatg tgtttggctc
    10141 gtagctcggt cacaatccca gaaaaagcgt taaagcagat aacagcaaag aagaccagat
    10201 tgctccaagc ctgcacaaag gcaagggcca aagcaatggc aaagttcaaa gcgttaaaaa
    10261 gggtaaagac atttcgttta acgatttgcc aagtgctggt actggctgat gcggtaaagt
    10321 cattgaccaa accctcagcc tgtctttcct tgatttctct ttgggttaat cccataatct
    10381 tatttttatc cataaattct attatatcat tttttttaac agaattctaa tttcatccca
    10441 aatatgcatc tagtcaaggg aaaagtttgc cagccctcct ttgataaggt ataataataa
    10501 caagaaaaca atcgaaggag atcgcatgtt ttatacttat ttgcgtggat tagttgtatt
    10561 gctcttatgg tccatcaatg gcaatgctca ctatcataat actaataaaa ttcctaatca
    10621 agatgaaaat tatattttag ttgcgcctca ccgtacctgg tgggatcctg tttatatggc
    10681 ctttgcgacc aagccaaaac agttcatctt tatggcaaaa aaagaactct ttaccaaccg
    10741 tatctttggt tggtggattc gtatgtgtgg cgcctttccc atcgaccgtg aaaatcccag
    10801 cgcctcagcc atcaaatatc ctatcaacgt tctcaaaaaa agtgaccgct ctctcatcat
    10861 gtttccaagt ggtagccgcc actcaaacga tgtcaagggg ggcgcagcac tgattgccaa
    10921 aatggccaag gtccgtatca tgccggttac ctacaccggt cccatgactt tgaagggctt
    10981 gattagccgt gaacgtgtcg atatgaactt tggaaatcca atcgatatct cagatatcaa
    11041 gaaaatgaat gatgaaggca ttgaaacagt cgccaatcgt attcaaacag aattccaacg
    11101 tctggacgaa gaaacgaaac aatggcacaa tgataaaaaa ccaaatccac tctggtggtt
    11161 tatccgcatc cctgccctca tccttgctat tatcctcgct atcctaacca tcatctttag
    11221 ctttatcgca agcttcatct ggaacccaga taagaaaaga gaagaacttg catagaagaa
    11281 atgaaccttg gccaaacagc taaggttttc atttatatag tagattggaa ctagaatagt
    11341 acacctctac ttctaaaaca tttttagaaa tcgatttgac tgtcctgatc gattttgtcc
    11401 tattcttatt tcattttact atatttataa gaatccccta atcaaatcaa aagccactct
    11461 acaatagagt aactttaaga ttgtccattt atactcaatg aaaaagccct ctgaaaatca
    11521 gagagctgat ttgagctcag gctaaaatcc tagtgaaaca aaaaaatcta cacgatcaga
    11581 aaagtctcta tcgtgccatt ttcatacatg atgtatagtc caagtagaat gaatactaag
    11641 ggcacaatga ttcgctcgta tttttcaatt gtctcgaata ttaacggaat agaggataac
    11701 accctactaa tctcgcaaaa gataattatg ccgattacaa acacaagcaa ggccacgagg
    11761 gtctgtgacc aatctaacga agcaaaataa ggtatataga tacctaaatt atctccgcca
    11821 gacgcaattg tcagcaatgt aactgtccaa aacagttgat ttgccttgct ttgttctaat
    11881 ctttcaataa tttcttcctc ttcttcttcc gcatcttctc caacaattgc aaagcgaatc
    11941 cctaaataga tagggattaa accaagcaat ccaaccatcc attcttcagg cacgaaatta
    12001 acgacataag cagcaactaa actcgcccct acaagtaagc ctgtgcctag atattgcccc
    12061 gcataaatat gccatttctg tttattctgt gatagctgtg caaataaaat aattaaaata
    12121 attaaataat cgatactggt ggaaatataa acaccaatag cagatatgat tgtctgtccc
    12181 ataaaaaaaa cctcctgtat tagtcagtaa taaatcagca gattttagga gagcacagac
    12241 acattaattt agctatcgct agtgggtaat gtcgaacgta ggaaagcatt ttactcctcc
    12301 tcaaaacgta gttacaaagt aatttctaac tggaattcag tgactacttc catgtaaagt
    12361 ataacatact atactttact ttgtaaagag tgggctcttc tagggggctt gcatacagct
    12421 actcggcttg aaaagccgag taactgcgca cctttatggt gtaattagct gataccgttt
    12481 gaggtttttg tagtctccaa aattgttacc gataaaacct caataaaaaa gccctctgaa
    12541 gtcagagagc tgatttgagc ccgggctaaa atcccagtga aaaagatgaa actccttgtg
    12601 ctcatcgaac actgtgtcat ttccctattt tcatacggat ttttgacgcc cttagcatca
    12661 tgattcttgc tagataaatc gtttatagac taggcgacga ggcgaagatc gtacgaaact
    12721 ttcagtgaaa caaaaaaaat ctccccgaag ggagaaaagc tggtttattt taccttacag
    12781 tgctaggaac cgtaaccaaa gattatactt gagtatatcg aggtaaggtg acaacgcaaa
    12841 aaagctaccc aatttagagt agcttcatta tcaagatatg ctcaattgaa cacggcctaa
    12901 gcacttgtat cttgaattag cgacgaagtc ctagagagtt gatcaactca cggtaacggt
    12961 taacgtcgtt tttacgcaag tatgcaagca agttacgacg gcgaccgatt tttttcatca
    13021 atccacggta agtagcgtgg tcttttttgt gttgtttgat gtgttcgtta aggtggttga
    13081 tttcccaagt aaggacagca acttgaacct ctactgaacc tgtatcacct tcgtgacgtg
    13141 catattgtgc aatgatttca ttttttttct cttttgagat tgccatgatg tttctccttt
    13201 ttatttggct tcatccgagt gacaggttgg catgcctgta accaagaaga agttatttgt
    13261 ctttacgaca atccctattt taccaagatt taaattttct gtcaaacatt aatactctca
    13321 tagttattat ttttcaagta aagagatacg ttcttttata tgatgacctt tttcaagttc
    13381 atctaccaat ccaatagcat aatctgcata actaatctgg cttattcctt tttcattagt
    13441 agtaaaaatt tctcctgcta gaatgtagtt tcctgttttt tcaccatcgg gaataaaatc
    13501 tacagcagga ctgacaaaag tccagttgag attatttttt gtacgaagaa gatccaattc
    13561 atccgcttga tcttttgcta gtgacttaaa ttcttcagga aaatcagacg tatctaaaag
    13621 tcgtgtcgtt tttgtttcat ctatataaag acttcctgct ccccctacaa ctagaaaacg
    13681 tgtctgtgtt ccagcaagaa gctgattaaa tagttcgatt gatttgctgt ggagcggtag
    13741 cgtatctggt gtataagcac caaacgctga aataacagca tcaaatccag taagatcatc
    13801 ttttgtcaac tcaaataaat cttttttaat aatagactca gcttgacttt tgttttcaga
    13861 acgaacaata gccgttactt catgtcctcg tttgactgct tcttcaacaa ttgctttccc
    13921 cgcttgtcca tttgctgcaa taactgctag tttcattttt tatacctctc ttgttgtaat
    13981 tattttagtt acaacaattg tgacactttt aataatcaat gtcaatagtc ttgcttaatt
    14041 attatcaaaa tatttctacc aagaaaacta accatgattc tagtgaaaaa aatcttcttt
    14101 gtcaacaaat ttactttctt gttttaaata tgctataata atcatagcaa gagatctaag
    14161 ttgtctgttt ttttaaaacg aggtgattat catgcgtaga ttctattccc atctccccta
    14221 ctatctggtc atattattct tttattggcc actttatgag ttgttcttgc tagttgtttc
    14281 tgaccccctt acactatata aacaatcttc tcttctttac acctctggta atcttgattg
    14341 tatcgttact ctatagctac cgtttccgtt tctcactttg atggttagtt ggtaacggac
    14401 tgctctttta ctttactatc ataacctttg gtgagtttat actaatttac ttgctaatct
    14461 atgaaacagt tgctctggtc ggcatggatt ctggtattag catcaagcat attctacaaa
    14521 aaatgaaaaa caaaaaactt tcacaaaatc cttgaaaaat ctcacaatca tgctataata
    14581 atccatagag acaagtcact tagtcccttt ctactagaga gtgcgtggtt gctggaaacg
    14641 cataggaagt ctaaactgat actactcttg agttttttat gaaaacataa aacggtggcc
    14701 acgttagagc caatcagagg tgtccctctc ttttgaggta cataaatgaa ggtggaacca
    14761 cgttgcgacg tcctttcgag gatgtcgcat ttttttatta ggatactaat tatggagttg
    14821 caagaattag tggagcgcag ttgggcaatc cgacaagctt atcacgaact ggaagttaag
    14881 catcatgatt tcaagtggac ggtagaagaa gacctcttgg ctttatctaa tgatattgga
    14941 aatttccaat gactggtgat gacaaagcaa ggacgctact atgatgaaac accctacaca
    15001 ctggaacaaa aactttcaga aaatatctgg tggctattag aactttctca acgtttggat
    15061 atagacattc tgacggaaat ggaaaacttc ctctctgata aagaaaagca attgaacgtt
    15121 aggactcgga agtagtctgc tgataaaaaa tcaatgctta gaaactatga aataataaaa
    15181 aaggagaaca tcatgattaa cattactttc ccagatggcg ctgttcgtga attcgaatct
    15241 ggcgtaacaa cttttgaaat tgcccaatct atcagcaatt ccctagctaa aaaagccttg
    15301 gctggtaaat tcaacggcaa actcatcgac actactcgcg ctatcactga agatggaagc
    15361 atcgaaattg tgacacctga tcacgaagat gcccttccaa tcttgcgtca ctcagcagct
    15421 cacttgttcg cccaagcagc tcgtcgtctt ttcccagaca ttcacttggg agttggtcca
    15481 gccatcgaag atggtttcta ctacgatact gacaacacag ctggtcaaat ctctaacgaa
    15541 gaccttcctc gtatcgaaga agaaatgcaa aaaatcgtca aagaaaactt cccatctatt
    15601 cgtgaagaag tgactaaaga cgaggcacat gaaatcttca aaaatgaccc ttacaagttg
    15661 gaattgattg aagaacactc agaagacgaa ggcggtttga ctatctatcg tcagggtgaa
    15721 tatgtagacc tctgccgtgg acctcacgtt ccatcaacag gtcgtatcca aatcttccac
    15781 cttctccatg tagctggtgc gtactggcgt ggaaacagcg acaacgctat gatgcaacgt
    15841 atctacggta cagcttggtt tgacaagaaa gacttgaaaa actaccttca aatgcgtgaa
    15901 gaagctaagg aacgtgacca ccgtaaactt ggtaaagagc ttgacctctt tatgatttca
    15961 caagaagtgg gacaaggttt gccattctgg ttaccaaatg gtgcgactat ccgtcgtgaa
    16021 ttggaacgct acatcgtaaa caaagagttg gcttctggct accaacacgt ctacactcca
    16081 ccacttgctt ctgttgagct ttacaagact tctggtcact gggatcatta ccaagaagac
    16141 atgttcccaa ccatggacat gggtgacggg gaagaatttg tccttcgtcc aatgaactgt
    16201 ccgcaccaca tccaagtttt taaacaccat gttcactctt accgtgaatt gccaatccgt
    16261 atcgctgaaa tcggtatgat gcaccgttac gaaaaatctg gtgccctcac tggccttcaa
    16321 cgtgtacgtg aaatgtcact caacgacggt cacctattcg ttactccaga acaaatccaa
    16381 gaagaattcc aacgtgccct tcagttgatt atcgatgttt atgaagactt caacttgact
    16441 gactaccgct tccgcctctc tcttcgtgac cctcaagata ctcataagta ctttgataac
    16501 gatgagatgt gggaaaatgc ccaaaccatg cttcgtgcag ctcttgatga aatgggcgtg
    16561 gactactttg aagccgaagg tgaagcagcc ttctacggac caaaattgga tatccagatt
    16621 aaaactgccc ttggaaaaga agaaaccctt tctactatcc aacttgattt cttgttgcca
    16681 gaacgcttcg acctcaaata catcggagct gatggcgaag atcaccgtcc agtcatgatc
    16741 caccgtgggg ttatctcaac tatggaacgc ttcacagcta tcttgattga gaactacaag
    16801 ggggccttcc caacatggct ggcaccacac caagtaaccc tcatcccagt atctaacgaa
    16861 aaacacgtgg actacgcttg ggaagtggcc aagaaactcc gtgaccgcgg tgtccgtgca
    16921 gacgtagatg agcgcaatga aaaaatgcag ttcaagattc gtgcttcaca aaccagcaag
    16981 attccttacc aattaattgt tggagacaaa gaaatggaag acgaaacagt caacgttcgt
    17041 cgctacggcc aaaaagaaac acaaactgtc tcagttgata attttgttca agctatccta
    17101 gctgatatcg ccaacaaatc acgcgttgag aaataagagt ctagcataaa agcctccaat
    17161 ctggaggctt tttctcatct atttttactc aaggactaag ttcacttgag caaactgaat
    17221 ccgcactgtc gttccttttc cgacctcaga ctcgatacga atctggtgcc ccagttcttc
    17281 agaaattttc ttagatagat aaaggccaag tccagaggac tgctgggtca aacggccatt
    17341 gtatcctgaa aagccacgtt caaatactcg gaggacatca ctgtttttta tcccgattcc
    17401 cgtatctttg atacaaagct cttggtcatc catataaatc tccagaccac cttccttggt
    17461 gtacttgaga ctgtttgaga tgatttgctc aataaccact agcagccact ttttatccgt
    17521 cacgatttct ttatcaaggt catgtagatt gacatttaag cctttttgaa taaagaaaag
    17581 agcatattta cgaattattt ccttgaccaa gtcctcaatt tgaacctgct ttaagagcaa
    17641 atcatcatgg aaactttcta aacgcaggta ctgtaaaact aggttggtat aggagtcgat
    17701 tttgaaaatt tcctgttcta gctgctgctt cagttggcgg tcgaccactt ctgcaactaa
    17761 gagttgactg gctgcaatgg gggtctttat ctgatggacc cacaaggtat agtaatccag
    17821 caaatccgtc agttttcttt ctgcttttga cctctgctga tagagttcca tctcacgcgc
    17881 ttctaatttt tctgctaaag ctatttccaa aggagacttg gcttccctct ctccatagag
    17941 aagttcctgg cgatagacct gcgtttccac caatatgtcc caagtgaaaa ataagatggt
    18001 tacaaagcaa cacaagaaga aaaagtagag gaagtaaatt cctagactgg caaataaaaa
    18061 ctgaaagagt aagacaagaa atgccaaaga aagcagatag ataaaaagac gactacggga
    18121 gcgcagatag gctagaaaaa attgtttcca atcaagcatg cttcaatccg taccctattc
    18181 ctttcttggt ctcgataaat cctaccaatc cctgctcctc caacttttta cgcaaacgag
    18241 ccacattgac agagagggta ttatcatcaa tgaaaaagtc actgttccaa agttcccgca
    18301 tcaggtcgtc acgtgctacg atgttgcctg catgctcaaa taacacgcgt aaaatctgga
    18361 attcattctt ggtcaaattc aagacttgcc cttgataatg taaatccatg gatttggtat
    18421 tgaggataac accagcatat tccagcaaac tctcatcacg cccaaactca taggaacgac
    18481 gcaacaagcc ctgaacctta gctaaaagaa cctgctggtc aaaaggcttg gtcacaaagt
    18541 catccgcccc catattgatt gccatgacaa tatccatagc ctggtctctc gaagaaagaa
    18601 acatgatagg taccttggaa atcttgcgga tttcctgaca ccagtgataa ccattaaaca
    18661 agggcaaacc aatatccatg aggaccagat gaggttccga ctgaacaaat agactcaaaa
    18721 cttccataaa gtcttctacc aggaccactt caaatcccca ttcagagagc attttcccaa
    18781 tctgttgacg aatgacctga tcatcttcta ttaataaaat cttgtgcatg cgcttctcct
    18841 tttccattat tataacagat ttttccatgc tagatggtct gaaactgaat ttgaaatagc
    18901 ctgtttttag ccagtacaaa caggctatgc tactagctaa tttgagggaa atttgctaag
    18961 ataaataaaa agaaaggagc tcttatggcc aatatttttg actatctgaa agatgtcgca
    19021 tatgattctt attacgacct tcccttgaat gagttagaca ttctaacctt aatagaaatc
    19081 acctacctct cctttgataa tctggtctcc acacttcctc aacgtctttt agatctagca
    19141 cctcaggttc caagagatcc caccatgctt actagcaaaa atcgccttca attattagat
    19201 gaattggctc aacacaagcg cttcaaaaat tgcaaactct cccattttat caacgacatc
    19261 gaccctgaac tgcaaaagca atttgcggct atgacttatc gtgtcagcct cgatacctat
    19321 ctgattgtct ttcgtgggac agatgacagt atcattggct ggaaggaaga tttccacctg
    19381 acctatatga aggaaattcc tgctcaaaag cacgcccttc gctatttaaa gaactttttt
    19441 gcccatcatc ctaagcaaaa ggttattcta gctgggcatt ccaagggagg aaatctcgct
    19501 atctatgctg ctagccaaat tgagcaaagt ttgcaaaatc agatcacagc agtttataca
    19561 tttgatgcac ctggtctcca tcaagaattg acacagactg cgggttatca aaggataatg
    19621 gatagaagca agatattcat tccacaaggt tccattatcg gtatgatgct ggaaattcct
    19681 gctcaccaaa tcatcgttca gagtactgcc ctgggtggca tcgcccagca cgataccttt
    19741 agttggcaga ttgaggacaa gcacttcgtc caactggata agaccaacag tgatagccag
    19801 caagtagaca caacctttaa agaatgggtg gccacagtcc ctgacgaaga acttcagctc
    19861 tacttcgacc tcttctttgg cactattctt gatgctggta ttagctctat caatgacttg
    19921 gcttccttaa aggcgcttga atacattcat catctctttg tccaagctca atccctcact
    19981 ccagaagaaa gagaaacctt gggtcgcctt acccagttat tgattgatac tcgttaccag
    20041 gcatggaaaa atagataata ctcttgaaaa ttaaatgtat acaaaacaaa agacctagaa
    20101 tacatacttt catgtgcatt ctaagtcttt ttaaatagaa tctaatagtc aataaaaatc
    20161 aaagagcatt gagagataat ggggcttgga acgtccctct cgcttcaaca aaatgacccc
    20221 attatagatt aaaaagatgc cacttagaaa aagcaaaaaa ggaagtaaga caaaggtaaa
    20281 tacataaaaa gctaactgaa cattctcgta tccattttta taaaaaaggt aggatagata
    20341 aaaataactt gaaatgaggg ataataaaaa taatactgga ttccacaaac ttctattatc
    20401 cttccaaaat gacactataa aggctaatac aatttctata acgagataca tttcttactc
    20461 ctttaatagc tacattttat cataattatc caaagaaaaa aagagggcat ttatccctct
    20521 taatccttca tctgactctc tgcatcggcc acgacttttt ctagactggt ctgaccaagt
    20581 tctgcctcca tagtcaactg aattctctcc aatttttgat ccaaaacatc atgaatatga
    20641 gctcctacag ggcaatttgg attcggattg tcatggaaac tgaagagttg acctgtctta
    20701 ccaagacatt cgaccgcctg ataaacatct aaaagactaa tatccttaag gtccttgaca
    20761 atctctgttc cgcccgttcc acgcgctact gaaatcagct ctgccttctt caactgggac
    20821 aagatctttc tgataatgac aggattgacc ccgacactag cagccagaaa atcactggtc
    20881 accttgcttt ccttcccctc gagggcaatg attatcagca tatgagtcgc aatggtaaat
    20941 ctacttggaa tttgcatcct cttctccttt ttacgaggct accctgcctc tactcttctt
    21001 tttctattat tatacccttt ttagttgtaa tgtcaatcgt taccactttt caaccagtcg
    21061 tctaactccc gatcgcaacc ctctttctga gccaattctc tcaaaaattc ctgatgatga
    21121 gtatggtgga tcccattgac cagactttca tagtaaacct caaaataggg aagtctcagg
    21181 tctttagcca gctgcaattc agctgccaca tcgtagtcta cccgtcggaa gtccatatct
    21241 accaggccct tgccatcaaa ctccaaaatc atatactggg cccgcaagtc cttccgtagc
    21301 tgagcgtcca aaaagaaagg ttggccaatc gaacccggat tgacaatcaa ttgcccacca
    21361 gtcccgtgac gaagcaactg ctggtgaata tgtccataaa cagcaatatc acagggagga
    21421 tgagtcacca agcggtcaaa atcctcttgt ttgccagtat gaatcaactc tcgcccccag
    21481 ttcttatcag gcagatgatg gctaattccc actgtcaaat ccccaaactg acgatgaatt
    21541 tgaagaggtt gattgtggag cacttcaatt tcttctaggg aaatttcctc taaaacatac
    21601 tggcactggc gcaagagata gcgttgacta gggcgagtac tatccaattc cttacggaca
    21661 ccatgccaaa gactgtcttc ccagtttccc aaaactctag ccgtaatcgg tagttgatcc
    21721 aacaagtcca aaatccttct acgtcctgtc cctggcatga gaatatctcc caaaagccag
    21781 tattcatcca ctcctagctg ctgagcatct gccaaaacag cctccaaggc ggtggtattt
    21841 ccatgaatat ctgaaagaag agctattttc gtcatatcca tctcctcgtt ttttctcttg
    21901 caataagtat aacataaaaa gtcacagcta gagaaatcta gctttttttg atatactaga
    21961 taaagatatt agacaagagg aaacgaatga ccccaaacaa agaagactat ctaaaatgta
    22021 tttatgaaat tggcatagac ctgcataaga ttaccaacaa ggaaattgcg gctcgcatgc
    22081 aagtctctcc ccctgccgta actgaaatga tcaaacgaat gaaaagtgaa aatctcatcc
    22141 taaaggacaa ggaatgtggc tatctactga ctgacctcgg tctcaaactg gtctctgagc
    22201 tctatcgtaa gcaccgcttg attgaagttt ttctagttca tcatttagac tatacaagtg
    22261 accagattca cgaggaagct gaggtcttgg aacacactgt ctctgacctg ttcgtggaaa
    22321 gactagataa actgctaggt ttccctaaaa cctgccccca cggaggaact attcctgcca
    22381 agggagaact cctcgttgaa atcaataacc tcccactagc tgatatcaag gaagctggcg
    22441 cctaccgcct gactcgggtg cacgatagtt ttgacattct ccattatctg gacaagcact
    22501 cacttcacat cggtgaccag ctccaagtca agcagtttga tggcttcagc aataccttca
    22561 ctatcctcag taacgacgag gatttacaag tgaatataga cattgcaaaa caactctatg
    22621 tcgagaaaat caactaattt ctcaagtccc ctaccaaccc tgaaagtttt attttcaggg
    22681 ttttatttct atcatttgat tttactttca tttggtggta gagtatttga aaaaaagaaa
    22741 ggtagtttaa cctatgaaaa aatcactaaa aatttttgct acatctaaat gatttgacct
    22801 cttcggggtt gctttggtcg ttgggattgc gattgcatct ggttatctca actcacgcct
    22861 cgataaattt gtagactggg gactatggac agctcttgta ccctttggat tgatttccgt
    22921 aaccaacgtt gggatttcca tgttgtccac tcgtttcacg gggaaattaa gcaaatgggg
    22981 aaattacttt ggtattgtta ataccatttt gtccggtgct attgattata tccttggaaa
    23041 taaggcgacc atcattacct atcccgtcac cttcctcatt tatacctttg ctataaagaa
    23101 atggaaagct tcgcaagaag gcagccccaa ccaaatgagc caaaaacagg taaaattggc
    23161 ggccatcatc atttccatca tcgccttcct ctttgccttt gtaaccaact atatcggata
    23221 tgggggcaag atgaatctcc ttgcctacgt aacaactatt gcctttgcac tgtccctcat
    23281 tgccaatgct ttgaatgcat tgaaactaac aactcagtgg ggcttttggt tgatttacaa
    23341 tttcgttcag ctgacaaaag ctggtattca aggaaacttc gccaatatcg gtaaatacat
    23401 cttttatatc ctcaatgcaa tcggagcttt atttgtctgg aatgatgaag aagttagata
    23461 catagaagga aactcaaata aagaatacta gccaacttaa gagaatctcc cttctgctat
    23521 ttttatcatt ttagttgtaa ctcccattct tttggagtag aatgaagtta gataaaagag
    23581 gaaggtcttg tcatgaaaaa actctataga atccatttta tagcaattgc agttattgat
    23641 ttgctactat ttgcattttt tatcactaga ctcgagacat cttttgagtg cctcttgctc
    23701 tctggtttaa ttttcttcct tgctcaagga ctcctgctat ttctcttggt cgtccgactc
    23761 aaacatcaat tcgctgagat ttatcctcaa atcaataaaa agattcgctt ctactattta
    23821 ggggttctca ccattgattt tctatttttt gttctcttag ccttcattag ttctcagcgt
    23881 ttttcatctc ttatgccaat tatcactgct tgccattcta ctttttatta tatgacagct
    23941 gactacctag gagaaaacta tccagacttt tacgacaaac acatctcttt atgggagtgt
    24001 ctctaaggaa aaggaggttt tagcatgaaa aaaaatcatc ttcatcaaaa ccattcaact
    24061 ccttgtcatt gatggaatca tgctggcatt tttgacattt aaaaaggggg gcttacttgg
    24121 gactggattt tgatttatag cggttggctc attttctttc atcctgtgct attgacctat
    24181 ctttcaaacc aactttgtga ccactttagt caactctatt cccagattag accgagattc
    24241 tggcgttttg ctttacaaat tctcctatgg gatagcctga tgattctctc cttggtgtct
    24301 ttaagtgata ttccactttt ccttcaggga actctcctca tcctaggaca tctcatccct
    24361 tcctatcgca tctgccaaag cctgaaaaga gacttccccc aagcatatca agaaccgatt
    24421 tctttttgga gtattttatg atcgatgaga aagaccaagc cgactgggct tggtctttct
    24481 tatctctttt tagtatctag gataatggta acaggtccgt tattaaccag ctcaacctgc
    24541 atatctgctc caaagatacc tgtctgaacg ggcacttctt gcgctaattt ttgattgaaa
    24601 gcatcataga agtctgatgc catatcaggt ttagctgccc ctgtaaaggc tggacgattg
    24661 cctttcttag tatccgcaaa gagggtaaac tgagaaatag agaggatttc tccttcaata
    24721 tctttgacag acaggttcat cttgccttct acgtctgaaa aaatccgcat attgaccagt
    24781 tttctcacag catagtccaa atcttcctct tggtcctctg gtccaacacc aaccagcaat
    24841 aaaagtccct gattgatttt tccctgaatc tggccttcta tactcacttg ggctttttta
    24901 acccgttgga taatgatttt cataatagcc tttctagtaa gagctaggac aactagccgt
    24961 tggtccgttt gacagagtaa acttctggca cactcttaat tttatcgaca accgtggtca
    25021 gtgtagagag gttggcaata ccgaaggaca catggatatt agcaaacttc atatccttgg
    25081 ttggttgggc attgaccgtt gaaatattct tggttgtatt tgaaagaact tgcagtacat
    25141 cgttcaacag tcctgtacgg ttgagaccgt agatatcgat atgggccata tactccttat
    25201 ttgagctaga gtactggtct tcccattcca catcaaggag acgttgctcg tagttttctt
    25261 gggcacgcag gttcatacag tccacacggt gaatagccac accacgaccc ttggtaatgt
    25321 agccaacaat atcgtcacca ggcacggggt tacaacactt agcaatccgc actaggagac
    25381 cagaagcacc ttcaataacc actcccccct catgcttgac cttgagagtt tctttatttt
    25441 caaccttgac ctcgccacct ttgacaagct cctctgcctc agccttggcc ttggcacgct
    25501 cttcctcacg gcgttctttt tcagtcagac ggttaaagac ggtaatcgca ccgatttccc
    25561 caaaaccaat ggccgcaaag agggagtctt ctgtcttgta actggtcttt tgcagaactt
    25621 gatccatgtg gcgcttgtcc ataaatttat ttgccacata gccattttct tggaactgag
    25681 ccatcagcat ctcacgaccc ttgttgacag acaattcctt atcttggttt ttaaagaact
    25741 ggcgaatctt attgcgcgcc ttgctagtct tgaccatatt gagccagtca cggctaggtc
    25801 caaaggagtt cgggttggcg ataatttcaa cctgatcccc tgtctttaac ttggttgtca
    25861 gtggaaccat gcggccattg accttggcac cagttgcttt ttcaccgacc ttggtatgga
    25921 tttcgtaggc aaaatcaatc ggtcctgaat ctttgggaag agaacggaca gctccatctg
    25981 gggtaaaaac gtaaatctcc tcagccagat agttttcctt aacagagtcc acaaattcct
    26041 tagcatcatc agcctggtct tggagctcta tcatctcctt gatccagttc attccaatag
    26101 ctgattcctt gctgttaact tgccccttta tacctttctt ataagcccag tgagccgcaa
    26161 ccccgtactc agccacctcg tgcatttcct tggttcgaat ctggaattca atcggccctt
    26221 ttggtccata aacagtcgta tggatagact gataaccatt ggccttgcgg ttggcgatat
    26281 agtctttgaa gcgacctggc atcggtttcc aaaattcatg cacgtaacca agcatggcat
    26341 aaacatcact ttgggtatct aaaatacaac gaatagcaat cagatcatag atttcctcaa
    26401 accgttttct cttgtcctgc attttgcgga aaattgagta aatatgcttg ggacgaccat
    26461 aaatcttccc tttcaagtga cgttctgtcg tatactcctc taattttgtg actacctcat
    26521 ccaccaaggc ctcacgctcc ctgcgctttt ccttcatcat atgggtaatc ttgtaaaact
    26581 ccgttggatt gagataacgg aaagacaagt cttctaattc ccatttgaca ctggaaatcc
    26641 ccaaacgatg ggcaagcggg gcatagattt ccatggtttc tttggaaata cgctcctgct
    26701 tgtcttttcg aagatgtttc agggtccgca tattgtgcaa gcggtcagac agtttgacca
    26761 aaataacgcg gatgtcctca gacatggcca tgagcatctt gcgatgattt tccgctaatt
    26821 gctcctcgat cgatttgtac tcgaccttgc caagcttggt aactccgtca acaatcatcc
    26881 gcacatcagg accaaactct ctttccaaat cgtccaaggt cgcatctgta tcttccacca
    26941 catcatgcaa gaatccacaa gctactgtta cagcatccag ctttagctta gctaaaatac
    27001 ctgccacttg gatagggtga atgatataag gctcgcctga tttgcgatat tgaccactgt
    27061 ggcattcaac agcatagacc aaggccttat ggacaaaata aacatcctct tccgttaaat
    27121 attctttggt taaagcgaca acttcttcgc ctgttaaatt cacttctttc ggcatctcta
    27181 ctctccaatt cttcctacca ttttatcact tttttaagaa tatgaaaact agattggaac
    27241 agaataagaa aaaaataatt caaaattgct tgataattct gaattattgg cccataatat
    27301 actacgaagt tagattttaa acttaggtga tagaaggaga gatagaagaa cggaaaccat
    27361 attgtaaccc aaagactttc tgatttcccc aattccattg aagatacgaa agataaacgg
    27421 tggaactcgt atcacataca ctggtacctt gactggattt tggaattaat actcaatgaa
    27481 aatcaaagag caaactagga aactagccgc aggttgctca aagcactgct ttgaggttgt
    27541 agataagact gacaaagtca gtcacatata tacggcaagg cgacgttgac gcggtttgaa
    27601 gagatttttg aagagtataa aaatcctcaa gatactttct tctatccttt agtttataag
    27661 gagaatacct atgaaaaaaa ctgctatttc tatctttgct ctcctaatgt taggagtttg
    27721 ctgcctgttc ctattcagcc agcaaagcta taaaaaactc gttcaatact atgctaacga
    27781 ccagaacctg cccagtagga taacttatag tgaatatagc gacaaatgag aagccaacta
    27841 cggtagcact ctaaacatca cgtctatcaa acaagctaat gacggagttt atgcaaccta
    27901 tgaagggcaa ttgacacctt tccaatattg ataaattgat aaccagcctg tcttcatcta
    27961 gtcatgctgg tttttaagtt cattttaaat ccttacctat tctccctaac tgtgctatac
    28021 ttaatttata ctcaatgaaa atcaaagagc aaactagaaa gctagccgca ggctgttcaa
    28081 agcactgctt tgaggttgca gataaagttg acgcggtttg aagagatttt cgaagagtat
    28141 tagtacattc tttgagattg gagctagtat gaaaatccat aaaaccgtga atcctgttgc
    28201 ctatgaaaat acctattatc tagaaggcga aaagcacctc atcgtcgtcg atcctggtag
    28261 tcattgggaa gccattcgtc agacaatcga gaagatcaac aaaccgatct gtgctattct
    28321 cttgacccac gcccattatg accatatcat gagtctggac ttggttcgcg agacgtttgg
    28381 caatcctcct gtctatatcg cagagagcga agccagctgg ctctacactc ctgtcgataa
    28441 tctctccggt ctccctcgcc acgatgatat ggcagatgtg gtcacaaaac ctgcagaaca
    28501 cacctttgtc tttcacgaag aataccaact agaggaattt cgttttaagg ttctaccgac
    28561 cccagggcac tctatcggtg gtgtttccct agtctttcct gatgctcacc tagtcttgac
    28621 gggagatgct ctattccgcg aaactatcgg acggaccgac cttccgactg gtagcatgga
    28681 gcaactcctt catagtatcc agacccaact cttcacccta ccaaactacg atgtctatcc
    28741 aggacatggt ccagctacta ctatcgctca cgaaaaggcc ttcaatccct ttttctagca
    28801 agatgatgac aatcgaaatt taagtaaact atccagcaaa tctttctatt acaaaaggca
    28861 tcctatcaag gttttcacac gtgattggat gccttttttc tgatgactag attttttgta
    28921 ttaccaaata atcacgcgct cctctggtga acgccacatt ccgtctcctt ctttgacatc
    28981 ataggttgta aagaaatcgt cgaagtttgg tacttgcaca ttgacacgga gtttggctgg
    29041 tgcgtgcaca tcgacgctag ccaaaagttt cataaattct ggtcgacctt tcatgcgcca
    29101 gatgcgaccg aagttgtaga agaactcttc tgctgagaag tctgcttctc tcttagctgc
    29161 ttcaagcgct gctgcgattc ctcccaagtc agccacgttt tctgatacag tcaatttacc
    29221 gttaatggtt gctccataag aatcctgtcc atcaaattgg tcaatgactt tttgtgtttt
    29281 ctccttgaag gcagcatagt cgctctctgt ccaccaatcc ttgaggctac cattttcgtc
    29341 aaaggaagcc ccgttagtat caaaggcgtg ggaaatttca tgggcaatca ctgccccaat
    29401 accaccgtag ttagcagaag atgactgatg caagtcatag aaaggcgcct gtaaaatggc
    29461 cgctggaaag acaatcaggt tcttctgagg attgtagtag gcattgacca tatgagcagg
    29521 catgccccat tccttataat ctacaggctg gttccactta ctccaactgt gcttgatttc
    29581 cacacgcgca aaggctagag cattctcaaa aagactggca gtttcattca ctaccttatc
    29641 cttgtaacgt gcaggcaatt cttctggata gccaatataa ggtttgatca cattgagctt
    29701 cacgatagcc tgtttacagg tttctggagt gagccagtca ttcttaagca gacgctcctt
    29761 ataaacatca atcatggttg ccactttttt ctccacatcc gccttggctt ctggagagaa
    29821 cttctcacgg gcgtaccaaa gacccagggc ttgcttgaaa ggttcttgtg ctagatgata
    29881 agctgctttg accttatctt ttgcctctgg aactccagaa agggcacggc tgtaggcacc
    29941 agacaaaaca cggatatcct ctgttaaata gctggttgaa agattgacaa cactcaaaat
    30001 caaggttgct ttaaggagag accaggcttc ctcactgtag aattgctctg ctgcttgcca
    30061 gaaacgttcc tcgtctacaa taaccttgtc tggtaattgc ccaataactg ctttgaagaa
    30121 gtcatccaaa ggtagggcag gcgcgaattt cttgaaatct tcgtaagaat atggatgata
    30181 gagtttagca tattctgaac tttcttcatt agagagcacc actgtcgcaa ctcggcggtc
    30241 caattcaagt cttttttcta gcaagtcttc aatttcttca tcagagaaat cataagcctt
    30301 gaggagattt gcgctgcttt ctttccaaag agtcaagagc tcttcgcgct gaggatgttc
    30361 ttctgcatag taggtcgtat ctggcaagat tgtgcttgga gcgctagccc atagaacatt
    30421 gattctagca tccataaagt ctggcgatac accaaaagga aggaagtttg gttttcctgc
    30481 aagctcaaac tctgctagtt tagctgtaaa atccgcaaaa gtctccaatt cttggaattc
    30541 tttaaggagt ggtaagacag gtgtgatacc gtcagcttct ctcttgtcaa aatcacgaac
    30601 taggcggtgg tatttgacaa agttttccaa gatagcatcc tcaggcactt cttcacctgc
    30661 taaccacttg tctgttgtcg ccagcatcag gtcttcaatt tcctggtcta aatcaacaaa
    30721 acctcctgtt tgagacttat ctgctgggat ttcagctgtc tgttgccatt ctccattgat
    30781 agcatcataa aaatcatctt gataacgtgt catcttgttc tcgctttcat ttgtatttgc
    30841 atttatctta acaaaaatca ctagggaatg caattaataa ccatttaact attatttttt
    30901 agctattata aaaaatcttt c
//
LOCUS       DAVKAU010000020        29109 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVKAU010000020 DAVKAU010000000
VERSION     DAVKAU010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.020"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(117..1136)
                     /gene="adhP"
                     /locus_tag="VWX48_001081"
     CDS             complement(117..1136)
                     /gene="adhP"
                     /locus_tag="VWX48_001081"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU9171718.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVARLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(1475..2287)
                     /locus_tag="VWX48_001082"
     CDS             complement(1475..2287)
                     /locus_tag="VWX48_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9171719.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKNPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            2477..3895
                     /locus_tag="VWX48_001083"
     CDS             2477..3895
                     /locus_tag="VWX48_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU9171720.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            3949..4656
                     /locus_tag="VWX48_001084"
     CDS             3949..4656
                     /locus_tag="VWX48_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9171721.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQMSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     SWGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            4750..5724
                     /gene="folP"
                     /locus_tag="VWX48_001085"
     CDS             4750..5724
                     /gene="folP"
                     /locus_tag="VWX48_001085"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU9171722.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLITEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            5726..7048
                     /locus_tag="VWX48_001086"
     CDS             5726..7048
                     /locus_tag="VWX48_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9171723.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLFDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQDSVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRVYLMERKNENGYTKD"
     gene            7029..7583
                     /gene="folE"
                     /locus_tag="VWX48_001087"
     CDS             7029..7583
                     /gene="folE"
                     /locus_tag="VWX48_001087"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU9171724.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            7626..8438
                     /gene="folK"
                     /locus_tag="VWX48_001088"
     CDS             7626..8438
                     /gene="folK"
                     /locus_tag="VWX48_001088"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU9171725.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(8483..8800)
                     /locus_tag="VWX48_001089"
     CDS             complement(8483..8800)
                     /locus_tag="VWX48_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU9171726.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            9155..9601
                     /gene="rplM"
                     /locus_tag="VWX48_001090"
     CDS             9155..9601
                     /gene="rplM"
                     /locus_tag="VWX48_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU9171727.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            9620..10012
                     /gene="rpsI"
                     /locus_tag="VWX48_001091"
     CDS             9620..10012
                     /gene="rpsI"
                     /locus_tag="VWX48_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU9171728.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            10403..10741
                     /locus_tag="VWX48_001092"
     CDS             10403..10741
                     /locus_tag="VWX48_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU9171729.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDKHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            10931..12367
                     /locus_tag="VWX48_001093"
     CDS             10931..12367
                     /locus_tag="VWX48_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9171730.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSLAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAVHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            12419..12658
                     /locus_tag="VWX48_001094"
     CDS             12419..12658
                     /locus_tag="VWX48_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU9171731.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGTIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            12788..13102
                     /locus_tag="VWX48_001095"
     CDS             12788..13102
                     /locus_tag="VWX48_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU9171732.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            13220..15199
                     /locus_tag="VWX48_001096"
     CDS             13220..15199
                     /locus_tag="VWX48_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9171733.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKFGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMVQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEEKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            15209..15523
                     /locus_tag="VWX48_001097"
     CDS             15209..15523
                     /locus_tag="VWX48_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU9171734.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            15554..16060
                     /locus_tag="VWX48_001098"
     CDS             15554..16060
                     /locus_tag="VWX48_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171735.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKVYQQFVQ
                     LEKNSLSL"
     gene            16140..17486
                     /gene="celB"
                     /locus_tag="VWX48_001099"
     CDS             16140..17486
                     /gene="celB"
                     /locus_tag="VWX48_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU9171736.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANSATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            17867..18043
                     /locus_tag="VWX48_001100"
     CDS             17867..18043
                     /locus_tag="VWX48_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171737.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFRSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            18444..20657
                     /locus_tag="VWX48_001101"
     CDS             18444..20657
                     /locus_tag="VWX48_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU9171738.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDSLWLLNHYHYQDSCKNAEGGLTLSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVQTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDVSNI
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(20879..21355)
                     /locus_tag="VWX48_001102"
     CDS             complement(20879..21355)
                     /locus_tag="VWX48_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU9171739.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            21578..24781
                     /locus_tag="VWX48_001103"
                     /pseudo
     CDS             21578..24781
                     /locus_tag="VWX48_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            25162..25538
                     /gene="tnpA"
                     /locus_tag="VWX48_001104"
                     /pseudo
     CDS             25162..25538
                     /gene="tnpA"
                     /locus_tag="VWX48_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(25926..26555)
                     /locus_tag="VWX48_001105"
     CDS             complement(25926..26555)
                     /locus_tag="VWX48_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU9171740.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDKSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPSSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(26565..27566)
                     /locus_tag="VWX48_001106"
     CDS             complement(26565..27566)
                     /locus_tag="VWX48_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU9171741.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIQPNMLDMDSLFQGISHFHFSGITVAIGQEVRTILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(27597..28238)
                     /locus_tag="VWX48_001107"
     CDS             complement(27597..28238)
                     /locus_tag="VWX48_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU9171742.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(28257..29072)
                     /locus_tag="VWX48_001108"
     CDS             complement(28257..29072)
                     /locus_tag="VWX48_001108"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU9171743.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT         8998 a         4933 c         6251 g         8927 t
ORIGIN      
        1 ttatttttgt atgttgatat gttgagtttt tgaggagtaa tcttgaattc ttatttaaaa
       61 tttaatataa aaaagttgga agaagcttcc aacttttaaa ataggtttct attagattag
      121 tgggtgaagt cgagtaccat acgtccttgg atttggcctt tttccatttc gtcgaaaatg
      181 gcaacagcat cttctactgg acgtttttga acaactggga ctaccagacc ttctgcacca
      241 aattggaagg cttcttctaa gtctttacga gttccgacaa gagaaccgat gacttggatt
      301 ccatcgagga ctgttttaac gatgctgagt tccatcattt cagaaggaag accaacagcg
      361 acgacgcgac caccagcacg aatggagtca acagcctggt tgaaggcaac tttagacaca
      421 gcagttacga cagctgaatg agctcctcca tcagtttttt ctttaatgag tctagctaca
      481 tcttcaactt cgaggccgtt aatcacaatg tcagcgccta cttcttttgc aagggcaagt
      541 ttgtcattgt tgatatcgac tgcgataaca tgagcattga atactttttt agcgtattga
      601 acagcgaggt taccaagtcc accagcaccg taaagaacaa cccattggcc tggttcaact
      661 tttgcttctt tgatagcttt ataggttgtt actccagcac atgtgataga agaagcttgg
      721 gctggatcaa gtccgtcagg aaccttgaca gcatagtcag cagttacgat acattgttca
      781 gccataccac cgtctactga gtagccagca tttttcactg tacggcaaag ggtttcgcga
      841 ccagttgtac agtattcgca agtgccacat ccttcaaaga accaagcaac gctgacgcgg
      901 tcaccgactt taaggctttt cacatctgga gcaatctctt taacgatacc gataccttcg
      961 tgcccaagaa cacgtcctgg gacttgacca aagtcaccat gagcaacgtg gaggtcggtg
     1021 tggcaaacgc cacagtattc aacttctaca agtgcttccc cagtttcaag tggacggagt
     1081 actttttctt caatagcaac accagtgctt tctggattta caacaacagc tttcatagct
     1141 atcctccttg atattgaccg agaacaggga caacgggact ggattgattt tttgtcaaca
     1201 gagtcgagtg tgacgagctc tcttgtattt atatgtgaag tatatcacaa aagaaagcct
     1261 tttccaaggt tttggagaca aaaagtagaa caatcgatta actggttgat gagactgtga
     1321 aaagagcaca aagaccagct tgcaagctgg tcatactctt cgaaaatctc ttcaaaccac
     1381 gtcagcttca tctacaacct caaagcagtg ctttgagcaa cctacggcta gcttcctagt
     1441 ttgctctttg attctcattg agtatcagta taggttataa gaataagtct tgtagggttt
     1501 tggcaacccc atcttggtcg ttggtaaggg aaatttgctc atctgcataa gggagtagct
     1561 ctggattggc atttttcatg gcataaccct tcccagcaaa agcgagcatt tcggtatcat
     1621 tgtgttcatc tccaaaggca atcaaatctt ttttgtcacg attcattatc ttgagcaagt
     1681 agtccaaagc aaaggccttg ttgacacctt ttggggtaca ttcaaggata ttgagcggac
     1741 ctccccaggt attgatagaa agttgatgct ggtagaaggc gttcatgtct tttgccaagg
     1801 catatttgtc actggctctg gtctgcaaga ggatacagtt agggttcttg gtcaccaatt
     1861 caggctggaa ttgatcttca ggctggaaag cttctacacc aaatagtttg ggattggcaa
     1921 tttcttcatt gggatttgta atgtagaatt ttttacgata ttctccagcg ataaaatcgg
     1981 cttgaatgtc ctctgaacgt tgaaccatat ctagcagata ttttttgtct acagtcaaac
     2041 acttttcaaa atcccaaact tggtctggta aatgagtaag ggatccgttg aagttaatca
     2101 taggagtgtc taagcccagt tcacggtaaa aatcttttga catacggtaa gggcgacctg
     2161 tcgtaataat aacctgatgg cctttttcag caactttttt gatggttttt ttggtaaagt
     2221 cagaaatttg actgtctgag ttgagcaggg ttccatccag gtcaactgca ataatttttt
     2281 tcgtcatatg gacctttcta gtgtgttttc agataagatg tcttctatta taacagaaag
     2341 caggcagaaa agcagattcc aaacaaaaaa tgaaattgga ttaatttctt aaacaaatca
     2401 aacaaagaca ttgaaaaagt gaatgataaa tgatataatt ctattattgt tcgtaaaaat
     2461 taaaaggaga ttgatgatgg acaaattatt taaactaaaa gagaacggta cagacgttcg
     2521 tacagaggtt ctcgctggtt taacaacttt ctttgcaatg agctatattc tctttgtaaa
     2581 cccacaaata ctttcacaaa caggaatgcc tgctcagggc gtcttcctag cgacgattat
     2641 tggtgcagta gcgggtacct tgatgatggc tttttatgct aacttacctt atgcccaagc
     2701 gccaggtatg ggactcaatg ccttctttac ctttacagtt gtattcgggc ttggttattc
     2761 ttggcaagaa gccctagcta tggtcttcat ctgtgggatt atttcattga ttattacctt
     2821 gacaaatgtt cgtaaaatga tcattgaatc gattcccaat gctcttcgct cagctatttc
     2881 agctggtatc ggtgtcttcc ttgcctatgt agggattaag aatgctggac ttttgaaatt
     2941 cacgattgat ccaggcaact atactgttgt aggagaaggg gctgacaaag ctcaagcaac
     3001 gattgcagca aactcttcag cagttccagg attggtcagc tttaataatc cagctgtttt
     3061 agtggctctt gcaggacttg ccattactat cttctttgtc atcaaaggga ttaaaggggg
     3121 aattattctc tctatcttga caacaactgt tcttgctatt gcagttggtt tggttgattt
     3181 gtctagtatc gattttgcta ataaccatgt tggtgcagct tttgaagatt tgaagacaat
     3241 ctttggtgca gctcttggtt cagaaggttt gggagctttg gtttcagata cagctcgctt
     3301 gcctgaaact ctgatggcca ttcttgcctt ctcattgaca gatatttttg acacaattgg
     3361 taccttgatc ggtacaggtg aaaaagttgg tatcgtagcg acaaatggtg aaaatcacca
     3421 atcagccaaa ttggataagg ctctttactc tgatttgatt ggaacgacag tcggtgccat
     3481 tgcaggtact tcaaacgtaa cgacttatgt tgagtctgct gctggtatcg gtgcaggtgg
     3541 acgtactggt ttgacagcct tggttgtagc tatctgtttt gcgatttcaa gcttctttag
     3601 cccacttcta gcgatcgtac caacagcggc tacagctcca atcttgatta tcgttgggat
     3661 tatgatgctt ggtagcttga aaaatatcca ttgggatgat atgtctgaag cagttcctgc
     3721 cttcttcaca tctatcttta tgggattcag ctactctatc actcaaggga ttgcagttgg
     3781 tttcttgact tacactttga ctaagcttgt taaaggtcaa gttaaagatg ttcatgtcat
     3841 gatttggatt ttggatgcct tgtttatcct taactacatc agcatggcct tataatagaa
     3901 tgacccaggg ggatttcccc ccttttttaa tacaaaagga gataggtgat gaaagagaaa
     3961 aatatgtgga aagaattgtt gaatcgtgca ggctggattt tggtcttttt acttgccgtc
     4021 cttttatatc aggttcccct agtggttacc tctattttga ctttaaaaga agtagccctg
     4081 ctacagtcag ggctgatagt tgctggcctt tcaattgtgg ttctggctct atttattatg
     4141 ggagctcgta aaaccaagtt agctagtttt aatttttctt tttttagagc taaagatttg
     4201 gcacgtttgg gcttgagtta tttagttatt gtcgggtcaa atatacttgg ttccatttta
     4261 ttgcaaatgt caaatgagac gacaacagct aaccagtctc agattaatga tatggttcaa
     4321 aatagttcgt tgatttccag tttcttcttg ctagccttgc ttgctccgat ttgtgaggaa
     4381 atcttgtgtc gtgggattgt tcctaaaaag atttttcgag gcaaagagag ctggggattt
     4441 gtagtcggta cgattgtgtt tgctttatta catcaaccaa gtaatttacc ttctttattg
     4501 atttatggag gtatgtcgac agttctatct tggacagcct acaagaccca acgtttggaa
     4561 atgtcgatct tacttcacat gattgttaat gggattgctt tctgtttgtt ggctcttgtg
     4621 gtgattatga gtcggacatt agggatttct gtttaagatt attgacaatt gcttacttgt
     4681 ttctactggg agaaagatga atgaaatcgt gtccatcttt ttctttttat ggtaaaatag
     4741 agaaataata tgatgaaaag ccttgaggga gtgaccgata tgtcaagtaa agccaatcat
     4801 gcaaagacag ctatttgcgg aattatcaat gtaaccccag actccttttc ggacggtggt
     4861 caattttttg ctcttgagca ggcgctccag caggctcgta aattgataac agaaggagcc
     4921 agtatgctcg atatcggcgg agaatcgact cggccgggaa gtagctatgt tgagatagaa
     4981 gaggaaatcc agcgtgttgt tccagtgatc aaagcgattc gcaaggaaag tgatgtactc
     5041 atttctatcg atacttggaa aagtcaggtg gcagaggctg ctttggctgc tggtgccaat
     5101 ctagttaatg atatcactgg tctcatgggc gatgaaaaaa tggctcatgt ggttgctaaa
     5161 gctggagcga aagtagtcat catgtttaat ccagtcatgg ctcgacctca acaccctagc
     5221 tcgctcatat tccctcattt tggatttaat caaactttta cagtagaaga gttagctgac
     5281 tttgaaacat tgccaatcga agacttgatg gtggctttct ttgaacgagc actagcgaga
     5341 gcggcagaag ctggtattgc accagaaaat atcctgttgg atccaggaat tggctttggt
     5401 ctgaccaaga aagaaaatct cctcctttta cgggacctgg ataaactaca tcagaagggc
     5461 tatccaatct ttctcggagt gtcgcgcaag cgatttgtca tcaatatcct agaggagaat
     5521 ggttttgaag tcaatcctga gacagagctt ggtttccgaa atcgggacac ggcttcggct
     5581 catgtaacta gtatcgctgc gagacagggt gtagaagtgg tgcgcgtgca tgacgtagct
     5641 agtcacagga tggcagttga aattgcctct gccattcgtc tggctgatga agcggaaaat
     5701 ttagatttaa aacaatataa ataagatgaa agaaattgaa aacaatcagt ggattgctaa
     5761 ctaccggacg gatcaaccgc attttggctt ggaacgaatg gtggaactgt tagctttgcg
     5821 tggcaatccc catctcaaac tcaaggtcct ccatatcgga gggactaacg gcaagggatc
     5881 gactattgct tttttgaaaa agatgctaga aaagctaggg ctgagagttg gcgtgtttag
     5941 ctcgccctat ctcattcatt acacagacca gattagcatc aatggggaat cgatctcaga
     6001 agcgaggcta gaagctctca tggcagacta tcagtctttg ctggagggag aagcggtcgc
     6061 caatttacag ggcacaaccg agtttgagat tatcacagcc ctggcctatg actactttgc
     6121 ctcagagcaa gtagatgtgg ccatcatgga agttggcatg ggtggacttt ttgatagtac
     6181 caatgtctgt cagcccattt tgacaggaat tacaactatt ggcttggatc atgtggcctt
     6241 acttggtgac accttggagg ccatagcaga gcagaaggca ggtattatca aacaagggat
     6301 gcccttggta acagggcgta ttgctccaga agccttggct gtgattgacc gcattgcgga
     6361 agggaaagat gcgccgagac ttgcctacgg gacagattat caggttcgtc atcaagacag
     6421 tgtggtgaca ggggaagtct ttgactatac aagtgctgtc agacaaggtc gcttccagac
     6481 tagcctgctt ggtttgtacc aaatagagaa tgctgggatg gccatagctt tacttgatac
     6541 tttttgtcaa gaagatggtc gagagctagc aagcaatgac tttcttggtc aagccttgga
     6601 agaaacaagt tggccagggc gtttggaaat cgtgtcaaga gatcccttga tgattttgga
     6661 tggagcccat aatccccatg ctatcaaggc cttgttggta accttgcaag aacgttttgc
     6721 ggattatcat aaggaaatcc tcttcacttg tatcaaaacc aaagccttgg aggatatgtt
     6781 ggacttgctg ggagccatgc cagataccga gcttactcta acacattttg cggatagtcg
     6841 ggcgacggat gaaagcgtgc tgaaagaggc agctaagtct agaaatctca gctaccaaga
     6901 ttggcatgat tttctagagc agaatgtgac agataaaaaa gaagagaaac aaacagttag
     6961 gattgtcaca ggttccttgt atttcttgag ccaagtgagg gtctatctga tggagaggaa
     7021 gaacgagaat ggatacacaa aagattgaag cagctgtaaa aatgattatc gaggctgtag
     7081 gagaggacgc taatcgcgag ggtttgcagg aaacacctgc tcgtgtagcc cgtatgtatc
     7141 aagagatttt ttcaggtctt ggtcaaacag cagaggaaca tttgtcaaaa tcctttgaaa
     7201 ttattgacga taatatggtg gtagaaaagg atatcttttt ccataccatg tgtgaacacc
     7261 acttcttgcc attttatggt agagcgcaca ttgcctacat tccagatggt cgtgtggcag
     7321 gcttgtctaa gctagcccgt acggttgaag tttattcgaa aaaaccacaa attcaagaac
     7381 gtttgaatat cgaagtggcc gatgccttga tggactatct aggtgctaaa ggagcctttg
     7441 ttatcattga ggcggaacat atgtgtatga gtatgcgtgg tgttagaaaa ccaggcactg
     7501 caaccttgac gacagtagct cgtggtctat ttgaaacaga taaggacctc cgcgaccaag
     7561 cttatcgttt aatggggcta taaaaagaat ccgtttcaag cggatttttc tagaaaggaa
     7621 tcattatgga tcaactgcag attaaggatt tggaaatgtt tgcctatcat ggtctttttc
     7681 ctagtgagaa agaattgggg cagaaatttg tcgtttcagc catcctatcc tatgatatga
     7741 ccaaggcagc tacagacttg gatttaacag cctctgtcca ttacggagaa ttgtgtcagc
     7801 agtggacgac ttggtttcag gaaacgagtg aagatttgat tgaaacggta gcctataaac
     7861 tggtggaacg tacctttgag ttttatcctc ttgtccaaga aatgaagttg gaactgaaaa
     7921 aaccttgggc accggtgcat ttgtcactag atacttgctc ggtaaccatt catcgccgca
     7981 agcaacgagc ctttatcgcc ttaggaagca atatgggaga taaacaagca aacttgaagc
     8041 aagccattga caaactgcga gctcgtggca tccatattct caaagagtcc agtgtcttag
     8101 cgacggagcc ttggggtgga gtggagcagg atagctttgc caatcaagtg gttgaggtgg
     8161 aaacctggct accagcacaa gacttgttag aaaccttgtt agccattgag tcagagctgg
     8221 gacgggtgag agaagtgcat tggggacctc gtttgattga tttggacttg ctctttgtgg
     8281 aggaccagat cctttataca gacgacctca tattgcctca tccttacata gcggaacgcc
     8341 tttttgtcct tgagtcctta caggaaattg cgcctcattt tatccatccg atattaaaac
     8401 aaccgatccg caacttgtat gatgctttga aaaaatagaa aaactctagt tttcagtcac
     8461 ttgcaactga aggctagagt ttttaaaata ggtcattttc ttctgggagg aggatagttt
     8521 ctctaccgtc catgtctaaa accagtactc ttgggggata acgagggtcg aaaggatggt
     8581 taaagtcaaa atcaatggct gtagggaggt gttgacttga aaagtggaag gtaatctttc
     8641 cttggttatt aagcaattga aactcgagtt cttcttccaa ttcaaagaca ttttttaaga
     8701 aatggtcgat gatataccaa aaagagtcaa tgatgtcatc aggcaagctg gtaacaatgc
     8761 caaaactagc agaccgcatg tgggtattgg taaaagccat atatctgtcc cctttctttt
     8821 cccttatcat acagcaaata ggattaaaaa tcaagaaaag gtgatttttt gaaaaggatt
     8881 ttagttacag ggagaaatag ggaaaaattc ccaaaaatct accgaagtta ataggtaact
     8941 tcccaaatta acttgattat ataactttca gttattttga gaagttaccg aaaaatattt
     9001 ttcatatcta ttgactttta ggggtgaaat ttggtatgat agtaggcggt attgtttacc
     9061 ccatttgaaa ggccccggaa ccttccaaat acttttcgat gggaaggaac acccatcacc
     9121 gtaaacaaaa atcgaactat atataggaga aatcatgaac aaaacaacat ttatggctaa
     9181 accaggccaa gttgaacgta aatggtacgt agttgacgca actgatgtac cacttggacg
     9241 tctttctgca gtagttgcta gcgtacttcg cggaaaaaac aaaccaacat ttacaccaca
     9301 cactgataca ggtgacttcg tgattgttat caatgctgaa aaagttaaat tgactggtaa
     9361 aaaagcaact gataaaatct actacactca ctcaaaccac ccaggtggat tgaaacaaat
     9421 ctctgcaggt gaacttcgtt ctaaaaatgc agtacgtttg attgagaaat cagttaaagg
     9481 tatgcttcca cacaatacac ttggacgcgc tcaaggtatg aagttgaaag tatttgttgg
     9541 agctgagcac actcacgctg cacaacaacc agaagttctt gacatttcag gacttatcta
     9601 aggaaaggaa caataaagta tgtcacaagc acaatatgca ggtactggac gtcgtaaaaa
     9661 cgctgttgca cgcgttcgcc ttgttccagg aactggtaaa atcactgtta acaaaaaaga
     9721 tgttgaagag tacatcccac acgctgacct tcgtcttgtc atcaaccaac cattcgcagt
     9781 tacttcaact gtaggttcat acgacgtttt cgttaacgtt gtaggtggtg gatacgctgg
     9841 tcaatcagga gctatccgtc atggtatcgc tcgtgccctt cttcaagtag acccagactt
     9901 ccgcgattca ttgaaacgcg caggacttct tacacgtgac tcacgtaaag ttgaacgtaa
     9961 gaaaccaggt cttaagaaag ctcgtaaagc atcacaattt agtaaacgtt aattcgaaag
    10021 aattactata cttatacaga gcacctttcg gggtgttctt tttttatact ttcttactaa
    10081 attggtgcaa ttgacacagt tgttgcgact ttagtcgctt acaaatgtgg ctgcaacctg
    10141 acaaggtcag ttgcctcaaa acgttaatca atacgattat atcaacgttt caaagcactc
    10201 aaaagtttac cttatgggtg cttttgtctt gttcttgttt caattgacta taaatcgcta
    10261 taagaaaaaa tcattttatt ggtataaaga agtgattgaa agtaatggcg aaacgttaga
    10321 taattagttc ataaaaaaca agtttagatc ctcatctaaa cttgtttttt aaaaattgaa
    10381 ggatgatttt ggaggatata agatgacatt gactattcat gtatattata aaggtgatgg
    10441 agatagtgca ataaagtttg caagagaaat gcttgatagt ggccttgttg aagaaattag
    10501 aaatcaaaaa ggtaacttga aatacgaata ttttttacca attgaaaaag agggaactat
    10561 tctccttatt gatcagtgga taaatcaaga agctttagat aagcatcatc aatcaaagac
    10621 aatgcagaaa atcttagatt taagaaaaaa atatcacttg cagatgcaag ttgaacgtta
    10681 tatagaagat gattctggga tgccagaaag cgataagtcg tttatagaca cagggaatta
    10741 gaattattgt gagagttttt gtagtttgaa agtattgaaa atcgtaaaga tatcattacg
    10801 agaatacaag aagatattgt tctatttcca ttaaaaatta cttctttcct taacaataag
    10861 gaaaaagaat gcgttttcat cttttggttt gaggtttata ataagagtat caaagtcagg
    10921 aggaaaaaag atgactactt ttaaagatag atttttatgg ggtggtgctg ttgctgctca
    10981 tcaacttgaa ggtggatggc aagaaggtgg caagggaatt agtgttgctg atgttatgac
    11041 tgctggtcgt catggagtag ctcgtgaaat tactttggga gttttagagg gtaaatatta
    11101 tccaaatcat gaggcgatag atttttatca tcgttataaa gaagatatag cactttttgc
    11161 tgaaatggga ttcaagtgct tccgtacctc tcttgcatgg acacgtatct ttccaaaagg
    11221 tgatgagtta gagccgaatg aagaaggatt acagttttat gataatcttt ttgatgaatg
    11281 cttaaagaat ggtattgaac ctgtcatcac tctatctcat tttgaaatgc cttatcactt
    11341 agtgaccgaa tatggtggtt ggaaaaatag gaaattgatt gatttctttg ctcgttttgc
    11401 agaagtcgta tttaaacgtt acaaagataa ggttaaatat tggatgactt tcaatgaaat
    11461 caataatcaa gcgaattatc aggaagattt tgcaccattt actaactcag gtattgtata
    11521 tgaggaaggt gataatagag aggcaattat gtatcaagca gtacattacg aattagttgc
    11581 ttctgcacga gctgtaaaaa ttggtcatga gattaatcca gattttcaaa taggttgtat
    11641 gattgcgatg tgtccaattt atccagctac ttgcaatcct aaggatatct taatggcaat
    11701 gaaagctatg cagaagcgtt attattttgc tgatgtgcat gttttaggta aatatcctga
    11761 gcatattttc aagtattggg aacgaaaagg tatttcagtt gattttactg cccaggataa
    11821 agaagattta cttggtggga ctgtagatta cattggtttc agttactata tgtcctttgc
    11881 tatcgactct catcgtgaaa ataatcctta ttttgattat cttgaaacag aagatttagt
    11941 gaaaaataat tatgttaagg cttctgaatg ggagtggcaa attgatccag aaggtttacg
    12001 ttatgcgtta aattggttta cagaccacta tcacttacca ctctttattg ttgaaaatgg
    12061 ttttggagct atagatcaag ttgcagcaga tggtatggta catgatgatt atagaattga
    12121 atatctaggt gcccatattc gtgaaatgaa aaaggctgta gttgaagatg gtgttgattt
    12181 aatgggttat actccatggg gatgtattga tttggtttca gctggtaccg gtgaaatgcg
    12241 gaaacgttat ggctttattt atgtagataa agatgacaat gggaagggaa gttataatcg
    12301 ttccccgaaa aaatcttttg gctggtataa ggaagttatt tcatctaacg gtgaatcagt
    12361 agaatagtat aaacaaactg agattattct cagtttgttt agcatattga ggtgacatat
    12421 gattggaagt attgcagcaa ttttaacaac atttgcattt ttaccacaag tttttcgtgt
    12481 agttaagaca aaggacacag gaactattgc tctaggtatg tatgttatgc aagttattgg
    12541 tattgcattg tggcttgctc atggtattcg tataggagac ttgcctttga ttttagcaaa
    12601 tagtgtttca tttctactct caggaataat tttattttat aaattgaagt ataaataatt
    12661 tttttccata tcatttagga aaatgaggga attgtcattg gaaacgcttt attttataat
    12721 aaaaatagat aacaaataag ccaacttagc acagctttga ttggatttaa gaaaaggaga
    12781 aaatattatg gcaaaagctt taattatttg tgcagcagga atgtcttcat cacttatggc
    12841 acagaaaaca acagagtttc taaaaggaaa agggaaagat attgtagttg atgctattag
    12901 tgctactgaa ggagggaaag ctatcgcagc agcagctttt gatttgtatc ttgtcagccc
    12961 tcaaacaaaa atgtacttta agcaatttga agaggctggt tctaaagcag gaaaaccagt
    13021 tgtacaaata cctcctcaag catatattcc tattccaatg ggaattgaaa aaatggctaa
    13081 tttgattctt gagaatattt gatgaacaca tgaaatgtca ataaatattt aggttaagat
    13141 aaattgtttt gagtttgata taaactgatt taagtgtata atatgcttca atatatgaaa
    13201 acatacgttt taggagggaa tgaatgtgtt aaacattaaa gagaaagata tccttcaatt
    13261 tttaataaaa aataaggaac gttttgttac aagcaaagaa ctggcagaat atttatcctg
    13321 ttcagataga actgtccgta atgtactgaa attaattgag aagacaatga ttattcaagg
    13381 agtccggttg atttcaaaac aaggtcaagg gtatcaaata ttttttgaga atcaaggcgc
    13441 ttaccaggag tttagacaaa cttatgaact ggaagaagac tatacgaaaa ctgcggtttc
    13501 aaaaggtgat gatcgtttag tatttatctt aaataaatta ttatttgagc aagttccagt
    13561 tctttttgat gatttagctg atgaacttta cgttagccgt tcaacattat ctcatgattt
    13621 cagaaagata cgagtgatgt tatcagagta taatttgtcc attgagagta gggcgaataa
    13681 aggagtttat gtctcaggcg aggaacgtga taaacgacgt tttatcataa attatttcct
    13741 agagaatcaa ttttttaaaa caatacattg ctatgtaaaa tttaactttt ttgatcaaac
    13801 tgttccatta gaagaatttg ctagaattgt tttggatgaa tgccaagagg ccaacctaaa
    13861 actatctgat tttgtactac agaatttagt agttcacata gcattgtctg tgattcgttt
    13921 aaaattcgga tttgaaataa aaaatataga ctgtcagatg actgatgatg caatagagag
    13981 aaaggttgcc caaagaattc tttctaaagt aagagaagta acaaatcagg aatttccagt
    14041 tcaggaaata gactacatta ctttgcattt gttagctaag agtcaacaat gtcaaaaaaa
    14101 tcagaagaat atttctgaag aagttttaaa aaaatcttta tttaaaacat ttcagaattt
    14161 aggattagat gatatgtata acttttcttc agatttccaa ctaattgaag gattgataac
    14221 tcatctaatg acactacaag tacgtttaga aagccggatt accttaaata accctttggt
    14281 agatgaaatt aaacagaatt atagtgatat attctttatg actagagaaa ttcttgcaaa
    14341 tatggacaag ttcttggagt ggacaatatc agatgatgaa gtagcatatg taagtcttca
    14401 ctttttagct gctatggaac gtagcaaaga gagtactaag tttaatattc ttgctatttg
    14461 tgcaacagga tttggtgcag cccaaatgtt aagaaatcgt ttggaaacgg agtttgggaa
    14521 gcgagtagaa gttgttgatg taataggcta ttatgaattg aatcaagaaa aacttaaagg
    14581 aatagatttt atagtgtcag ctgttgattt atcaaatcta tattttcaaa tcccagtttt
    14641 taaagttagt gtgtttctta agagtgatga gatggaaatg attagaaaag ctatggttca
    14701 gatgcaagtt tctagttatg tacaatcatc aaagattaac aaatttgaaa acaacggctt
    14761 tagacagtat tttagtaaag aaaacttttt aatatgtact gaatcagaca aggtaaattt
    14821 acttgaaaag atggttgaga gtttatctgt tggtgaatca aatgagtttg aacaatcttt
    14881 actttatgga attaaacagc gcgaagaatt aagttcagtt gttttttctg aaaaaattgc
    14941 agttccgcat cctattcagc cctttggtac agaggaaaag gtttcggttg caatttgtaa
    15001 agattcgtta ctctgggata atcaaagttc acatgtccag ctagtatttc ttctatctcc
    15061 atcaatatat gggaacgaag gtttggcaac tgtgactaaa aagatagtct ctctgacaga
    15121 gaatgatgaa ttgcaaaatc agctaatatc ttgcaataac tttgaagatt ttattaacat
    15181 atttgagaag ataaaatagg aggttcatat gaatcaagag gaactgcagg ttgcagcatt
    15241 tgaaattatc ctgcattcgg gaaatgcaag gtcagaaata catgaagcat ttgcaaaaat
    15301 gagagaaggt agttttgatg atgcagaaag taaattaaat caatcaaatg agataattct
    15361 tgaagcgcat catgcacaaa ccaaactctt gcaagaatac gcaagtggag tggaaattaa
    15421 aattgaaatt atcatggtac atgctcaaga tcatttaatg accactatga cattattaga
    15481 agtagcaaag gaaatgttag ctctttataa gaaagttaac taaatatgtg ttgttatata
    15541 aggaggaaat gatatggata aaaaagaacg acaaaagatt gaacaacaac gtcgagagat
    15601 ggctctaact aatacttttt ttaatcgata tcttcttcta cgttattcaa tagcactctt
    15661 cttttttggg aatatttatt ggcttttgaa tcagtttatt aatccctcgc ctattattat
    15721 tttccccatt atgctcatag tattttctat tttagcaact attgaacaat ttaaacttta
    15781 tggaaatagg aaagaaaagt tgggaataac actaatgttt gttagaatac aaatgcttat
    15841 ttcaatagga ttacttgttt taacttggac aagttggttt aagaatcttt ttccgatttt
    15901 tgaaaataac caagtagcac gtttatttgt ttttgtagtt cttctattag gtttagttct
    15961 gagtttgtta gacattagaa gaattaaaaa aatttataaa cgaacagata aggtttatca
    16021 acaatttgtc caattggaaa agaactcact tagtttataa tcctgatcta gtataatttg
    16081 tatttgaaac tagtctttag aaagtaaaaa ttattatgtt ttattaagga ggtctattta
    16141 tggatcaaca aaacgggttg tttggttttc ttgaaaacca tgttatggga ccaatgggca
    16201 aacttgctca gtttaaagta gtacgtgcta tcacggctgc aggtatggct gctgtaccat
    16261 ttactattgt aggatcaatg tttttggtat tcagtatttt gccacaagct ttctcatttt
    16321 ggccaattgt ggcagatatt ttctctgctt catttgataa attcacatca ctttacatgg
    16381 ttgcaaactc tgcgactatg ggttctctat ctctttattt cgttctatca cttgcatatg
    16441 aattgacaaa aatttatgca gaggaagaag aactcaatat gaatcctctt aatggtgcct
    16501 tgcttgcctt gatggctttt gtcatgacag taccgcaaat catttttgat ggtggaatga
    16561 tgaagactgt gacaagtcta aaagaaggtg cagtaattgc agatggatgg gcaatgggaa
    16621 atggagtcgc acgttttggg acaacaggga tttttaccgc aatcattatg gcaattgtga
    16681 ctgttcttat ttatcgtatg tgtgttaaac ataattgggt tattaaaatg cctgaagctg
    16741 ttccagaagg agtttctcgt ggatttaccg ctttggttcc gggatttgtt gttgcatttg
    16801 ttgttatctt tatcaacggt cttcttgtag caatgggaac agatattttt aaagtcattg
    16861 caattccatt tggttttgta tccaatctga ctaattcgtg gattggttta atgattattt
    16921 atctattgac tcaactactt tggattgtag gtatccacgg tgcgaacatt gtttttgcat
    16981 ttgttagtcc aattgctctt gctaacatgg ctgaaaatgc tgctggcggg cacttcgctg
    17041 ttgcaggtga attttctaat atgtttgtaa ttgcaggtgg ttctggtgca actttaggac
    17101 tatgtttata tattgctttt gcctctaaat ctgaacagct taaagcaata ggacgagcat
    17161 ctgtagttcc ggccttattt aatattaatg aaccattaat ttttggatta cctattatct
    17221 ataatccagc cttagctata ccatttattt tagcaccaat ggttactgct actatttatt
    17281 acgtagcgaa ttctctaaac tttattaagc caattatcgc acaggttcca tggccaactc
    17341 cagtagggat tggagctttc ttagggacag cagatcttcg agctgtatta gttgctctag
    17401 tatgtgcatt tgcagcattc ctagtctatc ttccattcat ccgtgtatat gatcaaaaat
    17461 tggtgaaaga agagcaaggt atctaataag taaaaaagta tactcgatga tagaatccat
    17521 atagtttaaa taatgagcgt taacattagc agtgaagagg tctttttaag atattcttct
    17581 ctgctttttc atattttttc gctatgtagg gtatgaagca aaatagaaag tagttcgaat
    17641 agttgataaa cagggaattg ctgttattta aaaaaaaaca ataaagtaaa gtatgttatc
    17701 gtagaatacg atacaatagt aaaaaagcaa aaagaatgcg ttttatattt gggtttgagg
    17761 tttataaaat aggataagca tgctgaaaac ttagatatga caaacaaaat aaaattttta
    17821 aaagctacat agaaacatgg tataatgtat ctaaaggagg tagcatatgt ccttagatat
    17881 agataaagaa aagatgacaa tcatgggaat agcttttgaa aaccgatccg tttttaggag
    17941 tgtttggtat gctttaagta caaatatgat tgaaggatgg cgacctacgg ttagtgatgt
    18001 tgaaaaatta cgagatgaag ctcttgctct ggggatgact taatgaagcg caactgttat
    18061 gagtcttatg actatgttga tccggataat ttatataccg atccgggttc ttcagttcta
    18121 agaaataagc aggaaggaaa aaagcacgcg agcttgaata tcgtatgatt gctagtaaga
    18181 gtttgaaatt atttatcaat cctatcttag ttaatagttt aaaagtagtt tgtttcacaa
    18241 ctgcataagc ttagaaaagt tgaaaagtga taactcttta ataaactctt ggtttgttaa
    18301 aagatatttt gtccactaca ttttttcaat tgactattat ttgtcataga tataacagat
    18361 agaacattgc attcagaata atgaaaaacg catcaaaaat ggtgcgttct gtttttatgc
    18421 taccataaaa ggaggaaaac aaattgaaaa tttttaaggg agagttttat cgaatctctg
    18481 tattaacaga caagctagta aggttagaat actctcgaac tggaaatttt gaggatagaa
    18541 cgacacaact tatctataat agagattttg gccaagtttc gttagattat atcgagacat
    18601 caaatgtact agatattatg acggactatt ttcatctgca ctttaataaa ggagaattta
    18661 acgccgaaaa tttatttata gaattaaaag gaaattttgc cgtatatggt agtcgctggt
    18721 attttggtga atctattgaa acgttaaaag gaacagctcg gactctggat aaggcagatg
    18781 gagcaatctc gttagaagat ggaattatta gccgaaatgg tatagcctta ttggatgatt
    18841 ctcaaggatt tatttgggat gaacaatctg gttatattga gagagaaaat caaattgacc
    18901 tgtatttctt tgcctatggg catgattata gaggagcaat cagagacttt taccatttga
    18961 ctggttcaac acccttgttg ccaagatatg ctttaggcaa ttggtggagt agatattggc
    19021 cttatacgtc ggatgaatac ttggatttaa tagacagatt tgaaacagag aaaattccat
    19081 tatctatcgg tgtgttagat atggattggc atataactga cattccagct cgttttggaa
    19141 gtggctggac aggatatagt tggaatagaa acttaatacc aaatccagaa cagttattgc
    19201 aacaacttca tgatagaaag ttaaaactct ccttaaatgt ccatcctgct gatgggatac
    19261 gggcttatga agaagcttat cctcaaatcg caaaacggtt ggggttaaat gtagaactag
    19321 aagaacctgc tatttttgat ttttttaatc cctcttttag ggaagcctac tttaaagatg
    19381 ttcattatga gctagaaaag cagggagtag atttttggtg gattgactgg caacaaggga
    19441 cacaaggtat gctagattca ctttggcttt taaaccatta tcactatcag gatagttgta
    19501 aaaatgcaga aggtggtttg actttatcaa gatatgcagg tcctggtagt caccgctacc
    19561 ctgttggttt ttcaggggat actattatta gttggaattc cttaagattt caaccctatt
    19621 ttacagcgac agcatctaat atcggttata gttggtggag tcatgatatc ggtggacata
    19681 tgttggggga ttatgacgaa gagctacaaa ctagatggct acagtttggt gtttttagtc
    19741 cgattactcg attacatagt tctagaagtc cttttaatag taaagaacct tggttttttt
    19801 cagaaacaac atctaagatt atgaagaaat accttcgttt gagacatcag atgattccct
    19861 atctatatac catgaatgta cagacacatg aggaaggtgc cccattaatc agtccaatct
    19921 attatttcta tccagagaat gatgagagct ataatgttcc aaaccaatac ttttttggaa
    19981 cagaactgat ggtggctccc attgtagaaa agatggattt gacattccaa tctgcaaaag
    20041 tagatgtatg gttccctgaa ggtgaatggt atgacttctt ttcagagaaa aaatacacag
    20101 gtggtgtgaa gttaagtgtt tatagggacg tttcgaatat tcctgtgttt gcaaaaagtg
    20161 gtgcaatcat tcccttggtt ggttctgaga taggtatggg tgttgattta cctgaggttg
    20221 tagattggta tgtattccca ggcaaacaac attcttttga aatgcttgaa gatcaaaatg
    20281 gtcaaagata taaaacaaga ttatcaatcg attgggaaat gggaatggta gagttagcat
    20341 tacaaggaga ttctagtatc gttccaagca atagaaaaca tagaattcat tttaaaggaa
    20401 cgaatgtgtc tataattgaa ttgccaaata agaatgatac agctaaattt gaatggaaag
    20461 ataataaaag gacatcttta aatgacgaag tttttagact actaaagaca gcttctcttc
    20521 catatgaatt aaaagataga ttgttaaatc aattcatcaa tgcgaaaaac tctcatgact
    20581 taatgaatat cttgcatcat caggataagg aattgagagg gcgtttgttg gaaatgatat
    20641 ttactagcca aaactaattg atataattag aaagtcattt gtttagtgta tatgaagatt
    20701 ctgtatggta ttcgttatca ctggtcacat tgaaaatgtg aaataagcac ctacaacata
    20761 gactttacaa cacttcatgt ttcatatcat ggggtgtttt tctatttaag tcaaagccaa
    20821 tcaaaaaatt tcactattca tcaggttaaa ggaaacctaa tcatagtgag attgtgaatt
    20881 atagtagagt ttgtatcgcc tcttcaattt gttttgggtc tgtttttgaa gaaaagcgtt
    20941 caaagacttg cccatcacga ccaatgagaa acttagcgaa attccattcg attcgttttc
    21001 ctagtgggcc agatttatgg tcttttaacc agacatagag agggtctgct tccttaccgt
    21061 tgaccttaat cttggcaaaa cgtgggaagg tggtttgaaa atgtaggcta cagaaggcgt
    21121 tgatttcctc tgcgctgccg ggtgcttgtc ccataaactg attgcaaggg aaatccaata
    21181 tttcgaagcc ctgatcttga tagcgttcat agagttcttg aagtccctgg tactggggcg
    21241 ttaaaccaca tccagtagca gtgttgacaa tcaagagaac tttgccacga tagctatcca
    21301 agggagttgc ttggttgttt tggttcaaaa cggaaaaatc ataaagtgaa gtcatgaggg
    21361 cctcttttct ttttctacat tgtaacagtt tttacttttt tcgtcgagtc ggatggaaga
    21421 tattgttgaa gaataagcct tcaatatgat agaaatcgtt tacaaataac tttaaaaatg
    21481 gtatgattta attaaaccgg tttactttgt tgctataaat ctctaatttg agatttagtt
    21541 cctattgatt ttacaatatg tttattggag tgtatacatg caaacaaaaa caaagaagct
    21601 cattgtgagt ttgtcttcac ttgttttatc aggattttta ttaaaccatt atatgacagt
    21661 tggagcggaa gaaacgacta cgaataccat tcagcaaagc cagaaggaag ttcagtatca
    21721 gcaaagggat acaaaaaatt tagttgaaaa tggtgatttt ggtcagacgg aggacggaag
    21781 cagtccgtgg acaggaagca aagctcaggg gtggtcagct tgggtagacc agaagaatag
    21841 ttctgcagat gcctcaactc gagtcattga ggctaagggt ggggctatca ctatctcaag
    21901 ccatgagaaa ttaagggcag cggttcaccg tatggttcct attgaagcta agaaatagta
    21961 taaactgcgt ttcaagatta aaacagataa taaagtcggg attgccaagg ttcgtatcat
    22021 tgaggaaagt ggtaaggaca agcgattgtg gaattctgca acgacgtcag gaacaaagga
    22081 ctggcagacc attgaagcag actatagccc gactttagat gttgataaaa tcaagctgga
    22141 gttattctat gaaacaggaa ctgggactgt ttcctttaag gatattgagc tggtagaggt
    22201 agcagaccag ccttctgagg attctcaaac agataaacag cttgaggaaa agattgattt
    22261 accaattgga aaaaaacatg ttttttctct tgcggactat acttataagg tagaaagtcc
    22321 tgacgttgct tcagtcaaaa atggaatttt agaacctctt aaggaaggga caaccaatgt
    22381 cattgtcagt aaagatggca aggaagtgaa aaagattcct ttgaagattc tagcctctgt
    22441 taaggatgca tacacagacc gtttggatga ctggaatggc atcatcgctg ggaatcaata
    22501 ctatgattct aaaaatgaac agatggccaa attaaaccag gaattggaag gaaaggtagc
    22561 tgatagccta tctagtattt caagtcaggc ggaccgcacc tatttgtggg aaaaattttc
    22621 aaattataaa atgtctgcaa atctgactgc cacttatcgg aaattggagg agatggccaa
    22681 gcaagtgacc aatccttctt ctcgttatta tcaagatgaa actgtcgttc gaacagtcag
    22741 ggattccatg gaatggatgc ataaacatgt ctacaatagt gaaaagagca ttgttgggaa
    22801 ctggtgggat tatgaaatcg gtacacctcg tgccatcaac aataccttgt ctctgatgaa
    22861 agaatacttc tctgatgagg aaattaaaaa atatacagat gtgattgaaa aatttgtacc
    22921 agatcccgaa catttccgaa agacgactga taacccattc aaggctctag gtggaaactt
    22981 agttgatatg ggaagggtaa aagtaatagc tggtttactg cgtaaggatg atcaagaaat
    23041 ttcttctacc attcgctcga ttgagcaagt gttcaagttg gtagagcaag gtgaaggttt
    23101 ttatcaagat ggatcctata tcgaccacac caatgttgcc tatacgggtg cttatgggaa
    23161 tgttttgatt gatggcctgt ctcaactgtt gccagtcatt caaaagacca agaatccaat
    23221 cgataaagat aaaatgcaaa ccatgtacca ctggattgat aaatcgtttg ctcctttgct
    23281 ggtgaatgga gagctgatgg atatgagtcg tggacgctcg atcagtcgtg caaatagcga
    23341 ggggcacgtg gccgcagtag aagtactaag agggattcac cgaatagcgg atatgtctga
    23401 aggagaaacc aaacaacgtt tgcagagtct tgtgaagacc attgttcaat cggatagtta
    23461 ttatgatgtc tttaagaatt tgaagactta taaggatatc agtttgatgc aatccttgtt
    23521 aagtgatgca ggagtcgcaa gtgttccaag aacaagttac ctatctgcct ttaacaagat
    23581 ggataaaaca gccatgtaca atgcagagaa agggtttgga tttggcttgt cactcttttc
    23641 cagtcgtacc ttgaattacg aacacatgaa caaggaaaat aaacgtggtt ggtatacgag
    23701 tgatgggatg ttctatcttt acaatggcga tttgagtcac tatagcgatg gctactggcc
    23761 aacagttaat ccatataaga tgcctggtac aacagagacg gatgctaaga gagcggatag
    23821 cgatacaggt aaagttttac cgtctgcttt cgttggaacg agcaaactag atgatgccaa
    23881 tgcgacagca accatggatt tcaccaactg gaatcaaaca ttgactgctc ataagagctg
    23941 gtttatgcta aaggataaga ttgccttttt aggaagcaat atccaaaaca cttcaacaga
    24001 tactgctgca actacaatcg accagagaaa actggaatca agtaatccat ataaagtcta
    24061 tgtcaatgat aaagaagcct cccttacaga acaagaaaag gattatcctg aaacccaaag
    24121 tgtcttttta gaatcgtccg attcgaaaaa gaatattggt tactttttct ttaagaagag
    24181 ttcaatcagt atgagtaagg ctttgcaaaa gggagcctgg aaggatatca atgaaggaca
    24241 gtcagacaag gaagttgaaa atgaatttct tacgattagt caggctcata agcaaaatgg
    24301 agattcttat ggctatatgc tcattcctaa cgtgggtcgt gccaccttca atcaaatgat
    24361 aaaagagtta gaaagtagcc tcatcgaaaa taacgaaacc cttcagtctg tttatgatgc
    24421 caaacaagga gtttggggca ttgtgaaata tgatgattct gtctctacta tttccaacca
    24481 attccaagtt ttgaaacgtg gagtctatac cattcgaaaa gaaggggatg aatataagat
    24541 tgcctactat aatcctgaaa cccaggaatc agctccagat caggaagtct ttaaaaagct
    24601 agagcaagca gctcagccac aagtacagaa ttcaaaagaa aaggaaaaat ctgaagagga
    24661 aaagaaccat tcggatcaaa agaatctccc tcagacagga gaaggtcagt caatcttggc
    24721 aagtctaggg ttcttgctac ttggggcgtt ttatttattc cgtagaggaa agaacaacta
    24781 atttgttcat catctagatg aattacatga aactgtggaa aatagaaaaa atccgaagaa
    24841 ggccaaatat cttcggattt ttcttttaaa aagggataag ttgatactta tcctttttta
    24901 cttcattatg tgactatagc gttttgaaac tagaatagga cgtcataact actaaaagat
    24961 ttctataaat tcatttgatt ttcctaatca atttgttcgt atcctatttc actccactat
    25021 attagtccgt ctcgctccgt gaggtgcgag acaaaacaac cacccgctat gcgggtgcgc
    25081 gtcgaagatt ataccaaaaa aactccaaac gcgatacaat aaaggtgttc aatccaattg
    25141 taaagcgaaa ggagaaaaaa tatggcacaa aagactcata gtttatcata cacaaagtgg
    25201 atgtgttcta tcatattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat
    25261 atagaagtag tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga
    25321 tcgagggtca cttaatgcca gaccatgtac acatgttagt cagtattcca ctaaggctaa
    25381 gtgtttcaag ttttatgggt tatttaaaag gcaaaagtgc actcatgatg tttgacaaac
    25441 acgccaatct caagtacaag tttgggaatc ggcatttttg ggcggaaggt tattatgtaa
    25501 gtacagtagg gcttaataaa gccacaatta agaaatatag tcaagattaa agaaattatc
    25561 cagtggatga tttcttcacg agtatgaaaa tttgagaacg agtaaagcat gatatatagt
    25621 aaaatgaaat aagaatagga caaaatcgat caggacagtc aaatcgattt ctaacaatgt
    25681 tttagaagca gaggtgtact attccagttt caatctacta tagcactaga taaattgagt
    25741 gtaaaagaat atgaggatcc ctttagggat agtggtaagt aataccaaag tctcttaaag
    25801 aggcaagtga cgagtcaaga gcaataaggc ttgaacaacg tgaaagccag cgtctttagg
    25861 cgctggctga tgatttgggc ttatagctct gagataaacc acccgttaga caggtggtta
    25921 tgattttatc tgagtgtaac atactgttgg gcaatctcgc tgatgcggtc aaagttgcct
    25981 tgggaagcga gtttattgag ttcgccacca attccaacgg cgtctgcacc agcagcgaac
    26041 cattgaggga tgttgtttag accgactcct ccggttacca ttacggaaac ttgtgggatc
    26101 ggtgccttga ctgcagagat atatgctgga ctgagagtac tacttgggaa gagtttgatg
    26161 atttcactac cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg
    26221 tacggtgtgc tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca
    26281 acgtaatttg ctccggctag aatggcatct ctagcagtta cggcatcaag cacagtacct
    26341 gcaccgatac aaacactctt atcgtcctga tacaagtcta caagttcctt gatgatttgt
    26401 cctgcatact gattggtata ggcgatttca atagctttga taccgccctt gatacaagca
    26461 atcgaggctt gcagtccttc ttcctttgta tttccccgaa tgacagcgac aattttctgt
    26521 ttttttagtt caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct
    26581 tgtgcatttg ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga
    26641 agagtgcatt tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa
    26701 tgatggagta gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga
    26761 tagactgcag tttttagttg gacagactct tcaaatagtt cttccagagc ataggcttga
    26821 tagacatttt tgtcttgctc atcactagag cggagggtat ggaaaatggc cttgaaacca
    26881 taggcttctt ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt
    26941 ggaaacatct ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca
    27001 gtaaaacgtg caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt
    27061 ctcagattga gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg
    27121 agaaggatcg tacggacctc ttgaccgata gctacggtga ttccactaaa atgaaaatgg
    27181 ctaatcccct gaaagagaga atccatatct agcatgtttg gctgaatctg gctgatactc
    27241 gtatgcttac gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag
    27301 tagaggccga ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc
    27361 aagaatgtga gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt
    27421 gagataccca gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc
    27481 gaactggcaa catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt
    27541 tcgccaaaca gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac
    27601 ttggctaata cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag
    27661 tattcttgga agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta
    27721 aggatggtca tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg
    27781 cgttgttcag ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag
    27841 cgttcaaaca tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg
    27901 atagacaagg cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact
    27961 gctagaccac agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta
    28021 ccacagccgg taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt
    28081 ccgttctgca cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat
    28141 aattggtagc cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg
    28201 ctagcttgac tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac
    28261 tcaggttgtt ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg
    28321 acaaaattgc tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt
    28381 ccccaacgtg cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca
    28441 tcttcttgca attcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt
    28501 ccgttacatt ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc
    28561 aagccccctt tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc
    28621 gaacaaatat tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt
    28681 gaaacgataa atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc
    28741 atttcgcaca ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca
    28801 ccaacctctt gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca
    28861 cagacatatc catgggcttc gatgccaact tcacgataag cttcaatccc tttattgacc
    28921 agatcttgat tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca
    28981 atagcaaatc caattccata agaagcgccg gtgatgagag caatttttcc ttttaaagaa
    29041 aactgctcaa ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga
    29101 cttctctat
//
LOCUS       DAVKAU010000021        28436 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVKAU010000021 DAVKAU010000000
VERSION     DAVKAU010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28436)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28436)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28436
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.021"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..376)
                     /locus_tag="VWX48_001109"
     CDS             complement(<1..376)
                     /locus_tag="VWX48_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9171744.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWRGRSAVLNQHIFKVVLDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTK"
     gene            complement(410..1375)
                     /locus_tag="VWX48_001110"
     CDS             complement(410..1375)
                     /locus_tag="VWX48_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9171745.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1493..1906)
                     /locus_tag="VWX48_001111"
     CDS             complement(1493..1906)
                     /locus_tag="VWX48_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU9171746.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1903..2139)
                     /locus_tag="VWX48_001112"
     CDS             complement(1903..2139)
                     /locus_tag="VWX48_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU9171747.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            complement(2199..2600)
                     /locus_tag="VWX48_001113"
     CDS             complement(2199..2600)
                     /locus_tag="VWX48_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9171748.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            complement(2613..4106)
                     /locus_tag="VWX48_001114"
     CDS             complement(2613..4106)
                     /locus_tag="VWX48_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9171749.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            complement(4614..5333)
                     /locus_tag="VWX48_001115"
     CDS             complement(4614..5333)
                     /locus_tag="VWX48_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9171750.1"
                     /translation="MIAKPDNGVGAAATFKLETEDDINHFKQEWDHSTLYFFEKFVTS
                     SEICTFDGLVNKDGKIVFSTTFDYAYTPLDLMIYKMDNSYYVLKDMVPKLRKYGEAIV
                     KEFGMKERFFHIEFFREGDDYITIEYNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGE
                     EFPASEFEPQYCLATSRRANAHYVYSEENLLAKYSQQFKVKKIMPEAFAELQGDYFYM
                     LTTPSRQEMDQMIADFGQRQE"
     gene            complement(5351..5758)
                     /locus_tag="VWX48_001116"
     CDS             complement(5351..5758)
                     /locus_tag="VWX48_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoylphosphate synthase"
                     /protein_id="HEU9171751.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPINRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKQ"
     gene            complement(5816..6511)
                     /locus_tag="VWX48_001117"
     CDS             complement(5816..6511)
                     /locus_tag="VWX48_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9171752.1"
                     /translation="MHIEHLSHWSGHLNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGLVQFFTLSSLDSESWLATWKNAHDQAEMHRAYERYVIEEAIPFI
                     KHKTGWFDGMMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYYNDDAI
                     YQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQKQIPAW
                     FAEWGHDVAHDWE"
     gene            complement(6533..7357)
                     /locus_tag="VWX48_001118"
     CDS             complement(6533..7357)
                     /locus_tag="VWX48_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9171753.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(7494..8708)
                     /gene="thiI"
                     /locus_tag="VWX48_001119"
     CDS             complement(7494..8708)
                     /gene="thiI"
                     /locus_tag="VWX48_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU9171754.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGFVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(8717..9859)
                     /locus_tag="VWX48_001120"
     CDS             complement(8717..9859)
                     /locus_tag="VWX48_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9171755.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            9997..10425
                     /locus_tag="VWX48_001121"
     CDS             9997..10425
                     /locus_tag="VWX48_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171756.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKKDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            complement(10576..12801)
                     /locus_tag="VWX48_001122"
     CDS             complement(10576..12801)
                     /locus_tag="VWX48_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU9171757.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     INENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(12965..14917)
                     /locus_tag="VWX48_001123"
     CDS             complement(12965..14917)
                     /locus_tag="VWX48_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9171758.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIEEMIKSLTGHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALTELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKVIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLAISGDAEVYRAANGAK
                     VATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(14914..15825)
                     /gene="pfkB"
                     /locus_tag="VWX48_001124"
     CDS             complement(14914..15825)
                     /gene="pfkB"
                     /locus_tag="VWX48_001124"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU9171759.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNISNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVKLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(15822..16562)
                     /locus_tag="VWX48_001125"
     CDS             complement(15822..16562)
                     /locus_tag="VWX48_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9171760.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            16724..16811
                     /locus_tag="VWX48_001126"
     tRNA            16724..16811
                     /locus_tag="VWX48_001126"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16758..16760,aa:Ser,seq:gga)
     gene            complement(16981..17328)
                     /gene="ssrA"
                     /locus_tag="VWX48_001127"
     tmRNA           complement(16981..17328)
                     /gene="ssrA"
                     /locus_tag="VWX48_001127"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(17974..19083)
                     /locus_tag="VWX48_001128"
     CDS             complement(17974..19083)
                     /locus_tag="VWX48_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9171761.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            19186..20427
                     /locus_tag="VWX48_001129"
     CDS             19186..20427
                     /locus_tag="VWX48_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU9171762.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEARTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(20658..22070)
                     /gene="sufB"
                     /locus_tag="VWX48_001130"
     CDS             complement(20658..22070)
                     /gene="sufB"
                     /locus_tag="VWX48_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU9171763.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(22124..22564)
                     /locus_tag="VWX48_001131"
     CDS             complement(22124..22564)
                     /locus_tag="VWX48_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU9171764.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(22551..23777)
                     /locus_tag="VWX48_001132"
     CDS             complement(22551..23777)
                     /locus_tag="VWX48_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9171765.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(23788..25050)
                     /gene="sufD"
                     /locus_tag="VWX48_001133"
     CDS             complement(23788..25050)
                     /gene="sufD"
                     /locus_tag="VWX48_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU9171766.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(25078..25848)
                     /gene="sufC"
                     /locus_tag="VWX48_001134"
     CDS             complement(25078..25848)
                     /gene="sufC"
                     /locus_tag="VWX48_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU9171767.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(25998..26192)
                     /locus_tag="VWX48_001135"
     CDS             complement(25998..26192)
                     /locus_tag="VWX48_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU9171768.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(26220..27875)
                     /gene="dnaX"
                     /locus_tag="VWX48_001136"
     CDS             complement(26220..27875)
                     /gene="dnaX"
                     /locus_tag="VWX48_001136"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU9171769.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(27875..28372)
                     /locus_tag="VWX48_001137"
     CDS             complement(27875..28372)
                     /locus_tag="VWX48_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU9171770.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
BASE COUNT         8497 a         6205 c         5153 g         8581 t
ORIGIN      
        1 ttttagttaa atgtttcatt gtggaaccat gagtatgttt tacagcatct tgtaaacctt
       61 tttcaacaac atatttaaaa tacgatttat ctatatctat cttatccaaa accactttaa
      121 aaatgtgctg atttaacact gcggatcttc cacgccactg aaaaacccct aatgtacccg
      181 accacgaaat aagaatatca ccagcttcaa caatgtattt tttatcaatc gtacccgaat
      241 aataatttat ctctgttgaa gttttagtca gattctgtat tctgataatc tctttccctt
      301 cagatgacca atcttgaggt ttaaaagcat agccattgat aaaagtagcc acttcaccta
      361 atttcacttt cttcatgcaa ccacctcctc ggaatatcgg gatttgcttt taagagatga
      421 atttttggtg tgaatgcttg acattatttt gattgaccat ggcataggcc agggttgtgt
      481 caatcttgct atgacctagc agtttttgga cttgttcgat aggcatacct ttatcaattg
      541 ccttagtcgc taaagttctt ctgaacttat gtgggtgaac cttttgtatg ccgagtttgt
      601 ctcctaactt tcttaagcga atctctacac cagcaattcc aagtctctgg gcttttccaa
      661 ctagcgttac aaaaagagca gggtgactat cttttctgtc gttaagataa tttcttaaat
      721 gaattttcgt ccgagcgtca aaatatactg gtctctcctt ctttccttta ccaaagacaa
      781 cacactctct gttttcaaaa tcaatatctg aacgattcaa ctgtacaagc tcccctacac
      841 gcatacctgt cgatgctagt aggtctatta ttgccaaatc tctcaaattt tcacagttat
      901 cacgcataat ttccaaatgt tcatcagtat aagtttcctt cacattttgc tcagtcttaa
      961 ttttctttat ccgtcgaatg ggatttttaa tgatatattc ctcttgctca agccaagcaa
     1021 aaaaagaaga caatatacgc ctaatattgt ctaaatttgc cttactacaa tccttttcag
     1081 actggtaatt tgctaaataa ctccttaaat catctgttgt gagttgtgtc acagactctt
     1141 taatagcatt aaacaagttt tcaatcgtcc tctggtaata acgaattgtt tttgagctac
     1201 agccctctac ctgcttggcg gtaataaata gttgcaacag gttattattc gaatacttct
     1261 gctgcttttt tccgtctact agatgatgtt ctaaactctc tctcaacgct agtaattgtt
     1321 cattatttaa aagaggtaac atttcttgca tgataattgt aacttttgat tccataattt
     1381 ctcactttct tattcatcaa taaaaagaga caatatcagt ttctgcatta cagaattcta
     1441 atattgtctg ttcatttatt ttcttgtgct cattcaaatc cagcatacta ggttactttt
     1501 tgaccttttc tctaacagaa tgttcagaaa cccatttgga gtagcttgtc attttttcat
     1561 cagttaaagc ttctactgcg atggttacac acatttttac tgcttcttct accgttacag
     1621 aaaaacgata gccgtttaat tgtaaaaatt tgaccaaaac gaagaaagca gttcttttat
     1681 tagcattagc aaaaacatgc ttctttatca attggacaaa tagtatcgtt gctttatcaa
     1741 aaattgttgg ataaagagac ttcccaaaga caaattgttc tggtaagttc acaatcatat
     1801 ttaaggcaga agaactaact gtttgaattt tctcatttgg agaataccgt tgaattgcta
     1861 aagcatttat tttttcaatt tgcttttctg tcagatagat tgtcattttt ccaccaaagc
     1921 tttgaaaaca tcgtcgtatt cgtcaaatat tttatctaaa tttaagtcaa aggcatcatc
     1981 agatacataa gaaacctgct gccccaattc ttcaggagta aagataatct caccacttgg
     2041 taacaatttc gcttcgtatt taacaccact tggaatatta aattcacttg gaatcgtaat
     2101 ggtgattgaa tttccttgtt ttcttgtttt tactaccatc tgatttcctc ctttgaagta
     2161 ttataacaaa tcattaccgt aattacaatg gcagaatatc agccaaaata ctcctgcatc
     2221 agagatttct tcaaagtttc aagttcttcc agagattttt ggattgccaa ttgtgattta
     2281 ctttccaaaa agactcccaa gtaatctgat ataatttttt ctttgtatcg ctcattcttt
     2341 tttaagaccg taattgtact accaacagct cccgataatc cataaccaac tgttcctgca
     2401 ttagctccat cccatgctat cagaatatca tctgggagtg cttcagtcat atttaaactt
     2461 tcagtgaatt ttaaattatt attatttctt aaatcatcta tttgaatata acgttggctt
     2521 agagttgttt gttcagcaag tacagtggct ttcttgcctt tttttagaga taagacttcc
     2581 cccaacttca cttttttcat acagccacct ccctacttga gtaatttttc taattcagcc
     2641 aagccagctt gaatttcttt ttctaaatca ttgattttct ttaagatgac ctctgttggt
     2701 tcatactcaa ctttttcata ctcaatctct ttatatttat tgatagacaa atcataatca
     2761 ttttccttta tctcagcaac tggaacaaag aaagattgat ccgttctctg acgttctgct
     2821 tctttttcaa gatgatgaaa gcgttcgata atatctggaa tatcattgtc gctaatcggt
     2881 tgtcgcttat catccaaact taaaccatcc gctttcatat cgtaaaacca gactttgtca
     2941 gtaccaccat taccagtttt tgtaaagatg agaatggcag ttgaaactcc agcataaggc
     3001 ttgaaaacac cactaggcat tgagattaca gcatcaagct tatgattctc tacaatttcc
     3061 tgacgaattc ctttatgagc tttagacgaa ccaaaaagga caccatcagg tacgataact
     3121 gctgctcgtc cacctggttt taaagttcgc aagaaaagag aaagaaagag taattctgtt
     3181 tttttggttt ttacggttgc aagaaggtca ttagaggttg aattgtagtc aagtgagccc
     3241 ttaaaaggag gatttgctaa aaccaaagta tatttatcgg cttcttcatt atcttgagac
     3301 agcgagtcaa ggtaactgat ttgtggattt tctactccat gtagcatcat gttcatcgcc
     3361 ccaagtctca acatagtcgt atccgtatca tttccatgaa acatctgatt atgaaaatga
     3421 ttgatattat ctgtattggt ttcccattca tctttcttac gctttaagta acggctagca
     3481 gatactaaga agccagcaga acccatagcg ggatctgaga tgatatcttt gatagtcggt
     3541 tgcatcaact caaccatcat atcgatgatg tgacgaggtg tacggaactg tccattttta
     3601 cctgcggtcg acaattttga taacagatat tcatagatat ctccgatatc agtaatactt
     3661 tgtttgtcat tatcaaaatc tacatctaat cccctagttg gaaaaacatc taagatagaa
     3721 attgcctttt gaagcgtagc aggtttattt atttgaaaaa tagcttctcg catatatcgt
     3781 gaaaaggctg tatcatctgt atcccccttg agatttttaa taaacggaaa aatctcctga
     3841 gtcattaaac gataaacttc ctgagcatct cctatatttt taaaagttga ccaacggtat
     3901 tcaggtttat cttttggaaa aactccctca taaggaatcc ctagaaattc agcatcactt
     3961 tcacgtccaa gctcgacact atccaaatct ttcataaata agagataagt caactgttca
     4021 atatttgtta aaggatttgc gtttccttct gtccaaagaa tttcccacag ctgatcgatt
     4081 ttatttttta attcgcctgt aatcatatct tcccttttct ttagttttta aaacttagta
     4141 atatcattat tttatcagat ttcaaacaaa gcttcaatta actatatcta tgcgtcacct
     4201 gaatatttta tactcttcga aaatctcttc aaaccacgtc agcttcacct tgccgtaggt
     4261 atatgatact gactctgtca gttctatcca caacctcaaa acagtgtttt gagcaacctg
     4321 cggctagctt cctagtttgc tctttgattt tcattgagta ttaatagact tgtttggtat
     4381 cctgaaaact atatcgtata ggtgtcgtca tggatccttt tagctgattt aaggatacga
     4441 aaacacaata ctatgactca attgaaatgt taaaattcaa tttctagcca cctaatcctg
     4501 cttcaaatag ttatcgaaca agttttatga tagctacctt gttaggatgc tcttattttt
     4561 taccagacaa aacaaaagga ttaagggagt gaatttcctt aatccgatag ttcttattct
     4621 tgacgttgtc cgaaatcagc aatcatctga tccatttctt gtcgactcgg agttgtcagc
     4681 atataaaagt aatctccttg aagttccgca aaagcctctg gcatgatttt tttaaccttg
     4741 aactgctggc tatatttggc aagtaagttc tcctcagaat agacatagtg agcatttgca
     4801 cgacgtgatg tagccaaaca atactgaggt tcaaactctg acgctgggaa ctcttctcct
     4861 gcgacaatgg ctgcatatcc acgatagagg tccaaggaat gagcaaagtt ataaacatca
     4921 atggtgaaac cacctgcagg gcggttattg tactcaatgg taatataatc gtccccctca
     4981 cggaagaact caatatggaa aaaccgttct ttcataccaa attccttaac aatcgcttcc
     5041 ccatacttgc gtagtttggg aaccatatcc ttgagcacat agtaggaatt gtccatctta
     5101 taaatcatga gatcaagcgg tgtataggcg tagtcaaagg ttgttgagaa aacaatcttt
     5161 ccatccttgt tcacgagccc gtcaaaggta cagatttcgc tggaagtgac aaatttttca
     5221 aagaaataaa gggttgaatg gtcccattct tgcttgaagt gattgatatc gtcttctgtc
     5281 tcaagtttaa aggttgcggc tgctcccact ccattatcag gtttggcaat cattggaaga
     5341 ccgatttctt tcactgcttg ataacagctc caggtaccac aggaacacct gcttttttga
     5401 aaagtttctt catttcagac ttatatttcg tctttttgag atcctctggt ttggcaccaa
     5461 aaacattgaa ttgttctctg agtgttgcgt ctagctcaag ccagtattca ttgtgagact
     5521 cgatgcggtt aattggacca tgtttataaa agagaaaagc cactgcacgt ttgacttcat
     5581 ctatgttctc aagattatca acacgaaaat actcggtcaa gctattgcgc aagggctcat
     5641 ccaattgctc gtaagactct tgaccaattc ccaagactgt gatgccttta ttagctagtt
     5701 cgatggtaaa ctgttgaaag ttttgtggat agtagggaga aataacaagg taattcatag
     5761 gtaactcctt ttataaatag agattaccga ggaaataagg catttgttta cgccatcatt
     5821 cccagtcgtg ggcgacatca tgtccccatt cagcaaacca ggctggaatt tgtttctggt
     5881 caaaggcttc tttgagcttg taaaaggatg gcaaaccatc ttgttcccag gctccaagcc
     5941 ccgtacacag cacaatctct gcctgacggt aacggtcaat aaaccagcca tcgttttggt
     6001 tccaaatata atctactggc gagttttggt aaatagcatc atcgttgtag taatcaccga
     6061 caaagaaacg tgcgtcgtaa acaccactga gagcaatcac tttagtaaag acatctggat
     6121 gctggaggaa gaaattgagt gcatgatagg ctcccataga gcaacctgtc gtcatcatgc
     6181 catcaaacca acctgtcttg tgcttgataa aaggaatggc ctcctcaatc acataacgtt
     6241 cgtaggcacg gtgcatttcc gcttggtcat gagcattttt ccaagtagcc aaccaactct
     6301 cactatccaa actagatagg gtaaagaact ggacaaggcc ttcctcgata aaggaagcac
     6361 aggcatcaat catgccaaaa tcatagtatt cgttgtgact accacctgat gaagcaaaga
     6421 ccacaactgg aatcccacca tgtccataac ggttaaggta catttcacgg ttaagatgac
     6481 cactccagtg gctaagatgt tcaatatgca tttcgttttt tcctttctta acttaccatt
     6541 tttctgcaaa aaatctcaga caatctggta gattttctga ccaagggatt tcactatgga
     6601 tggcaccaga ctgaactttt agcacaagat tatccagatg tactccccct gctatcaaat
     6661 catggtaata gcaaagcgac gagtcgatat aggcttgttt gatattgcca tccatcaagg
     6721 tcttgtctgt atcatctgct tcttctgttc ctacatagat gaagatgcgc tggtcaggcg
     6781 atagtttctg gcactcgata tagcggttaa aggcttcttg gtggagccag tttgcagatg
     6841 aaaaaacgcc caagcaacca atttggtctt ggtattccaa accgataaac tgggtaatat
     6901 tgcctcctag tgaggaacca atcatagccg tatgctggca gtctgctttt gtacgatagg
     6961 tctcatcgat aaaaggcttg accacctcca tgacaaactc agcatactcc acacccttac
     7021 caccaaactg ctgctctggg ataggagatt cttggaactt ccaagccgca tactcattca
     7081 ttcgccccat accatcattg tcaatagcaa cgacaatcat gcgactgata tccggatttc
     7141 gtttgatagc tgggataatc ttccatgaat atccaatgaa agactctttg ctataaaaaa
     7201 cattttgccc gtcatgaaag tatacaacag gataggaacg gtctgtatct ttctcataat
     7261 ctttaggaag aagaatacgt acacggcgct ccttacctgt ataaggaacc ttgagtttgt
     7321 gttctttcat ttttagataa aagtaggatt gattcattgt cagaaaactc tctatattca
     7381 aaattttata tcattatatc atgaaaatag aaaaaagtta gttttttacc tgtttttaga
     7441 aaaaaaaact aacttttttt actgattttc gctattcttt tggattttct gaattagagt
     7501 agattatcaa tcaagtcatc aacttcatct ttttcggctt gaggtgtgat ttcagtaatc
     7561 atgattccag ccactgctcg ctcaaccaag ccttcaacat ccatacgcgc ttcgtactgc
     7621 tccgcattct taattttagg atttgttttt ggacgatctg gtgcaaaaat ggtacaacag
     7681 tcttcaaacg gttggattga aatgtcaaag gtatcgattt cctgggcgat gtcaatgatt
     7741 tccaacttgt ccatggtaac cacaggacga atgatgggag tgttggtaac agcattgata
     7801 gccttcatac tttcaagggt ttggctggct acttgaccta gactttcccc attgatgata
     7861 acaaaaccat ttcgtacctc acgaatacgg tcagtaatcc gcatcataaa gcgacgagtt
     7921 agagtcatca aataagcttc tggcgctttg gctttgattt cctcttgaat ctctgtgaaa
     7981 ggcacctcga taaactggat atttccgcca aacttggtca atttacgggt caagtcctgc
     8041 gctttcttga gggcaccagg actagtatat ggtggactag caaagtgaac tgcctcgata
     8101 tccaccccac gcttaagagc aagataacct gctacaggtg agtcaatccc tcctgacaac
     8161 atgagcatcc ctttacctga agttccaact ggcaaaccac cagccccacg aatggtttca
     8221 taagaaagat aggctgcttc ttcacgaatc tccacctgaa gattgatgtc aggacttttc
     8281 atttgaactt gcacatttgg aatggcttcg aatacagccc ctccaagtgt ttggttgagt
     8341 tcacgactat caagttcaaa gttgtggtcg ctacgcttgc tagaaatctt aaaggtcata
     8401 ccttccttgt agatgtcccg cataatctct tggacagaag acttcaaaac ttctacagat
     8461 ttttcaacct tataaacagg agaaaagttt tgaattccaa aaacttgttt gagagattct
     8521 gcaactgctg tgtaatcagc tccattgagg taagcgtggg cacggtcgcg atctgctgtt
     8581 accttaactt gggtatagat agacaaaacg tccgaaatat tattacgaag tttattgatg
     8641 aaacgcatac ggtttttacc cttggttgac aactctccgt agcgaatcat aatttctgaa
     8701 tactgcatga atgctcctat cttacttttc tagtttgatt gtaaatcaat tttaacttgg
     8761 tcaaaaactg ctcgacctga ctcatatcat tttccaagtc taggctaaga cgcacagctg
     8821 acttggcctt atctttgtcc actcccatgg caatcaaggt accggctggt tttcctgcct
     8881 tagatgaaca agctgaggtt gttgagatga aaatatcata gtcttcaaag gcgtgaacga
     8941 tgacttcacc tcgaacacct ttgattccaa aagtcagaat atgaggtgca aagtcttcct
     9001 catctgaaaa gacaaaaata tccggatagt tcagaagagc ttggtgaatc actgccttca
     9061 tctgcccagt cttgctccta aagatatcta gcttttccat agataaacgg agagccttgg
     9121 ctgtcgctgc aatccctgcc acattttcag ttgtcgaacg ataatctcgc tcctggccac
     9181 cacctgtaag aagaggtgta atcttcttgc cagatttgat atagacaaag ccaacaccac
     9241 ggacaccatg aaatttatga ctcgagaagg tcgcgcaatc cacccgttct gtcagatact
     9301 tttcagtcgg aattttggca agcgcctgaa ccgcatcaac gtggaaggaa atagtcggct
     9361 tgtctgccaa gaattctgaa atagcctcaa taggttggat agagccgatt tcattgttca
     9421 cagccatgat ggaaacgagg attgtatcag gccgtatcaa acctgctaac gcctcaacat
     9481 cgaccaagcc tttcttatca actggagcaa aatccacttc aaatccttga cttttcaacc
     9541 agagggctga ctctttgact gctggatgtt caatggctga aacaatgatg tgcttgccaa
     9601 actgagcttt ttcaaaggcc acacccttga taacccagtt atccccttct gttccaccag
     9661 aggtaaagaa gatttcatcg cttttcttac cgattaaatc tgcaatctgt tggcgagaag
     9721 catctaagat tcgtgttgct tggtctccca aacgatggag actagatggg tttcctaaaa
     9781 tttttgaagc gacctgcata taggtttcaa gggcttcagg ataaggcttg gtcgtcgctg
     9841 aattatcaaa gtaaatcatg tttctcacgc tttctaaaat cactccctct attgtatcat
     9901 gaaacggagc ttgcgacaag aaagggcaat ttctcttttt ttaagatttt tttaaagaaa
     9961 cagagtataa taaatcataa tcaaaggaga gaatgtatgt ctaactatcg tagaacttca
    10021 aaaccgaaaa cagaacatat caaaaaaggc tttactgttt ttcaaaaaac cattactact
    10081 atcggtagta tccttggttt gattacagcg ggtatcacga tcatgaacgc cttggataat
    10141 aataataaaa atactaaaaa agaacctacg acaagccaga cgacaacctt tgtcaaagaa
    10201 attcaaaaag aatcccctca ggaaaatact actccaaata aggaaaataa cacttctcaa
    10261 gaaaaaacac aacaagaaga aacgccaaaa tctagcgtca aggaagagaa aaaaaaagat
    10321 cagaaaacag caactcagga ctctactaca cctgctacaa gtaaacctgc cactgaaaat
    10381 gaaaaacagc ccaatactcc aacttcagaa aataatactc aatgaaaatc aaagagcaaa
    10441 ctaggaagct agccgtaggc agtacttgag tacggcaagg caaagctgac gtggtttgaa
    10501 gagatttgcg aagagtataa aagtaatcaa tagccagtaa aatagctcct tccaaccttg
    10561 gaaagaagct attttttatt gctgcaatac ttttcttggc ttggtacctt cagctggacc
    10621 aatgacacct gccatctcaa gctcttccat gagacgggtc gcacggttaa atccaactga
    10681 caaacgacgc tgaatcatgg atgcactggc tttctgtgtt tcgataacca aagacttagc
    10741 ttcttcaaaa agcggatcac caccagcatc tccatccgaa aattctcctt cattttcaga
    10801 aacctcacct ggatcaaaac tctcatcgta gtctgcatct gcctgagtct tgatgaagtt
    10861 cacaatgcgc tcaacatcgt catccgagat aaaggagcct tggagacgaa ctggatgatt
    10921 ttcattaatc ggtttaaaga gcatgtctcc tcgaccaaga agtttttctg ctccattttc
    10981 atccaaaatc gtacgggagt ctgttcctga tgaaaccgca aatgctacac gagatggaac
    11041 attggcctta atcaaaccag agatgacatc aacagatgga cgctgagttg caagaatcat
    11101 gtggatacct gcagcacgcg ccttctgccc aagacggatg atagcatctt ccacttcctt
    11161 gctggccacc atcatgaggt cagccaactc atccacaatc acgacaatga atggtagcgg
    11221 aatttgcttg tactcagact gggaattgaa ctcttctacc ttggcattaa aacctgcaat
    11281 attccgaact cccaccttgg caaagagttc ataacggttt tccatttcat ccacaacctt
    11341 ttgcagagcc ttgctggctt tgcgtggatt ggtcacgact ggaatcaaga ggtggggaat
    11401 atcattgtaa acagataact caaccatctt gggatcgacc atcataaatt taacttgatc
    11461 tggtctcgcc ttcatgagaa tgctagcaat aatgccgtta actgctactg acttccctga
    11521 acccgttgaa cctgcaacta gcaagtgggg cattttagaa aggtcaaaag ctcttgcggt
    11581 tccattaaca gccttcccta aaggaatttc caagaaattt tctgctttcg tttgcgattg
    11641 ttcccatagt tctcggaaag atacagtggc aatatcggag ttgggcactt caattccgat
    11701 tagagatttc ccagggattg gtgcttcaat tcggacatcc ttggcagcca aggctagagc
    11761 gaggtcatct gatagattgg aaatgcggtt gacccttaca ccaacagccg gcttgacttc
    11821 atacttggtc actgatggcc caatttcggc ccgttcaact gttaccttaa taccaaagct
    11881 agcaaaggtt gcttctaaga ttttgatatt ttctctgaca attttcttct ctttagactg
    11941 atcttttggt ttatctggtg caaagagttg taagcttgga agtttgtatt caagggcttc
    12001 tttggctgaa aaatcgacct gaacatcttc gtcatctgag tcatcttcct gttcagggaa
    12061 tttaagttca gcttgaggca ggatgatttc tggttccacc cacttttctt ctggaatagg
    12121 tggaagattt tgaacagctt cctctgtcag aatttcaccc gtttccatat caacaggagg
    12181 caaatcgagt aaggcttttt cagtctcttc ttgttctaat ctagcctctt tctcagcctt
    12241 ttggcgagct ttttcttctt gtttgacaaa gcgttcctct tttcgacgct cgtgcccttc
    12301 ccaccatttg gcaaagcctc tactgaaaaa ttcagcaata tcgtaaacag accaagggct
    12361 gactaggaga gaacccacta aaatcaagat agaaccaata aagtaagttc cgatatttga
    12421 aaagagaaag gctgttggaa tataaagagc gaccccgatc aagccccctc cagcaaagct
    12481 agtcgttcga aaaccagtca gatctgtcac aacctgagcc atggtccctt ttagaacgga
    12541 cttgtccaaa ccatatttcc aaaccaagta ggcctcaaaa atcaagagta agccagcaaa
    12601 tatggtgaaa aagccagata agagtccttc ctgttttcgt atccacttga aaaagaagag
    12661 atagattaat aggccgaata tcgccagata agctaggcta cccactagca agcgaattaa
    12721 attataaagg gttatacctg cagcccctaa tttgaaggct gcgaaaatca ataaaatcgc
    12781 aattcctaac gaaatcaaca ttcgttgaat cgcttctttt ctttccagtt ctgctttaga
    12841 cggtctccgt cttgttgtac ttgtattctt gtttgccatt cttctattat accatatttc
    12901 acaggcattt cgggaagaga aaaagactgc accaaacggt ccaatctttt catttttcta
    12961 ttttttatgc ttgtggtttg cgtaggtaac cataaaccac accacttacg attgctccta
    13021 ccaagacaga aacgaggtaa aggagagcat ttgaagtaag ggcgataacg aagattcctc
    13081 cgtgtggcgc catgagtttg ataccagtaa gaccaacgag tccacctgct actgctgaac
    13141 caaggatgaa gcttggaatc gcacgagctg ggtcagcggc accaaatgga atcgctccct
    13201 cagtgataaa tgacaagccc atgatgatgt ttgtcaaacc agagttacgt tcttccttag
    13261 taaatttatc tttgaaaaga agagttgcga caaagattgc aagtggtggc accattcctc
    13321 cagccataac tgctgccatg gctacagaac cacctgaaga aacagttgct gcaagcgtac
    13381 ctgtaccaaa gacataagct gctttattaa ctggtccacc catgtcaaca gccatcattc
    13441 caccaaggac gataccaaga aggacagctg aacctcctcc aagaccgcct aggaagtcat
    13501 tcatagcagt gttgattgct gccattggga tattcacagc taacataaca aatcctgtca
    13561 agattgttcc aagaagtggc aatagaagga ttgatttagc accttcgagt gaacgaggaa
    13621 ctttaacgta tttcttgatg gcaagaacca aggcacctgc gataaatcca ccaacaaggg
    13681 cacctaggaa accagatgag acacctgcaa gagttgaagt tgcttcacca cctgcggcat
    13741 aaggaatttt accaaaggca aaaccttctt tggcaatagc accagccacg aaacctgcta
    13801 ccaaacctgg tttttcagca atagagtagg caacataacc cgcaaagact ggaagcatca
    13861 aaccaaaggc agctccacca attttcatga acatagaagc taactcatgg taagaaccaa
    13921 gattgccaag gttttcattt ggaacactca aagcaccgtc aatcaagaag gcaagggcaa
    13981 tcatgatacc accaccgata acgaatggta acatttgaga tacaccactc atcaagtgtt
    14041 tgtagaaggc accaccaagg ctttgttttt cgttagaggc tgttgcgact ttggcaccat
    14101 tagcggcacg gtagacttcc gcatctcctg aaatagccaa gttgatcaat tcttctgtct
    14161 tacggatacc gtcagcaact ggacgattga tcaaaggttt gccatcgaaa cgatccattt
    14221 caacggcctt gtctgctgca atgataataa ctttagcctt acggatatct tctgcagtta
    14281 gttgatttcc aacaccgcta gcaccgttgg tttcgacctt gataccaacc cccatttcag
    14341 cagctacttt ttgaagggct tcttgggcca tgtaagtgtg ggcaatacct gttgtacaag
    14401 ctgtaacagc tacgataaag tcaccagagt cattagcagg tgcttgaaca agttcctcag
    14461 ttttttctga agcttggtca aaaagttcga taacttggtc tgcagatgtt gcttgacgaa
    14521 gtttgtctgc aaaaccgtct ttcatcaagt attgagacaa ttctgtcaat gctgccaagt
    14581 gagtatcatt ggcaccttct ggagctgcaa tcatgaagaa gaggtcagtt gcctgcccat
    14641 ccaaactctc atagtcaaca cccttgtttg acttagcaaa gagaactgtc gcttctttga
    14701 cagcagcgtt tttgctgtga ggcatagcga ttccatcacc caaaccagta gaagttaaag
    14761 cttcacgcgc caaaatgcct tctttaaagg tttcaaaatc tgtcacataa ccgtggcctg
    14821 ttaggctttt aatcatctct tcaatgacag cagtcttttc agttgcctgc aaatccagca
    14881 acatgacatc ttttctcaat aaatcttgaa ttttcatcgt ttttctacct caacttttcc
    14941 atatgtttct ttaataaatt ccgccgttgc caagtcatct gagaaggtag ttgccgttcc
    15001 gcaagccact ccccatttga aggcttctac tgcgtctttt gatttgacaa attcacctgt
    15061 gaatccagca accatagaat caccagctcc aactgaattt ttgactgttc ctttgattgg
    15121 tttagcgaag taagctccct cagatgtgac aagaagggca ccatcaccag ccatagagat
    15181 aataacattt tgagcaccct tagccagtaa ctcacgagcg tatttctcaa tttcatctaa
    15241 actttcgagt ttaaccccaa aaatcgctcc aagttcatga ttatttggtt ttacaagaag
    15301 aggctggtaa tccaaactat caattaaggt ctgtccttca aagtcacaga ccacttgcgc
    15361 accagtctgg cgcgtcaagg aaatcaaatc cttatagata acattgccta gatttttagc
    15421 acttgaacct gcaaagacaa ctgtatcttc tgctgtcaga ctagataaaa tagctttcaa
    15481 ttcttctagc ttaaccggtt caacagttgg acccgttccg ttgatttctg tttcttggtc
    15541 tgctttgatt ttaacattga tacgagtatc ttctgccacc tggacaaaac gtgtctcgat
    15601 ttcttcctct gctaaagtat ctgtgataaa tttaccagta aagccaccga taaatcccgt
    15661 cgctgtattt gatatattca aacgtttcaa gacacggctg acattgattc ctttcccacc
    15721 agcaaactta tcatcactgt ccatacgatt tacactacca actttgactt ggtccaaacg
    15781 aacgatatag tcaatggatg gattgagtgt gactgtataa atcatacttc tattacctcc
    15841 gttttctcct taataacctg caagagctca tgcccttgac tagtgataac gatagcgcgt
    15901 ttgagtgggg ctaccttggc aaagcaagtt tgtccaattt ttgacgaatc caccaagacg
    15961 taggtctgct tggcattctc caaaatagct cttttcacag ctccctcctc catatcagga
    16021 gtcgtataat agccatcgtc aacaccattc attccgataa aggcacggtc aaagtgcaat
    16081 tggttaatct ggttaagagc aacgcccccg atactagcat ctgtcgccgt cttgacgttt
    16141 cctccaacca tgacagttgg aatctgcttt tcaaccaact gagcggcatg gtgaatggag
    16201 ttggtcacaa ctgtaacatt cttattgacc aattcatgaa tcaaaaaagc agttgttgtt
    16261 ccagcatcga taaagatgac atctttttct ttaatgagag aggctgcttt ctgagccagc
    16321 aatttctttt cttgaaggtt tttgacagat ttttcttgaa tggtttcttc ttcctgtaag
    16381 gagtggggga gttctgctcc accatgcaca cgacgaagct tattttccgc ttccaactca
    16441 tccaagtctc ttcgaaccgt tgattctgac gtttctagca aactaactaa tttttctaga
    16501 gaaactacat gatgttgatt taactcctct agaatcagtt gtttacgttc tgtttttaac
    16561 actgaatcac ctcctgttat cgtttacact attcattcta ccatacttta tttcgaagtc
    16621 aagcattttt tatcattttc tttcaaaatc tatcattttt cttatttcta gaatttttat
    16681 tgcaagataa gagcctttat ggtagactat ttgagtaagt attggaagat tactcaagag
    16741 gcttaagagg ccgtgttgga aacgcggtag gcgtgtaata gcgtgcgtgg gttcgaatcc
    16801 catgtcttcc gtcgaaaaaa gattattttt aggatgcaac aaatgttgta tcctttttta
    16861 aaatagggtc tgtttgtgac tcccttttta gcaaaagaat gcaaaggaat accaaagata
    16921 aaaataaaaa acgttgattt aacaacgttt taccaaggaa tgcaaaagaa tgcaaaggaa
    16981 taatggagcc ggtgggagtc gaacccacgt ccaaacacct gccaacatat ttgtctacaa
    17041 ccataggtta tgtattattt taacagcccc tcgacacata actcaagtct agaaactgcg
    17101 agtctatcaa tctcttatca agccgctaga caaggcttaa tcgtatctcg ctaataataa
    17161 gacctgtcat tgaacacgag caatccaaat cgggtcacgc ctgctggttt ttaggcagct
    17221 agagcgtaag aagtgttatt ttttgcagtt atatttaact gagcgtttac gtcgccacac
    17281 gagtcgcaaa atatgcctca taatgcctgt cgaatccgta acgaccccaa aagacaataa
    17341 aaccattata ccttatctaa ctcaaaaatg caaaaagaaa tcacatacct aaaaaagata
    17401 ctattcgaga aatttagcaa actggaagac taactacaac tttctcagtg cataacttta
    17461 cgattgtaaa tagagcttac gaaatccaat taacacatac ctaagatgaa gctatctgtt
    17521 ttgaagaaat tcacgaagag aattattcta aaatactttc agatgagaat tttcgtactc
    17581 tctttatttt aattcatttg agtttaaaaa ctataaaatc aatccttata ttattcggac
    17641 tacttttcac ttattgcacc aaaatatagt aaaatgaaat aagaatagga cgaatagatc
    17701 aggacagtca aatcgatttc taacaatgtt ttagaattag aggtgtacta ttctagtttc
    17761 aatatactat aaataggttt cattcgaact ttaatagact atgaaaacca gtggaactta
    17821 ccctgacacg gaattccact ggttttttcg atttttatca gattaacttc tactattctt
    17881 agctgtgaaa attagtttaa gactttaact tattttcagt cttctaatct aaaggccact
    17941 tccagtaaag aaaaatcagg gttctcctga cttttactta gctaattctc tttctcgttc
    18001 tttcattatt ttatgatttt catacaaacg ggataagaac ttagaaattt ctttcaagat
    18061 agaataggtt ggcactgcga caatcattcc aactacacca taaatattgc ttgacaacaa
    18121 aagtaaaact aaaatcgtga ttggatgaac cttcataaca cttcctacga ttcgaggata
    18181 taagatattg ccatctacct gctgaacaac aagcatataa atcactgcaa tcagcagtct
    18241 atggggatca gtgaatatat ttgcgatgat cataggaatc aaaccaatac ttggccccac
    18301 ataaggaatt aaattggcta caccagaaaa aatggcaaaa actaaagcat attttaaacc
    18361 aataatacta tagccaatat aagctaaaca acctataatg attgcgtcaa tcgaaactcc
    18421 actaatatag cgagcaatcg tcgcatttaa attctttaat aagcctgcaa tatgcaagcg
    18481 atccctcttt agaatcgttc tttcaagcat gggcaagaat ttatgtccat ctaataagaa
    18541 ataaaccaaa aaaactggag tcataatcaa aatcaaaaca gtactgataa gagctgacaa
    18601 gacgctcccc acactatttg atacgctatt taggatattt tgaagaatat caacatagga
    18661 taagtttaac tgctgaattg tagcttctac atccaaattc tggagcgcag gataattaga
    18721 taagtctatg attaagtctt gtactcgact ataaatagtt tgactagata taatcaaact
    18781 agataactga ttaatcaaaa taggtaagag atagacaaca cctatgacca ttccccagac
    18841 caaagtacac aaggtaatta aaataccaag caaacgattg agtttacaga ctttatttaa
    18901 gaaagtaaca atagggtttg tcaaataata aagaaagccc cctaataaaa atggaatcat
    18961 aattgtatta agcacgctaa caaaagggtt aatcaaagac cccatctgtc tccataggta
    19021 aaagatgatg gttaagagta aaatttctgt ggtccaaaaa aataatttat ttctacgaaa
    19081 catgagttac ctccctcact ttattttacc atattttcaa aaagcttaac agatgaatta
    19141 ttaaagcaag aatatttttt ttctttatga tagaataaga ctactatgaa aaaaatattt
    19201 ttaactttgt taactgtctc tcttttaggg ggtgcttcta ctgctgttgc tcaagatttt
    19261 accattgccg ctaaacatgc gattgctgtt gaggcaaata ctggtaaaat tctctatgag
    19321 aaggatgcaa cgcaacctgt cgaaattgct tccataacaa aattgattac tgtttatctg
    19381 gtctatgaag ctttggaaaa cggaagtatt accctctcca ctcctgtaga tatttctgat
    19441 tatccttatc aattgacgac aaattctgaa gccagtaata ttcctatgga ggcccgtaat
    19501 tatactgtcg aagagttgct tgaagcaact ctggtatcta gtgccaacag cgccgctatt
    19561 gccctagctg agaaaattgc tggctcagaa aaagatttcg tcgatatgat gcgggcaaaa
    19621 ctcttggaat ggggaattca ggatgccact gttgtcaata cgacaggtct taacaatgaa
    19681 actctagggg ataacattta cccaggttct aaaaaagatg aggaaaataa gcttagtgct
    19741 tatgatgtcg ctatcgttgc tcgcaacctc atcaaaaaat acccacaagt cttagaaatc
    19801 accaaaaaac cttcttctac ttttgctggg atgacaatca cttcaaccaa ctacatgtta
    19861 gaaggtatgc ctgcttaccg tggtggtttt gatgggctaa aaacaggaac aacagataag
    19921 gctggagagt cttttgttgg tactactgtc gaaaaaggca tgagagtcat cacagttgtt
    19981 ttaaatgcag atcatcaaga caataatcct tacgctcgat ttacagctac atcttcccta
    20041 atggattata tttcttctac atttacactt cgcaaaatcg ttcaacaagg cgatgcctat
    20101 caagatagca aagcccctgt acaagatgga aaagaagata cagtaactgc agtggctcca
    20161 gaggatatct atctaatcga acagattggg aatcaatctt cccaatctgt tcaattcaca
    20221 cctgattcca aagcaatccc agcaccactt gaagctagaa cagtggttgg ccatttgact
    20281 tatgaagaca aggacttgat tggtcaaggt tacatcacca cagagcgccc tagtttcgaa
    20341 atggtagcag acaagaaaat tgaaaaagcc ttcttcttaa aagtttggtg gaatcagttt
    20401 gtccgctttg ttaacgagaa attataaaaa atcgcgattt taaaccgcga ttttttgata
    20461 caagttcatc ttcaaaatcc ttgattttga gtaaatctaa tactcaaaat caaagaacaa
    20521 actaggaagc tagccgcagg ttgctcaaaa cactgttttg aggttgtaga tgaaactgac
    20581 gaagtcagta accatacata cggtaaggcg atgctgacgt ggcttgaaga gattttcgaa
    20641 gagtataaaa tcaaatttta tccaactgat ccctccattt catagctaat caagcggttc
    20701 agctcaactg cgtattccat tggaagttct tttgtaaagg gttctacaaa tcccatgaca
    20761 atcatttcag ttgcctcaga ttctgacaat ccacggctca tgagataata caattgctct
    20821 tctgaaatct tagatacttt ggcttcgtgt tccaaagcca cttgcgagtt gtgaatttca
    20881 ttaaatggaa tagtatctga tgctgacaag tcatccatga taatggtatc acattcaatg
    20941 tgggaaacag atttcttaga gttcttgtta aaggtgactt gtccacggta gtcaaccttt
    21001 cctccacctt tagcgatgga tttagacaca atagacgagc tggtatgtgg agcattgtga
    21061 atcatcttag cacccgtgtc ttggtgttgc cctgcattag caaaggcgat agagagcatg
    21121 gtaccacgcg ctccttctcc atcaaggtaa acagatggat atttcatagt cgttttggca
    21181 cccaagtttc catcaatcca ctcaacagtg gcatcctttt gagccttagc acgctttgtt
    21241 accaagttat agacgttatc agaccagttt tggatagttg tataacgcat ataagctccg
    21301 tccaaagcaa aaatttctac aatggcagcg tgtaagctat tgcttgaata tgttggtgct
    21361 gtacatcctt ctacgtagtg gacgcttgct ccctcatcaa cgataatcaa ggtacgttcg
    21421 aactgaccta tattttcgtt attgatacgg aaataagttt gaagtggaat atctaccttg
    21481 acaccttttg gcacgtagat aaaagttcca cccgaccata ctgctgagtt gagggctgcc
    21541 aacttgttat ctgtcggcgg taccaacttc gcaaagtatt gtttaaataa gtctgggtat
    21601 tccttgagtg cggaatctgt atctgtaaag ataataccta atttttggaa ctcttccttc
    21661 atgttgtggt aaaccacttc tgactcgtac tgggcagaag cccctgctaa ataagcacgt
    21721 tcagcttctg gaatcccgat acgttcaaag gtttctttaa tcttttcagg tacatcatcc
    21781 caagaacggg ctggtttgtc agatggtttt tggtagtaga ttaagtcatc aaagtcaatc
    21841 tctgacaagt ctgctcccca agtttgcatg ggcatttttt tgaaggtttc ataagacttc
    21901 aaacggaact ccaacatcca ctcaggctca cccttagcag cagataattc acgaataaca
    21961 ccttcgttga gtccttttcc tgtcgataag acaggctcta catcgtcatg gaaaccaaat
    22021 ttatattcac caaggtcaat tggttttggt tctactcttt cttcagccat agtatccttt
    22081 ctttcttcat ttctaataat tcataagaca aaagaaactt gtcttactgt ttttcttgat
    22141 tttcaattgt tttcttaagg gcattccaag ctagggttgc acacttgatt ctttgaggga
    22201 atttggcaac acctgacaag aatgccgcgt ctccaagttg gccttgacgc tcatcttttt
    22261 gcccttgaac catttcagaa aaaatagtcg ccagttctaa aatttcttgt ttggtttttc
    22321 ctaaaacggc atctgtcatc atactagcag aagcagttga aatcgtgcat cctgaattta
    22381 gaaaagcaat atcttccaaa cggtcctctg catcaaactt gacagagagg ttgatgacat
    22441 ccccacaagt cggattgttg agactggttt gctcagcatc ttctaacttc ccttggtgat
    22501 gtggattttt cgaatggtct gctaccactg ccatataaag gctatctagt ttagaaagtg
    22561 ccattgaaaa actcctttgt cttttgtagg gcatcgacta gtttgtcgca atctgccttg
    22621 gtattgtaga tataaaaact tgcacgagct gttgctggga cttccaaata ctgaagcaag
    22681 ggttgcgcac aatggtgacc agcacgaaca gccactcctt cataatccag agccgtcgca
    22741 agatcgtgag gatggagatc acctaggtta aaggcaataa cacccgaacg ttgagccaaa
    22801 tcctgagaac cgtaaatggt caatccctca attgcctgca gttttggata gacgtacgca
    22861 atcaattcct gttcatgagc ttcaacggca tccataccaa tcttttccag ataatcaact
    22921 gcagtcgcaa gtccaatagc tcctgccata tttggcgttc cagcctcaaa tttccaaggc
    22981 aattccttcc aactagcaaa ttgctcgtag acaaaatcaa tcatctcgcc gccaaattct
    23041 actggagaca tttgctcaag atacttttct ttgccgtaaa ggacaccgat accagtcgga
    23101 ccagccatct tgtgacccga aaaggcgaaa aagtccagat ccaagtcctg gacatcaatc
    23161 ttcatatgag gtgtagattg agcaccatcc actaccataa ttgccccaac ttggtgggct
    23221 aattgagtga tttccttgat cggattgacc acaccaagaa cattggaggc atgagctagg
    23281 gaaacaaatt taaccttatc agtcaattta gctcgcaaat cctccatatc caaggcaccg
    23341 tctttaagat agacatagac aagctctgct ccagtctttc gacaagcttc ctgccatgga
    23401 atgatattag aatggtgttc cattactgaa atcaagaccc ggtctccctc agcgagaatt
    23461 tcctcagcaa agcgtgccac ccagttaagg ctggttgtcg ttcctctggt aaagagaact
    23521 tcctttgtag agcctgcatt aataaactta cgaatggttt cacgagcagc ttcataagaa
    23581 gctgtcgctc gttccgctaa ggtatggaca ccacggtgaa cattggcatt gtcctgctca
    23641 tagtaactgt taatagcttt cagaactact agtggttttt gtgtcgtcgc agcattgtcc
    23701 agatagacca gaggttcatc attgacaatc tgatctaaaa ttggaaaatc cttgcgaatc
    23761 gcttctacat ctaacatagg cttcccctta gcgttttgac aatttctctt cgatagttgc
    23821 aatcatttca tcacgaactt ccttgactgg aatctccacg ataacagatc caaggaaacc
    23881 acgaacaacc aaacgctctg cagttgcctt atccaatcca cgactcatga ggtaatacat
    23941 gtcttctgga tcaacttgtc cgatagacgc tgcgtgtcct gcagtgacat cattttcatc
    24001 aatcaaaaga attgggttag catctgaacg cgcttggtct gaaagcatga gaacacggct
    24061 ctcttgttgc gcatctgctc ccttagcacc cttgatgatg tggccgatac cattgaaagt
    24121 caaagttgct ttttcaagga taaccccatg ttgtaggata tttccgatag agttgcagcc
    24181 atagttagtt acacgagtat caatcccttg tacctgacga ccacttgaaa gagctacaac
    24241 cttgaggtca gcatggctac cattaccaat caagtcacta tcaaaatcag caacgacatt
    24301 tccttcgttc atgacaccga tagcccagtc aatacttgca tcgttgccta atttaccacg
    24361 acggctaatg taggcagtga cgttttcacc tagacggtcg atagcagcaa acttgacttg
    24421 cgcaccagaa cgtgcaatca cttccactgt gatattggca gttactttgt cacttccttc
    24481 accgcgtgac tctaaacgct ccagataact aatcttagaa tttttaccag cgataatcat
    24541 aatatgcttg ttaaacggca cattgctatc gctatcttgg tagaaaattc cttcaattgg
    24601 ctctgtgatt tctacgttat ctggaatata gagtacagca ccactgttaa agtaagctgt
    24661 gtggtaagcc gccaacttgt catcatcata cttaacagat gacatgaaga attcttcgat
    24721 cagctctgga atttcttcta aagctgagtg aaagtctgtg aagacaacac cctgttcagc
    24781 taactcaact ggagtttgtt cgaaaacagt ttgagttcct acttgcacca acttcaagtg
    24841 atgatctaaa gctgtgaaat ctggaacatt tgctgatggc tcattttctg taatcgttcc
    24901 atcacccaga ttccaacggt ggaatttgac acgctcaata actggtaatt ccaaagtctc
    24961 aatcttgtca aaagcttttt gacggagatc agccaaccag cttggttcag cgtgcatttc
    25021 tgaaaaaagt ttaatatttt ctctagtcat ttacttctcc taaaagatac gagggaatta
    25081 caattcttcc ttgtagtcgt agccaagttc ttcagctagt tttgcgtatc cttcacgttc
    25141 caaacgcgca gccaattctg gaccaccaga aaggacaaca cgaccttcca tcatcacgtg
    25201 taccacatca ggtgtgatat agttcaaaag acgttggtag tgagtgatga tcatagcacc
    25261 aaaaccttca ccacgcatgg cattgacacc tttagacaca actttaagag cgtcaatatc
    25321 aagacctgag tcaatctcgt ccaaaagagc aaatgttggc tccaacatca aaagttgaag
    25381 aatttcattg cgttttttct caccaccaga gaagccttcg ttgaggtaac gctctgccat
    25441 ttcttctttc atgttgagca attccatttt ttcatctagc ttagtaataa actcacgaac
    25501 tgaaatcttc tcatcatctt ctttacccgc attcatagcg gcacgaagaa actcagcatt
    25561 ggtaattcca gggatttctg atgggtattg catagcaagg aaaagtccca tacgcgcacg
    25621 ctcatccact tccaactcaa ggatgtttac gccatcaaac aaaacttcac ctttagttac
    25681 ttcatagttt ggatttccca tgatagcggc agaaagagtc gatttacctg taccatttgg
    25741 tcccatgata gcggcaattt ctcctgtttt cagggtcagg ttaacccctt ttaaaatttc
    25801 ttttccttca atctcaacgt gaagatcttt gatctctatt actgacatga tagttccttt
    25861 ctttttcaaa acttttacag tacttactag aaaaacgtct gatttcccca gaaatagagc
    25921 aaaaattcta taaatatact tttctagtat aacaaaaaaa agcctaaaag gctttgattt
    25981 tgtctggaag ctgagggcta gtctttccta ttaaaatgct gatcgatgac atcaacaatt
    26041 ttacccatca cataactgac tcggaaattt ctaaagagta aaattgccca aaaggctgcc
    26101 ataatatagc ggccagtcat ccaggcttca ttgaaaaaat aggtctcagc agctgtaaat
    26161 agcgccataa taataaattg ttgtttattc ataaacttat tgtatcatga aatctttctt
    26221 tagtcttcct ctaccttcac tttatcagcc aaaaattcaa atccttctgg aatcaggctt
    26281 tcttctactt ctttttcagt ttgagaagat ttggctttgg ctgaaaaggc tgcgcgaact
    26341 tctttccatt cctccatgga aatagctaaa atctcaggtg aaaaacctgc cgcctgactg
    26401 aggatattac caaacatggt attgagattg tctcgtttca tagtttgacc agcattgaag
    26461 ttagactcaa aagcaagaat agcatggtgt tcattggcag caaccggttg agaaccaact
    26521 agcagagcct tgtccggccc acctagactt tcaattacct ctccccaggc attctgcaaa
    26581 cgaattagat tttgacgtgc taaatcagga ttttcgacgg cctcttgtaa gatagattgc
    26641 actttattgc gatcgacacg atagactgtt ttgcccgtag ctggtcgact aggagctggt
    26701 gcaacttgtt taggaaccgc acctgcatta gaaagctctt gtttgagacg ggcaacttcc
    26761 tgtctcagcg tagcaatttc attttcaacc gctcctgata gagctggttc gggcttgatt
    26821 tccgccaaac ggacggtcat catttcagca taaatcttgg gctgcaaact agacttaata
    26881 tctgctaaat tcactgttgc taagcgaatc atttcaaaca gatttttttg aggaagtgcc
    26941 aaattttcta caaagactga actatgatga gtattttctc cccctgtttg aacaattaac
    27001 aagtctctta aatagtgcaa aagatcggtc acaaaacgag tcatgctctt accattgtca
    27061 aaaagaagat tcaagcaaga caaagctttg ggaacatcct gttgagacaa ggccgccaca
    27121 taatcatcca aggctgatag gctaatggtg ccagtaattt cttcagagat agcagtcgtc
    27181 agctcatttc cctgtgtcaa actcagggct tgatccaaaa tagacaaggc gtcccgcatt
    27241 ccaccttccg cccgtctggc aatgatttcc acagcctctg gttcagaact gatattttct
    27301 ttttctaaga tatagtgaat atgttcctta atatcctgtg tcttaattga tttaaactca
    27361 aaacgttgca cacgggatag aatagtagca ggaatcttgt gcaattcagt agtggccaaa
    27421 ataaagacta cattctgtgt tggttcttcc agcgtcttta ggagggcatt aaaagcccct
    27481 gtagacagca tgtgaacctc atctatgata taaaccttat aacgagcaag gctaggcgca
    27541 taggtagatt tatcacgaat ttcgcgaatt tcatctaccc cattattaga agctgcatcc
    27601 atttcaatga catcttctaa actaccgtcc gtcactgctt gacaaatata gcagttattg
    27661 caaggttcgc cacccacttg attgggacag ttcatagcct tggcaaagat tttagcaaca
    27721 ctggtttttc ccgttccacg aggaccagaa aaaagataag cgtgacttat tttctcttgc
    27781 tccaccgctt gtttaagagt cttagccaca acttcttgac caactaactg ggagaagttt
    27841 tgacttctat attttcgata aagtgcttga tacattaaga tttttcctca aacatcgtaa
    27901 agtcccatgc tgtcttttca agcaaaatag cgacaaattg ttccaaataa tctcgatcca
    27961 tagcatcgta atcctcaatc tctgaagaat ccagatccag aactccaagt aactgaccat
    28021 tcttcatcat cggcaccaca atttcacttt tagctagact atcacaagaa atatagttga
    28081 gataggtcgt cacatctcca acaataacag tttcctgaaa gtgagctgcc tcaccacaaa
    28141 cacccttgcc tagtgcaata cggatgcagg aaacacctcc ttggaagggg cctaaaacca
    28201 attcctttcc atcgaacaaa taaaagcctg caaatacggt attaggaaaa cgtgatttta
    28261 tgagagcact ggcgttggaa agattagcca aaacattggt ttcgccttcc aataggaagg
    28321 acaattcttc atttaacatt tgataacgtg attgtttttc tgattttaac atagaactat
    28381 tatatcaaaa aaggagtaga gacaaaagaa aaatcccttg tttagtaaac aaagga
//
LOCUS       DAVKAU010000022        26294 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVKAU010000022 DAVKAU010000000
VERSION     DAVKAU010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26294
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.022"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(5..501)
                     /locus_tag="VWX48_001138"
                     /pseudo
     CDS             complement(5..501)
                     /locus_tag="VWX48_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424410.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(479..817)
                     /locus_tag="VWX48_001139"
     CDS             complement(479..817)
                     /locus_tag="VWX48_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU9171771.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            1410..1730
                     /locus_tag="VWX48_001140"
     CDS             1410..1730
                     /locus_tag="VWX48_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9171772.1"
                     /translation="MQRLEVYKNYQRLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(2020..2490)
                     /locus_tag="VWX48_001141"
     CDS             complement(2020..2490)
                     /locus_tag="VWX48_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU9171773.1"
                     /translation="MRMPLKRPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVAVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(2456..3262)
                     /locus_tag="VWX48_001142"
     CDS             complement(2456..3262)
                     /locus_tag="VWX48_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9171774.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3469..4110)
                     /locus_tag="VWX48_001143"
     CDS             complement(3469..4110)
                     /locus_tag="VWX48_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171775.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4107..6215)
                     /locus_tag="VWX48_001144"
     CDS             complement(4107..6215)
                     /locus_tag="VWX48_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9171776.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKNLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6267..6518)
                     /locus_tag="VWX48_001145"
     CDS             complement(6267..6518)
                     /locus_tag="VWX48_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9171777.1"
                     /translation="MVCSILASTSVLAVWVDGGQWNYGVGWSGNFGYSDYLHSTRSHT
                     ATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            6970..7290
                     /locus_tag="VWX48_001146"
     CDS             6970..7290
                     /locus_tag="VWX48_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9171778.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(7341..7928)
                     /locus_tag="VWX48_001147"
     CDS             complement(7341..7928)
                     /locus_tag="VWX48_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9171779.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            8170..8841
                     /gene="sdaAB"
                     /locus_tag="VWX48_001148"
     CDS             8170..8841
                     /gene="sdaAB"
                     /locus_tag="VWX48_001148"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU9171780.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            8850..9722
                     /gene="sdaAA"
                     /locus_tag="VWX48_001149"
     CDS             8850..9722
                     /gene="sdaAA"
                     /locus_tag="VWX48_001149"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU9171781.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            9744..10376
                     /locus_tag="VWX48_001150"
     CDS             9744..10376
                     /locus_tag="VWX48_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9171782.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            10426..10503
                     /locus_tag="VWX48_001151"
                     /pseudo
     CDS             10426..10503
                     /locus_tag="VWX48_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10859..12709)
                     /locus_tag="VWX48_001152"
     CDS             complement(10859..12709)
                     /locus_tag="VWX48_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9171783.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(12751..13908)
                     /locus_tag="VWX48_001153"
     CDS             complement(12751..13908)
                     /locus_tag="VWX48_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9171784.1"
                     /translation="MSSKVSGFQDKNGKVWKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            13966..15132
                     /locus_tag="VWX48_001154"
     CDS             13966..15132
                     /locus_tag="VWX48_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU9171785.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            15271..15597
                     /locus_tag="VWX48_001155"
     CDS             15271..15597
                     /locus_tag="VWX48_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9171786.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            15584..16177
                     /locus_tag="VWX48_001156"
     CDS             15584..16177
                     /locus_tag="VWX48_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU9171787.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            16170..17081
                     /locus_tag="VWX48_001157"
     CDS             16170..17081
                     /locus_tag="VWX48_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU9171788.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            17143..18207
                     /locus_tag="VWX48_001158"
     CDS             17143..18207
                     /locus_tag="VWX48_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171789.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(18385..19245)
                     /locus_tag="VWX48_001159"
     CDS             complement(18385..19245)
                     /locus_tag="VWX48_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU9171790.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(19520..20506)
                     /locus_tag="VWX48_001160"
     CDS             complement(19520..20506)
                     /locus_tag="VWX48_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU9171791.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(20778..22253)
                     /locus_tag="VWX48_001161"
     CDS             complement(20778..22253)
                     /locus_tag="VWX48_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU9171792.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(22463..23386)
                     /locus_tag="VWX48_001162"
     CDS             complement(22463..23386)
                     /locus_tag="VWX48_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9171793.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(23400..24329)
                     /locus_tag="VWX48_001163"
     CDS             complement(23400..24329)
                     /locus_tag="VWX48_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9171794.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(24648..24998)
                     /locus_tag="VWX48_001164"
     CDS             complement(24648..24998)
                     /locus_tag="VWX48_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171795.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
     gene            complement(25424..25579)
                     /locus_tag="VWX48_001165"
                     /pseudo
     CDS             complement(25424..25579)
                     /locus_tag="VWX48_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         7986 a         5605 c         4642 g         8061 t
ORIGIN      
        1 tatctcattt cttattttta aataattcat actctttttc tctgataaag ggaactgaaa
       61 aattagaaaa aattatcaga attgaaaaca gatatacgtc tttttgtatc actaaaacat
      121 aacctaaaaa tatatagacc atcaaatcta gtacaaaaag agaaaatatc ctccttttca
      181 ttaccttact tgccttaaag attctgttta atagaacctt tatcgtagta tctacacaaa
      241 tttttatcaa aaagataaga gccaatacac ctgctgctgc accaataagc caacctccaa
      301 ggcctccaac cttaatatag tttattagtt tttttgttaa aactgcagct ccagtcaatg
      361 ctataaaagt tcctgagctc atagctaaag ctgcgcaaat tccttgacaa gcactcttgc
      421 ttaaataagc ccccccccat caagatacat catctcctct tgctcaagag caacataatt
      481 atttggtaat acgagttcca tttattttct cctttatact atgtaatacc acaaaatgat
      541 tttgacctaa atcattctta acttgaagaa tcgcaggaaa tgttaatttt ggagtcaaat
      601 cttccagtgc cactcgaaca gcttttactg taaaattcaa cttattcaga cctgaaacaa
      661 taccactgac agtcgttcca tacatgtctg taccaataat ttcccgaatc ttcatgattg
      721 atagttcctt tttgtaagat aaaagaactg ttgaaacaac tgccgcagca caatctgact
      781 gatcatgttg catcgtacaa ggatattttt ttaacataga aatactcaat tctttagaat
      841 taatctaact tttctttgat gtcacccaaa cctcaatcac tgcccagtag ttcttgaatc
      901 agtttatttt caatcgtatc attctttgtt cttgatatct ttccaagcat tgtagtacag
      961 cagatttttg tccaaggact aagcctcctt taacaactca agctccctta cattatatcg
     1021 accagcccca tggaaagatt atggccagac taatcaatga tatcatacat actagaatac
     1081 aaaatatttt tttattcata ctttttctcc tatctttatt ttctacctac atcatacctc
     1141 ttattaagct cattttaaaa ttacgttaac ttttttcacg aaaaggagaa aattatgcgt
     1201 tatgattatg gatagcgctt tcaaattttt aaactcctat cccgtccttt tatctatata
     1261 ataagcataa gcgaaaatat aataactgtc aagtatctga agtgaatttt ataaaaaaat
     1321 tacaagccaa atttgtaaag tttacactaa gccgctaggg caatcgtcta tcagaatgtc
     1381 cgtttatttg tcaataatcc gagaaaatct tgcaacgctt agaagtctat aaaaactatc
     1441 aacgtttata tgacttgcga atagcaatcc tgctcaacct ttccacactc tatctataca
     1501 atcaagataa aaacatgtgt aagcaaatct gctacacttt actggaggac gccaagaata
     1561 agaaaagcta cgataggctg gctatctgct atgttcgtat tgggatttgt agggataatg
     1621 ctaaacttat ccaaaaaggt ttctcactcc tagagctgac cgaggaaact tctatgctgt
     1681 ctcatctcaa aaaagaagta gagacccatt atcaaccaaa gaaattataa aaaaagtcga
     1741 gggatttcct cgactcttta catattattt gttcgttagt tcttaatatc agccattgtt
     1801 aaaccagaag tttttagctc tgccaagcca catagtgtgt ttacttctat gtgtccatgt
     1861 caccatgaat cgccgaacga tttaacgaga aagtatgact tttacgttta tcccaactca
     1921 attatgacat ttttttcaaa agtcaatata tctcactttt tcaacgacaa gaaagaggct
     1981 gataatctac caacctctta ttctgaaccc atcactccat cactttttag cttcattcgc
     2041 tttcttagcg actgcaatct ggtattcgac ttggtcattc cccttacctg tacaaccatg
     2101 agcaattgta gtcgctcctg tctgatgcgc tatttcaacc aattttttag aaataagagg
     2161 gcggctcaag gcagatacca aggggtactt ttgttcatag taggcatgtg actggagagc
     2221 tactagcaca taatctgtag caaattcgtc cttaacatca atgacataag attcgactgc
     2281 cccaacctta agagccttat catggatgaa atctaagtct ttcccttcac ccacatccat
     2341 acaaactgca acaacatcat agtctttctt cagccaggta atagcaactg atgtgtctaa
     2401 accgccagaa taggccaaaa ttactttttc tttactcatg ttcttttcct tctttctatt
     2461 tttcaatgga cgctttaaag gcatcctcaa tgagtttgtc taattcccca gactccttca
     2521 acttttgaat ggttttatcg actgcctctt tcaattcctt gctatctttt ttcatggcta
     2581 ccgcatagga atcatcttgc tctttttcaa aattgaggtc tgcgattgct aaatcaggat
     2641 tattttccac aaatcccttg gcaacgggtt cttcaaaaat aacggcatcc acttgccctg
     2701 attttaaatc tgtgattaaa ttcccatttt taggcagaga tacgagggaa gaattttgta
     2761 gcaaatcttt cgccatcgtc tcttgaatcg aacctttctg cgctccgacc tttttctgcg
     2821 ccaaatcgtt gacagactga taagtggcta aatcagattt tttgacaatg agtttatttt
     2881 ttgcagtata gtagggagtt gaaaaatcaa acaccttgct ccgttcatct gtcttagaaa
     2941 cacctgatat ggcaaggtcg gcttttcctg attgaacact agccagtaca ttatcaaaac
     3001 tcatgggaga tagttccaat tcgacaccta gttctgttgc gatagccttg gctaattcga
     3061 tatctgaacc cacaatctga tttttcccat caaccacttt ttgatattca aatggagcaa
     3121 aatctggatt gagggctaca accaattttc ctttggactt gatggcttca attccagccg
     3181 attgattgtt actacaagca aatagtaggg ggagcatcac taaaccaaac atcgtcatca
     3241 acaccttctt catcttattc ataacaaagc ctcctttatg tttattcttt tttattgtat
     3301 aaataatact cctatactca tcctttgtca agcctaaatt gaaaaaattt tcaatttgaa
     3361 acaaaaaaaa cctagaaata ctacataaaa tgtcattcct aggcgtattt atgctatttt
     3421 tctctggaaa acatgagtat tcagccagtc aaaaggagct gaatgaactc attttccctc
     3481 gcccaattca atgacacgat gacattgttg ggctacataa gcatcgtggg tcacaataat
     3541 gactgttttc ccttctcgat tcatctctaa gagaaacttc aagaccaaat ctctattttc
     3601 aggatccagc gaacctgtag gttcatcggc taaaatcagc tggctgggtt ttaagatggc
     3661 tctagcaact gcaattcgtt gttgttcgcc cccagacaac tcggagaccc tttgatgcaa
     3721 agtagctgac aaacctactc tctctaaaat ctcttccacc tttttgagct tgtctttctt
     3781 aggcaatttc acatatttca gcgccagcat gagattgtac tcgaccgttt catcatcaat
     3841 cagggcaaaa ttttgaaaca gataagagat atgttcacgg attattgttt gcgacttagc
     3901 agaattaacc gctagatttg tctgaccaaa aatctcatac cgtccgctat aatcaccatc
     3961 tatcaaaccc aataaattta acaaggtcga cttcccacta ccactcttac caacaatagc
     4021 taccaaatcc ccctgatcaa tcctgagaga taagttatcc aaaatcactt ttcccccaat
     4081 ggttttggta atatttttca actcaatcat aagatgcccc ctttcaataa ctctactaga
     4141 cttcttttct ccatcctaga agctaagcct agcacaaata gtatatccag acatgtaaaa
     4201 cctgcaaaca gtagaagtgg taagaacgca tgggcaaaga aaatcaagac tagaagaggg
     4261 aaactatagc ccagcaagag cagaacgagg agaggacggt agcgatcgac cagtttccac
     4321 cccataaact tcttggtaat gatatccctg cgcttcaata agaaagttgt tactagtaag
     4381 aagtaggaaa tcatcatgct aaggagacca aacaaagcaa agagtaggtt aaaattccga
     4441 acagcatctc tataagaatc cactttctct tgttgaatgg cttgaataga tgaaaatttt
     4501 aaataatttc catctgacaa tttctcaact aactctgtaa tctctttttg atgttgaacc
     4561 gtattttcaa ttttaatcgg attatttaag ccagttgttg acagggaggc tttctcatcc
     4621 cacatcatat cagaatcatt gaccaagcta ataattggat tggagagatt ttcctttcgc
     4681 ttatcactat atgggaaaaa tgaccaatct ccttcataat aggcaatctc gacatccatc
     4741 tcctctatcg ttcgtttttg ctgctcttca tacttcatcg aatgaaaggc aattaacttc
     4801 cccaagagct gatttttatc ttcttcacct ttcgtacttg ctggcatcaa aataactttt
     4861 ttaataccgg tatctggtag cttgaatccc ttgctcttta gaaaattgcg attggcatag
     4921 taaacatcca ccgtatctgt taactgatat tgctgaatct gttctgattg gacaaaattt
     4981 tttacaggaa gactgctact ctgcacatag cccgcctgcg ttttttctac caaatcctga
     5041 taaaatcgat agaaataatc tgtagatttc cctgaccctg ctagctcttc ttgccacaga
     5101 ttatcattga gtttgaaggt ttctaaggtc aggtaattac cttgacttac ccactgttgc
     5161 tgataagcaa gttctttgtt ttcttgttct aaacttctgc ccaccccaat cagtaaggcc
     5221 gtcagtaaaa tagttgtccc tattttcatc acataattga agataagacc aaatttgaaa
     5281 gatgaaaaac ctttcagcag agagctgatt gtcatttttt ggattaagag gtaagtcaac
     5341 caactgataa agagataaag ctgcaacagc aaaaaatgag acaaccacag cataggaaac
     5401 aaattttttg gcttataatc aagcaagaaa aacacgccta gattgatcac aagagcccca
     5461 cctaggagga ggtaaaggtt gccttttaca acatcagcta aaacagccct atcttgaaaa
     5521 ccaagtaatt tttgtacccc aactcttttc atctccatca tcggttgata cactgtcact
     5581 aacacaagaa gcaaaatagc caagacaaaa acaatggcag ataaaagcaa atctcgattt
     5641 atgacttcca ctgcactttt gtaggtcggc tctagcaagg tagcctggtc tatcttgaaa
     5701 aaatcgctcc atttctgtac aatcctatcc ttgtccatct cttgtgtaga agttatcgta
     5761 tagcgaccat ttaaactacg agatgtatcc ttgatatagg tttgaaaagt cataagctga
     5821 ataggtttgg cttttagaaa ggtcggaatc gtaccaagtt tattggaaat ttctttatta
     5881 ctatagactc cttcaccatc tgtggtaaaa tcaagagaag aaatcccaaa ctcttggtag
     5941 gggaaggtat ctttatcaaa aacaccagac ttgaccacct catcaccact gtctgttttg
     6001 atgatggaga ctttatactc ctttgataca tcctcaaaaa atcgaagaac agacgctgca
     6061 ggttcgttaa tatctttcaa atacaaatcc aaagaatcta cagtctttcc catttcttga
     6121 atccgaacca cttctcgtgt atagtttaca ttaaaaacaa aaaaagtggt acacagaagc
     6181 aggagtaaca tacagaaatt actgattttt ttcataaaag tgcctccact acagttttcc
     6241 ctctccaaat aggagaggga agaattttac tcaaatccat agaaatattc cattcctgtt
     6301 ggcggaatct tggtgaggga agctctagcc catgcctcag gttttgcata atccttagag
     6361 gttctacccc catgtctaac agttgctgta tgagagcgag tagaatgtaa ataatcagaa
     6421 taaccaaaat ttcctgacca tcctactcca tagttccatt gaccaccatc aacccatact
     6481 gccaaaacac ttgtagaagc aagtatacta cataccatta aagatgcaac accaattttc
     6541 tcatgattta tttctcctat tatcgagagc tattccgtag aaacagctat agtaatttgt
     6601 caacaagtat cgtagtccat tggactcacc ttccttctat ctcatttcat ttttaaacaa
     6661 cgaacttact cttaactaga agaatagttc tcttctgtat caggtctttg aacaaccaga
     6721 gtagtattaa tcacactcta actattactc aagaatcagc ccaataaaca atatggatag
     6781 cgctttcaaa tttttaaact cttatcccat ccttttatct atataataag tgaaaatata
     6841 ataactgtca agtaatcgaa gtgaatttta taaaaaaaat tacaagccaa atttgcaaag
     6901 tttacaataa gccgctaggg caatcgtcta tcagaatgtc cgtttatttg tcaataatcc
     6961 gagaaaatct tgcaacgctt agaagtctat aaaaactatc aacatttata tgacttgcga
     7021 atagcaatcc tgctcaacct ttccacactc tatctataca atcaagataa aaacatgtgt
     7081 aagcaaatct gctacacttt actagaggac gccaagaata agaaaagcta cgataggctg
     7141 gctatctgct atgtccgtat tgggatttgt acagacgatt ctaaacttat ccaaaaaggt
     7201 ttctcactcc tagagctgac cgaggaaact tctatgctgt ctcatctcaa aaaagaagta
     7261 gagatctatt accaagcgaa ggaaagataa aaaagccgag ggagctcctc gaccttttca
     7321 tattatttgt tcgttagttc ttaataccag ccattgttaa gccagaagtt tttagcagca
     7381 gtccatgaac cgtaacgtcc tgcaacgtag gcatctgcta cacgttcttg gttttcagct
     7441 gagtagtcac cgttcaggta tgaatctgtt aattggtaac gtccgatata acgtccattt
     7501 gtagctgtat agctaccacc tgattctttt tgagcgatcc attctttggc ttctgcttca
     7561 gatccgctta cagttgaaac aactgtttca cttactactg gagtttctgc tactggagct
     7621 gaaacagttt catcttgagc ggctggtgcc gcataagtag ctggcgctgg tgttgcaaca
     7681 ggcgctacag ggccatcgat aaccaactct tgaccaacat aaatcaaatg aatgttatca
     7741 atgtggttgt tttctgccaa tttttcaact gttgtgttgt gagtttcagc gatttctgaa
     7801 agtgtatcac cttctttaac agtgtaagtt gatgattctt gagcagatac aaatgatgga
     7861 gcaaatactg caaacaaggc agctactcct gcaagagttg ctttaatctt tttagttatt
     7921 gatttcatat tcgaaaattc tccttctttc tatagttcta tcataccctt taaatattac
     7981 cgtttcttga cacttttatg tagaaatatt acaaaattat tttttatttc cctaaataag
     8041 gtgttttttg tcataaaaga tactattttt atgctatttg aggtattaga aaggttttca
     8101 tccacaatta aagccaagcc cctcattctt tgatataata gagataagaa tttttataag
     8161 gggaaactga tgaaatcact tcgttttcaa tctgtctttg atatcatcgg accagttatg
     8221 attggcccat ctagtagcca taccgctggt gctgttcgta ttgggaagat tgtctcttcc
     8281 atttttgatg atactccgac agaagttgaa ttccaacttt ttaactcatt tgccaagacc
     8341 tatcgtggtc acggaacaga cctagccctt gttgcaggta ttttaggaat ggatacagat
     8401 gatcctgaaa ttccaaatag tctggaaatt gcccacaagc gtggtatcaa gattgtctgg
     8461 accattcaga aagacagcaa tgcccctcac cctaacacca ctaaaattac tgttaaaaat
     8521 gcccacaaga ccatcagcgt gactggtatt tctatcggtg gaggaaatat tcaagtaacc
     8581 gaactcaatg gttttgccgt ctctctcaat atgaatacac cgactatcat catcgttcat
     8641 caagatattc caggtatgat tgcccttgtt acagaggcgc tttcccgcta tggtatcaat
     8701 atcgcccaga tgaatgtcac tcgtgaaaaa gctggtgaaa aagccattat gattatcgaa
     8761 gttgacagtc gcaactgtga tgaggctatc gaagaaattc gaaaaatccc tcatctccac
     8821 aatgtcaatt tctttaaata ggaggaagca tgttttattc tatcaaagaa ttggtcgagc
     8881 aagcagatct ggactttcaa ggaaatgtcg cagaactcat gattacaaca gagtttgaat
     8941 tgaccggtcg cgaacgtgaa gaagtcttcc ttctcatgga acgcaatctg gaagttatga
     9001 aagcctctgt ccaacttggc ctcaatgaaa ataaatctcg tagtggcctg acaggtggag
     9061 atgctgccaa attggaccac tacatcaaaa acgaaaaaac tttatcagat tacacgattc
     9121 tctctgctgc ccgaaatgcc atcgcagtca atgaacacaa tgccaaaatg ggcttggtct
     9181 gtgctactcc taccgcagga agtgccggtt gtctcccttc cgttctcact gctgctattg
     9241 aaaaattaga cctcagccac gagcaacaat tggatttcct ctttgctgct ggtgcctttg
     9301 gactagtcat cgcaaacaat gcctccatct caggtgctga gggtgggtgt caagctgaag
     9361 ttggttcagc ctctgctatg agtgctgccg ccttgactct ggctgcaggt ggaacacctt
     9421 atcaggccag tcaagctatt gcctttgtca ttaaaaatat gctaggcctc atctgtgacc
     9481 ctgttgcagg tttggtcgaa gttccctgtg tcaaacgtaa tgccatggga gctagctttg
     9541 ctttcatcgc agcagacatg gccttggcag gtatcgaatc taaaatccct gtggatgaag
     9601 tgatcgatgc catgtaccaa gtaggagcaa gcatgccaac tgcctttcgt gaaacagctg
     9661 aaggtggact cgctaccacc cctactggtc gtcgcctcca aaaagaaatt ttcggagaat
     9721 aagcttatca aataggagaa accatgacct ctatcacagc gatttttttc gatttggatg
     9781 gaaccctcgt tgatagttct atcgggattc acaatgcctt tacctatacc tttaaagagc
     9841 tgggggtgcc tagccctgat gccaaaacta ttcgtggttt tatgggacca cctctcgaaa
     9901 gtagttttgc gacctgcctg tccaaagacc aaatttctga agccgtgcag atatatcgtt
     9961 cttactataa ggcaaaaggc atctatgaag ctcaactctt tcctcagatt atagacttgc
    10021 ttgaggagtt atcgagcagt tatccactct acatcaccac gacaaagaat acatctactg
    10081 ctcaagacat ggcaaaaaac ttggaaatcc atcatttctt tgatggcatt tatggttcta
    10141 gccctgaagc accccataag gcagatgtca ttcaccaagc cttgcagaca catcaactag
    10201 caccagaaca agccatcatc atcggagata ccaagtttga tatgctggga gctcgagaaa
    10261 caggtattca gaaattggcc gtcacttggg gatttggaga gcaagcagat ctactaaact
    10321 atcaacctga ttatatcgct cacaaaccct tagaggtttt ggcgtatttt caatagcata
    10381 gactgggtaa caattccatt tcagaagaaa atgaagtaat actcaatgaa aatcaaagag
    10441 caaactagga aactagctgc gggctgctct aaacactgtt ttgaggttgc agatagaact
    10501 gacgaagtca gctctaaaca ctgttttgag gttgtagatg gaactgacga agtcagctct
    10561 aaacactgtt ttaaggttgt agatggaact gacgaagtca gctctaaaca ctgttttaag
    10621 gttgtagatg gaactgacga agtcagctct aaacactgtt ttgaggttgt ggatagaact
    10681 gacgaagtca gctctaaaca ctgttttgag gttgtggata gaactgacga agtcagtaac
    10741 catatacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt ataagtctct
    10801 acataataaa acgcatagta ccaaggttaa caaacttgat actatgcgtt tttctttttt
    10861 attcaatgtg ggttgtttga ttagcaaagg cgataatagc ttgcttcaac tcatctccac
    10921 tgagagtgcg gaactctcca atcttttgat tgatggattc taaaggcatg acattaacct
    10981 taccaacgaa aatcttatcc ataacttgat tgtcaacgag ttcggttgat accaagagtt
    11041 cttcgtagag tttttcacct gggcggattc caacttcaac gattggaatt tcactttcag
    11101 tgtggccact tagaagcacc atcttcttgg ccaagtcata aatcttgact ggtttaccca
    11161 tatcaaggat aaagacttcc ccatctttgg cataagcacc agcatggata accagacggc
    11221 tagcttctgg aatggtcata aagtaacggg tcatgcggaa atctgtcacc gttacaggcc
    11281 caccttcagc aatctgacgt tcaaagactg gaatgacact accacggcta ccaagaacat
    11341 tcccaaaacg aactgcacag taggttgatt ggctacgttg gttaaagcca gtgacaatca
    11401 actccgccac gcgcttggtt gctcccataa catttggtgg attaactgcc ttatctgtcg
    11461 aaatcataac catcttagac actttagctt catcaacagc cttagcaaca ttgtaagttc
    11521 cacggatatt gtttttgaag gcttcttttg gattgcgctc catcatagga acatgcttgt
    11581 gggctgccgc atgataaaca atagcaggtt tgtactgctc aaagacttgc aacaaacgat
    11641 catagtcttg aatgtccgca atcacaggta cataatcaat cccttggaac ttacgaatca
    11701 attcatgata aacaaggtag attgagtttt ccccatgacc gagcaagaca atgcgttcag
    11761 gattgaagcg actaacttga cgacagattt cagaaccgat tgaacctcca gctcctgtga
    11821 ctaagatggt cttacctgtc agttctgcac ccagacgcga ttcgtcaaga cggatttcct
    11881 gacgacccaa aaggtccgta atatcaattt tttggaagcc agtacctgct tggtgaaggc
    11941 cctgaacaac agtttcaacc ttaggcatct tgtaacattt gacacccagc ttattacaca
    12001 tctgcaagat acgctcatat tctgacggat ccagcgacgg aatcgcaacg atgacacgct
    12061 cgatttgatg gcgtttggct aattcaggca gattgtcata agagcccaaa acaggaatac
    12121 caccaagttt ttgacccttt ttcttagaat ccttatccaa aataccgacc agttctaatt
    12181 cactggttgg atgttggtaa ctatccataa aaagagcccc accatcaccg gcaccaatca
    12241 agaaggttcg acggtgttct ccatcaccac tacctttttt gcgtctggag tagattaact
    12301 gccaagtaat ccgtggcaat aaaatcaaga aggtactcaa caagataaag agaatgatga
    12361 aacggatgga gaagagtggc aagaaggcat aacagatact atatgacaag acactgctag
    12421 cagtcacacc aaaaaagatt ttcatgaaat ccgtaatctt gctgtaacga ctaatgctcg
    12481 cgttcaaccc ccaaaaacca atcatcaatt gatagaacag gaaggccaaa ctcgtataga
    12541 taatgtagtc aacaggtgct ggattaatca gcccataaaa taaaatataa gatacaatga
    12601 tggaaaccac catactgaaa atatcaaata ttccccagaa aacctgcttt tgttgtttat
    12661 ttaaaatttc caccagatca atcacataat ctgttagttt tttattcata gaaatctact
    12721 cctccttaaa agagttttac tatattgtta ttatagcata ttttgattta tttggcttat
    12781 tttatccaaa taaattattg ttcccttgta ctccttcttc catttaaatc ctctaattaa
    12841 acctacaatc gtcccaaagc cataagcaaa gtgaatggaa aataaaagaa agggcatcac
    12901 aattagaaat ccatttttat gttttaataa agtcagcaaa gtgagtagtg acaaaagtag
    12961 aaaataggca cctaatagta aagttatgaa tacgaatgtg atcggtaaca atgctagact
    13021 aaacacaaga ctcaaaacaa ataaacaagg aacatagtga aataatgata aacacttaaa
    13081 ctgaacatga cttgtcaagc caatccacaa accatttgaa tacttttgat gcagcatttt
    13141 cttgaatgtt ggtcgaatat actgataaga tagaatactt gggctatagc ggattttata
    13201 accatgttct cgaattctat aatgaatatc attatcttca gttcggccaa gttgctcatt
    13261 tactaaacca accttctgga aaacctctcg tttatacatt ccatgaaaaa tagaagaaac
    13321 atatctatcc tcagaactat ttcgataatt ggcaatgcta ctgccaaaca tattttcctc
    13381 aacaagatgc aaggtctctg cccattttcc ttttccttcg acaatcgtcg gtctaggccc
    13441 cccacagaca aattcacctt gttgaataat agccacattg ttcattacaa aagtctcagt
    13501 aacttttgaa tgagcatcaa tttttaaaat aaggtcccct acagaatgtt taactcccag
    13561 gttaaaacca ctagcttgat ttttcttagg attgttatac aatctaattg agttaaactc
    13621 tgtatcttcc tttataaatt gctgaatgat agctgtggtc ccatctgtgg acatagcatt
    13681 tataaataga atttcaatat tctctttagg ataagtttga ttttttaagt cttcaattag
    13741 accaggcaga tatttttctt cattgtatgc actgattaca atggatacga gaagactttc
    13801 aacattttga gtcactacta ctctcctgaa tttttccttc caccattcta tcataatttt
    13861 ccagactttc ccatttttat cttgaaagcc agaaacctta cttgacatta tagtgaaaaa
    13921 gccttaaaat aagctgttat taaaatcagc tagaagaggt attatatgaa aaagcaatca
    13981 ctcttttttg ttccaggtat tatcctgatt ggtgtttcct tgcgaactcc ttttactgtt
    14041 ttacccatta ttttgggaaa tatttcgcaa ggtctagagg tagaagttag ttcgcttggt
    14101 gtcttgacca gcctgcctct ccttatgttt accctctttt caccattttc tacccaactg
    14161 gctcagaaaa tcggcttgga gcatctcttc acctacagcc tcttcttctt gaccatcggc
    14221 tcacttattc gactaatcaa tctgcccctg ctctatctag gaaccttgat ggttggggca
    14281 agtgtcgcag tcatcaatgt cctgcttcct agtcttatcc aagccaatca accaaagaaa
    14341 attggttttc tgaccacctt atatgtaacg tctatgggga ttgcaacggc tctggcttcc
    14401 tatctagctg tgcccattac acaagccagt tcttggaaag gacttatcct cctcctcacg
    14461 ttactctgtc tagcaacttt tttggtctgg ctcccaaatc accgctataa tcatagacta
    14521 gctccacaaa ccaaacaaaa aagtcaaata aaggtcatgc gtaataaaca ggtttgggca
    14581 attattatct tttcaggttt tcaatccttg atcttttaca ccgtcatgac ctggttacct
    14641 accatgtcta tccatgcagg tctatccagt cacgaagctg gcttgctgac ttctatctta
    14701 tctctgatta gcattccttt ttcaatgacc atcccaagcc tgacaaccag tttatctact
    14761 cgcaaccgtc agctcatgct cactctggtt tcactagctg gtgtggtcgg catttccatg
    14821 ctctttttcc caatcaataa tttcatttac tggcttgcca tccatctcct catcggaacc
    14881 gcaaccagtg ccctcttccc ttatctcatg gtcaactttt cactcaagac aagcgcccct
    14941 gaaaagacag cccaattgtc cggcctatct caaacaggag gctatatcct agcagccttt
    15001 gggccaaccc tctttggtta cagttttgac ctgttccact cttgggtacc atctgtagct
    15061 gccctcttgc tcatcgatat cctgatgact gtggccctct ttacagtgga cagagcggat
    15121 aagatccttt aaacttctag ttttagctag aagtttttta tatataaaaa ttttacacat
    15181 ttctcttgac agggatttct tttagatgta caatatatgt gtagaaaaat tatatataaa
    15241 aatcttacac attagaaaag gaggtttccc atgtactttc caacatcctc tgccttgatt
    15301 gaatttctca tcttggctgt actggagcag ggtgattctt atggttatga gattagccaa
    15361 accattaagc tgatcgctaa tatcaaagaa tccacactct atcccattct caaaaaattg
    15421 gaaggcaata gctttctgac aacctattct agagagttcc aaggtcgcat gcgcaaatac
    15481 tactccttga caaacggtgg tatagagcag ctcttgaccc taaaagatga atggacactc
    15541 tatacagaca ccatcaatgg catcatagaa gggagtatcc gccatgacaa gaactgaata
    15601 cctgactcag ctagaactct atctcaagaa actacctgaa gctgaccgta tcgaagccat
    15661 ggactatttc agagagctct ttgacgatgc tggagtcgaa ggagaagaag aactcatcgc
    15721 tagtttggga actcccaaag aagcggccca cgaagttcta tccaatcttc tcgataaaaa
    15781 aatcaatgaa gcacccgctc aaaaaaataa ccgacaaatt ttacatatcg ccttgttagc
    15841 cctccttgca gcacctatcg gcattcctct gggaatcgcc atcctcgtga ccctgttcgc
    15901 aatccttgta gccgctttga ctgtcattct ggctttcttt gcagtttcca tactgggtat
    15961 catcggcgga ttcctatttt tagttgaaag tttcactgtc ctcgcccaag ccaaatcagc
    16021 ctttatcttg atttttggtt ctggtttact ggctatcggt gcttcttcgc tagttttact
    16081 tggcatttcc tatgtaactc gcttcttcgg tctactcatt gttcgtctgg tacaatttgt
    16141 tcttaaaaaa ggaaagagag gtaatcagca tgcgtaaatg gacaaaagga tttctcatct
    16201 ttggtgtggt gactaccgtt atcggcttta tcctgctttt tgtaggtatc caatctgacg
    16261 ggattaagag cctactttcc atgtccaaag aacctgtcta tgatagccgt acggaaaagc
    16321 taacctttgg caaggaagtc gaaaacctag aaattactct ccaccaacac acgctcacca
    16381 tcacagactc tttcgatgat caaatccaca tttcttacca tccatctctt tctgctcacc
    16441 atgatcttat caccaatcag aacgatagaa ctctgagtct cactgataag aaactgtctg
    16501 aaactccgtt tctctcttct ggaattggtg ggattcttca tatcgcaagt agctactcta
    16561 gtcgttttga agaagttatt ctccgactac caaaagggag aactctaaaa gggatcaaca
    16621 tctcagccaa tcgcggacaa accaccatca taaatgctag ccttgaaaat gcgaccctca
    16681 atacaaacag ctatatcctc cgaattgaag gaagtcgtat caaaaacagt aaactcacaa
    16741 cgcccaatat cgttaatatc tttgatacag ttcttacaga tagtcagcta gagtcaacag
    16801 ataatcactt ccacgctgaa aatatccaag tccatggtaa ggttgaactg actgccaaag
    16861 attatctcag aatcatccta gaccagaaag aaagccaacg aattaactgg gacatctcaa
    16921 gcaactatgg ttctatcttc caattcacaa gagaaaagcc tgaatcaaga ggtacggaat
    16981 taagcaaccc ttacaaaact gaaaaaaccg atgtcaagga tcaactcatt gcgagatctg
    17041 atgataatat tgatctaata tccacaccaa gcagacgttg acaaaaacgc ttacatctgc
    17101 tactatggaa gcatatttat ctaaccaaaa ggaggttcta ccatgaaaca agaatggttt
    17161 gaaagtaatg attttgtaaa aacaacaagc aagaacaagc ctgaagagca agctcaagag
    17221 gttgcagaca aggctgaaga aacgatagcc gatctcgata caccaattga aaaaaatact
    17281 cagttagagg aggaagtccc tcaagctgaa gtcgaattgg aaagccagca agaagagaaa
    17341 attgaaactc ctgaagtcgg tgaagcgaga acagaaatag aagaaaagaa ggcatctaat
    17401 tctactgaag aagagtcaga cctttctaaa gaaacagaaa aagtcactat agctgaagag
    17461 agccaagaag ctcttcctca gcaaaaagca accacgaaag agccacttct tatcagtaaa
    17521 tctttagaaa gtccttatat ccccgaccaa gctccaaaat ctagggataa atggaaagag
    17581 caagtgcttg atttttggtc ttggctagtg gaagcgatca aatctcctac aagtaagttt
    17641 gaaacaagta tcacacacag ttacacagcc tttctcttgc tcattctgtt ttctgcatct
    17701 tcctttttct ttagtatcta tcacatcaaa catgcttact atggacatat agcaagcatt
    17761 aacagtcgct tccctgagca gctagctcct ttaactcttt tttctatcat ctctatccta
    17821 gtagcgacaa cactcttctt cttttcattc ctcttgggta gtttcgttgt gagacgattt
    17881 atccaccagg aaaaggactg gacgctagac aaggttctcc aacaatatag tcaactcttg
    17941 gcaattccaa tcttcctcac tgctattgct agtttctttg ctttctttga tagcctacga
    18001 tttacagccc tcttgtgtgt gattagcatt ggaatcattc tgcttgccag tctccatatc
    18061 attacaagac caagtcaagc aagtgaaacc gactccttct atcaattatt cttgtctgtc
    18121 cttgtgaacg gagttattat cctcctcttc tttgtagctg aagtggcact gattggagat
    18181 tatcttcgta tcttggcctt tctttaaaat tcatactctt cgaaaatcaa attcaaacca
    18241 cgtcagcttc gccttaccgt actcaagtac agcctgcggc tagcttccta gtttgctctt
    18301 tgattttcat tgagtagcaa tcctgtcatc cttggcagga ttttttctat gtcaaaaaag
    18361 caagtcgatt gacctgcttc tgctttactt ttcttgtgct aatgttttaa aatcttgtcc
    18421 taggatgggt tgtatttcta tttgattggc gtctagttgg tggtaaaaag atgggggtaa
    18481 tacctctaag aattttgcat agtccaagcg agctatggat tcatagtctt ctggtttaga
    18541 gccgtctcct gtgatttgaa ccaagtcaat ctcccactgg acttccttat ccaccaattg
    18601 ctcaatatag gctgcaggaa caaacggttc tctcggtaaa actgtcttga ctccttgagc
    18661 tagatggtaa acgccatgca cttttccttc tccatcctga tagaaggaaa ctctcgcaaa
    18721 gtaggcatct gtctcttgaa ccgcacgcac acgcgcttca aactgagcca agccatctgc
    18781 ctctaaaaag cttttcaagt tctcacgact aaagaaaata ggattaaaaa ttccttggca
    18841 aatcgtaaaa cgagctacag ggtctgctag ataggcttga atacttgctt ggaaataagc
    18901 ttcaaaatca aaaccatcta gcccttcaat atcagtccct gtataagcaa gcaaagcatc
    18961 taaaaatgac ttgataatct gccagtctgt ctttgttagt aggtcaggaa gatcgacacg
    19021 gtaagccttt tgaccatcag cataactgac cttaaaaaga aattgtgatt gccccactat
    19081 cgcacactca atatactcga gacgattaag aggctgacgg agatagacta catcatagct
    19141 atgtgactcc aaaccgtcta gcaaggccaa gatcgacttg gcattcaaaa tctcttgttc
    19201 tcctaaaatg ctctgtttat ttggaataaa aaatgttttt gccataactg gactcctttg
    19261 aaatcgttta catacagtat accttatttt tctgaaagat acagaaacaa actttatact
    19321 cttcgaaaat ctcttcaaac cgcgtcagct tcgccttgcc gtagatatat gtaactgact
    19381 tcgtcagtct tatctacaac ctcaaagcag tgctttgagc agcctgcagc tagcttccta
    19441 gtttgctctt tgattttcat tgagtattag atttttgagt acaaagcata gaaaaacagc
    19501 ccctgaggac tgtttgatct tatacagtag ctgcttgatc caagctttca ccgatagcgg
    19561 ctaggcgctc gatcacttca gcttgtgtca attcattttt tgaaacatag cggttacgtg
    19621 ggtgaacacg gcactcgtgt gagcatccac gaaggtactt gtcttcattt tcttccgatg
    19681 tcaagatacg acggttacag aatggatttc cacagttgac ataacgttca catggtgttc
    19741 catcaaacca gtctttccct acgatagttg ggttgacatg gttgacatca acggcaatac
    19801 gctcgtcaaa gacgtacatt ttcccatccc aaagctcacc ttgaacttct gggtctttac
    19861 cgtaagttgc gattcctccg tgcaattggc cgacatcttt gtagccttca cggaccatcc
    19921 agcctgagaa tttctcacag cgaacgccac ctgtacagta aaccacgaca cgcttgtcca
    19981 tgaatttttc cttgttatca cggacccatt gtggtaactc acggaagttg cgaatatctg
    20041 ggcgaatagc cccacggaaa tgtcctagat cgtactcata atcgttacgt gtgtcaagga
    20101 caacggtatc tttatcaaga agcgcttctt tgaactcttt tggagacaag taagcacctg
    20161 ttgtttcaag tgggttgatg tcattgtcaa agtcgttgtc ttccaaacca aggtggacaa
    20221 tttctttctt gtagcgaaca aacatcttct tgaaggcttg ttcattttct tcgtcaatct
    20281 tgaaccagag atcttccata cctgggaggc tgtgaacgta gtccatgtat ttttgagttg
    20341 tttcatagtc acctgaaact gttccgttaa ttccctcatc agcgactagg atacggcctt
    20401 taaggccgat tgatttacag aaagccaagt ggtctgcagc aaattgctct gcattttcaa
    20461 ttggagtata aaggtagtaa agtaagacac gaatatcttt tgccataaga tttgttctct
    20521 tttctattct taaattttct aaatttttta tttatctaca ctagtatacc tgcttgagaa
    20581 aacgaatgca atttatttga ctggaaattg tagagggttc tcgaaatttc ctgaatggtt
    20641 aaaataagga caagagaaaa catggatatc tatatccttg tgccaaaaaa accactgccc
    20701 tccccagacc aacctgagga aagcagtgat tcttatttta ggagttagga atgaatacac
    20761 gaaatcaatt tagctgatta ttttttgttt ttcaagaatt catcgtattg tttttgcatt
    20821 tcgttcaata ctttttcgta ggcaccttca gatttcaatt tttccatcaa ttctggaatc
    20881 gctttatctg ggtctacagt accagtgttg atagctgtat caaattgttg cattgtgtta
    20941 gcaatagctg agatttcaga tttcacattg tcagtattaa agataaatcc aagcgctgga
    21001 gattctttag cttctgccaa ttctttctta gaattttcga tttgttggtc tgtaacgttt
    21061 tcgttgatgt aaaggatcca gttgttacca gtgttccatc cacccatgtg agtgtttcct
    21121 ttgtagccat caagaacgcg aacacggttt tctttacctt caattttttc ccagttcttg
    21181 ccttctggac cgtaaacaag accgttcaag agttctgggt tggtattcaa gaggttcaag
    21241 atttccattg atttttcttt gttcttagag ttgtttgaga tgacaaagtt agcaacttgt
    21301 gttgtttggt ttttcttgat gaagttagta attggtttga tttggatatc tttgttggca
    21361 acacgtgaaa gcaagctgtt accgtagtca gctggtccta ctgtttcttc acgaacgaac
    21421 caagtatctt gttgaaggtc aaaggaagta tcgcttgttg cgacgtcttt tggaatgtag
    21481 ccagcttcat agaatttgtg aagagtcttc aagtgttctt tgaaacgagg cacttcgtaa
    21541 cggtttacaa ctttagtagt atcgccttca aggtcgataa cgaatggaag accgtttgct
    21601 actgggtagt caaagttatc agatgggatg aaaactttac caatagcaaa tggtactacg
    21661 tctggagctt tttctttaat ttgtttcaag actggctcaa gagtttcgta agaagtaaca
    21721 cctgaaatat cgataccata tttagcaagg agagttccgt tgaaggcaaa gttttgagat
    21781 gacgcaacgt tggctgcaac tggtacagca taaatcttac catttacagt attacccttg
    21841 atataagctg ggtcaagtgc cttgtaaagg tctttacctt cttttttgta caattctgtc
    21901 aagtcagcat aagcaccttt ttgagcattt acaatatagt tatctgcaaa ggcgatatca
    21961 tagttttcac cagatgatgt gataactgac attttcttac catagtcacc ccagccaagg
    22021 tattggatat ccaatttagc accaactttt tcttcgatga ttttgttggc atttgctaac
    22081 aattcatcca agttatctgg tttgtcaccg atttggtaca ttttgataac aggtttgtca
    22141 cctgaatcag cagctttttt actgttacct gtcaagttgc cacaagcagc aagacctgca
    22201 gccaaagcga ctacactagc agatgcaaaa gcatattttt tccagttttt catgataaaa
    22261 actccttttt ttatttttaa acttataaac aatgtaatga tcttatactc aatgaaaatc
    22321 aaagagcaaa ctagaaaact agccgcaggc tgtacttgag tacggcaagg cgacgttgac
    22381 gcggtttgaa tttgattttc gaagagtatt aacttcacac aagggaagtt gggaactgag
    22441 aaatgttctt tttcaataag cactattctt tcacaccacc gatagtcaaa ccttttacaa
    22501 agtagcgttg gaagaatgga tacaaaatcg cgattggaag ggttgctacc acaaccatgg
    22561 ccatacgacc tgtttctttc ggtagagcaa ctcccagttg accagtcaag ccgaccgctt
    22621 tggcaatgta gtccatattt tgttggattt gcatgagcaa atattgcaat ggatacaagt
    22681 tatcactctt gatgtaaaga agggcgttga accagtcatt ccagaaacca agagctgtca
    22741 aaagcgtgat ggttgcgata cctggtagtg acaatggcaa acagatttgg aagaaaatcc
    22801 gagcctcact ggcaccatcg atacgagccg attcgagaat ggcttctgga atggtcttct
    22861 tgaaaaaaga acgcatcaag atgatattga atggtgagag aagcattgga acaatcaagg
    22921 cccaaacagt gtcaccaagc tgaagtacac gggtcaccat gatataacct ggtaccaaac
    22981 cagcgttgaa caacatactg agaaggacga agatggtaaa aaatctgcga tacttaaagg
    23041 ttgtccgtga aatagcgtag gcataggttg ttgtgataaa gacatttgtc aatgtcccaa
    23101 ctacggttac aaagacagag atgaagaggg cttgtaggat tttatcctta aactgtgcca
    23161 aaaactcaaa accgtctaag ccaaattggg atgggaagaa gctatagccg tattggagga
    23221 ggcttttctc gtctgtcact gaaataatga taacgaatac aaaaggtagg atacaagaga
    23281 gggcaatcaa acccgaaatg atactgaaga agatatctgc tttcttactg aaggagtgaa
    23341 tgccgacatt atcaattttt tcttttttaa ttttcttttt tgccatattc tcctcctttc
    23401 tagaacaaag ctgagtttgg atcgactcgt cttgcaagca agtttgatag gataaccaga
    23461 atcaaaccaa caacggattg gtaaagaccg gctgctgcag ccataccgat atctgctgtc
    23521 tgagtcaaac cattaaagac atatacgtcc aaaacgttgg ttacattgta aagctgacca
    23581 gcattgtgtg ggatttgata gaagagaccg aaatctgcgc ggaagatatt tccgactgca
    23641 aggatggtca atacagttac aagcggagtc aactgaggaa tggttacgtt gcgaatacgt
    23701 tgccacttgc tagctccgtc cactgtcgct gcttcgtagt aggttggatc aattcccatg
    23761 atcgtcgcat agtacatgac actgctatat ccaaagcctt tccaaatacc taggaaaagt
    23821 aggagatagg gccagatgcc caggtcagcg tagaaattga cttctttgag accaagactt
    23881 tccaatagat gattgaacac ccctttatca atatttagga aggcatctgt aaagaaacta
    23941 atgataaccc aagacaagaa gtaagggaac aacatagaag tttgaaaaat cttcaccatt
    24001 ctcttagaac ggagctcgct gaggataatg gcaatcccta cagatacaac taaacctaga
    24061 aagataaagc caagattgta gaggacagta tttcgtgtga taataaaggc gtctcttgaa
    24121 ctaaataaga atctgaaatt atcgagtccg acccatttac tatttatgat actatctatg
    24181 aaaccattac tggtcatgtg gtagtctttg aaggcaacca cgttcccaaa tactggaatg
    24241 taaaagaata gaatcaacca gagtgcccct ggcaaaacca tcaagagaaa gatccagttg
    24301 tctctcaatg tttttgaaaa ctttttcata atttcctccc tttttatttt gatatccatc
    24361 taaaaattct tttttagact tttgataacg attacattat tagtatactc ctatttgcag
    24421 gttaggttaa actcctaatt atagaaaaaa ctccacaaat tatgtagcag atttaaaact
    24481 ttatcaccac tatcaaacaa atgtcctaaa tcaattgttt attttatctc tattagccca
    24541 gtgatggcgt cactctgtta taagcatcca acaacggggt atactgaaaa atctccagac
    24601 tagggaactc agcgatagtt cctaatctgg agatttttaa tatgttatta ggcgtttgct
    24661 ttcaacttag caataacctc tttaagatta tcaatcaact ctgcttcagt atgctcagag
    24721 cctttttcat ctgccaagaa caaaactgct ttttgaagtt cttcttgaga gttttcaagg
    24781 acatccttat ctgctgtttc tttgcccgct gtttgtcctc catccttagt tgctgactgg
    24841 ctttccttaa tggactctag ggaagcaatg gcatctttga ctgtttgcaa gatatcacgt
    24901 aaaccttgct ctgtcaaact atcatctgca aaagctttct tagcctctgc caaaaccaga
    24961 cgtgctgaat ctgtggtagg attcgataca cctgtcaatg atctcaaaag attttctaag
    25021 gtttgagtct gcttactaat actagactaa aataaaaaag cattatataa cagtgatatg
    25081 aaatcaacta aagaagaaat ccaaaccatc aaaacacttt taaaagactc tcgtacagct
    25141 aaatatcata aacgccttca aatcgttcta tagtaaaatg aaacaagaac aggacaaatc
    25201 gatcaggaca gtcaaatcga tttctaacaa tgttttagaa gcagaggtgt actattctag
    25261 tttcaatcca ttatatttcg tctgatgggc aaatcttata aagagattat agagctttta
    25321 tagtagtttg aaataagatg tgaacaactc tatcaggaaa gtcaaattaa tttatagaaa
    25381 tattttagca gccaaggtgt actgttatag attcaataca ctatacttgg tggtttagct
    25441 ctcctgtttt ctcttttagc tttaaccagc cataaatggt attacgtgag atttggaaaa
    25501 cgtgtgatgc ttctgttata ctacctgttc gctcacaata agagagaact tttttacgaa
    25561 aatctattga atatgccata aaaggattat accacattgt gtactatttt tggttcattt
    25621 tactatatca ctttggacta tatcggtcta gttatgtctc aacgattata gctggatact
    25681 aagagaaatc aaaaaagcac tctaggatag aggcctaaag tgcttagttt caaggcttta
    25741 cagcctatca tatttaataa aatattacaa cattttgttg tatcgctttt ttaagtattc
    25801 agcaagtagc tttattactt cttaatgctt gataataggg tgatggggag ttttcacttt
    25861 tcgtttgaac gttttggagt ttctccctta ctccacaaat cactgaacat gataaacgag
    25921 ttcagcaggc aagaaactag cactatttaa aagtgctttt ttgtttctat ttaataggaa
    25981 gctattgcac atcttttaat atttgtttta ttagtttgca tgaagcattc taaatactct
    26041 tcatcttcta atctaaaatc taacaatagc ataaatttaa tttcgtatct gttctgttat
    26101 attggaactc tatatgtacc tgttctttaa tcttcaaagt ttagcttaga ttcttttttg
    26161 attgtaagtt tagtatttta aaactgtgtt tttccttctt ctttaataat taatcaaata
    26221 tagtaaaaac ttatcctagc gctaacataa agttgttatt ataaatctct ttttatttta
    26281 aaatcatagt aaca
//
LOCUS       DAVKAU010000023        26109 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVKAU010000023 DAVKAU010000000
VERSION     DAVKAU010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.023"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            537..1700
                     /locus_tag="VWX48_001166"
     CDS             537..1700
                     /locus_tag="VWX48_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU9171796.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1697..2374
                     /locus_tag="VWX48_001167"
     CDS             1697..2374
                     /locus_tag="VWX48_001167"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU9171797.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2364..3218
                     /locus_tag="VWX48_001168"
     CDS             2364..3218
                     /locus_tag="VWX48_001168"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU9171798.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3237..4304
                     /locus_tag="VWX48_001169"
     CDS             3237..4304
                     /locus_tag="VWX48_001169"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU9171799.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4314..5480
                     /gene="aroC"
                     /locus_tag="VWX48_001170"
     CDS             4314..5480
                     /gene="aroC"
                     /locus_tag="VWX48_001170"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU9171800.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMYVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5490..6593
                     /locus_tag="VWX48_001171"
     CDS             5490..6593
                     /locus_tag="VWX48_001171"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU9171801.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            6604..6942
                     /locus_tag="VWX48_001172"
     CDS             6604..6942
                     /locus_tag="VWX48_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU9171802.1"
                     /translation="MSNIYDSANDLSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            7034..8317
                     /gene="aroA"
                     /locus_tag="VWX48_001173"
     CDS             7034..8317
                     /gene="aroA"
                     /locus_tag="VWX48_001173"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU9171803.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8310..8786
                     /locus_tag="VWX48_001174"
     CDS             8310..8786
                     /locus_tag="VWX48_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU9171804.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQRDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8783..9631
                     /gene="pheA"
                     /locus_tag="VWX48_001175"
     CDS             8783..9631
                     /gene="pheA"
                     /locus_tag="VWX48_001175"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9171805.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9628..10902
                     /gene="psr"
                     /locus_tag="VWX48_001176"
     CDS             9628..10902
                     /gene="psr"
                     /locus_tag="VWX48_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU9171806.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11181..12026
                     /locus_tag="VWX48_001177"
     CDS             11181..12026
                     /locus_tag="VWX48_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9171807.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            12016..13119
                     /locus_tag="VWX48_001178"
     CDS             12016..13119
                     /locus_tag="VWX48_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9171808.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            13121..14107
                     /locus_tag="VWX48_001179"
     CDS             13121..14107
                     /locus_tag="VWX48_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9171809.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            14123..15556
                     /locus_tag="VWX48_001180"
     CDS             14123..15556
                     /locus_tag="VWX48_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU9171810.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMI
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15585..16619
                     /locus_tag="VWX48_001181"
     CDS             15585..16619
                     /locus_tag="VWX48_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9171811.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16819..17556
                     /gene="mecA"
                     /locus_tag="VWX48_001182"
     CDS             16819..17556
                     /gene="mecA"
                     /locus_tag="VWX48_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU9171812.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17707..18993
                     /locus_tag="VWX48_001183"
     CDS             17707..18993
                     /locus_tag="VWX48_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU9171813.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVAFYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18995..19864
                     /locus_tag="VWX48_001184"
     CDS             18995..19864
                     /locus_tag="VWX48_001184"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU9171814.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            20114..21052
                     /gene="msrB"
                     /locus_tag="VWX48_001185"
     CDS             20114..21052
                     /gene="msrB"
                     /locus_tag="VWX48_001185"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9171815.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            21110..22834
                     /locus_tag="VWX48_001186"
     CDS             21110..22834
                     /locus_tag="VWX48_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171816.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLIPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVKLFKGTIRSNLTLGLNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            22836..24584
                     /locus_tag="VWX48_001187"
     CDS             22836..24584
                     /locus_tag="VWX48_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171817.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQFPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24841..26100
                     /locus_tag="VWX48_001188"
     CDS             24841..26100
                     /locus_tag="VWX48_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU9171818.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIELLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVVVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLIVEL"
BASE COUNT         7697 a         4871 c         5882 g         7659 t
ORIGIN      
        1 ttatagttta tttattggga tatttttcaa tttcaaaaac gttaattcct ataatgtgtg
       61 tgatccaagt atttttgata gaacatatat ttagagttcg aaatagaatg atacagatag
      121 gtgaaattat aattattgtt gcttctataa tattatttat tgatagtata ttgagtttgt
      181 aacaaaaggc ttctctataa aatcaaattt tccagatacc tattgaagta gatttatttc
      241 ttcatctttc ttctactacc tttgtcacta aatttgacag acacatattg ctgattcaac
      301 ctctctacct ataatctcac agttaacctg aggctagttt catagtttgc tatttgattt
      361 tcgttgataa aaagaaatgc tcctccaaga cggaagagca ttttttattg tgattcttac
      421 acatttactt cctagttttg caggaagtct agtataccat tttttaaaag aagagtaaaa
      481 aagcaagggt agtttctttt ttgagaattg tctaaaagtt tgatataatg gtagttatga
      541 atagaataag agtcagcaaa agggttgaaa agaagcttgc taaggggcta gttttactag
      601 aagccagtga tcttgagaat gtcaatctta aggatcagga agtagaggtg cagggtcagg
      661 aaggaaactt tcttgggact gcctaccttt ctcagcaaaa caagggcttg ggctggtttg
      721 tcagcaaaga caaggtggcc ttcaatcaaa ctttctttga aacgttgttt agaaaagcca
      781 aagaaaagag aaacgcctac tatcaagatg atttgacaac tgcctttcgt ctctttaatc
      841 aagagggaga tggctttggg ggtctgacag tggaccttta tggcgactac gccgtctttt
      901 cttggtataa ctcttatgtt tatcagattc gtcagactat atcagaagcc tttagacagg
      961 ttttccctga ggttttaggg gcttatgaga aaatccgctt taagggtttt gactatgaat
     1021 ctgcccatgt ttatggtcaa gaagcacctg actttttcac tgttttagaa aatggtgtcc
     1081 tgtatcaagt ctttatgaat gatggcttga tgacaggaat tttcctagac cagcatgagg
     1141 ttcgcggtag tttagttgac ggcttggcta tgggtaaatc cttgctcaat atgttttcct
     1201 acacagcggc tttttcagta gctgcggcca tgggaggagc tagccagaca acttctgttg
     1261 atctagccaa acgttcacga gaattgtctc aagcgcattt tcaggcaaat gggctcagca
     1321 cagacgagca tcgttttata gtcatggatg tctttgagta tttcaaatat gccaaacgca
     1381 aagacttgac ctacgatgtg attgtcctag atccgcctag ctttgctcgg aataaaaaac
     1441 aaactttctc tgtggccaag gattatcaca agttgatttc ccagagtctt gagattttaa
     1501 atccgggagg gattatcatt gccagtacta atgctgccaa tgtttcccgt cagaaattta
     1561 cagaacaaat tgataaaggc tttgcaggaa gaagttacca gattttaaac aaatatggtc
     1621 ttccagcaga ttttgcctat aataaaaaag atgaaagtag taattacctc aaggtgatta
     1681 gtatgaaggt tagtaaatga aattaatcgt ttcagtaatg ccaagaagtt tagaggaggc
     1741 tcaggctctg gatgccacga ggtacctgga tgccgacatc attgaatggc gtgccgacta
     1801 tctgcctaaa gaagcgattt tgcaggtagc tccagccatt tttgaaaaat tcgcaggccg
     1861 tgagttggtt ttcacgctac gaactcgctc cgaaggtgga gaaatcgacc tttctccaga
     1921 agagtatatc catctaatca aggaagttgc gcaattctat caaccagact atattgattt
     1981 tgagtactat agctacaagg atgtttttga ggaaatgctg gacttcccaa atcttgtttt
     2041 gagttaccat aatttccaag aaacacctga gaacatgatg gaaatcttgt cagagttgac
     2101 gatcctaaat ccaaaacttg ttaaggttgc ggtgatggct cacacggagc aggatgtctt
     2161 agacttgatg aactatacac gaggctttaa aaccctcaat cctgaacagg aatatgtgac
     2221 catttctatg ggtaaggtgg gcaaggtctc tcgtatcact gcggatgtga ctggttcgag
     2281 ttggtctttt gccagtctgg atgaggttag tgcccctggg cagatttctc tagctagcat
     2341 gaaaaaaatc agggagattt tggatgaagc ttgatggcta tacacgttta gctgcagttg
     2401 ttgccaatcc tattaagcat tctatttctc ccttcatcca caatagagcc tttgaggcga
     2461 cagctaccaa cggtgcttat gtggcttggg agattgaagc gagtgacttg gtagaaacag
     2521 tggccaatat tcgtcgctac cagatgtttg gcatcaatct gtccatgccc tataaggagc
     2581 aggtgattcc ttatttggat aagctgagcg atgaagcgcg cttgattggt gcggttaata
     2641 cggttgtcaa tgagaatggc aatttaattg gatataatac agatggcaag ggatttttta
     2701 agtgcttgcc ttcttttaca atttcaggta aaaagatgac cctgctgggt gcaggtggtg
     2761 cggctaaatc aatcttggca caggctattt tggatggcgt cagtcagatt tcggtctttg
     2821 ttcgttccgt ttctatggaa aaaacaagac cttacctaga caagttacag gagcagacag
     2881 gctttaaagt ggatttgtgt gctttagaat atgtttctga actgcaagca aggattgccg
     2941 agtcggattt gctagttaat gccaccagtg tgggcatgga tggccaattc tctcctgttc
     3001 ctgaaaacat agtcttacca gaaactctct tagttgcaga tatcatatac caaccctttg
     3061 aaacaccgtt tttgaaatgg gctagaagtc agggcaatcc agcagtcaat ggtctgggaa
     3121 tgttgctcta tcaagctgca gaagcttttc aactgtggac aggcaaggaa atgccgacag
     3181 aagagatttg gcagtcttta acagaaaaat accaataaag aaagggagac tctcctatga
     3241 aaatcagaat cgatattcct catcatcctt atgatattca gattgaaaaa ggttgtatgg
     3301 cccaggctgg tcagtggttg cgagaactct ggcaaccgca aaaggtagtc attgtgacag
     3361 ataaccatgt agcctctctc tatgcagaga aggtcaagct cagcctagaa gatgctggtt
     3421 ttcaggtagc tgtttttgat ttcttagaag gtgaagaaag aaagaattta actactgttc
     3481 agaaagtcta tgaatttcta gtcaagcaag gtctgactcg tagcgatgga atcgttgctc
     3541 ttggtggtgg cgttgttggg gacctggctg gatttgtagc ctctacctat atgcggggta
     3601 ttcactttgt tcagattccg actagtttga cagctcaggt tgattcttct atcggtggaa
     3661 agacaggtgt taacacacca tttgctaaaa atatggtggg gacctttgcc caaccagatg
     3721 gggttttgat tgatccactt gttcttgaaa ccctcggaaa aagagagttg attgaaggga
     3781 tgggtgaagt tatcaagtat ggcttgattg aggatccaga actgtgggct ctcttgacgg
     3841 gactgaatgg ttctgttgag agtattttgg aacatgcaga gaccttgatt gaacattctt
     3901 gtcaggtgaa gcgcaagatg gtggttgaag atgagttgga caatggtatt cgtctttacc
     3961 tcaattttgg ccacactatt ggccatgcca tcgaagcgac tgccggttat ggcaaggtca
     4021 tgcatggaga ggctgttgcc atgggaatgg tacagatttc caagattgct gaggaaaaag
     4081 gcctcatgcc agctggcatt acccaatcta tcacagagat gtgtcagaaa ttcggcttgc
     4141 ctgttgacta tgaaaattgg gaagttgaca agctttatca ggctcttact catgacaaga
     4201 aagcgcgtgg caacaccttg aaattggtct tggtgccaga gcttggttca gcgaccattc
     4261 atccagtttc tctggaagag atgaaagact acttggtaaa ataaggagag tgtatgagat
     4321 atttaactgc aggagaatca cacggccccc gtctaacagc tattattgag ggaattccag
     4381 ctggacttcc attgacagct gaggatatca atgaggacct tagacgccgt cagggtggct
     4441 acggtcgtgg tggtcgtatg aagattgaga atgaccaggt tgtctttact tcgggcgttc
     4501 gccacgggaa gacgacaggg gcgcctatta ctatgtatgt catcaataag gaccaccaga
     4561 aatggctgga catcatgtct gcggaggaca ttgaagaccg ccttaaaagc aagcggaaaa
     4621 ttactcatcc tcgcccaggt catgccgatt tggttggggg gattaagtac cgttttgatg
     4681 atttgcgaaa ttctttggag cgttcatcag ctcgtgaaac caccatgcgg gtggcagttg
     4741 gtgcagtagc caaacgtctc ttggctgagc tggatatgga gattgccaac catgtcgtgg
     4801 tctttggtgg caaggaaatc gatgttcctg aaaatctgac agtcgctgaa attaagcaaa
     4861 gagctgccca gtctgaagtt tctattgtca accaagaacg agaacaggaa atcaaggact
     4921 atattgacca aatcaaacgt gatggtgata ccatcggtgg ggttgtggag acagtcgtcg
     4981 gaggcgttcc agttggtctt ggttcctatg tccaatggga tagaaaattg gatgcaagat
     5041 tggctcaagc tgttgtctct atcaatgcct ttaaaggggt ggaatttggt cttggctttg
     5101 aggctggtta tcgtaaaggc agccaagtta tggatgaaat tctctggtct aaagaagacg
     5161 gttatactcg ccgtaccaat aatctaggtg gttttgaagg tggtatgact aatgggcaac
     5221 ccatcgttgt tcgtggggtc atgaaaccca ttcctactct ttataaacct cttatgagtg
     5281 tggatatcga aacccacgaa ccttacaagg caaccgtgga gagaagtgat ccgactgctc
     5341 ttccagctgc aggaatggtc atggaagcag ttgtagcaac ggttctggcg caagaaatcc
     5401 tcgaaaaatt ctcatcagat aatcttgagg aactaaaaga agcggtagcc aaacaccgag
     5461 actatacaaa gaactattaa ggagttccta tggcaaaaac aatctatatc gcaggtcttg
     5521 ggttgattgg agcctctatg gcacttggta tcaaacgcga tcatccagat tatgaaattt
     5581 taggttataa tcgtagtcaa gcttcgagag atatcgcctt gaaagaaggc atgattgacc
     5641 gtgcaacgga tgattttgct agttttgctc ctttggcaga tgtcattatc ctcagcttgc
     5701 caatcaaaca aactattgct ttcattaagg agttggccaa tttggatttg cgagaaggcg
     5761 ttattatttc agatgctggt tcgaccaagt caaccattgt ggatgcggcg gagcagtatt
     5821 tggctggcaa gtctgttcgc tttgtcgggg cccatcccat ggctggtagt cacaagacag
     5881 gggctgcttc ggcagatgtc aatctttttg aaaatgccta ttatatcttt acaccttcaa
     5941 gcctgacaag tcaggacacg cttaaggaaa tgaaggatct gctttcaggt cttcatgctc
     6001 gttttatcga gattgatgcc aaggagcatg atcgtgtcac ttctcagatt agccattttc
     6061 ctcatatttt ggcttctagt ctcatggagc agactgcggt ctatgctcaa gagcatgaga
     6121 tggcaaggcg ctttgcggca ggtggttttc gagatatgac ccgaattgcg gaaagcgagc
     6181 caggaatgtg gacctccatt ctcttgtcca atagcgagac cattctggat agaattgagg
     6241 atttcaagga acgtttggaa gcgattggtc aggccattag taagggagat gaagagcaaa
     6301 tttggaactt ttttaaccaa gcgcgtgaac aacgccagac catggaaatc cataagcgtg
     6361 gtggtgtgga tagctcttac gacctctatg ttgacgttcc tgatgaagaa gatgtcatcc
     6421 tgcggatttt ggaactgcta cgtgggactt ccttggttaa catccacatc aacgaggaaa
     6481 atcgtgagga tattcacgga atcctacaaa tttcatttaa aaatgctcaa gacttggaaa
     6541 gagccgagca tctcataaca aaaaataccg actatacagt cgtcattaaa taaggagaag
     6601 aacatgtcaa atatttacga tagtgcaaac gacctcagtc gcggtctacg cggattacca
     6661 gaatacaagg ctgttaaagc agctaaagat gcgattgcag cagatgctga ggcaagcaaa
     6721 atctttacag aatatcttgc ctttcaagag gaaattcaaa aactagcaca gacaggtcaa
     6781 atgccagatg cgtccttcca agctaagatg gaaggctttg gtaaacagat tcaaggaaat
     6841 agcctcttgt cagaattctt taccaagcaa caacaattgg ccatttacct ttctgacatt
     6901 gaaaaaattg ttttcgaacc agtttcagaa ttgctgaaat aagaaaagaa ctatcctaaa
     6961 gtcaggaatt tttaaggaat ttctggcttt ttatgataaa ataggtaaaa gtattgcaag
     7021 tatgaggtcc agtatgaaac taaaaacaaa cattcgccat ttacatggta gtatccgcgt
     7081 cccaggtgac aagtctatca gccaccgttc cattatcttt ggaagtttgg ctgagggtga
     7141 gaccaaggtt tatgatattc tgcgaggtga agacgttctt tcgaccatgc aggtttttcg
     7201 tgaccttggt gttgaaattg aggataaaga tggggttatt accgttcaag gtgtaggcat
     7261 ggctggctta aaagcgccgc aaaatgccct taatatggga aattctggca cctcgattcg
     7321 cctgatttca ggtgtccttg ctggtgcaga tttcgaagta gagatgtttg gagatgatag
     7381 tctttccaaa cgtcctatgg accgtgtgac ccttccactg aaaaaaatgg gcgtcagcat
     7441 ctcagggcaa actgaacgag acttgcctcc ccttcgctta aaagggacga aaaacctaag
     7501 acctattcat tatgagttgc caattgcctc tgcccaagtc aagtcagcct tgatgtttgc
     7561 agccttacaa gctaaggggg agtcagttat tatcgaaaaa gagtacaccc gtaatcatac
     7621 tgaagatatg ttgcaacaat ttggtggtca tttaagtgtg gatggtaaga aaatcacagt
     7681 ccaagggcca caaaaattga caggacagaa ggtggtcgta ccaggagata tttccagtgc
     7741 agccttttgg ttagtcgcag gtttgattgc tccaaattct cgtctagtgc tgcagaatgt
     7801 ggggataaac gaaactcgca ccggtattat tgatgtcatt cgtgccatgg gtggaaaatt
     7861 ggaaataact gaaatcgatc cagtcgctaa atctgcaacc ttgattgttg agtcttctga
     7921 cttgaaagga acagagattt gtggcgcttt gattccacgt ttgattgatg aattgcctat
     7981 tattgcccta cttgcgaccc aagcccaagg tgtaacagtt atcaaggatg ctgaggagct
     8041 caaggtcaag gaaacagacc gtattcaggt tgtggcagac gccttaaata gtatgggagc
     8101 agatattact cctacggcag atgggatgat tatcaaagga aaatcagctc ttcacggtgc
     8161 tagagtcaat acgtttggtg accaccgtat cggcatgatg acagctatcg cagccctatt
     8221 ggttgcagat ggagaggtgg agcttgaccg tgcagaagcc atcaatacca gctatcctag
     8281 tttctttgat gatttggaga gcttgattca tggctaaggt gttattaggg tttatggggg
     8341 ctggaaaatc gactattgca agaggcttgg accctaatta ccttgatatg gatgctctga
     8401 ttgagaagcg cctaggtatg tccattgcga attttttcgc tgaaaaggga gaagcagcct
     8461 ttcgtcaggt agaatcagaa gtcctagctg atttattaca aagagaccaa gtcgtgtcaa
     8521 ctggaggagg agtggttatt tctcagagaa atcgtgactt actcaagact aatacagata
     8581 acatctacct gaaagcagat tttgaaaccc tctacctacg tatcgcagct gataaggaca
     8641 atcagcgacc gctttttcta aataatagca aggaagaact agtagctatt tttcaagaaa
     8701 gacaggcttg gtatgaggaa gtggctagtc gggttttgga tgtgaccaag ctaagcccag
     8761 aggaaattat agaggaacta agatgaaaat tgcttatcta ggtcccaaag gatcattttc
     8821 acaccacgtt gtgcagacag cttttcctca tgaggaattg caggcttttg ccaacattac
     8881 agatgtcatc aaggcttatg agcaaggatt agtggactat tctgtggtgc cagttgaaaa
     8941 ttctattgag ggtagtgttc atgaaacctt ggactatctt tttcatcagg ctcacatcca
     9001 agcagtagca gaaatcgttc agcctattca tcagcagttg atggtggttc caggccatac
     9061 taagattgaa aagatttttt cacatccaca ggccttggct caaggaaaga aattcatcga
     9121 tgaacaatat ccagaggctc aaatcgaggt aacagctagt acagcttatg cggcccgttt
     9181 tatttccgaa catccagatc agccctttgc agcaattgca cctagaagtt ctgctgaaga
     9241 atatggattg gaactgattg ccgaggatat tcaggaaatg gaagccaatt tcacacgttt
     9301 ctggcttcta ggagctgaaa agcctagtat tcccttgcaa gcacaaactg aaaagatgag
     9361 tttggccttg acattacctg acaaccttcc aggtgcactt tataaggccc tgtcgacctt
     9421 tgcttggcga ggaattgact tgacaaaaat tgaaagtcgt ccactcaaga cagcactggg
     9481 tgaatacttt ttcattatcg atgtggatta taccgataag gacttggtcc actttgccca
     9541 aaaagaatta gaagcgattg gaatccagta taaaattctg ggtgcctatc ctatttatcc
     9601 aatatcagac catggaaagg agagaagatg agtaaagaaa atcccttaag tcatcatgag
     9661 cagttgcgtt atgattattt gctaaaaaat attcactatc tcaatgagag agaaaaaaat
     9721 gagtttgtct atttgcaaga aaagctaact cttgctaggg gaaatagtag ctctagcttg
     9781 gaacaagaaa gagaagagca ggttgactta ccaagctatg cgaaccggag tcgctcacaa
     9841 tccaaatcac aagcactctc tttccctcca aaaaagaaaa gacggaagct ccgtcttaaa
     9901 cgaattttta tggtgatttt ttcacttttg gtctgtgtgg ctttggccat ggtattcatg
     9961 tttttgcgtg gttaccaaga tgctagcgca aagaaaactg ctgatgcccg ggcagctcaa
    10021 gtagaagtct ttaatggtca ggacactaga gatggagtta atattttaat catgggtact
    10081 gatggtcgaa tcggccagaa cagtgttgag acacgaactg actctattat ggtattaaat
    10141 gtcgggggct cagataagaa aatgaagcta gtcagtttca tgcgtgataa tttggtctat
    10201 atagatggtt atagtcaagt gattaacggt agaaaacaga cagataacaa gttaaacgta
    10261 gcctacgagt taggagaaca agaggggcaa aaaggggcag aaatggttcg ccaagtcttg
    10321 aaagataatt ttgacttgga cattaagtac tacgccttgg ttgatttcca ggcctttgcc
    10381 acagcgattg acacgctttt ccctgatggg gtgacgattg atgctcaatt ttcaacattg
    10441 aatgggcgtc ccctaacaga agctacagtc ggagatgatt tatacgctac cgagactgag
    10501 tctccaaccc aaaccattaa agtcggaaaa cagcagatga atggctcgac cctgctcaat
    10561 tatgctcgtt tccgtgatga tgatgaggcg gattacggcc gtacaaaaag acagcaacaa
    10621 gttttaacag caattttaga gcaaattaaa gatcccacta aacttttcac tggttctgaa
    10681 gctcttggaa aggtttttgc tatgacctca accaacgtac cctatacttt cctcctaaca
    10741 aacggtttat ctgttttgga tggagcaaaa aatggtattg aaaaattgac gattccagaa
    10801 ctgggtgact gggtagatgc ctatgatgtt tatggaggct tgggcttgct ggttgatcaa
    10861 aacaaatatc aaaccaagct cgctcaaatg ggcttgagat aagataatac tcaatgaaaa
    10921 tcaaagtgca aattaggaag ctagccgcag gctgctaaaa acacagtttt gaggttgtag
    10981 ataagactga cgaagtcagt tacctatacc tacggcaagg tgaagctgac gttgtttgaa
    11041 gagattttcg aagagtataa gacagaaaaa tcaaagtttg atagctattt ggatagcagt
    11101 caggctttga ttttttacag tctgcaatag attttcaccc cttgtttgtg gtataatgaa
    11161 acgatacgat agaaagaata atgaataata tgactgattt aaaagcaatt caggctcgta
    11221 gtctggagat ggctgaatat tttgtggcct tttgtaaaga acatgatttg ctctgttatc
    11281 tctgtggcgg aggcgctatt ggtgcccttc gaaacaaggg atttattcct tgggacgacg
    11341 acctagactt ttttatgcct cgtaaagatt atgagaaatt agcagaatta tggcctcgtt
    11401 atgcagatga acgttatttc ttgtcaaaga gtcacaagaa ttttgttgat cgtaatcttt
    11461 ttattaccat tcgtgacaag gaaaccacct gtatcaagcc ttatcagcag gatttggatt
    11521 tgccacatgg tctggccttg gatgttttgc ctttggatta ttatccgaaa aatccagctg
    11581 agcggaaaaa acaggttcgt tgggccttga tttattcact cttttgtgcg caaactattc
    11641 cagaaaagca tggtgctctc atgaaatggg gaagtcgcat tttactgggt ttgactccaa
    11701 aatctctccg ttatcgcatc tggaaaaaag ctgagaaaga aatgactaag tatgatttgg
    11761 ctgattgtga tggcattaca gaattatgct caggtcctgg ctacatgaga aacaagtacc
    11821 caatcacatc ttttgaagac aatcttttct tgccatttga aggaacagag atgcctattc
    11881 caatcggcta tgatgtctat ctcagaactg cttttgggga ttatatgacg cctccaccag
    11941 cagacaagca ggtaccgcat catgatgctg tcatcgctga tatggataag tcttatacag
    12001 aatacaaggg agaatatggt ggctaagaaa aaaatcttat tttttatgtg gtctttttct
    12061 cttggaggtg gtgcagagaa gattctatca accattgttt caaatctgga tccagaaaag
    12121 tatgatattg atattcttga aatggagcac tttgacaagg gatatgaatc tgttccaaag
    12181 catgtacgca ttttaaaatc ccttcaagat tatcgccaaa ccagatggtt acgagctttt
    12241 ttgtggagaa tgagaattta ttttccaaga ctgactcgtc gtttgcttgt aaaagatgat
    12301 tatgatgttg aagtttcttt taccattatg aatccaccac tgttgttctc taaaagaaga
    12361 gaagtcaaga agatatcttg gattcatgga agtattgaag aacttcttaa ggatagctct
    12421 aaaagagaat cacatagaag ccagttggat gctgcgaata caattgtagg gatttcaaaa
    12481 aagaccagca attctatcaa ggaagtttat ccagattatg cttctaaatt acagacaatc
    12541 tacaatggat atgattttca gactattcta gaaaaatctc aagagaagat cgatatcgag
    12601 attgctcctc aaagtatctg tactatcgga cggattgagg aaaataaggg ttctgaccgt
    12661 gtagtggaag tgatacgatt attacaccaa gagggaaaaa actatcatct ctattttatc
    12721 ggggctggtg atatggaaga ggaactgaaa aaacgagtca aagagtatga gattgaggac
    12781 tatgtacatt tccttggtta tcaaaaaaat ccttatcagt atttatctca gacgaaagtt
    12841 ctcttgtcta tgtctaaaca agaaggcttt cctggagtgt atgtggaggc cttgagtctg
    12901 ggactccctt ttatctctac ggacgttgga ggggctgagg aattatccca agaaggacga
    12961 tttggacaaa tcattgagag caatcaagag gcagctcagg cgattactaa ttacatgact
    13021 tctgcctcaa actttaatgt cgatgaggct agccaattca ttcaacaatt tacaattaca
    13081 aaacaaatcg aacaagtaga aaaactatta gaggagtagc atggaaactg cattaattag
    13141 tgtgattgtg ccagtctata atgtggcgca gtacctagaa aaatcgatag cttccattca
    13201 gaagcagacc tatcaaaatc tggaaattat tcttgttgat gatggtgcaa cagatgaaag
    13261 tggtcgcttg tgtgattcaa tcgctgaaca agatgacagg gtgtcagtgc ttcataaaaa
    13321 gaacgaagga ttgtcgcaag cacgaaatga tgggatgaag caggctcacg gggattatct
    13381 gatttttatt gactcagatg attatatcca tccagaaatg attcagagct tatatgagca
    13441 attagttcaa gaagatgcgg atgtttcaag ctgtggtgtc atgaatgtct atgctaatga
    13501 tgaaagccca cagtcagcca atcaggatga ctattttgtc tgtgattctc aaacatttct
    13561 aaaggaatac ctcataggtg aaaaaatacc tgggacgatt tgcaataagc taatcaagag
    13621 acaaattgca actgccctat cctttcctaa ggggttgatt tacgaagatg cctattacca
    13681 ttttgattta atcaagttgg ccaagaagta tgtggttaat actaaaccct attattacta
    13741 tttccataga ggggatagta ttacgaccaa accctatgca aagaaggatt tagcctatat
    13801 tgatatctac caaaagtttt ataatgaagt tgtgaaaaac tatcctgact tgaaagaggt
    13861 cgcttttttc agattggcct atgctcactt ctttattctg gataagatgt tgctagatga
    13921 tcagtataaa cagtttgaag cctattctca gattcatcgt tttttaaaag gctatgcttt
    13981 tgctatttct aggaatccaa ttttccgtaa ggggagaaga attagtgctt tggccctatt
    14041 cataaatatt tccttatacc gattcttatt actgaaaaat attgaaaaat ctaaaaaatt
    14101 acattagaac gggggtgacc aagtgattga tgggaaacga ttattattta gtttgaccat
    14161 agtcagttat accttgacgc tagtaagtgg aattgtgtat ctgtttaata ataataatgt
    14221 tagcttactt tctactttat tgttcttgtt ggttagtagc ttaattgctt gttggaatga
    14281 tatcaagtat tacttaatcc attttatttt ctatttaacc atttttgtat ttctggtatc
    14341 aagaccgacc attgattatt ttagggatgg tgctttggat acctatcatc caatagccta
    14401 tcgttttgcc tttatagttg tcatgatttc gattctgggc ttgaccacag gaggcgtcct
    14461 ggctcgttac ttcatagcta ggaagaaaat aaaagtagca aatataggaa attctctaaa
    14521 agaggtttat atcaagcggt tacgctttgt atcactagga gtttttcttc taacctatcc
    14581 tttctatttc attcggttat ttgaacggct cttgtatcgt ttgcagactt cctactatgc
    14641 ctactatgca aattttgaaa gtaaactgcc ttattttacc tacattttgt ctacctttac
    14701 ggtctatgca atgtgtatgt atctggcaac caagccaaag aaattgcagg ccacagcagt
    14761 gcttgtctcc tttattgcag ctaatactat tcatttggca attgggacac gaaatccctt
    14821 tattttaagt attttatttg cttttgttta ttactttatg cgggagcaaa ctgaaaaagg
    14881 aaaatggatt gggtttaaag aaaagttagc gatttttgta ggttctccta ttctcatgtt
    14941 agcgatggga gtacttaatt atgtacggga taatgtccaa gtttcccata caggtttctg
    15001 ggatatctta cttgacttta tctataaaca aggaactagt tttggtgttc tggctcgagg
    15061 ttttctattt aacagtagcc tcccttaccg agatttccgt aattttactt ttggtcctgt
    15121 tcttgattat tttgcaaggg ggagtttggg agccattttc ggaggaaaag cctttgaaca
    15181 tacaaccaat agtgtggaac tagctattga tagtaatagt tatgcccaca atctatccta
    15241 tcttgtcttg aacaaggaat acttgaaagg gcatggtatc ggaagtagtt atatcatgga
    15301 gttgtatacc gactatggta tgattggagt ctttctgctt agtttcttac tcggcgtatt
    15361 atttatagcc atgctgcaag tagcctatcg ctcaaggaca atcctatttg ctttatccct
    15421 actcatcttg aataatctat tctttatgcc aagaagcagc ttttcagaaa gtttcttcaa
    15481 tttatttaca atgcaattct ggggaattgt tcttgtgatt atatttgtag caaaaatgct
    15541 tacaaaggaa aactagtatc tactaaacaa aggagaaaaa aatcatgttt gaacattatt
    15601 cagtagctga tttgtttgca aatctttata aaaaacgaaa agcaaatatt ttagctctca
    15661 tcgctttatt tgctctcatt gctgtaccat ttacaattaa agcagttagg aataaaaaca
    15721 ctgtcaaaga tacaacaagt tattcaactt atcttatcta taaaatcact cctccagaag
    15781 attcggccaa aacgattttg aatcatcaaa ttggtggtta tagtgatttt tatgggaaat
    15841 tgattgatgg taatttgaat ggagcttatc ttttcaatga tgtagaaccc agtgagttga
    15901 aaaaaattgc cagtgaatta gacacgacgg aaacaacctt gaaaaattca acgaatgact
    15961 attggtggaa aaaattgacc gtctactata tgattgacga tgcaggggtt ggtgtgaaaa
    16021 ttttgacatc aagtaaagat gccaatgact tgttagagaa aaaaattgat gggttgattg
    16081 agaaatttaa acatgcttat gcaaatgtga aaattgaaaa actggaaacc atcaactcta
    16141 aagaattgaa cgcaaatggt gaaacagcgc ttggcttaaa tgtgaaaaat ctgattcttc
    16201 gtttagttgt tattggagtg gtttgtgtga ttttggttgt gatgggaaat gtgttagttt
    16261 atctctttaa tccaacaatc aatagagtag gtgatttttc tcagtatcaa attgattttg
    16321 taacagagat tacaacaatt gctaacctag cagatgtttt gtcatacaaa aatactggac
    16381 aggaattgac catcgttagc tcaaataaag ctatcctaga taaattgaaa cagagtcaag
    16441 aagctttaaa aggaatgcat tttgtagatt tgcaggatgt atcatctctt ttggaaagag
    16501 atacagtcct tcttgttgaa gagtacggag tgactcgtta taagaaattt gagcaaagtc
    16561 ttcaaattct cagaaactta aatcgttcta tcctcggtgt agcaaccttt aaattataag
    16621 tattctgatg tataaggtct tcaaaatcgg ctaagagccg attttgaagg ctttttctat
    16681 ctgtctgcag aaattttctc ttggagtctc ctatagaaag accctaggga aaatctatcc
    16741 gtatagagga gccttctttt gataaaatcg taaaaatcta gtataataga tagaactgaa
    16801 agtatgaggt tactagcaat gaaaatgaaa caaattagtg atacaacttt aaaaatcacg
    16861 atgtctttag aggatttgat ggatcgtgga atggagattg ctgactttct cgttcctcaa
    16921 gaaaaaacag aagagttctt ttatgctatc ttggatgagc tagagatgcc tgatagcttt
    16981 ctggatacag gcatgttgag cttccgtgtg actccaaaac ctgataaggt agatgtcttt
    17041 gtgaccaagt caaagattga ccaaaatcta gattttgaag acttatcgga tttgccagat
    17101 atggaagaat tggctcaaat gtctccagat gaatttatca aaaccctgga aaaaagcatc
    17161 gcagacaaaa ccaaggatga tatcgaagcc attcaatctc ttgagcaagt tgaagccaag
    17221 gaagaagagc aagagcaggc tgaacaagaa gctgagagta agaaagaacc ttacatctac
    17281 tacatccttt cttttgctaa gttggctgac ttggtagctt ttgccaagac agtgactttt
    17341 gaaatggaaa cttctgaact ctacaaaatg aacgagcgct attatttgac cattttagtg
    17401 gatattgaaa atcatccaag cccatatcca gcttggctgt tggcccgtat gcgcgagttt
    17461 gcagacgata gtgatatcag tcgctcagtc ttacaagagt atggtcaagt cttgatgagt
    17521 cacgatgcag tgctcaatct gcaaaaaatc ggctaatcct ttctggaaag ctattttcag
    17581 attttaagaa gagcgaatcg tctgattcgt tttttctttt tatactgaaa tagtgattta
    17641 ctataatagg aattttcaca aaattctgtt ataatggcta tattagaaaa tttcgaggag
    17701 ataaagatga cagttaaaat tgctttacta ggatttggta ccgttgcaag tggtgtgcct
    17761 ttcctcctaa aggaaaatgg aggaaaaatc aatcaatcag cacattcaga tatcaaagtt
    17821 gctaaggtat tggtcaagga tgaagatgaa aaaaatcgct tgcttgcagc agggaatgac
    17881 tttaactttg taaccaatgt ggatgatatt ttatcagacc aggatattac tatcgtagtg
    17941 gaattgatgg ggcgtattga gcctgctaaa acctttatca ctcgtgcctt ggaagctgga
    18001 aaacacgttg ttactgctaa caaggacctt ttagctgtcc atggcgcaga attgctagaa
    18061 atcgctcaag ctaacaaggt agcattttac tacgaagcag cagttgctgg tgggattcca
    18121 attcttcgta ctttagcaaa ttccttggct tctgataaaa ttacgcgcgt gcttggagta
    18181 gtcaacggaa cttccaactt catggtgacc aagatggtgg aagaaggctg gtcttacgat
    18241 gatgctcttg cggaagcaca acgtctagga tttgcagaaa gcgatccgac gaatgacgta
    18301 gatgggattg atgcagccta caagatggtt attttgagcc aatttgcctt tggcatgaag
    18361 attgcctttg atgatgtagc ccacaaggga atacgcaata tcacaccaga agacgtagct
    18421 gtagctcaag agcttggtta cgtagtgaaa ttggttggtt ctattgagga aacttcttca
    18481 ggtattgctg cagaagtgac tccaaccttc ctacctaaag cgcacccact tgctagtgtg
    18541 aatggcgtaa tgaacgctgt ctttgtagaa tctatcggta ttggtgagtc tatgtactac
    18601 ggaccaggtg cgggtcaaaa accaactgca acaagtgttg tagctgatat tgtccgtatc
    18661 gttcgtcgtt tgaatgatgg taccattggc aaagacttca acgaatatag ccgtgacttg
    18721 gtcttggcaa atcctgaaga tgtcaaagca aactactatt tctcaatctt ggctccagac
    18781 tcaaaaggtc aggtcttgaa gttggctgaa atcttcaatg ctcaagatat ttcctttaag
    18841 caaatccttc aagatggcaa agagggtgac aaggcgcgtg tcgttatcat cacacacaag
    18901 attaataaag cccagcttga aaatgtctca gctgaattga agaaggtttc agaattcgac
    18961 ctcttgaata ccttcaaggt gctaggagaa taagatgaag attattgtac ctgcaaccag
    19021 tgccaatatc gggccaggtt ttgactcggt cggtgtagct gtaaccaagt atcttcaaat
    19081 tgaggtctgc gaagaacgag atgagtggct gattgaacac cagattggca aatggattcc
    19141 acatgatgag cgtaatctct tgctcaaaat cgctttgcaa attgtaccag acttgcaacc
    19201 aagacgcttg aaaatgacca gtgatgtccc tttggcgcgc ggtttgggtt cttccagctc
    19261 ggttatcgtt gctgggattg aactagccaa ccaactgggt caactcaact tatcagacca
    19321 tgaaaaattg cagttagcga ccaagattga agggcatcct gacaatgtgg ctccagccat
    19381 ttatggtaat ctcgttattg caagttctgt tgaagggcaa gtctctgcta tcgtagcaga
    19441 ctttccagag tgtgattttc tagcttacat tccaaactat gaattacgta ctcgcgacag
    19501 ccgtagtgtc ttgcctaaaa aattgtctta taaggaagct gttgctgcaa gttctatcgc
    19561 caatgtagcg gttgctgcct tgttggcagg agacatggtg accgctgggc aagcaatcga
    19621 gggagatctc ttccatgagc gctatcgtca ggacttggta agagaatttg cgatgattaa
    19681 gcaagtgacc aaagaaaatg gggcctatgc aacctacctt tctggtgctg ggccgacagt
    19741 tatggttctg gcttctcatg acaagatgcc aacaattaag gcagaattgg aaaagcaacc
    19801 tttcaaagga aaactgcatg acttgagagt tgatacccaa ggtgtccgtg tagaagcaaa
    19861 ataaagaata gaagatagga tggggaaact cttgaccaga gggtttcata tcctttttgt
    19921 gaaaagaagt ttatactcaa tgaaaatcaa agagcaaact aggaagctag ccgcaggctg
    19981 ctcaaaacag tgttttgagg ttgtggatag aactgacgaa gtcagtaaca tatatacggt
    20041 aaggtgacgc tgacgtggtt tgaagagatt ttcgaagagt attagttaaa aacgtgataa
    20101 aggagaaata aagatggcag aaatttatct agcaggtggt tgtttttggg gcctagagga
    20161 atatttttca cgcatttctg gagtgctaga aaccagtgtt ggctacgcta atggtcaagt
    20221 cgaaacgacc aattaccagt tgatcaagga aacagaccat gcagaaacgg tccaagtgat
    20281 ttacgatgag aaggaagtgt cactcagaga gattttactt tattatttcc gagttatcga
    20341 tcctctatct atcaatcaac aagggaatga ccgtggtcgc caatatcgaa ctgggattta
    20401 ttatcaggat gaagcagatt tgccagctat ctacacagtg gtacaggagc aggaacgcat
    20461 gctgggtcga aagattgcag tagaagtgga gcaattacgc cactacattc tggctgaaga
    20521 ctaccaccaa gattatctca ggaagaatcc ttcaggttac tgtcatatcg atgtgaccga
    20581 tgctgataag ccattgattg atgcagcaaa ctatgaaaag cctagtcaag aggtgttgaa
    20641 ggccagtcta tctgaagagt cttatcgtgt cacacaagaa gctgctacag aggctccatt
    20701 taccaatgcc tatgaccaaa cctttgaaga ggggatttat gtagatatta cgacaggtga
    20761 gccactcttt tttgccaagg ataagtttgc ttcaggttgt ggttggccaa gttttagccg
    20821 tccgatttcc aaagagttga ttcattatta caaggatctg agccatggaa tggagcgaat
    20881 tgaagttcgt tctcgttcag gcagtgctca cttgggtcat gttttcacag atggaccgcg
    20941 ggagttaggc ggcctccgtt actgtatcaa ttctgcttct ttacgctttg tggccaagga
    21001 tgagatggaa aaagcaggat atggctatct attgccttac ttaaacaaat aaaacagaga
    21061 gtggggcttc ccactttctt catttctaga atatgaatag aagggattta tgaaacacct
    21121 attatcttac ttcaaaccct acatcaagga atcaatttta gcccccttgt tcaagctgtt
    21181 agaagctgtt tttgagctct tggttcccat ggtgattgct gggattgttg accaatcttt
    21241 acctcaggga gatcaaggtc atctctggat gcagattggc ctgctcctta tctttgcagt
    21301 aattggcgtt ttagtggcct tgatagctca attttactca gcaaaggcag cagtaggttt
    21361 tgctaaggaa ttgacaaacg atctttatcg tcatattctt tccttgccca aggacagcag
    21421 agaccgtctg acaacttcta gtttggttac tcgcttgact tcggatacct accagattca
    21481 gactggtatc aatcaattcc tgcgtctctt tttacgagcg cccattatcg tttttggtgc
    21541 catttttatg gcttatcgaa tctcagctga gttgactttc tggttcttag tcatggttgc
    21601 cattttgacc attgtcattg tagggttatc tcgattggtc aatcctctct acagtagtct
    21661 cagaaagaaa acggaccaac tggttcagga aacgcgccag caattgcaag ggatgcgggt
    21721 tattcgtgct tttggtcaag aaaaacgaga gttacagatt tttcaaaccc ttaaccaagt
    21781 ttatgctaga ttacaagaaa agacaggttt cttgtctagt ttattaatac ctctgaccta
    21841 tctgattgtc aatggaactc ttctcgttat tatctggcaa ggctatattt caattcaagg
    21901 aggagtactc agtcaaggtg ctctcattgc tcttatcaat tacctcttac agattttggt
    21961 ggaattggtc aagctagcca tgctgatcaa ttccctcaac cagtcctata tctcagccaa
    22021 gagaatcgag gaggtctttg cggaatctcc cgaaaacatc cattcagaat tagaacaaaa
    22081 gcaagttacc agtggtcggg ttttacaagt ccaagaattg acttttacct atcctgatgc
    22141 ggcccagcct tctctgagag acatttcctt tgatatgact caaggacaaa tccttggtat
    22201 cattgggggg actggttctg gtaaatcaag cttggtgcaa ctcttacttg gactttatcc
    22261 agtagacaag gggaacattg acctttatca aaatggacgt agtcctctta atttggagca
    22321 gtggcggtct tggattgcct atgtacctca aaaggtcaaa ctctttaagg gaactattcg
    22381 ttccaacttg actttaggtt taaatcaaga agtatctgac cagaaactct ggcaggcctt
    22441 ggagattgcg caagctaagg attttgtcag tgaaaaggaa ggacttttgg atgccctagt
    22501 tgaggcaggg gggcgaaatt tctcaggtgg acaaaaacaa aggttgtcta tcgcccgagc
    22561 agtcttgcgc caagctccgt ttatcatcct agatgatgca acctcggcac tggataccat
    22621 tacagagtcc aagctcttga aagctattag agaaaatttt ccaaacacga gcttaatttt
    22681 gatctctcaa cgaacctcaa ctttacagat ggcggaccag attctcctct tggaaaaagg
    22741 tgagttgcta gctgttggca agcacgatga cttgatgaaa tccagccaag tctatcgtga
    22801 aatcaatgca tcccaacatg gaaaggagga ctagaatgaa acgacaaact gtaaaccaga
    22861 cgctcaaacg tttagccgta gatttagcaa accatccctt cctccttttc ctagcctttc
    22921 taggaactat tgcccaagtt ggcttatcaa tttacctacc tattctgatt gggcaggtca
    22981 ttgaccaagt cctagtggct ggttcatcac cagttttttg gcagattttt ctccagatgc
    23041 tcttggtggt aataggaaat actctggtac aatgggccaa tcctctcctc tataatcgtc
    23101 taatcttctc ttataccaga gatttgcgag agcgaatcat ccataagctc catcgtttac
    23161 cgattgcttt tgtagatagg caaggtagtg gagagatggt tagtcgtgta accacggaca
    23221 tcgaacagtt ggcagctggc ttgaccatga tttttaacca atttttcatt ggtgttttga
    23281 tgattctggt tagtattcta gccatgctcc aaattcatct cctcatgact ctcttagtct
    23341 tgctgttgac gccactgtcc atggtgattt cacgctttat tgccaagaga tcctatcatc
    23401 tcttccagaa gcaaacagag acgaggggaa ttcagactca gttgattgaa gaatcgctta
    23461 gccagcagac tataatccag tccttcaatg ctcaaacaga atttatccaa agattgcgtg
    23521 aggctcatga caactactca ggctattctc agtcagccat cttttattct tcaacggtca
    23581 atccttcgac tcgctttgta aatgcactca tttatgccct tttagctgga gtaggagctt
    23641 atcgtatcat gatgggttca accttgaccg tcggtcgttt agtgactttt ttgaactatg
    23701 ttcagcaata caccaagccc tttaatgata tttcttcagt gctagctgag ttgcaaagtg
    23761 ctctggcttg cgtagagcgt atctatggag tcttagatag ccctgaagtg gctgaaacag
    23821 gtaaggaagt cttgaccagt gaccaagtta agggagctat ttcctttaaa catgtctctt
    23881 ttggctacca tcctgaaaaa attttgatta aggacttgtc tatcgatatt ccagctggta
    23941 gtaagatagc catcgttggt ccgacaggtg ctggaaaatc aactcttatc aatctcctta
    24001 tgcgttttta tcccattagc tcgggagata tcttgctgga tgggcaatcc atttatgatt
    24061 atacacgagc atcattgaga cagcagtttg gtatggtgct tcaagaaacc tggctcacac
    24121 aagggaccat tcatgataat attgcctttg gcaatcctga agccagtcga gagcaagtaa
    24181 ttgctgctgc caaagcagct aatgcagact ttttcatcca acagtttcca cagggatacg
    24241 ataccaagtt ggaaaatgct ggagaatctc tctctgtcgg ccaagctcag ctcttgacca
    24301 tagcccgagt ctttctggct attccaaaga ttcttatctt agacgaggca acttcttcca
    24361 ttgatacacg gacagaagtg ctggtacagg atgcctttgc aaaactcatg aagggccgca
    24421 caagcttcat cattgctcac cgtttgtcaa ccattcagga tgcggattta attcttgtct
    24481 tagtagatgg tgatattgtt gaatatggta accatcaaga actcatggat agaaagggta
    24541 agtattacca aatgcaaaaa gctgcggctt ttagttctga ataagccatt ctcttttgaa
    24601 agtttatgga cgaaaaaagt tgccttcgag tgactttttt gttacaatag ctagaaaaat
    24661 tgttcactgt aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgtaggttgc
    24721 tcaaaacagt gttttgaggt tgcagataga actgacgaag tcagtaacca cacctacggc
    24781 aaagtgaatt tgaagtggtt tgaagagagt acaacttgtc ttttagaaaa ggagcctata
    24841 atgaaagtct ttcagcatgt aaatatcgtg acttgtgatc aagatttcca tgtttatctt
    24901 gatggaatct tagcagtcaa ggattctcaa atcgtctatg tcggtcaaga taagccagcg
    24961 tttttagaac aagctgagca gattatagac tatcagggag cttggattat gcctggtttg
    25021 gtcaattgtc acacccattc tgcaatgaca ggtctgagag ggatccgaga tgacagcaat
    25081 ctccatgaat ggctcaatga ctatatctgg ccagcagaat ctgagtttac tcccgacatg
    25141 actaccaatg cggtcaaaga agccctaaca gagatgctcc agtcaggaac aacaaccttt
    25201 aacgatatgt ataatcccaa tggtgtggat atccagcaaa tttatcaggt ggtgaaaact
    25261 tccaagatgc gttgttattt ttctccgact ctcttttctt cagagacaga aacaactgct
    25321 gagactataa gcagaactcg atccatcata gacgaaatct taaaatataa aaatccaaat
    25381 ttcaaggtta tggtagcacc tcattctccg tatagctgca gtagagactt gctggaagcg
    25441 agtttggaaa tggcaaaaga gctaaatatt ccgctccatg tccatgtggc ggagaccaag
    25501 gaggagtcag gaattatcct caaacggtac ggcaaacgcc cccttgcttt tcttgaagaa
    25561 ctgggttatt tagatcatcc gtccgtattt gctcacgggg tcgaattaaa cgagagagaa
    25621 attgaactct tggcatcttc tcaagtggct atcgcccaca atcctatcag taacctcaaa
    25681 ctggcatcag gaattgctcc aattatccag ctccaaaaag cgggagtagt agtcggaatt
    25741 gcgactgact cggttgcttc caataacaat ctagatatgt ttgaggaagg aaggactgca
    25801 gctcttcttc agaagatgaa aagtggggat gccagccagt ttccaatcga aacagctctc
    25861 aaggtactga caatcgaagg ggctaaggtc cttggaatgg aaaatcagat aggaagtctg
    25921 gaagtcggca agcaagcaga ttttctggtc attcaaccac aagggaaaat tcatctccaa
    25981 cctcaggaaa atatgctgtc tcacctggtt tatgcagtta aatctagtga tgtagatgat
    26041 gtttatatcg ccggagaaca ggttgttaag caaggtcaag tcctgatagt agaactttaa
    26101 aagaaaaat
//
LOCUS       DAVKAU010000024        22445 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVKAU010000024 DAVKAU010000000
VERSION     DAVKAU010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.024"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(1..523)
                     /locus_tag="VWX48_001189"
                     /pseudo
     CDS             complement(1..523)
                     /locus_tag="VWX48_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            complement(907..2103)
                     /gene="tuf"
                     /locus_tag="VWX48_001190"
     CDS             complement(907..2103)
                     /gene="tuf"
                     /locus_tag="VWX48_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9171819.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(3014..3883)
                     /locus_tag="VWX48_001191"
     CDS             complement(3014..3883)
                     /locus_tag="VWX48_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9171820.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYTATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(4106..4627)
                     /locus_tag="VWX48_001192"
     CDS             complement(4106..4627)
                     /locus_tag="VWX48_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9171821.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(4585..5691)
                     /locus_tag="VWX48_001193"
     CDS             complement(4585..5691)
                     /locus_tag="VWX48_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU9171822.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVRVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5802..6056)
                     /locus_tag="VWX48_001194"
     CDS             complement(5802..6056)
                     /locus_tag="VWX48_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171823.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(6396..6929)
                     /locus_tag="VWX48_001195"
     CDS             complement(6396..6929)
                     /locus_tag="VWX48_001195"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9171824.1"
                     /translation="MTSFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVGGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLERFFKTR"
     gene            complement(6916..7131)
                     /locus_tag="VWX48_001196"
     CDS             complement(6916..7131)
                     /locus_tag="VWX48_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9171825.1"
                     /translation="MGKERREQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(7098..7241)
                     /locus_tag="VWX48_001197"
     CDS             complement(7098..7241)
                     /locus_tag="VWX48_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEU9171826.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7475..9193
                     /locus_tag="VWX48_001198"
     CDS             7475..9193
                     /locus_tag="VWX48_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU9171827.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIETPFAVEVADVETEKASGLIEVIGEVVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9304..9651
                     /locus_tag="VWX48_001199"
     CDS             9304..9651
                     /locus_tag="VWX48_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9171828.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGALSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9929..10765)
                     /locus_tag="VWX48_001200"
     CDS             complement(9929..10765)
                     /locus_tag="VWX48_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9171829.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10778..11407)
                     /locus_tag="VWX48_001201"
     CDS             complement(10778..11407)
                     /locus_tag="VWX48_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9171830.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAESYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11417..12058)
                     /locus_tag="VWX48_001202"
     CDS             complement(11417..12058)
                     /locus_tag="VWX48_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9171831.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12204..13433)
                     /locus_tag="VWX48_001203"
     CDS             complement(12204..13433)
                     /locus_tag="VWX48_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU9171832.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLNTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13423..14589)
                     /locus_tag="VWX48_001204"
     CDS             complement(13423..14589)
                     /locus_tag="VWX48_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9171833.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14733..15746
                     /locus_tag="VWX48_001205"
     CDS             14733..15746
                     /locus_tag="VWX48_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU9171834.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15791..16210)
                     /locus_tag="VWX48_001206"
     CDS             complement(15791..16210)
                     /locus_tag="VWX48_001206"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU9171835.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16221..17627)
                     /gene="atpD"
                     /locus_tag="VWX48_001207"
     CDS             complement(16221..17627)
                     /gene="atpD"
                     /locus_tag="VWX48_001207"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU9171836.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17713..18591)
                     /locus_tag="VWX48_001208"
     CDS             complement(17713..18591)
                     /locus_tag="VWX48_001208"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU9171837.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18607..20112)
                     /locus_tag="VWX48_001209"
     CDS             complement(18607..20112)
                     /locus_tag="VWX48_001209"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU9171838.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(20127..20663)
                     /locus_tag="VWX48_001210"
     CDS             complement(20127..20663)
                     /locus_tag="VWX48_001210"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU9171839.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20663..21157)
                     /gene="atpF"
                     /locus_tag="VWX48_001211"
     CDS             complement(20663..21157)
                     /gene="atpF"
                     /locus_tag="VWX48_001211"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU9171840.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(21171..21887)
                     /gene="atpB"
                     /locus_tag="VWX48_001212"
     CDS             complement(21171..21887)
                     /gene="atpB"
                     /locus_tag="VWX48_001212"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU9171841.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21922..22122)
                     /locus_tag="VWX48_001213"
     CDS             complement(21922..22122)
                     /locus_tag="VWX48_001213"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU9171842.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(22197..>22445)
                     /locus_tag="VWX48_001214"
     CDS             complement(22197..>22445)
                     /locus_tag="VWX48_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9171843.1"
                     /translation="YYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWI
                     NNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT         6670 a         4829 c         4092 g         6854 t
ORIGIN      
        1 aacgtctact ggttttaaag cgctttcttg tcttcttgaa ttgagatttt atttttagac
       61 gcgacaatgg tttgagcgtc tgctttctta ggatgttctg gacgtggcat aatatttcgc
      121 caaccatggc gcttcaacag ttgatagaag gcatcacgtg tgtaggaacg acctaactcc
      181 tttttataag cctgaaataa ggcatcaatt gtaacaaatt ctcctgcctc tgcagccttc
      241 aaatggcggg caagaaagac tttctcttcc tcaactgtca tatatgcatg gttacgacca
      301 ccacgtgttt cttgaaggag agagtcgagt ccgaactcct catatttttt tacatttcgc
      361 caaatcattg tttgattaca gtctaaaagt tctataatct ctttataaga tttgcccata
      421 tcagacgaaa tagaacgatt tgaagacgtt tatgatattt agctgtacga gagtctttta
      481 aaagtgtttt gatggtttgg atttcttctt taattgattt catattacta ttgtataatg
      541 ctttttgatt ttagtctagt attatactct tcgaaaatct cttcaaaccg cgtcagcttc
      601 gccttgtcgt atagatgtta ctgacttcgt cagttctatc tacaacctaa aaacagtgtt
      661 ttgagcagtc tgtagctaac tttctatagt aaaatgaaat aagaacaaga caaatcgatc
      721 aggacagtca aatcgatttc taacaatgtt ttagaagtaa atgtgtacta ttctagtttc
      781 aatatattat agtttgctct ttgattttca ttgagtatta gttcaatatc taaaaaaaga
      841 accttgccaa gcaagattct tttagtgtct gacttaaata attgttcttc tgggaactaa
      901 atcgaattaa gcttcgattt ctgtaaccat acctgaacca acagtacgtc caccctcacg
      961 gatagagaat gtagtacctt gttctacggc gattgggtga atcaactcaa cgtcgattgt
     1021 cacgttatca ccaggcatta ccatttcagt acctgctgga agttcgattg aacctgtaac
     1081 gtcagtagta cggaagtaga attgtggacg gtagttgttg aagaatggag tgtgacgtcc
     1141 accttcttct ttagtaagga tgtagacttc acctttgaat ttagtgtgtg ggttgattga
     1201 acctggttta gcgataactt gtccacgttc gatttcatca cgttgaacac cacgaagaag
     1261 gacacctacg ttatctccag caagaccttc gtcaagttgt ttacggaaca tttcaacacc
     1321 agtaacaact gctttttgag tttcttcttt gataccaacg atttcgattt cgtcgttgac
     1381 tttaacgata ccacggtcga tacgtcctga agcaactgta ccacgtccag tgattgagaa
     1441 tacgtcctcg actggaagaa gcaatggttt gtcagtgtca cgttctggtt ctgggatata
     1501 ctcatcaact gtgttcatca attccataac gatgtcttcg tatttagagt caccttcaag
     1561 agctttaagt gctgaacctt ggataactgg aagatcgtca cctgggaagt cgtattctga
     1621 caataggtca cggatttcca tttcaaccaa ttcaagcaat tcttcgtcgt caaccaagtc
     1681 aactttgttc atgaagacga taaggtgttt aacaccaacc tgacgtgaaa gaaggatgtg
     1741 ctcacgagtt tgtggcattg gtccgtcagt tgaagctact acaaggatag ctccgtccat
     1801 ttgagcagca ccagtgatca tgtttttaac gtagtccgcg tgtcctggag cgtcgatgtg
     1861 agcgtagtga cgtttttcag tttcgtactc aacgtgcgca gtgttgatag tgataccgcg
     1921 ttcgcgttct tctggagcag catcgataga cgcatagtct ttaggttggt taactgatga
     1981 aggcaagcga cgtgccaaaa cagttgtgat agctgcagtt agggtagttt tcccgtggtc
     2041 aacgtgtccg atagtaccaa tgttaacgtg tggtttacta cgatcgtatt tttcttttgc
     2101 catttgagta aaagcctcca ataaaatata ttttatagat agacagtagg caatacagtc
     2161 taactttcct tactatttta tcaaatttca gctaaattgc aagtgtttta caacgttttt
     2221 gtgaattatt cttgataaaa atttaactaa ctaatagaaa gtactaaata gacttatcct
     2281 tcaaggagtt ttcagcatta tccatccact cacttgctga aaatgtaaac agtctctggt
     2341 ttatatagta aaatgaaaca agaatagggc aaatcgatca ggacagtcaa atcgatttct
     2401 aacaatgttt tagaagttga ggtgtactat tctagtttca atctactata caacctcaaa
     2461 actgtgtttt gaacaacctg cggctagctt cttagtttgc cctttgattt tcattgagta
     2521 taaaattgca gataaaacga taacaatcat aggactcagc agagtcaatg taggtcgaag
     2581 aatagccctc ctaatcgctt attttatagc aaaatgaaat agaaactgaa cattttgttg
     2641 aggaaggtaa atcaattcct cacaatgttt gagaaagaag ggaggactat tccaacttca
     2701 acccactata aagcagactt acaagatagg gaacccatct ccgataatat atagtagaat
     2761 gaaaactgca caatttgatt ggagaattca aaccaatttc taacaatgtt ttagaaacaa
     2821 gggtctatta tttcaactgc aacctactat agcccattga agctggaata gcccactgag
     2881 acttctaaac cactgctgga gaggagtttg tttagagttt ctttcatttc cctaaaaaat
     2941 caaaaagaga gaaccagtct gatcctctct tacttataga tggtgctcac tcaaatgtta
     3001 aaggagctat ttcttagaga taaaggaatt tgaatacagc tactgccgca attgctgctg
     3061 cgataggtgc tactactggt acccaagaat accaccattt tgaatcgcct ttatgctcac
     3121 caagaactga ttttggaagg aaagcatgaa ggagacgtgg tcccaagtca cgggctgggt
     3181 tcaaggcagg tcctgtaggt cctccaagtg atgttaccaa agccataacg aggaatccaa
     3241 gtgccaagtg agccacagaa agtcctgaag cagtgtgtgg agccacctgt gctttaatag
     3301 ccaagtcaga aaaatcaact gtttgtcctg cttctattgc cttttgtttc atgaattgaa
     3361 gcacttcagc accaaagaag tttttagtca aaccaagagc tgcaaagaac aaaacaaatg
     3421 aaccaacaaa ctcattaatc aaaccattga cagttgctgt atagcgactt tcttttgtac
     3481 catggtcaat acttgaaata gttgagaaag ttcccaagat gttatttggt ttttcagttt
     3541 tcaagtagaa tggacggtat gttgccacaa ctaaggcttg gccaaagata gcccccaaga
     3601 cttgcgcgat aatgtaaggt accacttgtg cccaagggaa aagaccgcta actgcaagcc
     3661 ctagagtgaa agcagggttg atgtgattcc cagatacgtt accaaacatc aaggctggga
     3721 tcataacccc cataccataa ccaacagcga tgacgatcca gccactttgg tgacctttcg
     3781 tacctttaag ttcaacgttg gcaactgcac cattcccaag aatgatcaaa atggcagttc
     3841 ccaaaaattc agtggcatac ttcagtgccc atgtgaaatc catttgctag attctcctta
     3901 aaatttttta gatattcctt attttatcaa tttttaccct atttagcaac tgatttctgg
     3961 aaatattttt aaaaaaatag gattcatagt ttcccagttc aacgtacttg taagcgtttt
     4021 tattcttcac gaaagacctc attctcaaaa ccaggaaaaa gcccacatct gtgatctttt
     4081 ccttgttcct agattctaaa atctattatt tttcatcttc ttttttcttg aagaatccta
     4141 atcctagacc agctaacaag gtcatgatac cagcactagc caaggtagca ttagcttctg
     4201 tacctgtgtt tggcaattcc tctctcttac ctgtctcata agtcggaact tctgggtctg
     4261 gattcactgg agtttcagtt tttggagtac ctggttctgg agttggttta tctggtgttg
     4321 ataaacggtc ataccttacc gttatttctt tatcactaga gtctgacgta acttcttgtg
     4381 attcaactgt tggaatatct ggatctttgt acttgtcaat cttaccagat ataacctcgt
     4441 cccagtttcc tgttgtccat tcaccgtagg ttacaactcc cgtgaccttg ttctcagttt
     4501 ttgtacggct taaggttaca ggttgaacaa catcttcttt tacattttgg ttcgtaactt
     4561 tatcaacgta atgaatgata cgcgttatag tcttcgtctc agtagaggtt gctgttttgg
     4621 gaaccactgt ttcctcaaca ttctcacggt agtaatagtc aactgttgca ccgtcttctg
     4681 gtacgcattt gcaggagttg ctaccaaggt gtatgttgtt ttccttgtga taactcggtc
     4741 ttctttgtcc tcagttgttg ttttcccttc aatagttttt gattctgtgg tatactcaga
     4801 acctatcgct aaatcagctt ttataacaga ctctgccaac ttctcttggc taccttcttt
     4861 atagtaattg gctgttactg tagcagtggt tggcgcttcg ctttctctat aaactaaggt
     4921 cactgttcta ccttcgctta caatattccc agttaaactt gcagaatttg tatctgcttc
     4981 tttaaaagta taatattttc cgtcagtagt agtcatgcta ctgagttttt tatctgtgac
     5041 attatagctg gtaccaatca gttgtttttt attggtaatg taggttccgt cactttcttt
     5101 ttctccaatt ccagtatcat ttttcaatga tagcaaacgc ccttgttcat caacatagcg
     5161 aactttcaca ttttctgaga ttagttctgc caattctgag gtttttttct ttttcttgat
     5221 ttcttcggtt attttccctt tctcttcttc gggaatattt agttttggaa tgattttttc
     5281 aacaacggtt cgtgatggtt ccacagtatc ttggatgact gaaaagtcag ctagaattgg
     5341 gagattatac tgaacacggt gactttgagt gtttactcct actctttcat tattctctga
     5401 aaatactcgt acggtataag aaacaacatc ttttcctaat agaacatccc cagtagagaa
     5461 atagccgcct tttcctagtt tgctatctcc agagtccact tctttcctaa tcttatcaga
     5521 tagtttttta ccagtcagta cattcgttcg cacaatccct ttgtctaccc ctacaaagtg
     5581 ggagaacttt ttgaactctt cagaaccaga tctagcccaa ccattattaa gggcatttgc
     5641 ttttgtattt gtattctctc tcaaaggttt ggcgattaga attatattca tcggcactta
     5701 gagttgctgc tatatctgac tcttgaatac caacttcctt actaccattt ctagcggcag
     5761 tatatgtgta tttatctgtt tctacttcta gctgattatc cttaacatga taggtaattt
     5821 tctcctggta taagagtctt cagtagttta tatgctctgt catcatcttt agctttagaa
     5881 gcagctgagt ttagccaagt tggggtatta ggagtatctt tatcagcctg tttcaagaca
     5941 ttattcaagt catttgctaa cctattggtt gtcctcactg tgaaagtttt cttccagtct
     6001 gaatcacttt tattagactt agatatgctc atgaaatcct ggtcaacatt caacacaata
     6061 tcgccttgtt ttttagcatc ttccgttgct tctgcttcaa attgatcatg gagtttttgt
     6121 tgctctggtg tatagttttt ttatttacac gatttaatgt actatttttt attttagtat
     6181 taagaactcc attaatacga tttttaaact ctgcttcaaa aaatccctta atttgttggt
     6241 gcgcaagttc aacattcaaa cctttcttat acaagtcttc attctgaacg atttcggcta
     6301 cacggtgaat ggtttgatcg tataccgtct tctcttaacc agcagtatcc ttagttttaa
     6361 tgactactcg ataggttcct ttagaaccgt tatagtcatc tagttttaaa aaagcgttcc
     6421 aaacattcaa aaatagttgg aacttccctt aataaatccg tcactttctt tttcaagata
     6481 gcccaagctt gctcaatagg attcaaatcc ggtgaataag gtggtagagg taagaaaaag
     6541 tgtttatctt ggatgcagag ttcatccaaa atgttcttgg gatgaaaact agcattgccc
     6601 atgacaataa catgaggtgt cttcaaagca ggtaggagtt gcgttttgaa ccactccaca
     6661 aagaaatcgc ttgtcatgct tttcttgtaa atcatgggag ctataaactc tccgcctact
     6721 tgtcctgcaa caattgaagt tcgctcaaaa cgacgtccgc taatcttttc atagactttc
     6781 tcccctctag gagcccctgc atagggacga tataggtagc ggtcgattcc tgtttcatca
     6841 atatatacga ttggtaaatc ttttaggtta tccaaaatat caagaaactc agcgactttc
     6901 tctgactctt gttccttaaa gctcgtcatc tttttttaaa gtgaccttaa tctgctttaa
     6961 agctgcccat actgaaggaa cagcacaatc aaaatgtgcc gcaatttccc gtaaaaaagc
     7021 atctggatga gcctctacaa aggctttcaa ttcctctaaa ggaatctttc ggtttttgac
     7081 gactcgcttt ttcctctcta tgtgtccttg ttcacgtctt tcttttccca cgtgaagaga
     7141 gttctgacgc caacaccaaa aaacttggct gcctcgacat gactgtgccc ctctttgatg
     7201 gaatctaatg ctcgctgttt aaaatcagta ctatatgcca tagctttatt ataacatgta
     7261 ttttataaac taagctacta tatcaatgtt ttgttatgag aagacttact ttttttactg
     7321 aaattgaatt tttcctcgcc tcaacatcat ataaccccaa aattcaatct gacctggttt
     7381 gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat ataatcaaac
     7441 tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa
     7501 atgggttgat tttgtggagc ttcctgacta tcttcgtcaa gatttggaaa atatggacga
     7561 aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg
     7621 cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg
     7681 attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc
     7741 ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa
     7801 acacggcatc aaatcttacg tatttgaaag ccttcgtcca actccagaac tatcatttgc
     7861 agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc
     7921 atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga
     7981 cgctttgact acttatatcc gtgcaatcga aaccccattt gcagttgaag ttgctgatgt
     8041 ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagttgttg acatagaata
     8101 ccttaaagag gttaaggaca taaacatcaa cccagccttg attgaagaat ttggtaaaga
     8161 catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct
     8221 tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga
     8281 cttctcaact gtaacatcgc caaacccaga aagccaagca gcctttgccc ttgctgaaga
     8341 acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt
     8401 tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg
     8461 tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa
     8521 tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta
     8581 cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga
     8641 attcgaagaa aaacacaacc acacctacat gatgggattt gaagaaagct tcggttactt
     8701 gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact
     8761 tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa
     8821 agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc
     8881 tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaaaag aatggaacgc
     8941 aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac
     9001 tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc
     9061 atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt
     9121 aggggaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag aaatcaatgc
     9181 atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca
     9241 aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat
     9301 ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg
     9361 caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct
     9421 tactgccgta aatttgcagg tgcattgtca ggtgtcgtag ctgaaaccaa agctcacatt
     9481 tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc
     9541 tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt
     9601 tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc
     9661 taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc
     9721 gttttattgt tcctaaaaca gttacatcag tatttcatta cagaacattt taattttgga
     9781 agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca tattcaatta
     9841 tccagattca atcgctatta tcgttttcct agattacaaa aaaactacgt tttgctaatc
     9901 aaaacgcagt ttcagccact attttatctt actgtccttc ttttacttct ttggttgcta
     9961 catcttctcc aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag
    10021 aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa
    10081 aagcttctgt ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt
    10141 ctaaataata gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca
    10201 aatcaatcaa ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat
    10261 tcttcaaaat ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc
    10321 ctaatgtctt tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca
    10381 atacctgctc attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg
    10441 tagcggaata gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca
    10501 aatcccaatc aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag
    10561 ctaaatcaat atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa
    10621 aagtactatc aaatccaata gtaatagact tgttagactg gtactttgac caattatctc
    10681 cactagtttc gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga
    10741 ctaatacaag catccatttt ttcatccatt tttcctccta tttaggttct actttcaata
    10801 atacatctgc gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc
    10861 caagttccct attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg
    10921 cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag
    10981 ccacccgctg cttttgccca ccagatagtg agaaaggata ggactctgcg tgtcctccta
    11041 gtcctaactg ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca
    11101 tggtcttcac aggcgataaa gtcaaatttt ccagaactga tagatgagga aatagttgaa
    11161 aatcttggaa gacaaatccc agtaggttgc gcttctgcaa ttcatccagc tctaaaggtt
    11221 gtccattata aaagatttgc cctgaatcaa tggtttcaag acccgcaagc atacgtaaaa
    11281 gagtcgtctt acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac
    11341 ttagactgaa atcagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt
    11401 ctaacatagc tgccccctat ctataataac tgtacttttt ctcaactttt ttggaaataa
    11461 ttgtcacaat cccaattaaa atcaagtaaa tagctcctgc caagaacata ggaaccagac
    11521 tagcatcgcg gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcgt
    11581 agaccaaaga agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga
    11641 tcttggtcac ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga
    11701 ccttggcagc ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg
    11761 caaagtaagc tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac
    11821 gaatcccaat acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc
    11881 ctcgcataac ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca
    11941 aggcaaaggc aatcaaaacg cccaacggaa tcgaaaatag caagaccagt gcaaagacct
    12001 gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac
    12061 tgcacctcct aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt
    12121 tttgtaaaaa gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta
    12181 cagttctata tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca
    12241 tctggaacca gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat
    12301 tcacgcaaga gatagatata gtgttccaga aattctggat tgtccttcaa atctcctgtc
    12361 aactcttgat aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca
    12421 atcatccact tggtcaaaag attttctggc tcctcactct gcaagtctag aatatcctca
    12481 taacgctcct gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca
    12541 gcgtcttctt ttgcagtaag gagataattt tctgcaccac tagcatcatg caattcataa
    12601 gaaaattgtg aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc
    12661 ttagcgatac gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca
    12721 tactcatagc cttcaaagtc aggagaaatg gtattaagct gcttaaagta gagggtggct
    12781 ttttgatatt cttcttgatc aaaataaaga ctggccaact caaaagctgt taagtcatcg
    12841 tattctaact ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga
    12901 gcataggcaa agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga
    12961 ttatctaact gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac
    13021 tctgccaaac ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc
    13081 tcacgtgcca catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac
    13141 gagacatacc agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt
    13201 tgaccatcct cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca
    13261 attttcaggt aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc
    13321 aactcataca gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc
    13381 ttagttaaat cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac
    13441 ttcctcaccc tctaattcat atagaccact gactacctta taccattcga aaatggctga
    13501 aatgacaacc ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa
    13561 catagatcct gaagttaaca aaacaaagag aacattaata gggtggatgt ttaattgact
    13621 tcccaaaatc aatggagaga caaaacggcc ttcaatagtt tgttctacaa taaagacaat
    13681 cactactttc aaaagcatga ctggaccagc aatcaaaccc aatactaggg caggaagcat
    13741 ggctagaaag ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt
    13801 aaccgcatag cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat
    13861 agccactgtc acttgccctc gaacatagtt ggacaactgt tgattcacat ctgatagaac
    13921 ttgtccaaca ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc
    13981 tttcccatca cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac
    14041 ttgagaagct ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact
    14101 tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa
    14161 atcatctggc aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta
    14221 aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc
    14281 caagccccaa atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg
    14341 attaacctta tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc
    14401 agacaaaatg actggcaaca tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa
    14461 actaatctta cttaaaataa aaagattcaa tcccaataat aaggttacta aaaataccgt
    14521 aattgccttg ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt
    14581 ttgctccata aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata
    14641 actctttttt aaagtgctta catctaattg aatgtcttta atttgcttgt ttttgtgata
    14701 taatagtctt atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt
    14761 atacacgtcg tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc
    14821 tttcaaatct agaacttttt gcagctgagc caagtccaac ctaccttgcc tttgaccagc
    14881 accaacattt atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa
    14941 ctgacgggac tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg
    15001 tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt
    15061 ataaacgcca ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag
    15121 gtccacatga aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact
    15181 atctagtgac ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag
    15241 gaaaattatc taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca
    15301 ttttccataa ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag
    15361 ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca ggtcatttca actttaccgg
    15421 aagcttacga aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc
    15481 tctacgcttc taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta
    15541 gcttagagtt attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga
    15601 cacccgacca aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta
    15661 aacgtaattg tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag
    15721 cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt
    15781 tcattttttc ttatagtcta tttccgacat taatacggtt aatggcacgt tgcaaagcaa
    15841 tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt
    15901 ctgcacgaag tttggcacgt tctgcacgac tgatatcgat atcacgagca cgttctgcag
    15961 agtcagcgac gattgtaatc atatcattgg caatttcaat aacgccaccg tttactgcaa
    16021 tccagttcac gtgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa
    16081 ccgcaatcat attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg
    16141 atacatagct ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta
    16201 actgagccat aggtcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg
    16261 atagaaccta caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt
    16321 tccttaaagc cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat
    16381 tgttccgcaa cgttgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc
    16441 aaggtctttt cttcatcaga aagctcatcc ataccaagga tagcaatgat atcttgcaat
    16501 tcatggtaac gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca
    16561 acgatttcag gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata
    16621 cccaattgta ccaacttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt
    16681 gctggcgctg ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca
    16741 gaacccttct tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt
    16801 ggttggtaac caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc
    16861 tgagtgaaac ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg
    16921 aagtattcag cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca
    16981 ttcatctgac caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag
    17041 taaaggtcat tcccctcacg agtacgttcc ccaacaccag caaatactga aataccaccg
    17101 tgctcttggg caatgttgtg aatcaattct tggattaaga cggttttacc aactccggca
    17161 ccaccgaaaa gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg
    17221 atccctgttt caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta
    17281 tgaattggct gacgctctgc gtcttctgta aaaggagctt ccaaatcaat ggtatctccc
    17341 aaaacgttga agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct
    17401 gtgtccaata cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga
    17461 accataccat ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca
    17521 tttttgtaga cgacaagtgc attattaatc tcaggaagtt tttcccctgc tgcaaacaaa
    17581 acgtctacaa cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat
    17641 tctatataag atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag
    17701 ctggactaga gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt
    17761 aatagccgcc tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc
    17821 attatctgtc gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc
    17881 gataatggca ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc
    17941 ttctcggctg gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc
    18001 caagtcaaca atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg
    18061 gtggttgtag caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt
    18121 tgaaataatc ttacgaactt gatcaaagct aggttggtct gacaagccac gtaattcata
    18181 aagtggttga ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat
    18241 ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat
    18301 agaggaatta taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt
    18361 cttcacagaa cggctaatca acatcggatt agttgaagca ccagctccat taccatgaag
    18421 gatatctgtc aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc
    18481 ttcagagcga cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt
    18541 attttttgtt gaggcgattt ttgttttaat atcatttaga gacactgcca tctgacacct
    18601 ctattcttat tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc
    18661 ttcttctggc aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc
    18721 aaagaaggca tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa
    18781 gaaaccatgt gtcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg
    18841 aacaggttgt ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc
    18901 tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac tcacggtatg aagcaaggtc
    18961 gatacgaagt gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg
    19021 agatacagat gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc
    19081 aaggaagatt tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc
    19141 tcctgcttgt gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga
    19201 aactttagct gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc
    19261 ttcacgacct ggaggacgac gaagcaagag cgacagttca cgataagcta ctgcttgttt
    19321 tgatagatca tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat
    19381 agcaacccca gcataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt
    19441 cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac
    19501 tgttgattct ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt
    19561 caagattgta tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc
    19621 acgttgacca cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg
    19681 ttctgaaaca gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt
    19741 atcagtgtgg atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc
    19801 aatcagactt tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc
    19861 ttcacggata tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt
    19921 ttgagccata ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc
    19981 aaggccatga gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac
    20041 atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc
    20101 gttaattgcc aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt
    20161 tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga
    20221 ctttcatcga tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa
    20281 gggagcaaac gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca
    20341 aatcgatttg tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga
    20401 tttgctctgt gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa
    20461 tcttggaaaa aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa
    20521 aaagaaggca gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata
    20581 cggtcttctt ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt
    20641 acctttactg ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga
    20701 gtgctttatg ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg
    20761 tcaaatctgc gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt
    20821 cttgattggc tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag
    20881 ccttactttg ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc
    20941 taccagccaa ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt
    21001 cagctctgtc aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat
    21061 tagaccatgc aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa
    21121 taaaattacc aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct
    21181 tcaatattaa tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg
    21241 atgcaggaaa taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga
    21301 taccaataaa tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca
    21361 aagatattcc caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata
    21421 ttcatcggta tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga
    21481 cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac
    21541 tgtaaattag cggttggcga actccaccag ttagtcccat cgatcgtttg aatctttgtc
    21601 attaagccaa ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgag
    21661 taatctttca tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag
    21721 acatactcaa gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa
    21781 taaataaaga caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg
    21841 aagataacag gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc
    21901 ttttcttctc gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa
    21961 agttccttca ataaaggcaa cacctaaaaa catcaaacta cgaaactcag aaagcatatc
    22021 tggttggcga gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac
    22081 gcccatacag gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa
    22141 ataaaattta cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat
    22201 tggaagcgtt taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc
    22261 cagaagtctt ctctgggtga cttgtagtcc aagcattttt taggatagtt gttaatccac
    22321 ttttcgatga atgcgacttc tttgggagtc attttcttgg ttcccttagg taaccatcta
    22381 cgaatgagcc tgttgtgatt ctcattagtt cccctttccc aagaggcata gggatgtgca
    22441 taata
//
LOCUS       DAVKAU010000025        22211 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVKAU010000025 DAVKAU010000000
VERSION     DAVKAU010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22211
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.025"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(211..1434)
                     /locus_tag="VWX48_001215"
     CDS             complement(211..1434)
                     /locus_tag="VWX48_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9171844.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1603..2925
                     /locus_tag="VWX48_001216"
     CDS             1603..2925
                     /locus_tag="VWX48_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9171845.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2927..4813
                     /locus_tag="VWX48_001217"
     CDS             2927..4813
                     /locus_tag="VWX48_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU9171846.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            4981..5325
                     /locus_tag="VWX48_001218"
     CDS             4981..5325
                     /locus_tag="VWX48_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9171847.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLVEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5335..6747
                     /gene="lacG"
                     /locus_tag="VWX48_001219"
     CDS             5335..6747
                     /gene="lacG"
                     /locus_tag="VWX48_001219"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9171848.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6817..8496
                     /locus_tag="VWX48_001220"
     CDS             6817..8496
                     /locus_tag="VWX48_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9171849.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPHGKV
                     INDTSAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QPISFVLLSLMLVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(8621..10060)
                     /locus_tag="VWX48_001221"
     CDS             complement(8621..10060)
                     /locus_tag="VWX48_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9171850.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMNNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSIDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10064..11413)
                     /gene="trkA"
                     /locus_tag="VWX48_001222"
     CDS             complement(10064..11413)
                     /gene="trkA"
                     /locus_tag="VWX48_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU9171851.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRITYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11601..12449
                     /locus_tag="VWX48_001223"
     CDS             11601..12449
                     /locus_tag="VWX48_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU9171852.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12464..13012
                     /locus_tag="VWX48_001224"
     CDS             12464..13012
                     /locus_tag="VWX48_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU9171853.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            13019..13321
                     /locus_tag="VWX48_001225"
     CDS             13019..13321
                     /locus_tag="VWX48_001225"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171854.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDRTDEVS
                     SKHGFEVVDETDEVSNHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            13423..15105
                     /locus_tag="VWX48_001226"
     CDS             13423..15105
                     /locus_tag="VWX48_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171855.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEEQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            15090..15920
                     /locus_tag="VWX48_001227"
     CDS             15090..15920
                     /locus_tag="VWX48_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9171856.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            16113..16616
                     /locus_tag="VWX48_001228"
     CDS             16113..16616
                     /locus_tag="VWX48_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU9171857.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      16670..16904
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            17069..17632
                     /locus_tag="VWX48_001229"
     CDS             17069..17632
                     /locus_tag="VWX48_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9171858.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            17646..18272
                     /locus_tag="VWX48_001230"
     CDS             17646..18272
                     /locus_tag="VWX48_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9171859.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFQALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIEQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            18299..18688
                     /locus_tag="VWX48_001231"
     CDS             18299..18688
                     /locus_tag="VWX48_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU9171860.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDRISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            18693..19142
                     /locus_tag="VWX48_001232"
     CDS             18693..19142
                     /locus_tag="VWX48_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171861.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDWHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            19270..19857
                     /locus_tag="VWX48_001233"
     CDS             19270..19857
                     /locus_tag="VWX48_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU9171862.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            20247..21854
                     /locus_tag="VWX48_001234"
     CDS             20247..21854
                     /locus_tag="VWX48_001234"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU9171863.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         6633 a         3762 c         4880 g         6936 t
ORIGIN      
        1 ataaaaatcg ttatttaagt tcagggttat gatgaatgtt tttataataa taaaatgcag
       61 ctagaagaaa agttatttta atataaatca ctcaacatag agagaaggcg gtttcctata
      121 tggaagtcgt cttgttttca tattgtctaa atacgagata tctactacag gttatagttg
      181 atttaaacag gtctatagat ttctaatata ttaaggtgaa ataatatctt gtaatacatt
      241 gctatgttct atgaaaaaag cgacgatagc taatgcacaa gctcctatac ttccacgatg
      301 tttgttgtaa ggtaaaattt caatttctat attacgagta aagggaacga agtggagctg
      361 gtcttggatt ttatccctga cttcatgagt gaaaggttga taattaagca attgactgtt
      421 gatatagatt ttatcagcag gattgatgag gaggagattt gcaatagaag tggctaataa
      481 attgactcct ttatcaattt gttgacgtaa agcggagtcg cctaaattat aagccgttaa
      541 aagggtgtct aaatgaatgt ctttttcagt ctttacaagg ctttttagta cagttagttg
      601 ggaattttta aataataatt gggcgtgttt gattaaccaa gcatccgaaa tatatgtttg
      661 taaacaacct ttttttccac attcacaata ttgcccattc aattcgacaa tggtgtgtcc
      721 aatttctccg atataaggat ttttagaggc tcctattttt tcttttgtga aaaaggaagt
      781 gtaaatacct aatccagcgt gtaggaaaat aaagttatcg ggggtattgt gtggattaaa
      841 aaggtattgt cctatagcca tacaatcgat attatttttt acaataaaag gaaaattgaa
      901 tcttttaatt acatttaata aattaaaaga ttcccatatg gggttgtttg taatgatact
      961 tccggagtct ttgttataat gtccaggtat tgataagcca aatccaagta attttgtttc
     1021 caaagggacg tactctatag ctgtttttat catattggta atggtggaat tgatttctga
     1081 aataggataa tcttcattca aaatttctgt ctcgaaaaga gttttccctt gtaagtcaca
     1141 tagactgaga aagataccta ggacgtttat ttcaatacct ccaacaacat acggaatatt
     1201 atctgtgata gaaatagttt ttctacgtct tccagatccg gaaaactcgc taaattcatc
     1261 accagtttcg tatatgaggg actgttcgct tagctctttt atgatgttag tcgttgttgc
     1321 tggagtaagt cctgtttcat taacaatatc tgtacgggat gttgctggat ttcgatatag
     1381 aaactccagt atagtggctc tattttgtaa aaaggctgat tgttttgtaa tcatttgttt
     1441 cctcctttgg tttattttat attaaacata agaaaaaatc aattaaaatt attattctat
     1501 acaaagaaaa aaatattgta aaaacaacaa aaaaatatat tgacaacgct ttctgttagt
     1561 ggtatattta atttataaaa aataaaaaaa ggagttccgg tgatgaacaa tattttagcg
     1621 tttttagaaa caaaagtcgc tccgtttggt gaaaaagttg gcaaccaacg gcatttgaaa
     1681 gctattcgtg aaggatttat gatggcaatg cctttgattt tagtcggctc tttatttctt
     1741 attctaatca gttggcctca agaggatttt acaaattggc tgaatagtgt tggattgcta
     1801 agtatcttga caactatgaa tcagtcaaca gtagcgatta tctccttggt cgcttgtttc
     1861 ggtattgcct acaggttgtc ggaaggatat ggtacagatg gtccgtcggc agggatcata
     1921 gccttatcca gttttgtatt gatggcacct cgtttttcga gtatggttta tgataaaaat
     1981 ggggagcagg tcaagcagtt atttggcggc gcaataccat tttctagcct gaatgcatct
     2041 tctttgttta tggcgattac tattggattg gttacagcag agatttatcg tatgtttatc
     2101 cagcgcggaa ttacgataaa aatgccaagt ggtgtcccag atgtggtaag taaatcattt
     2161 tcagctcttt tacctggctt tactactttt gttttgtggg ctctggtctt aaaaggtctt
     2221 gaagcggcag gagttgcagg aggtctcaac ggactcctag gtgcaattgt tggaacaccg
     2281 cttaagttaa ttgcaggaac gcttccaggt atgattctat gtgttattgt aaactcattc
     2341 ttttggttct gtggagttaa tgggggacaa gttttaaatg cttttgtaga tccagtttgg
     2401 ttacaattta ctacagaaaa ccaagaagct gtggctgcag gacaaacact ccaacacatt
     2461 attacattac cgtttaaaga tttatttgta tttattggtg gcggtggagc gactattggt
     2521 cttgcgattt gtctcttcct atttagtaag agtcgtgcga ataaaacatt aggtaagtta
     2581 gctattatac cgtctatttt taatatcaat acagctattc tatttacgtt tccaacagtt
     2641 ttaaatccga ttatgctgat tccgtttatt gctactccta caatcaatgc cttaattacc
     2701 tatgtatcaa tggctgtagg attagtaccc tacacaacag gtgtaatcct tccgtggaca
     2761 atgccaccga tcataggagg cttccttgcg acaggagcta gttggcgagg agctctatta
     2821 caagttgttt tgattttggt ttctgtagca atttattatc cattcttcaa aattgcagat
     2881 aaacgcaatc ttgaaaaaga aaaagctact gttggaggga aataagatgg ttatcagagt
     2941 atttgatcag cagaaaaata cttattctag ctttgcctta gaggaattaa gttactatat
     3001 aaatcgggtc tttaagactg acatagaact tgtcgaggag aaggaagcgg atatttttgt
     3061 aggattagtc aataaagagg atagaaaaga ccatgttctt atctcattag acaagggtaa
     3121 ggggagaatt gagtctaata caattgtagg tttacttatt ggaatttacc gaatgtttca
     3181 tgaatttggg gttgtgtata ctagaccagg gcgcggacat gactttgttc cagagttacg
     3241 atttgaagat tttttagata aagagctatc tatagatgaa acagccagtt actatcatag
     3301 gggagtatgt atagagggag cagattcatt tgaaaatata ctagatttca ttgattggct
     3361 acctaagatt gggatgaaca gttttttcat tcagtttgaa aatccctatt cttttttgaa
     3421 acgttggtat gaacatgagt ttaatccata cctaaataaa gaaaaattct caaatgaatt
     3481 agtacaagaa ttgagtgata ggttggataa agaattgcaa aaaagaggtc ttattcatca
     3541 tcgtgttggt catggatgga caggtgaggt tttaggttac tcttcaaaat ttggctggga
     3601 atcaggtctt agtatttcag aggagaagaa accgtatgtc gctgaaataa acgggaaacg
     3661 agaattattt aatacggctc cgattttaac cagtctggat ttttcaaatc cagatgtggc
     3721 ggataagatg gtagaaatta tcaaggatta tgccaagaaa agacctgatg ttaactactt
     3781 acatgtatgg ttgtcggatg ctcgtaataa tatttgtgaa tgcgaaaact gtagacaaga
     3841 attggtttcg gatcagtata ttcgtattct caatcaattg gatagggctt taacgagtga
     3901 gggattagat acaaagattt gttttctgct ttaccatgag ttgctatggg cgcctcagaa
     3961 agaaaaatta gataatcctg aacgctttac catgatgttt gcaccgatta caagaacatt
     4021 tgaaatgagt tatgcagatg tagattttga caattccata cctacgccta aaccttatct
     4081 gcgtaataaa attatacttc cgaattctct tgaggaaaat ttatcttatc tttttgagtg
     4141 gcaaaaaaca tttaaaggag atagtttcgt atatgactat cctttagggc gtgctcatta
     4201 tggcgattta ggctatatga aaattagtca aaccatttac agagatgtat cttatctttc
     4261 taacctacat ttgaacggtt acatttcgtg tcaagaatta cgtgccggat tccctcataa
     4321 ttttcctaat tatgttatgg gggaaatgct ctggaagaag acaagaagtt atgaagaatt
     4381 gattgaagaa tacttttctg ctttgtatgg gtcaaattgg cagtctgttg ttgaatattt
     4441 agaaaaatta tccagttatt cctcatgtga ttattttaat gcaattggca gtcgtcaaaa
     4501 tgatgtttta gcgaatcatt attatatagc ttacaatcta gctgataatt ttttgccaat
     4561 tattgaggaa aatatttcta agttattaaa tagtcaaaag gatgaatgga aacagctcag
     4621 ttatcatcgt gaatatgttg ttaagatggc gaaggcttta tatcttcaag caactggaaa
     4681 aacaaggcaa gctcaagatg aatggagaaa tgtgttgaat tatatccgtg ggcacgaact
     4741 gctattccaa tctaatttgg atgtttatcg tgtaattgaa gtagcaaaaa attacgctgg
     4801 tttccactta taaatcataa gtatagaaaa tgaaccaagg tattcagaga agattgatcc
     4861 taaatattat gaaatttaag gatttttaag atatttaggg tcaactttct atttatatcg
     4921 tagcgaagtc attttaataa tgatgtgtaa aagatggatc aagattgagg aggaagaaag
     4981 atgaaatcaa aagaagaaat aaatatgctt ggttttacaa ttgtcgctta cgcaggagat
     5041 gcaaggtcag atttgatgga tgctttggcg tttgcgagag atggatattt tgaacaggca
     5101 agagaattgg ttgagtctgc aaacgactca atagtgtctg cccatcgaga acagactaat
     5161 ttattagtgg aggaggcatc tggagataat tttgaagtga gttttatcat gattcatggt
     5221 caagatacct tgatgacaac gatgctattg tatgatcagg tcaagttttt tattgatgaa
     5281 tatgaacgaa ttcgaaagat tgaagaacat attggtttgc aatgaggatt agtcatggaa
     5341 aatttacagg ttaaagcctt accgaaggag tttttattag gagctgctac cgctgcttat
     5401 caagtagagg gtgcaactag ggtagatggc aaaggaacaa atatgtggga tgtttatttg
     5461 caagaaaaca gtccgttctt accagatcca gctagtgatt tttattatcg ttacgaagag
     5521 gatatagctt tggcggcaga acatggtttg caggctttgc gtttatctat ttcttgggtt
     5581 cgtatatttc ctgatataga tggggagcct aatatattag ctgttcgtta ttaccataga
     5641 gtctttcagt cttgcttaaa acataatgtg attccgtttg tttctttaca tcattttgat
     5701 tcgcctcaga aaatgttaga aacaggggat tggttgaata gagagaatat tgatcgtttc
     5761 atacgatatg ctcgcttttg tttccaagaa tttacagaag tcaagcattg gtttacaatc
     5821 aatgaactga tgtctcttgc tgcaggtcaa tatataggag gtcagtttcc tccaaatcat
     5881 cattttcaat tatctgaagc aattcaagcg aatcataata tgttgttggc gcatgctctt
     5941 gcagtcctcg aatttcatca attaggaatt gagggagaga taggttgtat tcatgcttta
     6001 aagccaggct atcctattga tgggcaaaaa gaaaatattt tagcagctaa acggtatgat
     6061 gtttataata ataaatttct attagatgga acttttttgg gctactacag tgatgacacg
     6121 ctttttcact tgaatcaaat attggaagct aataattcta gctttattat tgaagatggt
     6181 gatttagaaa ttatgaaaag agctgcacct cttaatacga tgtttgggat gaattattat
     6241 cgttcagaat ttattcgtga atacaaaggt gaaaatagac aagaatttaa ttcaacagga
     6301 ataaaaggac agtcttcttt taaattaaat gctctaggtg aatttgtaaa aaagcctggt
     6361 attccgacaa cagattggga ttggaatatt tatcctcaag ggttatttga tatgttgctt
     6421 cgtatcaaag aagaatatcc tcaacatccg gtcatttatt taactgaaaa tggtacagcc
     6481 cttaaagagg ttaagccaga gggcgagaat gatattattg atgacagtaa aagaatccgt
     6541 tatattgagc aacatttaca caaagtttta gaggctcgag ataggggagt caatattcaa
     6601 ggctatttta tatggtcttt gcaagatcaa ttttcttggg cgaatggcta caataagcga
     6661 tatggtcttt tctttgttga ttatgaaaca cagaagagat atattaagaa aagtgctctt
     6721 tgggtaaaag gattaaaacg gaattaaggt tagcgatttg actgatgttt aatatatttt
     6781 aactatgagc ttaaattttt tacaggagga gtttttatgg ataagttagt cgctgccatt
     6841 gaaaagcaac aagggaaatt tgaaaaaatt tctactaata attatatgat ggctattaaa
     6901 gatggattta ttgctactat gcctttaatt atgttttcaa gctttttgat gattattatt
     6961 atgattccta aaaatttcgg agtagagtta ccgagtccag ctattgcctg gatgaggaaa
     7021 gtgtatatgc taaccatggg agttttgggt attattgttt cagggacagt tgcaaagtca
     7081 ttggctggaa atgttaacag aaaaatgcct cacggaaagg taataaatga tacttctgca
     7141 atgttggcag ccatatgtag ttatctggta ttaactgtaa cgcttgtagt tgatgagaag
     7201 acgggatcta caagtttgtc gacaaactat ttaggatctc aaggattgat aacttcgttt
     7261 gtcagtgcct ttattactgt aaatgtttac cgattctgta ttaagcgaga cattactatt
     7321 catttaccta aggaagttcc tggggctata tcacaagctt ttagagatat ttttcctttt
     7381 tcttttgttt tacttattag tggtttgtta gatattgtat ctcggtttag tttagatgtt
     7441 ccttttgccc aagtatttca acaactattg actcctattt ttaagggggc agaatcatat
     7501 cctgctatga tgttgatttg gtttatgtgt gctttgcttt ggtttgttgg aattcatgga
     7561 ccatctattg tcttacctgc tgttacagct ttacaactga gcaatatgga agagaatgct
     7621 caacttcttg caaatgggca gttcccttat cattctttaa cacctaattt cggaaattat
     7681 atcgctgcta ttggaggaac gggggctacc tttgttgtac catttatttt gattttcttt
     7741 atgcggtcta aacaattaaa atcggtaggt aaagctacaa ttactcctgt tttatttgcg
     7801 gtaaatgaac ctcttctatt tggtatgcct gttattttga atccctatct ttttgtccct
     7861 tttttgatga ctccaccagt gaatgtattt ctaggaaagg tatttattga tttctttgga
     7921 atgaatggat tttatatcca gttaccttgg gcctttcctg gtcccttggg attgttaatt
     7981 ggaacgaatt ttcaacctat ctcctttgtg cttttatctt tgatgttagt tgtcgacata
     8041 ttgatttatt tgccattctg tagagcgtat gatagacagt tactgatgaa agaagatgtt
     8101 gcaagctcaa atgatattat tttagaggag gatacaagtg aaataatgcc tggtgagata
     8161 gatgtaataa aaagtaagga gttgaaagta ctggttcttt gtgcagggtc tggaacaagt
     8221 gcgcaattag ccaatgcaat taacgagggc gctcaattag cagaagttag agtgattgcg
     8281 aattcaggag cgtacggagc tcattatgat attatgggtg tttatgattt aattattctg
     8341 gctccacaag ttcggagtta ttatagagag atgaaggtgg atgcagaaag attaggtatt
     8401 cagatagttg ctaccagagg aatggaatat attcatttaa caaagagtcc aagtaaatcc
     8461 ttacaatttg tattggagca ttaccaagct gtgtagtaag tttttccatc ttttatttga
     8521 gtaaggactt tgcttacaga caggcttgga tttaaaaacg ttcccccttt ttaatataaa
     8581 aatccctctt tcacaattgt aaaaagaggg attttgtatt ttatctctta gaccaagttc
     8641 tcttcataaa gagaaggagg attgggtaaa tctccaagcg gcctgcaatc attgcaaagg
     8701 agaggagaat ttttgagata ggactaaaga ttgagaaact agaagtggtt cctagaatag
     8761 gcccgatatt attgaaacag ctaaagacag cgctggtcac gatcagaaaa tcattgctat
     8821 ctatgctgac aataaagata agggatagca aaatcatagc atagatgaca aagtacttga
     8881 gaatcttatg ctgggtatct ttatcaatca ccgtttgatt cacatggagg gtcaaaacac
     8941 ggtggggcga taggattgac aaaatttggt ttttggcaat ttttgaaagg atgaggcctc
     9001 gaataatctt gagtccacct gcagttgatc cagcagagcc accgattgtc atgaggaaga
     9061 ggaggataaa ctgggagaag aggggccagt tggtaatatc tccatatcca aaaccagttg
     9121 ttgtaatgat gttggaaacc tggaagaagg ccatttcaaa gctctttgaa aaccctgggt
     9181 agaggtagag ggtgttgagg ctaatcaagc ctgtagaaac cagcacgatg accaagtaag
     9241 cccgaagctc ttcatctcca aagaaggcct taacccgacg gagcataagg tagtagtaga
     9301 gattgaaatt taccccaaaa accaaaactc ctatactaac cagataggta atcagtgagc
     9361 taccatagtg ggcaattcca tcgttataga cggtaaatcc tccagttccc gctgtcccca
     9421 tagcaatgac aaaactatcg tagagaggca taccggctag ataatagatg atgacaaaga
     9481 gggaaaagag ggctatgtaa aggagataga ggatctgggc agtgtttttt aatttggata
     9541 caaccttgcc aaaaacagga cctggaacct cagccttcat cacctctagg tggctatttt
     9601 tggcattgtt cataatagca agtgcaaaaa caagcactcc catccctcca atcaagtggg
     9661 taaaacttcg ccagaagagg agggaacggc tgagaaccga aacgtcgttc aaaatacttg
     9721 ctccagtagt tgtaaaccca gaactaattt caaaaaaggc atcaataagg ctggggattt
     9781 gcccagaaaa gacaaagggg agaccaccaa agaaagacca aaggatccaa cagagggcaa
     9841 cgatcaagac tccctccttg gcataaatcc gttgattttt tggcttctgt aaactccctg
     9901 aaccgcctaa caatacgaga atccctatgg tcgaaaagag ggctgtaaag acttggctcg
     9961 attcacggta atagacagcg atagccacag gaaccaagag gagaacagct tcaatcaaaa
    10021 gtaactttga aaggaggtaa cgaatcatac ttttattcat ttcttacctc gcaatcaagt
    10081 cataaatctt ggtgatgttt ggcaacaagg ttgttactag gagcttgtct ccaacttcca
    10141 acatatcctc cccagttggg aaaatagtct tgccctttcg aataatggct gcaataagaa
    10201 cccctttttt caatttcagt tgagaaagag gtttggcagt cattttattg gcttccttga
    10261 tatggaattg cagggtttcg atttggccat tggctagatg gtgcatggct tgaaggtctg
    10321 aatactgggc attaactcga ccacgaataa agtgcataat cgtatctaca gcgatgcttt
    10381 taggtgtgat gatacttgaa aaatcaggcg cattgataat ctcgaggaga ctggtacgat
    10441 tgaccttagt aatatttttc tgtacaccta ccctgtcaag gaacatagat gtaatcagat
    10501 tttcctcatc gactcctgtt agagtcgcaa cggcatcata gtgttgagca ctttcttcca
    10561 gcaggatatc ttttgcggtt ccatctcctt gaacgatgta gagatttggg aatttctcgc
    10621 taaagaagct ggcgatttca ggattgattt caatgacttt tgtatcgata cgactatctt
    10681 tgagaatacc aagtagataa taggtaattc tacctgctcc aacgatgaga aggctcttca
    10741 cggcgcgtga tttaaaataa ttatggaaga gtatcatatc gacacggtta ccagtgacaa
    10801 agattctatc tttatcctgt acagtcatgt caccgcttgg aatgataatt tgatgatccc
    10861 tctctatcgc acagacaatg acattaccaa attttttacg aaaatcagaa atgggcattt
    10921 ggcaaagacc gctggtggac ttgacgacaa attccatgag gctaacgcgt ccaccagcaa
    10981 agcgttcgac agacagggcg ttggggaagt caatgatatt cgcgatagcg cgggcagcca
    11041 agagctcagg attaacgata agagaaaaac cgagaatatt cttttccttg aaataagagt
    11101 tagaatattc agggttccgc acccgaacga tagtttcttt agctcccatt ttcttggcta
    11161 gaactgctgc aatcatgttg acttcatcgt gctcagtcag ggcgataaag atatcacaat
    11221 cttggacgct ggcttgctca agaatggcaa aatcggcccc gttaccaagg ataccaatga
    11281 tatcaaagcg actgacaata tgattgagaa cagcttcgtc ttgctcaatc agcaaaacat
    11341 catgcttttc tgcaaccaag gagcgacaga gggcaaaacc aacttttccc cctccgacaa
    11401 ggataatttt cataataaaa cctacttttt catgatgtaa ctatcatacc ctttttcaag
    11461 aaaaaatgca cctactagct aataacaaga gcttttagtg aaaattcgct ataaggtaaa
    11521 actataccct aaccaattga aatagctatt agcgactttc tctgaaatat ggtatgataa
    11581 aggatataca aggagataaa atgaataata atttactggt attacaatca gactttggtc
    11641 tggttgatgg tgcggtatcg gctatgattg gagtggcttt agaagagtct ccaaccttaa
    11701 aaatacatca cttgacgcac gatatcacgc cttataatat ttttgagggg agctatcgtc
    11761 tctttcagac ggtggattac tggcctgagg gaacgacgtt tgtatcggtt gttgatccag
    11821 gtgtcggttc gaaacgtaag agtgtagttg ccaagactgc aaaaaatcaa tacattgtca
    11881 cgccagataa tgggacgctt tcctttatca agaaacacgt tggcattgta gccattcgtg
    11941 agatttctga ggtggccaat aggcgtcaaa acacagagca ttcttatacc ttccacggtc
    12001 gtgatgtcta tgcctatact ggtgctaaac tggccagtgg tcacattact tttgaggaag
    12061 tagggccaga gctcagtgtg gaacagattg tagagcttcc agtcgtagcg accatcatag
    12121 aagatcatct ggtgaaggga gccattgata ttctggatgt gcgtttcggt tcgctttgga
    12181 cctctatcac acgggaagaa ttttacaagc tggaaccaga atttggtgat cgttttgaag
    12241 tgaccatcta tcatgctgat atgctggtct atcaaaatca ggttgtctat ggcaaatcat
    12301 ttgcagatgt gagaattggg caacccatcc tttacatcaa ctctctctat cgtttaggtt
    12361 tggctatcaa ccaaggttcc tttgccaagg cctataatgt aggtgtcggt tcatcttgga
    12421 ccattgaaat aaagaaaata gaaggataaa ataggagaat agtatggaaa tcaaatttac
    12481 aattaaacaa gttgttgctg tcggaattgg cgctgccctc tttgtcgtca tcgggatgat
    12541 caacattcca acccctgttc caaatacaag catccagctt cagtatgcgg tacaagcgct
    12601 actttctatt atttttggac cgattatcgg tttgcttgtc gggttgattg gtcatgcaat
    12661 caaggactct cttgttggtt atggtctatg gtggacttgg attatcgcta gcggactctt
    12721 tggtttagtt gtgggacttt ttagaaagta cgttcgcgtg atcaatggtg tttttgactg
    12781 gaaagatatt cttattttta acctcattca actacttgca aatgcccttg tttggggtgt
    12841 cttggcacca cttggagatg ttgtgattta tcaagaagcg gcagaaaaag tatttgcaca
    12901 agggattgtt gcgggaattg ccaatggtgt atctgtagct attgcaggaa ctcttctctt
    12961 acttgcctat gcaggaaccc aaactcgtgc aggaagtttg aaaaaggact aatactcaat
    13021 gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaaacagt gttttgagat
    13081 tgtggataga actgacgaag tcagctcaaa acatggtttt gaggttgtgg atagaactga
    13141 cgaagtcagc tcaaaacatg gttttgaggt tgtagatgaa actgacgaag tcagtaacca
    13201 tacctacggc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt ataaaatgat
    13261 ggggaaggct gggcaactag tctttttcga tgtttataga ttagttaggc aagtaagcta
    13321 ggataggaat ctttttggcg ctaagatttt aagagaagag actgcaagaa gggcttgatt
    13381 tatgataaaa tagaagtcta agaagcgaat gaagagagta agatgaaaga agctataatt
    13441 gagtggaagg atttctcttt ccggtatgaa acacaacaag aaccgacctt gcaagggata
    13501 gacttgacca tttacaaggg agagaaagtc ttaattgttg gaccatctgg atcaggtaaa
    13561 tctaccttgg gtcagtgttt gaatgggatt attcccaata tttacaaggg tcagacatat
    13621 ggagaatttt tgataaaggg tcaagtagcc tttgatatga gcatctatga taagtctcat
    13681 ctggttagca cagttttgca ggatacagat gggcagttta ttggcttgtc tgtggcagaa
    13741 gatttggcgt ttgctctgga aaatgatgtg acagccctag atgagatgaa aggtcgtgtt
    13801 tataaatggg ctgaaaagct ggaccttctt cctttactgg atcagcgtcc tcaggatttg
    13861 tcaggtggac aaaagcagcg agtcagtctg gctggtgtct tgattgatga aagtccgatt
    13921 ctcttgtttg atgagccact cgccaatcta gatcccaagt caggtcagga tattatcgaa
    13981 ttgattgacc agattcataa ggaagagggg acgacgactc tgattatcga gcaccgtttg
    14041 gaggacgttc tgcatcgccc tgtggatcgg attgtcttga taaacgatgg tcgtatcctt
    14101 tttaatggga gccctgacca gttgcttgcg actgatttat tgactcaaaa tggaattcga
    14161 gaaccccttt atctaaccac tctccgtcaa ttaggtgtgg acttagtcaa ggaagaacaa
    14221 ttagcagatc tggataactt gtctatctca aaagggcaag tccagttaca gacggaactg
    14281 gtaaaagaaa ccccagaatt gcagtcactc tttagactag aggacgtgtc tttttcttat
    14341 gatgatagac cgattttaaa atccctacat ttagatatta aaaagggtga aaagattgct
    14401 attgtcggaa aaaatggagc agggaaatca actctagcca aggctataag tagctttatt
    14461 cagacggaag gacgctatct ttgggaagaa caggatataa aaggcgattc tgttgcagag
    14521 cgggcggaac gagtaggcta tgtgctacaa aatcctaatc aaatgatttc aaccaatatg
    14581 atttttgatg aggtggctct agggctccgt ttgcgaggtg tggatgagaa ggaaattgaa
    14641 acgagagtct atgaaacctt gaaaatctgt ggactttatg aattccgtaa ttggcctatt
    14701 tctgccctgt catttggtca gaaaaaacgt gtcaccattg cttcaatttt ggtcttagga
    14761 gctgaaatta ttctcctaga tgaaccgact gcaggtcaag atcagaagaa ctatactgag
    14821 attatggaat ttctcgaaga gttacatcaa aaagggcata ccattgtcat gattacccat
    14881 gatatgcaat tgatgctgga ttattcagac cgggtccttg tcatggtgga tggagaattg
    14941 attgccgata ctgttccagc cagtctgttg agcgatcctg agctgttagt aaaagccaat
    15001 ctaaaagaaa cctccatctt taacttggct aagaaactag atgtggatcc actggattta
    15061 acggcatttt acaaagaaag gagagaggga tgcaagctaa attaatcggt taccagcata
    15121 gagatactgt gattcatcgc ttgtcaggag ctgggaaact tctctttttc attctggtat
    15181 cattggcggc catgattagc tatgatacca gaatgctctt gctgattgcc atcttttcag
    15241 tctttctcct ctatttatca gaaattcgct ttaaagatgt ttcctttgta gccgtttttg
    15301 cgacggtatt tgccgtttta aacgttttga tggtctatct cttttctccc gagtatgggg
    15361 ttggacttta tggagagaga agtgtgattt ggcagggaat cggtgtctac actctaacca
    15421 gccaggagct cttttatctg ctaaatttgg ccattaagta tctttgcacc attcctctgg
    15481 ctattatctt tttgatgaca acccatccta gtcagtttgc ttccagttta aatcaaattg
    15541 gtgtgcccta taagattgct tattctgtca gcctgacctt gcgctatatt ccagatttgc
    15601 aggaagaatt ctttactatc aagatgtctc aggaggcgcg tgggatggaa ttatccaaga
    15661 aagcttctct tatgcaacga atcaaaggca atctgctcat tattacgccc ttgattttta
    15721 gctcgctaga acgcattgat accattgcga ctgccatgga gcttcgccgc tttgggaaag
    15781 agaaaaaacg cacatggtat agttatcagg ccttgaaaaa aggagactat attaccttgc
    15841 tcttggcaac cttgttttta gtagttagtt tactacttat cttgcagaat cagggacgat
    15901 tttacaaccc ttggaaatag cttgaaaaaa ttgaaaaaat caagtcattt ctattgacaa
    15961 tgattctgaa agtgttatac taagaaagta gtttcgctga tttacttcaa acctgttgtg
    16021 aggtaagtta acgatgcctt aaccacgctg tttgctgagc ttgactccgg gcagtgtggc
    16081 tatttttttg caatggtgaa aggaagcaag tcatgacaaa tcacattgta ttatttgaac
    16141 ctcaaattcc acaaaataca ggcaatatcg cgcgtacttg cgctgcgacc aattctcccc
    16201 tccacatcat caagcctatg ggctttccta ttgatgaccg caagatgaag cgggctggat
    16261 tggattactg ggataagcta gagatttatt tttacgagag tttagaagat ttcatatctc
    16321 agatgaaggg aaaactctat ctgatttcga aattcgcgga aaaaatctat tctgaggtgg
    16381 atttatcgac tgacgaggac cattattttc tctttggacg tgaagacaag ggcttacctg
    16441 aagattttat gcgagaacat cctgagaagg ctctccgtat tcccatgaat gatgaacatg
    16501 tccgcagtct caatgtgtct aataccgtct gcatgattgt ctatgaggct cttcgccagc
    16561 agaactttgc aggtcttgag ctcgtccata cctatgaagt ggataaattg aaataaaaaa
    16621 tgaaaatgaa caaaatgctt gcgcttgcaa gcgttttttg ttatgataaa agagtcttca
    16681 gggcagggtg tgattcccga ccggcggtga ctttaactag gaaatgatct tttcctttta
    16741 tactttgttg acaagctttg cctaaccaga agttatgcct acagcttgtc gcctagtcta
    16801 aaagaaaaat ctctatttct ttctctttaa agaagtccgc gagcgcaagc tgatgtggtg
    16861 agattccaca accgacagta tagtctggat gggagaagac gaaagaatag ctttgtctgt
    16921 tttgatagat ttatagccgg attgtaacca cttgctttgt ttttctttaa tagagtaaga
    16981 gggaactttt gggatataaa aagtgagaat agatagagga atcctttcca acttcttctg
    17041 attttataga aaattggagg aacctgttat gacaaacaca cgtcgacttt cgaccattgc
    17101 aattctatca gccatctcat ttgtgctgat gtactttgac tttccgcttt taccagcggc
    17161 atctttcctc aagatcgaat ttagtatctt gccagtcctt gtgggtctgg tggtcatgga
    17221 tttgcctgct gctctaggag tgctcttgct tcgctcactc ttgaagttgc ttcttaacag
    17281 ccaaggagtg aatacttaca ttggtttgcc gatgaatatc gtagctttgg gagtttttgt
    17341 catcgtattt gctttgattt ggaaaaagga acggacaacc cttcgtttcc tactaggctc
    17401 tctagctgga actattggtt taaccttggc catgttggtt ctcaactatg tttatgctgt
    17461 tcctttgtac gctaagtttg ctaactttga tattggaaaa attttgggac tttccaacta
    17521 cctaatgacc atggtattac cttttaactt gattgaaggt gttatctttt ccgtttcatt
    17581 ctggttgttg tacgtccttt tgaaaccaac cttaaaacac tatgaaagat aaacaaacat
    17641 ttttaatgaa gggcagtttt gcccttttac ttttcgttat tcttggctat atggtcaaat
    17701 tttaccctga aatgttggtc aattttgacc aatcgattca gactgccatt cgaggagact
    17761 taccagatta tttgactatt ctttttcaag ccctcacacg tctgattgat atcccagtga
    17821 ttatcacttg ggttgtcatt acagcttttg tcttttatcg taagcgatgg aagatagaaa
    17881 gtttcttcat gctgggaaat ctggctttgg caggtctttt aatcgtgacc tttaaaaata
    17941 tctaccagcg cccacgacca gctattttac atctggtgga ggagaaggga ttttccttcc
    18001 caagtgggca ttctctagct gtaacgctga tggtagggac tttgattgtt attcttagtc
    18061 agcggattaa agatcaggtc tggagaaaaa tcgaacaaat cgtccttggc ctctacctag
    18121 tcagtgtgct ggtatcaaga gtctatctgg gagttcatta cccatcagac gtccttgcca
    18181 gtctctgtgt gggcttggga gtcctgttta tcgagtttcc cttttatgac aagctccgct
    18241 tccaatggcg atttaaaggc aaacagaagt gagtatcgaa ttcccttgag agaaagaaat
    18301 gaaagtcaat atagcagatc ttcatccgac tcaactatat ttatcagaaa agaagttgca
    18361 agatattcag atgctttacc agtcggcaga aacaatccaa gtcgatcgaa tcagtattct
    18421 tgcctttgga gattgtttgc tgattacaga tgggcatcac agggcttatc aggctttatt
    18481 ggcaggtcgg gatacgattt ctgctgagtg ggatagagat ggtggtgatg aactatatca
    18541 tctctatgcg caagcttgcg aggaaagaaa gatttactct gtttttgatt taaaagatcg
    18601 tatcctagct caagatgggt atgaagcaaa atggtataac tggtgtgatg gttttaatca
    18661 agcagcaact cttttgttga aaaggtagtg cattgtgttt tgttccttat tataaggtca
    18721 atcattgtga ggaagctttt gcttggtatc aggatgtgaa cttggtttac ctcgtagatg
    18781 gggtgaagct tccttacagt caagcgacct tggaagccat gtattcctat ttggattggc
    18841 atggtgagct tttttggatt gaagtcaagg agaagggaga atggtttcca attggggata
    18901 ttacactatc tcaggataat ctccccattg tgattgggaa ttccgcttac caacatcgag
    18961 gacttggaaa aaagattcta agtgctttga ttgaattggc tcgagtaaaa ggatggaaag
    19021 aattgagagt caaggaaatc tacacctaca atcatgcttc taggaggtgt ttcaagtcgc
    19081 ttggatttgt ggaaaatgga gcaacagaaa aaggaaggag ttttatattg gaattagtct
    19141 aatcctgcca ctttctcccc cttaaccttt gactattccg caaaattatc gtaaaataaa
    19201 gagtaaatga taaaatgagg tcagagtctg ttcgctctga caatagtagt ataaatgagg
    19261 agaaacgctt tggaattaga agtatttgct gggcaagaaa aaagtgaact atctatgatt
    19321 gaggtagcgc gtgctatctt ggaacttcgt ggtcgcgatc atgagatgca ttttagcgat
    19381 cttgtaaacg aaattcaaaa ctaccttgga acatcaaaca gcgatatccg cgaagctttg
    19441 cctttgttct acacagagtt gaactttgac ggtagcttca tctcacttgg ggacaacaaa
    19501 tggggtcttc gttcatggta tggtgtggac gaaatcgacg aagaaatcat cgctcttgaa
    19561 gaaaatgacg acgatgaagt agcaccaaaa gctaagaaaa aacgtgtcaa tgcctttatg
    19621 gatggtgatt cagatgccat tgactacaat gcagatgatc cagaagacga agatgcatac
    19681 gaagcagatc cagctctttc atacgatgat gaaaatccag atgatgaaaa aaatgaagtg
    19741 gaagcttatg atgcagaaat caacgaaatc gctccagatg acttgggaga agatgtggat
    19801 ctcaacgaag acgacgacga gttttcagat gacgacgctg aaaccagcga ggaataagag
    19861 ttagctattg acaattatcc tatttttagg tatcatattg tttgggcacc tcttttagag
    19921 gtcggggctc cctagttctt agggagctat ttttgttttt tcaagaagtt atcttcttgt
    19981 attttatact caatgaaaat caaagagcaa gctaggaaac tagccgtagg ctgctcaaaa
    20041 cactgttttg aggttgtaga taagactgac aaagtcagga acacatatct acggcaaggc
    20101 gacgttgacg cggtttgaag agattttcga agagtattag ttgtgaatct ggtgcagtcg
    20161 tcccagatta ttcttattag tagggtcttg ttttctatat cccctcgtag ttaacaagac
    20221 cttgagcatt ttagaaagag gaatctatgt ctacgaaata tatttttgta actggtggtg
    20281 tggtatcgtc tattgggaaa gggattgtgg cagcgagtct aggccgtctc ttgaaaaatc
    20341 gtggtctcaa agtaaccatt caaaagtttg acccttatat caatattgat ccgggaacca
    20401 tgagtcctta ccagcacggg gaagtttttg tgacagatga cggagctgag acagatttgg
    20461 acttgggtca ctatgaacgt ttcatcgata tcaatctcaa caaatattcc aacgtgacaa
    20521 ctgggaaaat ttacagtgaa gttcttcgta aagaacgccg tggagaatac cttggggcaa
    20581 ctgttcaagt cattcctcat atcacagatg ctttgaaaga aaaaatcaag cgtgccgctc
    20641 taacgaccga ctctgatgtc attatcacag aggttggtgg aacagtagga gatatcgagt
    20701 ccttgccatt cctagaggct cttcgtcaga tgaaggcaga tgtgggtgcg gataatgtca
    20761 tgtatatcca tacaaccttg cttccttacc tcaaggctgc tggtgaaatg aaaaccaaac
    20821 caacccaaca ctctgtcaaa gaattgcgtg gcttgggaat ccaaccaaat atgttggtta
    20881 ttcgtacaga agagccagct ggtcaaggaa ttaaaaataa actggcccag ttctgtgatg
    20941 tggcaccaga agccgttatc gaatcgttgg atgttgaaca cctttaccaa attccactga
    21001 acttgcaggc acaagggatg gaccaaattg tttgtgatca tttgaaatta gacgcaccag
    21061 cagcggatat gacagaatgg tcagccatgg tggacaaggt catgaacctc aagaaacaag
    21121 ttaagatttc ccttgttggt aagtatgtgg agttgcaaga tgcctatatc tcagtggtcg
    21181 aagccttgaa acactctggc tatgtcaatg atgtagaagt taaaatcaat tgggtcaatg
    21241 ccaatgatgt gacagcagag aatgtagcag aactcttgtc tgatgcggac gggatcatcg
    21301 taccaggtgg ttttggtcaa cgtggtacag aagggaaaat ccaagccatc cgctatgcgc
    21361 gtgaaaatga tgttccaatg ttgggagtct gcttgggaat gcagttgaca tgtatcgagt
    21421 ttgctcgtca cgttttaggt cttgaaggtg ccaattctgc agagcttgca ccagaaacaa
    21481 aataccctat cattgatatc atgcgtgatc agattgatat tgaggatatg ggtggaaccc
    21541 ttcgtttggg actttatccg tctaagttga aacgtggctc taaggctgct gctgcttatc
    21601 acaatcaaga agtggtgcaa cgccgtcacc gtcaccgtta tgagtttaat aacgccttcc
    21661 gtgagcagtt tgaggcagca ggctttgtct tttcaggagt ttctccagac aatcgtttgg
    21721 tagaaatcgt ggaaattcct gaaaataaat tctttgtagc ttgtcagtat caccctgaac
    21781 tgtcaagccg tccaaaccga ccagaagaac tctacactgc ctttgttact gcagcggttg
    21841 agaacagcaa ttagcaaaat cagaaccttt gagaaaaatc tcagaggttt tttgcatacg
    21901 atgatattgc agtatatctg aggtaggggt cctctgtatg tacctgctac cgttgaaatc
    21961 aatagcgact ccctcttgcc ctgtgctagt gaatggattt atcagtatat tgaaatgaaa
    22021 taaaatttga acaaattaat tcggaaagcc aaatcaattt ctagcaaagt tttaggaact
    22081 ggattgtata gtgaattgaa ataagatgtg aacatctcta tcagaaaagt caaattaatt
    22141 tatagaaata ttttagcagt caagatgtac tgttatagat tcaatacatt atactttttt
    22201 aatttaattc a
//
LOCUS       DAVKAU010000026        21881 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVKAU010000026 DAVKAU010000000
VERSION     DAVKAU010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.026"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            382..567
                     /locus_tag="VWX48_001235"
                     /pseudo
     CDS             382..567
                     /locus_tag="VWX48_001235"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1179..1463
                     /locus_tag="VWX48_001236"
     CDS             1179..1463
                     /locus_tag="VWX48_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171864.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            1456..1694
                     /locus_tag="VWX48_001237"
                     /pseudo
     CDS             1456..1694
                     /locus_tag="VWX48_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1790..2008
                     /locus_tag="VWX48_001238"
     CDS             1790..2008
                     /locus_tag="VWX48_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171865.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(2380..4704)
                     /gene="pflB"
                     /locus_tag="VWX48_001239"
     CDS             complement(2380..4704)
                     /gene="pflB"
                     /locus_tag="VWX48_001239"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU9171866.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            5053..6114
                     /gene="dinB"
                     /locus_tag="VWX48_001240"
     CDS             5053..6114
                     /gene="dinB"
                     /locus_tag="VWX48_001240"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU9171867.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMNISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(6261..7106)
                     /locus_tag="VWX48_001241"
     CDS             complement(6261..7106)
                     /locus_tag="VWX48_001241"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU9171868.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            7362..8143
                     /locus_tag="VWX48_001242"
                     /pseudo
     CDS             7362..8143
                     /locus_tag="VWX48_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8522..10411)
                     /locus_tag="VWX48_001243"
     CDS             complement(8522..10411)
                     /locus_tag="VWX48_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU9171869.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPMTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            10549..12114
                     /locus_tag="VWX48_001244"
     CDS             10549..12114
                     /locus_tag="VWX48_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9171870.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWGLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            12114..12854
                     /locus_tag="VWX48_001245"
     CDS             12114..12854
                     /locus_tag="VWX48_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9171871.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFSNPKEDRTKEFLQRYLK"
     gene            complement(12963..13178)
                     /locus_tag="VWX48_001246"
     CDS             complement(12963..13178)
                     /locus_tag="VWX48_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171872.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(14049..15299)
                     /gene="ilvA"
                     /locus_tag="VWX48_001247"
     CDS             complement(14049..15299)
                     /gene="ilvA"
                     /locus_tag="VWX48_001247"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU9171873.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(15349..15705)
                     /locus_tag="VWX48_001248"
     CDS             complement(15349..15705)
                     /locus_tag="VWX48_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9171874.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(15943..16179)
                     /locus_tag="VWX48_001249"
     CDS             complement(15943..16179)
                     /locus_tag="VWX48_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171875.1"
                     /translation="MLADQNKADWSYDENTVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHFPFERAGATKSARYIAKWILRNKKH"
     gene            complement(16286..17308)
                     /gene="ilvC"
                     /locus_tag="VWX48_001250"
     CDS             complement(16286..17308)
                     /gene="ilvC"
                     /locus_tag="VWX48_001250"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9171876.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVTEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(17374..17850)
                     /gene="ilvN"
                     /locus_tag="VWX48_001251"
     CDS             complement(17374..17850)
                     /gene="ilvN"
                     /locus_tag="VWX48_001251"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU9171877.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(17843..19543)
                     /locus_tag="VWX48_001252"
     CDS             complement(17843..19543)
                     /locus_tag="VWX48_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU9171878.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(19744..21411)
                     /locus_tag="VWX48_001253"
     CDS             complement(19744..21411)
                     /locus_tag="VWX48_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU9171879.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(21414..21779)
                     /locus_tag="VWX48_001254"
     CDS             complement(21414..21779)
                     /locus_tag="VWX48_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9171880.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
BASE COUNT         6729 a         4676 c         3901 g         6575 t
ORIGIN      
        1 tttttgtttt tacaattctc cttagttaaa tcttgtttaa tatatgtttt acatatagta
       61 tttagcgcca catagtactg aactctctcc aaaaacggtt attcctcttt gaatagggcg
      121 ttatcacaag aaaagcatct ccacgtttca acttcatatg gctcaaaaac aatcaattga
      181 tgctaaaacc tgtacctaga tgtttcggtt cataaaacca tgaaactgta aaagtggatg
      241 aaattgatag cgatagtcaa atcaagaggc atcataactc taaaaagtca caatatataa
      301 gctcatcctc ggaaaaatat cattctaatt gttgaaatgc ctacatgaaa agaaacgtca
      361 aatactcatg aaacaacgaa tacaggtatc aaaactatga caaaacaagt ccctaaattt
      421 actaaagaca ctgctcaact ttacacctgt aaatggttgt tgtataataa agttacaaag
      481 atgtacgacc acactgttgt aaatcatagt gttcgcgaat atattactga tagcatttct
      541 acaaatacaa ttgaagagac tggataggct ttaaacgaaa tatgtcagtg ttttggcatt
      601 cctagtcttc atatcattta aagaattgta tagacaaaat ttttttccaa tacagacact
      661 cgtaacaact gcttcatttt tctaccaaca tatttaggaa caggataaga tacaagaaga
      721 ttaatccata gctcagttct ataccaatct aagacaaata agctaaaaaa cgattgataa
      781 taagcaaata gattccaaat tttctctatc tgctcatttt aataaacaat actagtgtaa
      841 ctatccttcc agtcagaaac ttgtcaaatc acaccgaaaa ctcttctaaa atttatctcg
      901 ttaggcaatc aagcaaaaac tcgacgatag tacaaacatt atcatacaga attgacttcc
      961 taaattatat actttagtaa ggttttcgga taagaaaaaa ggttcatttt acatttctaa
     1021 acattctttt ctaagatgaa aaacagaatt tttcgattgt gatttaaagc aacaagaaga
     1081 ttttcagtat catcctatag atacgagcta attaagaaaa actacatttt tgaatataaa
     1141 ctacaataat ataaactaaa ttttatagga ggaagacaat ggattggtac gattatatga
     1201 tacaggcatc caaacaatca caattcaacg caagccattg gtttcgctat ttgcgaaaag
     1261 ttatttttga agactattct tatttaacaa accaagatgt agaaaagttg ctagactcca
     1321 aagaactaac ccgttttcaa aaaattagct tgaagtatgc ctttcaagag catactccaa
     1381 ctcataaata tgtgatttca ttaaataaac ctgctaagtt aaccaatgtt caaaaattga
     1441 tggagaaata caaacatgga taaaatgaaa ccggtcttcc aagccctaaa taagaaatta
     1501 attcaggaaa atctgacttt aacaattatg gttatgtctt agaatatcat ggtttacgtg
     1561 ccacacaaga tgttgatgct ttttatgacc aaaatcagaa aatcaatgaa attattgctc
     1621 gtgtaggaaa acagtttaat cttaacatcc acgaagagtt atggctcaac aatcatgttg
     1681 caaagcaaat atgaacaaac aacctccctt aagtttatgc gaatccttgt actcatttga
     1741 gaatctgacc gttttagtag tccctattga gtatgtgtta ggaatgaaga tgatgagtat
     1801 cagagagcag gatttgcaag atattggtgc aattattaaa tacaaaaact ttcattcacc
     1861 attcgatacc tttaaatatt taaaagacat gggatttgat actattgacc tctctgttct
     1921 attagaaggt tttagttatg cttatggtat ggattggtta gaaaaatttt ttaaagaaaa
     1981 tcaagataaa cttcgcgaat tttattaaca gtatcaaaca agatgattgt caattagcca
     2041 gtcgtcttat ttttatgatg aaatgaaatg aaataaaatc ggaacaaatc acttagagaa
     2101 ttccagtcaa tttctagcac tgtttgagcc gtttcagcgg actatagtaa aatgaaataa
     2161 gaataggaca aatcgatcag gacagtcaaa tcgatttcta agaatgtttt agaagtaaag
     2221 gtgtactatt ctagtttcaa tctattatat ttcagattcg gtccactatt ccttcccaaa
     2281 aacattgcat attgcgccga aggaattgct catactatcc caagcacaaa accctcagtc
     2341 gtttgaccga gggttccttt ttattattca agaacttgat tagctcaatg catccaaggc
     2401 gtcatccatt gaaagaactt cgtggaagac acgttgtgtc aattcagttt tttgttctgg
     2461 agtgaggtat ttagtgttta cacagtatcc agagatacgt acgataacgt cttcgcctga
     2521 catgattttt tcgtaaacat cgttcaagtc cataacgttc aagttaacgt gttgtccacc
     2581 gttttcgaag taaccatcaa ggattgttac caagttatca acttgttcat cacgagtctt
     2641 accaagagcg cgaggtgata cttgtgtagt caatgagata ccgtcagctg cataactaaa
     2701 gtcaaggcta gaaagtgagt tcaagttttg caaccaacca cctttagctt tgttagatgg
     2761 gttagcacct ggtgagaaga attcaagttt agacaagttc acagaaccat cttcgttgag
     2821 gtatacacct ttgtgaactg gtgagttacc agtttgttta gagtaagcaa cgttagatgt
     2881 gattgtcaaa agtgatactg tagcttctgc atctttgtat agtttgtggc tacgtagacg
     2941 agttgtgtaa gcttcgatca accattctgc caattcgttt gaacgtgggt catcttcacc
     3001 ccagcgtggg tagtcaccga ttgtttcgta atcgtagatg tagccatctt cgtcacggat
     3061 tggtttaact gtagcgtatt tgatagctga caatgtatca acagtgttag caaatccaca
     3121 gataccgaat cccatgttgg cacgttgttt agttggcaag aaggccattt gaacagcttc
     3181 gtagttgtac ctatcagtca tgtagtggat gatgttcaag gcatctacgt aagtgtcagt
     3241 caaccagtca agagattttt caaagttcgc tttaactgat tcaaattcaa gaacttcgtc
     3301 acggattggt tcgatatcaa atactttgta gtctttgtga acatcgtcgt aaccaccatt
     3361 caaaccagta agaagggctt taagaacgtt tacacgagca ccgaagtact ggatgttgtg
     3421 gcgttgttct tcattttctg gatcaagtgg agacacacag catgagatac agctcatttc
     3481 accatatccg tctttagcca ttgttgttac accttcgtat tggatagaag agtgtttgtg
     3541 gctcatgtgc atacagtagc gacggaagtt gtatggcaat ttgtcagtcc aaagaactgt
     3601 caagtttggt tctggtgagt taccgatgtt gtcaagagtg ttcaagaaac ggtagtccat
     3661 cttagtaaca cggtgacgac cgtcgttacc cataccagcc atagaagttg tgataaaggt
     3721 tgggtcacct gagtacaatt ggtcataagc tttggtacga gcaaatttaa ctgtacgaag
     3781 tttcataacg aaatcatcaa cgaattcttg gatttctgat tcagtaaatg taccacgagc
     3841 aaggtcacgt tctgcaaaga tgtccaatac gattggtaca cgacctagag atgtagcagc
     3901 accgttaatc acacggcaga cagccatgaa agcaatgtta acccattgga ttgcttcttt
     3961 cacgttcatc gctggtttgc gaacatcaac cccgtaaagg tcacccaggc gaacaacttg
     4021 ttgcaatgct tggtattgaa ggtttacttc ttcacgaaga cggattgttt cttcatcgat
     4081 ttctttgatt gcattccagt cgtttacttt ttcttgcatc aagtagtctg caccgtaaag
     4141 agcaagacgt gcgtaaacac cgatgatacg tccgcgtgag tatgcatctg gaagaccagt
     4201 tacagtgtgt gcatgacgag cgcgacgaat atttgaagtg taggcacgga aaataccgtc
     4261 gttaactgtt gttacatatt tagtgaagat ttcgtgaaca gctgggtctg gttcgtatcc
     4321 attttctttt aaagtagttt cagccatacg gataccacct tttggcatga agttcaattt
     4381 gaagagttca tcattttgga taccaaagat aacttcattt tctttgtcga taaatccagc
     4441 agggatatca gcgatagatg ttggacgagt gtccattggg aaacgagttt cttcgtagtg
     4501 tgctttagtt tcttctacaa ttttcttgat gtgaagtgaa cgctctgttg gtcctgcaag
     4561 gaagctttcg tctccatcat aaggtgtgta gttagcttgt acaaagcgtg atacacttgc
     4621 tttttctttc caatctacgc ctttgaagcc ttcccaagct ttgtcaaaaa tatcttgtgc
     4681 ttcaacaact gtcttaacaa ccatattaat gtcctctttt ttctagtaac agtcatctgt
     4741 tacattcata agacaagtat accataaagt aaccgatttc aacaagtgca aaatccctat
     4801 ttttacactt tcttttctaa aacagtctat attttatttc aaactgtatt atatttttga
     4861 aaaaaataaa gtcctttttt ctttttttca gaaaaaaggg tataataaaa gaaaataagc
     4921 agtaacactc aatggaaatc gaaaagcaaa ctaggaagct agccgcaggc tgctcaaaac
     4981 actgttttga ggttgcagat agagctgacg tggtttgaag agattttcga agagtataaa
     5041 aaggtgctag gcatgttgat ttttcctttg ttaaatgatt tgtcaagaaa aatcatccat
     5101 attgacatgg atgccttttt tgctgcagtg gaaatcaggg ataatcctaa actcagagga
     5161 aaacctgtca ttattggaag cgaccctcgg caaacaggtg gacggggagt cgtttctacc
     5221 tgtagttatg aggcaagagc ttttggtgtc cattctgcca tgagttccaa ggaagcttat
     5281 gaacgttgtc cccaggccgt ctttatctca ggaaattatg agaaatacaa agctgtggga
     5341 ctccagattc gagctatttt taagcgctat acagatttga ttgaacccat gagcattgac
     5401 gaagcctatt tggatgtgac agaaaataaa ctcggtatca agtcagcggt caaaattgct
     5461 cgcctcattc aaaaagatat ctggcaagaa ctccatctaa ctgcttctgc cggtatttcc
     5521 tataacaagt tcttagctaa aatggcgagt gattatcaaa aacctcatgg tttgacagtg
     5581 attctacctg aacaggctga ggattttctc aaacaaatga atatttccaa atttcatgga
     5641 gtaggaaaaa agacagtaga acgtcttcat caaatgggcg tttttactgg tgctgattta
     5701 cttgaagttc ctgaggtaac cctaatagac cgttttggta gactaggcta tgatctgtat
     5761 cgaaaggctc gtggcattca caactctcca gtcaaatcca atcgcatccg taaatcaatc
     5821 ggcaaggaga aaacctacgg gaagattctc cgtgccgagg aagatatcaa aaaagagctg
     5881 actcttctat cagaaaaagt cgctctcaat ctacatcaac aagaaaaagc tggaaaaatt
     5941 gtcattttga aaatccgcta cgaggacttt tcaactctta ccaaacgaaa aagtcttgct
     6001 caaaaaacac aagatgctag tcagataagc caaatagccc tgcaactcta tgaagaatta
     6061 agcgagaaag aaagaggtgt ccgcctattg gggattacca tgactggatt ttaaagctca
     6121 atgaaaatca aagagcaaac taggaagcta gccgcaggct gctcaaaaca ctgttttgag
     6181 gttgcagata aagctgacgc ggtttgaaga gattttctaa gagtataaaa ccttgaagag
     6241 ttgccccttc aaggtttttc ttatacaaat aaacggacaa aactgtaaag tagcaaaaca
     6301 ctaccaagca cgatacggta tttaccaaaa agggtgaagt cgtgtttttt cacatagctg
     6361 gtcaagaagc gaatagccac catactgacc gcaaaagcta ctcccatcgc gaccaagagc
     6421 aaaaacaatt gcccaaagct caagagttct cctgctttta caaatttgaa aatctttaag
     6481 gcactagctc caaacataac gggaatccca agatagaagg taaattctgt cacaactgaa
     6541 cgactggttc catttaacaa accaccgaca atcgttgcac ctgaacggct agtccctggt
     6601 aaaagagcaa gaacttggaa gagtccgata tagaaagcgg tcgtataagg aagcttgtcc
     6661 aactctgtta cacttggctc gatagcacgc gctttattgc gcttttccaa atagatgaag
     6721 gcaaccccgt agataatcaa catgagagca actgaaacca tgttatggaa gtgggtatca
     6781 aaccaatcat caaatttaaa gacaccaagt aaaggcaaag tggcaatcaa gaccttcaac
     6841 catagtctcc aagtcttacg aacttcctgt ttgtccttag tcggtttaaa aggattgagc
     6901 ttgttaaaat aaatcaccat aactgctaaa atagcaccaa gctgaatcac gacattaaac
     6961 atggacataa aggcttcatt ttgattttgg tattggataa actcctctgc taaaatcaag
     7021 tgacctgtac tggaaatcgg caaccattcc gtaattcctt caacaatccc gaagaagata
     7081 gattttaaaa tttcaataag atacatatat ttctccttat attatattta acgcagttag
     7141 ctactgccaa agcccaagtg gtatacttgg aataagccac tgtggattag ttcatttcct
     7201 ccaatcgctt gacgatttcc gaaagggtct aaccacagct ttttgtttca attggtaatg
     7261 agtttgataa cgcatagacg ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga
     7321 taaccaagta gacttgaaat actatatctg gaggtactcc catgctttat gtgggcattg
     7381 atgtcgctaa aaataaacac gatgttacag ccttgaatgt tcgaggaaaa ctgttcttaa
     7441 accactcact ttttcaaata ataaagctgg ttttgaactc ttagatctgt cttttcgaca
     7501 gctcaaccaa gactgtctca tcgctcttaa acttctttct gaccccaatc gtgaacaatt
     7561 tcaacacgat aatcggcaag tagacctaaa aatactggct agacatattc atcgtctcaa
     7621 gagaaaacag tctgattgga aagtacaata cactcgttgt cttgatatca tctttcctga
     7681 gttggataaa atcgttggaa agcattcaga atatacctac caactcttga cacgctaccc
     7741 taatcctcag aaaaggattg aggcaggatt tgataagctg atagaaatta agcgattgac
     7801 cgcttctaaa attcaggata tcctctcagt cgcacctcgt tctatcggaa caacatctcc
     7861 tgctcgtgaa ttcgaaatca tcaaacatta caagaggctc attgacaagg cggaaacatg
     7921 tgtcaatgac ttgatggctg agttcaactc ggtcatcacg acggttactg ggattgggaa
     7981 tcgtttaggg gcagtcattt tagccgagat tcgaaatatt catgcctttg atattcctgc
     8041 tcaattacaa gctttcgctg gactagattc ttctatttat cagtcaggtc agattgattt
     8101 agcaggaaga atggtcaaac agggttcccc tcatctgcgg taggtactca tacaagctgc
     8161 caaagcatgc cctcgctttt cacctgcttt taaggcctat cttaagacta agttagaaca
     8221 aggaaaacat tacaatgtag ccatcatcca ccttgcaaaa aaacttatcc gaaccctgtt
     8281 ttatatccta aaaaagagct gccatttgac gaacaaaaag tgatgtaatt tctgaaatta
     8341 acacaggatt acctttgaaa aaatggactt tttcaagagc tttttgccgt gctctaaaat
     8401 catcgccaaa tcatcaaatt gaaataagaa atagtttaga taaaactatt gacttttctt
     8461 atagtttgtc ttttttctat cttccattat atcatacttt ttcagtctat ggtagctctc
     8521 tttaaaaggc accgatactg ccgccacctc cgcctccaga gaagccacca ccagaacttc
     8581 cacttccaga agatacagag taggtgcttg ctgtatttgc gacactagca taatggctca
     8641 tttgtgctgt tgaatgataa aacatactgt gccagccata agctacatag agattgatat
     8701 ctggattttc aacttgaatc tgatgaacct tcatcaaatg actaaccttg tccgcatagc
     8761 caaataaggt tgcatagacc aagagacgat tccaaacaac aatactttcc aattcagcct
     8821 tatccagtcg tgcaatctca cgtaacatat tttcaaaact ggtccagaga tagtagacct
     8881 cagctcccgc ttcatttaga acaccatcac gattatctag tcgaagcttc caataataga
     8941 aaacagacaa aactaaccct agaaaaccaa gtattggcaa agggaggtaa agatagccat
     9001 gaacgtctaa actgtacaag aacaaaccaa atccgataaa taagggcaag atagtcaaga
     9061 cacccatacc cacttgcaaa gccttttcca aaccagttaa aggacgatag taatctggga
     9121 gcccccagaa ggaaactcgt tttctcactc cttcttgcat ctggttcaat acctcttcaa
     9181 aagaagattt gagttgaagc cctcttgctt gaatccgttt ttcatcagaa actttggctc
     9241 tacgataaag actatcagat accttgtaat ccgcaaacaa attggaaaga gtttcttctt
     9301 ttttacctga aaaagctaga tttaggcagt ctttctcaaa gcttgacaaa ccatcttctt
     9361 ttactagcct caaaccaact gcatctcctt ctgaaatgat agagacattc ccacggtcta
     9421 tcacatctag caaggtagct tgaataagtt gatcaaaggt gaattttcca gctcccttga
     9481 ccaagggact cacttcctcc aaggaggtcg agtagactgc ttctgataaa accataggct
     9541 ctaattccat tgggggttca tagagacgat gatttttagc atatttgatt gaaggagcgg
     9601 tctttcttct atagataaaa tagaaacaga tgctcaataa caaggagatg gaaaggatcg
     9661 aagggaagat ccaagtaagt agttgtttac tttgctcttt ttctttaacg atcgaatcct
     9721 ctatcttatt aaactcttct aaacgattcc ctttcaagcc ctgatcccta gcgctagcaa
     9781 aatcagttcg cggccagtag gcatgcaatt caactccacg cttagccgga agattgtcta
     9841 aacgaatagt ataatcaagg ttactctttt caaccgttct ctctctaaaa agtttccctg
     9901 tatggaaaaa gagtttctca gcccccttgt ctccccttac atgaaattca aacttttcaa
     9961 tagactctga actatctgtc ataggttgcc aatttaattc agcgatatca tcataaagga
    10021 aaagtaaatt ttttaagttc cagacgaggt caacttcaac tatgtcgccc tcctgacctg
    10081 gattatagac tctcacagta taaccatccg cttcttctgt tacttcgcta gtcacatctg
    10141 ctagttctgc accgtttttt gcggcctgaa tctttggatg agggtcaatg tcaaacccgc
    10201 taggcatctt accagcacgt ccaagtccca cgatttggcc cttaaagtcc tcctcaaact
    10261 ggtaaactat cttctgtcta aactctgccg tattgtctgc atgaatatac aaatcccctt
    10321 gataagagtt tatcttgaaa tcaatggcaa aaacagagag tggaagaagg caaaacaagc
    10381 ctaacaccag taagaaaaaa gtttttttca tcaactaagc ccccttttta tctttcttat
    10441 cattatagca ttttttcgta agtaaaggct tacttatgtt gaaaaattac gcatttttcg
    10501 ataaaatagg agacagttat tttttaatag atcagaatag gagaaatcat gagaaaaata
    10561 tacttatcta ttttcacaag tctcttgctg atgctaggac ttgtcaatgt tgctcaagcc
    10621 gatgaatatt tacgcatcgg tatggaagca gcatatgctc cctttaactg gacccaggat
    10681 gatgatagca acggagctgt caaaatcgat gggaccaatc agtatgccaa cggatacgat
    10741 gttcaaatcg ccaagaaaat cgctaaggac ttaggtaaag aacctttggt tgttaaaacc
    10801 aagtgggaag gtctagtccc tgcccttact tctggtaaga ttgacatgat tatcgcaggt
    10861 atgagtccaa ctgcagaacg caaacaagaa attgcctttt cgagcagtta ctatactagc
    10921 gaaccagttt tgcttgtcaa aaaagattct gcctacgcaa gtgctaaatc tttggatgac
    10981 tttaacggtg caaaaatcac ttctcaacaa ggggtctacc tttatgactt gattgcacaa
    11041 atcccaggtg ctaaaaaaga aacagccatg ggagacttcg ctcaaatgcg acaagctctt
    11101 gaggctggtg tcattgatgc ttatgtttct gaacgtccag aagcactgac tgctgaagct
    11161 gcgaactcta agttcaagat gattcaagta gaacctggtt tcaaaactgg ggaagaagat
    11221 acagctatcg ctatcgggct tcgtaaaaat gacaatcgta ttagccaaat caatgccagc
    11281 attgaaacca tttcaaaaga tgaccaagtt gccttgatgg atcgtatgat caaggaacaa
    11341 cctgccgaag ctacaacaac tgaagagact agcagtagtt tctttagcca agttgctaaa
    11401 attctttctg aaaactggca acaactcttg cgtggtgctg gtatcactct tttaatctct
    11461 atcgtcggaa ccatcatagg tctcattatt ggacttgcca ttggtgtctt ccgtactgct
    11521 cctctctctg aaaacaaagt catttacggc ctacaaaaac tagtcggctg gggtctcaat
    11581 gtctacattg aaattttccg tggtacgcca atgattgttc aatcgatggt tatctactat
    11641 ggaactgccc aagctttcgg gatcaacctt gaccgtacac tggctgctat cttcatcgtt
    11701 tcaatcaata ccggtgccta catgactgaa atcgtccgtg gtggtatcct agcagttgac
    11761 aagggacaat ttgaagctgc gactgctctt ggtatgaccc ataaccagac catgcgtaag
    11821 attgtcctac ctcaggtagt ccgtaacatc ctacctgcaa ctggtaatga atttgtcatc
    11881 aatatcaaag atacatctgt attgaacgtt atctctgttg tcgaacttta tttctcagga
    11941 aataccgtgg caacacaaac ctatcaatac ttccagacat ttacaatcat cgccgtgatt
    12001 tactttgtcc tcaccttcac cgtaacacgt atcctacgct ttatcgagcg cagaatggac
    12061 atggatacct acactacagg tgctaaccaa atgcaaacgg aggatttgaa ataatgacac
    12121 aagcaatcct tgaaattaaa cacctcaaaa aatcctatgg acaaaacgaa gtgctaaaag
    12181 acatttcact cactgtccac aagggagagg tcatctctat catcggaagc tctggaagcg
    12241 gaaaatcgac cttcctacgc tccattaacc tacttgaaac accaactgat ggacaaatcc
    12301 tttatcatgg acaaaacgtc ctcgaaaaag gctatgacct cacgcaatac cgtgaaaagt
    12361 tggggatggt tttccaatcc tttaacctct ttgaaaatct caatgttctt gaaaacacaa
    12421 tcgtcgctca gacaactgtc ctaaaacgcg aacgcacaga agctgaaaag attgccaaag
    12481 aaaacctgga aaaggtcggc atgggagaac gctactggca agccagacca aaacaactct
    12541 caggtggtca aaaacaacgt gtggccatcg ctcgtgccct ctccatgaat ccggacgcta
    12601 ttctctttga tgaaccaaca tcagctctcg atccagaaat ggttggagaa gtcctcaaaa
    12661 tcatgcagga cctggctcag gaaggcttga ccatgattgt cgtaacccat gaaatggaat
    12721 ttgcccgtga tgtctctcac cgtgttatct ttatggataa gggcgtgatc gctgaagaag
    12781 gtaaaccaga agacctcttc tccaatccta aagaagaccg aacaaaagag ttccttcaac
    12841 gctatctcaa ataaaaagaa aaggctgcat caaccgtgca gtctttttgc tgtcctcaaa
    12901 atgaaaaggc agattctcta tctctactac ttgaaggtca agaatccgcc gttatccaaa
    12961 gattaatctt caaatttttc ataatttttt tcatagaaat caattaggcc tagggctgtt
    13021 tcaaatgaaa tattttttac ttttgcacga ccctgcgcca gagcaatgat agacatttca
    13081 cgcgcattcg tttctttaga gatacggtag cctgtgattt tcttatcacg aacccagcca
    13141 acaactgatt ctactttttc aaagtttgac ttagccatgt ttttctccta ttttcttctt
    13201 tataatattt aattgtatac gtttttacta cttttgtcaa taaaaaaaac atatattcaa
    13261 cgaaaataat tagttcagaa ttttcttact tcctttttaa atccgataac atataggttt
    13321 tgctagcctc tacaccataa atatttgcta ataaaaatac tgtattatta ccctcttaag
    13381 gtgcgaaatt attcaagttc ttaaaaaatg cttctctatt tccgtaagat agcttatttc
    13441 ttcgatttaa gaactgaaga tgatagttct aacctttaga aatccaagcc ttcactagct
    13501 caaaaactcc tatctttctt cctcaataaa tcatctgaga gataggtatt ccttatgtcc
    13561 ttcaaattca tcactccttt ggatattgag gtgctagcct agaagcagac acccgattat
    13621 ctaaaccatc cttaatagag atgacaagac agataagctc agttaattac ttatatatct
    13681 ttttaatatg gtatatttgt caacaaaaag aaatcaaatc ataccttata ctcaatgaaa
    13741 atcaaagagc aaactaggaa gctagccgca agttgctcaa aacactgttt tgaggttgca
    13801 gatagagcta acgtggtttg aagagatttt cgaagagtat taaaaacagt gtgactatgc
    13861 ttgtcaatag ataggaaatc aaaatgaagg atggaaatct gagccaaaca tcataagtgc
    13921 tataatgaac agaagtaaga attgcacgat aagttttcta aaaccatagg aatcgtcccc
    13981 tttcttcatc ttcattatag cacatataca tcagttgtac aaataatatg atattttttt
    14041 attagtcctc agacaagcat attataaagc gtttcattac catttaagtt aatataagct
    14101 ggatcaaaac cttccattct acgaatcaaa cctgcataat catgcttatc tgctaaagcg
    14161 atcccaatta atactgggcc tgttcccttg ctagctcgtt tgatatactc aaaacgtgtg
    14221 atatcatcat ttggccccag gatatcattt acaaactcac gcaaagctcc tggacgttgt
    14281 gggaaattga ccacaaagta atgtttgata ccatcataaa tcaaggcacg ctcttccatt
    14341 tctggcatac ggttgatatc attatttcct ccagaaatga tacaacaaat ggttttcccc
    14401 ttaatatatt cagctaaaac ctctaaagag gcgatactag ccgctccagc aggttctgcg
    14461 actatccctt gcttagagta aaggtcaatc aaggtttcag aaatcaatcc ctcatcgaca
    14521 cctaccaaag ttttaatatg ttgacgagtt gcttcatagg tcaactgacc taccttttgc
    14581 acagcaatcc catcagcaaa tttatcaatt tccttgagtt ttactggacc tccagcctca
    14641 aaggcagctt tcatggaacg cgctccattc gcctctactc cgataacctc aatctctgga
    14701 cttgtttcct tgatataggt agaaaccccg gcaatgagac cgccaccacc aacaggaacc
    14761 aagacagcat caaaatcaat cgattctttt cgagcttctt ctaaaatctc ataagcaact
    14821 gttccttgac ctgcttgaac atgagcatca tcaaaaggat caataaaggt acgattttca
    14881 gagactgtaa attcttgagc tgctttggct gaggcatcaa aggtatctcc aactagttta
    14941 atagttacaa aatccccacc aaaaaagcga acctgaccaa tcttttgttg tggcgtagta
    15001 atgggcataa agatagtagc aggaattttc atttcattac aagtataggc tactccctgc
    15061 gcatgatttc ccgcagaagc gcagactacc ccacgttcac gttcttcctt gctgagctgg
    15121 gaaatggcat aataggcacc acgaatttta aaggagcgaa cacgctgggc attttctttt
    15181 ttcaaataaa tcttagcacc atacttctcc gataaataat gatcgtaatc cagtggagta
    15241 ttcacaacca caccgttcaa gaccttgtga gccttgatta tatcttttga acttaacata
    15301 taaaacctct ttttctataa aaaacagtca ctaatgactg ttttttagtt attcatctcc
    15361 gaaaacttca gtaacacttt catggtattt atgagccata cgaatcgaaa actctttagg
    15421 aagttcataa cgatttgtgg aaatccaatc atataaccat tctaccaaac tttcttcact
    15481 atcattacga tggaagataa aatagtttaa aatttcttta tattctacat cattcaaatc
    15541 caacgtgtct acaaattgac tacgaggaac aaaattagaa tctaattttc ttagttgatc
    15601 tgtcaattct cccaattgta aatccaactg aaaaaatagt ttttgcagtt gcctatcagt
    15661 ttcatcacat cctgtcttga tagaaaacaa attggtaata ttcatatgat ttcaacccct
    15721 aaataagtac atctaatatc ccacgaatag ctgaagctaa agttttcgca gtccagtcat
    15781 ttaaacccga ttctttcaat ccagatgcaa taatttgctc tatttgatat aaaccgccat
    15841 ctatcgtctc atttattctg cgaagaggac cttcaatata ggataaagct tctccgaatc
    15901 taacagctga tttaggtcct aatgatttac caactatatt tgttaatgtt ttttatttct
    15961 caaaatccat ttcgctatat aacgagcaga tttagtcgca ccagctctct caaacggaaa
    16021 atgaatttca agaccttctt ctctagctat ttgtgccaat ttgaagaatt gttcaaaggt
    16081 catatgcaac ctaccatctt caaaattagc atcatcataa atgttaatta cagtattttc
    16141 atcatacgac caatctgctt tattttggtc tgctagcact attaccgacg gtgtaattac
    16201 attatacaac tagaaccaat aataacgatg caatttttct cataatcttt ttcataaaat
    16261 catctccagc gctatatatt tctaattagt tatagatttt gaatgcatca tcgtcgtttt
    16321 taccaacgaa tggcattgct ttacgcaatt ctgcaccaac tttttcaatt tcaaggttag
    16381 ctgcttgttc acggtaagca gtcaattttg gacgtccagc tttatagtca tttacaaagt
    16441 catttgcaaa tttaccattt tggatgtctg ccaagacagc cttcatattt tctttaactt
    16501 gttcagtgat tacacgtgga cctgatacat agtcaccgta ttcagcagtg tttgaaatag
    16561 attgacgcat tttcttgaat ccaccttcgt agatcaagtc aacgatcaat ttcatttcgt
    16621 gaagaacttc aaagtaagcc aattctggag cgtaacctgc ttctgtcaag acttcgaaac
    16681 ctgcttcgat aagggcagtc aaaccaccac aaagtacagc ttgttcacca aacaaatctt
    16741 cttcagtttc ttctttgtaa gttgtttcaa gaagacctac acgagccgct ccaacacctt
    16801 tacaccagtc catagcaatg tttttagcat ttcctgttgc atcttggtat actgcataaa
    16861 gagctggaac accaaatcct tcttcgtaag tacgacgtac caagtgtcct ggtcctttag
    16921 gagcacacat gaagacatct acatccgcag gaactttgat aaattcaaag tggatgttga
    16981 aaccatgggc aaatccaact gcgtttccag cttccaagtt tggagcgatt tctgcttcgt
    17041 acaattcttg ttgaatttcg tctggcgcca agatcatgat aacatcagcc aacttagtag
    17101 cttctgttac tgtgtaagta tcaaatccat cttcttttgc tttatcaaaa gatttacctg
    17161 gacgtacacc gataataacg tcacgacctg aatcacgcaa gttttgagca tgcgcatgcc
    17221 cttgtgaacc ataaccgata acggcgattt ttttaccgtc aagtgctgct actttaacat
    17281 ctttttcata ttccatttga actgtcatag cttttctctc ttttctatta tttattgcct
    17341 tttaagctgg tttaacaaat ttaagttgga tttttaatcg cgggtaaatc cagttgcacc
    17401 cgttcgagca atattgcgaa taccgtatgg gcgaatgact cgcaataggg cttcgctctt
    17461 ttctgcattt cccgtcatct gaatggtaat cgagcttggc gctacgtcta ccactgttgc
    17521 acggaaaggt tgaataatcg ctaaaatctc agctctcttc tcagctggcg ctgacatctt
    17581 aaccaaaatc acctcgcgct ccaaatgagg cttgtctgta atatctcgaa tgcgaatcac
    17641 atcaatctga cgattgagct gtttgatgat ttgctccact tcatcatgag aagcaacatc
    17701 aataataata gtgatacgcg atacattcgg atcttctgtt gctccaacag agatgctttc
    17761 aatattaacc tgacgacgag ataggacacc tgtaaagcga ttgaggactc ctgaacgatt
    17821 ttgtagtttt gctgttaaca ttctacgcat ggaacttcac ccccaacatc tcatgattac
    17881 tcttaccagc cggtaccatt ggtaacacct gttccttacg agaaatatct acctcaatta
    17941 gcataggaac atcctcagtg atgacttcaa ggtcttgagc caaggtctca ggattgtcaa
    18001 acttatagtt tttaatacca taagcctgcg ccatcaattg gaaatcagga agggtatcaa
    18061 agaccgactc tgatgttctg ccttcataga aggattcctg ccactggcga accattccaa
    18121 gtgaatgatt gttcagcata accaccttga ttggcacctt gtaaatattc aaaatagcca
    18181 actcctggtt ggtcatttgg aaaccaccat ccccaacaaa caagactact tccttatctg
    18241 ggttagcaat tttagcaccg attgctgctg gaattccaaa gcccattgtt cccaaaccac
    18301 ctgaagtcac taactgacgc tcattttggt agggataata ctgagctgtc cacatttggt
    18361 gttgaccaac gtctgttacc acaatggcat ctccattcgt caattcacca attcgttcaa
    18421 taactgcttg cggttgaacc acacgctctt tcttgtcata agaacgaaca cgattcttgt
    18481 ctttagtgac tttctcaatc cacttttcag tattgttgtg aactgttggt tctgctagca
    18541 acatttgcaa ggccttctta gcatctccaa ctacaggaat gtctgcactg ataatcttgc
    18601 caatctcagc tgggtcaata tcaatgtggg caaccttagc attcttagcg aaagtcttag
    18661 gattccccgt caaacggtca tcgaaacgag aaccaatact aatcataaag tccgcttccg
    18721 tcatggcaat atttgctgcg aatgacccgt gcatgcctcc cattccaaga aagagtgggt
    18781 gactcgttgc aatcgttcct tgtcccaaaa gactggttac cactggaatt tgatagcgtt
    18841 ctgcaaattc atttagttcc gtagcagcct cagcataact aattccacca ccagctaaca
    18901 agactggctt tttagccttg gacaattgct tcaagatttt cttgatttgc atatcattcg
    18961 gctcaagagt cggctgataa cttggtaaat tcacttctgg tgaataaatg aagtctgttt
    19021 ctaaagcaga tatgtctttt ggtaggtcaa ttacaactgg ccctggacgg cctgtagttg
    19081 cgatatggac agcttccgtg atgatacgcg gaatatcagc tgtctcacga acttggtaat
    19141 tgtacttagt gattggcatg gtaattccca cgatgtctgc ctcctgaaag gcatccttcc
    19201 caatccctgc tcgcgccacc tgacctgtaa agaccaaaag gggaacgcta tcgctcatgg
    19261 catccgcaat ccctgtaatg gcatttgttg ctcctggtcc actagtgacg acggcaacac
    19321 ccaactttcc agttgatttg gcataacctt cagcttcatg caaacaacct tgctcatggc
    19381 gccctagaat gtggcgaatg cctttaaaat tatatatcgc atcataaaaa ggcaaaaccg
    19441 caccaccagg ataaccaaag atggtatcaa ctcctaaatc acgaagtgtt tccaaaacta
    19501 ggtccgaccc cgtcttagga gattctaaac tgattttctc cattattccc ctttctttcc
    19561 tcttaaaaat aacttgttac tatcatacca ttttttcaaa atttttcaag ataaaagaag
    19621 aaattttctg aattttctat tttaacgttt atttatgaat gttatttttg tttttattaa
    19681 aaagataccg atttcattta ctaaaaaaga aaaaagaact gatttctcag tccttcatta
    19741 atcttattcc acactaaata ggtatgggta aacaggttgt tgaccttggt gaatctcgac
    19801 ttcaacgtct tcgaattctt ctacgatttc ttgagcgatt tcattggcaa gttcttcgct
    19861 tccgtcttca ccgacataga aggttacgat ttcactgtct tcatccaaca tatgtttcaa
    19921 ggtttcagtc aatgtttggt gcatatcagg gtttgacaca agaatttttc catccaccat
    19981 acctagatta tcgttttcat ggatttctaa gccatcgatc gttgtatcac gcacggctgt
    20041 tgtgacgctt ccgctaacaa catcgctaag agcagctgtc atacgctctt ggttttcttc
    20101 aatggacttg cttggatcaa aggcaagaag acttgtcata ccttgaggaa gagtgcgagc
    20161 ctctaccact actgctggtt gctccaaaac ttctgccgca gattgagctg ccatgaagat
    20221 gttcttgttg tttggcaaga agatgatgtt acgggcattg acctgttcaa cagccttgat
    20281 aaagtcttct gttgaagggt tcatggtttg accgccttcg ataacataat ccacgccttg
    20341 agaacagaag atatctgcta gacctttacc agccaccaca gcaatcaaag catactcttt
    20401 ttcttcagcc gacttgataa cttgagtagc ttctttctca acctgtgctt cgtgttggtt
    20461 acgcatattg tcaactttta ccttgaccaa gctaccatat ttgagacctt cttgcataac
    20521 aagtcctgga tcttctgtat gaacatggac tttgacaatt tcatcatcgt taacaacgag
    20581 gagagaatcc ccaagctcat ccaagtagtt acggaattca tcgtagtcaa aatctttagc
    20641 ataggttgga ccttgcttaa gagctaccat gatttcagta cagtaaccaa acgtgatgtc
    20701 ctcagtcgct acgtgaccag ctacagactt atgatgctct acattgatca tctcactcat
    20761 gttggcagga gtcgctacaa agtcctcaga tgcaatatat tcgccagtaa gggctgaaag
    20821 gaaaccttcg tagatgaaga ccaatccttg accacctgag tccacaacgc caacttcttt
    20881 caatactgga agcatgtctg gtgttttagc tagagctgtt ttagcacctt ccaaggctgc
    20941 gcgcatgact tcaacagcgt catctgtttg ctcagctttt ttcttagcac cgatagcagc
    21001 tccacgagaa actgttaaaa tcgttccttc aacaggtttc atcactgcct tataggcaac
    21061 ttccacacct gattggaagg ccagagccaa gtcttgacct gttaactcgt ctttatcctt
    21121 gatagcttgg gaaaatccac ggaaaagctg agacgtaatc actcctgagt tcccacgcgc
    21181 acccatcaaa agccctttgg caagaatgct cgctacttct ccaactgtag aagctggctt
    21241 gtctgcaact tctttagcac cattttcaat ggtcattccc atatttgtcc cagtatctcc
    21301 atctggaact ggaaagacgt ttaatgaatt gacatattca gcttgcttat tcaagcgagt
    21361 tgatgcagcc tgcaccattt cttgaaataa gctagtagta atttttgaca cggttattct
    21421 cctacaactt tgatattttg aatgtagaca tttacagtct gagcagtaat tccaagctgg
    21481 ttttccaagc taaaggcaac acgctcttga atgttttttg acacttcact aatctttgtt
    21541 ccgtagctta acacggtata tacatcaact gcaatactgc catcttcggc tgcctttacg
    21601 acgacacctt tagaataatt ttccttacct agcagggctt ggaaattatc tttgagggca
    21661 tttttactag ccataccgac cacaccaaaa atctcagttg ctgctccacc tacgacggtt
    21721 gcaatcactt catctgttag ttcgatttga ccatcttttg tattaatttt tacagtcatc
    21781 ctttttacct caactagttg atactctatt ttatcatatt tcagcccaag tgtaaaagca
    21841 gaatgatgta tcagcggata tttactctat ttttcaaacg a
//
LOCUS       DAVKAU010000027        21605 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVKAU010000027 DAVKAU010000000
VERSION     DAVKAU010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21605
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.027"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            112..765
                     /locus_tag="VWX48_001255"
     CDS             112..765
                     /locus_tag="VWX48_001255"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU9171881.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            775..1239
                     /locus_tag="VWX48_001256"
     CDS             775..1239
                     /locus_tag="VWX48_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9171882.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTADLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1252..2520
                     /locus_tag="VWX48_001257"
     CDS             1252..2520
                     /locus_tag="VWX48_001257"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU9171883.1"
                     /translation="MLLIKNGHVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2534..2794
                     /locus_tag="VWX48_001258"
     CDS             2534..2794
                     /locus_tag="VWX48_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171884.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2805..4166
                     /gene="pdrM"
                     /locus_tag="VWX48_001259"
     CDS             2805..4166
                     /gene="pdrM"
                     /locus_tag="VWX48_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU9171885.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4320..5288
                     /locus_tag="VWX48_001260"
     CDS             4320..5288
                     /locus_tag="VWX48_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU9171886.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDFNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAIDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5304..6296
                     /locus_tag="VWX48_001261"
     CDS             5304..6296
                     /locus_tag="VWX48_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU9171887.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6515..7558
                     /locus_tag="VWX48_001262"
     CDS             6515..7558
                     /locus_tag="VWX48_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU9171888.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMNLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7622..9307
                     /gene="lpdA"
                     /locus_tag="VWX48_001263"
     CDS             7622..9307
                     /gene="lpdA"
                     /locus_tag="VWX48_001263"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU9171889.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGSASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDNIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9371..10360
                     /locus_tag="VWX48_001264"
     CDS             9371..10360
                     /locus_tag="VWX48_001264"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU9171890.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10425..11495)
                     /gene="xerS"
                     /locus_tag="VWX48_001265"
     CDS             complement(10425..11495)
                     /gene="xerS"
                     /locus_tag="VWX48_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU9171891.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLKSGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12079..13629)
                     /locus_tag="VWX48_001266"
     CDS             complement(12079..13629)
                     /locus_tag="VWX48_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU9171892.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGSGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13645..14424)
                     /locus_tag="VWX48_001267"
     CDS             complement(13645..14424)
                     /locus_tag="VWX48_001267"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU9171893.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14411..15262)
                     /gene="ylqF"
                     /locus_tag="VWX48_001268"
     CDS             complement(14411..15262)
                     /gene="ylqF"
                     /locus_tag="VWX48_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU9171894.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15481..15657)
                     /locus_tag="VWX48_001269"
     CDS             complement(15481..15657)
                     /locus_tag="VWX48_001269"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9171895.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(15709..21570)
                     /locus_tag="VWX48_001270"
     CDS             complement(15709..21570)
                     /locus_tag="VWX48_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9171896.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELISGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTKLINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSEAVVTDKG
                     EPAVQPELPEAVVSDKGVPEVQPALSEAVVTDKGETEVQPESSDTVVSDKGEPKQVAP
                     LPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAEN
                     PVQPAEESTTNSEKVSPDTSSENTGEVSNKPSDSKPPVEESNQPENSGNTTSENGQTE
                     PEPSNGNSTENVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYS
                     LSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKV
                     EKLQQEIESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANE
                     VELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFESLRGATIEKLSLKNVSISG
                     KDDIGSLANEAQNNTKIKQVHVDGVLAGERGIGGLLAKADQSSITESSFKGRIVNTYE
                     TTASYNIGGLVGHLTGSKASLTKSKATVVISSNTNSSDQTVGGIAGLVDKDAHIQNSY
                     SEGDINNSQRFGKVAGIAGNLWDRESNSENHAGRLTNVLSDVNVTNGNAISGYHYNGM
                     KITDAFSNKANKVFNVTLEKDEVVSKESFEERGTMLDASQIASKKAEINLLTPPIVKP
                     LSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKEL
                     LSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFAKLAEYSLGDTGL
                     LYTPNQFLYDQDSIINQVLPELQQVAYDSEAIRKTLGISPEVKQTELYMEDQFTKTKQ
                     DLANSLKKLLSADAGLAGDNPVTRGYLVDKIKNNKEALLLGLTYLERWYNFSYGQVNV
                     KNLVMYHLDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFST
                     LENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSD
                     SWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLNSFVEKSAHET
                     AERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTDHTEGKATEVANFDNPNPAMK
                     HFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYG
                     RRSGLGPEFFAKGLLQAPDQPSDATITINSILKHKTSDSTEGQRLQVLDPTTRFNDAA
                     DLQNYVHNMFDVVYMLEYLEGQSIVKQLDAYQKMTALRKIENKYVKDPADGNDVYATN
                     VVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSSEKG
                     TPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELV
                     LKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKRWPSYGTKTINNVDELQK
                     LMDEAVLQDATGTRWSNYNPEIDSAVHKLKRAIFKAYLAQTNDFRSSIFENKK"
BASE COUNT         6204 a         4212 c         4397 g         6792 t
ORIGIN      
        1 gtattcaaat cgtatatagt cgatttatta aatctttaga taaattgtaa aaagtggttt
       61 ccatagccac tttttgctat aatagaggca gtaaaaatga aggagtcagc tatggaacac
      121 tcgtcttggc atgctttgat taaggcgcaa ttacctgagg gttatttcgg gaaaatcaat
      181 cagtttatgg agcaggtcta ttctcagggg attatttatc cacccaagga aaaggttttt
      241 caggctctct tgacaacact gcttgaagaa gttaaggtgg taattctagg gcaagacccc
      301 tatcacggac caggtcaagc gcagggcttg agtttttctg tacctgactc tatcccagct
      361 ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg atatcggagt taagaaatct
      421 catgatttga cagcttgggc tgagcaagga gtcttgcttc ttaatgcttg tttgactgtt
      481 cctgctggac aggccaatgg tcatgctggt caaatctggg agccttttac tgatgctgtg
      541 attcaggtgg tcaatcatct agatagacca gtcgtttttg tactctgggg agcttatgca
      601 cgtaagaaga aggccttagt taccaatcct catcacttga ttatcgaatc agcccatcca
      661 agtcctttgt cggtttatag aggattttgg ggttccaagc ccttttccaa agccaatgca
      721 ttcttaaaag agacaggaca agagccaatc gattggctta gataaggaga aaatatgcct
      781 cagttagcga cgatttgcta cattgataat gggaaagaac tgctcatgct ccatcgtaat
      841 aagaaaccca atgatgtcca tgaagggaaa tggattggtg tgggtggtaa gctagagaga
      901 ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg aagaaacagg gctcaaagcc
      961 aagccagttc taaaaggtgt catcactttt cctgaattta cagcagattt agactggtac
     1021 acctatgttt ttaaggtgac ggagtttgag ggcgacttga ttgactgcaa tgaggggacg
     1081 ctagaatggg ttccctatga cgaggttttg agcaagccga cttgggaagg tgaccacacc
     1141 tttgttgagt ggcttttaga ggataaaccc ttcttttcag ccaagtttgt ttatgatggg
     1201 gataaattgt tggataccca agttgatttc tatgaataaa ggagaaagca gatgctacta
     1261 atcaaaaatg gtcatgtaat ggatcccaag tctggtttgg atcaagtttg tgatgtctta
     1321 gttcaagatg ggaaaattat caaaattgcg cctgagatca cggaagaagg agcagaaacg
     1381 attgatgcta ctggtcttgt ggttgctcct ggtttggtcg atattcatgt gcatttccgt
     1441 gaacctggtc aaacacataa agaagacatt catactggtg ccctagcagc cgctgcaggt
     1501 ggttttacta ctgtcgtcat gatggctaat accagtccaa ccatttcaga cgtggagact
     1561 ttgcaagcag ttctccagtc agctgccaaa gagaagatta atgtcaagac agttgcgacc
     1621 attactaaaa actttaatgg taaaaacttg actgacttta aggcgctctt agaagctggt
     1681 gcggttggtt tctctgatga cggtattccg cttgagagca gtaagattgt caaggaagcc
     1741 atggaggaag ccaaaaaact caataccttt atcagccttc atgaggaaga tccaggtttg
     1801 aacggtgttc ttggctttaa tgaaaatatt gctagagaac atttccatat ctgtggtgct
     1861 actggggtgg ctgagtacgc tatgatggcg cgtgatgtca tgattgccta tgcaactaaa
     1921 gcccatgttc acatccagca tttgtctaag gaagaaagtg ttaaagtagt ggagtttgct
     1981 caggggttag gtgcagaagt cacagcagaa gtagcaccac agcatttctc taagacagaa
     2041 gcacttcttt taacacaagg tagcaatgct aagatgaatc caccgcttcg tttggaatca
     2101 gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca tcacagttat tgcgactgac
     2161 cacgcgcctc atcatgtaga tgaaaaaaat gttgaagata ttaccaaagc gccatctggt
     2221 atgactggct tagaaacatc cctgtctctc ggcttgacct atttggtaga agctggtgag
     2281 ttgagcttga tggaattact tgaaaaaatg acatacaacc cagccaagct ttacaacttt
     2341 aaagcaggtt acttggctga gaatggtcca gcagatatca ctatttttga tgccaaggct
     2401 gaccgccttg tggactccca ttttgcttcc aaagcagcta attcaccatt catcggtgaa
     2461 accttaaaag ggcaggttaa atataccatc tgtaagggac aaatcgtcta tcaagcttga
     2521 taggagttag aatatgaatt attttcgaaa acgtagggag agacaagcga aatctaatag
     2581 tggaatttac tgtcccgcag ctaatcgttc caaaattcaa tatgaaacta aagaaaaagc
     2641 tgaccatgcg gttcaatatg ataacggagg tttagttaga agctattatt gtcgtacatg
     2701 tgcgtgttgg catactactt caaaatctaa taaacctccg ctaagtttga aaaactatgg
     2761 tctgaaactc tttggtttag ataaatcaga atagaaagag aagtatgtat aagacaaagt
     2821 gtttacgaga gaagttagta ttatttttaa aaattttctt cccaatcctg atctaccaat
     2881 ttgccaatta ttctgcctct tttgttgata ctgcaatgac aggtcaatac aacactatgg
     2941 acttggctgg tgtatctatg gcaaccagta tctggaatcc tttctttaca tttctaacag
     3001 ggattgtgtc agccttggtg cctatcattg gtcaccatct tggtcgaggc aaaaaggaag
     3061 aagttgcgtc tgatttttac caatttattt atttggcctt gggcctatct gtggtcttgc
     3121 tggggatggt acttttcttg gcaccaacaa tcttgaatca tattgggtta gaagcagcag
     3181 tagcggcagt agcggttcgc tatctttggt ttttatctat cgggattatc cccttgttgc
     3241 tctttagcgt cattcgttcc ttgctggatt cgctgggctt gaccaaactg tccatgtacc
     3301 tcatgctttt gttactccct ctcaatagcg gatttaacta tctcttgatt tacggtgcct
     3361 ttggtgttcc agaactggga ggggctggtg ctggtttagg aacatccttg gcctactggg
     3421 tcttgcttgg gatttctgtt ctggttttat ttaaacagga gaagctcaaa gccttacacc
     3481 ttgagaaacg aattccactt aatatggata acattaagga aggagttcgt ttaggtctgc
     3541 ctattggggg aactgtcttc gcggaagtgg ctatcttttc agtggttggc ttgattatgg
     3601 ctaagttttc gtccttgatt atagctagtc accagtcagc tatgaacttt tcaagtctta
     3661 tgtacgcctt tcctatgagt atctcatcgg ctatggctat tgtcgtttcc tatgaagtgg
     3721 gagccaagcg atttgatgat gcgaaaacct atattggtct aggaagatgg actgctctca
     3781 tttttgcggc cttcacccta accttccttt acatttttag gggaaatgtg gccagtcttt
     3841 atggtaacga cccaaaattt atcgatttga cagcgcgttt tttaacttat agtcttttct
     3901 tccagttagc agataccttt gcggcaccgc ttcagggaat tttgcggggg tataaggata
     3961 cagttattcc tttttacctt ggtttgcttg gttattgggg cgtagcaatc cctgtggcta
     4021 cgctatttga ttccctaaca gattttggag cttattctta ctggatcggc ttgattatta
     4081 gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac tgtgattatg aagagatttg
     4141 aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa aatatccttg acaagaaaat
     4201 cccttgtttt cacggggttt tcttttttat tttgtgaaat ttcttttaga aaaactttga
     4261 cagtatttgc caaaagcggt aaaatagtaa ggtaagaaga aagttagaaa ggcaagaaga
     4321 tgtcaacttt agataaaaat cttttgctag aaatgttccg taagatggaa gaaatccgtc
     4381 gcatggactt aaaaattgca caattagtaa agaaagggaa agtgccagga atgacgcact
     4441 tttctgttgg tgaagaggca gctaacgtgg gggctatgtt agctctcaat ccagatgatc
     4501 tgattacctc aaaccaccgt ggacacgggc aagctattgc taaagggatt gacttcaacg
     4561 gaatgatggc tgaaatcctt ggtaaataca ctggaacctg taaagggaaa ggtggatcta
     4621 tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa tggtatcgta ggtggtggta
     4681 tggggatcgc tgtcggtgca gccctcagtc agcaaatgca aaataccggt aaaatcgttg
     4741 tctgcttctt tggagatggt gcgaccaatg aaggtgtttt ccacgaagca gtgaacatgg
     4801 cttctatctg gaacctgcca gtcattttct attgcattaa caacggttac ggtatctctg
     4861 cggatatcaa gaaaatgacc aatatagaac atatccatca acgtagcgcc gcttatggaa
     4921 ttcctggaat gttcatcgaa gacggtaaca atgtcatcga tgtctatgaa ggatttcaga
     4981 aagctataga ccatgttcgc agtggcaatg gtccagtctt gattgaaagt gtaacttatc
     5041 gctggctcgg tcactcatca tctgaccctg gtaaatatcg tacgcgtgaa gaagtggaat
     5101 tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta ccttattgaa aataacattg
     5161 caagtgccga agaattggaa gaaatccaag cgcaagtaaa ggaagcagta gaagcttctg
     5221 ttaaatttgc agaggaaagc ccattcccac cgcttgaatc agcctttgaa gatatttacg
     5281 cagactaagg agaaagagat aaaatggaaa caaaaacaat gtccttccgt gacaccatta
     5341 tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt gttcttgatg ggagaagacg
     5401 tcggtgtctt cggaggagac ttcggtactt ctgttggaat gcttgaagaa tttggtccag
     5461 aacgtgtccg tgactgtccg atttctgaag ctgccatctc tggagctgca gcaggagcag
     5521 ccatgacagg acttcgtcca atcgtcgata tgaccttcat ggacttctct gttattgcca
     5581 tggacaatat cgtcaaccaa gctgctaaaa cacgttacat gtttggtggt aaaggtcagg
     5641 ttccaatgac tgttcgttgt gcagctggta acggagttgg ctctgccgcc cagcactcac
     5701 aatctctaga gtcttggttt actcacattc caggacttaa ggttgtggca cctggaacac
     5761 ctgcggacat gaaaggcctg cttaagtctt ctatccgtga taacaaccca gttattatac
     5821 ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc agttgatcca gactacacaa
     5881 ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga tgtaacagtt gtcacttatg
     5941 gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt agctgaagaa ggaatttcag
     6001 ttgaaattgt tgacccacgt acccttgttc cgcttgataa ggatatcatc ataaactcag
     6061 tgaagaagac tggtaaggtt gttctggtca acgatgccca caaaacaagt ggctatatcg
     6121 gtgaaatttc agctattatt tcagaatcag aagcatttga ctatctagat gcaccaatcc
     6181 gccgttgtgc aggagaagat gtgccgatgc cttatgcaca aaacctagaa aatgcaatga
     6241 ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac ttataacaaa gaatagagtt
     6301 acataagata agttatgtaa ataaaacaaa gctgacgaga aactttgtat cttttaggtg
     6361 cagagctctt cgtccttaat atcttagatt agagcacggg ctaaaagctt ggaaaaaaag
     6421 ataaatctcc ttggcttcat cgaagccatc gtcgatttcc tatttttcag tcgcttttga
     6481 cgccctttgt atcataaata gaattggaga ggtcatggct gatgacaagc taagagcgac
     6541 tcctgcagct agaaagttag cggatgattt agggataaac ctctacgacg tttctggctc
     6601 aggtgcaaac ggtcgtgtcc acaaagaaga cgtggaaact tataaagaca caaacgtggt
     6661 tcgcatttcg ccacttgcaa aacgaattgc cctcgaacat aacattgctt ggcaggaaat
     6721 ccaaggaacc ggtcatcgtg gtaaaatcat gaagaaggat gttttggccc tgcttcctga
     6781 aaatatcgaa aacgatagca tcaaatctcc tgctcagatt gaaaaagtgg aagaagttcc
     6841 tgataacgta acaccatatg gtgaaatcga gcgtattcca atgacaccaa tgcgtaaggt
     6901 tattgcccaa cgcatggttg aatcttactt gactgcgcca accttcaccc tcaactatga
     6961 agttgatatg actgaaatgt tggctcttcg taagaaggtt cttgagccaa tcatggaagc
     7021 aactgggaag aagactactg taacagacct tctttcgctt gcagttgtta agactcttat
     7081 gaaacaccca tacatcaacg cttcattgac agaagatggc aagactatta tcactcacaa
     7141 ctatgtcaat cttgccatgg cagttgggat ggataatgga ttgatgacac ctgttgttta
     7201 caatgctgag aagatgagtc tttcagaact ggttgtagcc tttaaggatg ttattggccg
     7261 taccttggat ggtaaattgg ctccaagtga gttacaaaat tcaacattca caatcagtaa
     7321 tttgggaatg tttggtgttc agtcctttgg tccgattatt aaccaaccca actcagctat
     7381 ccttggtgtc agttcgacaa tcgagaagcc agttgtcgtc aatggtgaaa ttgtgattcg
     7441 cccaatcatg aatttaggat taaccattga ccaccgtgtc gtagatggta tggctggtgc
     7501 taagtttatg aaggacttga aagagttgat tgaaacgcca atctcaatgt tgatttaaga
     7561 gcaagagtat tcatttttaa gatatagata aaggaaggaa gacatggcct tagaagtaat
     7621 tatgccaaaa gccggcgtgg atatgacaga aggacaaatc gtccaatgga ataaaaaagt
     7681 cggagaattt gtaaaagaag gagaaatcct tttggaaatc atgactgata aagtaagcat
     7741 ggaattggaa gccgaagaag atgggtactt gattgccatt ctcaaaggag atggtgaaac
     7801 tgtccctgta acggaagtta tcggttacct tggtgaagaa agggaaaaca tcccaacagc
     7861 tggatcagca tcgccagaag ctagccctgt ccctgtagca agtacctcaa acgatgatgg
     7921 taagagcgat gatgcttttg atatcgttgt gattggtgga ggtcctgctg gttatgttgc
     7981 agccattaaa gctgcccaac tcggcggtaa ggttgccctt gttgagaaat ctgaacttgg
     8041 tggaacctgc ttaaaccgtg gatgtattcc aaccaagacc taccttcata acgctgaaat
     8101 tattgaaaat atcggtcatg ctgcaaatcg tggtatcgtg attgaaaatc ctaacttcac
     8161 tgttgatatg gaaaaacttt tagaaactaa atctaaagtt gttaatactc ttgttggtgg
     8221 tgttgcagga cttcttcgta gctacggagt tactgttcat aaaggaattg gtacaatcac
     8281 taaagacaag aacgtcttgg taaatggttc tgaattgctt gaaaccaaga agatcattct
     8341 tgctggtggt tcaaaagtca gcaagatcaa cgtccctggt atggaatctc cacttgtcat
     8401 gactagtgat gacattcttg aaatgaacga agtgccagaa agccttgtta tcatcggtgg
     8461 tggagttgtc ggtatcgaac tcggtcaggc cttcatgaca tttggttcaa aagtgactgt
     8521 tatcgaaatg atggaccgta tagttccagc tatggatgcg gaagtttcta agaaccttcg
     8581 cttgatcctt gagcgtaaag gaatgaccat cttgactggt actaaactgc aagaaatcat
     8641 tgaggaaaat ggtcaacttc gtatcaaggt tgaaggaaaa gacaatatca tcgcaagcaa
     8701 agctcttctt tcaattggtc gtatgccaga ccttgaaggt attggagagg ttgagtttga
     8761 attggatcgt ggttgtatca aggtcaatga atacatggaa acttcagttc caggcattta
     8821 tgcaccaggt gacatcaacg gtactaagat gttggctcac gcagctttcc gcatgggtga
     8881 agtttccgct gaaaatgccc ttaaaggaaa tcatgcagtt gccaaattga atttgactcc
     8941 tgcagccatc tacactctcc ctgaagtagc agcagtaggt ttgacagaag aacaagcccg
     9001 tgagaaatac gatgttgcca tcggtaagtt taactttgct gctaacggtc gtgctattgc
     9061 atctgacgca gctcaaggtt tcgtaaaagt tatcgctgat aagaaatacg gagaaatcct
     9121 tggtgtacac attattggtc ctgcagccgc agaattaata aacgaagcat caagcatcat
     9181 cgaaatggaa atcactgttg aggaaatgct gaagaccatc cacggacacc caacttactc
     9241 tgaagtgatg tacgaagcgt ttgcagatgt tctaggaatg gccatccatt cacctaagaa
     9301 aaaataaaac gaagatagat tagactggaa ggttatttcc agtctctatc atataaagta
     9361 aagggatatc atgaaataca ttatcaatca ttcaaatgac actgctttta atattgcctt
     9421 ggaagaatac gcctttaaac accttttgga tgaggatcaa atcttcctac tttggattaa
     9481 caagccatct atcattgttg gtcgtcacca gaacactatc gaagaaatca accgtgatta
     9541 tgttcgcgaa aatggtattg aggtagttcg ccgtattagt ggtggtggag ctgtttacca
     9601 cgatttaaat aacctcaact acacgatcat ctccaaagaa gatgaaaata aggcatttga
     9661 cttcaagagc ttctcaactc cggttatcaa taccctggct caactcgggg ttaaagctga
     9721 gttcacaggt cgtaatgacc ttgagattga tggtaagaag ttctgtggca atgcccaagc
     9781 ctatatcaac ggccgtatca tgcaccacgg ttgcttgctc tttgacgttg atttgtcagt
     9841 cctcgcaaat gcccttaagg tttcaaaaga taaatttgaa tcaaaaggtg tgaaatccgt
     9901 ccgtgcccgt gtaaccaata ttatcaatga attaccaaaa aaaatcacag tcgaaaaatt
     9961 ccgtgattta ctcctggaat acatgaaaaa agagtaccca gagatgactg aatacgtctt
    10021 ttcagaagaa gaattggccg aaatcaatcg catcaaggat actaagtttg gaacttggga
    10081 ctggaactat ggtaaatcac ctgaatttaa cgtccgtcgt ggaaccaaat tcactagtgg
    10141 taaggttgaa gtctttgcta atgttactga atcaaaaatc caagacatca agatttatgg
    10201 tgacttcttt ggtattgaag acgttgctgc agtagaagat gtccttcgtg gggtgaaata
    10261 cgaacgcgaa gatgttctta aggcgctaaa aactattgat atcacacgct acttcgctgg
    10321 tattagccgt gaagaaatcg ctgaagcggt agttggataa atcaaaaaga agttggccaa
    10381 cttctttttt tgatatttat ttacataatt taaaatacgt aaaatcataa actatccaga
    10441 gcattctttt gttcatcact aacaatatgg gtatagaggt cagtgacttg tgtgctagca
    10501 tgtcctagtt ggtgactgac taaaacttgt gatttagtcg catcatagag cctagttgct
    10561 agtgtatggc gcagtttatg gggtgttaca cgcactttaa aatcctctga gtatttagca
    10621 accattttct caacgctaga agcatcgata cgattaggaa cacctctgta gagagttaaa
    10681 aaaagggctg tatctgtttt ttccgtttta tagcgttgat tccgaatggc cagataattc
    10741 tctaaataag gtttagcaaa agcagcgaca ttgactgagt cacgtttgcc accttttcga
    10801 gtaacatcaa taaccatcat ttttagattg agatctctta gatctagatt aacagcttca
    10861 gataagcgaa caccagatgc caagagaagg gcaataatgg ctaaatctcg ttctttattt
    10921 ttgttgaatg atgagagagc tcgatttgaa agctgttgtg ggtgctcttg atcgatataa
    10981 gttagaaaac cttctgtttc atcacctaga aagagttttt gcttgatatt ttcagctctg
    11041 gcagcaaggg tttctttctt tttcttggtt gaaacttttt tcattacatt acgatagaaa
    11101 taaggttccc cctgatcgtt ttcaacctcc tcggttagat acttgtaaag actagaaagt
    11161 gctgataagg ttcgattgat agttgtctgt gaaacaccct gttttgttgt attagcattc
    11221 agcaagggac gttcacgtag ataaaggata aaggattcca tgtctttctt agacatattt
    11281 tccaaaactg ataaaggaat atcggatatt ttatcagcgt ttgaaatacc agacttcaaa
    11341 acccagctga aaaatcggtc atattcctta aggtattcgt acagggttgt aaaactgtag
    11401 ggtacagcca gcttagattg gtagtattcc agaacatacc agggcatgag ttgttttagt
    11461 ttgtcgattc gttccagtaa aatctcacgt ttcatgtatt ttctccataa gtaagtatac
    11521 tagtagtata gcatagactt gtatattttt caagaaaatt atagtttttc agaaagatgt
    11581 tataggagtt tttcaaagtg ataaaaacac ttagacctac aaacaaaaca gaataaggaa
    11641 aataatgaaa atctcaccca ctaaacttct gttaatacta cataactgaa gagctatata
    11701 aggagctatg agatacaaaa cacattgtat aatagattga aactagaata gtacatctgg
    11761 acttctaaaa cattgctaga aattgatttg attgtcctga ttgttttatc ctatttctat
    11821 ttcatttcac tatataattg ctattgtttt ctttttcatg attttaatct tactgtacag
    11881 atttgataca gtaaactcct ttctagcttt atactttatc atttctaact taattatagt
    11941 cttattttta ataaagttca attatttata tgtaaaattc ctcatcagta aaaaataacc
    12001 gatctcattt ctgagaatcg gttttctaaa taaatcaaac cgatcattta cataacataa
    12061 attatgtaaa tgatcatact acaacaacaa atctttgact tttccaattt cactttttgg
    12121 aataaccagg tgaatcatat cacccagata cattctggtt gagccgttaa ctgtttggct
    12181 cttgccatta tggacttgag ttgtgatgag gacgttgtgt ggtaagttga gttcatgaac
    12241 ttgtttccca gcaattttat cagaaactgg tatttcgata agtgtaactt ctccttcgct
    12301 agatacttct tctggaagca ttttttccag catggcttca tagactggcg tacctttgag
    12361 caaatccatg ataatataag aaacaagagt gacaagacca agtggcataa ggttgcgaat
    12421 atctcctacc atctcagtta cgaggatcat agcggttaag ggagcttttg atatggctcc
    12481 aaaatagcca ctcattccta gaatgacaaa tatagggaat tgctcttgac tgacaagtcc
    12541 aagattgaca cagataacac caactaaggc accaagcaaa gaaccaagag ctaaaatggg
    12601 gaggaaaatt cctcctggca gtccacttcc atagctaatc atactccaaa taaagcggat
    12661 taaaaagtaa gctaataaaa cttggaaact aaaattttgt tcagttaaag aaaggacaag
    12721 ctgatttccg ctaccaatga tttgaggtaa gaagattccg actggtatga taaggataaa
    12781 agccaagatg ggataataag ccctatccaa atggattttt tgaccaatca agtcataaac
    12841 tcttccaacg tttaatacag ctttctcata gagaaaacct gaaaatccaa ggaaaattcc
    12901 catgacgaga tatatccaat actgatctag ggtcatggga ggaatgttat ctggcatatc
    12961 caatactggt gtcaaaccga acatgagtag agacacaaag tttgctacga tgctggctgc
    13021 tagagttgag acccagaaaa agcgcgaaaa atggtgatag acttcttcta caacaaagag
    13081 aagtgctgca ataggagcat taaaggctgc ggctaaacct gctgcagctc cactggcaat
    13141 caaggaacgt tcctctactg gactggattt gagccacttg gcaattcctt taccaccaac
    13201 tgctccaagt tgaatactgg gtccctctcg acccagcatg agtccactgg caatagcaag
    13261 aatacctagc acatattttt tccaaagaat gccccaccag ttgagggaca tgaggccttt
    13321 cagttcggct tcgacttgag gaattcctga gcctttaata tctttttctg accgtgttag
    13381 tttggcactg agccaacaga tgagtatata aaacaaaacc agtacaaaaa gattgcgcac
    13441 taagtaccct tgatcttgat aaactccttg tatcatgtgg aagccctttt caattaagaa
    13501 acgaaaggat ccgacgataa ttccaacgat gaggccgaca atgattcctc gaccaacttg
    13561 ggatagtata gtgctggatg caaaggcgaa ttctttctta gaacggacta tttccgactg
    13621 ttcctccatg gtatttcctt tcaattaact ttctttttta cctaaaacca gtgatttaac
    13681 gggttcaaag ctggttcggt gaattggggt aactcctagt tttgtgaggc cttccagatg
    13741 tttagctgtg ccatatcctg cattagtagc gaaatcatag ccagggaact gctgatcgta
    13801 ttctttcatc aattcatcac gtgttacctt ggctactata gatgctgctg cgatagagag
    13861 ggagttggca tctcctttga taatggaggt ttgtgaaatg ggcaagtcca gtttcatggc
    13921 atcaatcaaa aggtgctctg gttgagggct gagctgggag attgcttctt gcatggctag
    13981 tttggttgct tcatagatgt tgacttggtc gatgacctga ttatctatga taccaattcc
    14041 aatcgacaag gcttggtctt gaacggcttg gaaaatctcc agatgtttct ttttaggaat
    14101 tttcttgctg tcgttgagac ctttaatctt acaattttta ggtaaaatga cggccgcagc
    14161 gactacagga ccagcaagag gaccacgacc aacctcatca atacctacaa ttaaggtcaa
    14221 tccttgctta taaagttctt tttcataaga aagcatggat tccaagcgca aattttcatc
    14281 taattcagct tgaatggctc ttttacgctt gctgatttcc ttttgaactc ctgagcgatt
    14341 atccttttca agctctaaaa aaatagggct ttctaactcc ttgactgtca caaggagttc
    14401 tttgatttct ttaatcgttg ccatcgaggt cttccaatgt atctaaggta tagttaccga
    14461 gtttgccatc acggacttcc ttcacgaaga gactgtaaaa acggtcatag tcatcacgga
    14521 aaccgagggc gcgggtcata tccataataa tcacaggcgc ttcttcttca attttcattt
    14581 gtttgaagcg ttcagccagc ttttctggat aatgttcttt gaaataattg ataccaaaaa
    14641 tggtaacctc atccatagga agcaactgat ccttgatagc tccagtcaat gccaacttaa
    14701 gtgcaacagt ttcatcctca aacttaggcc agagaatccc cggtgtatcc aagatttcca
    14761 gatctttatt ggttttaagc cattgttgac cttttgtgac ccctggcttg tttccaacaa
    14821 cagcaatctt tttaccagcc aaacggttca tcagagtgga tttaccagcg tttggaatcc
    14881 cgataatcat ggtacgcaag gtttcaatct gaatcccacg ttctttctgg cgagcaatct
    14941 tatcagccat gagcttcttg gccgcatctg ttacaacttt tacagtcact tgctctttgg
    15001 agttgatagc tagcgtctgg atttcttgtg attcaaaata ctgacgccat tccttggtca
    15061 ttgctggatc agccaagtcg gccttgttta aaatcaagag ttttggttta tcaccaacaa
    15121 tcttggtcaa cataggattt tgactagata gaggcaagcg tgcatctact aaaatcgtca
    15181 caaaatcaac aaattttaaa ttttcctgca cctgtcgacg cgctttagac atgtgaccag
    15241 gaaaccattg aatagtagcc attgagtttt ttcctttcgt agcaaggatt tagatcccct
    15301 attttatttt actatagttt gaacatagag agtcttcaaa tggatgatgt ccaaacagtt
    15361 cttgttttat gacatagaaa tctactttat attatatcat gccttcttta ttttgtccga
    15421 tgatagcctt ttaccctatc ttttacccta tatagaaaaa agccatcaaa tgatgacttt
    15481 tcagagggag caaaaaactg ttcccgtcat attatgaacc aaaagaacta aactaccaac
    15541 agctaatagg cctaaagctg taagcgcaga agttgatgaa cctgttgcag gaagagtttc
    15601 ctgctgataa ataagagcat aacttacttc attatcagta ggaattcctg cttgaatctt
    15661 ggtttgttct tcatcacctt tttaaacttt atttcctaat agtaaacact attttttatt
    15721 ctcaaaaatt gaacttctaa aatcattggt ttgagcaaga taggctttaa agattgctct
    15781 cttcaactta tgaactgcac tgtctatttc tggattataa ttactccaac gtgtacctgt
    15841 agcatcctgc aaaacagctt catccattag tttctgcaat tcatccacat tattgatagt
    15901 ctttgtgcca tagcttggcc atcgttttgt cggatcttta aaggtcacct gcttcaagtt
    15961 tccaaactga tccacccgtt cttggtacat agctgtctta aattctgccc aagttttata
    16021 cttaccatca aatacctttt tcaaaacaag ctcatcggtc accaagcccc gttctttacc
    16081 ataaagattg atagtttgcc cttgttgttt agcatcttct tcgtattgat ttgagatata
    16141 tggtaccata ccatctttaa agcctttagc agctagtagt tcataggcta tacgacgtcc
    16201 cataaggtcg cctggagttc ctttctcact gctcaatgct gaaaagattg gtgcaaagag
    16261 ttttatagta aagtagccat ttctctcata agtgccagcc ttatactcac gagccgaaag
    16321 aatgttattg tcaatcaaac tatcaaagct cgtcaatttt ttagcttcat cttcagtcaa
    16381 atttttcaca acattagtag cataaacatc atttccatct gcaggatctt tcacgtattt
    16441 attctcgatt tttctcaggg ccgtcatttt ctgataagca tctaactgtt tcacgataga
    16501 ttgcccttcg agatattcca acatgtaaac gacatcaaac atattgtgga cgtagttctg
    16561 aagatctgct gcgtcattaa atcttgtagt tggatcaagt acttgcaatc gctgaccttc
    16621 tgtactatct gatgttttat gtttcaagat agagttgatg gtaatggttg catcacttgg
    16681 ttggtctggt gcttgtagta agcctttagc aaagaactca ggtccaagtc cacttcttct
    16741 tccataacct ccaagataaa tgtcctgatc tgagtcatgt gtcatctcat gcgtataagt
    16801 aatggcgccg tccttgtcca acatacgata acccatataa taaacggcat cccctgtagc
    16861 ataagcacca tgtccattat gtccaacctt atttccaaca ggtccaaaga aatgtttcat
    16921 tgcaggattt ggattatcaa aatttgctac ttctgtagcc tttccttcag tatgatcagt
    16981 tccaaattta taggcatcat aaagcaagat atttcgataa agcttttcac gccctttttc
    17041 atctagaata cgataccaat aatcatagtg atctcgttga cgctctgctg tttcgtgagc
    17101 actcttttca acaaagctat taagatcacc atttgcttga tgttctttat tacgatagcg
    17161 atcataagca ccaaaaccta gactagatat ggttgaaatg acaaatacgg atctttctgg
    17221 caaggtaagt agaggtagta ccatattacg gtatttccag ctgtcgctag tgattcgatc
    17281 atagacacca atagaatact tagtaccaac tagtccttgc ttcgttttca cctcttcgat
    17341 attggatttt tcttcgacaa tgtaagcctt agtctgtgat ttaaaccagt cattattggt
    17401 tttgtctggt agaaagactt ttcggtaatt ttccaacgtg ctaaacaaat ctgtcgttcc
    17461 atgatggctg gcaagactga tagcataagt atcgacattg tttttagcaa gaagattgtt
    17521 aaagccagat ttacctaact caatcagagt atctaatggt gaggtatttc ctttaccaaa
    17581 gaagtccaga tgatacataa ctaggttttt gacattcact tgaccatagc taaagttata
    17641 ccaacgttct aaataagtta aaccgagtag taaggcttcc ttattgttct tgattttatc
    17701 tacaagatag cctctggtaa ctgggttgtc accagcaagt ccagcatctg cagacaagag
    17761 ttttttcaaa ctgtttgcca aatcttgctt tgttttggta aactggtctt ccatatagag
    17821 ctcagtttgc ttgacctctg gagaaattcc gagtgtcttt ctgatagctt ctgaatcgta
    17881 ggcaacctgc tgtaattcag gtaaaacttg attgatgata gagtcttggt catacaagaa
    17941 ttggtttggc gtatagagaa gaccagtatc tcctagacta tattctgcta acttagcaaa
    18001 atcagcctgg tacctgagat caaacttttc agatgaatgg tccttgtagt gaagcaagag
    18061 tttgtttgca gtctgtttgt tggaaataat atctgtgatt acttggtcat ccttcatcat
    18121 aactgcagac aagagttctt tttgatataa gatactgttc tccttaacca ggtttccgta
    18181 tttcacgatg gtcgccttgt tatagaaagg taacaatttt tcaatgttct tataaaccaa
    18241 agcacggttg gcttgataat gggctatctt agaaaaatca ctgtctttct taccgcttgt
    18301 tgagaggggt ttcactattg gtggagtgag aagattgatt tctgcttttt tgcttgcaat
    18361 ttgagaagca tctagcattg ttcctctttc ctcaaaggat tctttgctga cgacctcatc
    18421 cttctctaaa gtgacattga aaactttatt cgctttatta ctaaatgcat cagtaatttt
    18481 cattccatta taatggtaac cactaatggc atttccatta gttacattga catcactaag
    18541 cacattagtc aatcttccag catgattttc actatttgat tcacgatccc ataagttacc
    18601 tgctatacca gcaacttttc caaaacgttg actattatta atatcccctt cagaatagct
    18661 attctgaata tgcgcatctt tgtctacaag accagcgata cctccaacgg tctggtcaga
    18721 actatttgta tttgatgaaa tgaccactgt cgcttttgac ttagtcagtg aagctttgct
    18781 tcctgtcaag tgaccgacca ggccaccgat attataggaa gcggttgttt cataggtatt
    18841 gacaattctt cccttgaaac tactctctgt gatgcttgat tgatctgcct tagccaacaa
    18901 accaccgata ccacgttcac cggcaagtac accatccaca tgaacttgct taatttttgt
    18961 gttattctga gcttcatttg ccagtgaacc gatatcatct ttccctgaaa tagagacatt
    19021 tttcagactc aacttttcta ttgtggcccc tctcaagctt tcaaaaagag gctttttcaa
    19081 gttgtaaata gcataatgct taccatcttt ttcaccaatc aactgaccag taaaggttcc
    19141 cttgatatag gatttatcat cagtactaag ctccacttcg ttagcattca ggctagctcc
    19201 taaatgatag gttccagaga gattttggtt tatagctttg accagattac taaaggaagt
    19261 aaagtttgtt gtttcttctg ttcccttctt agctagatag aaggtaaaat tatctttata
    19321 tctgctttct atctcctgct gaagcttctc tacttttgct gtgattttat aaaggatttt
    19381 atcatttttt ctttcctctg atattgatgc tactggtagg tatacatctt tgaatgaaga
    19441 agatttcact ttaacaaagt agctatttgg attgcttgga acttgttcta acgaaatgtg
    19501 ttgtttataa gtaccatttg acaaactgta taactctagg tcggaaacat ttcttaattc
    19561 aagtgttttc tctggatctt ctaccttttt atcggggtct agttcatttt cttgtttaat
    19621 ttcttcgttt ccatttgaat tggatgtgtt tgatttggtt gaaacattct cagttgaatt
    19681 tccgtttgat ggttctggtt ctgtttgtcc attctctgat gttgtattac ctgaattttc
    19741 tggttgattt gattcttcaa ctggtggttt tgaatcacta ggtttattgg atacttcccc
    19801 agtattttcg ctagatgtat ctggtgatac tttctctgaa ttcgttgttg attcttctgc
    19861 aggttgaact ggattttctg ctccttgaat tgaggttcct tctgtagtac cttcatttgg
    19921 atttactggt gtttcttctg ttggttttac tggaacttct tcagtttttt ctggaccttg
    19981 ttctttggtc ttctcaaccg gagtttcagg ttttacttgc tcaatattac ccttatattc
    20041 tggaagcggt gctacctgtt taggttcacc tttatcactt accacagtat ctgacgactc
    20101 tggttgaacc tcagtctcac ctttgtcggt tacgactgct tccgataacg ctggttgaac
    20161 ttctggtacg cctttatcac ttactacagc ttcgggtaat tcaggttgga cagcgggctc
    20221 acctttgtcg gttacgactg cttccgataa cgctggttga acttctggta cgcctttatc
    20281 acttactact gcttcgggca actcaggctg aattgcgggt tcaacaatag ctccagactg
    20341 tacgtcctta tgttctacac cagtctcagg ttgttccttt ataacttgag tttttttagt
    20401 acctttttcg actattcttg gactaggcgc agtcgttgaa gttgaaacaa tttctcgcga
    20461 aacttcttcc ttgtttacag agaatattct gacgatttca actttcttac ctaatttacc
    20521 ttcttgtttt actcttacag ttccttcagc taaatcagga ttttcttgaa tttcttcttg
    20581 aaaatctatt tttgtctcta tagtttcctc acgatataag agttcaggtt tgttcaattg
    20641 acctgataaa acttcatcct gtggatttaa tgtatttacc ccagtctttt cttttggaga
    20701 aatcttctcc tctttcttcg tttctagatt cttatgttcg gctaattgtt cttgagaatc
    20761 tgaagattgt ttctcttctt ttcttggatt gattaattta gtagagaaag gtttttcaac
    20821 tacttgaact tctgtcggct tagttgaaga aacaggtgtt tgttcctgaa tagcttgtac
    20881 tgttgatgga tggtctacaa aatttggtgt aacattataa tccacctttt gttgttttgt
    20941 aggagtggct gctgattttt cttgattact tacttcaaaa tcagaagtcg tttttccctc
    21001 tttgatatat ccaatataag tgtaacctga aatctcttta ggaagaggta atttttctcc
    21061 agagatcaat tcatagtccg tattgtaatt tagcaaaaga tgattttcta aagcatggac
    21121 tgaaactaag acaccatttc ctattcccgc aaccaatact aaatgtaata ccgttttatt
    21181 cttaaccttt ttcttggaaa cagcaaaaat taaaattccc agagcagcta agctagcacc
    21241 agcaactagg gcttgcctct cattcttgct tccagtattt ggtaattccg ccagttgatt
    21301 ttgagaattt aacttataaa caagataata agtttcatca tcattctcca cgtatgtcgg
    21361 aatatcatag acaagctgct tcttttcttc tgatgatagc tctgaatctg ccacatattt
    21421 atagtgaact cccgcagttt cttgagcatc cacagatgaa ctagctaata cagacataaa
    21481 aaataaactt gaaatcgttg cagatacaag tcctactgat aattttctaa atgaaaaacg
    21541 ctcttgtttt tcaccaaaat acttttccat tattcctcct tgaaataaaa tttatatatg
    21601 ttaca
//
LOCUS       DAVKAU010000028        20868 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVKAU010000028 DAVKAU010000000
VERSION     DAVKAU010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20868
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.028"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            77..310
                     /locus_tag="VWX48_001271"
     CDS             77..310
                     /locus_tag="VWX48_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family peptide pheromone/bacteriocin"
                     /protein_id="HEU9171897.1"
                     /translation="MDTKMMSQFSVMDNEMLVRTEDGDVSDIYRGYANQRSPFASYPS
                     ILKNSGPFPVSGYCLRGYHDRGYIGAGFHLCGI"
     gene            342..1031
                     /locus_tag="VWX48_001272"
     CDS             342..1031
                     /locus_tag="VWX48_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9171898.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1073..1306
                     /locus_tag="VWX48_001273"
     CDS             1073..1306
                     /locus_tag="VWX48_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171899.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            1457..2068
                     /locus_tag="VWX48_001274"
     CDS             1457..2068
                     /locus_tag="VWX48_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9171900.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLISSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            2230..3024
                     /locus_tag="VWX48_001275"
     CDS             2230..3024
                     /locus_tag="VWX48_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU9171901.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3021..3656
                     /gene="trmB"
                     /locus_tag="VWX48_001276"
     CDS             3021..3656
                     /gene="trmB"
                     /locus_tag="VWX48_001276"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU9171902.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            3782..4261
                     /gene="rimP"
                     /locus_tag="VWX48_001277"
     CDS             3782..4261
                     /gene="rimP"
                     /locus_tag="VWX48_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU9171903.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            4305..5441
                     /gene="nusA"
                     /locus_tag="VWX48_001278"
     CDS             4305..5441
                     /gene="nusA"
                     /locus_tag="VWX48_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU9171904.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            5463..5756
                     /locus_tag="VWX48_001279"
     CDS             5463..5756
                     /locus_tag="VWX48_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU9171905.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            5749..6048
                     /locus_tag="VWX48_001280"
     CDS             5749..6048
                     /locus_tag="VWX48_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU9171906.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6065..8857
                     /gene="infB"
                     /locus_tag="VWX48_001281"
     CDS             6065..8857
                     /gene="infB"
                     /locus_tag="VWX48_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU9171907.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9108..9458
                     /gene="rbfA"
                     /locus_tag="VWX48_001282"
     CDS             9108..9458
                     /gene="rbfA"
                     /locus_tag="VWX48_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU9171908.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            9737..10516
                     /locus_tag="VWX48_001283"
     CDS             9737..10516
                     /locus_tag="VWX48_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171909.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            10518..10700
                     /locus_tag="VWX48_001284"
     CDS             10518..10700
                     /locus_tag="VWX48_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171910.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(11057..11131)
                     /locus_tag="VWX48_001285"
                     /pseudo
     CDS             complement(11057..11131)
                     /locus_tag="VWX48_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11162..11395
                     /locus_tag="VWX48_001286"
     CDS             11162..11395
                     /locus_tag="VWX48_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU9171911.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            11395..12729
                     /locus_tag="VWX48_001287"
     CDS             11395..12729
                     /locus_tag="VWX48_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU9171912.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYEYMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            12739..12993
                     /locus_tag="VWX48_001288"
     CDS             12739..12993
                     /locus_tag="VWX48_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU9171913.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            13089..13484
                     /locus_tag="VWX48_001289"
     CDS             13089..13484
                     /locus_tag="VWX48_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9171914.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            13896..14345
                     /locus_tag="VWX48_001290"
     CDS             13896..14345
                     /locus_tag="VWX48_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEU9171915.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQISILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPEFLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            14332..14892
                     /locus_tag="VWX48_001291"
     CDS             14332..14892
                     /locus_tag="VWX48_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171916.1"
                     /translation="MARTELSDKIETERLVLRVRTVADAEDIHAYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIAGSVDFNHRHEDDVLEIGY
                     TLPPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEVI"
     gene            14892..15470
                     /locus_tag="VWX48_001292"
     CDS             14892..15470
                     /locus_tag="VWX48_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9171917.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            15463..18114
                     /locus_tag="VWX48_001293"
     CDS             15463..18114
                     /locus_tag="VWX48_001293"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU9171918.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRVLEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNDLAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            18184..18939
                     /locus_tag="VWX48_001294"
     CDS             18184..18939
                     /locus_tag="VWX48_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU9171919.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            19216..20019
                     /locus_tag="VWX48_001295"
     CDS             19216..20019
                     /locus_tag="VWX48_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU9171920.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(20135..20868)
                     /locus_tag="VWX48_001296"
                     /pseudo
     CDS             complement(20135..20868)
                     /locus_tag="VWX48_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         6273 a         3905 c         4713 g         5977 t
ORIGIN      
        1 ttttctcttt attgcttatg tttttttgat aatttttata ttaaacttgt tccgtaactg
       61 aaaagtgata tactatatgg atacaaaaat gatgtcacaa ttttctgtta tggataatga
      121 aatgcttgtt cgtacagagg atggggatgt ctctgatatt tatagagggt acgctaatca
      181 gagaagtcca ttcgcttctt acccttctat attaaaaaat tcaggtcctt ttccagtaag
      241 tgggtactgc ctgcgtggtt atcatgaccg tggttatata ggagcaggtt ttcatttatg
      301 tggaatatag gctgaaatac aagaaatgag ggaggatttc tatgaaaaag tatcaacttc
      361 tattcaaaat aagtgcagtc ttctcttact tatttttcgt atttggtctt tctcagctga
      421 cgcttatcgt ccaaaattat tggcaatttt cttcccagat tggtaatttc gtctggattc
      481 aaaatatctt gagtttactt tttattggag tcatgattgt ggttcttgtt aagacaggcc
      541 atggttatct cttccgcatt ccaagaaaaa aatggctttg gtattcgatt ttgacagtat
      601 tagtggtagt gttccagatc tcttttaacg ttcagacagc taaacatgtt cagtcaactg
      661 cggaaggttg ggctgtattg attggttata gtgggactaa ctttgcagag ctaggtattt
      721 atatagccct gttctttctg gttccactga tggaagagtt aatctataga ggattactgc
      781 aacatgcttt ctttaagcat tcgcgatttg gtcttgattt gcttcttcct tctattttat
      841 ttgctctccc tcatttttca agcctgccta gtctgttaga tatcttcgtc tttgcaacag
      901 ttggaatcat ctttgctggt ttgacccgct ataccaagag catttatcca tcctatgcgg
      961 tgcatgtgat caataatatt gtagcgacct tcccgttttt gctcactttt ctacataggg
     1021 tcttggggta aaaaaacaaa aggcttgctt ttcagccata gaggaggtca tcatgtataa
     1081 acacttattt ttcctagatt ccaaaacttt agatcggttg acaccctata ttctagtctt
     1141 ggcttctgac accattgctt ttaatgtttt tgtgctaacc tttgtatctg cggtggtttt
     1201 taatttccta aattccatgc tagctttaat ggctatattc ataggggctg gctatgtggt
     1261 cggattttgg ttactaatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag
     1321 gctgtacttg agtacggcaa ggtgacgttg acgtggtttg aatttgattt tcgaagagta
     1381 taaaatggtt tgttttggaa aggctagaac taaagaatga cgtgtaggaa gtctgtttgt
     1441 tgaggaggat aattttatgg agttttttga taaatttcat gccttgtgtt ttggattttt
     1501 agtactaata attgtcatta tagttcctta tacgattaac catggggatt tttttcaaaa
     1561 tgaatctgca ttgattcttg taagtcttct tgtaacctcg ctgagtgttg cttatgctag
     1621 aaagtttgaa atgatttctt ttgggatgtt aagcaagaaa caacttttgc ttttcattgc
     1681 aatctttctt ctaagtgtac ttgagacgct ggtttatatt catttcttcg ctgtttcttc
     1741 tggctcaggg gtccaacact tggcggaagt cagcagagga atttccctgt ctttgatttt
     1801 gactacctca gtttttggcc ccatccagga ggaactcatt ttcagaggac ttcttcaagg
     1861 tgcggttttt gacaattctt ggttagggct tgtgctaatt tcctctctct tttctttcat
     1921 gcatggacct tctaatgtcc cttcgtttat tttttatcta cttgggggct tgttgctggg
     1981 ccttgcttat aaaaagagcc aaaacttatg ggtttctact ctagtccaca tgttttacaa
     2041 cagttggcca ctcctatatt atttataaaa attatgaaaa ggtaagtagg agattgtgct
     2101 tacctttttc tttctataat gataacccaa accactccag aggcttttct ttgagaatcg
     2161 ggttagagtg gttgacgaat aggccaaaaa ctagtagaat agtaaggaaa ctttatacgg
     2221 aggaaagaaa tggatttggg tgataatgag ctaacactga ctcccatacc tgggaaaagt
     2281 ggcaaggctt atatgggtag ctatcctgat gggaagcgca tctttgtaaa aatgaacacc
     2341 tctccaatcc tacctggtct agctagagaa caaattgctc cacaattatt atggagtcgt
     2401 cgtttggcag atgggcgtga tatgtgtgct caagaatggt tgacaggcaa gatattgacc
     2461 ccctatgata tgaatcgtaa gcaaatcgtc aatattttaa cccgtcttca tcgctcacgt
     2521 ccgttgatga cacaattgag tcgtttgggc tatgccatgg aaacacctgt agatttacta
     2581 cagtcttggc aggaaacggc tccagatgct ttgcgtaaaa atcattttat cagtgaagtg
     2641 atggctgatt tacgtcagac tattccagga tttagagagg accatgcgac cattgtccat
     2701 ggagatgtac gacatagtaa ttggattgag acagatagtg gcttgattta tttagtagat
     2761 tgggattcgg ttcgcttgac cgatcgcatg tttgatgtgg cccatatgct ctgccattat
     2821 atttcagaac atcagtggaa ggaatggttg acctactacg gttacaagta caatcaaacg
     2881 gtattaagta aattgtattg gtatggtcaa ttgtcttatt tgagtcagat ttccaagtat
     2941 tatatgaacc aagatttaga aaatgtcaat cgggagattc atggtttgcg tcatttccga
     3001 gacaagtatg gaaagagaag atgagagtta gaaatcgtaa aggggcaaca gaattactag
     3061 aggcaaatcc ccagtatgtg gtcctcaatc ccttggaagc caaggcaaaa tggcgggact
     3121 tgtttggcaa tgataatccc attcatgtgg aagttggaag tggaaagggt gcctttgttt
     3181 caggtatggc caagcaaaac cctgacatca actatatcgg gattgatatt caaaagtctg
     3241 ttttgagcta cgctttggac aaggtgcttg aagctggagt gtctaacatc aagctcttgt
     3301 gggtagatgg ttctgacttg actgactact ttgaagacgg tgagattgat cgcttgtatc
     3361 tgaacttttc agatccatgg ccgaaaaaac gccatgaaaa gcgtcgtttg acctacaaga
     3421 cctttttgga taccttcaaa cgtatcttgc ctgaaaatgg agaaattcat ttcaagacgg
     3481 ataaccgtgg cttgtttgag tacagtttag tgagcttttc tcaatatggc atgaaactca
     3541 atggtgtctg gttagatttg catgccagtg attttgaagg caatgtcatg acagaatacg
     3601 agcaaaaatt ctcaaacaag gggcaagtta tctaccgagt tgaggcagaa ttttaataga
     3661 tagcctaaaa ttaggctgta caagtgcttt tgctttacat aggttggcaa acgtgctata
     3721 ctgataataa gaatatgaaa agtgaggcgg ggaaatatct tcgcctcttg cttatgagga
     3781 ggtggacgca atcgcaacaa tcgtagaatt agtcagagaa gttgtagaac ctgtcataga
     3841 agctcctttt gaactcgtgg atatcgagta tggaaagatt ggcagtgaca tgattctcag
     3901 tatttttgta gataaacccg aaggaattac cttgaacgac acggcagact tgacagaaat
     3961 gatcagtcct gtcctagaca ccatcaagcc agatcccttc ccagaacaat atttcctaga
     4021 aattaccagt ccaggtttgg aacgtccttt gaaaaccaag gatgccgtcg ctggagcggt
     4081 tggaaaatac atccatgtcg ggctctacca agccatcgat aagcaaaagg tctttgaagg
     4141 aaccttgttg gccttcgaag aggacgagtt gactatggaa tatatggaca agacgcgtaa
     4201 gaaaaccgtc caaattccat acagtttagt atcaaaagca cgtttagcag ttaaattata
     4261 gaaaaagaaa ggatagcttt tgaggattca aaagtgaaga aaacatgagt aaagaaatgc
     4321 tagaggcctt ccgcattttg gaagaagaca agggaatcaa aaaagaagat atcatcgacg
     4381 cagtagtaga gtcgcttcgt tccgcttatc gcagacgcta tggtcagtca gacagcgtag
     4441 ctattgactt caacgaaaaa acaggtgact ttacagttta tactgtccgt gaagttgttg
     4501 atgaagtatt tgatagccgt ttggaaatca gcttgaaaga tgctcttgct attaattcag
     4561 cttatgaact tggagacaaa atcaagtttg aagaagcacc agctgagttt ggtcgtgtag
     4621 cagcccaatc tgccaaacaa accatcatgg aaaaaatgcg caagcaaaca cgtgccatca
     4681 cttacaatac ttacaaagaa catgagcaag aaatcatgtc tggtacagta gaacgctttg
     4741 acaaccgctt tatctatgtc aaccttggta gcatcgaagc ccaattgtca aaacaagacc
     4801 aaattcctgg agaagttttt gcttctcatg atcgtatcga agtttatgtt tacaaggttg
     4861 aagacaaccc tcgtggtgtg aacgtctttg ttagccgtag ccatccagaa atgatcaaac
     4921 gtttgatgga gcaagaaatt ccagaagttt atgatggaac tgttgaaatc atgagcgtgg
     4981 ctcgtgaagc aggtgaccgt acgaaggttg ctgttcgtag ccacaatcca aacgtggatg
     5041 ctatcggtac aatcgttgga cgtggtggtg ctaatatcaa gaagattact agcaaattcc
     5101 acccagctcg ttacgatgct aaaaatgacc gcatggtacc aatcgaagaa aatatcgatg
     5161 ttatcgagtg ggtagcagat ccagctgaat ttatctacaa tgccatcgct cctgctgagg
     5221 ttgaccaagt tatctttgat gaaaacgaca gcaaacgtgc cttggtggtt gttccagata
     5281 acaagctttc tcttgccatt ggtcgtcgtg gacaaaacgt gcgcttggcg gctcacttga
     5341 ctggttaccg tatcgatatc aagtctgcta gcgaatttga agccatggaa gacgctgctt
     5401 cagtagagtt ggaagtagaa aacgatactg tagaagaata aaagctgcta gaggagggaa
     5461 agatgaaaac aagaaaaatc cctttgcgca agtctgttgt gtctaacgaa gtgattgata
     5521 agcgtgattt gctccgcatt gtcaagaaca aggaaggaca agtctttatt gatcctacgg
     5581 gcaaggccaa tggccgcggc gcttatatca aactagacaa tgcagaagcc ctagaggcga
     5641 aaaagaagaa ggtctttaac cgcagcttta gcatggaagt ggaagaaagc ttttatgacg
     5701 agttgatcgc ttatgtggat cacaaagtga aaagaagaga gttgggactt gaataagcaa
     5761 aagataagta atctcttggg gcttgctcag cgagcagggc gcatcatatc gggtgaagaa
     5821 ttggtggtca aggccattca agacggcaag gccaagttgg tctttctagc tcatgatgct
     5881 ggacccaatc tgaccaagaa gattcaagat aaaagtcatt attatcaagt agaaattgta
     5941 accgtgtttt caacactgga attaagcata gcagtcggga aatcgagaaa ggttttggct
     6001 gtaacagatg ctggatttac aaagaaaatg aggtctctta tggaatagaa gaggaggaca
     6061 tgatttgtct aagaaaagat tgtacgaaat cgcaaaagaa cttggaaaag aaagtaaaga
     6121 agttgtagcg cgtgcaaaag agttgggctt ggatgtgaaa agccactcat caagtgtgga
     6181 agaagctgtc gctgcaaaaa ttgctgccag ctttaagcct gcagctgctc cgaaagtaga
     6241 agcaaaacct gcagcaccaa aagtaagtgc agaaaagaaa gccgaaaaat ctgagccagc
     6301 taaaccagct gtagctaagg aagaggcaaa accggctgag ccagttgctc cgaaaacaga
     6361 aaaagtagca gcgaaaccgc aaagccgtaa tttcaaggct gagcgtgaag cccgtgctaa
     6421 agagcaggca gaacgacgta agcaaaataa gggcaataac cgtgaccaac aacaaaacgg
     6481 aaaccgtcag aaaaacgacg gacgtaatgg tggaaaacaa ggtcaaagca accgcgacaa
     6541 tcgtcgcttt aatgaccaag ctaagaagca gcaaggtcag caaaaacgta gaaatgagcg
     6601 ccgtcagcaa gaggacaaac gttcaaatca agtggctcca cgtattgact ttaaagcccg
     6661 tgcagcagcc ctaaaagcag agcaaaatgc agagtacgct cgttcaagtg aggaacgctt
     6721 caagcagtat caggctgcta aagaagcctt ggctcaagct aacaaacgca aggaaccaga
     6781 ggaaatcttt gaagaagcgg ctaagttagc tgaacaagca cagcaagttc aagcagtggt
     6841 tgaagtcgtc cctgagaaaa aagaacctgc agtggataca cgtcgtaaaa aacaagctcg
     6901 accagacaaa aatcgtgacg attatgatca tgaagaagat ggtcctagaa aacaacaaaa
     6961 gaatcgaagt agtcaaaatc aagtgagaaa tcaaaagaat agtaactgga ataacaacaa
     7021 aaagaacaaa aaaggcaata acaagaacaa ccgtaatcag actccaaaac ctgttacgga
     7081 gcgtaaattc catgaattgc caacagaatt tgaatataca gatggtatga ccgttgcgga
     7141 aatcgcaaaa cgtatcaaac gtgaaccagc tgaaattgtt aagaaacttt tcatgatggg
     7201 tgtcatggcc acacaaaacc aatccttgga tggggaaaca attgaactcc tcatggtgga
     7261 ttacggtatc gaagccaaac aaaaggttga agtggataat gctgacatcg aacgtttctt
     7321 tgtcgaagat ggttatctca atgaagatga attggttgag cgtccaccag ttgttactat
     7381 catgggacac gttgaccacg gtaaaacaac ccttttggat actcttcgta actcacgtgt
     7441 tgcgacaggt gaagcaggtg gtattactca gcatatcggt gcctaccaaa tcgtggaaaa
     7501 tggtaagaag attaccttcc ttgatacacc aggacacgcg gcctttacat caatgcgtgc
     7561 gcgtggtgct tctgttaccg atattacgat cttggtcgta gcggcagatg acggggttat
     7621 gcctcagact attgaagcca tcaaccactc aaaagcagct aacgttccaa tcatcgtagc
     7681 tattaacaag attgataaac caggtgctaa cccagaacgc gttatcggtg aattggcaga
     7741 gcatggtgtg atgtcaaccg cttggggtgg agattctgaa tttgttgaaa tctcggctaa
     7801 attcaaccaa aatatcgaag aattgttgga aacagtcctt cttgtggctg aaatccaaga
     7861 actcaaagca gacccaacag ttcgtgcgat cggtacggtt atcgaagcgc gcttggataa
     7921 aggaaaaggt gcggtcgcaa cccttcttgt acaacaaggt accttgaatg ttcaagaccc
     7981 aatcgttgtc ggaaatacct tcggtcgtgt ccgtgctatg accaacgacc ttggtcgtcg
     8041 tgttaaagtt gctggaccat caacaccagt ctctatcaca ggtttgaacg aagcaccgat
     8101 ggcgggtgac cactttgccg tttacgagga tgaaaaatct gcgcgtgcag caggtgaaga
     8161 gcgtgccaaa cgtgccctca tgaaacaacg tcaagctacc caacgtgtta gccttgaaaa
     8221 cctctttgat acccttaaag ctggggaact caaatctgtt aatgttatca tcaaggccga
     8281 tgtacaaggt tctgttgaag ccctttctgc ctcacttcaa aagattgacg tggaaggtgt
     8341 caaagtgact atcgtccact cagcggtcgg tgctatcaac gaatcagatg tgacccttgc
     8401 cgaagcttca aatgccttta tcgttggttt caacgtacgc cctacaccac aagctcgtca
     8461 acaagcagaa gctgacgatg tggaaatccg tcttcacagc attatctaca aggttatcga
     8521 agagatggaa gaagctatga aagggatgct tgatccagaa tttgaagaaa aagttattgg
     8581 tgaagcggtt atccgtgaaa ccttcaaggt gtctaaagtc ggaactatcg gtggatttat
     8641 ggttatcaac ggtaaggttg cccgtgactc taaagtccgt gttatccgtg atggtgtcgt
     8701 tatctatgat ggcgaactcg caagcttgaa acactacaaa gatgacgtga aagaagtgac
     8761 aaacggtcgt gaaggtggat tgatgatcga cggctacaat gatattaaga tggatgatgt
     8821 gattgaggcg tatgtcatgg aagaaatcaa gagataagat tttttgctcc tttcttaggt
     8881 ggtgagggac gcaagcaaac cgatggtttc attgcttatt tttgagccta gggtctcaaa
     8941 aatcccctgt gatgggactg ataaatcagt tccatcactt tcaccacggc gaaagaagca
     9001 gatgacttca aattgaactt cgtttcaatt taaactgaaa atcaagaagt ttaaaatagc
     9061 taggtctgct ggcctagctt ttggttcaaa gtagagaaag gaatatcatg gcaaatcatt
     9121 tccgtacaga tcgtgtgggc atggaaatca agcgtgaagt caatgagatt ttgcaaaaga
     9181 aagtccgtga tccacgtgtc caaggtgtga ccatcacaga tgttcagatg ctgggtgact
     9241 tgtctgttgc caaggtttat tacaccattt tgagtaacct tgcttcggat aaccaaaaag
     9301 cccaaatcgg gcttgaaaaa gcaactggta ccatcaaacg tgaacttggt cgcaatttga
     9361 aattgtacaa aatcccagat ttgaccttcg tcaaagacga gtccatcgag tatggaaaca
     9421 agattgacga gatgctacgc aatctggata agaactaaag aagaggggtt gcccctcttt
     9481 tttggtggag gaaaataggt tgaatttgaa atggaaaaat attcttttaa aatatattga
     9541 aactagaata gtacgcctct acttctaaaa cattgttaga aatcgatttg actgtcctga
     9601 tcgatttgtc ctgttcttgt ttcatttcac tataaaaaag gggttctgta ttttttaatg
     9661 ttatctaatt agaaaatgct ttttttgtag gaaatataat atgataaggt gcaaaaaaga
     9721 aataaggagt ttgtatatgg ctgaacaaga cttagctatg caagtattgc aacaagtggt
     9781 gaaactacct gttgttaagg ttgatcgttc gaaattttta gtggataagt tttccaaaga
     9841 attgggtcca caggacattc ctaccttatt ggaacaaggt ccaacgtctc tcttatctca
     9901 agaaatctta gatcgagtgg ctaatgcctg tattagggat aatgttttat tagcgagtgg
     9961 gacttctgtt ttggcaggat tacctggagg gcttgctatg gcaattacca ttccagctga
    10021 tgtggctcaa ttttatggtt tctctctgaa attggcccaa gaattaggtt atatttatgg
    10081 ttatgaggat ctttgggctt cacgcgatga gttgagtgaa gatgctcaaa ataccctttt
    10141 gctttatcta ggcgtcatgt tgggggtgaa tggaactgct gctttgctac gtgctggtgg
    10201 tataacaatt gccaaacagg taatgaaaac agtacctaat aaagctttaa caaagacgct
    10261 ttggtatcct attttgaaaa aagtcttaag aatatttggt gtgaatctta ccaagggagg
    10321 gctggccaaa ggaatgggga aatttattcc tatcttgggt ggtatcattt caggtggttt
    10381 aacctttgca actatgaaac cgatgggtga aagcttgcag aaagaattgt ccaagctagt
    10441 taactatagt gaagttcaat atcaagaaga tgttgaaaca atccgaaaag aggctgaaat
    10501 catcgaagga gagtaatatg ggactcataa aaactctagc taaaatttat ggtaattact
    10561 ttttgaccgt gcaaggtgta aaagtaatga aaacgataaa gaaagatgac catgtcgttg
    10621 ttggtctggg aaaactcttt attgcagata agctaatgga tacggctcgg tggctcatta
    10681 agccagagga taaaaaatga aatttttctg gggacttctt gccattattt ttatcaaacc
    10741 gattattggg attgtgaaat tcttttggat gatcatctct tttgcagtcc aattgctgtt
    10801 ttacaagata gtgtttaaga tattggattg gctctttaaa cttatctaga tggtaatcca
    10861 agtcgcagag aactagcagg aactccactg ctagtttttt attctctttc catatggtat
    10921 aatataagca gtaaaatcat tttatactct tcgaaaatct cttcaaacca cgtcagcttc
    10981 accttgcagt atatatgtta ctgacttcgt cagttctatc cacaacctca aaacggtgtt
    11041 ttgagctgac ttcgtcagtt ctatccacaa cctcaaagca ctgttttgag caacctgcgg
    11101 ctagcttcct agtttgctct ttgattttca ttgagtatta gaacatacaa tggaggtcgt
    11161 catggacaat atcatcgatg tgtcaattcc tgttgcagaa gtggtggaca agcatccaga
    11221 agtcttggaa attctagtgg agttgggttt taaacccctt gccaatccct taatgcgcaa
    11281 tacagttggt cgtaaagtat cacttaaaca gggttctaag ctagcaggaa ctcctatgga
    11341 caagattgta cgcacactgg aagcgaatgg ctacgaagtg attggattag actaatggca
    11401 gatgaacgga ttcatgtcct acgggatatt ttgttagaat tgcacaatgg cgcctctcct
    11461 gagtcggttc aagagcgctt tgatgcgacc tttgcgggtg tctcagccat cgagatttcc
    11521 cttatggagc acgagctgat gaactcagac tcaggtgtca cctttgaaga tgttatggaa
    11581 ctctgtgatg tccatgccaa tctttttaaa aatgctatca aaggtgtcga agtttcagat
    11641 actgagcatc caggtcaccc agttcgtgtc ttcaaagaag aaaatctggc tctccgtgcg
    11701 gccttgattc gcattcgtag attgttagat acctatgagt atatggaaga cgaggaaatg
    11761 ctggcggaga tgcgtaaggg tttggtgcgt cagatgggac ttgtgggtca atttgacatc
    11821 cattaccaac gtaaggaaga actcttcttt cctatcatgg agcgctatgg acacgattca
    11881 cctcccaaag ttatgtgggg agtggatgat cagattaggg aactctttca aacagctcta
    11941 acgacagcca agtcactacc agaagtgtca attagcagtg taaaggaagc ttttgaagct
    12001 tttgcgacag agtttgaaag tatgattttc aaggaagagt ccatcctcct catgattctc
    12061 cttgagtctt ttactcagga tgactggctt cagattgcgg aggagagcga tgcctatggc
    12121 tatgccatca tccgtccgtc agagaaatgg gtgccagaac gacagagctt tattgaggaa
    12181 aagattgcag aggagcctgt acagctagat acggcagaag gtcaagttca acaagtcata
    12241 gatacgccag aaggccattt taccattacc tttaccccta aggaaaagga agctgtgctg
    12301 gaccgccata gtcaacaggc ttttggtaat ggctatcttt cagtcgagca ggccaatctc
    12361 atcctcaatc acctccctat ggagattacc tttgtcaata aagaagatat tttccagtat
    12421 tacaatgaca atacgccagc tgatgagatg attttcaaac ggacgccgtc ccaagtcggg
    12481 cgcaatgtcg aactctgtca tccgcctaag tatttggaca aggtcaaggc tatcatgaag
    12541 ggacttcgtg agggaagcaa agacaagtat gaaatgtggt tcaagtctga gtcgcgaggt
    12601 aagtttgtcc acatcaccta tgctgcagta cacgatgaag acggagaatt ccaaggagtg
    12661 ttggagtatg ttcaggatat ccagccctac cgtgagattg atacggacta ttttcgtgga
    12721 ttagaataag gagaaaaaat gagttacgaa caagaattta tgaaggaatt tgaagcttgg
    12781 gtcaataccc aaatcatgat taacgacatg gcgcacaagg aaagccaaaa agtttacgaa
    12841 gaagaccagg acgagcgtgc caaagatgcc atgattcgct atgagagtcg tttggatgct
    12901 tatcagttct tgcttggtaa gtttgaaaac ttcaaagtag gcaagggatt ccatgatttg
    12961 ccagaaggct tgtttggtga gcgaaattat taaacgagaa agattcttga tttttcacta
    13021 aaatcttgat agaatgttta tgttaaatcc ttgtcagagc agggattttt tattgaaagg
    13081 attttatcat gtcaaagaaa ctcaatcgta aaaaacaatt acgaaatggc ctccgtcgcg
    13141 caggtgcctt ttcaagtact gtgactaagg ttgtagatga gacaaaaaaa gtcgtgaagc
    13201 gtgcagaaca gtcagcaagc gcagctggta aggctgtttc taaaaaagtt gaacaagcag
    13261 tagaagctac caaagagcaa gctcaaaaag tagctaattc tgtagaagat tttgcagcaa
    13321 acttgggtgg acttccactt gatcgtgcca agactttcta tgatgaagga atcaagtctg
    13381 cttcagattt caaaaactgg actgaaaaag aactccttgc cttgaaagga atcggcccag
    13441 ctaccatcaa gaaattgaaa gaaaatggca tcaagttcaa gtaatttttc ttgagccttg
    13501 catttccgag aaaaacttgc tacaatagag ccattagagg tgttttgaat cccacatttt
    13561 acagaaagtg gcggcgctga gaagtccaca aatgtgtcaa aactggttgc taatgactga
    13621 aaaaatgaaa tatttctgtc tttttatttt aaagactaaa gatgcgggct tggcccgaaa
    13681 ttgggtggta ccgcggataa acacattcgt ccctgtcatg tagatggcag ggcttttctt
    13741 ttgtgtctta gtcaaaggag gttgttataa aacaatcatt taaaactaat aaactatatt
    13801 atggttttcc tgtttttatt ttaggatatc aagattagaa ttttggctat aacatcacga
    13861 cctgtagttc ctcttatagt ctaggagatt gggttgtgat tggagtcgtt gcgagagaga
    13921 atgccgcaga gcagatcaaa cagtatcaaa aatttactgt gaatatttct gatgaaactt
    13981 ctatgcttgc gatggagcag gctggtttta tcagtcatca ggagaaattg gaacgtttgg
    14041 gagtgcatta tgaaatttct gaacgaactc agatttctat tttagacgcc tgtccacttg
    14101 ttttagattg tcgggtagat aggattgttg aggaagacgg tatttgccac atctttgcca
    14161 agattcttga gcgacttgtt gccccagaat tcctggatga aaagggacat tttaaaaatc
    14221 aactgtttgc cccaacctat ttcatgggag atggatatca gcgcgtttat cgctatctgg
    14281 acaagcgtgt agatatgaag ggcagtttca tcaaaaaagc gaggaagaag gatggcaaga
    14341 actgagctgt cagataaaat cgaaacagaa cgtctcgttt tacgagtccg tactgtggcg
    14401 gatgctgagg atatccatgc ctacgctagt ttgccagagg tcgcctatcc agcaggtttt
    14461 cctccagtca agaccttgga agatgagatt tattatctgg agcacattct tccggagcgt
    14521 aatcaaaagg aaaatctccc agcaggctac gggattgtcg tcaaaggaac ggataagatc
    14581 gctggctctg tcgatttcaa ccatcgccat gaagatgatg tgctggaaat cggctatacc
    14641 ttacccccag actattgggg gcgaggttat gtgccagaag ctgcgcgtgc cttgattgac
    14701 ttagccttta aagatttggg tcttcacaag attgaactaa cttgctttgg atataacctt
    14761 caaagtcaac gagtcgcgga aaagcttggc tttaccctcg aagctcgcat ccgagaccga
    14821 aaggatgttc aaggaaaccg ctgtgacagt ctgatatatg gcttgctgaa gagcgagtgg
    14881 gaggtgattt gatgcatctt ttcatcattg gtgctccagc atcaggaaaa atgaccattg
    14941 gtcaagaatt atctcgactg acggatgcta ccctatttta taaccatcaa gccattgatt
    15001 ttgcactaga aatctatcag gactatacag aggaaatgtg ggaatttgtt cgtggaatca
    15061 ctttttcatt ccttggagca agtgcaagaa atcagcgatc agtaatttta acagatgtaa
    15121 ttgatttttc aaatcagtat catctgatat atttaaagca aattcagaat ttgttggatg
    15181 attatcatca agagattctt tttgttgagt tggaaacaag tcttgaagag tgcatacgtc
    15241 gaaatcgaac ggagaatcga ttaaagcaca aacccttaaa acgacatatt gaggtatctg
    15301 aaagagaaat tttagagacc gctgaaacac ttcaattaaa ttcccaatat caaccgaatg
    15361 agttgcacca ctactttaaa ataaataata cgaatttgtc tgcagaagaa gctgctaagc
    15421 agattcaaaa taaaataaac aaaatagaga aaggacacac acatgtctaa agaactttca
    15481 tctaaataca atccagccga ggttgaggct ggtcgttacc aaaaatggct tgatgctgat
    15541 gttttcaagc cttcaggcga tcaaaaggct aagccttatt caatcgttat tccaccacca
    15601 aacgttacag gtaaacttca ccttggtcac gcttgggata caactttgca agatattatc
    15661 atccgtcaaa aacgcatgca aggttttgat accctttggc ttcctgggat ggaccacgca
    15721 gggattgcca ctcaggctaa ggtagaggag cgcttgcgtg gtgagggcat ttcccgctat
    15781 gaccttggtc gtgagtcttt cttgacgaaa gtctgggaat ggaaagacga atatgccact
    15841 actatcaagg aacaatgggg caagatgggg ctctctgtag actattctcg tgagcgtttc
    15901 actcttgacg aaggtttgtc aaaagctgtt cgtaaggtct ttgtggacct ttacaagaaa
    15961 ggctggatct accgtggtga gtttatcatc aactgggacc cagcagctcg cacagccctt
    16021 tctgatattg aggtgattca caaggatgtg gaaggtgcct tctaccacat gaattacatg
    16081 ctggaagatg gttcacgcgt ccttgaagtt gctacaactc gtcctgagac catgtttggg
    16141 gacgttgcgg ttgcggtcaa cccagaagac ccgcgctaca aggacttgat tggtaaaaat
    16201 gtcatccttc caatcgctaa taaactcatc ccaatcgttg gagatgagca cgcagatcct
    16261 gagtttggta ctggtgtcgt gaaaatcaca cctgcccacg atccaaatga cttcttggtt
    16321 ggccaacgtc ataacttgcc acaagtcaac gtcatgaacg acgacggaac catgaatgac
    16381 ttggcctttg aattttcagg catggaccgt tttgaagctc gtaaggcagt cgttgctaag
    16441 ttggaagaaa tcggtgccct cgtcaaaatc gaaaaacgtg tccacagtgt tggtcactca
    16501 gagcgtacag gtgttgtggt tgaacctcgc ttgtctactc aatggttcgt caagatggac
    16561 caattggcta agaacgccat tgccaaccaa gacacagagg acaaggtcga attctaccca
    16621 cctcgtttca acgatacctt ccttcaatgg atggaaaatg tccacgactg ggttatctct
    16681 cgtcagctct ggtggggtca ccaaatccct gcctggtaca atgctgatgg tgaaatgtat
    16741 gtcggcgaag aagctccaga aggtgacgga tggactcagg acgaagacgt cttggatact
    16801 tggttcagtt ctgccctctg gccattttca accatgggct ggcctgaagt cgactcagaa
    16861 gactttaaac gttatttccc aacttcaacc ttggtaacag gttacgacat catcttcttc
    16921 tgggtgtctc gtatgatctt ccagtcattg gaattcacag gccgtcaacc attccaaaac
    16981 gtccttatcc acggtctcat tcgtgacgag caaggacgca agatgtctaa gtctctcggt
    17041 aacgggattg acccaatgga tgttatcgag aaatacggtg ccgatgccct tcgatggttc
    17101 ctttcaaacg gttctgcgcc aggacaagac gtgcgtttct cttatgagaa aatggatgct
    17161 tcatggaact ttattaacaa gatttggaac atttctcgct atatcctcat gaacaatgga
    17221 ggtttgacgc tggatgtggc gcatgacaat gtcacaaaag ttgcaacagg tgaggctggt
    17281 aatgtgacgg accgctggat tctccacaat ctcaacgaaa ccattgcaaa agttactgaa
    17341 aactttgata agttcgagtt tggtgtggct ggtcatatcc tttacaactt catttgggaa
    17401 gaatttgcca actggtatgt tgagttgacc aaggaagttc tttacagcga caatgaagac
    17461 gataaggtaa ttactcgatc tgttctcctc tatacgctgg ataaaatcct tcgtctcctt
    17521 cactcaataa tgccgttcgt gacagaagaa atctttggtc agtacgctga aggctctatc
    17581 gtgacagcag catacccaac tgtcaaccca gcctttgagg accttgctgc ccacactggt
    17641 gtggaaagtc tcaaagactt gatccgtgcc gttcgtaatg cgcgtgcgga agtaaatgta
    17701 gcaccaagca aacctatcac catccttgtt aagactagcg atagtgactt ggaagccttc
    17761 tttaacagca atgtcaacta catcaaacgc tttacaaatc cagaacactt ggaaatcgca
    17821 tcaaccatcc ctgcacctga actggctatg tcaagcgtta ttacaggagc cgaaatcttc
    17881 ttgccactgg tagacctctt gaatgtcgaa gaagaattgg cacgtctgga aaaagaactt
    17941 gccaaatggc agaaagaact cgacatggtt ggcaaaaaac tcagcaacga acgcttcgtc
    18001 gccaacgcta aaccagaagt tgtccaaaaa gaaaaagaca aacaagccga ctaccaagcc
    18061 aagtatgatg tgaccgtagc acgtattgat gagatgaaga agttggtgaa ataaacacag
    18121 aaacacggtg atgagccgtg ttttttggta taatgaaatc aatatctatt gatggagaaa
    18181 gtgatgtcca aacaccctca ttatgaattg ttaaatttaa ttggctacgg tcttgccaag
    18241 tttgacaagc tttttataaa agaatttcaa tgctctagca agtcggagtt ttatcgctat
    18301 gtggtttctc tgggaattgc tgaaacaact ggagttgtaa aaaatagaat ggatttattt
    18361 gatccttatt ttgacaataa tcgaaaaggt tggtggcaga aagctgaagt ttatcgtttt
    18421 cgtaaagatt taattgatat gatgtttgga aatgaagatg ttcatagtta tgctgaaata
    18481 gttaaaatgt tacttgccag tgaagggaag aaaacaggca taaccatcgt tgaaaaacca
    18541 atagttcgaa ctaaattcaa acgtctacag gaaacgggaa tggaggctga gaattatttt
    18601 atccttcatt ttgataaaga agaaaaattc caaggtggac agttaaccga tgcccgtctt
    18661 tatggtgatg gatatgactt tcaggtagat gtccaagagt attcttacct tgccgaagta
    18721 aaaggtatcc gaaaatctaa ggggcgtgtg cgtttaactg caaaagaatt tgaaaaagtc
    18781 aaggagtttc aatcggattt tattttatcc ttggtcacaa atctagatga tattccaaag
    18841 ttagtgttaa tcgataatcc tttaaaacat tttgagttta aaaagaatat tatcaaaaat
    18901 gaaatcattg aatatagaag cgtagaggat ttgtattagt tcccccttaa cttttccagt
    18961 tgaaggaacg agaagtcttg acaggtcaac gacttaatga actggaaatc aacggtattc
    19021 gtttgactaa gttttaagat ggcgaaatcg gtattgaatt tatcagtagt gctgattata
    19081 actcttttat tatttacatg aagtatatat atatatcata gaacctattg tgaggacttt
    19141 ttatagttta agccagtttc caaccaattt cgtgatttac tggtaatgaa gaaaaacaat
    19201 tgaaaggata tttctatgca accaacttac aacattgaca atccaaactt gtcttatgaa
    19261 gcgaagcgtg atttatggcg gataggtttt ggtctgcaga aagttgacaa tctagtgcca
    19321 tcagcgtata tggaatcttt ggctgagaaa cagtcccggg gagaactgac ttatgagcag
    19381 gtttatgagg atgcaacggc ttatcaccat actattgatg caagtacgga agaggcagac
    19441 ttggtttctc tacgtattgt agaactattg tctcgaagag gctttagctt tagtcctgcg
    19501 accttacttg ctattcataa ggagttgttt caagatatat ttgaaccctc tattccggtg
    19561 gggcaatttc gtcagaccaa tatcacaaag aatgaacctg ttttgaatgg tgaaagtgtt
    19621 gtgtactctg attactccat gattcaaatg accttagatt atgattttaa tcaggaaaaa
    19681 caagttgcat atgcgacact aactcaggcg gatgtggtta aacaaatcca gcattttatt
    19741 tcaggaatct ggcagattca tccatttcgc gaaggaaaca ctcggacagt aacggtcttt
    19801 ttgattcagt atcttcgtga gtttggtttt gatattgata atacaccatt tcagcaacat
    19861 tccaaatatt ttcgtgatgc cttggtatta gataatgcaa agattttaca gcgacgttct
    19921 gagtttttaa cagctttttt tgaaaatctc ttgctcggtg gtcaaaatga tttgtcttca
    19981 gaaaaaatgt atctagattt agacctcgat ttttcataat ccaaatactg agtaaacatt
    20041 gaattttagg caaaaatgaa gtaaatattc tcacaagaaa acgtatatca tcaaagtttt
    20101 aggtgtactg accccaaaaa gttagacaaa taatttatcc gaaggattta gttctgtact
    20161 gcacaggact aagtcctttt agttttacct taattctctt gttgttgtaa taatcaatat
    20221 agtctacaat agcttgttcc aattgcttaa gcgactgaaa cgacttctca taaccgtaaa
    20281 acatttccga tttcagaatc ccaaagaagg actccatcat accgttgtct tggctgtttc
    20341 ccttgcgtga catagatgct tgaattccct tactcttagg aaccgatgat aagaatcgtg
    20401 tcggtattgc cagccttggt cactatggag aatcgtattc tcgtagtgct tctctgtgaa
    20461 tgcctgttcc aacattgttt gtacttgttc taagttgggt gaagttgaaa gattataggc
    20521 gataatttcg ctgttaaagc catctaaaac tggtgataag taaagctttt gagtacttgc
    20581 tggaatggca aattctgtca catctgtgta gcacttttcc attgttttag agccttcaaa
    20641 ttggccttga atgagattct ctgccttctt accaacgtct cctttatttt cgtttctgtc
    20701 gcattttagc ttgtaaattg agtactttta tcaagccttg aactctttta tgatttacca
    20761 gataagcacg atttcttagt tctaaatgaa tacagcgata agcataattt cccttgtgtt
    20821 cgataaagat ggattgaatt tcagctttaa gctcttggtc cttatctg
//
LOCUS       DAVKAU010000029        20662 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVKAU010000029 DAVKAU010000000
VERSION     DAVKAU010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20662
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.029"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..162
                     /locus_tag="VWX48_001297"
     CDS             <1..162
                     /locus_tag="VWX48_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9171921.1"
                     /translation="EEFGHKLLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCCNTFYE
                     ALLSCSCFN"
     gene            complement(155..328)
                     /locus_tag="VWX48_001298"
     CDS             complement(155..328)
                     /locus_tag="VWX48_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU9171922.1"
                     /translation="MNIKKRVLGAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(487..2094)
                     /locus_tag="VWX48_001299"
     CDS             complement(487..2094)
                     /locus_tag="VWX48_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU9171923.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPMQEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2246..3730
                     /locus_tag="VWX48_001300"
     CDS             2246..3730
                     /locus_tag="VWX48_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU9171924.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYTGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKISRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3825..4307
                     /locus_tag="VWX48_001301"
     CDS             3825..4307
                     /locus_tag="VWX48_001301"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU9171925.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(4603..6708)
                     /locus_tag="VWX48_001302"
     CDS             complement(4603..6708)
                     /locus_tag="VWX48_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9171926.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTCGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQVAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(7317..8297)
                     /locus_tag="VWX48_001303"
     CDS             complement(7317..8297)
                     /locus_tag="VWX48_001303"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU9171927.1"
                     /translation="MFIFISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLFTSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKIFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(8299..10551)
                     /gene="pbpX"
                     /locus_tag="VWX48_001304"
     CDS             complement(8299..10551)
                     /gene="pbpX"
                     /locus_tag="VWX48_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU9171928.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(10555..10872)
                     /gene="ftsL"
                     /locus_tag="VWX48_001305"
     CDS             complement(10555..10872)
                     /gene="ftsL"
                     /locus_tag="VWX48_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU9171929.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(10884..11834)
                     /gene="rsmH"
                     /locus_tag="VWX48_001306"
     CDS             complement(10884..11834)
                     /gene="rsmH"
                     /locus_tag="VWX48_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU9171930.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            12000..12194
                     /locus_tag="VWX48_001307"
     CDS             12000..12194
                     /locus_tag="VWX48_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9171931.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            12210..12752
                     /locus_tag="VWX48_001308"
     CDS             12210..12752
                     /locus_tag="VWX48_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU9171932.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            12763..13005
                     /locus_tag="VWX48_001309"
     CDS             12763..13005
                     /locus_tag="VWX48_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171933.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            13016..13351
                     /locus_tag="VWX48_001310"
     CDS             13016..13351
                     /locus_tag="VWX48_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171934.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(13461..14462)
                     /locus_tag="VWX48_001311"
     CDS             complement(13461..14462)
                     /locus_tag="VWX48_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9171935.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(14522..16423)
                     /locus_tag="VWX48_001312"
     CDS             complement(14522..16423)
                     /locus_tag="VWX48_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU9171936.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(16445..16738)
                     /locus_tag="VWX48_001313"
     CDS             complement(16445..16738)
                     /locus_tag="VWX48_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9171937.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(16738..17556)
                     /locus_tag="VWX48_001314"
     CDS             complement(16738..17556)
                     /locus_tag="VWX48_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9171938.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(17543..18322)
                     /locus_tag="VWX48_001315"
     CDS             complement(17543..18322)
                     /locus_tag="VWX48_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9171939.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(18337..18828)
                     /locus_tag="VWX48_001316"
     CDS             complement(18337..18828)
                     /locus_tag="VWX48_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9171940.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKVALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(18838..20028)
                     /locus_tag="VWX48_001317"
     CDS             complement(18838..20028)
                     /locus_tag="VWX48_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU9171941.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINEDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGMTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(20040..20474)
                     /locus_tag="VWX48_001318"
     CDS             complement(20040..20474)
                     /locus_tag="VWX48_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9171942.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
BASE COUNT         6032 a         4684 c         3690 g         6256 t
ORIGIN      
        1 gaagagtttg ggcataaact tttacctctt cctccctact cacctgagta caatcctatt
       61 gagaaaacat gggctcatat caaaaagcac ctcaaaaagg tattaccaag ttgttgcaat
      121 accttttacg aggctctttt gtcctgctct tgtttcaatt gactatatta tcagcgtaat
      181 agtctaatag atagttaaat gtagttggat ttccactaaa ggttgatgag taagtttttg
      241 tatctgaacc tgattggccg caagcagcta aaagcaaagc agatgcaaaa gtcagacctg
      301 caccaaggac acgcttcttt atgttcatct tctttctcct taatagtggg aatttgtaaa
      361 gttaattgaa tttcaagaat gaaggtttat aaactttggt tataaaaaac aaaggatttc
      421 tgtcttttat acagtcctcc cttgttttta tacgatttca attttaaatt tttctgcaaa
      481 aaatatttat agtaattcca cacagaaagc atcccatgga actaagattt gtttttcaaa
      541 gacttcttga gctagggtgt tttcaatcaa gacagatttg acttttcctt ctactgtcaa
      601 gtcttgctct tcattggaca agttagccac aactaggaag cgacggtcgc catccttacg
      661 tatataagca aagaccttat cagccgtatc aagcaattca aagtcagctc gaattagcca
      721 actattctcc ttgcgaattt ggaccagttt ctgataggta tagaaaatag aatctggatt
      781 tgccagcgct tcttggacgt tgatcatctc gtaatttgga ttaactgcca accaaggttg
      841 acctgttgag aaaccagcgt ttttgctctc gtcccattgc ataggggtac gggcattgtc
      901 acgtccaata acacggatac tgtccatgat ttcttgcatc ggaacacctt tttcaagagc
      961 ctcacgcgca tagttgagag attcaatatc ttctacttga tccagtgttt caaacggata
     1021 gttggtcatc ccaatctcct caccttggta gatataagga gttcctctca taagatgaag
     1081 caagattgca aaggctttgg cagatttttc gcggtattct tggtcatttc cccagattga
     1141 gacaatacga gggaggtcat ggttgttcca gaagagggaa ttccagccgt cctcaactcc
     1201 taactctgtc tgccatttgt tgaagatttc ttttaactta gcgatattca gctctttttg
     1261 atagtgccat ttaggctgac cttcctgata ctgaagaccg atatgttcaa actggaagac
     1321 catagacaat tcttgcccct ttggatcaga gtagagtttg gcaatctctg gcgttgctcc
     1381 ccaagtctcc cctactgtca agagatcctt atctccaaag gtcgcctgat tcatttcctt
     1441 gagataggga tggagcatag gaccattatt gactaccttc tcgtcaggaa ttttgccaat
     1501 catgtcaata acatccatac ggaaaccacc aataccctta tcaatccaga agttcatcat
     1561 ctcataaatt ttctggcgaa gtttttcatt ttcccagttg agatccggct gtttcttgct
     1621 gaaaaagtgg agatagtatt gacctgactt ttcatcgtat tcccaagcag acccactaaa
     1681 gatagaatct aggtcattgg gttcatcgcg ccagatatag tagtctcgct cagggctatt
     1741 aggattttca caggcctcta caaaccaggc atgctcatcc gaggtatgat tgaccaccaa
     1801 gtccatgatg atacggatat cacgcttctt agcttctgca atcagttcat ccatgtcctc
     1861 catggttcca aaaatagccg caatcgcttg ataatcagca atatcgtagc cattatcatc
     1921 catagggctg tcataaacgg gagaaagcca aatcgctgtg attcctagct tagctagata
     1981 gtccaactta ctggtaatac ctggcaaatc accaactcca tctccattac tatccataaa
     2041 actctttgga tagacttgat agactacggc attatgccac catttttctt gcatcttctt
     2101 acctcattat tttaataatc tatagtatat gatagcactt tttaaaattt tgtgcaagcg
     2161 tttgcttaat ctttttaatt tcttttttag ctccgtagtt tcctaacttc caatttttta
     2221 ttataataga gtccagaggt aaaaaatgaa aaaacaagct tttagttctg aacaatattt
     2281 gaatttacaa cgcgaccata ttttggagcg cattaaccaa tttgacggca agctctactt
     2341 agagtttggc ggtaaaatgt tagaagattt ccacgctgct cgtgtccttc ctggttatga
     2401 acctgacaac aaaatcaagc tcttgcaaga attgaaagag caggttgagg ttgtgattgc
     2461 cattaatgct agcaacattg aacattccaa agcacgtggc gacttaggca tttcttatga
     2521 ccaagaagtt cttcgtttga ttgacaaatt caatgaatta gggatttttg ttggttccgt
     2581 tgtcattaca caatacactg gtcaacccgc tgcagatgcc ttccgcaacc aacttgagaa
     2641 aaacggaatt gattcttatc ttcattatcc aatcaaagga tatccgacgg atatggatca
     2701 catcatttcc ccagaaggca tgggcaaaaa cgactacatc aaaatcagtc gcaacttgat
     2761 tgtcgtaacc gctcctggac ccggttctgg aaaattggca acgtgtatgt ccaatatgta
     2821 ccacgaccaa atcaatggca tcaagtctgg ctacgctaaa tttgaaacct tccctgtttg
     2881 gaatcttccc cttcatcatc cagttaactt ggcttatgaa gctgccacag ctgaccttga
     2941 tgatgtcaac atgattgacc ccttccatct tcaaacctat ggagaaacca ctgtcaacta
     3001 caaccgtgat atcgaaatct tcccagtgct caagcgcatg ttggaacgta ttctcggaaa
     3061 atcaccatac gcttcaccga cagatatggg tgtcaacatg gttggtttcg ctattacaga
     3121 tgacgaggct gctgtcgaag cttctaaaca agaaatcatc cgccgttact atcaaacagt
     3181 tcttgacttc aaagctgaaa aagttggcga agctgccgtc aagaaaattg agttgctcat
     3241 gaacgacctc ggtatcacac ctgcagaccg taaggttgct gtcgttgcgc gccaaaaagc
     3301 agaagaaact ggtggaccag ccctagcctt tgaattgcca aatggggaaa tcgtcactgg
     3361 taagaactca gaactctttg gtcctacagc cgctgccttg atcaacgcca tcaaaaaatc
     3421 agctgacatc gctaaagaag taaaactaat cgagcctgaa gttgttaagc caatccaagg
     3481 tcttaaaatc gatcatctcg gtagccgcaa tccacgcctt cattcaaatg aaatcctgat
     3541 tgcacttgct atcacagcta cagaaaatcc tgatgctgcc cgcgctatgg aagaactcgg
     3601 caacctcaaa ggaagcgaag cccactcaac catcatcttg actgatgaag acaagaatgt
     3661 ccttcgtaaa ctgggtatca acgtaacctt tgacccatac taccaatacg accgcttata
     3721 tcgtaagtaa agatttcaac ctctccagcc tcggagaggt tttctctctg tctcaggagc
     3781 aacctttatg atataatgag agaagaaaac tgaaaggatt taccatgtca aaagaagtta
     3841 ttgtcgaaag ttttgaactt gaccacacca ttgtcaaagc accctatgtt cgcttgattg
     3901 gggaagaaac aggacccaaa ggagacatca tctccaatta tgatattcgc ttggtgcaac
     3961 caaacgaaga ctctatccct actgccggcc ttcacactat cgagcacctc ttagccaaac
     4021 tcatccgtac ccgcattgac ggcatgattg actgttcacc atttggttgc cgcacaggct
     4081 tccacatgat tatgtgggga cgtcacacca gtgctaaaat cgcagctgtt atcaaggatt
     4141 cgctcaagga aatcgctgaa actactactt gggaagatgt cccagggaca accatcgaat
     4201 cttgcggaaa ctacaaggac cacagcctct tctctgctaa agaatgggca aaactcatct
     4261 tggaacaagg gatttcagat gatgcctttg aacgtcatgt gatttaaaat cgagtagggg
     4321 ataatctcta gcccctctca caccaccgta cgtaccattc ggcatacggc ggttcaacta
     4381 acttttaacg catgtcgttc aaggtaataa tccaaacacg aaaccagtcc gcgtttttca
     4441 aggactggtt ttgatatagc acgtttaagt atcgacttct gagctactat agtatattga
     4501 aactagaata gtacacttct actatacgac atgcccgtcg tacctcaaaa ggaaccagtt
     4561 tttttcagct ggctccttct tttttatcct caaaattcta tcttaggctt tctcacgaat
     4621 aaccaaaacg ccatcttcca tatctgcttc cagatgttta gcatctaaat gatctaagtg
     4681 gaagtctgtc accttatcac gaatttcttg ttcaaccacg cgacggagag gacgaacccc
     4741 catgacttcg tcgtaacctt cttctgtgat ataatcttta gccacttgac tgactaccaa
     4801 gtcaatgtct ttcttagcca aggtttggtt aacttcagcc aacatcaaat ctacaatctt
     4861 agaaaggtct tccttagtca agtgtgaaaa ctcgatgact gcattaaagc ggttgaggaa
     4921 ttctggacgg aagaagggtt tcaaacggtc catcaattct ggtttatccg catcttctgt
     4981 caagttggct tcatagccaa atccagcatt tgaggtcgca ataatgacag tgttcttgaa
     5041 gtttactgta tttccttgac catctgtcaa acgaccatca tctagaactt ggaggagaag
     5101 ggtaataact tgaggatcag ccttttcaat ttcatccaag agaatgatag agtatggatt
     5161 gcgacgaaca cgttctgtta aggtattgct attgtcatca taacccacat agcctgctgt
     5221 tgtaccaatt agcttagaaa cagctgtgcg gtcactgtat tcagacatat ccaaacggat
     5281 aatcgcatcc tgggttccaa acatatcgag tgccaattgc ttagcaagct ccgtcttacc
     5341 aaccccagta gaccctacaa agaggaagct gccgattggg cgatttcctt catcaaaacc
     5401 agcacggtta cgacggatag cacgagctac agcttctacg gccttatctt gaccaatcac
     5461 cttgtcttgc aagcgatgag ccatatcttt caaacgttcg atatctgaag ctcccatttg
     5521 cgatactggg atacctgtca ttcgttccac agattcagcc acatcgttga cacttgcagt
     5581 cactttcata tcttctgtgt ggttttcgat tttcctttcc aattctgcaa tgcgtgtttt
     5641 atagtttaga gctgcttcaa aatcttctgc ttcaactgct ttttcttgct tgtctttttc
     5701 cgtttcgatt tctcgttcaa cagcatgcac atctgttact ggatgttgag ccgccaagtg
     5761 agcagccgtt acatcgacaa ggtcaatagc cttatctggc aagctacgtt gaggaatgta
     5821 ttgaacagaa taatccaccg ctgctttcaa gacttcgtct ggcaagatga cattgtggtg
     5881 ttgttgatag aggtcacgaa tgccttgaag aattttaaaa gtattctctg ctgaaggagc
     5941 attgaccttc acttcgttga aacgacgagc aagagcagca ttcttcaaga tggtgttacg
     6001 gtattcgtct tgagttgttg ccccaatcac tgtcaattct ccacgagaga gagctggctt
     6061 gagaatatcc gcaagccctt tagaaccact gtctccacaa gtgctaccag caccaagaat
     6121 ttggtgaatt tcatcaaaga agaggataat attccctgct tctttcactt cattgactaa
     6181 gttttggaca ttttcttcaa agctaccacg gtattgagta ccagcctcaa gacctgagat
     6241 atcaatagaa ataatttcct tgttcttgat agcagcagga acatctccgt tcacaatggc
     6301 ttgcgctaga ccttcgacaa ctgctgtctt accaacacct gcatctccga ccaaaacagg
     6361 attgttcttg gtgcggcgtg agaggatttc agatgtttct tgaatttcct tgtttcgtcc
     6421 gataacagga tccaacttgc cctcacgcgc ttctgctgtc aagtttcgac ctagttttgc
     6481 aaggacaccg tcttgtttca tacctgatgc ctgttgtggc atttgcacat cagtttctgc
     6541 atttcctggt aattgaccag tcgtacgata gtgagcaaat tcctcaggtg tgacttcgcg
     6601 tccattaatt aagtaacggc gattttcaga actgtatcct cgcataccac ccatcaattg
     6661 gttaaataaa tcatccatgt tattaaaatt attaaagttg ttattcatat tctttacctc
     6721 tttttgttta cttagttatg attactgata ttgactatct ttgacctttg ttttaaaaaa
     6781 tttagactag ctaaaccgct actctacgta ctatttctgg tttttctttt tcaagcagga
     6841 gtagactatc tttacttctg aagatttcta gatgaaacat aggctcacct ctttctattt
     6901 tactttaaat aagtgttcta gtaaggcttt catttacctt acgttcataa tatactacat
     6961 tagtcagaaa aggtcaatag ttttgacttt aactgaccaa tattttttta cactcttcga
     7021 aaacctcttc aaaccacatc agcttctcct tatctacaac ctcaaaaccg tgttttgagc
     7081 tgacttcgtc agttctatca accatctcaa aactgtatag taaaatgaaa taagaacagg
     7141 ataaatcgtt caggacagtc aaatcgattt ctaacaatat tttagaagta gaggtgtact
     7201 attttagttt caatatacta tgttttgagc agcctaaagt tagctttcta gtttgttctt
     7261 tgattttcat tgtgtattta aacacaaaaa caccctaaaa catcagggtg ccattcttac
     7321 atcaaatata aaattgctag ggtcaggaga cttgctagaa gcccaactcc ccaaaagaag
     7381 aagtcaacct tccactcgct ccaaggattt cctttaccag acaatccccc aagctcaaaa
     7441 tggtgatgta caggcgtcat acggaaaata cgtttaccac ctgtcagttt gaaataactg
     7501 acttgcatca taacagaagt tgtttcaaaa acatacacaa ttccgataat caagagagtc
     7561 cattcttggt ggagagccat agagatagct gccagcattc cacctaaagc caaacttccc
     7621 acatcaccca taaagatctt agcaggctta tggttaaaga tgaagaaact gagcaaacca
     7681 ccaatcatgg ccagaatcac tagaagaata tccatctgac cttgcacata ggcaataact
     7741 ccataggcag acaaactaat cacaacggaa atactagcta aaccgtcaac accgtctgtc
     7801 aagtttactg cgtttgaaaa accgactagc cagaaaagag cgaagacaat atagaaaatc
     7861 cctagatgca cttgataacc aaagacagaa agcatatcgc caccgcgctc atagaaaaga
     7921 tagaagataa ctccacctag aagctgaaga gctaattttt gcttaggatt aagcccctca
     7981 ttgattttac gaaagacctt gagaaagtca tctaaaaatc cgaccaagcc atacaagacc
     8041 aagatgaaca aaatcattcc cacattattg ctgaattggc tactaaatag ggcgaaaaag
     8101 aaagcaacca aaacagaagt aaacaagaaa accaaacctc ccattgtagg agtcccagct
     8161 tttgcctgat gctgtttgac atcctcatgc atctgctggc ctgtaatttg cgcctttcta
     8221 taaaattgga taaaggccgg aattcctact aaagttagta aaaatgtcac aattccagca
     8281 ctgatgaaaa taaacatatt agtctcctaa agttaatgta atttttttaa tgtccttgat
     8341 agctgtgtta gcacgaacat cttgcttctg cacagtagag cccgagcctt gaaattcaag
     8401 ttctatattg agccacttag caagggtctc agcagtctcc tttgtccaac catacatatc
     8461 tggaacctcc tctgctttat cagataagat aaggacttgc tgattcgggg caagattctt
     8521 cccttcttca gcagaactgt ttttaatctt cgttcctgtt cccacaacga tgggttgtac
     8581 aagattgcga cgcaattctt ctgctaaatc accaggtgaa atatccttga cactaggcat
     8641 aggataagga ctttgttgac ttacttgctc caaagcttta gctgttgttt gaagattgag
     8701 agagtctttc atagctgaag cccgctccaa gataggattg gcaaattctc ccaactgaat
     8761 acctgaataa tgttcaggtt gttggaccgt cacatacaag ataaaatcag gattttcagc
     8821 cggactcatc gatacagccg agaaaatata gtcggttaac ccgactagat aaccaccatt
     8881 tttctcgtca gcaatctgag ccgtaccaga cttgagggct acattttgcc caggaacagt
     8941 tacagttggc ttgcctgtgc tgtggttata catggttcca taaaccggat ccgtccctac
     9001 caaaaccatg ttagtccgag ttagactagc tgcatcttta gaaacaggat ttcccacaat
     9061 ttctttttga gatttccgag cagtttgatc atttggatca taaatggcac taataaattt
     9121 aggctccagc atgacaccgt cattagcaat agctgtaaag gcacgaatca tttgtgtctg
     9181 ggtcactgaa atcccttgtc caaatgagct ttgcgcaatg ttgacaatat tatccgcagg
     9241 aagctgacca gcatactcat ccgtcaaacc gaaacgggtc ggaactccaa acttaaaacg
     9301 attaagataa tcaagccagg tagcatctcc catcttttgc tcaaggaggg tcatcccaac
     9361 gttacttgag tgtgcaaaac cttgagaaaa agtcatcatt ctgccaccag tcaatccttc
     9421 attaacgtcc caatctcgaa tcgtggcatc tgcaattttt aactcactac tattaaagac
     9481 ttctcctcct ggaaaggtat tattatcaat agcagcagcc aacatcatca ctttcatagt
     9541 ggaacctggc tcatagttac tttggtaaag gatatcacgc caaacaaagt cctctgtaat
     9601 gccttctttt gtatctgcat caaaggtcgg tcgttgcgtt gttgccagaa tttcccctgt
     9661 tttagcactg accaaagtcg ctgtcatgta ctttcctttt accttctctt gaaaagcatc
     9721 catctgggtt tccataaagg actggagggg gctggaaatg gttgtataaa catccttacc
     9781 atccatcgtt cgttgggaaa cttgttctgt tccgggtaca atattaccca gacgatcctt
     9841 ttcataggta ataatgccgt ctgtccctgc aagaatactg ttcaaggaac tctccattcc
     9901 agaggttccc agcaagctct tgcttccatc ttcattttca tggagctgag ctagaccgat
     9961 aaaactagaa gcaaattgtc catttgggta actacgattg ggactggttg taaaatcaat
    10021 ccccttgacc tctgcagctt ccaattcttt tttgatagac atcatattgg cataggtaat
    10081 cccatttccc tttgctccaa aggaaacttg cttgagatta ggttgcgaga gttgctctct
    10141 tacataggat tcttccatgt ccagatactt atgaaagacc tctgcaacct tgttaaattg
    10201 tgttttttct acgtaaagaa tcttacccgt tgctgactta tagttctcat caatgaccgc
    10261 atagacatta taggaggttg catcctcagc aatcgggact ccatttcggt cataaatagt
    10321 cccacgtttg gcaggaactg tacgggtggt ttgatgaacc ttcttagctt ccttcgctaa
    10381 atctgttcca aagcgagtgc ctgtcccaat aatgaccgca aaattgacta aaaaaatggc
    10441 aaaaacaaag acagataata aactcagact ttttccaact ctgcgtctgt tttcagccgg
    10501 cgatttccga tttttggtcg cataacggat tactcttttt gtccacttca tatcttactc
    10561 cgctattcta atattttcat tgtttaattg caaatcgtgt gaattggcaa tttctttcaa
    10621 acgttctgca cgtaatagtt cattgacctc ttgcttggca tcgtccaatt cggttttctt
    10681 ttcctctatc tgcgcattga tttttgtcaa atcattctgc acttgcaaga gcttggtctg
    10741 cataaaaata atactaatgg ctacaataag agtggttaca gcaatggaaa agtaaaaagc
    10801 tttttccaca cgcgaaaacc gtttaagttg catctgtagt atttgacctg ttttttccat
    10861 tttttctgcc atctttttcc ctcttacttg tgaatttttc tggccacgcg caacttggct
    10921 gagtgcgagc ggttattggc ttctaactct tccgcacttg gcaagattgg cttacgggac
    10981 accaattcca tcttgggctt gagatcatct gggatgaaag gcaagccttt tggaacttca
    11041 actgttgaag cttccttgaa caattgcttg gtcaagcggt cttctaagga atgaaaggta
    11101 atcactgaaa ttctaccatc cagagccaac atatccatag cctgctggat ggactcatct
    11161 gccgctccca gttcatcatt gacttcaatt cgaatagcct ggaaaatctg cttagcagga
    11221 tgacccttct tcttgagttc cttggcaggt ttgaccaact tgataatctc tgctaactca
    11281 gtcgttgtct caatcggctt cacttcacgc gcttgctcaa tcttacgcgc aatctgttta
    11341 gagaatttat cctcaccgta tttgaagaaa atacgaacca aatcatgata gtcataatga
    11401 ttaaccactt cataggctgt cagactagca tcctgattca tccgcatgtc cagtggcgca
    11461 tcctttttat aagaaaaacc acgctcacgc tggtccaatt gaggactaga cactcccaag
    11521 tcataacaaa ttccatcaat ttcctgaaca ccagcttcgc gcaaacgtgc ctgtaaatga
    11581 cggaagttat ccttgataaa ggtcaccatt cccttctcaa tgtaaggtgc caagcgtttt
    11641 tgcgcattgt caatggcatt ctgatcctgg tcaaaggcat agagatggcc tttttcactt
    11701 aatttactta ataaatactc gctatggcct gctccaccca aagtcgcatc aacgtagata
    11761 ccgtcaggtt ttacgtcaag catatcaatc gtttcgtgga gtaagaccgt tacatgatga
    11821 aattcttttg tcatatctta tctattttac cacaaatccg accagcttgc acttgtcaga
    11881 caaataggac aaggagacta ctatttcttc aaaaaatatg tcaaaaatac ttgacacttt
    11941 atgtttaaaa gactataata tagtcaaata tatacgacat aaatcagaaa ggagaccaga
    12001 tgaatcgtgt gaaagaattt cgcaaggaat tgggtatttc ccagctcgaa ctcgccaagg
    12061 atatcggtgt ctcgagacag actatcaata tgattgaaaa cgacaagtac aatccaacct
    12121 tggaactctg tctcaatctc gcccgcagcc tccaaactga cctcaacagt ctcttttggg
    12181 aggaagattt ttaaaaaagg agcaaactca tgaaaaaaga aaccttcact gaaaaactga
    12241 tcaaacgcac atacggtatt tctggtcccc ttgacgaata caaacggcgt gaggccgata
    12301 gtattgggaa ccaagtcttt atcgtcctct tttatctgat gattttcgga aatcttattc
    12361 cactccttct ggcctataaa taccctcaag aagtggctct aatctatcct cctctgattt
    12421 tagtaattgc cctcatcgct gctggctatg tcacctacca aatgaaaaaa acaggcatca
    12481 cagtcattga accagatatg ctgaatgaga aagaaagcaa gcaactacac tacccaggtc
    12541 ttaaagcagg tttgttcttt ggtctatgga tgttttttat aactcctctt ctcagtatac
    12601 tcatagatga aggtcaggac tattttcatt ctcttctcac tataagaaat ggtgtatcaa
    12661 gtattctcgg ttctattttc ttcggagcga gcatacagtt cctcatctcc cgtcgcattg
    12721 caaaaactaa gaaaaatcaa gatgaggatt aggaggaaac tcatgaaaaa agaaaagaaa
    12781 cagttacgtt atcctggtct gaaagcaggt tcgatttatg gaacagtgat attttttata
    12841 attccactca ttgataccct aacaagtgaa aatccaaatt ttatcagttc tcttctaaat
    12901 acaaaacata tttttaaaac tatactggga gctttctttt tcggagtgat gatacatatt
    12961 gtcgactcac ttcgtattgc aagagctaaa aaagaccagg attaggaggt gccttatgaa
    13021 atcactagct agactactga acattcatgt ttttatcagt attttccttt tcttcgccct
    13081 tatttcagga gctgtttctc atacagtttt actactccta ctcctctttc ttcctgcgct
    13141 caataaagga cttgagaaaa tacaatcaaa acggatacct gtcctcaacg cagccctctt
    13201 ctttctcctc atatcctttc cacaactttt aaccaaccct gtccaatgga aattttcaat
    13261 attcctagtc gtaaccatca tttcaagttt ggcctacttc tataactttt atcaagtagt
    13321 taaagaagta gatcaaaaac agttgattta ggagcttgct cccataattt ctcatttcat
    13381 aggcaaataa tcccacctag aacaagctag gtgggattat tttatttctt aacagagatt
    13441 gcaagtcatt ttccttcatt ttagaaagtc gactctttcc aattcacact acaatccaag
    13501 acttgttgcc tttcttcttg attgcggcct tcaatctggt caatcaaaat ctttgtagcc
    13561 tgttgtcctt cctcaaagga gggctgaacc agcgtcgaaa cacttggaga agaaaagcaa
    13621 gtccactccg tattgtcaaa accaatcaac ccaacttgcg gcaagttata attcaactct
    13681 ttgataacgg taaagactag aggtagggcc caacagttag ggataaatac cagagttttt
    13741 tcatcgggat cgatttcttt ttgtaaaaat tctttaattt gttccaaatt cgtatgctta
    13801 tcttcaatgg ttagactggc gtgacgcata ttagcatctg ttaaagcatc cacaaaacca
    13861 cttgcccgct caatccgagt actcaaacga ctcgtatccg ctgtaatcaa gagaaaatgc
    13921 tcataacctt tttcgataca ggactgggtc atgtcataaa cggcatcata gttattggtt
    13981 ttaacccagc tagtccggtg ttcatagagc tgactatcaa aaaagaccat tttcttcttt
    14041 ttctcatcga taatacgaga atattttcgg aaattagagg tcggctgaat aataaagccg
    14101 tctactccca agagaagcat gctttcaata taccggtcct cactctcttg gctgtaatta
    14161 ctatttccta tcattacctg gtagccattc tggctggcga tatcctcaat tcccttaaca
    14221 atttggtttg agaaactgtt ggtaatatca ccgatcaaaa caccgattaa ttttgttcgt
    14281 ttggagttta agctacgcgc aacaatgctc ggtttgtaat ttgtttcatg aataactttt
    14341 tcaatctttt cacgtgtctc ttgggacatt ttttcatatt tcccgtttag gtaaaatgac
    14401 acggttgttt tcgaggtctg agccatttcc gcaatgtctt ttatggtcag tttcttctcc
    14461 aatctaaaac acctcctact aatacttatt ataacatatt cactattcaa aatgcctatt
    14521 tctagcactg caagcgaatc attctctcat ttattttatc atatactaga cattttccac
    14581 gcatttttgt tccgtcaacg aggcacaatt tttcacctac accaatatcc tcgcttaata
    14641 acagaatcag cttgtctgtt tcgtcatttt tcacttcaaa agccagagca ttttccactt
    14701 cacgatcatc tgtctggtag acagaatgac ggatgatttc aaaactctca tgcgcaatga
    14761 tggtataatc cagcatctga ttctcaaaga attggcgctt ggtgagtttg ctacttcttt
    14821 caagctcatt gtatttagga gaaatgatgg tatcttccaa atcaaaatca acttcactcc
    14881 atagtctcaa ctgattgatt ttcccatctt gataggtcac atccttgtca aggataaact
    14941 gagtcaacgc ctcatgctga ccttgacacc tgatgtcatc taccaagagc cagacatcct
    15001 ctaccaacat gaggattttt ctcttgtgaa gataaggcaa atcaggttct gctgaccaat
    15061 aagccccttc aatataatgc attccctccc tttctttatg gtgacaaaac agggagtgag
    15121 gatagtattc atattcccag gatcccgtga ttctttccgg agctttccca tctacaatgc
    15181 aggtcgaatg actccaagca ctctttaaga gataacgttc atatatctcc cgataagaat
    15241 aacgcccagc atctatgaaa ataggttggc cttgatactg taagcaaaaa ctattctcgt
    15301 cactatggct atgggcactt cctagcggac catttttgaa aaatagataa cgatgttcat
    15361 ccttaatgca gacatgtcca gagtcttcaa agatcatgga cttaggctgc caagctctct
    15421 tttcaaattc ctgcagtcgc ttgacctttt ctcgccccag gaacaagagg ctaagcaaat
    15481 cgactttaac atccagaccg ttaagaaggt cttccttgtt caaaaccaca gcagacaggc
    15541 tcaaaatttc tgtcgtttct gtagaatcgc tatcaccaaa agccaaagtt cgtccatcta
    15601 agcctgtcat catttgaata taggtcgcca tcttttccag caactcttgg taactatctt
    15661 gcaagtctgg aagcaagaga cacaaatcca gcaaggcttt ataaacctct acatgataga
    15721 gaatcgactg ttcaaactgg cttccatctc ctaaaatctg tgtctcaatt tgctgtttca
    15781 actcctctga agcaaaatgg taagcttctt ctaggtccat cttatctgca aagaaatgat
    15841 agatagcaag catcggaatt gtttgtaaaa tcccccagtt actaagggtg tacttggcgc
    15901 gatagtagct tttcataaag tcaatctgct tttctagact gaccaaaatt ttctctagtt
    15961 ctttctcctc tagcaagtca aatttcaaga ggagcaagag tagtttcaac caagtaaagg
    16021 aacgaatacc cgtatccaag gttctagtca tcaaggattg aggagaaaat tctctcacct
    16081 gctcaatcca atcaaataga aagaacttgc acttttgaat atagtcctta tctccttcta
    16141 ccacataccc tatcataaac tgcaagagat attcttgtcg attgagcata taagcccatt
    16201 ctggatcatc ttcaaatact tgatcccata ccatcggctg gatttgatgg atttttgaac
    16261 aaggctccat atcccaagga ctatcaaaca taaaacgatt gtccatcaag cgttcaaggg
    16321 aactcttgac tttctcatag tcttttgaac agtgggacaa gatataatca cgacattggt
    16381 ttccatcgat tctttcaaaa aattgtcttc tttcttcttt cattatctat taccagaaaa
    16441 agaactactt aaaaagcagt tcttttgtct ttcccattac actttccttt tctacataga
    16501 tgaccacacc ttttgcaatc tgcaaggaga ccaagtcatc tttgatagaa atgatttttc
    16561 catgaattcc agacaataac aacacttcat caccagatgt taaagaagct aaatactctt
    16621 gtcgttgctc catctgtttg cgaagcaact tttgctgacg aatagaatga aagcttgaca
    16681 gtaaaagggg actcactgcc aagacaatca ctattccata aaacaatgtt gtatccatta
    16741 agctataatc ttaagccagc ttccgataat tccgatgata actgttaaaa taacgagttt
    16801 atatgttgtc catttctttt ctttgatcaa gtagtaaact aaaagtgtaa atagggctgg
    16861 tagaagagct ggagcaacct tatcaagcat tccctgaata cttacgatac tttgtttagc
    16921 gtctgcttta acttcccctg cagcaaaggt aatcggcacc ataatcttaa cagatgtcgc
    16981 tgccaaacca gcaattacgg ttacaccgat aatattggca atacgagaaa tcgttgccat
    17041 ctgttcgctt agtttatcaa tcacagttgt tcctagtttg tatccataca aaccagttga
    17101 caatttaatc gctgttaaaa tcgtattcat cgcaaggaag aacaagattg ggccgacaac
    17161 caagccttct tgagcaaacg aagctgcgat ggttgagaac aatggagcta aacagaattg
    17221 agaaagagaa tccccaatac ctgccaatgg tcccatcaag gccatcttga tactacgtgt
    17281 ttcttttgcc ggacggccat tttccaacat tacaagatgc aagctggtaa taaaaggcag
    17341 gaagtgtggg ttggtattat agaattcaca gttttcttcc aaggcttggt agaaaccttc
    17401 ctgatcctct ccatagtgtt ttttcaaagc aggatacatc acattggcat atcccaaccc
    17461 ttgatagtta ctatagttaa atccattttg acaaaagaat gcccgcaaag acgttttaag
    17521 ataatcacgt tttgttaatt tgttagatcc agtcatcgtg tgcttcctcc tctaccacat
    17581 gatccgctgt ttttggcttg ttataaaatt caatcaaagc aaagatagta cctacaattg
    17641 caataccaat tgttgggatg tttagataag ctgcacaaac atatcccaac aagacaaagg
    17701 gaatcaactc tttcttagcc atcactgaca agatcatcgc aaaaccgata gctgggagca
    17761 ttttaccagc aactgtcaaa cctgtaagca ataccggtgg aatgtagtct acgagtttca
    17821 acaaggtatc cattgaaagg gcacccaagc aacccaaggt aaatccaata aaggcaaaca
    17881 accaaattgt tgcatttaga gtgaacttaa atttcttcaa attatggttt ttcaagtgct
    17941 tcatcgctgt ttcaggcgca ccagcacgta cagtgtaggc gaaagtttgt aagaattgaa
    18001 tcgccacagc aatcggagta gagagggcaa gagccgcttc tggactgact ttaccagcac
    18061 tagtgatagc catcaaggta ccaaagatac caggtccgat tgggtttggt ggaacagtac
    18121 ctccagcacc aacaccgaat cccatataag ccaattcacc aatagctccc attgcaagag
    18181 cagtaggcag atcacctaga ataattccga caccaaatga cagaacaata catctattgg
    18241 tgtaaattcc taacagcatt ccactaaaac agaaagctgt ccataatcca attaaaatcg
    18301 cttgaaatac attaatcgac ataacgatct cctcttttaa atatagtcca taatgttgac
    18361 ttgaacagct ccatcatttc ctgttggagt tgttttcgta ttaaatgtta cttgatgagt
    18421 ttggctcaat tccttgaggg ccaccttgtc ctcttcaccc aggaagatgg agcgtgtcac
    18481 ttgctcttta ccagtagcat tgtgaatgtt cccaatattg atttctttga tagggacacc
    18541 accttctacc aaggttaaag catccttcac atcctttaca acgataaaga tcgtttgagc
    18601 aggattagcc ttgtgaatga tatcaatcac cttttgcaaa gggaagaaac gcatggcaac
    18661 tgagtctggc acaactgttt tcatcagagt ttgttgcatc ttgtccgtgc ttacttcgtc
    18721 attggcaaca atgaccgtat tacaacctag gtattttacc caaagttgtc cttgtccatg
    18781 aatcaaccgt tcatcgatac gggtcataat aatatttggc attgtcatat ttctcctcta
    18841 ccaatatagg ttccagtctt tgtagaaacg gataagggct tctaggtaat agtagtcacc
    18901 ccagatattg ccttcatcca ctcctttacc tgaatgccat gagtacacac cgtggaggag
    18961 acttgtccca ccaggggtaa attgatcatt tgcataatgt tcgatcaagg aacgaagcat
    19021 ggcatgcata gcatgtttat aaatatcttt gtcagcatcc acctctggga gatgttttag
    19081 catttcatga atcccacaga cggcgatagc tgttgctgaa gaatctcgtg attgatcact
    19141 accatcatta aaaatcaaat cccaatagga cacatgatct tttggcagac gattcaagaa
    19201 ataattggtc atacccttaa acaagtcaaa gcaggactcg tcttttaagt gacgataagt
    19261 caaaggaata ccatagactc cccatgactg accacgtgcc cagcatgaat catcactata
    19321 cccttgtctc gttacacctt taaagggttg acctgtctca ggatcaaaat agaaggtgtg
    19381 gaaggacgaa gcgtcatcac ggattacatt attagctgaa gcatagaaat ggctttctgc
    19441 aatatcgtag tatttttgat cgcctgtttc ttgataagca aagaataaga gttggatatt
    19501 gagcaagcaa tcgataatca aacggtaatg ctctttcttg cccaagtctc cccaagcttg
    19561 aataaaacca cctttttctt gatagcgttc aatcaactta tctgcagctt tcaaggctgc
    19621 ttctctagcc tctccatctt catttatctt atattcagcc atacaagacg gtgtgtacaa
    19681 gaagccgaga tcatggtgag ccaattctac tctcttattg acacgatcca ggaaagaaag
    19741 aacattttta tgagcgatgt ttttaaatgc atcctgttga ctgtattcat aagccaacca
    19801 cagttctcct gtccagaaac cattggtcca ttccgtgtta tccatgattg gatagacatt
    19861 atcaaaggta gctggtgtcg ggaaatcttc cttgaaatag tcaaggttga gttctaactg
    19921 ccgaataacc ttatcgattg cctggccgac ttcttctttc gtcagaagtg gtacttctaa
    19981 gaagcgctca ggcgatttta ttttttcaat cgtaaccttt tttatcattc ttttaccctt
    20041 taaatacccg attcgaaatc ttcttcctct tcctctgcat ccgttgaaaa caattcttta
    20101 ccatttacga ctccgccctg ggccgccact actgatttat taacaacttc atcaaagcta
    20161 tgagccattc tagcaaagac tgcttccatt aacatggcta agttcaaacc cgagagaaca
    20221 ttcattgttt tggctggatt ttctcccatt atggtagaag aaaccttgaa tggcgatcct
    20281 cccaagagat cacttaggat taaaacttct tcttcatttg aaattgcaag taagattttt
    20341 tgcttgagtt catctgctga cattccttcc acaaagtcaa tcgcctccac attttcttga
    20401 ttgcctgcaa tcaattgtaa agaactataa atccctgtag caaaatgtcc atgccctaca
    20461 agtacaattt tcatcttttc tcctttcttg tttaggttta ccggtttact ttatattccc
    20521 cattgtaatc ctttattttt atcttgtcaa tagttttttt aaaaaaatat tagcgctttc
    20581 attatctttt taaccatttt aatagacaga aatttcaaaa tcttccgttt ttttaggaaa
    20641 acaaatcttt ttataaataa aa
//
LOCUS       DAVKAU010000030        20342 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVKAU010000030 DAVKAU010000000
VERSION     DAVKAU010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20342
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.030"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(104..253)
                     /locus_tag="VWX48_001319"
                     /pseudo
     CDS             complement(104..253)
                     /locus_tag="VWX48_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(407..2038)
                     /gene="rlmD"
                     /locus_tag="VWX48_001320"
     CDS             complement(407..2038)
                     /gene="rlmD"
                     /locus_tag="VWX48_001320"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9171943.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2112..3086)
                     /locus_tag="VWX48_001321"
     CDS             complement(2112..3086)
                     /locus_tag="VWX48_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU9171944.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3160..3774)
                     /gene="pmp23"
                     /locus_tag="VWX48_001322"
     CDS             complement(3160..3774)
                     /gene="pmp23"
                     /locus_tag="VWX48_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU9171945.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3774..4748)
                     /locus_tag="VWX48_001323"
     CDS             complement(3774..4748)
                     /locus_tag="VWX48_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU9171946.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLAYKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4756..6012)
                     /locus_tag="VWX48_001324"
     CDS             complement(4756..6012)
                     /locus_tag="VWX48_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU9171947.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(6074..6505)
                     /locus_tag="VWX48_001325"
     CDS             complement(6074..6505)
                     /locus_tag="VWX48_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171948.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6507..7106)
                     /locus_tag="VWX48_001326"
     CDS             complement(6507..7106)
                     /locus_tag="VWX48_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU9171949.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7093..7932)
                     /gene="prmC"
                     /locus_tag="VWX48_001327"
     CDS             complement(7093..7932)
                     /gene="prmC"
                     /locus_tag="VWX48_001327"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU9171950.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLANENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(7932..9011)
                     /gene="prfA"
                     /locus_tag="VWX48_001328"
     CDS             complement(7932..9011)
                     /gene="prfA"
                     /locus_tag="VWX48_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU9171951.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9008..9598)
                     /locus_tag="VWX48_001329"
     CDS             complement(9008..9598)
                     /locus_tag="VWX48_001329"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU9171952.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPCCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            9721..9903
                     /locus_tag="VWX48_001330"
     CDS             9721..9903
                     /locus_tag="VWX48_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU9171953.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10040..11413
                     /gene="mnmE"
                     /locus_tag="VWX48_001331"
     CDS             10040..11413
                     /gene="mnmE"
                     /locus_tag="VWX48_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU9171954.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11460..12395)
                     /gene="dapA"
                     /locus_tag="VWX48_001332"
     CDS             complement(11460..12395)
                     /gene="dapA"
                     /locus_tag="VWX48_001332"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU9171955.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDVKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12451..13527)
                     /locus_tag="VWX48_001333"
     CDS             complement(12451..13527)
                     /locus_tag="VWX48_001333"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU9171956.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDSEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(13869..13941)
                     /locus_tag="VWX48_001334"
     tRNA            complement(13869..13941)
                     /locus_tag="VWX48_001334"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13906..13908),aa:Thr,seq:ggt)
     gene            complement(14041..14550)
                     /locus_tag="VWX48_001335"
     CDS             complement(14041..14550)
                     /locus_tag="VWX48_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU9171957.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14548..14644)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            14673..15104
                     /locus_tag="VWX48_001336"
     CDS             14673..15104
                     /locus_tag="VWX48_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU9171958.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15186..15563
                     /gene="mscL"
                     /locus_tag="VWX48_001337"
     CDS             15186..15563
                     /gene="mscL"
                     /locus_tag="VWX48_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU9171959.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15605..16699)
                     /gene="hemH"
                     /locus_tag="VWX48_001338"
     CDS             complement(15605..16699)
                     /gene="hemH"
                     /locus_tag="VWX48_001338"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU9171960.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            16853..18076
                     /gene="pepT"
                     /locus_tag="VWX48_001339"
     CDS             16853..18076
                     /gene="pepT"
                     /locus_tag="VWX48_001339"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU9171961.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18112..18444)
                     /locus_tag="VWX48_001340"
     CDS             complement(18112..18444)
                     /locus_tag="VWX48_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171962.1"
                     /translation="MDALLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSP
                     ARNAEANGDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTT
                     GNQEKPVE"
     gene            complement(18449..18742)
                     /locus_tag="VWX48_001341"
     CDS             complement(18449..18742)
                     /locus_tag="VWX48_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171963.1"
                     /translation="MSKANQLLERIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHFYLESNNGSDADF"
     gene            18707..18928
                     /locus_tag="VWX48_001342"
     CDS             18707..18928
                     /locus_tag="VWX48_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171964.1"
                     /translation="MDSFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19065..19274)
                     /locus_tag="VWX48_001343"
                     /pseudo
     CDS             complement(19065..19274)
                     /locus_tag="VWX48_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad protein"
     gene            complement(19395..19537)
                     /locus_tag="VWX48_001344"
                     /pseudo
     CDS             complement(19395..19537)
                     /locus_tag="VWX48_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262445.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(19571..19711)
                     /locus_tag="VWX48_001345"
     CDS             complement(19571..19711)
                     /locus_tag="VWX48_001345"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9171965.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(19755..20315)
                     /locus_tag="VWX48_001346"
                     /pseudo
     CDS             complement(19755..20315)
                     /locus_tag="VWX48_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         5873 a         4272 c         3836 g         6361 t
ORIGIN      
        1 cataccaact atttattttt tgagttttaa actttggtag aagtcttgaa ctccttatat
       61 ttacataact atttgcctct ataactgtta tgacacgaaa ccaacaagca agttcaagca
      121 cctccatatc tttattcaaa tgaggactaa gatattcaca aactttatca taaacctctt
      181 tatctttttt cataaaaggg gcatacaact tagcaaattt atcctaaaat tttttgttgc
      241 ctttatcaat catttcaacg ctcctttaaa tataaaaatg atcctatcaa tctttatatt
      301 gagcctattt tctaattgat accttgcaag aaaggaataa tagctgttcc tataccaagt
      361 aggaatgtaa taaatgcaga aagtcatata ctgtcattct tttctattaa atcattttga
      421 agtgtctcaa agcatccatg atggcttctt ctttttcagg tgtacactgt ggaataattt
      481 gtttatcctt tttagacttg ttgtaatgtt ctcgtaattc tattccacat ttctttttta
      541 tctgtgcaat atataatgtc gaaactttta attcaaattt attccaaaca tattctttga
      601 tttgagcata tgttgctttg ctctccgcac ttgtcaaatc catctcatcc agctcaattt
      661 caacacttat gtgcttatcg acatcgagtt tggacaaaag tgctaccgtc tcgacgtgat
      721 gcgtttgagg aaatagatcc accggctgga ctttcttcaa ttcatatccc aactcttggt
      781 atagtttaat atcacgcgcc atggttgcga cattgcagga gatataggcg atgcgatcgg
      841 ctcctgtttg ggcgcttgct ttgataaagc tttctgtcaa gcccttgcgt ggaggatcaa
      901 ccaagataac ggttggttga atcccatctt taagccaatt cttcatagca ttttcagctg
      961 tgtcacagac atagtgggcg tttgaaatat tgttcagctg agcatttttt ttactattct
     1021 caaccgcttc tggaatcagt tcaacaccgt agacttcttt gacatgcttg gcgactgata
     1081 aaccaatggt tccaatacca gaataagcat caataaccac atcatctttt tttaactctg
     1141 caaagtcaat ggctgtttga tagagtttct ccgccatttc agtattgact tggtaaaagg
     1201 ctgggccagc gatttggaag tcatttccca acatctggtc cgtaatatag tcttgaccat
     1261 aaagagtgcg ccactcctta ccaaaaatcg cattggtatt ctggtcgttg atattttgca
     1321 tgacagacac aatctctggg aactgcttga taacttgttc aatcaattgg tcaacacgaa
     1381 aaacttttgg acgagttgtc accaaaacga ccatgatttg tcctgaatag tgaccacgac
     1441 gcaccacaag attccgaatc aatccagact gttccttttc gtcataaggt tttaaatcaa
     1501 aacgacggag caggtctcga agagctacta cgacttggtc aatgacagga tcctggataa
     1561 agaaatcttc aaggggcatg aggttgtgcg aattcttacg gaaaaatcct gtttccaaga
     1621 caccattcac tcgacgaacg ggcacctgcg ccttattgcg atacttgact ggatgttcca
     1681 taccaagcgt ttcagcaact tctacatctg caattccagc aatcttgtag agactgtcct
     1741 tgacttgctt ggttttaaac ttgagctgtt ctggataaga aaggtgtcct aaatccgcga
     1801 ttcctgaacg caggtaagcc aaatctagat cttgattacg gtgtggtgac tggacaaggt
     1861 atttttcaac ttttccaaag ccaatctttt tattgacctt gaggacacgc atgagaattt
     1921 tttcactcgg taaagcattc tctacaaaaa agaccaaacc atctaccttg gcaactcctg
     1981 ccccttcatg ggtcaaatca acaatttcaa cttctacaat atcatttttc tttaacattc
     2041 ttttctcttt ctattggccg acaaaaaaga cggcaacgtt acggttacca tccattatac
     2101 catgaaattt cttaagaacc aaaactcttg aagaagttga caagggcttg ccagagggag
     2161 cttaagaagt taccaccgtc ctctagcgcc ttatccgcat caaagttaag gttgatattt
     2221 ttaaaactgt cgccagcttg tgatacgatg ctttgtttaa ggtcatttaa ggttttagtg
     2281 aaatctgcat tgctgaggat atcactcttt gagagattca aggcaaaatt gatgatgata
     2341 ttgatctggt ttcctgttat gacctgatca agtttgtaat tttttaaggt atcttcaaca
     2401 atcttgcgga tatcttcttc tgtcagattt cccttgcttt ctttagcttt ggcgagtcct
     2461 gacttgatat cagctagggc aacgtttaat ttattagcat catagcctga tttgtccttg
     2521 ttttcagcat tgatatctga caaagccttt agctcttctt gagccaaatc tttattggct
     2581 tgcggcacct tggctccatt agcttctagc gaatagtaga tcccagccaa agcactctca
     2641 cctgtaactg gaatgggtgc tgctacagtg attttggcgt gttccacacc caaagttacg
     2701 gctgcatttc ggtacatatc ctgagttacc ttagtgatgt tttcaggtgt ttcaatcttg
     2761 acctcaagtg gcgatttgtc acctagcttt tgaatcttgg ctgatgaata caactgtaag
     2821 ctagagtcat tggccacatt catgatttta gaataaacat caggtgtcat ggtcttgagt
     2881 tctttggtat ctgttgaggc attgtagccc agttttttaa gagtttgatt tttttggtct
     2941 tcagataggg aagaacctag gacatattca ggttggacat aggtttcatc gataactttt
     3001 tgaacatctg ttgctgcatg gacgctattc atagctgtta ctgcccacaa gatcgcagcg
     3061 ctagtcagaa agagtttctt tctcataggg aatttcctcc tttacttctt tagagtaata
     3121 tatctatctt aaagaaaact tataacaaaa acacctggtc tagccagatg ttgaaaagag
     3181 agtgaaacat ttgatgatgt aaaggttaag tcgtacctgt ctagaataat aatagtttcc
     3241 tccatttaca tagagttcag caccgtgaaa aatggaaatg gggtgaatat aactataagt
     3301 ctttccagtc ctattaccaa gcaagggggc aacagtctca cgagagtact gtttggctag
     3361 agccaaggta ttttccttgc cattttgggc gataaaatcg atataggcag gtccaaaatt
     3421 ataggcttga acagctgtcc agatatctac acccttcttc tgcgccagat agagattgcc
     3481 tgtcagagtt tgaatgcctt gccgaatgct agaggcatta tcattgatgg tgttggtgga
     3541 accacttgca gactcactag actgcataac atcgccttct tttccttttg tttcagtata
     3601 aatcatagca agcacaagct cttcgtttgc tggggtgtct ttttcactca atatttctcg
     3661 caccatgggt tgataggtca tgacttgttt gacatcttga tgaacgcggt aagctttata
     3721 gccagcaaaa aggaagactg ctagtacaag cactcttcga attcgtttaa acattattta
     3781 ctttggatat cctcgatatt tttgattaag atagagtagg ttccattttc gttttggata
     3841 aactcaacag actcggcgtc ttgatagacg ttattgggaa cgatgagctc aattccattt
     3901 gataaggaga gtttttggtt ttcaaatttc tttaattggc gactggcatc aatttcatca
     3961 aattgaacag gttctggtac ggcttctttg acttggtcaa taaagctcaa acgagccgtc
     4021 agattgttgt caaaaaggtc attagccaat ttctcaggtg acaattcatt gctttcttct
     4081 aggttgttga aaatagctga tttgaccttg gattgaaatt gaaaatcatc tgtgttaaaa
     4141 gattcagcaa ttctctgggc tgttttttcc agttccttga tagatttttt aggagaaatc
     4201 ttaggagcga cagcaagaag attatctgaa aaatagttca aaaaagtccc gttgtacttg
     4261 attcgttttt caatcaggtg atacttgcga ctctgaagat tgaccaccaa ggcctcgtca
     4321 gcacccgttc caaatccagg caggttattc tgagtcagct tgattggatt atcaacttct
     4381 cctccgaggt gggtcaaggt ctcccgcagg gcaattcgca agaaagcgaa atgttctaca
     4441 ccttctttag aaaattgaac aaaaatcaag tcattggtct tgagattttc agaaatgcta
     4501 aactcctctt tccagagatt agccagcgtt actgatgtct ccaacaaatc gtctgtaata
     4561 tgattgaaga agggattttc ttcttcgaaa atcccagtct tggcttcatc tgaatacaca
     4621 tgttcaattt ttttacgtag gtattcttcg atttttggag taatattgag aaacttatat
     4681 gctaagaaca gctcggtatc atccggactg aactggtgaa taatggcttt cttaatataa
     4741 atgtccataa aagttttagt cctcgtataa tgggaaggca tctgtcaatt ctttgactgc
     4801 acttctcact tcttctaata cagcctcatt ttctgaattc ttaagggttt taatgatgag
     4861 ttcagccact ttgcgacttt cttcttcacc aaatccacgt gcagtaatag ctgctgctcc
     4921 gatacgaatc ccacttgtct tgaatggcga caaggtttcg taagggattg aatttttatt
     4981 tagggtaata ttgacttcat ccagcaagtt ttgagcaact tttccgtttt ctacaacctt
     5041 agtcacatca acaaggaaga gatggttttc agttccacct gaaataatac ggaaatcagg
     5101 gtcttgcaag aagacatctg ccatagcctt gctgttctta attacattgg cagcatattc
     5161 cttgaaggct ggatccaaaa cttctttgaa ggaaactgcc ttagccgcca caacatgctc
     5221 taaaggaccg ccctgaatac ctgggaaaat agctgaattg atttttttag caagttcttc
     5281 gtcattggtc aaaatcaaac caccacgagg tccacgaagg gttttgtggg tcgttgttgt
     5341 tgtgatatga gcgtatggaa ctgggcttgg atgaaggcca gccgcaacca aaccagcgat
     5401 atgggccatg tccaccatga gcttcgcacc gacagcatct gcgatttcac ggaattttga
     5461 aaaatcgata atttgagaat atgctgaagc accagctaca atcagttttg gttttacttc
     5521 ttgggcttgt ttcaagatag catcaaagtc taagagttcc gtttcaggat caacactata
     5581 agaaacaaag ttgtaggttt gaccagagaa gctaacagga gccccatgag tcaaatgacc
     5641 acctgatgcc aaatccattc ccataaccgt atcacctggc tcaatcaagg acatgtaagc
     5701 cgcacagtta gcttggcttc ctgaatgtgg ttggacattg gcaaatttag caccgaaaat
     5761 ttcttttgcg cgttcaatag caagagtctc tacaacgtct actacatcag ttccaccata
     5821 ataacggcgt cctgggtaac cctcggcata tttatttgtc aagatagacc cttgagctgc
     5881 cataacagcc ttggaaacta cgttttccga agcaattaac tcgatattat tttgttggcg
     5941 ttcttcttct ttggcaatag cattccagag atcagcatca tatgctttaa aatcatcttt
     6001 gtcaaaaatc ataggtcttc tcctttattg tgtgactagt ccattagttt gattttacaa
     6061 taagaaaatc aaactaaaag atgcgaataa accgtttctg cattttatca caagtatagc
     6121 caactttttc ataaaatgca tgagcaccca gacgatgatt ggcagaattt aagcggataa
     6181 acccataacc acatcttttg gcttcttgtt ccaacccttg tagtaaactt ttaccgatac
     6241 cttgaccttg cgcttgaggt gaaactgcta aagctaagat attaaatcct gctttggaat
     6301 agagtgattc gtaaacttca gcgtggacat atccaagtaa gacatgatta gctgcatcct
     6361 catagccaag taggaaatga tgggaatcct gagacagtct agctagttgg ctagccgttt
     6421 cctctggact aaaagtataa cccaaagcct cttggttgat gtcacatatc gctttcacat
     6481 ctgtttcttg caaatctctt agcatttcaa gcctcctcaa aagaaatctc tggcaaccga
     6541 gcaagaatat cttctcgttt aattgcgcct tggcgtaaga ttttcacctt gtctccagac
     6601 aaatccacaa tagttgaatc ctgtccagtt agaaaagcat cgtcttccag acccagaacc
     6661 tcttggtcaa aatccttcag aatttgttca aaggttacac cacttgcctg acctgagata
     6721 ttggcagacg gcccaatcaa gggacctgtc tctcgaatta aatccagtgt gatagggtga
     6781 ctgggcatcc gaaatccaat agttgcaagg tcagaattta cccaataggg aactcggtca
     6841 ttggcttcga gaataatggt caagggacct ggcaaaaagg tctctacaag tttttgtaga
     6901 taagctggct gattcttaga aaagtgcaag atatcctcta aagaggcaac attgagattg
     6961 agcgccttgt ctctaggacg acgtttgagc tggtaaacat ggtcaactgc tttttcgtct
     7021 aaggccttgg caaaaagacc ataaaccgtc tctgtaggca gaatgacagc tccaccattt
     7081 tccaactctt gtctaatcct gtccatcatc aaccacgacc atcctatctt gaccaaattg
     7141 gtccttgagt gttcgaactt ttttttcagg aagatgtttt ctaaaaagtt cgggaacact
     7201 ttgaccttgc ttgtatccaa tttcaaggta aatcttacca ccatctttga gatagtcttt
     7261 tgcatcttcc gcaattctac ggtaaatagc taggccatcc tcgtctgcaa agagagctag
     7321 atgaggctcc gaatacaaga cattcaagcc tacctctgac tcatcttcac gagagatata
     7381 gggtggattg gaaacaatta tatcatattt ttcagaaatt tctgtaaaac agtcagattt
     7441 tttaaaaaat atttgaagat tttgattttt agcattttcg ttagctaaat ctaaagcctc
     7501 ttgagaaaca tctgctgctg tcactgacca atctggtcta ttttttgcta gagcgagagc
     7561 aatagctcca ctacctgttc caatatccag aactgaaaga ttcgtctcaa gattttcagt
     7621 tagaataagc tccactaact cctctgtttc tggacgagga atcaaaaccc gttcatccac
     7681 ctttaaatgc attccataaa aatctgcctg tccaatgatg tactgagctg gcttgtgagc
     7741 tgctagttgc tggtaaatat cttctacaaa ttgtttttct tcctctgttg tcacctcctg
     7801 ctggagggca aaaataaagt ctgtaaaaga tagatttttc agactacgat agacaaaaga
     7861 gaggctttcc gcttcctctc cttgtcttat caactcttct tcaaaatttg aaaataattg
     7921 agctaatttc attatttgtt taattcttct agtttttgtg tttggtcata aagcaccaag
     7981 gcatccacaa cttcgtccaa tttaccagac aaaatcgtat ctagtttttg gagggtcaag
     8041 ccgatacggt ggtctgtgac acggttttgt gggaagttat aagttcggat ccgttctgaa
     8101 cggtcaccag taccgattgt cgacttacgc tcagcgtctt gttcatcctg agcaatctga
     8161 gcaaagtggt cagcgacgcg tgcacggata atcttcatag ccttctcgcg gttcttctgc
     8221 tgggtacgtt cttcctgcat ctcaaccttg atattggttg gcaagtgaac gatacgaacg
     8281 gcagtcgcaa ccttattgac gttctgtcca ccagcaccag aggcgtgata gatgtcgaca
     8341 cgaaggtctt ttggatcaat gtcgtattca acctcttcaa cttctggcat aacaagaact
     8401 gtcgctgtcg aagtatgaac acggccttgg ctttctgtca caggaacacg ttgcacacgg
     8461 tgggcacctg attcatactt aagcttagag tatacagact gacctgaaac catagcaacc
     8521 acttctttaa aaccaccgac accattcata gaggcttcca tgacttcaaa gcgccaacct
     8581 tgggcttccg catacttttg gtacatagtt agcaaatctc cagcgaaaag tgccgcttcg
     8641 tctccaccag ctgctccacg gatttcaagg atgatattct tgtcatcgtt tggatccttt
     8701 ggaaggagca aaattttcag tttttcttca tattcttctt tttcagcctt ggcatctttg
     8761 agttcttgct tggccaattc ttccaagtcc gcatctccgc ctgattcctt aatcatctct
     8821 tcggcatcga cgatattttg aaggacttgt ttatactcac ggtaggctat tacggtgtca
     8881 cgatttgaag cttcttcttt tgaaagctcc ataaaacgct tggtgtctga aacgacatca
     8941 gggtcactca gcaattctcc tagttcttca taacggtctt ctacagcttg tagttgatca
     9001 tagatgttca tttttcttca ttctccttat tgatttcagg ggcaaaataa tgtttacggc
     9061 aaaccgagat ataggtttca ttaccaccaa tctggatctg ttctccatcg taaacgggca
     9121 gtccatcctg tgttcgcaac accatggtcg cctttttctt gcaatactga cagatggtct
     9181 tgatttcgtc aatcttgtcc gctaaaagca agagatattt ggaaccttcg aacaattcat
     9241 tgcgaaagtc atttttcaag ccaaaagcca tgacgggtat gtctaactcg tccacaacac
     9301 gagctaggtc gtaaacatgg tggcgtttaa gaaactgggc ttcatcgacc aaaacacagc
     9361 aaggtttttc tggtaggtct cggatatagc caaagatatc cgttgtttcc tcaatcgcaa
     9421 gggcagggcg tttcatgcca attcgactcg acacatagcc aacaccgtca cgcgtatcca
     9481 gagccgaggt cataatgaca acaccttttc cttgctcctc gtagttatag gccactttga
     9541 gaatctcaat cgttttacca gagttcatgg tcccataacg atagtacaac tgtgccatgt
     9601 ttcttgcttc acgtccattt ctaaattttt gctacattct agtatatcat aattttctta
     9661 agctttaaac ggcaaaatgt ggtaaaatgg aagaaatcaa aactagtgga ggaagctatt
     9721 atgccatttg tacgcatcga tttatttgaa ggacgcacgc tcgagcaaaa gaaagctctt
     9781 gctaaggaag taacggaagc agttgtccgc aacactggag cccctcaatc tgctgtccat
     9841 gtcatcatca acgacatgcc agaaggaact tacttcccac aaggggaaat gcgtactaaa
     9901 taagctagct taagcagaat tgcttaggct ttttcaatct ccaagtagca ttcattgaag
     9961 aaatatccta aatttgttac aatttgaaaa gaaacttgga gaatttccaa gaaaagagct
    10021 attaattaaa ggaaacatta tgattacacg tgaatttgat accatcgctg ctatctctac
    10081 tccactaggt gaaggagcta ttggtattgt ccgcctgagc ggaacagaca gttttgctat
    10141 tgcgcaaaag atttttaaag gaaaagactt gaacaaggtt gccagccaca ctctcaacta
    10201 cggtcacatt attgatcctc tgactggtaa agtcatggac gaggttatgg ttggggctat
    10261 gaagtctcca aagaccttca ctcgtgagga tattatcgag attaacaccc acggtgggat
    10321 tgcggtgacc aatgaaattc tccagctagc tattcgtgaa ggggctcggt tggcagaacc
    10381 tggtgaattt accaaacgtg cttttttaaa cggtcgcgta gacttgacac aggcagaggc
    10441 tgtgatggat atcatccgtg ccaagactga caaggccatg aacattgcgg tcaaacaatt
    10501 agacggctcc ctttctgacc tcattaacaa tacccgtcaa gaaatcctca atacacttgc
    10561 ccaagttgag gtcaatatcg actatcctga atatgatgat gttgaggaag ctactactgc
    10621 cgttgtccgt gagaagacta tggagtttga gcaattgcta accaagctcc ttaggacagc
    10681 acgtcgtggt aaaatccttc gtgaaggaat ttcaacggct atcattggac gtcccaacgt
    10741 tgggaaatca agccttctca acaacctctt gcgtgaggac aaggctatcg taaccgatat
    10801 cgctgggaca acacgagatg tcatcgaaga gtacgtcaac atcaatggtg ttcctctaaa
    10861 attgattgac acagctggta ttcgtgaaac ggatgatatc gttgaacaaa tcggtgttga
    10921 gcgttcgaaa aaagccctca aggaagccga cttggttcta ctagtgctaa atgccagtga
    10981 accactgact gcgcaagaca gacaacttct tgaaattagc caagatacca atcgcattat
    11041 tctacttaat aaaaccgacc tgccagaaac gattgaaact tcgaaactac ctgaagacgt
    11101 tatccgtatt tcagtcctta aaaaccaaaa catcgacaag attgaagagc gaatcaacaa
    11161 cctcttcttt gaaaatgctg gcttggtcga gcaagatgct acttacttgt caaacgcccg
    11221 tcacatttcc ctgattgaaa aagcagttga aagcctacaa gccgttaatc aaggtcttga
    11281 gctggggatg ccagttgatt tgcttcaagt tgacttgact cgtacttggg aaatcctcgg
    11341 agaaatcact ggggatgctg ctccagatga actcatcacc caactcttta gccaattctg
    11401 tttaggaaaa taagaaaaat ccatgatcct tcattcggtc atggatttta ttgtctttat
    11461 tagtaatctg gtcttaagac ccctgttaca gttgccttag ttgcttcgta gtcgccatct
    11521 acgacaacct tgataatgcg tttgacatct tcttctggtg ctggaacaag aggtagacga
    11581 gtgggtccag cttcaaatcc catatagtta agaattgcct taactggagc aggacttgga
    11641 taagagaaga gagcattaac cttaggaatg aatttacgct gaattgctgc ggctttcttc
    11701 atatcgcttt ctgcaatggc agtaaacatc tcgtgcattt catccccatt tgtatgagag
    11761 gcaacagaaa taaccccatc cgccccaagg ttcatggcat ggaaagcatc tccatcctca
    11821 cctgtataaa tcaagaactc ttcaggcttg tgctcaatca agtaagccat attagccaag
    11881 ctagtacatt ctttgacacc gataatattt ggatggtcag ccaagcgaag catggtttct
    11941 ggagtcaatt cgacaactac acgccctgga atgttataga taataattgg taggtcagaa
    12001 gcatctgcaa tagccttaaa gtgctgatac atcccttctt gagaaggttt gttgtagtaa
    12061 ggaacaatag caagcccagc tgcgaaacca ccaaattccg ctacttcttt gacaaactca
    12121 atagagtcac gcgtatcatt agtacctaca cccgcaatca aaggaacgcg tccattgaca
    12181 accttttgta cagccgcaaa caactccaac tcctcatcgt gggtcaaagt tggactctca
    12241 gcagtcgttc ctgcgagaag aattccatcc gtatgatggg ccaataaatg ctcaatcaag
    12301 gctggaatag catcaaagtt aatggaacca tcctcatgga agggggtaat aaaggctgta
    12361 atgattttac attcttttaa atcttgataa gacacgaaaa cacctctcta tttcaaagaa
    12421 ggagttcatc tgaactccta aacgatatga ctattttaat tcaaatttca attcggctgt
    12481 tggacgaacc aatccacgtt catgaagagt ttcagcaatc tgaactgagt tccaagcagc
    12541 acctttgaga aggttatctg aaacaaccca catgtgaatt cctttttctg aatccaagtc
    12601 tttacggata cgaccaacaa aggtatcacg cgaaccaact gcattgatag cttgaggata
    12661 gatttgatga gctacatcat cttcaagaac agcacctggg aaggctgcga tagctgcttt
    12721 tacttcttcg attggagcca cttcttttgt ttcgatataa acagactcag agtgagctga
    12781 caagactgga atacgcacac atgttgcaga tactgcaatg ctatcatctt ccataatttt
    12841 cttagtttcc ttggtcatct tcatctcttc gtacgtgtaa tcattatcag tgaaaacatc
    12901 aatttgtgga agagcgttaa aggcgatagg ataatgtttc ttgtcaccac ctgaaggcaa
    12961 gatttccgca tgcaaatcac gtggtttcac accatcattc aagacttcac gaagttcacg
    13021 ttgtgtctca agaattgctc ccataccagc acctgaaacg gcttgataag ttgaaacaat
    13081 gatacggtcc aagccccatt tttggcgaac cggctcaaga gccaccatca tttggattgt
    13141 tgaacaatta gggcaggcaa tgattccgtt gtgagcatca agtgcatgag cattgacctc
    13201 tggaacaacc aaaggaacat ctggattttg acggaaataa gatgtattat ctactactac
    13261 cacgccagct tttactgcgt atggtgcata cttagctgat gtagaactac ctgctgaaaa
    13321 gagagcaata tcaactcctt caaaagctgt ttcagtcgtt tcttcaattg taatatcttg
    13381 atctttaaat ttcaatgact tacctgctga acgtgcagaa gcaaggtaac gaattttatc
    13441 gattggaagt gttgattctt ccaacatttt tatcatctga gcaccgacag cacctgtcgc
    13501 gccgactaca gcaactgtat atcccataaa taacctcttt cggaattttc taaaaatttc
    13561 tataatagaa gtattatact actttttcca tgaattgcaa agctttttca tcattttttg
    13621 gaaaataaaa atcccagtcg ctagactagg gactaagagg catcttcatg tgatgagcag
    13681 gttcacacaa ctcatcaagg tccgctcctg cgttatgacc tccttatgct caatagtagt
    13741 ccgaagacta cctatcgact catcgcatat tctatattac tagagatact tgattttgtc
    13801 aataagaaat tttttcgatc gagtataaca aaaaactctc atattcaaga gtttccctat
    13861 acatatcatg ctaattgccg ggattgaacc ggcgacctca tccttaccat ggatgcgctc
    13921 tgccaactga gctaaatcag cttacttaag aagtatacta tattcagaaa aacttgtcaa
    13981 gtttccttag aaattttcca taggaaaaag ccaggtaaga actacctagc ttatcttctt
    14041 ctatttactt aaatcaattc gacgaccaat tttaccaata ataatcgccc caataatcaa
    14101 tgaagcaaat tcaccgattc ctgttgtaaa ccaagtaagg aagaatggta attctgctac
    14161 aatatttaac tctgcagcga tagtaaacat ggaaattgaa aagaggattg aaaagaagaa
    14221 atgatctttt cgaatcaatc cgttaaagag gtaatccttg ctatattttg caaaaagcca
    14281 aacacctaaa ctgaggaata ctaaggttga accaccacca acaaagacat ctagcagtcc
    14341 gaagctaaag aaattagcaa tcatacaacc gatggtaact ccgatgatgt acttaggatt
    14401 gtaaaaagcc ataaagttca tcatttctga aatacgaaac tgataagcac catagctgat
    14461 ggcatttagg ggcggtgtga cagtcaaaac gacgtagata gcagcgacga ttgcaatatc
    14521 tgcaacatca cgaatagtta attttttcat cttttctcct ttggcggtta tccgcgtgta
    14581 atatgcttgg tgaaagaagc taagcaccaa gggttgattc attcaacctt actagtatag
    14641 cacaatagcc tgctttatgc tatacttaaa gcatgaaaaa acctattcaa aaatttttta
    14701 acaatgaaat cttagcctat ctcttttttg gccttgcgac aactctagtt tcgattctct
    14761 cacgactagt catttatcaa ctaagtcatc aggaactcct tgctacggcc ttggcaaata
    14821 ttatcggtat cttatttgcc tttatcacaa atgatacgat tgtatttaag caaaaaaaga
    14881 aaaatagact tatccgttta gtgaaatttt ctcttgctcg cctttctact tttctgttag
    14941 acttgttttt aacttttctc tttgtaaccc aatttcctca catcataggg caattcgtaa
    15001 ctgaaaacat tgataagata aatgctattg aaacaataat tgcacaaata ttcattatta
    15061 tcatcaatta tatattgagc aaggtctata tttttagaaa ataatgctcc atttatgagc
    15121 cttttaattg ccttctataa tgatttagga tacaatgaaa cacgaaacat tgaaaggaaa
    15181 acagtatgtt aaaaaatcta aaatcgttct tgcttcgagg aaatgttatt gaccttgctg
    15241 tcggtgttgt cattgcctct gcttttggtg ctatcgttac ttcacttgta aacgacatta
    15301 tcactcctct tattttaaat cccgctttga aagctgctaa agtcgaacgt atcgctcaac
    15361 tttcttggca tggagtcggc tatggtaact ttttaagtgc tattatcaat tttatctttg
    15421 tgggtaccgc cctcttcttt attatcaagg gcattgaaaa agcacagaaa ctgactggca
    15481 taaagaaaga aaaaactgcc gaaaaaaaac caaccgaatt ggaagtcctt caagaaataa
    15541 aagctctcct tgagaaaaaa taatcgatta aaaggatcta gcgcaaagct aaatcctttt
    15601 ttctttactc tttgggtaac ttgcctgctt tttcaagcat ttttttgata agataaggca
    15661 tcttaatatt ctcccgccct tttttctcaa tcagtttttt cacaaattct ggcatttgta
    15721 aatcttcaga ttcagctaaa atgtttttcg tctcgtctga aggaactaac tcatcaaagg
    15781 tctcttcttc tgggagaaat tccttaaact cttgattttc attgactcta actgtattga
    15841 ccaaagcatc aatcaaacga gaatctgtat ttggcattgg tggacgatgg tagtttaccc
    15901 caaattcctg acataaatca taacattcca catcattgtc aaacaagacc tcaatatgct
    15961 cactgatgaa actaataggt acaaaaatat aatggtctgg atgttctgtc tgttctctga
    16021 gatactccaa aacatctggt ttaatccatg gaataccaat atcactctca ctctgccaag
    16081 tgttggtata ttgttctgaa ctcaagccca gtttttcagc gactagcttg ctattttcga
    16141 aaatttggtc tatataagga tctccaaagt ccaaggcaaa aataggcaca ctatgggctg
    16201 aaaagatgac tttaaagctg tcttgcttta cttcttcttt taaaatctta gcaatttcat
    16261 ctgcccaata gtttaagagc gcttcttcct gataccagtc cttaatgacc aaaaattgaa
    16321 tttgtttgct ttctaaaaat ttttcatagc ccatgacaga gtagaaagaa tagtggggct
    16381 ccaaaatcaa gcaaatacac tgttcaattc cgtctgcttc catttgaccg atcacatctg
    16441 gaataaaggg actggaaaac ttattagcaa agtagacact gtattcattc cccagcctag
    16501 cttctaccaa ggcaacctct tgacgggtaa ttttttgcag aggcgtgcct ccaattcgta
    16561 cataattatc atagagagtc tgaatctcgt ggtcttgggg tctcatccca cgacgaatat
    16621 ttgtgaaaaa atcagctaca ccttcaaagg taatctcttc tggtgaaccg aaggtcatca
    16681 ttaaaattgc ttttttcatg actgcttcct tgtgatgttt ttatcaagtt tattttatca
    16741 ttaattcatc gataagtaaa cgctagcata gggacattct caatcttctg tcttttgttt
    16801 ttctcttctt tctatgatac aatggaaaaa ataaattcaa aaggagtttt ttatgactta
    16861 tccaaatctc ttggaccgct tcttaaccta cgttaaggtc aacacgcgct ctgatgaaca
    16921 ctctactact actccaagta cacagagtca ggttgacttc gcaacaaatg tcctaattcc
    16981 tgaaatgaaa cgtgttggac tgcaaaatgt ttactatcta ccgaatggtt ttgctattgg
    17041 aaccttgcca gccaacgatc cgtctttaac acgtaagatt ggttttatat cgcacatgga
    17101 tactgctgat tttaatgctg aaggagtcaa tccacaggta attgaaaact acgatggtgg
    17161 tgtgattgaa ctagggaatt ctggtttcaa actcgatcca gccgacttca agagtcttga
    17221 aaaatatcca ggacaaacgc tcatcacaac agatggaaca accttgctag gtgctgatga
    17281 caagtcagga attgctgaaa ttatgacagc cattgaatat ctaactgctc atcctgaaat
    17341 taagcactgt gagattcgtg ttggttttgg tccagatgaa gaaatcggtg ttggtgccaa
    17401 taaatttgat gcagaagatt ttgatgtgga ttttgcctac actgttgatg gtggtccact
    17461 aggtgaactt cagtacgaga ctttctcagc cgctggtgct gaattgcatt tccaaggccg
    17521 taatgtccac cctggtactg ccaaagggca gatggtcaat gcccttcagc tagcaattga
    17581 ttttcataat caacttccag aaaatgaccg acctgagtta actgaaggtt accaaggttt
    17641 ttaccatcta atggatgtga caggtagtgt tgaggaggcg cgtgcaagct acatcattcg
    17701 tgattttgaa aaagatgcct ttgaagcgcg taaagcatcc atgcaatcta tcgctgataa
    17761 gatgaatgaa gaacttggga gcaaccgtgt cactctcaac ttgacagacc agtactacaa
    17821 tatgaaagaa gtcattgaaa aagatatgac tccaattacc attgctaaag ccgttatgga
    17881 agatctaggt atcacgccta ttatcgaacc aatccggggt ggaacagacg gctctaagat
    17941 ttcctttatg ggaatcccaa ctccgaatat ctttgcaggt ggcgaaaata tgcacggacg
    18001 ttttgaatac gttagccttc agactatgga acgtgcagtt gataccatca ttggcatcgt
    18061 agcttataaa ggctaaaaag acgaggtagc tcagctactt cgcctttctt tttattctac
    18121 tggtttttct tgatttccag tagttgtaga agattctgtt gttttatttt ctgaagttga
    18181 ttcagcaggt ttagaatctc ttgtattgct tggtttgttt tcgtcgctag cagtttcaat
    18241 gttagattct gcagttgcgt ttggttggtt ctcagcactg gtgttatcac catttgcttc
    18301 agcatttctt gctggacttg tttcttcact tgcgctagct tttgactgga tttgatgatt
    18361 caaaactaga atagcttttg tcgattcaag taaagctgtt ttgtctttac tattagcaga
    18421 aagttgatct aataatgcat ccaccttatc aaaagtccgc atcagatcca ttattacttt
    18481 ctaaataaaa gtgaagcgac atgagaatat cgtagagttt ttgatagagt acaagtgtct
    18541 gaggatcttg ctcagcattt tccttttctt gttgaagggc gctagcgata cgagtcaaga
    18601 catcttttac ctgactgttt acttcatcca agtctgcatc agccttgttt gtggcagctt
    18661 ttagattttc tacttcttct gccaaagatt gtctgattcc ttcttcatgg attcgttcca
    18721 agagttgatt tgccttgctc aaaagacttt ctacttcttc cttgctatct gtcgcagatt
    18781 attggttgct atctaccatg tactcctaaa acaggagagt tataatccaa gattacaagg
    18841 ccttacagaa ataagaaatc cagataagac aatgttcgtc caagacgcta ttcgcttcgc
    18901 acagcagcac ggattcaata tgctttaatt ttaaagttta ggtgtcaaga cctcttttta
    18961 gtgtgcccaa aatttagaga agtaatcaat caactaactt ttattttttt caaactttca
    19021 gtaaactgac ctaaagctaa ctcaatctgt ctttgttcga taggcttgtc tttgtagatg
    19081 cttctgctat cagctagaag ttgatctact tttgccaaga ctgccttctc atcaaaagtt
    19141 ccaggttgat agttggattg cagggatgga atcttgtttt tcaaagccgc ttcatatccc
    19201 ttagtttgaa ccttgatgta gtgattgtgg tcgccacgag gaatcacaaa accttctgaa
    19261 tcttcactta taattcgatt ggcatcaaaa ccatgaccat cttcttcctc atggtggaca
    19321 tgtagtgacg gattacttaa tacagaacta gaagaacttc ctaccttttc cgtgttagag
    19381 tgtgatgggg gattgttaag agatgactta ggaatatagt gatagtgacc ccatgtctta
    19441 ctatataagc atcacctgta tctctgacaa tatcattagg gttaaagaca taaccatcat
    19501 ctgctgcaga aacaccatta ttcggtgtca ccgacaaaga ttgactgaga gctgtagtat
    19561 tctctgataa ttatactttt gcagctgcta attcacctgc cgacaagtca ctctcaggaa
    19621 tgaaatgata gtgaccacca tgtggtacta tagtagattg aaatagaata tgagcaaatt
    19681 gataagggga ttttaaagta atttctaaca atgatttaga aactatgatg tgctattcta
    19741 aattcaactc actatatata accatcatcg gtagtataac gtccctgtaa ttttgctaca
    19801 gatacttctg cactagctcc tttatcgtct ttaccatgtt cttgtttttg gcgattgatt
    19861 tcatctttta ttcgtacatt ttctgcatga gcttgatctt taaggtaaac ataatacttt
    19921 ccatctacct taataatata tcctccctta acctaactga cgatatcttg atctttcggc
    19981 tgatagttgg gggctttcat taatagctct tcactaaaga gcgcatccaa aggaacttta
    20041 ccattatagc agtgataatg atcgccatga gaagttacat aaccttgatc tgtaatctta
    20101 ataacaattt gttttgcttg aattccttct ttttgactaa cctagtctgg agtcaaattt
    20161 tcagtcttct tagtgtcttt attactgttt acatatgaaa cacgattttt atctgtattg
    20221 gcctgttagc tatgttggtt cagagcataa acacacagac ttaaggaaag gataacaaca
    20281 gatccagctg ctatatattt ctttttaaat ttcataatta cctcatttct ataattattt
    20341 at
//
LOCUS       DAVKAU010000031        20280 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVKAU010000031 DAVKAU010000000
VERSION     DAVKAU010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20280
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.031"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..461)
                     /locus_tag="VWX48_001347"
     CDS             complement(<1..461)
                     /locus_tag="VWX48_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171966.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIK"
     gene            complement(427..990)
                     /locus_tag="VWX48_001348"
     CDS             complement(427..990)
                     /locus_tag="VWX48_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171967.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLVLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(1000..2988)
                     /gene="uvrB"
                     /locus_tag="VWX48_001349"
     CDS             complement(1000..2988)
                     /gene="uvrB"
                     /locus_tag="VWX48_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU9171968.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(3065..4018)
                     /locus_tag="VWX48_001350"
     CDS             complement(3065..4018)
                     /locus_tag="VWX48_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9171969.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            4188..6353
                     /locus_tag="VWX48_001351"
     CDS             4188..6353
                     /locus_tag="VWX48_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9171970.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            6353..7093
                     /locus_tag="VWX48_001352"
     CDS             6353..7093
                     /locus_tag="VWX48_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9171971.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            7242..8729
                     /locus_tag="VWX48_001353"
     CDS             7242..8729
                     /locus_tag="VWX48_001353"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU9171972.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDLEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPPHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(8773..10062)
                     /gene="ftsY"
                     /locus_tag="VWX48_001354"
     CDS             complement(8773..10062)
                     /gene="ftsY"
                     /locus_tag="VWX48_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU9171973.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTIEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(10066..10884)
                     /locus_tag="VWX48_001355"
     CDS             complement(10066..10884)
                     /locus_tag="VWX48_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9171974.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYADVARLYEKTE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(10884..11678)
                     /locus_tag="VWX48_001356"
     CDS             complement(10884..11678)
                     /locus_tag="VWX48_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9171975.1"
                     /translation="MTIKLVATDMDGTFLDENGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYI
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            complement(11675..15214)
                     /gene="smc"
                     /locus_tag="VWX48_001357"
     CDS             complement(11675..15214)
                     /gene="smc"
                     /locus_tag="VWX48_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU9171976.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQTQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEVALKTLQDEMARLTESLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDRYEEVHNRLDFLNSQRDDILSAKNLLLETITKMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(15205..15903)
                     /locus_tag="VWX48_001358"
     CDS             complement(15205..15903)
                     /locus_tag="VWX48_001358"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU9171977.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(16086..16157)
                     /locus_tag="VWX48_001359"
     tRNA            complement(16086..16157)
                     /locus_tag="VWX48_001359"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16122..16124),aa:Arg,seq:ccg)
     gene            complement(16221..17207)
                     /locus_tag="VWX48_001360"
     CDS             complement(16221..17207)
                     /locus_tag="VWX48_001360"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU9171978.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(17382..18698)
                     /locus_tag="VWX48_001361"
     CDS             complement(17382..18698)
                     /locus_tag="VWX48_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU9171979.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(18685..19944)
                     /locus_tag="VWX48_001362"
                     /pseudo
     CDS             complement(18685..19944)
                     /locus_tag="VWX48_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
BASE COUNT         5870 a         4545 c         3634 g         6231 t
ORIGIN      
        1 tcctttatag gctttccaag ttcaagtatt ttttcttgtc catcaaaagt aaaacccatt
       61 ttttgataga aagcaatggc gcgcttgtta tctttcaata cccataagaa aatttcagaa
      121 aaatgattaa gagcagtcaa agctgctttc attaactttt gtgcgatacc ttttccataa
      181 tagtctttta aaacatataa agcaataatt tcaccagctt gaatagtctc atcacgaaaa
      241 ttgccataac tgataaaacc aaccaccttc acgccatcca tcgcaatcaa tgtattttct
      301 ggatactttt gactaaagaa tcgacatctt tctaatgtca ttgtatcctg aaattccgca
      361 ggcaaaaggt catcataaga ctctctccac gtttgccagt gaacgaggga tttgccttct
      421 atctcttcag gagtttccat tgatttgata ataaccgtca tttattttct cccagtcttc
      481 tctcaaaata ccatatttaa tactatcaaa atatttacct tgataataac gaacttttgg
      541 aatatgagct tcttttttca ttcttaattt ttcagcaagt ttcatcatac caagatttcc
      601 tgaccaagtt gtcaaaacca gatgctccaa ctccaagtaa tcctgaaacg tcctatctat
      661 ccactgcaac atagcaactt tcccaatacc agtgttccag aattttttat cataaatacc
      721 aattcccaat tccatccatc ttgtttcttt acatacccaa taacgcgaaa cagtcccaac
      781 tagtttatca tcaacaaaaa taccaaggcg atttgagttg cttaaaatgg attctgattt
      841 ttgtagttcg aattctttaa aatttgaaaa atactgataa tcatcataat agggagcatc
      901 atactgtttc caaactggat taagttgtga ataagccatt tcccataaag acatcaaatc
      961 ttctctcttt aactttctta aataaatcat actattcccc taatccaagg ccttgacttc
     1021 caacatcata tcacggatct gagccgccag ttcaaagtca agcacttcga cggcttcttg
     1081 catttgtttt tctagtttct tgacgagttc tttgcgctct tgtttgttga ggctattgat
     1141 gtcgacttcc ttgtcctctt ccttagcaac tgccttggtc acggcaatca ggtcacggat
     1201 ttctttcttg attgtctgtg gtacgatacc atgctcttca ttataggcca tctgaatttt
     1261 ccgacggcgg gcagtttcat cgatagcacg ttgcatagac tgggtaaccg tgtctgcata
     1321 catgatgaca tggccttcac tgttacgagc agcacgtcca atagtctgga tgagtccacg
     1381 ttcgttgcga aggaaacctt ccttgtcagc atcgagaata gctacgaggc tcacttcagg
     1441 aacgtcaatt ccttcacgga gcaggttaat tccgaccaag acatcaaaga cacccaagcg
     1501 caggtcacgg ataatctccg tccgttccaa ggtcttgata tccgagtgca tgtacttgac
     1561 cttgataccc atttccttga agtagtcggt caaatcctct gccattttct tggtcaaagt
     1621 tgtgataaag gtacgctcat ttttttcaac gcgggcattg atttcaccca agaggtcatc
     1681 aatctgtccc atagtcggac ggacttccac ctctggatcc aagagtcccg ttggacgaat
     1741 gatttgctca atcactgtct cggtctgttc attttcatag tcaccaggtg tcgctgaaac
     1801 gtaaacaatc tgatgaacgt gactctcaaa ctcctcccga cggagaggac gattgtccaa
     1861 agcagacggc aaacggaaac cataattaac cagcatttct ttacgcgaac ggtctccatt
     1921 gtacatgccc ttgatttgcc ctatggtcat atgactctcg tcaatcataa tcaagaaatc
     1981 atctgggaag aagtcgagaa gcgtataagg aggctctcct tcgctccgtc catccatgtg
     2041 gcgagaataa ttttcaaccc cattggtata gcccatctca cgcaacattt cgatatcata
     2101 ctctgtccgc tgtttcaaac gctgggcttc aagcagttta ccttcctttt caaagacagc
     2161 taattgttct tccaactcgg cctgaatctt tgcaatggca acttccatgt ggtcgtcatt
     2221 ggtcacaaag tgtgtcgctg ggaaaatcgc taaatgatcc acttctccca acacctgacc
     2281 tgtcagagcc tcaacttcac gaatacggtc aatttcgtct ccaaaaaatt ctactcgaaa
     2341 ggcatgttca tctcgggaag ctgggaaaat ctctaccaca tccccacgaa cgcgaaatct
     2401 tccgcgttgg aaatcaatat cattgcgttc aaactgaata tcgaccaagt cattcaagag
     2461 tttatcacga gaaatctcta gaccaggacg gagactaacg acactatcag cgtattcctt
     2521 gggcgaaccc aaaccataga tacaagagac tgaggccacg acaataacat cattacgctc
     2581 caaaagggct gaggtagctg agtggcgaag cttgtcaatc tcgtcattga cagaactatc
     2641 cttctcaata taggtatcgc tagaagggac ataggcctct ggctggtaat aatcatagta
     2701 ggatacgaaa tactcaactg cattttcagg gaaaaattcc ttaaactccc catagagctg
     2761 accagccaga gttttattgt gggcaataac cagagttggt ttattgactt tagaaatgac
     2821 ctgactcata gtatacgtct tccctgttcc agtcgccccc atcagaatct gagctttttc
     2881 tcccccctca atgttatcca ccaactgctc gatagcttgg ggttgatctc ctgatggttg
     2941 atattttgat actagtttaa attgattatc tgtaatgtga ttgatcataa gaatcctctc
     3001 tccatgtgct attcctattt tagcatactt atagtatttt cacgaagaaa aggatggacc
     3061 gaagtcacat cctttcattt tctttcttta atttattagc aagatagaca atcagcagta
     3121 gtaataccag acttgtcata atggaacctt ctatgccaaa agaaccacct gatagccaat
     3181 cttgattgcc ttgtggtaaa aaggtcatca gagacgttcc tgacggttga ccactaacta
     3241 aaatcccaaa gagattaccc tgagcaaaat tccaagcacc atgaatacct gcaacacccc
     3301 aaactgtatc agttttgaga aggtaaagag ccatggcaac tccgaataaa aagagattta
     3361 ctagagatag aggggtgagg ccagaattgc ccatatgaag cagggtaaag aacaggctag
     3421 atataagaat agctagtttt agattggttc ttgaggccaa ttgaggaagt agccaagcac
     3481 gggccaccac ttcttctgct gtcccctgta aaatccaaaa tgggatagta aagacgacaa
     3541 aggcaagaga ataaggattc aagtgaatgg attccaaacg atattgacct aagaccacca
     3601 aacctaacaa ggtcagaaga aaaagtgcca gacctagact aaatcctttc agaagattgc
     3661 tgaggaaatt ctctctataa aatcccaagg ttcgaatagg tcttttctca acttttcttg
     3721 tccatctgaa cacagtgtta agaataaaac caaaggccag taatcctaaa attaaacgaa
     3781 agtcacttgt tttatccgtc aagctctgat gcaaggtctg caagtagctt gcaagatttt
     3841 gaccagcctc tccaaaattt ctagcaagtc cgatgagagc taacaagcca ataccataca
     3901 aagtaaaagc cacaaactct cctatgaaga caaaaacaaa ggctaacaag gggcttgtgt
     3961 aaatgtttaa actcattttt gaagcttgga agtctttaaa tattcttttg ttcttcatat
     4021 ccccgtcctc ttttcttcta tatatactat tattatagca ctttttaata gcaattcaaa
     4081 gaaaggaaaa aatcaatgtt atattttctg acacgaaaaa tataaaaatt tgcctttttt
     4141 tactttttct gatataatga gagaatattc ggaaaaggag actaaaaatg aagaaaaaat
     4201 ttctagcatt tttgctaatt ttattcccaa ttttctcatt aggtattgcc aaagcagaaa
     4261 cgattaagat tgtttctgat accgcctatg caccttttga gtttaaagat tcagatcaaa
     4321 cttataaagg aattgatgtt gacattatta acaaagtcgc tgagattaaa ggctggaaca
     4381 ttcagatgtc ctatcctgga tttgacgcag cagtcaatgc ggttcaagct gggcaagccg
     4441 acgctatcat ggcagggatg acaaagacta aagaacgtga aaaagtcttc accatgtctg
     4501 atacttacta tgatacaaaa gttgtcattg ctactacaaa gtcacacaaa attagcaagt
     4561 acgaccaatt aactggcaaa accgttggtg ttaaaaacgg aactgccgct caacgtttcc
     4621 ttgaaacaat caaagataaa tacggcttta ctattaaaac atttgacact ggggatttaa
     4681 tgaacaacag cttgagtgct ggtgccatcg atgccatgat ggatgacaaa cctgttatcg
     4741 aatatgccat taaccaaggt caagacctcc atattgaaat ggatggtgaa gctgtaggaa
     4801 gttttgcttt cggtgtgaaa aaaggaagta aatacgaaca cctggttact gaatttaacc
     4861 aagccttggc tgaaatgaaa aaagatggta gtcttgataa aattatcaag aaatggactg
     4921 cttcatcatc ttcagcagtg ccaactacaa ccactctcgc aggattaaaa gctattcctg
     4981 ttaaggctaa atatatcatt gccagcgatt cttcttttgc accttttgtt ttccaaaatt
     5041 caagcaacca atacactggt attgatatgg aattgattaa ggcaatcgct aaagaccaag
     5101 gttttgaaat tgaaatcacc aaccctggtt ttgatgctgc tatcagtgct gtccaagctg
     5161 gtcaagccga tggtatcatt gctggtatgt ctgtcacaga tgctcgtaag gcaacttttg
     5221 acttctcaga atcatactac actgctaata ccattcttgg tgtcaaagaa tcaagcaata
     5281 ttgcttctta tgaagatcta aaaggaaaga cagtcggtgt taaaaacgga actgcttctc
     5341 aaaccttcct aacagaaaat caaagcaaat acggttacaa aatcaaaacc tttgctgatg
     5401 gttcttcaat gtatgacagt ttaaacactg gtgccattga tgccgttatg gatgatgaac
     5461 ctgttctcaa atattctatc agccaaggtc aaaaattgaa aactccaatc tctggaactc
     5521 caatcggtga aacagccttt gccgttaaaa aaggagcaaa tccagaactg attgaaatgt
     5581 tcaacaacgg acttgcaaac cttaaagcaa acggtgaatt ccaaaagatt cttgacaaat
     5641 acctagctag cgaatcttca actgcttcaa caagtactgt tgacgaaaca acgctctggg
     5701 gcttgcttca aaacaactac aaacaactcc ttagcggtct tggtatcact cttgctctag
     5761 ctcttatctc atttgctatt gccattgtca tcggaattat cttcggtatg tttagcgtta
     5821 gcccatacaa atctcttcgc gtcatctctg agattttcgt tgacgttatt cgtggtattc
     5881 cattgatgat tcttgcagcc ttcatcttct ggggaattcc aaacttcatc gagtctatca
     5941 caggccaaca aagcccaatt aacgactttg tagctggaac aattgccctc tcactcaatg
     6001 cggctgctta tatcgctgaa atcgttcgtg gtggtattca ggccgttcca gttggccaaa
     6061 tggaagccag ccgaagcttg ggtatctctt atggaaaaac catgcgtaag attatcttgc
     6121 cacaagcaac taaattgatg ttgccaaact ttgtcaacca attcgttatc gctcttaaag
     6181 atacaactat cgtatctgct atcggtttgg ttgaactctt ccaaactggt aagattatca
     6241 ttgctcgtaa ctaccaaagt ttcaagatgt atgcaatcct tgctatcttc tatcttgtaa
     6301 ttatcacact tttgactaga ctagcgaaac gcttagaaaa gaggattcgt taatggcaaa
     6361 attaaaaatt gatgtaaatg atttacacaa gcactatgga aaaaatgaag tcctaaaagg
     6421 aattacgact aagttctatg aaggagatgt tgtttgtatc atcggtcctt caggttctgg
     6481 taagtcaact ttcctccgta gcctcaatct tttagaagaa gtcactagcg gtcacatcac
     6541 tgtgaacggc tatgatttaa ctgaaaaaac aaccaatgtt gaccacgtcc gtgaaaatat
     6601 cggcatggta ttccaacact tcaacctctt ccctcatatg tctgtattgg acaacatcac
     6661 ctttgctcct attgagcaca agttgatgac taaggaagaa gctgaggaat tgggaatgga
     6721 gttgcttgaa aaggttggac tagcagataa agctaatgcc aatccagata gcctatcagg
     6781 tggtcaaaaa caacgtgtgg ccatcgctcg tggcctagca atgaatccag acatcatgct
     6841 cttcgatgaa ccaacttctg cccttgaccc tgagatggtt ggagacgtac ttaacgttat
     6901 gaaggaattg gctgagcaag gcatgaccat gattatcgta acccatgaga tgggatttgc
     6961 tcgtcaggtt gccaaccgcg ttatctttac tgcagatggc gagttccttg aagacggaac
     7021 acctgaccaa atctttgata acccacaaca ccctcgtctg aaagagttct tagataaggt
     7081 cttaaacgtc taaactcaaa ctgtaaggat ttccttgcag tttttctacc tcgtattgga
     7141 atttttgatt tttcggaaaa ttatgttaga attaagttta tgaaatgagg tttcctcata
     7201 cctagcaaga ctaggaataa aaatagaaat taggtagcta gatgtcatct aaggttattg
     7261 ttacaatttt cggtgcgagt ggagacctgg ctaaacgcaa gctctaccct tcccttttta
     7321 gactatataa atccggcaat ctttccaagc actttgccgt tattggaact gcccgtagac
     7381 cttggagtaa ggaatatttt gaatctgtag ttgtcgagtc catccttgat ttggcagata
     7441 gtaccgagca agcccaagaa tttgctagcc acttctacta tcaaagccat gatgtcaatg
     7501 atttggaaca ttatattgct ttgcgtcaat tacaagctga gcttaatgaa aaataccaag
     7561 ctgaacacaa taagctcttc ttcttgtcta tggcacctca gttctttgga accattgcca
     7621 aacacctcaa atctgaaaac attgtcgatg gcaaaggttt tgagcgcttg atcgttgaaa
     7681 aaccatttgg tacagattac gcaactgcaa gcaagttgaa tgacgaactc ctagcaacat
     7741 ttgacgaaga acaaattttc cgtattgacc attatcttgg taaggaaatg atccaaagca
     7801 tctttgcagt tcgctttgca aacttgattt ttgaaaacgt ttggaacaag gattttatcg
     7861 acaatgttca aattaccttt gcggagcgct tgggtgtaga agaacgtggt ggctactatg
     7921 accaatccgg tgccctccgt gacatggtcc aaaaccacac tctacaactt ctttcgctcc
     7981 tcgccatgga caaaccagca agcttcacaa aagacgagat tcgtgctgaa aagattaagg
     8041 tctttaaaaa cctctatcat ccaactgatg aagaactcaa agaacacttt atccgtggac
     8101 aataccgctc tggtaagatt gatggcatga aatacatctc ttatcgtagc gaaccaaatg
     8161 tgaatccaga atcaacaact gaaaccttta catctggtgc cttctttgta gacagcgatc
     8221 gattccgtgg tgttcctttc tttttccgta caggtaaacg actgactgaa aaaggaactc
     8281 atgtcaacat cgtctttaaa caaatggatt ctatatttgg agaaccactt gctccaaata
     8341 ttttgaccat ctatattcaa ccaacagaag gcttctctct tagcctaaat gggaagcaag
     8401 taggagaaga atttaacttg gctcctaact cacttgatta tcgtacagac gcgactgcaa
     8461 ctggtgcttc tccagaacca tacgagaaat tgatttatga tgtcctaaat aacaactcaa
     8521 ctaactttag ccactgggat gaggttggtg cgtcatggaa gttgattgac cgtattgaag
     8581 agctctgggc cgaaaatggt gccccacctc atgactataa agctggaagc atgggacctc
     8641 aagccagctt tgacctactt gaaaaattcg atgccaaatg gacttggcaa ccagatatcg
     8701 cctatcgtca agatggtcgt ttcgaataaa aaaatcctgc aagtttgtac cttgcaggat
     8761 ttttgcttct gattagatta agccttccaa gagacctttc ataaagtttt ctgagttaaa
     8821 ctctccaata tcatcgattt tttcaccaaa accaatcaat tttacaggaa tattgagttc
     8881 ttcacgaatg gctagaacca cacctcctcg agcagttcca tcaatcttag tcaaaacaat
     8941 tcccgttaaa ggtgtgattt tcgaaaattc tttggcctgt actagggcat tttgacctgt
     9001 tgatgcatca agtgccaaga aggtttcatg tggtgcttct ggcacaacac gtttgataat
     9061 acgaccaatc ttttccaact cagccataag gttatcctta ttttgcagac gaccagcagt
     9121 atcaatcatg agaatatcga taccttcagc cacggcacgt tccataccat caaagaccac
     9181 gctggctgga tcagcttttt caggtccagt tactactgga acatctactc gtcggcccca
     9241 ttcagctagc tgagctactg cacccgcacg gaaggtatct gctgcaacca gcatgacctt
     9301 cttaccagtt cgtttgtagc ggtgggctag ttttccaata gaagttgttt tcccaacacc
     9361 attcacacca acaaagagca taactgtcaa gttatcttgg aagtggatgc tttcatcgta
     9421 gctaccatcc ttttcataaa gctcaaccaa tttctcaatg atgacacgac gaagtgcatc
     9481 aggtttcttg gcattttcaa gcttggcttc gtaacgtagt tcctccgtta agttagaagc
     9541 gacttggaca ccaacatcac tcataatcag cagttcttcc agttcctcga aaaattcttc
     9601 gtcaacagag cggaagttag caaagaaggc gttcaagcga gcaccgaagc ccgtacgagt
     9661 cttcttgaga ctgcggtcat atttttcctg aacagtttct tctgtttgag gcctttctgg
     9721 ttcaagaact tcagaattat tttcttctat agttccttcg tgctcaagct tctcttcctc
     9781 tggtaattct tctgagtttg gtaattcttc tatttcttct tgagaaaccc ctacagctgg
     9841 ctctgaatcc tgactttctt caactgtgtc ttggatttcc tcctcttgga acacagcttg
     9901 ttcaacaatt tcaacctctg cttcttcctg aggaacttcc tcaacttctg tgaaggtagg
     9961 atcaacatct tcagacaaat caagattttc cagagcttct tttacaactt cttcgatttt
    10021 aggttcttct ttttttccga atagacggtc aaacaatccc atatcttagt tctcctttag
    10081 cacatattct tcgatagccc aggcgacagc ttcctcatcg ttggtcatcg gcgttactac
    10141 atttgcggct gcctttactt caggaacagc gttttgcata gcaacaccaa gacctgccca
    10201 ttcaatcata gaaaggtcat tggcctcgtc accacaggcc ataacttggc tttggttgat
    10261 tccaagatgg ctgattagtt ttgccaaacc tgttgcttta tgaacattct ttggtgacca
    10321 ctctagcaac atttcacgtg atttaaagat ttcatattgg tcaaacaatt ctggagaaat
    10381 cttctgaatg gctgcatcca agggttcttg agcaaaggca gtcacgcatt tgttgtaggt
    10441 catttgacta gacaggtctt caaagtcaac tggaacaaaa gtcaaagctg gattgaattt
    10501 ggcataaaga ctttcttggt ccgattggat ttgataaact gttccttctg agatggcatc
    10561 aagtggcagt gataatttct ctgttttctc atacaagcgt gccacatcag catatgaaaa
    10621 gactgtttta tcaaggattt cacctgtatt tttctgaacc aaaccaccat taaaagtaat
    10681 ggtatactca tcttcctgac cgtcagtccc taactcatgg agaaagaagt ccatggcttt
    10741 taagggacga ccagttgtca atacgacctt gataccacga tcacgcgcag ctttcaaagt
    10801 tgccttggtg cgatccgtca gccttttatc agtagtcagc aaggtaccgt ccaagtccaa
    10861 tgcgattaat tttatatctg ccattataag ccctccatat aagctataac cgactggtcc
    10921 ttatggtgac caatcacagt ctttgctaat tctaaaatct ctggtcgtgc attttcagga
    10981 gctacaggat gtcccacaac ctgcatcata tgtaagtcat taagattgtc tccaaaagcc
    11041 atgacctgat ccattgtgat gccaagtttt ttagctaatt caacaatagc tacaccctta
    11101 tcgacatagt ccagaacaat atcaatagat tcaaagccag ttgtcatagc cttgacacca
    11161 gggacattat cattgaccca agcttcacca gcttctagcg tttcttctgt gaagttggtt
    11221 gtaaatttga aaatgtcatc tgtgatatct tccaaactcg ctactttttg gatattttca
    11281 ttataatgct gactcacttt caaataggtc tcatcaaccg tatctagaac atatgaaccc
    11341 ttcttacccg tcaagagcag tttattgata tctatataag gtgacgtttt cagcttttca
    11401 aaagttgcca gataaaagtc acgagacata gtcgcttcat acaagtcctg accttgatac
    11461 tctaccaaac tgccattttc cgcgatgaaa ataatgtcat cacgaacacc agcaaataat
    11521 ttttccagag acagaaatcc ccgacccgaa gccaccgcaa agtaaatccc tttttccttg
    11581 taggaaacca agagagactt gaggcggtcc atatcaaagc gcccattctc atctaggaag
    11641 gttccgtcca tatccgttgc tactagttta attgtcatcc ttcaatactt tctaaatctt
    11701 ttaacttaac tgaaacaatc tttgaaacac ccgattcttg catggtcact ccatagatgg
    11761 aatcggccgc tgccatggtt cccttacggt gggttacgac gataaactgg ctgtccttgt
    11821 caaagcggtt gaggtaatcc ccaaaacgtt taacattggc ttcatccagc gcagcttcca
    11881 cctcatccaa gatgacaaaa ggaatggtct tgacacgaat aatggagaaa agcaaggcaa
    11941 gagccgatag ggctttttca ccaccactca tgaggttaag cgactggatt ttcttacctg
    12001 gaggttgaac agaaatctcc acaccagctg ttaaaaggtc gccctcagtc aatatcaagt
    12061 ctgcctgacc tccgccaaac atctgcttga aggtcacttt aaaggactca cgaatagctt
    12121 caaaggttga tttaaagcgt tccttaacct catcattcat ctttgtaatg gtttcaagga
    12181 gcagattttt cgctgacaaa atatcatctc gctgactatt tagaaagtcc agacggttgt
    12241 gaacttcttc gtaccggtca atagcttcta tattgacagg acccagtgag cgaatagcct
    12301 tctctaaatc cttaacttct tgctctgcca gattgaggtt ttccaattca tgcgcttttt
    12361 ctagagcttc agtatagcta atctggtact ggtctgttaa ttgactttgt agatggcgca
    12421 agcgctcgct gaccttttct ttcttagctt cagcacgtgt ttgcttgcga atccactcct
    12481 cattctgctg gcgagcctga tccaaatgac tagcaatatc atccagctga ccttctatat
    12541 catccaactc aaactgtttg cgaatcaaac cttgttggag gttcgttttc tgagttttgg
    12601 attcttccgc ctgttgactg agcaattctg tatcaacctt ctcaagattg tcaacctttt
    12661 cttgaagaag gcgctggatt tcctcttgtt caaaatcaag attgtccaat tccttgccta
    12721 agcgttcaat atcagcaact tcataacgtt tttgcccttg cagttctgtc ttaagcaaac
    12781 gagcttgcgc tagctcttcc tgcaagtttt gatagcgttc ttggatggca tttttattag
    12841 acttaatctc ttcaatctca gcttccagat tttgcttgtc actggcgatt gcagcaagac
    12901 gctcttggca tttttcctta tccgcttgcc aatctccctc ggaaagacga tctatttcct
    12961 cttcttggag tttccaaaga gtttccagtt cttcaacttg ctgactagtt tgctgataag
    13021 cgagggacaa gccttgctcc tgaatacgtg cctgctctcc ttgagattta atagcttcta
    13081 atgactcggt caatctggcc atctcatctt gcaaggtctt caaagccact tcttctgaac
    13141 ccaagcttgc ttcttcttca gcaatttctt tttgtaattg ctccagttct ggcttgatga
    13201 agatgctgtt gttctgacga ttggctccac ctgcatagga accacctgta cgaagctctg
    13261 tcccatccaa tgtcaccatg cgaacctgat aacgaacttg tcgagcagct tcacgcgcat
    13321 gttctacggt atcaaagata gccgtcgtag ctagcaagtt cttgaaaatg gcttccagtc
    13381 tagtatcaaa agtcaccaac tcatctgcca tcccaaggaa acctgggctt acagcgatag
    13441 catcttggtt ctgactagaa atcgtacgcg ccttaatagt ggtcaaagga agaaaggttg
    13501 cacgaccggc tctgtttcgt ttgaggaaat caatagcttt ggttgccgac tcttcatctt
    13561 ctacgatgat atgctggcta cttgccccta aggcaatctc tagggcagtt tgataataaa
    13621 catcaaaggt cagatgctca ctgactgcac caataatccc acctaggcga tctttttctt
    13681 ggagaacact cttaacacct gcataaaagt tgctatgatt tctcaggata ttttccaaac
    13741 tttgagctct ggcctgcttg tttttgagac tatccagacg gtcaaagagt tgagtttgtt
    13801 gagcttgata ggaagttttc tgctcctctt gctccttggc aatagcttgg tagtcagcca
    13861 ataatttctg aacctgctcc ttggcagttt caagctcttc cttttgctga ctagccttct
    13921 ctttagctat agctaattgc tctttcagct tttctagttg atctgcttgt ttttgagaaa
    13981 gctgacgact attttccaac tcattctcaa tacgggtcaa ctggtttgag acatccgctt
    14041 cttcttgtaa aagagctaca aagcgttcac gtaagagctc aatcatctga tcaggatcgt
    14101 ctgagaaagc cagcaattca gcttctaaac gattgagttt ttgattattt tggactagat
    14161 ttccctctaa cagagctaaa gagctttctt tatcagactt ttctttgctg agtgaatttc
    14221 tcttatcctc caaagcagcc aaacgggctt gtgcctcctg ttgattcagg gccacttgct
    14281 cggactccag tttcgatagg gctaattttc tttctaaatc actaatcaga ctagtcaagt
    14341 ccatcaaact gccttggtct ttggccattt cagcctgtaa atcttggcgt tgctttttaa
    14401 gagtttgatt ttcttcttct aatttttcac gcttttggta ataactcatc aagagttctt
    14461 gaacctgagc caactcttct tctgtcgact ctagttctgc cttattttcc ttgatttgag
    14521 caaccagaac gtctaaataa atagccttac gttgtccttc caagtctaaa aacttacggg
    14581 cattctcagc ttgcttctca agaggcttga tttgattatc caactcgtag ataatgtcct
    14641 ctaagcggtc cagattatcc tgagtttgtt gcagtttact ctcagtttct tttctacgag
    14701 tcttgtattt taaaactcct gcagcttctt caaaaatagc ccggcgttcc tcaggcttag
    14761 aattaaaaat ctcctcaacc ttgccttggg aaatgataga gaaggaatct cgtcccaatc
    14821 cagtatccaa gaagaggtca tgaatatcac gcagacggac tttcttgccg tcaatcttgt
    14881 attcgctatc tccactacga tagatatggc gttccaccct gatttcttga cctgcatcct
    14941 tgataaatcc gtcatgatta tccagagtca caactacaga agcataattg agcggtttgc
    15001 gactttcggt tccagcaaag atgacatccg gcatcttgcc cccacggaga ctcttgacac
    15061 tagactcccc caaagcccaa cgcagacttt ctgtaatatt ggactttcca gatccattgg
    15121 gtccaacaac tgccgtcaca ccttggtcaa aaacgacctt ggtcttatca gcaaaagact
    15181 tgaacccctg aatttcgatt tcctttaaat acatgaatcc agccccttct caacggcatt
    15241 tttggcagct tcctgctctg ctaatttctt agaacgacct tggccttgac cgatgctctt
    15301 accttcaaca agaacttcta catcaaagac cttatcgtga gcaggccctg tttcagaaat
    15361 cacctgataa cgaatagcca catcaccatt gacctgaagc aactcttgga gatgggtttt
    15421 atagtctgta atcatctcaa actcgcctgc ttcaacctta ggaatcatga cttgatagat
    15481 aaattccttg accttggcca catccttatc caaaagaagg gcaccaagaa aggcttcaaa
    15541 ggcatcacca agaatggtgt cacgattgcg accaccagat ttttcttccc ctttacccaa
    15601 cttgataaac tggtcaaact ggcaatcacg cgcaaaacca gctaaactct cctcacggac
    15661 aatcatagca cggagttttg ataggtcacc ttcaggcttt ttaggatatt ttttatatag
    15721 atattctgaa atcaataact gtagaacagc gtctcctaaa aattccaagc gttcattgtg
    15781 tgaaattttt aagaggcggt gctcattggc ataactcgta tgagtaaagg cagtttccag
    15841 taaatttttg tctgcaaatt cgattgcaaa atgattcttt agtacagttt gtaattcttt
    15901 cataccaacc tctttctaac tgataatagt cctttttatt atatcaaaaa aagccccctg
    15961 agtcactcta aaacgggact ggaaagcatt tgggaattct ttagacagag attctcagtt
    16021 ttagcgacaa atttgggtca ggataaagaa aaaagcccta ttaaaggctt tttaggatgt
    16081 ttacatccac cctgagggaa tcgaaccccc atctcaagaa ccggaatctt acgtgatatc
    16141 cattacacta agggtggaaa cttgttttat tataacagaa atttgctcta ataacaagtt
    16201 ttttggtcaa agaccccgtc ttagtgggaa gcatccccat tccagatgga gtttttcacg
    16261 atcacataat caacgtgttt aaggtcagca acctgacgtc cacctgcata agaaatagca
    16321 ctttgaaggt cttgttccat ctcagttaaa gtgtcttgca gatgaccttt agcaggaagc
    16381 aagatacgtt tgccttccac atttttgtaa gcaccttttt gatattgtga ggctgaacca
    16441 taatattctt tgaactgttc accatcgact tcaatcgttt tccctggact ttcaatgtgt
    16501 cctgcaaaga gggaaccaat catgatcatg ctagcaccga agcggataga cttagcaata
    16561 tcaccgtgag tacgaattcc tccatcagcg ataatcggtt tacgcgcagc cttggcacac
    16621 cagcgtagag cagccaactg ccaaccacct gtaccaaaac cagtcttaac cttggtgata
    16681 caaaccttac caggaccgat tccgacctta gtagcatccg caccagcatt ttccaattca
    16741 cgcacagctt ctggtgttcc cacatttcca gcaatgacaa aggtatctgg caattctttc
    16801 ttgatgtgtt gaatcataga aatcacgcta tccgcatgac catgagcaat atcaatagtg
    16861 atatactcag gagcatcagc cttgagctgg ctaacaaaat catactcata atccttaaca
    16921 ccgacagaga tagaagcaat gagcccttga tcgtgcattc gtttaataaa aggaatgcgt
    16981 cctgcctcat caaaacggtg cataatgtag aagtaaccac ctttagccag ttgctctgct
    17041 acattttcat ccaaaatcgt ctgcatattc gctggcacaa caggtagttt aaaggtgtga
    17101 tttcctaaag tgacacttgt atccgcttct gcacggcttt taatgacaca tttatttgga
    17161 atcaattgaa tatcttcgta atcaaaaatt ggaaattcat ttaacatatc gatgtctcgt
    17221 ttcttttgta atgacctacc tatgctcttg catcactacg ccttttccga cgtttcctta
    17281 atttattata aaccaaagta cagtttttgt caaattattt tatgaattaa aatatatcgt
    17341 tcgggtttta cttgtgttaa aaataaaaga aagaggggaa attattttct ccccacttct
    17401 tcatcaataa tcgctttaaa attttcttct gaattttcca tcattttaca aaatgtacta
    17461 tagaatgagg cattctgagg gattcgaata gaccacttct tcaattgagc tccatagcca
    17521 gctacttttc ctatttcact atttactgac tgctccatac taggaaaaat cagtccagcc
    17581 ttctcagctt ttaaaatata agaataggaa atcagctgga ataagtcctc acggttgatt
    17641 cctttttcag tcaattccag ttttttatat tttgcatcta gaacaatctt tcgttctctg
    17701 tcataaaaat ctggatatac ttttcgtttc ccaacagaaa atactgaaat tccatccgtc
    17761 ttatccttat ttctgggatg tacaaaacct tttggcaaca aggtgtaaac atactcttcc
    17821 caaagccagg caacatcaaa gagaatacca tagatttttt gatcttgata ccctaaaccg
    17881 tgcttttctt ggtttaggat catcagacaa agttcttgta agtttctgta ctcgtgaaag
    17941 tatgcatgac gtataggttt agattgattt ccccgaataa tcttagcacg atcagctagt
    18001 ttataagagg gcgttacacg cacgatttca gatacgtttt cacgactagt tgagagatta
    18061 tctagtaccc cttgaccaat gcttttctga ttcttaatgt attcaatagt gtgacggacc
    18121 aactgcatga ggggattatc ataggtgaac tctctcgttg cgtaggcaat atttcccgtg
    18181 aaaggaagat ttttcttgag atggtttctt acatcaatca ctcccttaac atgactgtcg
    18241 ttatgagaaa atcgatgata ttccttataa agaccttttc gaatagcagc ttgtagatac
    18301 ttgggaaaga gatacaccaa aagttgataa agcctctctt cacgagacaa agcaacatct
    18361 aaactagtga gattgatata aagaaccttg tttaagagat aatgcaaaaa atggtcatta
    18421 ctctcatcag aaaatcgtga ggaaatcgtt aatctttcct gaccatatcc aagaaaacca
    18481 atcacgttcc ctgtcttgat tttctgattg actgtttcaa aaatcttttg gtccttatcc
    18541 aaatcaggag tatgagtcaa atcatttgga aaaatgaaaa tacgttcatc ttgggataga
    18601 ctttccaagg ttctgtctaa aagaagattg cttagtttag gatattcttc aacaaatttt
    18661 tctttaataa tcttgtgttg attatcagta atccgcatca tcgttttcat cgccttcatt
    18721 gtcatcagct actgcctgat ctttttgctc attatttgtc agttcaaatg cttttttcaa
    18781 agtttccaaa gtttcaacct catcataaga acctcgcaag tagtcttcta ggagaggctt
    18841 aatataatca gaccagagta attcatagtc aaaatctaca tccttcaact taagaaaata
    18901 acttggtcca atatgataat gactgtttaa ttcctgaaca ttttcgatag cagcgttcaa
    18961 gtttcttaga cgaatttttg cttcttctgc atggatattc agctctttat ccaacatgcc
    19021 aacttgaccc tcggcagtaa cttcaacaaa acgaaaacga cgacgcatag caaaatcaaa
    19081 ggtatccact gaacgatcaa tgtcattcat agttccgatg atgtagacat tttcggggat
    19141 atagaacttt tcatcagttt cgtgtagatt tgcatattgg gtagaaacac ttcctttttc
    19201 accacgatag ccagggtcga tagagaaaaa gagttcgcca aaaatcttag aaatctcccc
    19261 acgattgatt tcatcgatga tgaagacgaa tttcttatca gtatcaattt ctgttgggga
    19321 aacatagtct ttcaaaccaa atctctttct caatgtttct aggacagttt ttccaccact
    19381 tttgtagtat tcttgcttat tataattttt atctttatac aactcgtaaa catatttgct
    19441 aggtagtgac catcctggaa caccactatc ataatttact gacaaatttt gtctactatt
    19501 aacagataag taagatgttt ttgttatata ttctttttct tcagcaacat ttatatattc
    19561 taagtaagaa tcccaagcct catcaaaatt atcttgtcct ccaatcaatt gggtttcttt
    19621 tgctttctga caaaaatctt taaaaatacc gtcctgtagc ctaaactcaa tagctccatc
    19681 cccatttgat actggtctta aaccttctac aaaatccgta taatcatagg atgggtgaaa
    19741 ttgtacaaat ccgatttggt cttcgttgcc atccgttaat tctttggcaa tttctttagc
    19801 aagataagtc tttcctgtgc caggagcacc acggaggatg aggtttttgg attgtaataa
    19861 gatattctta tactcgttga tattttctga catgtttatc tcttcctttt ctgattctct
    19921 ataaaaacta gtgaaattat cataaaactc ttttaaaata tcgttaggtt cagcagttga
    19981 ttccaactct aagtccttga caaagtattt ataatctaaa tcttcatctc gattattact
    20041 ataccttttt actattttaa attctgtgag tttaaatctc tgaaaaccac atcttatatt
    20101 tatccatgag ttatccatgt cactcagccg ataaccaaag taaggtgatt taatatatcc
    20161 attaccactc tttggaccaa aatgacctgt gttaagcatt tcaactttgt acagaatacc
    20221 ctcaatagtc agagcagggt aaatatgttc agctccatct aatttttgag aacgtttaat
//
LOCUS       DAVKAU010000032        20173 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVKAU010000032 DAVKAU010000000
VERSION     DAVKAU010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20173
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.032"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            61..1367
                     /locus_tag="VWX48_001363"
                     /pseudo
     CDS             61..1367
                     /locus_tag="VWX48_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1418..1576)
                     /locus_tag="VWX48_001364"
     CDS             complement(1418..1576)
                     /locus_tag="VWX48_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171980.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(1586..2896)
                     /gene="obgE"
                     /locus_tag="VWX48_001365"
     CDS             complement(1586..2896)
                     /gene="obgE"
                     /locus_tag="VWX48_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU9171981.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(2960..3094)
                     /locus_tag="VWX48_001366"
     CDS             complement(2960..3094)
                     /locus_tag="VWX48_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU9171982.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(3153..3329)
                     /locus_tag="VWX48_001367"
     CDS             complement(3153..3329)
                     /locus_tag="VWX48_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9171983.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(3360..4685)
                     /locus_tag="VWX48_001368"
     CDS             complement(3360..4685)
                     /locus_tag="VWX48_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU9171984.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKIKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(4701..5744)
                     /gene="cpoA"
                     /locus_tag="VWX48_001369"
     CDS             complement(4701..5744)
                     /gene="cpoA"
                     /locus_tag="VWX48_001369"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU9171985.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(5859..6188)
                     /locus_tag="VWX48_001370"
     CDS             complement(5859..6188)
                     /locus_tag="VWX48_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9171986.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(6202..7311)
                     /gene="rpoD"
                     /locus_tag="VWX48_001371"
     CDS             complement(6202..7311)
                     /gene="rpoD"
                     /locus_tag="VWX48_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU9171987.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(7314..9074)
                     /gene="dnaG"
                     /locus_tag="VWX48_001372"
     CDS             complement(7314..9074)
                     /gene="dnaG"
                     /locus_tag="VWX48_001372"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU9171988.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQDLYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGKLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(9164..9922)
                     /locus_tag="VWX48_001373"
     CDS             complement(9164..9922)
                     /locus_tag="VWX48_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9171989.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(9919..10785)
                     /locus_tag="VWX48_001374"
     CDS             complement(9919..10785)
                     /locus_tag="VWX48_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9171990.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLLTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(10854..11858)
                     /locus_tag="VWX48_001375"
     CDS             complement(10854..11858)
                     /locus_tag="VWX48_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9171991.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(11971..12188)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(12271..14967)
                     /gene="ppc"
                     /locus_tag="VWX48_001376"
     CDS             complement(12271..14967)
                     /gene="ppc"
                     /locus_tag="VWX48_001376"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU9171992.1"
                     /translation="MSLQKLENYSNKSVVKEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(14987..16216)
                     /locus_tag="VWX48_001377"
     CDS             complement(14987..16216)
                     /locus_tag="VWX48_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9171993.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGSWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(16372..16674)
                     /locus_tag="VWX48_001378"
                     /pseudo
     CDS             complement(16372..16674)
                     /locus_tag="VWX48_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(16779..17027)
                     /locus_tag="VWX48_001379"
     CDS             complement(16779..17027)
                     /locus_tag="VWX48_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEU9171994.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILAYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            complement(17309..17896)
                     /locus_tag="VWX48_001380"
     CDS             complement(17309..17896)
                     /locus_tag="VWX48_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU9171995.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            complement(17975..18403)
                     /locus_tag="VWX48_001381"
     CDS             complement(17975..18403)
                     /locus_tag="VWX48_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9171996.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            complement(18666..18788)
                     /locus_tag="VWX48_001382"
                     /pseudo
     CDS             complement(18666..18788)
                     /locus_tag="VWX48_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18886..19122)
                     /locus_tag="VWX48_001383"
     CDS             complement(18886..19122)
                     /locus_tag="VWX48_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9171997.1"
                     /translation="MKIINGICRYIFDSKGFATIEVEIFLDSGDTGIGAAPRGSTTGR
                     YDIQYNEYYPRGNNFSPIPDGHIEFFRLYNICSG"
     gene            complement(19187..20152)
                     /locus_tag="VWX48_001384"
     CDS             complement(19187..20152)
                     /locus_tag="VWX48_001384"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU9171998.1"
                     /translation="MAIIKKIVVLYGGLSEEREVSENSAKEISKSLLTLGYDVISIDL
                     SQDCSYEIGEIEKSERGLNEQKVEIGSGIIDVCRKVDIVFLATHGGIGENGKLQAIFD
                     VEKIDYTGNSFLSTAISMDKKLSKIVASSVGIKCASNLMVDRIQANDFPIVIKPIRSG
                     SSKGIKIFQNKKQFDIYYKEHPELGSLFVEKYIKGREFSVGILGETVLPVIEIKVKNG
                     FYDYNNKYTVGAAEEVVPAKISEKLTHTLQKSAYKIHKALGFNVYSRTDFIVDEKGDV
                     YFIESNSLPGMTKTSLLPQEAKAAGIDFPNLCERIIELSREIRSQ"
BASE COUNT         6025 a         4444 c         3352 g         6352 t
ORIGIN      
        1 aaaaaagtcc catatgacct ataatgaaaa gcgacaaaac aactcattag aaagaatcat
       61 atggaacaat tacattttat cacaaaatta ctagacatta aagaccctaa tatccagatt
      121 ttagacatca tcaataagga tacacacaag gaaatcatcg ccaaactgga ctacgacgca
      181 ccatcttgtc ctgagtgcgg aaaccaattg aaagaaatat gactttcaaa aaccttctaa
      241 aattccttat cttgaaacga ctggtatgcc tactagaatt ctccttagaa agcgtcgatt
      301 caagtgctat cactgttcaa aaatgatggt tgctgaaact tctatcgtca agaagaatca
      361 ccaaatccct cgtattatca accaaaaaat tgcgcaaaag ttaattgaaa agatttctat
      421 gaccgatatt gcccatcagc tggccatttc aacttcaact gtcattcgaa agctcaatga
      481 cttccacttt gagtgtaatt ttagaaatct gcctgagatt atgtcttggg acgttgaaac
      541 agtctgggga gtgactgttt caatcgggag atggagatga gcttcattgc gcaatatttt
      601 aacaatctca atatcatcac tgttcttgaa ggtagaacac aagctgtcat ccgagatcac
      661 tttcttaaat atgatagagc cgtccgatgt cgcgtcaaaa tcattacgat ggatatgttt
      721 agtccttact atgacttggc taaacagctt cgctttcaaa tttctaggct caggctgaaa
      781 cagtctccca gactgtttca ctcccgaatg ctaaaatcgt tcttgatcgc tttcacattg
      841 tacaacatct tagccgtgct atgagtcgtg tgcgtgttca aatcatgaat cagtttcatc
      901 gaaaatccca tgaatacaag gctatcaagc gctactggaa actcattcaa caggatagcc
      961 gtaaactgag tgataagcga ttttatcgtc ctacttttcg tatgcactta accaataaag
     1021 agattttaaa caagcttttg agctattcag aagacttgaa acaccactat cagctcttcc
     1081 agaataagga accagagaaa tttttcggac ttattgagga caatcttaag caggttcatc
     1141 ctatttttca gactgtcttt aaaacctttc taaagaataa agaaaaaatc gtcaacgctc
     1201 ttcaattacc ttattccaac gcaaaattgg aagcgaccaa taatctcatc aaacttatca
     1261 aacgaaacgc ctttggtttt cggaactttg aaaacttcaa aaaaaggatt tttatcgctc
     1321 tgaacatcaa aaaagaaagg acgaattttg tcctttctcg agcttagccg acttcaaccc
     1381 actacagttg acaaagagcc gggatttttt agcttcttta ctgagatgga ttttcctttt
     1441 tagttcgtgc caatctcaag gcacgatttg gattgagacg attaaatagt tcttccaatt
     1501 tcttttcatt ccaaacgtct gcggcggaaa caaaattacc atccgcatct cggaaagata
     1561 tcggtttatc tcccatacca gtctcctagt ctacaaattc aaactcaaat ttaccaatgc
     1621 ggaccaaatc cccatcttta gctccacgcg cacgaagggc ttcatcaacc cccataccac
     1681 gaagctgacg ggcaaatttc atgacagatt catcacgatc aaagttggtc atattaaaga
     1741 gtttcatgag tttttcacca gaaagtaccc atgtcgcatc gtcatcacga ctaatttcaa
     1801 aggctttttc ttcttcgtca aatccatagt aagcttcttc ttccatatcg gactcgtcgt
     1861 agagcaaaaa ttctggtgtc ttgtctaaca attcagctgt agcatctaaa agtgttgcca
     1921 gaccttgctt ggtcaatcca gaaattggga agatagctgg taactcttca aattcatcat
     1981 aattttcaga caattttttc ttaaattctt caagattttc ctgactctca ggcatgtcca
     2041 tcttattagc tacaataatc tgtggacgct ccatgaggcg aagattgtaa gactccagct
     2101 ctttattgat agctaggtaa tcctcatatg gatcacggcc ttcgctagct gacatatcaa
     2161 tgatgtgaag gataacacgt gtacgctcga tgtgacggag aaactgagtt cccaaaccaa
     2221 caccttgact agccccttca atcaaacctg gcaagtcggc tactgcaaag gattcacctg
     2281 attgggtgcg aaccatacct aaatttggta caatagtggt aaagtggtag gcaccaattt
     2341 taggcttagc tgaggtaata acacttaaaa gtgttgactt ccctacagat gggaatccta
     2401 ctaaaccgac atctgccaag atttttagtt ccaattgtaa ctcacgttcc tgacctggtt
     2461 ctccattttc agagatttcc ggtgcaggat tttttggtgt cgcgaaacga atatttccac
     2521 gtccaccacg accaccgtgg gcaacgataa attcttgccc atgttcaatc aaatctgtta
     2581 aaaccttgcc agtctccgca tcacgaacag tcgtaccttg cggtactcga actctaaggt
     2641 cctcagcacc acgaccatgc atccctttgg tcatcccttt ttcaccagaa tcagccttga
     2701 aatgacgatt gtagcggaaa tccatcaagg tacgtagtcc ttcgtctaca acgaagacca
     2761 cattgcctcc acgaccacca tcaccacccc aagggcctcc attagggaca tatttttcac
     2821 gacgaaaggc aaccatacca tcgccaccat taccagcctt gaccttaatc ttagctgtat
     2881 ctaaaaacat actcattatt tcttctcact ttaaaaaagg gctgggaaat cccagtcact
     2941 aaattttctt gaatctattt tatagattac tgagggcacc aattgcagtt gcaaaaattc
     3001 ccaataaact tgctactagc atgataatca cgataaacaa ggttattttc tcaaacatag
     3061 tttttttacg atttccatta tctccaaatg ccatttttct ctccttcgtt acattctatt
     3121 ttctattatc ttagcatgaa ttgagctagt tttcaatagt cagttgctac tggtgcgata
     3181 atccataaaa taatgtaagc tacaattcca gctccgtaac agcaagtaag aacaccccaa
     3241 atgacttgaa cgatagtcgg atccatatcc agataatggg ccaccccagc acaaacaccc
     3301 gcaatctttt tatcacgacc gcttctcatt aattgttttt ttcatagctg ttcctctttc
     3361 tattcttcat ggtctttcca atagtctctc atactgatca actgtgtttt tgaagccttc
     3421 aacatgcgtc tagatccttt tacaggtaca gcaaccacct gttgcggaag atacaaaact
     3481 gtcttaaaga tacgctgact gaccgtatca tctttagcca aatctttctg gaagttattt
     3541 gaaataatgg catccagata aaactcatgc actcgtttcc caaagttctc agctgaaatc
     3601 tcatacaatt tctctgataa ggtatgctcg ttcatgtctg gtgttgcaat cagggcttcc
     3661 aaaatagcac cagccaaatc atgttctcca tagtacaagg ttccaaacat tttatcactg
     3721 atgaggttgt tcaaataagg atttccatga gcaatgacag gtgttccact ggctaagctt
     3781 tccaagtagg tcaaaccttg cgtttcgctt gtcgatgccg aaatgaagaa atccgccgct
     3841 ttatagtaaa gagccgtctc actaggagca atcatccctg taaagatgac tgagtcttga
     3901 atctctaggt tctgggcttg ctctttgagg tcattcagat aagggccatc cccagctact
     3961 accagtttaa tcttgtcttc ctctttcaga acatcagcaa aggctgctaa aactgcttga
     4021 atattttttt cataggagat tctcgaaaga ctaagcaacg tcttttcacc atcttgaatc
     4081 cctagtttac tacgcagttc tttcaaattt tcctgcttga tttccggacg ctcaaacttg
     4141 gctaattcaa tcccagtagg aatgacccgt ttttcaacct tgaccttata atcagatagc
     4201 aagtcacgga caatctcact aggacaaata accccatcca catcatgcag gaaacctcta
     4261 accagatact tgaccatact cggccggatc aacatcccct tagcaatata atggacatag
     4321 tcttcatact gggtgtgata ggtatggatg actggaattt tcaattcacg cgcaatccaa
     4381 atccccaaca ggccaagaga aaattctgtc tgagtatgga taatatctag ctgatactgt
     4441 ttagcaattt caagtgcctt gctaaaacct cggtaggcaa agcgacgatc cttaaaagca
     4501 aagaaaggaa cacttggaat gcggataatt tgccaatctt cgtagcgatt gacatcctta
     4561 tctgtcgtcg taaagataaa aacagcatgt ccctgctttt caagttctgt tttcaaggtt
     4621 cgaatactgg tcgcaacacc agaaacctga ggaaaatagg tatctgtaaa taaaccaatt
     4681 cgcatagatt acctcacttt ttactttctc cctaaagcgg cttgtttctc ataaaagtcc
     4741 aaccagattt gtaacagatg ctcttcagaa tactctctgg aaatattctt agccttttct
     4801 ttgagatctt ttaaggcagc aggatttgct tgatattcca aaatagcctc tttcatctct
     4861 tctctacccg ctgtcgcccg ataatttccc tccaaaatca ccttatagag atctaaatca
     4921 cgcaacataa taggagcctc acaactcgca gcttctaaaa tagtcatagg aaagagctca
     4981 ttgtaactag gcaacaagaa aagatccgct agagcataca attcgcgcat ccgctctggc
     5041 gatacaatgc ctggaaaaat caaattttta gggggatttt ccataatttt cttatagtgt
     5101 tcataaccat ctgtcatacc accaaaagag aagccaccag cccagataaa ggtaatctga
     5161 ggcaattcct cagccagacg gataaagtca tcaatccctt tacgtttctg aacttgccca
     5221 gcacctacta cgataaactg attgtcacta agaccaagat ctgtgcgcag tctaactacc
     5281 tcttcttgtg gtagaggatg ccatttttcc ttgttgacaa agttaggaat ataggtcact
     5341 ttttcacgtg gaataccagc tgctaccaaa tcctcaataa acataggatt gaccacaacc
     5401 aagtgctcca tccggttgta aaaagaaaat acatagcgtt tcacaattcc ctttaagaaa
     5461 aatggaattt tcaaacttcc ctcaagtgta gctggcaaga aatgcacata gccaatcttt
     5521 ctccctgagc gtttcttttg gaaggttgat aaataatagg gaaaatcaat cgtatgaaag
     5581 tgagtcacat ctgcctcgat tggaagattt tctgtaacaa tcaattggtc cttggcagca
     5641 cggtgaagaa gacgaactaa ttcacggtaa gcacctgaaa ctccctgtcc tgctactttc
     5701 tcacttgaac tcaacatatt gatgcgtaat ttctttttct ccataactac tattatatca
     5761 ttttctttga ataaaatcag caaaagaaag gagagactag aggaaaagag gggaaatttc
     5821 ctcgcttttc caacagtctc tcacatgctt ttatatgttt acttaatgcc tagggcaatg
     5881 cgggcatagc gactcatttt ttcaactgtc caggctggat accagactaa tttaacctca
     5941 gtatccgtta cttctggaac ctctatcata gcatcataaa tctggtctgt caaaaggtct
     6001 gctaagggac aacccatagt tgtcaaagtc atgtcaatct ctgtttgccc tgtgtcaccg
     6061 tcaaaacgaa tctcatagat caaaccaaga ttgacaatat cgattcccaa ctcagggtcg
     6121 atgacttctt ccaaggctgt taaaatccgt gttttgatgt tttcaatttg ctcttctgta
     6181 taagccatat tttcctcact cttagtcttc aataaaatca cgaagcggtt tgctacgact
     6241 tggttggcgt agttttctca aagcctttgc ttcaatctga cggatacgct cacgagttac
     6301 gttaaagact ttccccacat cttcaagtgt gcgcattttt ccatcatcta gtccaaaacg
     6361 tagacgcaga acattttctt cacggtctgt aagagtatct aagatttcat ccaattgctc
     6421 acgcaagacg atacgagtcg tataatccac tggattttca atcacttcat cttcgataaa
     6481 gtctccaagg tggctatcgt cctcttcacc gataggagtt tcaagagata ctggttcttg
     6541 ggcaatcttc aagatttcac gaaccttatc aggtgtcata tccattcgtt cagcaatctg
     6601 ttctggtgtc ggatcttgcc ccaattcttg aaggagattc cgctgttcac gaaccaattt
     6661 attgatagtt tcaaccatgt gaactgggat acggatggta cgagcttggt ctgcaatagc
     6721 acgagtgata gcctgacgaa tccaccaagt tgcataagtt gaaaacttga accctttaga
     6781 atagtcaaac ttgtcaaccg ccttcatcaa gcccatattt ccttcttgaa tcaagtcaag
     6841 gaactgcatg ccacgaccga catagcgttt ggcaatggaa acaaccaaac gaagattggc
     6901 ttccgcaaga cgttgtttgg cttcgatatc gccagcttca acagccagtg ccaactcttt
     6961 ctcctcttca ttggtcaaga gaggaacgac ccctatttct ttcaagtaca tacggacagg
     7021 gtcattgacc ttagcagaag ttgacccaat caagtcctca tcgctgagtt ctggttcttc
     7081 ttcattgcta agaacacgcg cacttggatt tccttcgtta tctgtgatag aaatgcctgc
     7141 atcctgaatc cgttgcaaga gatcttcaat cccatcagcg tccaaggtaa aaggaataac
     7201 cagacttgca ttgatttcat catctgttgc tgtccctttt tgcttatgat tacggataaa
     7261 ttctgctacc tgtacgtcaa atgttgttac ttctttttgt tttgttgcca ttattactcc
     7321 attcttctct tttgggaaat taaacgttcc aattcttcta gggctgtatc tgtatctcct
     7381 acatggctag cttcctgcac cttctttttg attctcatat tgtcctgatt caagagagcc
     7441 ttgtttcgag tcatctctac ttcactaagt tcctgcggcg atatctcagc aggcaaatcc
     7501 tgagctaaaa cttggtacca agctctttca acttcctctg tctgctctgc taaaacttct
     7561 ggaggaagct ttccatactg gccaagcaag tcatataaga cctgaaattc aggtgtagca
     7621 aatgcaaagt cttctcgcaa acggtaatcg ttcaaaacaa gaggggattc catcatccga
     7681 tagagtagat gggcttctgc cctcataata gccgataact gcttggtgac aggcatggtg
     7741 attggcgtcg gtctggaaat tctttccatg cgattctgcc tttgcacctg acgactctca
     7801 ttaacaatct gctcaatctg ggtataatca aaggacgcca gactgtcagc taaaatatga
     7861 atatagctgt tttgagcagc gatggacttt tcttgaacaa tcaagggagc tattttttca
     7921 ataaactcaa tctgagcctg cagattttca ctgttttcag gtttgtactg atgaatgtag
     7981 aactcaatcg gactaatacg agtttttgtt aatagatagg ccaagtcttc tggaccattt
     8041 ttttgtagat actcatcagg atccaagtta tcaggcatgc taacgatttg cacaggcata
     8101 tcaccaattt catccaatgc tttcaatgtc gcggcttgcc cagccttatc tccatcgtaa
     8161 acaagaacca atttcttggt taaccttttc agatgctcaa catgctctcg actcaaggcc
     8221 gttcccatcg acgccacagc attttcgatt ccagcccgat aggctgcaat aacatccatg
     8281 aatccttcca tcaggtaaat ctcactagct tttccagaag atctttttgc cctatccata
     8341 tgatataatt cgtaactttt gttaaaaatt gcagtcgatc gactgttttt atacttagaa
     8401 gtttgtgaat ccgttttttg ccagatacga cctgagaagg caatgacctt tccttggtca
     8461 tttgtcaggg gaaacataat gcgattgtga aaggtgtcta caaattgatt ggcatccgag
     8521 agataaaaca ggcctgaatc cagtaaatcc tcttcacgat actgatcaga caaacgttga
     8581 tagagatagt ttcgttctgg aggtgctaaa ccaatccaaa aatgtttaag cacttcatct
     8641 gtcaaacccc gctgataaag gtaatttctg gcctcttcgc ccatagtcgt tgtcatgaga
     8701 atagcatggt aaaatttggc tgcatcttcg tgcatatcat aaagatcttg gtgaggtgag
     8761 gctggcttct gttcactata aagcggtttt tcaacctcaa tcccgacacg ctgacctaag
     8821 atttggacag cctccataaa ggtaacccct tggtactcct ctatgaactt aaagacatca
     8881 cctgagcgac cacaaccgaa acagtgataa aactgcttat cctctacaac gttgaaagaa
     8941 ggtgtttttt caccatgaaa aggacagagc cctagatagt tccgtcctgc cttttgtaaa
     9001 gaaatcacat ctcctatgac ttccacaatg ttggcattgt ttttgatttc ttcaatgact
     9061 tgtttgtcaa ccatacacaa tacctccatg ttatcatagt ttactttata tagtatactt
     9121 tatttcagaa aaaaagtaaa ccatttcact cattttcctt actttattca aagagttgat
     9181 aataatcaga gattttcatt tttgcttttt cttcttggtt taaatcttgg ataatccgtc
     9241 cttctttcat gacaatcaag cgattgccgt atttgagagc atcttccata tgatgagtaa
     9301 tcataagggc tgttagctga tctttcttaa caaattcatc tgtcaattcc atcaaagcaa
     9361 cactagtctt tggatccagg gcagcagtat gctcatctaa caggagtaat tcaggtcgct
     9421 tcaaggttgc catcaagaga ctcaaagcct gtctttgtcc acctgataag aactcaatcg
     9481 gtgtattcaa gtgtttctca agaccatttc ctactttttc aatggttgcc tgaaattcat
     9541 ccttatagct agtcaagcgt cgtggtaaca atccacgctt ttcaccacga aacttggcga
     9601 ttaaaagatt ttcagcgacc gtcatacggg gagctgtccc catctttgga tcttggaaga
     9661 cacgagacag gtacttggca cgcttctcgg gtgaaaactt agtgagttct tcacctaaaa
     9721 tacggatagt tccactagtt agtgataagg tccctgctat agtgttaaag agggttgatt
     9781 ttccagcacc atttccgccc aaaatcgtga taaagtcccg ttcaaaaatt tctaaggaaa
     9841 catcatttaa aataatcttt tcttcatcaa agccattttt aacgattttg gttgcatttt
     9901 ttaattctac aattgctgtc atttgcttaa cttggctcct ttcaagattg tttgcttaaa
     9961 tgttggaatc atgaggcaga ctgctaaaat caaggcactg tataaacgaa ggtaacttgt
    10021 attaaagcca agtgcgataa ctgcccacac taaaaattga taagcgatag aacctacaac
    10081 gatagtaagc aaacgctctg ccaagctcaa actcttgaaa ataacttctc caataatcaa
    10141 acttgcaagc cccacaacga taaccccgat ccctcgagac acatcggcat aaccttcttg
    10201 ctgagcaatg agggcacctg caagggcaat cacaccattt gataagacca agcccatgag
    10261 ctccatgtgt ccagtatgaa tcccgaaact tctagccata tcaggattat cccctgtagc
    10321 aatataggct tgtccgagtt tagtgtccaa gaaaaagagc atgagagcaa taacaatact
    10381 cacaaagatg agacctgtca agagttgatt caaatccgaa tcaaaaggca aaacatcctg
    10441 aatttgcttg gttccaagca ggcctaaatt cgcacgtccc ataatcaaga gcatgattga
    10501 gtgacaagaa gtcatcacca aaatccctga gagcaaggtt gggatcttcc cttttgtata
    10561 aagaaggcct gctgccattc cagccaaaca acctgctcct acagcaacaa gtgtcgctaa
    10621 aaatgggttc acgcctttgg ttatcaaagt gacagcaaca gctcccccaa gagggaagga
    10681 accttctgtc gtcatatctg gaaagtttaa aatcctaaat gtcataaaga ttcccagacc
    10741 tagaatagcc cagacaaatc cttgagaaat aatggaaaca atcatatttt atttaatcct
    10801 ttctatattc atctttttaa aaaatgggaa gagtctcctc ctccctacct tatttattcg
    10861 atgacttgtc ctgcttcttt gagaacagac tcaggaatag taatacctag ttcttgtgct
    10921 atttttttat tgatgactga cttaccagtt gaaaagacat tgactggggt atcggctggt
    10981 tttgcacctt tcaagacttg cacaatcatt ttacctgttg ccacaccaag gtcatgttgg
    11041 tcaattacaa ctgatgccaa accacctact tctaccatag ctgtcgcact gggataaatt
    11101 ggtttcttag aactttgatt gctagagaca accgttggaa atcctgatgc aatggtgtta
    11161 tcaattggaa cccaaatagc atctaccttg ctagtcataa cagtgacagt tgaggcaatt
    11221 tcatttgttg aaggaactgc aaatgtttcc actgtcagac ctgctttttc agcataagcc
    11281 ttaaattctt cgacctgtgt ttttgaattg tcttcgctac ttgagtaaag agctccgatt
    11341 gttttcacat tcggtgtcag agccttgatg agttcaactt gttgttgagc tggattgtgg
    11401 tcagataccc ctgtaacgtt gccacctggt tttttcaaat ctttaaccaa gttagcacca
    11461 attgggtctg taatagcggc catgataacc ggtaggtctt ttgttgcact agccaaccct
    11521 tgggctgctg gtgttgcgat accaaccaca aggtcattcc catttgcaac caattgttta
    11581 ctcattgtcg caaccttact ttggtcacct tctgagttca taaaatcaat tttaacttga
    11641 tcatctttat atccttcttc tgcaagtcca tcttggatcc ctttataaat caaatcaagg
    11701 gatggatggc tcacaaattg aagcacacca atcttggtta ttttcttctc atccttatta
    11761 ttctgaactt ctgatttatt cattgaagaa taaatcaagc ttcctgctac taagactgct
    11821 aatgcagcaa taattccaat taaacgttta tttttcattc tgtttctcct ttttatttcc
    11881 tttaacatat ttcacttatc taaacaagcg acgccatcgt tttctttcca tactaacctc
    11941 catcaaaaaa atcctcacac aaaaaacttg tgtgaggacg tcgatgcgcg gtaccacctc
    12001 aattataggg aatttcccta tcgctcagtc tcgcaataac gagatgcact gtaaggtgtg
    12061 cttaccgaat ttttataatt tcaaattcta aatagcattc agcccaattt tcatcattgc
    12121 cacttatctg ttttcagcta ccacagactc tctaaaaagt ttgtatgatt acttttctga
    12181 atggttaaat tatatcattt ttaaactact tgtcaatagt ctattagaat ttttttgata
    12241 ttcactttta gcattcactc ttgaaaatta tcaacctgaa ttacgcaatc ctgtcgcaat
    12301 tccgttgatg gtgatatgaa tcaatcgttc ttgatcactg gacaattctc cacgacgttg
    12361 gcgtttaatc aactctaact gaatatagtt gagaatatta aagtaaggca tacggtaatc
    12421 cagactagct tttagatatg gattgtcagc taagagttcg tcatgtcctt caatagccaa
    12481 gataacgttc ttagtaactt gccattcatt taaaatagtc tcatagatgg ccttaacttg
    12541 ctcgtcttca caaagtttag catattcaaa agcaatattc atatttgatt ttgacaaaac
    12601 catatcaaca tttgaaagaa gcgattggaa gaaaggccaa ttttggtaca tatctcgtaa
    12661 gatagcaata ttctctggat ttttattgat aaattccttg aagcttgaac caaccccgta
    12721 ccatccaggg aacataacac gactctgtga ccatgagaat acccaaggga tggcacgcaa
    12781 accaccgatt tcagtaatag tcttacgagc ggctggacga gaaccaatat taaaacttga
    12841 aatagccttg attggacttg actcgaagaa ataatcatag aaatgctcat taccaaagac
    12901 caaatcacgg tagatatcgt aactacggtc cactacttga tccataatgg cttcataacg
    12961 atttggggta ttggtatcgc tcttcttctg agtaatcata cggttaatag ctgccgatac
    13021 tagcatttca aggttatagt aagcggcgtc tttgttaccg tatttattcc caattacttc
    13081 accctgctcc gtcaagcgga tacgatcctt aatagacttg agcggttgag atgtaatggc
    13141 ttcataggtt ggcccaccac cacgaccgac agtaccacca cgaccatgga agaaggtaac
    13201 cttaacgcca aattcatctc caatagcagt caattgttgt tgagccttgt agagggtcca
    13261 acatgatgac aagtaaccgc catctttatt actgtcagag tagccaagca tgatttcttg
    13321 gtagttattt cgtgagtcaa tccatttttt ggcaaggcta agagaaagat attttctcat
    13381 tgtttcctct gaatgatcca agtcttcaat tgtttcaaaa aggggaacaa tctgaacacg
    13441 cgccctttcc gtatccacca gtcctacttc ttttaacaga atagctaatt ctagcatatc
    13501 agaaaggctg gttgcatgtg aaatgatggt ctgacggatg acatcatctc ccaacttatc
    13561 tttcaaaaca cgagccgtct taaaaatagc taattctttt gctaataatt ctgatttttc
    13621 tgcgtgagtc gcagaaagaa ttcggggatc ttcttctaat tctttcaaga gaaggtcaca
    13681 cttttcttct tcgctcaact cgctataacg agaatgaatt cctgctgatt tcaagagttc
    13741 tgccacacag gcttcataga cgctagagtc ttgtcgcata tcaattgacg ctaagtaaaa
    13801 accaaatatc tctactgcct gcaataattc cacaaaatca cctgaaatca aggactcgcc
    13861 cttattttct agtagagaat ctcgaatggc aatcaaatcc ttgtagaaat cattggcggt
    13921 ttcataacga gtcccaactt cttcatcctc aatcagatag gttttagttg cctgaatttt
    13981 tgattgaata tcaaacaagg cacgacggta aagctctttt tcgcggtaaa tcgagttatc
    14041 cttggattga cgagccattt ctctgacttg cttgctgacg ttgacaatgc tagttgaaag
    14101 agaaaattca cgataaagtt ggtaaatctt tttatcatag tagttcatga tgacttcaca
    14161 ctgagtgagt gcagactgct tcaaggtctt tgctgtaaca aatggatttc catcacggtc
    14221 accacctatc cacataccca tggtgattgg tttagcctgt tttaaattca gaccatgcgc
    14281 ttgcgctaag cgcttatact ccgtcgtcaa atgaggtaca gctttcaaaa aggagctgtt
    14341 ataatattcc atagcattcg tgatttcgtt agtcactttt aattttttct cacgaatcat
    14401 gtctgtctgc atgataattt cgatgtaacg acgcaaatca ttgtaccatt tatctttatt
    14461 gatcaacccc aacttaacat cacggtattt acgcaaaaga ctatgaatat gatttgttaa
    14521 atccaacata cttttgcgtt gcacttgtgt tggatgggct gtcaaaacag ggacaacatt
    14581 caagtgttct aggatctcaa cggcattttc cttttctgct accaatttaa tcgttgtaga
    14641 taatttacct aaatagtcct gatcaatatt attttgatga ttgatttcat aagctaaatc
    14701 cacatcctct gaaatattaa tcaaaagagg taagatagag aaatagcgtg aaatatagac
    14761 catttcatca tttgataagc tagtcactag acggtttaga ccttgataat cttcctgcgt
    14821 tgataattct ttcaactgta ttattttttc aaaggtctct ggggcaagca tatttttagt
    14881 aatatcttcc agtaattctg ttagaatcaa gacttcttct ttcacaacac ttttattact
    14941 ataattttct aatttttgaa gagacataaa ctatcctttc tttatcctac ttcaacagaa
    15001 ggttcattgg ttgattttcc aattctcggt acaacttagc gcgtttttca ctggcatcaa
    15061 tatttaagac aaaggctact gccactgata agactagaag actatttcca ccctgggata
    15121 agaaggggaa agtcactcct gtagatggaa tcaagcccga aatccctccg atattgacaa
    15181 atacctgaac caacatcatc cctccgacac cgagtgcaac catggcattg aaaggattct
    15241 ccgctcggat accgaccaag ataatccgca aaatcatgaa aaacaagaga gctaaaataa
    15301 gactggcacc aacaaagcca aattcttcaa tcacgataga aaagacaaag tctgtatgag
    15361 cttctggcaa ataacctcgt ttttcaatcg agtttccaag acctagacca aaccaactgc
    15421 cattgaccat ggcaaaataa gaattagcta actggtgacc tgcatcagca cgatcggcaa
    15481 aaggattaaa aaaggcacta aagcgcttgg ctacatagcc aaatactgga atttttgaaa
    15541 aggtctcaac accgattagg ctgatagtgg tcaagacaaa gacagaagcg gcagatacga
    15601 gcgccagaat ggttgaaaac cagcgataag cgattccact aactgtatac ataatcaagg
    15661 aaaccaagac taaaatagtc gcatttccta aatcagggaa aattcccaaa cttccaatca
    15721 gaactaggag aacgaatcgc caatcattaa aagcacgggg aagccattga ttttgagtca
    15781 aaacttgaaa atcataagta gctatttctt cttgctgttt ggagaatcgg tgagctaaat
    15841 accaaataat aatgattttt aagtactcag ctggctgaat agttactcct gcaaccgaaa
    15901 tccaaccgta tgccccgttt acggaaatac caataaaacg agccaagaac aataaaagca
    15961 tttctattaa tataactaaa atgattagtc gctcatttct caaaaaatct agtctcaatt
    16021 tataaattaa ggcaatcagt atcaaactaa caatccaaaa gattccttgg tttcgaacca
    16081 actgcaaggc actcttgcct tcttcaatta aaatagcact ggtggtcgaa tagaccacaa
    16141 tcaagcccaa aatagataaa agcaagtagg gaatcaagat ggaataattt aataagtgcc
    16201 tcttactaat cttcatagca tcaccactct actaggatac agataaatct gttccaaatt
    16261 ccgttttatt ttctagtttt gattgctatt ataccatttt ttcagaaaga aaaaaactct
    16321 taccttacaa tccttcgaat tttactgttt ttacagaatt aaggcagaat ttgaaatcgt
    16381 aaaaccattt tgaataagag ttgcttcaac ccattgactc cgacggatta agttgctttc
    16441 gtgaatgcca aaatcagccg caatttgttc ataagtgcgc tattctcgca tgtattgaat
    16501 agttaccata aggagatcgt ctaggattaa tttgcttttt cgtccacctt ttgcgcgttt
    16561 acgttgataa gctgttttta acacagctaa catctcttca aaagtcgtgc gctgaacacc
    16621 tacaaggatc ttgaaacggc tatcgcttaa ttgtttactt gcttcatcat ccatagtttt
    16681 attgtattgt atttttgttt cgcaggaagt ctattattcc tttcgttcca aggtttttac
    16741 gcttttagca acaagcttac acactgagcg tttcggactt accatatcat ttcgttggag
    16801 attttatcat caatttttag attaaaaaaa atttcccaat cttcacaaac ttctgtagca
    16861 ggaattgtat gaatctttct aagtatcttt cctgcttcta caccatatgt gtattgttgg
    16921 ttttctgaat aagctaaaat gctatctatt gcatctcttc cgtctatcca ttcgtgtaaa
    16981 gaatgtactt cgtcatcgca gagttcaatg ctaattggtt tacacatcgg aactccaaga
    17041 gaagctactt tctccatcat atcaaattca aattttttta taatctaact tcgacttatc
    17101 agaaacacgc aagaaatatt tttactgatt ttgatctgtc acacaatatt ttttatcatc
    17161 tgaccagcct ttatttatgg ctatcttact actaaaatcc atcaagcaca ctccgattca
    17221 ctttacaaca ctttttgcag ttttcactag taacctatcc agttcgtcta cacttttatt
    17281 tcctagatcc atttttacat tatgaaagtt aatcaatttt ctctatgatg tttccaagtt
    17341 tatccaatac aagacaagaa tgatcattta gtggaattat gggaacatta acgagttctt
    17401 cagctctatc cttatttgct ttatcattcc aggaatcata atggacacta attaaaaact
    17461 gactaaagag tcctaatcca ttttttatct ttatctgatg atctgaatta tcattaggtg
    17521 agacatagac tttttctcct aatagtaggg ctcctgcaga aaatcctata atttttgcct
    17581 ctttattaag catatgatcg atataacttt tgaactcctg attaacataa gtagcaatat
    17641 atttttccgt atttccacca ccgatgataa ttatgtcagc atctagatag ctatcaagat
    17701 caatctgctc agtgtccagg agcaagtaat caatgtttag attaggaaat tgactttgaa
    17761 aaacttccgt gtactttttc atgtacggtt cccaattttc tcgaaaaact gtaaaaatga
    17821 taattctttt aatcttggtt gataatacaa ttttatcaac aatactatat ttcttcattg
    17881 ggggattccc acccatcaaa aaaatttgtt ctttcaagtt aacacacttt ctaaagatac
    17941 ataaagttta aacaagttta ttcacgtttc taaattataa ttttttctta aaatgaataa
    18001 ttctatttgc ctcctgaaat ccaatattga gatgaaatct tatagaatcc gtattcgtta
    18061 aagtacagtc acttgcaaat tccttacatc ctttattttt cgcccattcc tcacattttg
    18121 tacagagatt tttagcaata tcctttaaac gatattcctc gtcaacaata atcccttcta
    18181 agaatccaac aggactatat ttacaacctt caacataatc aaatctgagt gaacatagtg
    18241 ctagacctac aattgtgtca ccttcaactt cagtaaagat tgcagtattt ttgccattcg
    18301 tatatttttt tacttcatca atagcttctt tatcggtcaa ttggggccat aattgtttca
    18361 ttagtttagc cgtttttata aaatcttttg ttattccatc catattgatg ttcctccgca
    18421 aattacaagt aaatgtttcg aatcatgctg atactttgtt actcattgat tgataccaat
    18481 accatcccct tctacttttc gactgtctca gatcggaaga gcagagccac gcactcagcg
    18541 gttcggactt accttatcat ttcgtcggtt ttcctcctca ttctacgagt cctaccgcat
    18601 gggagatcat ttacttctac ttcgctgatg cctcagcttg tacaagcagt gatactgcct
    18661 caacatggtg cgtcgtagtc cagtttggcg atgatttcct tgtgtgtatc cttattgatg
    18721 atatctagaa tcttgatgtt tgggtcttta atatcgagca gttttgtgat aaaatgtaat
    18781 tgttccatat gattctttct aatgagttgt tttgtcgctt ttcattatag gtcatatggg
    18841 actttttttc tacacaaaat aggctccata atatccatag gggatttacc cactacaaat
    18901 attatagagc ctgaaaaatt ctatatgtcc atctggtatt ggactaaagt tatttcctct
    18961 aggataatac tcattatatt gaatatcata acgcccagtt gtagaccctc gtggagcagc
    19021 accaattcca gtatctccac tatcaagaaa aatctctact tcaattgttg cgaacccttt
    19081 tgagtcaaag atatatctgc aaataccatt aattattttc ataggcttcc actttctttt
    19141 ttatcattga aaattacttt tttataaatg tcgtcgattt tattttctat tgagatctaa
    19201 tttccctact cagctcaata atacgttcac ataggtttgg gaaatctata ccagctgctt
    19261 tcgcttcctg tggtaataaa cttgttttag tcatacctgg taaactattt gattcaataa
    19321 aatatacatc ccccttctca tctacaataa aatcagtacg tgaataaaca ttaaatccaa
    19381 gagccttatg tattttatat gcggattttt gtaaggtatg agttaacttt tcagatattt
    19441 ttgcgggaac gacttcttca gctgcaccaa cagtgtactt gttattataa tcataaaaac
    19501 cattttttac ttttatttca ataaccggta aaacagtttc acctaaaata cctaccgaaa
    19561 attctctccc cttaatatac ttttctacaa ataatgaacc aagttcagga tgctctttat
    19621 aataaatgtc aaattgtttt ttattttgaa atatcttaat acctttactt gaaccacttc
    19681 taattggctt tataacaata ggaaaatcat ttgcctgaat tctatcaacc atcaagttcg
    19741 aagcacattt tattccaaca gaactagcca ctatttttga taatttttta tccatgctaa
    19801 tagctgtact aagaaacgaa tttcctgtat agtctatttt ttctacatca aaaatagcct
    19861 gtagtttccc attctcacct attccaccat gagttgctaa gaaaactata tcaacctttc
    19921 tacaaacatc aataataccc gaaccaatct caactttttg ttcatttaat ccgcgctcac
    19981 ttttttcaat ttctcctatc tcgtacgaac agtcttgaga taaatctata gaaatcacat
    20041 cataccccaa tgttaataga cttttactaa tctcctttgc agaattttct gacacctctc
    20101 tctcttcgct aaggccacca tatagtacaa caattttttt aataatagcc attcacttaa
    20161 cctccttatt aga
//
LOCUS       DAVKAU010000033        19724 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVKAU010000033 DAVKAU010000000
VERSION     DAVKAU010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19724
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.033"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            180..2078
                     /gene="glgB"
                     /locus_tag="VWX48_001385"
     CDS             180..2078
                     /gene="glgB"
                     /locus_tag="VWX48_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU9171999.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTN"
     gene            2098..3240
                     /locus_tag="VWX48_001386"
     CDS             2098..3240
                     /locus_tag="VWX48_001386"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU9172000.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3230..4369
                     /gene="glgD"
                     /locus_tag="VWX48_001387"
     CDS             3230..4369
                     /gene="glgD"
                     /locus_tag="VWX48_001387"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU9172001.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4366..5799
                     /gene="glgA"
                     /locus_tag="VWX48_001388"
     CDS             4366..5799
                     /gene="glgA"
                     /locus_tag="VWX48_001388"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU9172002.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLIKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5858..6229
                     /locus_tag="VWX48_001389"
     CDS             5858..6229
                     /locus_tag="VWX48_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU9172003.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6174..6503
                     /locus_tag="VWX48_001390"
     CDS             6174..6503
                     /locus_tag="VWX48_001390"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU9172004.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            6512..7627
                     /locus_tag="VWX48_001391"
     CDS             6512..7627
                     /locus_tag="VWX48_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU9172005.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFNKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(7624..8070)
                     /locus_tag="VWX48_001392"
     CDS             complement(7624..8070)
                     /locus_tag="VWX48_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU9172006.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8234..9538
                     /gene="eno"
                     /locus_tag="VWX48_001393"
     CDS             8234..9538
                     /gene="eno"
                     /locus_tag="VWX48_001393"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU9172007.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9676..10122)
                     /locus_tag="VWX48_001394"
     CDS             complement(9676..10122)
                     /locus_tag="VWX48_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9172008.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(10022..10234)
                     /locus_tag="VWX48_001395"
                     /pseudo
     CDS             complement(10022..10234)
                     /locus_tag="VWX48_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10332..10850)
                     /locus_tag="VWX48_001396"
                     /pseudo
     CDS             complement(10332..10850)
                     /locus_tag="VWX48_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10904..11079
                     /locus_tag="VWX48_001397"
                     /pseudo
     CDS             10904..11079
                     /locus_tag="VWX48_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            11279..14554
                     /gene="rexB"
                     /locus_tag="VWX48_001398"
     CDS             11279..14554
                     /gene="rexB"
                     /locus_tag="VWX48_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU9172009.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADSKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            14551..18201
                     /gene="addA"
                     /locus_tag="VWX48_001399"
     CDS             14551..18201
                     /gene="addA"
                     /locus_tag="VWX48_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU9172010.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVELKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNSQKWL
                     SDSFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQSVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGRLILLKENFRSSSEVLSTTNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEAQVVKV"
     gene            18416..19594
                     /locus_tag="VWX48_001400"
     CDS             18416..19594
                     /locus_tag="VWX48_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172011.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         5974 a         3775 c         4254 g         5721 t
ORIGIN      
        1 tagaaaaaga aaggcgtttt cgcaattttt tgaaaaaata ttgatttaca attgaacgag
       61 taagtgaact tgttgtagat tttcaaaata attaaagaag tatagtaatt tacttgaatc
      121 ttctctaaaa aggtagtata ataaaaacat agaaaacgct tacaggagaa ggggagtata
      181 tggataatag agaagcatta aaaaccttta tgacgggtga aaatttttat ctccaacatt
      241 atctaggagc acatagggaa gaactaaatg gagagcatgg ctataccttc cgtgtttggg
      301 cacctaatgc tcaggctgtt cacttggttg gtgattttac caattggatt gaaaatcaga
      361 ttccaatggt aagaaatgac tttggggtct gggaagtctt taccaatatg gctcaagaag
      421 ggcatattta caaatatcat gtcacacgtc aaaatggtca tcaactgatg aagattgacc
      481 cttttgctgt caggtatgag gctcgtccag gaacaggggc aatcttaaca gagcttcctg
      541 agaagaaatg gaaggatgga ctttggctgg cacgaagaaa acgttggggc tttgaagagc
      601 gtcctgtcaa tatttatgaa gttcacgctg gatcatggaa aagaaattct gatggcagtc
      661 cttatagttt tgcccagctc aaggatgaac tcattcctta tctcgttgaa atgaactata
      721 ctcatattga gtttatgccc ttgatgtccc atcctttggg cttgagttgg gggtatcagc
      781 ttatgggtta cttcgcttta gagcatgctt atggcagacc agaggagttt caagattttg
      841 tcgaggagtg tcatacccat aatattgggg ttattgtgga ctgggtacca ggtcacttta
      901 ccatcaacga tgatgcctta gcctattatg atgggacacc gacttttgaa taccaagacc
      961 ataataaggc tcataaccat ggttggggtg cccttaattt tgaccttgga aaaaatgaag
     1021 tccagtcctt cttaatttct tgcattaagc attggattga tgtctatcat ttggatggta
     1081 ttcgtgtgga tgctgttagc aacatgctct atttggacta tgatgatgct ccatggacac
     1141 ctaataaaga tggcggaaat ctcaactatg aaggttatta ttttcttcaa cgcttgaatg
     1201 aagttattaa gttagaatat ccagatgtga tgatgattgc agaagaaagt tcgtctgcaa
     1261 ccaagattac gggaatgaaa gagattggtg gtctaggatt tgactacaaa tggaacatgg
     1321 gctggatgaa tgatatcctc cgtttctacg aagaagatcc gatttatcgt aaatatgact
     1381 ttaacctggt gactttcagc tttatgtatg ttttcaagga gaattatctc ttgccattct
     1441 cgcacgatga agtggttcat ggcaagaaga gtatgatgca taagatgtgg ggagatcgtt
     1501 acaatcaatt tgcaggcttg cgcaatctct atacgtacca aatttgtcac cctggtaaga
     1561 aattgctctt catgggtagc gaatacggtc aattcctaga atggaaatct gaagaacagt
     1621 tggaatggtc taacctagaa gacccaatga atgctaagat gaagtatttc gcttctcagc
     1681 taaaccagtt ttacaaagat catcgctgtc tgtgggaaat tgataccagc tatgatggta
     1741 ttgaaatcat tgatgcggat aatcgagacc agagtgttct ttcctttatt cgtaagggta
     1801 aaaagggaga aatgttagtc tgtatcttta acatggtacc tgttgagcgg aaagatttta
     1861 caatcggact acccgttgca ggaatttacg aagaagtatg gaatactgag ttggaagagt
     1921 ggggaggtgt ttggaaagaa cataatcaaa ctgttcaaac gcaagaagga ctatggaaag
     1981 attatgagca gaccttaacc tttactctac cggctatggg agcaagtgta tggaaaatca
     2041 aacgtcgctt gaaatctact aaaaccgtca caaattaaaa ccaaaaagga gtagaaaatg
     2101 aaaaatgaaa tgttagcttt gattcttgct ggtgggcaag gaactcgtct cggtaaactc
     2161 actcaaagca tcgcaaaacc agctgtgcaa tttggtgggc gctaccgtat cattgacttt
     2221 gccctatcaa actgtgccaa ctcagggatt cataatgttg gggtcgttac acagtatcaa
     2281 ccacttgctc tcaacaacca tattgggaat ggttcaagct ggggactaga cggtattaat
     2341 tcaggcgtct ctattcttca accttattct gcaagtgaag gaaatcgttg gtttgaggga
     2401 actagtcacg ctatttacca aaatatcgac tatatcgaca gtgtcaatcc tgagtatgtc
     2461 ttgattttgt ctggggacca catctacaaa atggactatg atgatatgct ccagtctcat
     2521 aaggataata atgccagctt gacagtagca gttttagacg tccctcttaa agaagcaagc
     2581 cgttttggta tcatgaacac agatgctaac aatcgtattg ttgaatttga agaaaaacca
     2641 gctcaaccta aatctacaaa agcttctatg ggaatctaca tttttgattg gcaacgcctt
     2701 cgtaatatgt tagtcgctgc tgaaaagagc aaggttggca tgtcagactt tggtaaaaat
     2761 gtcattccaa attaccttga gtcaggtgaa agtgtttatg cttacgaatt tagtggttat
     2821 tggaaagatg ttggtactat tgagtcactt tgggaagcga acatggagta tatttctcca
     2881 gaaaatgcct tggatagtcg taaccgtcaa tggaagattt actcaagaaa cttgatttca
     2941 ccaccaaact tcctcggggc aaatgctcat gtggaagact cattagttgt agacggatgt
     3001 ttcgttgatg gaactgttaa acattctatc ctttcaacag gcgcgcaagt tcgcgaagga
     3061 gcggaagtcc ttgattcagt tatcatgagt ggagctatca ttggtcaagg agctaagatt
     3121 aaacgtgcca ttattggtga aggtgcgatt atttctgatg gtgtcgaaat tgatggaaca
     3181 gatgaagtac aagttgtagg atataatgaa gtagtggggg tagcaacaga tgaagattga
     3241 taaatattct gccattttag gaaatacagt tggttttcac aatatgtcga cattgacgga
     3301 ccaccgtcca gtagcaagtt tgccatttgg tgggaaatat cgtttgattg acttcccgct
     3361 ttcaagcctt gctaatgcag gtgttcgtag tgtctttggt attttccagc aggataatat
     3421 cagctcagta tttgaccata ttcgttcagg acgcgagtgg ggcttatcaa cccttcttag
     3481 tcattactat ctaggaattt acaatacccg tgtagaaagt agtacagttg gaaaagaata
     3541 ctaccaacag cttcttactt atttgaaacg ttctggctca aaccaaacgg ttgccctcaa
     3601 ctgcgatgtt cttattaaca ttgatttgaa ccaagttttc cacctacata gtacaacaaa
     3661 agagcctatc actgtagttt ataaaaaact agctaagaaa gatatttcag aagtaaatgc
     3721 aatcttggat gtagatgaaa cagaccatgt tctttctcat aaactctttg atagcaagtc
     3781 aacagctgaa acgttcaata tgtctacaga tatctttgtc gttgatacac cttggttgat
     3841 tgaacacttg gaagaagaag ctaaaaaaga acatccaaag aaattgcgct atgttttacg
     3901 ggatttggct gtaaaagagg gagctttcgc ctacgagtac acgggctatc tagccaatat
     3961 tcactctgtt aaatcttatt atcaagcgaa tatcgatatg cttgaatcac aaaaattcta
     4021 ttctcttttc tcaccaaacc aaaagattta tacaaaggtc aaaaacgaag agccaactta
     4081 ctatgctaat acatctaagg taagcacttc tcagtttgcc tctggtagta ttattgaagg
     4141 tcaagtagct aattctgttc tatcacgtaa tattcatgtc cataaggata gcttggttaa
     4201 agatagcctg ctcttccctc gtgttgttat tggagaaggg gctcaggtcg aatatgctat
     4261 cttggacaaa ggggttgaag ttgagcctgg tgttgtgatt cgaggaactg cagaacatcc
     4321 agttgtggtt aagaaaggtg ctaaagtaac agaggatatt cattcatgaa aattttattt
     4381 gtagcagcag agggtgcacc cttttcaaaa acaggtggtt tgggagacgt cattggcgct
     4441 cttccaaaat cactgataaa agctgggcac gaagttgcag tgattttacc ctactatgat
     4501 atggtagagg ctaaatttgg aaatcagatt gaagatgtac ttcattttga ggtgagcgtt
     4561 ggttggcgca gacagtattg tggaattaag aaaacagtat taaatggtgt aaccttctac
     4621 tttattgaca atcaatatta tttcttccgt ggtcatgttt acggtgattt tgatgacgga
     4681 gaacgctttg cctttttcca actggctgcc attgaggcta tggaaaggat tgactttatt
     4741 cctgatcttc tccatgttca tgactaccat acagctatga ttcctttctt gttgaaggaa
     4801 aaataccgtt ggattcaagc ctatgaggac attgaaacag ttttaaccat tcataattta
     4861 gaattccaag gacaattttc agaaggaatg ttgggtgatt tgtttggagt tggctttgaa
     4921 cgttacgctg atggcaccct tcgatggaac aactgtctga actggatgaa ggcaggtatt
     4981 ctctatgcga accgtgtttc aaccgtttca cctagctatg ctcatgaaat tatgactagt
     5041 cagtttggat gtaatttgga tcagattctt aaaatggagt ctggtaaagt atctggtatc
     5101 gtgaatggga ttgatgctga tctttataat cctcagacgg atgctctttt agactatcat
     5161 ttcaatcagg aagatttgtc tgggaaagcc aaaaataagg caaaattgca agaaagagtt
     5221 ggcttgcctg ttagagcaga cgttccactg gtgggaattg tttctcgttt gacacgtcaa
     5281 aaaggttttg atgtggtggt cgaaagtctt caccatatct tgcaagaaga tgttcagatt
     5341 gttcttttgg gaactggcga tccagccttt gaaggagctt tctcatggtt tgctcagatt
     5401 tacccagaca agctatcagc aaatatcact tttgatgtca aacttgctca ggaaatctac
     5461 gctgcttgtg acctcttcct catgccaagt cgttttgaac cgtgtggctt gtctcaaatg
     5521 atggctatgc gttatggaac cttgccattg gtccatgaag ttggaggctt gcgagataca
     5581 gttcgcgctt tcaatccaat cgaaggaagc ggtactggct ttagctttga caatctatct
     5641 ccttattggt taaattggac tttccaaaca gcattggact tgtatagaaa ccatccagac
     5701 atttggagaa acctacaaaa acaagctatg gagagtgact tctcatggga tacagcctgc
     5761 aagtcatacc ttgacttgta ccatagttta gttaattaat agataaaatc gtatgatgac
     5821 ttcatacgat ttttaggctg tttagagagg agaactgatg tctcaagtaa aaggcttgtg
     5881 tgttttggat gtagatggaa ccttaatcct agaagaagtg attgatcttt tagggagaga
     5941 ggcaggtcat gaggcggaaa tttcgcagat tacaagtcga gcaatgcgag gagagttggt
     6001 ctttgaaagc agtttaagaa aaagagtgtc cttgttggaa ggtcttccta ttttggtctt
     6061 tgataacgtc ttcaactcaa ttcatctatc gctaaatgtc ccagagttca tctctattct
     6121 ccaaaagaat ggcatcctag ttggtctggt gtctggtgga tttacaccaa tagttggaga
     6181 gattagcaaa atcccttggt attgcctatt tcactgccaa ccagcttgaa gtcaaagaag
     6241 gtcttttaac aggaaaatta gttggacaaa ttataagtcc ccaggtcaaa aaagaaactc
     6301 tggaaaaatg gagaaagaaa ctaaaacttt ctaaagaaag aacggtggca atcggtgatg
     6361 gggtcaataa tctattaatg ttgaagtcgg cggagttagg aatcgccttt tgttccaaag
     6421 aaatgctcaa aaaagaaata ccacatcatg ttgacaagag ggatttttta gaagttcttc
     6481 ctttgattga ctgtttagaa tgagggaaaa tatgaagatt gtaattgcac cggattcgtt
     6541 taaggaaagc ttgacagctc aacaggtagc tgaagcaata aaaagaggct tccaacaatc
     6601 gatagcagat gtagaatgtc tcctctgccc tgttggtgat gggggagaag gtactgtaga
     6661 tgctatccga cattctcttg acctaaaaga aaaatggatc caagtgacag acccttttgg
     6721 acaaaaagaa gccatgcgct attttcaaaa aggggaactg gcactatttg aagtagctga
     6781 cttggttggt cttggaaaaa ttccgctaga gaaacgaaat ccacttcaaa tccaaacttg
     6841 tggtattgga gagttgattc tccatctcat ttctaaaggg attaaagata tttatatcgg
     6901 tgttggtggc acggccagta atgatggagg actggggatt gctgctggtt taggttatca
     6961 attttatgat agggatggaa atgtcttgcc tgcttccgat caatccttat taaacttagc
     7021 ttctgtttca acagaaaatt gctataaaat tcctgaaggt gttcaaattc atattctagc
     7081 agatgtcgtg agtcccttat gtggtcatca aggtgcgact tacacttttg gcaatcaaaa
     7141 aggtctacat ccgactatgt ttgcagtcgt agatcaggcg atccaagatt tttatgaaaa
     7201 attctcacct gcaacattag aaattaaagg agcaggagca ggtggaggcc ttgctggtgg
     7261 tttgtgtgcc tttgctcagg caagtatcgt gtctggaatt gatacctgct tggacttaat
     7321 caactttaat aagaaagttt cagatgctga cttggttgtt gttggagaag gaaggcttga
     7381 tagtcaaagc tttgctggga aagcgcctat aggtgttgca aaaagaaccc ctgttggagt
     7441 tcctgttatt gctatttgcg gtagtcttgc tgaagattta cctcccctac catttgaaaa
     7501 tatccaagct gtcttttcta ttttggagaa aagtgaacct ttagaagata gtttgaaaaa
     7561 tgccagtctc tatctggagc gcacggctgc caatattggg cacttattaa atatgtgcaa
     7621 gatttagcta aaccatttct tccataagga tgttttggct ggttcttcct ttttaacttc
     7681 ccaaagtttt ggaaaagcaa gtcgaaggtc tttttcttct acttgaactg gtgcattgct
     7741 atgaataacc aggccaaaag gagaagtaat atgctcttca gatactatgg tggcttgact
     7801 atcagtttct tttgcttctt ttaagtagaa aacttgctta tcaaattcga tagttggtga
     7861 aatcttcaca aatagtggct ctgctttttc ctgaaggttt tctaaaataa ataaaaagcc
     7921 tttttctaac tgagggctat ttgctgtgtc aatatctaca tatccaagaa ctctttcctc
     7981 aaaagtacca agatagcgtc tttgctcatc cggatttatt tttaacccac catgagcttt
     8041 ttcaagtaat tgttttgata aatctgtcat gaaaacagta tatcataaaa gttagcataa
     8101 aacagacaaa agaaagcgat tactttataa agttaaggaa aagttgcaca aagataacgt
     8161 tttttcttga aaaaggaggg gttttaaggt attatagagg tgtaaaaaat ttaactcata
     8221 aggagagtaa aaaatgtcaa ttattactga tgtttacgct cgcgaagtcc tagactcacg
     8281 cggtaaccca acacttgaag tagaagttta cactgaatca ggtgctttcg gacgtggtat
     8341 ggttccatca ggagcttcta ctggtgaaca cgaagcagtt gaacttcgcg acggtgacaa
     8401 atctcgttac ggtggtcttg gtacacaaaa agctgttgac aacgtaaaca acatcattgc
     8461 tgaagctatc attggctacg atgtacgtga tcaacaagct attgaccgtg ctatgatcgc
     8521 acttgacggt actcctaaca aaggtaaatt gggtgcgaat gcaatcctcg gtgtgtctat
     8581 cgctgtagct cgtgctgctg ctgactacct tgaaatccca ctttacagct accttggtgg
     8641 attcaacact aaagttcttc caactccaat gatgaacatc atcaacggtg gttctcactc
     8701 tgacgctcca atcgctttcc aagagttcat gatcttgcca gttggtgcgc caacatttaa
     8761 agaagccctt cgttacggtg ctgaaatctt ccacgctctt aagaaaatcc ttaaatcacg
     8821 tggtttggaa actgccgtag gtgacgaagg tggattcgct cctcgtttcg aaggaactga
     8881 agatggtgtt gaaactatcc ttgctgcgat tgaagctgct ggatatgtac caggtaaaga
     8941 cgtatttatc ggatttgact gtgcttcatc agaattctac gataaagaac gtaaagttta
     9001 cgactacact aaatttgaag gtgaaggtgc tgctgttcgt acatctgcag aacaaatcga
     9061 ctaccttgaa gaattggtta acaaataccc aatcatcact attgaagatg gtatggatga
     9121 aaacgactgg gatggttgga aagctcttac tgaacgtctt ggtaagaaag tacaacttgt
     9181 tggtgacgac ttcttcgtaa caaacactga ctaccttgca cgtggtatcc aagaaggtgc
     9241 tgctaactca atccttatca aagttaacca aatcggtact cttactgaaa cttttgaagc
     9301 tatcgaaatg gctaaagaag ctggttacac tgctgttgta tcacaccgtt caggtgaaac
     9361 tgaagattca acaatcgctg atatcgcagt tgcaactaac gcaggacaaa tcaagactgg
     9421 ttcactttca cgtacagacc gtatcgctaa atacaaccaa ttgcttcgta tcgaagacca
     9481 acttggtgaa gtagctgaat atcgtggatt gaaatcattc tacaacctta aaaaataaaa
     9541 tagttcagtg aactatttta tcccgaacca tgaaattcaa aagttcggcc gttgatttaa
     9601 caacgtttct agcccctcgg attttatccg aagggctatt tttgtattta gaggacaaaa
     9661 aagggacaaa actttttaaa aaatcttttt cataacttta tccagtacat tgattgcttc
     9721 atctttcatg ttctttgtga cgtgagtgta gatggaagta gtgacttcag agtcggaatg
     9781 accaaccctg tccgtgattg tttttaaagg aattttattt tctgataaga tgctaatagt
     9841 ggtgtgtctg aagatgtgag gggacagatg tttgggaatt ggttttttaa ggcgttcgtt
     9901 tgctcgctgg agagacttgc tcaagataga actatgaact ggttttcctg tattggtaac
     9961 aaaaatacgg tcgcttttgt gccaattctt atcggttgtt tcgcttagac aatttatata
    10021 gtcaattgaa acaagaacaa gacaaaagag cctcataaaa ggtattgcaa cttggtaata
    10081 cccttttgag gtgctttttg atatgagccc atgttttctc aataagattg tactcaggcg
    10141 agtagggagg aagaggtaaa agtttatgcc caaactcttc acacaagagt tctagcttcc
    10201 ccattctatg gaatcttgca ttgtccatta atatagtaga ttgaaactag aatagtacac
    10261 ctctacttct aaaacattgt tagaattcga ttttactgtc ctgatcgatt tgtcctgttc
    10321 ttatttcatt tcactataat aaccgatggt gtggttaatg ttggtaagag aaacttctga
    10381 aaccatactt caaaaaagtc gctcgtcatc atctcttcgt aagtcattgg agcgattaat
    10441 tcaccatttg ttagacctgt gctaggtgct ttaaactatt aaaattctta agaaataagg
    10501 ctactttttc tgggtcttgt tcatagtagg tgtggttctt tttttcgagt gtagcccata
    10561 gctttgagtg catagtggat ggtagttgga tgacagccaa attcagaagc tatttcagtc
    10621 aaataagcgt ctggattatc agtaagatag tttttaagtc tatctctatc aacttttctt
    10681 ggttttgttc cttttacttg gtggtttagc tctcctgttt tctcttttag ctttaaccag
    10741 ccataaatgg tattacgtga gatttggaaa acgtgtgatg cttctgttat actacctgtt
    10801 cgctcacaat aagagagaac ttttttacga aaatctattg aatatgccat aagaagatta
    10861 tacctcattg tgtactattt ttggttcatt ttactatagt tcaatcattc tatcaagaat
    10921 attgaatata taaaggcacg taatattaaa acttcttctg attctgatat cgaattagag
    10981 tccgatgttg atggcgataa atcagacaat ctacccgtcg acattaagat actgggacaa
    11041 cacattgaag tgtattccgt acctaagaaa caatcataaa actcaaagcc ttgttaccga
    11101 ggctttttta ttatgtgatt ttcagtagcc agacttattc tatctaatac aagtaaagct
    11161 aagtatttaa gatttagcag atgatgaaga aaagaaagga tggcctaaat attttaacag
    11221 atttacgagg ctaatcatgg tataatatag ggtgatgaaa aattccaacg aggctgagat
    11281 gaaattactt tatactgata ttcgaacttc tttgacagaa attctaacaa gagaggcaga
    11341 agagctagtt gcagctggca agcgggtctt ctacattgcc cccaactctc tttcttttga
    11401 aaaggaacgc gccgtgctgg aatgcttgtc ccagcaggct tctttttcga ttaccgtcac
    11461 gcgctttgct caaatggctc gttatctggt cttgaatgat ttaccagtta aaactactct
    11521 tgatgatatc ggtcttgggt tggcctttta caaatgcctt gccgaactcg atcccaagga
    11581 cttgcgtgtt tatggcgcta ttaagcagga tcctcaattg atccagcagt taattgagct
    11641 ttaccatgag atgaccaaat ctcagatgag ttttttggac ttggagaatt taacagatga
    11701 ggataagagg acggatttac tcttgatttt tgagaaagta acagcctatc ttaatcaagg
    11761 tcagttagcc cagggaagtc agttgtccca tttgattgag gctattgaga atgacaaggt
    11821 aagtagtgat tttaatcaaa tcaccttggt cattgacggc tttactcgtt tttctgctga
    11881 ggaagagcgg gttgtggact tacttcacgg caaaggtgtt gagattgtta tcggggctta
    11941 tgctagtaag aaagcctata ccagtccttt tagcgagggc aatctctacc aagccagcgt
    12001 aaaatttctc catcatctgg cttctaaata ccaaacgcct gctcaggact gttctcaaac
    12061 tcatgagaag atggatagtt ttgacaaggc ctctcgtttg ttggagtctt cttatgactt
    12121 ttcagaactc gctttggatg tcgatgagaa agaccgtgaa aatttacaaa tctggtcttg
    12181 tttgacgcaa aaggaggagt tggagctagt agcccgtagc attcgtcaga aattacatga
    12241 gaactcagac ctgagctaca agcattttcg tattctcttg ggggatgtag cttcttacca
    12301 gttatctctc aaaaccattt ttgaccagta tcagattcct ttttatcttg gtagaagcga
    12361 agccatggct catcatccct tgactcagtt tgtcgagtct attttagctt taaaacgtta
    12421 ccgttttcgt caggaggatt tgattaatct tcttagaact gatttgtata ctgacctcag
    12481 tcagtctgat attgatgctt ttgagcaata tatccgctat cttggtatca atggcttgcc
    12541 agcctttcag caaaccttca ccaaatccca ccatggaaaa tttaatcttg agcgtttgaa
    12601 tgtcctccgc ctgagaattt tagcacctct tgaaaccctc tttgccagcc gaaaacaaaa
    12661 ggctgaaaaa ctcctacaaa aatggagtgt ctttctaaaa gaaggagctg tgaccaagca
    12721 gttacaagat ttgacaacca ctttggaagc tgtagaacag gaaagacaag ccgaagtttg
    12781 gaaggctttc tgccatgttt tagaacaatt tgcgactgtt tttgctggtt cacaggttag
    12841 tctggaagac ttcctagcct tgctccattc tggaatgagt ttgtcccaat accgtaccat
    12901 tccagcaaca gtggacactg ttctggtgca gagttacgat ttgattgcac cattgactgc
    12961 tgactttgtc tatgctattg gactaactca ggacaattta ccaaaaattt ctcaaaacac
    13021 cagtcttctg acagatgaag aaaggcaaaa cctaaaccaa gcgaccgaag aaggcgttca
    13081 attactgatt gccagcagtg aaaatctcaa gaaaaatcgc tacactatgc tttccttggt
    13141 caattctgct cgtaagcagt tgttcttgtc ggctccaagc ctttttaacg aaagtgaaag
    13201 taaggaatct gcctatcttc aagagttgat ccattttgga tttaggcgga gagagaagag
    13261 gatgaatcac aaaggactgt ctaaggagga tatggggtcc tatcacagtc ttttgtctag
    13321 tctggttgcc tatcaccagc agggtgagat gagcgatact gagcaagatt tgacttttgt
    13381 caaggttctg tcgcgtgtca taggtaaaaa actagatcag caaggtctgg aaaatccagc
    13441 catcccaatc agtccaagca gcaagacctt agccaaggac accttgcaag ctctctatcc
    13501 tgccaaacag gagttttacc tgtctacgtc gggtttgaca gagttttatc gcaatgaata
    13561 cagttatttc ctacgctacg ttttaggctt gcaggaggaa ttacgtttgc atcctgatgc
    13621 ccgtagtcac gggaatttct tgcatcgtat ctttgaacgc gccttacagt tgcctaatga
    13681 agattccttt gaccaacgtc tagaacaagc tattcaagaa accagtcaag aacgcgaatt
    13741 tgaagctatt tatcaagaaa gtttggaagc ccagtttacc aaggaagttt tgcttgatgt
    13801 tgcacggacg actggacata ttctccgaca caatccagcc atcgaaacca tcaaagaaga
    13861 agcaaatttt ggtggaaaag accaagcctt tattcaatta gacaatggac gcagtgtctt
    13921 tgtacgaggc aaggtggacc ggattgaccg tttgaaagct aatggagcga taggagtagt
    13981 agactacaaa tccagtctga ctcagttcca gtttcctcat ttctttaatg ggctcaattc
    14041 tcagttacca acctatcttg ctgccctaaa aagagaaggg gagcagaact ttttcggcgc
    14101 catgtacttg gaaatggctg aacctgtcca atctctgatg gcggtaaaaa gtcttgcagg
    14161 agcagtggta gaagccagca aatctatgaa ataccaaggg ctcttcttgg aaaaagaaag
    14221 cagttattta ggcgaatttt ataacaaaaa caaggctaat caactgacag atgaggaatt
    14281 tcagctccta ctggactaca atgcctatct ttacaagaaa gctgctgaga agattttagc
    14341 aggccggttc gccatcaatc cttatactga aaatggcaga agcattgccc catacgtcca
    14401 gcaacatcag gctattacag gctttgaagc caattaccat ctgggccaag cccgtttcct
    14461 aaaaaagttg gacctagctg atagcaagcg tctggtcgga gaaaaactca agcaagcttg
    14521 gcttgaaaaa ataagagagg agttgaatcg atgaagctta ttcccttttt aagtgaggag
    14581 gagattcaaa aactgcaaga agcagaagca aattcgagca aggaacagaa gaaaactgcc
    14641 gagcaaatcg aagctatcta cacttctggc cagaatatcc tggtctcagc atcggctggt
    14701 tctggaaaga cctttgtcat ggcagagcgc attctggacc aattggcgcg tggtgtcgaa
    14761 atttctcaac tctttatctc aacctttacc gtcaaggctg caactgaact taaagaacgt
    14821 ttagagaaaa aaatcagcaa gaaaatccaa gaaacagatg atgtcgagct caaacaacac
    14881 ttgggtcgcc agttggcaga cctacccaac gctgccatcg gaaccatgga ctctttcaca
    14941 caaaaattcc ttggcaaaca tggttatctg cttgatattg cacctaattt ccgtatttta
    15001 caaaaccaaa gcgagcaact tcttctcgaa aacgaagtct ttcatgaggt ctttgaagcg
    15061 cattaccaag gtaaacagaa agagaccttt agtcatttgc tgaaaaactt tgctgggcgt
    15121 ggcaaggacg aacggggtct gcgccagcag gtctataaaa tctatgactt cctccaatcc
    15181 accagcaatt ctcaaaagtg gctgagtgac tctttcctca aaggctttga gaaagctgat
    15241 tttaccagtg aaaaagaaaa actgactgag caaatcaaac aagccctttg ggatttggaa
    15301 agctttttcc gttaccatct ggataacgat gccaaggagt ttgcaaaggc tgcctattta
    15361 gaaaatgttc agttaattct ggatgaaatt tgctccctaa atcaggagtc cgatagtcag
    15421 gcttatcagt cagtgcttgc gcgtgttgtc gccatctcta aggagaaaaa cggtcgagct
    15481 ctgactaatg ccagccgtaa ggctgatttg aagcccctgg ctgatgccta caacgaagag
    15541 agaaagaccc agtttactaa actaggacaa ttatcagacc agatagcgat tctcgactat
    15601 caagaacgtt atcatggaga cacttggaaa ctagctaaaa ccttccaatc tttcatgagc
    15661 gattttgtag aggcttatcg tcagagaaaa cgacaggaaa atgcctttga attcgctgat
    15721 atcagccatt acaccattga gattttagaa aatttcccac aagttcgtga gtcttatcag
    15781 gagcgcttcc atgaagtcat ggtcgatgag tatcaggata ccaaccatat tcaagaacgg
    15841 atgctggaat tgttgtctaa tggccacaat cgctttatgg tgggagatat caagcaatcc
    15901 atctatcgtt tccgtcaggc agacccgcag attttcaatg agaaattcca acgctatgcg
    15961 caaaatcctc aagaaggcag gctcattctc ctcaaggaaa atttccgtag tagttcagaa
    16021 gtgctgtcaa caaccaatga tgtctttgaa cgtctcatgg accaagaggt cggcgaaatc
    16081 aactatgata acatgcacca gcttgttttt gccaatacca aactgactcc caatccagac
    16141 aacaaggcag aatttctcct ctacgacaag gacgatacag gtgaggaaga agagagtcaa
    16201 acagaaacga aactaacagg cgaaatgcgc ttagttatca aggagattct gaaacttcat
    16261 caagaaaaag gtgttgcctt taaggaaatt gcccttctga cctccagccg cagtcgtaat
    16321 gaccagattc tcctcgccct gtctgagtac ggaattcctg tcaaaactga cggagagcaa
    16381 aacaattatc tccaatccct agaagtgcaa gtcatgctag acactcttcg tgtcattcac
    16441 aatcccctgc aagactacgc cttggttgcc cttatgaagt ctccaatgtt tggttttgat
    16501 gaggatgagc tagcacgttt gtcccttcag aaagcagagg ataaagtcca cgaaaatctc
    16561 tatgagaaac tggtcaatgc acaaaaaatg gcaagtagtc aaaaaggttt gattcacaca
    16621 gctctagctg aaaaactaaa gcaattcatg gatatcctag cttcttggcg cttgtatgcc
    16681 aaaacccact ctctctatga cttgatttgg aagatttaca acgaccgttt ttattatgac
    16741 tatgttgggg ctttgccgaa tggtcctgct aggcaggcca atctctatgc cctagcactg
    16801 cgtgctgatc aatttgaaaa gagcaatttc aaaggtttgt cgcgttttat tcgtatgatt
    16861 gaccaagtct tagaagccca gcacgatttg gcaagcgtgg ccgtcgcacc gccaaaagat
    16921 gcagtagagc tcatgaccat ccacaagagt aaggggctgg agtttcctta cgtctttatc
    16981 ctcaatatgg atcaagattt caacaagcaa gactctatgt cagaagtcat tctcagtcgt
    17041 cagaatggtc ttggtgtcaa atatattgcc aagatggaga caggggcagt agaagaccac
    17101 tatcctaaaa ccatcaaact ctccattcct agcctgacct ataggcagaa tgaagaggaa
    17161 ttacagctag caagctattc tgagcagatg cgtttgctgt atgttgctat gacgcgggct
    17221 gagaaaaagc tctatcttgt cggcaagggt tctcgtgaaa agctggaagc caagcaatac
    17281 ccagcagcca aaaatgggaa actaaatagc aatactagac tgcaagcacg gaatttccaa
    17341 gattggcttt gggctatcag taaagtgttt actaaggaca agctcaactt tagttatcgt
    17401 tttattggcg aagatcagtt gaccagagaa gctatcggag agttggaaac caagagtcct
    17461 ctccaagata gctcccaagc agacaatcgt cagtcagata ccatcaaaga agctctgaaa
    17521 atgctgaagg aggtggaagt ttataatact cttcaccgcg cagctattga acttcctagt
    17581 gttcaaaccc caagtcaaat caagaaattc tacgaaccag ttatggatat ggaaggtgtc
    17641 gagattgctg gtcaaggtca gtcagtaggc aagaaaatca gcttcgattt gccagatttt
    17701 tcaacaaaag aaaaggtaac tggagctgag attggtagtg ctactcacga actcatgcag
    17761 agaattgacc tcagccagca actaaccctt gctagcctaa cagaaacact caaacaagtt
    17821 caaactagcc aagctgtcag agacaagatc aatcttgata aaattcttgc tttctttgac
    17881 acagtactcg gtcaggaaat tcttgctaat accgaccatc tctatcgcga gcaacctttc
    17941 tccatgctca aacgagacca aaagagtcag gaagactttg ttgtccgtgg tatccttgat
    18001 ggctatctgc tttacgaaaa caaaattgtt ctgttcgact acaagacaga ccgctatgat
    18061 gaaccaagtc aactcgtaga ccgctatcgt ggtcagttag ctctatacga agaggcttta
    18121 tcacgagcct attcgattga aaatattgaa aaatacttga ttttactcgg taaagacgag
    18181 gctcaagttg taaaagtata acttatactc tttgaaaatc tcttcaaacc acgtcagctt
    18241 cgccttgctg tatatatggt tactgacttc gtcagttcta tccacaacct caaaacagtg
    18301 ttttgagctg acttcgtcag ttctatccac aacctcaaaa cagtgttttg agctgactgc
    18361 ggctagcttt ctagtttgct ctttgatttt tattgagtat tagaaaggag acctcatgac
    18421 acttccagtt agaaaatccc tgcacgatgc agttttacag gcttcgaaag cggatacttg
    18481 ggaacaagct accaaggaat ggaatgaagt ttccttgatt tttaacggta tcggccgtag
    18541 caattgtgtc tgtggaaatg ccatcaaata cgcttatgaa ctctttaacg gtgtcacagg
    18601 ccaacgcctc tttccaattg gtagcgactg tgttcgtcat tttcatcgat tgtcccttga
    18661 ccagcaattg gaagaggaag aaaaactgct cagaaaggtt gaaaatctaa ccagaaaagc
    18721 tcagaaaaag gaaaaaatca aggtcaataa aagtgacttt gacgagcgac ttctaaaatg
    18781 gctctgggaa aaaggtgttt tcaaacccaa tcgtggcaat caatttgcgc ctgagagaga
    18841 ctaccagctt ttcctagaag tctttcaggg aggaagttgg accaaggcgg aaccaaagaa
    18901 aaaggctcgg atggaagaag tccttgaaaa gtgtatcaaa ccctttttac ttgggaaatc
    18961 ggatgaccaa ctctaccttg tcaagctagg caaggagaaa attgactacg aacaagaact
    19021 ccgtatccag gcagagaaag aacgcaagaa gagggataaa atcgccaagc aatatgcaga
    19081 caatctggtt ctagccatgg gacccgcaga gcgtgcttat caagattact ttggctttac
    19141 agagaccctg actcaagaag aacgcaagtg ggaaaaaatt ctttttggta aaaatagagc
    19201 agaacgggct atcaaggcca aacaatacca aaaagagctg gaaaaagacc aacgaattgc
    19261 cagtcaggat ccaattgaaa gaaaacagaa gcagacttgg ctcctcaatt cctattttcg
    19321 tgagcttcct gaagaaaaag ctcgattttc taggctctta ttagaatatc gaaaaagtgg
    19381 tgaagtaccc ttttcaactg aatacctgtc agatcatctc atcgactttt tctataaaat
    19441 gaaagccttt gaatttgaaa tcgcaccaga acaagtccga gattttctaa aaaaaagcct
    19501 gcaggaagac catcgctcat cagcacaagg aagctggata gaaggaattc tcctcaactg
    19561 cctcaaacca tttttagaac gattagtgat atgagtaaca cctaccgtgt aaatttcatg
    19621 gtaggtgtta ttgtacccca aaataatata aaacaaagta tgaaagcgca tctcaatttt
    19681 aagacttttt tgtaaattaa gagtataatt aaggtatact gcct
//
LOCUS       DAVKAU010000034        19398 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVKAU010000034 DAVKAU010000000
VERSION     DAVKAU010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.034"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            96..5399
                     /locus_tag="VWX48_001401"
     CDS             96..5399
                     /locus_tag="VWX48_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9172012.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQERVKTEDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HYPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EVGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTSLVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTTTDWPDNNKSKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(5565..7724)
                     /locus_tag="VWX48_001402"
     CDS             complement(5565..7724)
                     /locus_tag="VWX48_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU9172013.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(7721..8317)
                     /gene="recU"
                     /locus_tag="VWX48_001403"
     CDS             complement(7721..8317)
                     /gene="recU"
                     /locus_tag="VWX48_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU9172014.1"
                     /translation="MVNYPHKVSPQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLLAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            8383..8910
                     /locus_tag="VWX48_001404"
     CDS             8383..8910
                     /locus_tag="VWX48_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU9172015.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            8980..9309
                     /gene="gpsB"
                     /locus_tag="VWX48_001405"
     CDS             8980..9309
                     /gene="gpsB"
                     /locus_tag="VWX48_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU9172016.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            9330..9710
                     /gene="rnpB"
                     /locus_tag="VWX48_001406"
     ncRNA           9330..9710
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VWX48_001406"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9795..10952
                     /locus_tag="VWX48_001407"
     CDS             9795..10952
                     /locus_tag="VWX48_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU9172017.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            10965..12359
                     /gene="mapZ"
                     /locus_tag="VWX48_001408"
     CDS             10965..12359
                     /gene="mapZ"
                     /locus_tag="VWX48_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU9172018.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            12435..13859
                     /gene="gndA"
                     /locus_tag="VWX48_001409"
     CDS             12435..13859
                     /gene="gndA"
                     /locus_tag="VWX48_001409"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU9172019.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            13871..14560
                     /locus_tag="VWX48_001410"
     CDS             13871..14560
                     /locus_tag="VWX48_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9172020.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            14659..15681
                     /gene="cbpC"
                     /locus_tag="VWX48_001411"
     CDS             14659..15681
                     /gene="cbpC"
                     /locus_tag="VWX48_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU9172021.1"
                     /translation="MKLLKKMMQVALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYSLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDAENGDMKIGWTKVNGKWYYLNSSGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            15700..16821
                     /locus_tag="VWX48_001412"
     CDS             15700..16821
                     /locus_tag="VWX48_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9172022.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGMRLEGFPNS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDLTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGNGDM
                     KTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(16939..18171)
                     /locus_tag="VWX48_001413"
     CDS             complement(16939..18171)
                     /locus_tag="VWX48_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9172023.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(18214..19176)
                     /locus_tag="VWX48_001414"
     CDS             complement(18214..19176)
                     /locus_tag="VWX48_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU9172024.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKG
                     ISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLM
                     KKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
BASE COUNT         6004 a         3471 c         4408 g         5515 t
ORIGIN      
        1 tttatcaggg ttaagcattg cactttcaga ggaaggagta ttttttaaaa agaaaatgta
       61 aacgcttgct caaaaatgaa aggatttaga agtttatgaa taaaggatta tttgaaaaac
      121 gttgtaaata tagtattcgg aaattttcat taggtgttgc ttctgttatg attggagctg
      181 cattctttgg gacaagtccg gttcttgcag atagcgtgca gtctggttcc acggcgaact
      241 taccagctga tttagctact gctcttgcaa cagcaaaaga gaatgatggg cgtgattttg
      301 aagcgcctaa ggtgggagaa gaccaaggtt ctccagaagt tacagatgga cctaagacag
      361 aagaagaact attagcactt gaaaaagaaa aaccggctga agaaaaacca aaagaggata
      421 aacctgcagc tgctaaacct gaaacgccta agacggtaac ccctgaatgg caaacggtag
      481 agaaaaaaga acaacaggga acagtcacta tccgagaaga aaaaggtgtc cgctacaacc
      541 aactatcctc aactgctcaa aatgataacg caggtaaacc agctctgttt gaaaagaagg
      601 gcttgaccgt tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa gaagattctg
      661 aaaagggcaa atcacgcttt ggtgtcttct tgaaatttaa agataccaat aataatgttt
      721 ttgtcggtta tgacaaggat ggctggttct gggagtataa atctccaaca actagcactt
      781 ggtatagagg tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt ctctctatca
      841 ctctcaagtc agacggtcag ctaaatgcca gcaataacga tgtcaatctc tttgacacag
      901 tgactctacc agctgcggtc aatgaccatc ttaaaaatga gaagaagatt cttctcaagg
      961 cgggctctta tgacgatgag cgaacagttg ttagcgttaa aacggataac caagagaggg
     1021 taaaaacaga ggatacccct gcccagaaag aaacaggtcc ggttgttgac gatagcaagg
     1081 tgacttatga tacgatccag tctaaggtac ttaaggcagt aattgaccaa gccttccctc
     1141 gtgtcaagga atacaccttg aatggacata ctttgccagg acaggtgcaa caattcaacc
     1201 aagtctttat caataaccac cgaatcaccc ctgaagtcac ttataaaaaa atcaatgaga
     1261 caacagcaga gtacttgatg aagcttcgcg atgatgctca cttaatcaat gcggaaatga
     1321 cagtacgctt gcaagttgtg gacaatcaat tgcactttga tgtgaccaag attgtcaacc
     1381 acaatcaagt cactccaggt caaaagattg atgacgaaag aaaactactt tcttctatta
     1441 gtttcctcgg caatgcttta gtctctgttt ctagtgatca aactggtgct aagtttgatg
     1501 gggcaaccat gtcaaacaat acgcatgtca gcggagatga tcatatcgat gtaaccaatc
     1561 caatgaagga tttggctaag ggttacatgt atggatttgt ttctacagat aagcttgctg
     1621 ctggtgtttg gagtaactct caaaatagct atggtggtgg ttcgaatgac tggactcgtt
     1681 tgacagctta taaagaaaca gtcggaaatg ccaactatgt aggaatccac agctctgaat
     1741 ggcaatggga aaaagcttat aagggcattg ttttcccaga atacacgaag gaacttccaa
     1801 gtgctaaggt tgttatcact gaagatgcca atgcagacaa gaaagttgat tggcaagatg
     1861 gtgccattgc ttatcgtagc attatgaaca accctcaagg ttgggaaaaa gttaaggata
     1921 tcacagctta ccgtatcgcg atgaactttg gttctcaagc acaaaaccca ttccttatga
     1981 ccttggatgg tatcaagaaa atcaatctcc acacagatgg tcttgggcaa ggtgttctcc
     2041 ttaaaggata tggtagcgaa ggccatgact ctggtcactt gaactatgct gatattggta
     2101 agcgtatcgg tggtgtcgaa gacttcaaga ccctaattga gaaggctaag aaatatggag
     2161 ctcatctagg tatccacgtt aacgcttcag aaacttatcc tgagtctaaa tacttcaatg
     2221 aaaaaattct ccgtaagaat ccagatggaa gctatagcta tggttggaac tggctagatc
     2281 aaggtatcaa cattgatgct gcctatgacc tagctcatgg tcgtttggca cgttgggaag
     2341 atttgaagaa aaaacttggt gacggtctcg actttatcta tgtggacgtt tggggtaatg
     2401 gtcaatcagg tgataacggt gcctgggcta cccacgttct tgccaaagaa attaacaaac
     2461 aaggctggcg ctttgcgatc gagtggggcc atggtggtga gtacgactct accttccatc
     2521 actgggcagc tgacttgacc tacggtggct acaccaataa aggtatcaac agtgccatca
     2581 cccgctttat ccgtaaccac caaaaagatg cttgggttgg ggactacaga agttatggtg
     2641 gtgcagccaa ctatccactg ctaggtggct acagcatgaa agactttgaa ggctggcaag
     2701 gacggagcga ctacaatggc tacgtgacta acctctttgc ccatgatgtc atgaccaagt
     2761 atttccaaca cttcactgta agtaaatggg aaaatggtac accggtgact atgaccgata
     2821 acggtagcac ctataaatgg actccagaaa tgcgagtgga attggtagat gctgacaata
     2881 ataaagtagt tgtaactcgt aagtcaaatg atgtcaatag cccacaatat cgcgaacgta
     2941 cagtaactct caacggacgt gtcatccaag atggttcagc ttacttgact ccttggaact
     3001 gggatgcaaa tggtaagaaa ctttctactg agaaggaaaa gatgtactac ttcaatacgc
     3061 aggccggtgc aacaacttgg acccttccaa gcgattgggc aaagagcaag gtttaccttt
     3121 acaagctaac tgaccaaggt aagacagaag agcaagaact aactgtaaaa gatggtaaaa
     3181 ttaccctaga tcttctagca aatcaaccat acgttctcta tcgttcaaaa caaaccaatc
     3241 ctgaaatgtc atggagtgaa ggcatgcaca tctatgacca aggatttaac agtggtacct
     3301 tgaaacattg gaccatttca ggcgatgctt ctaaggcaga aattgtcaag tctcaagggg
     3361 caaacgatat gcttcgtatt caaggaaaca aagaaaaagt tagtctcact cagaaattaa
     3421 ctggcttgaa accaaatacc aagtatgccg tttatgtcgg tgtcgataac cgtagtaatg
     3481 ccaaggcgag catcactgta aatactggtg aaaaagaagt gactacttat accaataagt
     3541 ctctcgcgct caactatgtt aaggcttacg cccacaatac acgtcgtgac aatgctacag
     3601 ttaacgatac aagttacttc caaaacatgt acgccttctt tacaacagga tcggacgtct
     3661 caaatgttac tctgacattg agtcgtgaag ctggtgatca agcaacttac tttgatgaaa
     3721 ttcgtacctt tgaaaacaat tcaagcatgt atggagacaa gcatgataca ggtaaaggca
     3781 ccttcaagca agactttgaa aatgttgctc agggtatctt cccatttgta gtgggtggtg
     3841 ttgaaggtgt tgaagataac cgcactcact tgtctgaaaa acactatcca tatacacaac
     3901 gtggttggaa tggtaagaaa gtcgatgatg ttatcgaagg aaattggtca ctcaagacaa
     3961 atggactagt gagccgtcgt aacttggttt accaaactat tccgcaaaac ttccgttttg
     4021 aagcaggtaa gacctaccgt gtaacctttg aatacgaagt aggttcagac aatacatatg
     4081 cttttgtagt cggtaaggga gaattccagt caggtcgtcg tggcactcaa gcaagcaact
     4141 tggaaatgca tgaattgcca aatacttgga cagattctaa gaaagccaag aaggcaacct
     4201 tccttgtgac aggtgcagaa acaggggata cttgggtagg tatctactca actggcaatg
     4261 caagtaatac tcgtggtgat tctggtggaa atgccaactt ccgtggttat aacgacttca
     4321 tgatggataa tcttcaaatc gaagaaatta ccctaacagg taagatgttg acagaaaatg
     4381 ctctgaagaa ctacttgcca acggttgcca tgactaacta caccaaagag tctatggatg
     4441 ctttgaaaga ggcggtcttt aacctcagtc aggccgatga tgatatcagt gtggaagaag
     4501 cgcgtgcaga gattgccaag attgaagcct tgaagaatgc tttggttcag aagaaaacgt
     4561 ctttggtagc agatgacttt gcaagtctta cagctcctgc tcaggctcaa gaaggtcttg
     4621 caaatgcctt tgatggaaac ttatctagtt tatggcatac atcatggggc ggaggagatg
     4681 taggcaagcc tgcaaccatg gtcttgaaag aaccaactga aatcactgga cttcgttatg
     4741 ttccacgtgg atcaggttca aatggtaact tgcgtgatgt gaaacttgtt gtgacagatg
     4801 agtctggcaa ggagcatacc tttactacaa ctgattggcc agataacaat aagtcaaaag
     4861 atattgactt tggtaagaca atcaaggcta agaaaattgt ccttactggt accaagacat
     4921 acggagatgg tggagataaa taccaatctg cagcggaact tatctttact cgtccacagg
     4981 tagcagaaac acctcttgac ttgtcaggct atgaagcagc tttggctaag gctcagaaat
     5041 taacagacaa agacaatcaa gaggaagtag ctagcgttca ggcaagcatg aaatatgcga
     5101 cggataacca tctcttgacg gaaagaatgg tggaatactt tgcagattat ctcaaccaat
     5161 taaaagattc tgctacgaaa ccagatgctc caactgtaga gaaacctgag tttaaactta
     5221 gctctttagc ttccgatcaa ggtaagacgc cagattataa gcaagaaata gatagaccag
     5281 aaacacctga acaaatcttg ccagcaacag gtgagagtca atctgacaca gccctcttcc
     5341 tagcaggtgt tagcctagcc ctatctgctc tctttgtagt aaaaacgaag aaagactagt
     5401 atttagtaaa acctcttaac aagattacgg aagcagtctc tatcttttcc aatgaggttt
     5461 atagtacaga aaaagtctga gaagatgtct tctcagactt ttgttaagca cataaataca
     5521 atagtgctat gacaaaatca cccagaaaat ctgggtgata aatgttatgg ttgtgctggt
     5581 tgaggattct gattttgttg atcaggggtt gtatttgatt gttgcgtatt attgttagga
     5641 ttggtagtcg tactattatt tgtgcttgga gtggttgagc tagactgtga agttgaacta
     5701 tctgatgatg agcttgaact ttcagttgat gggggttgtt gtggagcagg tgagttccac
     5761 gtagaacgag caccattttt aaatacgaat tctccatttc tgtagagccc ctctggtata
     5821 ttccaatcct ctggattgct tccttcagac aggtaggtca tcatagagcg gtaaactttg
     5881 gcagcgaccg taaggccatt gcctacaagt ggtgtcagac ggttagaata gcctgtccat
     5941 acagccattg aatatttacg cgtatagcca gcaaatagtt cgtcaggtgc tacaaattga
     6001 gaggtcttga tgtggttttc aatttcctcg tctgtatagt tagaggttcc tgttttacca
     6061 gcctgaggga gccaagcaag ataggcattt cgtccagttc cataactcaa gactgttttc
     6121 atcatgtcgg tcatcatata ggctgtcgtt tccttcatgg cacgagttcc gacattagag
     6181 aactcttttt cactcccatc actaaagacg actttatgga tatacattgg tttatagtaa
     6241 gttccaccat ttgcaaaggc agcgtaagca gcagccatct tttcactact tgctccatat
     6301 tttttgtctg attcggttgt gttacttgaa atggcatttg agtagtgaat acttgggtag
     6361 tcgattccta gaccatttag gaaagtcttg gcgcggttga gtccgacctt gtttagagtt
     6421 tccacggctg ggacgtttcg cgattgttgc agggcgtatt gcaaggtgat gttgccaaag
     6481 tagcccctat cccagttata aacaggagta tttgtcccag ggtagttata gggctcatcg
     6541 tgaacgatag tagcagttga atcgtagaca ccgtactcca aggcaggagc atagtctgtg
     6601 atcggtttca tagttgatcc ccagtcgcgg tttgtttcta ctgcttggtt aattccgaag
     6661 gaaacattac ttgactgatg gcgtgctcct agctgggcaa tgactttacc gttagaaaca
     6721 tcaacaatgg tagaagcgac ttgcaattca tcgtctggat aggcaacgta ttcgtctgta
     6781 ttgtaaatat cccacagatg tttttgagct tcttggtcta catttgtgta gacatccatc
     6841 ccagttgtga gcaggttata gcctgtttct tcttcaactt gattgatgac ttccttgagg
     6901 taattatcca tgtaagcagg gtaattactt gctgatttga gactttgtag tccatcagta
     6961 attggtgtat tgactgcttt ctcatactgt tcagcagaga tgtagccttg atttttcatt
     7021 tcagataaga ccaagtttcg gcggtcttgg gctgcttctg gatgtgaata ggggtcatat
     7081 tggtttggtg cctgaggcat tccagccagc aaggctaact gaggtaaact taaattattg
     7141 aggtctttac catagtagtt ttgagctgct gtctgcattc catagttccc attagacatg
     7201 tagaccttat ttatatagta ggtcaagatt tcttgcttgg ttgctttttg ttctaactga
     7261 atcgctaacc aagcttcctg agccttacga gaaatagtct ggtcggaagt cgaagttgaa
     7321 aagtaagtca acttaatcaa ctgttgagtg agagttgatc caccttggag ggaattgctt
     7381 tgcagattgc gcaagaaagc tcccaggata cggatggtat caatccccct gtggtcgaag
     7441 aagcgatggt cttcgataga aacgattgcc ttaaccaaat ctgtgggaat atcattagct
     7501 tgggcattga cgcggcgttc agaacccaag tcagcaatga gttgattttt attgtcgtag
     7561 attttactag aagttgttgc aactagttta ctctcggata ggctaggagc cttgctaacg
     7621 tagtagaaaa aaactcctcc gcctaagaca atggctgcga taaccaagct taagaagcta
     7681 atgctcagat acttgattag gcgcagaatc gttggtttgt tcatcttgtt ttaccaccta
     7741 ataaatgttc tttgataaca ttgagataag gaatttgagg gaaggcacca gccttgattt
     7801 catatccata ttctcgaata tattcaagtg gcattgattt ttgtccctta tcttgatgat
     7861 agaagcgaat caaatcgaat gccagcaata agtaggtttc ttgctgagaa gaaaagtgaa
     7921 gaaggacaaa gcagattcct tgttgggcaa ggacttgttc catatgctga atctgatgtg
     7981 gatgaaaatt tttcatcgga atcgcacgtt tttgttttgt ttccttgact tcaaagtcga
     8041 tgtaatatcc attataaacg ccagaatagt ccgtcgttga agcttgtcga aaataggctt
     8101 caacaatctt ggcacgactt cgttgtggat agtccacttg tacgatttga ataggagttg
     8161 gtttcttatg tataacagcc aagccctgag acaaatagta gtcgttggta gcattgatca
     8221 tcttttcaaa agacattcct cgatttgcga aatttttggg ttgagaaaga gatgtttgtc
     8281 ttttttgtgg tgaaacttta tgtggatagt tgaccataat tctccttatt ggtacaataa
     8341 catcacttta ttataccata atttgcacag aaagggttaa aaatggctac agctttggtt
     8401 ttaggctatt ctgcttttga tttgggttta ttttctgata aggatcctcg tcttaaattg
     8461 attaaaaaag cgatacgtaa agatttagag gctatggcag cagatggggt gtcttggctt
     8521 gtgtttacag ggagtttggg ttttgaatat tgggttttag aggttgctca ggagatgaaa
     8581 accgaatacg gtttccagtt ggccaccatt tttgcttttg aaacccatgg ggaaaattgg
     8641 aatgaaggca atcagatgaa actgagtcgc tttaagcagg tagactttgt caaatatgcc
     8701 tatcctcgct atgaacacaa ggggcagtta agagattacc agcagttttt gctggaaaac
     8761 acgactagtt cctatctttt ttatgatgaa gaaaatgaaa caaaactagc ttatttttac
     8821 caaaagatga aaaatcaaga ggactatttt ataaagagat taacatttga tcaattaaat
     8881 gaacttgctg aaaatttttc cgaaaattga agctttgacc ttgatttttg tttgcctttt
     8941 tttatataat aatactagca agcgagaatg gagagagaca tggcaagtat tattttttca
     9001 gcgaaagata tttttgaaca agagtttgga cgtgaagtcc gtggctataa taaagtagaa
     9061 gttgacgagt ttttagacga tgtcatcaag gactatgaaa cctatgctgc cttggtcaag
     9121 tcacttcgtc aggaaattgc ggatttgaag gaagaattaa ctcgtaaacc gaaaccttca
     9181 ccagttcaag cagaacccct tgaagcggca attacaagtt ctatgacgaa ttttgatatt
     9241 ttgaaacgcc tgaatagatt ggaaaaagaa gtttttggta aacaaatttt agataactca
     9301 gatttttaag tagttatttg agatgtgcaa tttttggata atcgcgtgag gagaattgct
     9361 tctcatgagg aaagtccatg ctagcacagg ctgtgatgcc tgtagtgttt gtgctaggcg
     9421 aaaccataag cctagggacg agaaatcgtt acggcagttg aaatggctaa gtccttggat
     9481 aagccagagt aggcttgaaa gtgccacagt gacggagtct ttctggaaac agagagagtg
     9541 gaacgcggta aacccctcaa gctagcaacc caaattttgg tcggggcatg gagtacgcgg
     9601 aaacgaacgt agtattctga ctgctatcag ctagagctgt tagtggtaga cagatgatta
     9661 tcgaaggaag tggtcctagt cacttctgga acaaaacatg gcttatagaa aattgcatat
     9721 aggttggggc tgagaaattt tctcaacctc attttttaaa gtggacatat agaaaggtct
     9781 tgcaagactg taacatgaaa aaagaattta atttaattgc aactgtggca gcagggcttg
     9841 aggctgtcgt tggtcgtgaa gtgcgagagt tgggctacga ttgtcaggtt gaaaatggac
     9901 gtgttcgttt tcaaggagac gtgagagcta ttatcgaaac caacctttgg cttcgggcag
     9961 cagatcgtat caaaattatc gtaggaacgt tcccagctaa gacttttgaa gagctatttc
    10021 agggagtttt cgctttagat tgggaaaatt atttaccact tggagctcgg ttcccgattt
    10081 caaaagctaa atgtgttaag tccaaacttc acaatgagcc cagtgttcag gctatttcta
    10141 agaaagctgt tgtcaagaaa ttgcagaaac actatgctcg cccagaaggg gttcctctga
    10201 tggagaatgg tccagagttt aagattgagg tctctattct caaagatgtg gcaactgtca
    10261 tgattgatac gaccgggtct agcctcttta aacgtggtta tcgtaccgaa aaaggtggcg
    10321 ctcctatcaa ggaaaatatg gcagcagcca ttttacaact ttctaactgg tatccagaca
    10381 agcctttgat tgatccgacc tgtggttcgg ggactttctg tattgaggca gttatgattg
    10441 ctagaaagat ggcgccaggt cttcgtcgct cttttgcatt tgaggaatgg aactggatca
    10501 gcgatcgctt gattcaagaa gtgcgcacag aagcggctaa aaaagtagaa cgtaagcttg
    10561 agttggatat catgggctgt gatattgatg ctcgcatggt ggaaattgct aaggccaatg
    10621 ctcaggcagc tggtgttgca ggagatatta cttttaagca gatgcgcgtg caggatttac
    10681 gttccgataa aatcaatgga gtaatcattt ccaatccgcc ttatggtgaa cgtttgtcag
    10741 atgatgcagg ggtgaccaag ctctatgctg agatggggca agtatttgca ccgctgaaaa
    10801 cttggagcaa atttatcctg actagtgatg aagcttttga aagcaagtat ggtagccaag
    10861 cagataagaa gcgtaagtta tacaacggaa ccttgaaagt ggatctatat caatattttg
    10921 gtcagcgtgt caaacggcaa gaggtaaaat agaaagggat actcatgagt aaaaaaagac
    10981 gaaatcgtca taaaaaagaa ggtcaagaac cgcaatttga ttttgatgaa gcaaaagagc
    11041 taacagttgg tcaagctatt cgtaaaaatg aagaagtgga agcaggagtc ttgcctgagg
    11101 attccatttt ggacaagtat gttaagcaac acagagatga aattgaggcg gataagtttg
    11161 cgactcgtca atacaaaaaa gaggagttcg ttgaaactca gagtctggat gatttaattc
    11221 aagagatgcg tgaggctgta gagaagtcag aagcttcttc ggaggaagtt ccatcttctg
    11281 aagacatctt actacccttg cctctggacg atgaggagca aggcttggat cctctattgc
    11341 tagatgatga aaatccaaca gaaatgactg aagaagtgga agaggagcaa aacctttctc
    11401 gtctggatca agaggactca gaaaagaaaa gtaaaaaagg ctttattttg accgttttgg
    11461 cgcttgtatc agtaattatt tgtgtcagtg cttattatgt ctaccgtcaa gtggctcgtt
    11521 cgaccaagga aattgaaact tctcaatcaa ctacagccaa tcaatcggat gtggatgatt
    11581 ttaatacact ttatgacgcc ttttacacag atagcaataa aacggctttg aaaaatagcc
    11641 agtttgataa actgagtcaa ctcaaaacct tgcttgataa actggaaggt agtcgtgaac
    11701 atacgcttgc caaatctaaa tatgatagtc tagcaacgca aatcaaggct attcaagatg
    11761 tcaatgcaca atttgaaaaa tcagctattg tggatggtgt gttggatacc aatgccaaag
    11821 ccaaatcgga tgctaaattt acagatatta aaactggaaa tacggagctt gataaagtgc
    11881 tagataaggc tatcagtctt ggtaagagcc agcaaacaag tacttctagc tcaagtttaa
    11941 gtcaaactag cagctcaagt tcaagtcaag caagttcaaa tacgactagt gagccaaaac
    12001 caagtagttc aaatgagact agaagtagtc gcagtgaagt caatatgggt ctctcgagtg
    12061 caggggttgc tgttcaaaga agtgccagtc gtgttgccta taatcagtct gctattgatg
    12121 atagtaataa ctctgcctgg gattttgcgg atggtgtctt ggaacaaatt ctagcgactt
    12181 cacgttcacg tggctatatc actggagacc aatatatcct tgaacgtgtc aatatcgtta
    12241 acggcaatgg ttattataac ctctataagc cagatggaac ctatctcttt acccttaact
    12301 gtaagacagg ctactttgtc ggaaatggcg ctggtcatgc ggatgacttg gactactaag
    12361 cagtcgttac aaaattcttt cttttcaaaa gtaaaaatga taaaataaaa caaatgaaac
    12421 aagaggagtg tcaaatgaca aaagctaact ttggtgtcgt aggtatggcc gtaatgggtc
    12481 gtaaccttgc ccttaatatt gaatcacgtg gttacacagt tgctatctac aaccgtagta
    12541 aagaaaaaac ggaagatgtg attgcttgcc atcctgaaaa gaactttgta ccaagctatg
    12601 acgttgaaag ttttgtaaac tcaatcgaaa aacctcgtcg tatcatgctg atggttcaag
    12661 ctggacctgg tacagatgct actatccaag cccttcttcc acaccttgac aagggtgata
    12721 tcttgattga cggtggaaat actttctaca aagataccat ccgtcgtaat gaagaattgg
    12781 caaactcagg tatcaacttt atcggtactg gagtttctgg tggtgaaaaa ggtgcccttg
    12841 aaggtccttc tatcatgcct ggtggacaaa aagaggccta cgaattggtt gcggatgttc
    12901 ttgaagaaat ctcagctaaa gcaccagaag atggcaagcc atgtgtgact tacatcggtc
    12961 ctgatggagc tggtcactat gtgaaaatgg ttcacaatgg tattgagtac ggtgatatgc
    13021 aattgatcgc agaaagctat gacttgatgc aacacttgct aggcctttct gcagaggata
    13081 tggctgaaat ctttactgag tggaacaagg gtgaattaga cagctacttg atcgaaatca
    13141 cagctgatat cttgagccgt aaagacgatg aaggccaaga tggaccaatc gtagactaca
    13201 tccttgatgc tgcaggtaac aagggaactg gtaaatggac gagccaatca tctcttgacc
    13261 ttggtgtacc attgtcactg attactgagt cagtgtttgc acgctacatt tcaacttaca
    13321 aagaagaacg tgtacatgct agcaaggtgc ttccaaaacc agctgccttc aactttgaag
    13381 gagacaaggc tgaattgatt gaaaaaatcc gtcaagccct ttacttctca aaaatcattt
    13441 catacgcaca aggatttgct caattgcgtg tagcctctaa agaaaacaac tggaacttgc
    13501 catttgcaga tatcgcatct atctggcgtg atggctgtat catccgttct cgtttcttgc
    13561 aaaagattac agatgcttac aaccgcgatg cagatcttgc caaccttctt ttggacgagt
    13621 acttcttgga tgttactgct aagtaccaac aagcagtacg tgatatcgta gctcttgcgg
    13681 ttcaagcagg tgtgccagtg ccaactttct cagcagctat tacttacttt gatagctacc
    13741 gttcagctga ccttccagct aacttgatcc aagcacaacg tgactacttt ggtgctcaca
    13801 cttaccaacg taaagacaaa gaaggaacct tccactactc ttggtatgac gaaaaataag
    13861 taggtcagcc atggggaaac ggattttatt acttgagaaa gaacgaaatc tagctcattt
    13921 tttaagtttg gaactccaga aagagcagta tcgggttgat ctggtagagg aggggcaaaa
    13981 agccctctcc atggctcttc agacagacta tgatttgatt ttattgaatg ttaatctggg
    14041 agatatgatg gctcaggatt ttgcagaaaa attgagccga actaaacctg cctcagtcat
    14101 catgatttta gatcattggg aagacttgca agaagagctg gaagttgttc agcgttttgc
    14161 agtttcatac atctataagc cagtccttat cgaaaatctg gtagcgcgta tttcggcgat
    14221 cttccgaggt cgggacttca ttgatcaaca ctgcagtctg atgaaagttc caaggaccta
    14281 ccgcaatctt aggatagatg ttgaacatca cacggtttat cgtggtgaag agatgattgc
    14341 tctgacccgc cgtgagtatg accttttggc gacacttatg ggaagcaaga aagtattgac
    14401 tcgtgagcaa ttgttggaaa gtgtttggaa gtatgaaagt gcgaccgaga caaatatcgt
    14461 agatgtctat atccgctatc tacggagcaa gcttgatgtt aaaggccaaa aaagctacat
    14521 taaaactgtg cgtggtgttg gatataccat gcaagaatag aaaagcagtt gcagttgtgt
    14581 aactgctttt ttgaggagtt tttatatatt gacatacaat ctagttttta ctacaatcgt
    14641 tttaggagga tatataaaat gaagcttttg aaaaaaatga tgcaagtcgc attagcagtc
    14701 tttttctttg gtttgctagc tacaaatacg gtatttgcga ataccacagg tggccgattt
    14761 gttgataagg ataatagaaa atattatgta aaagatgatc ataaagcaat ctattggcat
    14821 aaaatagacg gtaaaactta ctattttggt gatattggag agatggttgt cggttggcaa
    14881 tacttagaaa ttcctggaac aggttatcgt gataatttat tcgataacca accagttaat
    14941 gaaattggcc ttcaggagaa gtggtactat tttggacaag atggtgcttt gctagaacaa
    15001 acagataaac aagtactaga ggcaaaaacg tctgaaaata caggaaaagt atacggtgaa
    15061 caatattctc tatctgctga aaagagaact tattattttg ataataatta tgctgtaaag
    15121 acaggctgga tttatgaaga gggtcattgg tattatttaa ataagctagg aaattttggc
    15181 gatgattctt acaatccact accaattggt gaagttgcta agggttggac tcaagatttt
    15241 catgttacta ttgacattga tagaagcaaa cctgctccat ggtactacct agatgcttca
    15301 ggtaagatgc ttacagattg gcaaaaagta aacggaaaat ggtattattt tggctcctct
    15361 ggttctatgg caacaggttg gaaatatgta cgaggcaaat ggtattactt agataataaa
    15421 aatggtgata tgaaaacagg atggcaatac cttggtaaca agtggtacta cctccgttca
    15481 tcaggagcta tggtaactgg ctggtatcaa gatggttcaa cttggtacta tttagatgct
    15541 gaaaatggtg atatgaaaat aggttggaca aaagtaaatg gaaaatggta ttatctcaat
    15601 tcctctggag caatggttac aggtagtcaa actatcgatg gtaaagttta taacttcgct
    15661 tcatctggtg agtggattta atgttggagg atatataaaa tgaagctttt gaaaaaaact
    15721 atgcaagctg gactaacagt aattttcttt ggtttgctag ctacgaatac agtatttgca
    15781 gataactctg aaggatggca gtttgtccaa gaaaacggta gaacctatta caaaaagggg
    15841 gacctcaaag aaacctactg gcgagtgatt gatggtaagt actattattt tgattctcta
    15901 tctggagaga tggttgtcgg ctggcaatat atcccgtttc catctaaagg tagtacaatt
    15961 ggtccttacc caaatggtat gagattagaa ggttttccaa attcagagtg gtactacttc
    16021 gataaaaatg gagtgctaca agagtttgtt ggttggaaaa cattagagat taaaactaaa
    16081 gacagtgttg gaagaaagta cggggaaaaa cgtgaagatt cagaagataa agaagagaaa
    16141 cgttattata cgaactatta ctttaatcaa aatcattctt tagagacagg ttggctttat
    16201 gatcagtcta actggtatta tctagctaag acggaaatta atggagaaaa ctaccttggt
    16261 ggtgaaagac gtgcggggtg gataaacgat gatttgactt ggtactattt agatccaaca
    16321 actggtatta tgcaaacagg ttggcaatat ctaggtaata agtggtacta cctccgttcc
    16381 tcaggagcaa tggccactgg ctggtatcag gaaggtacca cttggtatta tttagaccag
    16441 ccaaatggcg atatgaaaac aggttggcaa aaccttggga acaaatggta ctatctccgt
    16501 tcatcaggag caatggcaac tggttggtat caggaaggta ccacttggta ttatttagac
    16561 cagccaaatg gcgatatgaa aacaggttgg caaaaccttg ggaacaaatg gtactatctc
    16621 cgttcatcag gagcaatggc aactggttgg tatcaagatg gttcaacttg gtactaccta
    16681 aatgcaggta atggagatat gaagacaggt tggttccagg tcaatggcaa ctggtactat
    16741 gcttatagct caggtgcttt ggcagtgaat acgaccgtag atggctattc tgtcaactat
    16801 aatggcgaat gggttcggta atgacagggc gcttataatt atattagaac actcgcttaa
    16861 tcaaagaagt gactttgttg tacttgacct gacgattggg gagattaaaa gcatgtgaaa
    16921 tctacacatg ctttttcgtt agttatgagt gttgaacttg actaaccatt gacaaaagat
    16981 aagagcaatt aaaataagat acaaaaatat caatgctaac tgcaccgaaa cgcccgatgc
    17041 tatggatagg gctaataggg agagcaggga cggggcgaga atgtccactg tgctcagagc
    17101 agagcccacc gtccccatct tgtcactggg gatatgggca aagacagctg cttgtaggcg
    17161 agggctgaga atgccgataa tcgtagaact gatgaaactg gtcatgaaaa ttacgatata
    17221 ggcttgacaa aggatactag ttattagagt caatagggaa atctcacaga aaaccaagag
    17281 gtgcgtgaaa cggatatttt taaatagatt actgctggtc atattgccaa ggatagctcc
    17341 acaagacatg atgatggaga gcagggcgag gagttgccca atgctcagtt gtgctagtgt
    17401 ctgttggatg aagcggaggg caatcagccg aggggacaca tccaagatgg caatcatact
    17461 ggtcgtcaga aacagtagta tgacggtatc ttttaacctc aggagcacag ccagcgactg
    17521 tttaagatgt tgaaaatatt tcttaaaact cagtgctgta tgtgacattt caattctttt
    17581 ttcaacctca tacaaggtat gtcgaataac atacaggccc aaaaaggcaa tgacaaaagt
    17641 cagagtgttg ataagggaaa tagtttgaat acttataaca ttgataagga atgcgccagc
    17701 cagattggcg acaatacgga caaccctcat cagagactgc ctgaacccca tggcatcatg
    17761 caggtcgtcc ttaattacac tgatgtagag ggcgttcatc atgtaggcag acaggtagct
    17821 caaggtgtca gagatgaggt tgatgatgac aatcataatg actgaaacta atgaaaaggg
    17881 cgacaagacg agaaatactg tcaaaatagc gtagagcagg attttgattt tggcaatcca
    17941 gagtgcgtgt ttgactctat tttcttgaaa atctcctaga atcccgagaa agagttgcga
    18001 tagtagggga accatctctg aaatggaaat cagtaaaatc gctagcggag cgaaattgta
    18061 ctgagccaca taattgataa tggcgaggta gaaaatactg tcgccgaatg atgaaaaaca
    18121 gctgtttagc agcaactgtc tatatatgtt gtttgtccaa aataatttca tacttttctc
    18181 cttatgtctg cacatcgaat gggaatttat tatttaatag acaccaatat accccatgct
    18241 tcctattccg aagtcaaaca aatctgcttt accactatct ccttgaaaca tcagtaaacc
    18301 gtgatcatct cgttcagaac atgctaaaat tacctgttgg atttttttca tcagtaattt
    18361 gttttgattg tagacagtgg tttgtagtaa gctagttatt ccgtggcaat atcctgtcat
    18421 catttttaga tgatggttaa aaacaaattc ttgatattta ctaataatat ctttgtttcc
    18481 gtcacaatcg tacatacaaa gatataagat tattccggaa attcctttgc accaagaaag
    18541 ttgtaaattt cctaaatttt cagtattaga agtaactttt tctaataatt tttttaattc
    18601 agtatggaat gtatggagat cattatagaa catagaaggt tctaagactt tagaataggc
    18661 aaataaagca tatgcaattc cacaatatcc atgagcaaag ctatagtcta aaatgctttc
    18721 tttggctgta tctctttgta ggaaataatg ataaatttcc cctatactat tgtggatgaa
    18781 aattttaaga gtattgtcat tggtaaattg atagtatttt attaatgata ataggacacc
    18841 agattttccc aatgcaaagt ctatttcctc tagagtatca taattctcta ttaatttttt
    18901 agcggtgacg tttgctaatt gtagatagta ttgattttta ctgatagaaa ataaatgtag
    18961 gagtaaccat agatagcctg catcaccaaa tagcagtgag tattgatatt catatgtatg
    19021 tgtcgttcta attgtcactg ccttcttgat gatagagagt attttagaat ccagttctgg
    19081 ggggtacaat ttatttagag gaaacagtag tccagctatt ccgtgttgga atgataaatt
    19141 acttacgaaa tttccaaatt ctgttgaaga agtgatcctt ccttcagaat ttacagtttt
    19201 atctagtaaa aattgtagaa cactattaca ttctgttttg taatcatatt tatgttcctc
    19261 tattttttta attttgacta aattatttgt ttgacttaaa tttagtagac attgtaacca
    19321 aaatagttgc tcatctgtga gctgaccttg agtatgtgat agttctagta attgaatagg
    19381 atcctttagt tagattca
//
LOCUS       DAVKAU010000035        19162 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVKAU010000035 DAVKAU010000000
VERSION     DAVKAU010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.035"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(124..327)
                     /gene="blpN"
                     /locus_tag="VWX48_001415"
     CDS             complement(124..327)
                     /gene="blpN"
                     /locus_tag="VWX48_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU9172025.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(343..573)
                     /locus_tag="VWX48_001416"
     CDS             complement(343..573)
                     /locus_tag="VWX48_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU9172026.1"
                     /translation="MNTKMMSQFSVMDNEMLDRIEGGIFGVDDALFWAGLGTAICAAS
                     GVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            863..1450
                     /locus_tag="VWX48_001417"
     CDS             863..1450
                     /locus_tag="VWX48_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU9172027.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            1443..3020
                     /locus_tag="VWX48_001418"
                     /pseudo
     CDS             1443..3020
                     /locus_tag="VWX48_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            3031..4392
                     /locus_tag="VWX48_001419"
     CDS             3031..4392
                     /locus_tag="VWX48_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU9172028.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLETTTDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            4449..4604
                     /gene="blpC"
                     /locus_tag="VWX48_001420"
     CDS             4449..4604
                     /gene="blpC"
                     /locus_tag="VWX48_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU9172029.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(4649..5989)
                     /locus_tag="VWX48_001421"
     CDS             complement(4649..5989)
                     /locus_tag="VWX48_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9172030.1"
                     /translation="MYIFWIILYTLITNGLEIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMIGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(6002..6739)
                     /locus_tag="VWX48_001422"
     CDS             complement(6002..6739)
                     /locus_tag="VWX48_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9172031.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(6744..7082)
                     /locus_tag="VWX48_001423"
     CDS             complement(6744..7082)
                     /locus_tag="VWX48_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9172032.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVRYARRRYRE
                     IRQKWLKEGE"
     gene            7357..7686
                     /locus_tag="VWX48_001424"
     CDS             7357..7686
                     /locus_tag="VWX48_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9172033.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7854..8903)
                     /locus_tag="VWX48_001425"
     CDS             complement(7854..8903)
                     /locus_tag="VWX48_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9172034.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8900..9631)
                     /locus_tag="VWX48_001426"
     CDS             complement(8900..9631)
                     /locus_tag="VWX48_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172035.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9699..10109
                     /locus_tag="VWX48_001427"
     CDS             9699..10109
                     /locus_tag="VWX48_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU9172036.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10119..10406
                     /locus_tag="VWX48_001428"
     CDS             10119..10406
                     /locus_tag="VWX48_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172037.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10568..10852
                     /locus_tag="VWX48_001429"
     CDS             10568..10852
                     /locus_tag="VWX48_001429"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172038.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSSKHCFEVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(11174..12310)
                     /gene="dnaJ"
                     /locus_tag="VWX48_001430"
     CDS             complement(11174..12310)
                     /gene="dnaJ"
                     /locus_tag="VWX48_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU9172039.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVYGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12515..12769)
                     /locus_tag="VWX48_001431"
     CDS             complement(12515..12769)
                     /locus_tag="VWX48_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172040.1"
                     /translation="MLVTVERNGNVIYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHIC
                     QELHLYKTQDPHYNKFEFDLAKRSLKITTRDNTTIFISNE"
     gene            complement(12881..14704)
                     /gene="dnaK"
                     /locus_tag="VWX48_001432"
     CDS             complement(12881..14704)
                     /gene="dnaK"
                     /locus_tag="VWX48_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU9172041.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15134..15658)
                     /gene="grpE"
                     /locus_tag="VWX48_001433"
     CDS             complement(15134..15658)
                     /gene="grpE"
                     /locus_tag="VWX48_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU9172042.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSKLDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15685..16719)
                     /gene="hrcA"
                     /locus_tag="VWX48_001434"
     CDS             complement(15685..16719)
                     /gene="hrcA"
                     /locus_tag="VWX48_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU9172043.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16883..17392)
                     /locus_tag="VWX48_001435"
     CDS             complement(16883..17392)
                     /locus_tag="VWX48_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU9172044.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            18000..>19162
                     /locus_tag="VWX48_001436"
     CDS             18000..>19162
                     /locus_tag="VWX48_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9172045.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNG"
BASE COUNT         5984 a         4085 c         3463 g         5630 t
ORIGIN      
        1 tgatgttaat tcaatagtct tttgtttttt atcggagata cttatggata gataaataag
       61 ataggtttga aaagcgaaga gaataataaa gaatatagcc ttcataaaat ttagctttca
      121 tttttatgat gtagcggtat aggctaaata tccacaaacc actgctcctc caattcctcc
      181 tattgcagcg ccccatggtc ctagaagtct cccatatttc actccacccg ctgcacaacc
      241 taaagcagca actacagctg ctcctccgga attacctcca taaacctcac tcagcattgt
      301 ttcatttata ttacaataag tattcataca agtctccttt tgttaaaatc cacccgttgc
      361 ccctgttact cctgcccaaa gagccacacc aaatttagct cctatgtatc cacatgctcc
      421 cataaatggc gctccaacac cactcgcagc acaaatagct gtccctaacc ctgcccaaaa
      481 caaagcatcg tcaactccaa atattcctcc ctctatccta tcaagcattt cattatccat
      541 aacagaaaat tgtgacatca tttttgtatt catgacaaat actccttttt tatttttgtc
      601 ttgttgtaac tttgataagt ttagtatatc atcgtttttt aaaatttttc atccagatct
      661 tgaattgtca tcgaaacgtc ttgaattagc ttttttattt caagccacct ctatttcaag
      721 ccacctctaa atgtttaaaa aaaataattt ctaatcactt ttttaccatt caggaagttt
      781 taatgactat tcaagatttc ataaaatatg aacttagttt tatgacataa tagacctatc
      841 cactatatga aaggaattgc caatgacttc ttataaacgt acatttgttc ctcaaataga
      901 tgcgagagac tgtggtgtcg ctgccttagc ctcgattgct aaattctatg gttcagattt
      961 ttctctagct cacttgagag aacttgcaaa gaccaataaa gaagggacga ctgctcttgg
     1021 cattgtaaaa gccgctgatg aaatgggctt tgaaacaaga cctgttcaag cagataaaac
     1081 gctctttgac atgagtgatg tcccctatcc atttatcgtt cacgttaaca aagaaggaaa
     1141 actccaacat tactatgttg tctatcaaac aaagaaagac tatctgatta ttggtgatcc
     1201 tgacccttct gtaaaaatca ctaaaatgtc aaaagaacgc tttttctatg aatggactgg
     1261 agtagctatt tttctagcta ccaaacccag ctatcaaccc cataaagata aaaagaatgg
     1321 tctactaagc aagcttcctt cctctgattt tcaaacaaaa atctctcatt gcttacattg
     1381 ttctctcaag cttattggtc actattatca atataggtgg ttcttactat ctccaaggaa
     1441 tcttggatga atacattcca aatcagatga aatcaacttt aggaatcatc tcagttggtc
     1501 tggttatcac ctatatcctc caacaagtca tgagcttctc cagagattat ctcctaaccg
     1561 ttctgagcca gagattaagc attgatgtga ttttatccta tattcgccat atttttgaac
     1621 ttcccatgtc tttctttgcg acacgtcgta caggagaaat catttcacgg ttcacagatg
     1681 ctaactctat tatagatgcc ttggcttcta ccattctttc tctttttctg gatgtttcta
     1741 ttctgattct tgtaggggga gtcttgctgg cacaaaaccc taatctcttc ctcctttctc
     1801 ttctttccat tcctatatac atgttcatca tcttttcttt tatgaaacct tttgaaaaaa
     1861 tgaaccatga tgtcatgcaa agtaattcta tggttagctc tgccattatc gaagatatca
     1921 acgggattga aactataaag tcgctcacga gtgaagaaaa tcgctatcaa aatatagaca
     1981 gcgaatttgt agattatttg gaaaaatcct ttaagctcag taaatattct attttacaaa
     2041 cgagtttaaa gcagggaaca aaattagttc tgaatatcct tatcctatgg tttggcgctc
     2101 aattagtcat gtcgagtaaa atttctatcg gtcagctgat tacctttaac acactttttt
     2161 cttactttac aactcctatg gaaaatatta tcaacctcca aaccaaactc caatctgcga
     2221 aggtcgctaa taaccgtttg aacgaagtct atctagtcga atctgaattt caagttcaag
     2281 aaaaccctgt tcattcacat tttttgatgg gcgatattga atttgatgac ctttcttata
     2341 agtatggttt tggacgagat accttaacag atattaatct cacgattaaa caaggagata
     2401 aggttagcct agttggagtt agtggttctg gtaaaacaac tttagccaaa atgattgtca
     2461 atttctttga accctacaaa gggcatattt ccatcaatca ttaggatatt aaaaacattg
     2521 ataaaaaagt cttgcgccgt catattaatt acctacccca acaagcctat atctttaatg
     2581 gctctatctt ggaaaactta accttgggcg gtaatcatat gattagccaa gaagatattc
     2641 taagagcttg tgaattagct gaaattcgtc aagacattga aagaatgcct atgggctatc
     2701 aaactcagct ctctgatgga gctggtctat caggaggaca aaagcaacga atagccctcg
     2761 ctcgtgctct tttaactaaa tctcctgttt taatactaga cgaagctact agcggtcttg
     2821 atgtcttgac tgagaaaaag gttatagata atcttatgtc cctaactgat aaaaccattc
     2881 tctttgtagc ccatcgtctc agtatagccg aacgaactaa ccgtgtcatt gttcttgacc
     2941 aggggaaaat cattgaagtt ggtagtcacc aagagttaat gcaagcgcaa ggattctacc
     3001 atcatctatt caataaataa ggagaatgtc atgaatccta atctttttag aagcgtcgag
     3061 ttttatcaga gacgttacca taactatgcg acagtgttaa ttatacctct ttcattacta
     3121 tttactttca tcttgatttt ctcccttgtt gccacaaaag aaattactgt tacttcccaa
     3181 ggggaaatca cccctacaag tgtcattgca tctattcagt cgaccagtga taatcctatc
     3241 cttgctaatc atttagtggc aaatcaagta gttgaaaaag gggacttact catcaaatac
     3301 tctgaaacaa tggaagaaag tcagaaaact gccttagcaa ctcaattaca aagacttgag
     3361 aagcaaaaag aaggacttgg aattttgaaa caaagcttag aaacaacgac tgatcttttt
     3421 tctggcgagg atgaatttgg ctaccataat acctttatga attttactaa acaatcccat
     3481 gatattgaac tgggtatcac aaagactaac actgaagttt caaatcaagc taatctttcc
     3541 aatagcagtt catcagctat tgaacaagaa attacaaaag ttcaacaaca aattggagaa
     3601 tatcaagagt tgagagatgc tatcataaat aacagagcac gcttaccaac tggcaatccg
     3661 caccagtcaa ttttaaatcg ttatcttata gcctctcaag gacaaacaca aggaactgca
     3721 gaggagccat ttttatctca aattaatcaa agtattgcag gtcttgaatc atctatcgca
     3781 agcctcaaaa ttcagcaagc tggtatcgga agtgtagcaa cttatgataa tagtttagca
     3841 accaaaattg aagtactccg cactcagttt ttacaaacag cctcacagca acaactaacc
     3901 gtggagaatc aattaacaga attaaaagta caactagatc aagcaacgca gcgcttagga
     3961 aacaatacct taaccgctcc aagtaaaggt atcgttcatc tgaacagcga atttgaaggt
     4021 aaaaatagaa ttccaactgg tacagaaatt gctcaaatat tccctgtcat cacagataca
     4081 agagaagtac taatcactta ctacgtatct tctgactatc tacctctact agataaagga
     4141 caaactgtaa gattaaaact ggagaagatt ggaaatcacg gcaccaccat catcggccaa
     4201 cttcagacaa ttgatcaaac tcctaccaga acagagcaag gtaatctctt taaattaacc
     4261 gctcttgcaa aactatctaa tgaggatagt aaactcatcc aatatggctt acaaggtcgc
     4321 gtcactagtg taactgcaaa gaaaacatat tttgattatt tcaaagataa aattttaacc
     4381 cattctgatt aattttcaga taacactcta taactattta ttatcttatc aaaaaggaga
     4441 atcataacat ggataagaaa caaaacctaa cttcatttca agaactaaca actaccgaac
     4501 tcaaccaaat tacaggtgga ggactgtggg aagatatctt atacagcctt aatataatta
     4561 agcataacaa tacgaaagga cttcatcatc caatacaact ataaaaaata agaccgagta
     4621 acaagaactc tcggtcttat ttttttcatc attctgtagg tatcatagta agcacctgac
     4681 gaaagacttg atcttgacag gtagtattta aactggcatt gggataactt tccacaatct
     4741 tcataacggt atagagaccg acacctctct cctccccttt agaactaact ccaaaggaga
     4801 agatttcaga aatatctatg ccctcttctt tgatggaatt ttcgatgatg aaggtctcct
     4861 gtgctccact ttttaaaaag gcaattgaaa catgaggttg accggcctct gcactcgctt
     4921 caatagcatt atcacaaagg atagacacaa tggttagaaa atcaagcagt ctcatcccct
     4981 caacctgaat ctcttcagga acttcgacat taaagacaat gtccttttct ctagctttta
     5041 taaattttcc agctaggaga cttttgaggg cacgatcccg aacattcacc aatcggccaa
     5101 ggtcatattt attgtcctgc aattttttac tagaatcctt taagaccaag tcatagacct
     5161 cttttatctg ctccatatcc tcctcttcaa tacccagacg taaacttgtc aagaggttgg
     5221 tgtagtcatg gcgaaaactc cttacttcct tgtaaagttc ctctatatgc cgactatagc
     5281 gttccatatc tctatagcgc aagacctgct cttggtccag tctatcatgg agtttgtcct
     5341 tcaaataggt atccaatttc ttgataaccc ccataaaaaa taggaggtaa aacactagga
     5401 tgagatggcg aacagtcgtt gattgaatac cttgctcata ttcaaagtaa gacagacttt
     5461 gtatcaccaa atagtaagcc cccattatcc agttaatctt agtcagggac ttttgaaaac
     5521 ctgtatctag aatctccctt ctcaaactag taaaatcata gtccaaccat ttcaaaaagg
     5581 ctagagaaat gaagaaattg aaaattatta tacataaccc agtaaatgag tagccatcat
     5641 atacttgctc ttgtcccaaa aatggaagca caaaatagga gactcctcta taaaagagat
     5701 tcaccaatat cattggaaag agaccataaa agaaaaggag ttttttagga agccctctta
     5761 acaataagaa agacaagcct atgccgtaca agggttccat aaaataagat aggtaaacat
     5821 ttcctatcat atagccaatc attacaaaaa caaaggccaa cagtatcttc aaaagaaagg
     5881 ccttaaaaat cctctcaaaa gtgagaccaa ttccatctac cttaaagaaa atgacaattt
     5941 ctagcccatt agtaataagt gtatacaata taatccaaaa aatatacata aatttcctag
     6001 ttcagtgtaa gttattaata gcctcagaca cttccctgac cttataacgc gcgatcagac
     6061 agcttccacc attgggaaag aaaaggagtt tttctttctt atccaaatgc accacatttg
     6121 caggattgat gagaaaagag cgatggcact gcaagagacg gggttcctgc ttaaaaacct
     6181 cctctaaact cgccgtaaat tctagcctgt ccgtcttggt atagagaata acacgatggg
     6241 gtcttgggga tgtttcgaga tagtaaacct ctttgaaagg atattggaat tgggcaaatt
     6301 ttgatttaaa gtaaaagcaa tcttccgcca gacttttact atcttgacta ttggcataga
     6361 ggagggctgt ctcgatacga gattcaaact cctctgccga aagggcctta tcaatgtagt
     6421 ccaaagctga cacttggtag cgaaaggaca gaggcataaa ctccgagtga gtcgtcacaa
     6481 agacgattag ggcataaggg tcttgttccc gaatctttct agccacttcc agtcccttca
     6541 tctcttcatt tcgaatctca atatccaaaa agaatagctg atgggccccc ttctcatgca
     6601 cctctgccag cagttggtcc ggcttgccaa atacctcaaa agagctagga atgatatgat
     6661 gtgctttcaa aagtttctca atcgtcgttt caattctagt ctgttgggaa aaatcatctt
     6721 ctaaaacaaa tattctcatc ttcttactct ccctctttca accatttttg acgtatttct
     6781 ctatagcgac gtctggcata cctgacagca tattgacctt cttctccgag aaaaaggatt
     6841 ctttcttgaa aatcaatcga ttttaattta tcaagattaa ccaaacaatt tcgatgacat
     6901 ctcatcaaag tttccccaca ttggttctca agattactta aattttgaag catattaaaa
     6961 ctagcttttt ctgtaacaat ctgtacggta tgggctttag ttggatgtgt ttggatatag
     7021 tagatatcgt cgatgtttac tttatagact gttttctgtg tctgaataat catatgtttc
     7081 attggattct cctcctaaga aaagaataac agaaaagatc tagcccaagc acacccaatc
     7141 ctaaacagtc tttgaaaact cctaaaagga ttattttcta caacatcatg atgagcttac
     7201 aactatttta tcataaaatt cactcagcgc aattcaagac atttcaatga caattaaaga
     7261 tttgaataaa aaaaagaatt aaaagtgata aactaacagt atcaaaacac agttgccaga
     7321 agtaagactg gcacccagat taaaggaggc attcccatga cagatacaga ccccatcaaa
     7381 agagctcata ctttgattac tgacttaaac aaagcctacc aagcatgcaa acaggcaagc
     7441 gctgacgacg tccgctttca ggagcaatta aactctattc ttggttttct agccaaggct
     7501 gaaacagtgg ataatcgatt cttgattgaa ctagaaaaat tttaccagac ttccagtctt
     7561 ctcatgggac tcagcgctct tgatccagat gctccaactc gtgccgcttg gcgggcctat
     7621 gaccgcttcc actttgacca agtcaagacc aagttaatac tcaatgaaaa tcaaagagca
     7681 aactaggaag ctagccgcaa gctgtacttg agtacggtaa gacgacgctg acgtggtttg
     7741 aagagatttt cgaagagtat aagtctctac ggaccaacca ttatcctgta gtaacaaaaa
     7801 agaagctgag acagactgaa ctcaacttct tttttagtgt cgtatcagca atgttagtcc
     7861 tgcatctgac gttttacctg ataaggcaaa tacaagacta gtaaaaccaa accagctcct
     7921 agtaaggcta gaagggccag tttttcttgg aaggtaatca acccaacaac taattccaca
     7981 agtaaaacaa aactggtcaa tcctcgaact acctcctgta agcctttttc cttttgcccc
     8041 ttgtccagcg gaaagagttg ggtcaaatac tggtagtcaa aggcatgata gagggccagc
     8101 aactggaaga gcaagaggta gttaaagaga actaccactg ctgtcgcaat ccaagcttgc
     8161 tcgataaaaa cctgcgccag tacggaaagt aagagaagac gaagactgag agcaaagagg
     8221 tcgccatttc gcagataaga acgcagatag agattttgcc aaatcttccc aggcaccttc
     8281 tgaacagcct ttaagataaa gtccagatag gcacgacgct taacgctgtt tgaaattccc
     8341 ttgacctgcg taaagagggc aaagaaacga agcaagactt gcttacgctt gctttcttgg
     8401 gaaatgacat agtcccagtc cagcccagtt tcagtgaaaa atttgctggc cttttgacga
     8461 aagtggaaat attttcctac ccccaataaa agcacataga gcagaaaaac tggcaagcca
     8521 taacccattg ctaaaaataa aggcgcaaat aacagcaaga aaagggtctg tacaaagagc
     8581 caaaagacta gggaaatgcc agtttgacgc ttgagatgga gcttgatttc ctcttctcca
     8641 actaagagaa agagcttgtc tggagcctcc atataggtgg caattcctcc ccaaagtaaa
     8701 agtaaaacag acgtaattcc tacaaacaaa aggataggcc aatgattttc aggaaaatgt
     8761 tgtaagagtt gactgtactg gtaggctaga aagcccaaca ggacaagcag gaacaagaca
     8821 aagtggtcat tgagcacata gcgcagataa ccaagacact ccttacgaaa ggcctgcttt
     8881 ctctttaaaa acaagtcttt catagatcct cctctttggt cagagccaag taaatatcat
     8941 tcaaactagc ctcaggcata tcaaaggctt cacgtagttg caggagattg cctttggcac
     9001 gcacctctcc cttgtgaaga atgacaaagg catcacacat cttctccgcc gaatccagca
     9061 cgtgggtact catgagaata gacttgccct tttgcttctc cacttccaaa agctgaatca
     9121 aatcagaaat agccagcgga tcaagaccaa ggaaaggctc atccacgatg aaaagacttg
     9181 gatccaccac aaaagcacag ataatcatga ccttctgctt catccctttt gaaaaatgaa
     9241 cagggaacca gtctaatttc tgttccaaac ggaacatttt taacaagggc tctactcgtt
     9301 cgaaagccac tttttgctca ataccgtaag ccatagcaac cgtttcgata tgctctctga
     9361 gggtcaattc ctcatacaga ctaggcgtct caggaatgta gccaatctgc ttgcggtagc
     9421 tagtcgcatc tccttgcaga gtcaggccat tgatattgat ggagccacta taaggtgcca
     9481 acagaccgat aatctcattg atcgtcgttg atttcccagc accattgaga ccaatcaaac
     9541 cgaccaactg cccactttca acagtaaagg acacatcttt caaaacagga acatgaacat
     9601 agccacctgt caggttttta atttctaaca tattttctcc aaatctggta taatgtagct
     9661 atattatatc aaaattcagt acagtagagg tagattttat gtcagattgc attttttgta
     9721 aaatcatcgc aggggaaatt cctgcttcaa aagtatatga agatgagcag gtccttgcct
     9781 ttcttgatat ctctcaagta acactaggac acaccttggt cgtgccaaaa gaacactatc
     9841 gcaatctttt ggagatggat gctacgagcg ccagccaact ctttgcccaa gtaccaaaag
     9901 tagctcaaaa agtcatgaaa gtcactaagg ctgctggtat gaatatcatt tccaactgtg
     9961 aagaagtcgc tggtcaaaca gtttttcata ctcacgttca ccttgtgcct cgctacagtg
    10021 ctgacgatga cctcaagatt gattttatcg cccacgaacc agactttgac aaacttgctc
    10081 aagtcgctga aaccatcaaa aacgcttaag gagttgctat gaaattatcc aacctactgc
    10141 tatttgcagg agctgcagcc ggaagttatc tggttacaaa aaatcgccaa accatcacag
    10201 atgaagtctt gaataccact gaccgcgttc aagctatcaa ggacgatgtg gatattatcc
    10261 aaaacagcct gcaaatcatt aaccagcaaa aagaacttat caaggaatac caagaagact
    10321 tgacttacaa gtttaaggtc ttggaaaagg atatccagac tagactagct gtgataaaag
    10381 aaatgcaggg aactgaagat aagtaaaaag agcccgacgg ctctttttta aaacgtaaac
    10441 aagttatagt gaattgaatt tagaatagca catcatagtt tctaaagcat tgttagagat
    10501 tactttaaaa tcctcttatc aatttgttca tattctattt caatctacta tatatatccc
    10561 atcaactatg catcataatt taggtaactc atactcaata aaaatcaaaa agcaaactag
    10621 aaagctaggc acagactgct caaaacaccg ttttaaggtt gtggatagaa ctgacgaagt
    10681 cagctcaaaa cactgttttg aggttgtgga tagaactgac gaagtcagct caaaacactg
    10741 ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat acccatgaca agccgacgct
    10801 gacgtggttt gaagaaattt ttgaagagta tcattcacca tttcacaact aaatcgaaga
    10861 ctttctgccg taatgaaaac acctgaaaca gcttggtttc agctgtccgg aaactttaag
    10921 acttaggttc aaagtttagg tatggaactt cgaaggaggt cgctaccgtc cgtcattact
    10981 taggaaagtc ttaaaaaatc tataaagtaa aaagagcccg acagctcttt ttgtttatac
    11041 tcaatgaaaa tcaaaaagca aactaggaaa ctagccacgg gctgctcaaa acactgtttt
    11101 gaggttgtag atacgactca catatatacg gcaaggcaac gctgacgtgg tttgaagaga
    11161 ttttcgaaga gtattattct ccatcaaagg catcttttat atggtcaaag aagccttttt
    11221 tctttggatt tactttcaag tcaccagcag tcgcgaattc tttcaaggct actttttggc
    11281 ggtcgttcaa gcctgtcggt gttacgacat taacagtaac gtattggtca ccaactgcac
    11341 cgccacgaag gctcggtgcc cccttactac gtaggcggaa tttcttacca gtctgagttc
    11401 cctctggaat aaccaattca acatcaccgt aaacagttgg aatatctact gtatcaccaa
    11461 gagccgcttg gacaaagttg aggttgagat tgtagaagat agtcgttcct tcacgttcaa
    11521 acttgtcgct agcttctaca gaaactacta catacaagtc accataaggt ccaccgttaa
    11581 agcctgcttc accttgacca gcgaggcgaa tttgttgacc tgtttccaca ccagcaggga
    11641 ttttcacatg tacgctatga gcttgtttct catgacctgt tccatgacag gttgtacatg
    11701 gatatttgat ttcttttcct cgaccgtgac agacatcaca ggttacttgg cgacgcatca
    11761 taccaagagg agtctgcgta tcgacgttaa tgacaccagc gccatgacag cgtccacaag
    11821 tgactggact tgtccctggc ttagcaccag agccattaca tgtacgacag ccagcttcac
    11881 gatgatactt aacttccttc tcagttccga agatagcttc ttcaaaggtc aaattgacac
    11941 gatactggag atcatctcct tggcgaggag cgtttggatt gcgcgaagaa ccgcctccgc
    12001 cgaagaaact tgagaaaatg tcctcaaaac caccgaagcc acctgcccca ttgaaaccac
    12061 cgaaaccacc agctccacca aaaccaccat tggcgcctgc agcaccatac tggtcatagg
    12121 cagcacgttt ttggtcgtca ctcaaagtct cataggcttc ttgaacttcc ttgtacttgt
    12181 cctcagcacc aggctccttg ttgatatctg ggtgatattt tttggaaagc ttacgataag
    12241 cctttttgat ttcgtctgcc gaagcgtttt tggatacccc cagacgatca taaaattcag
    12301 tattgttcat acaagatacc aagaccgtaa aattcgactg aaaaatagga aatctgacgc
    12361 tggagcgacg ctcctagaca gatttctctt ttttccgaga atttaggtcg ggttcaattc
    12421 ctttctttta tattgatgag ataatactcc agccactcgg ccctatccct ttttaccgaa
    12481 aaacagaggc tgggttacaa cctctgtggt tagattattc atttgaaata aaaatggttg
    12541 tattatctct agtagtaatc ttcaaagacc ttttagctaa atcaaactca aatttattat
    12601 agtgtgggtc ttgtgtttta tataggtgta actcctgaca tatatgatcc gaaaagtaaa
    12661 tcataacatc tttaaacaca gaagtgtggt catatttact cttaccaaca gctacttctg
    12721 taaattcttt ataaatgaca tttccatttc tttccacagt caccagcatt tctgttggat
    12781 tataatccaa attaaataat tattcaaaaa actttatctt ttcatgataa tctgcaatgt
    12841 cagaaagatt atttttatta acactcataa cactagcccc ttatttttca gtaaactctc
    12901 cgtctacgac gtcatcgcct gcgtttcctg ttgcttgtgc gccttctgct ccttcttgag
    12961 cttgttgcgc tgctgcggct tgttcgtaga gtttcacagc aaggccttga gctttttcgt
    13021 tcaacgcttc aagtttcgct ttcatgtcgt ccaagttgtt gtcttcttga gctttcttaa
    13081 ggtcatcaag ggcagcttgg gcagcgtcac gttctgcgtc gaagccttta ccttcagttt
    13141 ccttgattgt cttttcagtc gcaaagattg cttggtctac ttcattacga aggtctactt
    13201 cttctttacg tttcttatca gcttcagcgt ttgcttcggc atctttcatc atgcggtcga
    13261 tttcttcgtc agtcaaacct gagttcgatt ggatgacaat agtttgttct ttttgagttc
    13321 caaggtcttt ggccttaaca gacacgatac cgttcttgtc gatgtcaaat gttacttcga
    13381 tttgaggaat tccacgaggt gcagctggga tatcagtcaa ttggaagcgt ccaagagtct
    13441 tgttatctgc tgccattggg cgttcacctt gaagaacgtg gatatcaacg gctggttggt
    13501 tgtctgctgc tgttgagaag acttgtgatt tagatgttgg gattgtagtg ttgcgatcga
    13561 taagttttgt aaatactcca cccattgttt cgataccaag tgacaatggc gttacatcaa
    13621 gaaggacaac gtccttgaca tcaccagtaa tcacaccacc ttggatagcc gcacccatag
    13681 caactacttc atcagggttt actgatttgt ttggttcttt accagtttca gctttaacag
    13741 cttcaacaac ggcagggata cgagttgaac caccaacaag gataacttcg tcgatttctg
    13801 acaagctcaa acctgcatct gaaagggctt gacgaactgg aacttttgta cgttcaacaa
    13861 ggtcacgagt caaatcatca aatttcgcac gagtcaaagt catttccaag tgaagaggtc
    13921 cagcctcacc tgcagtgata aatggcaagc tgatttgtgt tgaagttaca ccagaaaggt
    13981 ctttcttcgc tttttcagcc gcatctttca aacgttgcat tgccatcttg tcagtagaca
    14041 agtcgatacc gttttctttc ttgaattctg ctaccaagtg gtcaatgatt ttttggtcaa
    14101 agtcgtcacc accaagtttg ttgtcccctg cagttgacaa tacgtcgaag acaccgtcac
    14161 ccaattcaag gatagagacg tcgaatgtac caccaccaag gtcaaatacc aagatttttt
    14221 cttctttgtc agtcttgtcc aaaccataag caagagctgc tgcagttggt tcgttaacaa
    14281 tacgttctac ttcaagacca gcaattttac cagcatcttt tgttgcttga cgttgagcgt
    14341 cgttgaagta agccggaact gtgataacag ctttggttac tttctcacca aggtagtctt
    14401 cagcgtagcc tttcaagtat tgaaggatca tagctgagat ttcttgtgga gtgtattctt
    14461 ttccatttgc agaaactttt tcagaagttc ccatcttaga tttgatagag ataactgtat
    14521 ctgggtttgt gactgcttga cgttttgcag catcaccaac gatgatttct ccgtttttga
    14581 atgagactac agatggagtt gtgcggtttc cttctgggtt tgcgatgatt ttgctttcag
    14641 ttccttcaag aactgcaact gctgagtttg ttgtacctaa gtcaataccg ataattttag
    14701 acatgtgttt ttctccttgt tagttaattt tctatttttc tttttgatac tcttcttaag
    14761 tggcgacgcc gtcagagctt gacttcgtca atctctttga ctaaactttg agcctaaggt
    14821 ctcaaaattt gcgcaaatag cgccacagcg aagagtatcg tctttggttc gcttcgctca
    14881 ctattacaaa gccaaacata ttttatcttt cttcatagtt tattgtcgtt tcggacaagt
    14941 tttctattat gtaaattgcg acacgaggag tcgaaatcga ttttatttcg acgacgagtt
    15001 gctttagcta ccgtcagaat tgccgaatcg aacacgccct aagctctgag taaaaaagat
    15061 agattttctt gtgttcatcg aacacttcgt caatctccta tttttactgc gagcttttta
    15121 cgggctttgt atcttagtta tacaccacta ccattgctgg gcgtaggatg cggtcatgga
    15181 gtttgtagcc tttttgaaag acttgggcga tggtatctac tgggtgttca tcgtctgctg
    15241 ggagagtttg gatggccata tggtagttat ggtcaaattc gccatctgct gcgatttctt
    15301 caattccttc ttctttcaaa gcgtgaatca agctttcttg caccatcccc aagcccttct
    15361 tcacatcatc tgtcaaacct tcaactgcaa gtgcacgctc aaggttgtca agagatggta
    15421 agattgcttt tgccaagtcc tggctacgat aacgttgcaa gttttgacgt tcttcgttgg
    15481 cacggcgttg gatattttgc atttctgcat gagcgcgaag atatttgttt tcgaactcat
    15541 ctgcacgttc atttgccaag tccaacttag acttttcagg agttgtttct tcagctgttt
    15601 ccacaacttc ctcttcttga acttcttcta cttcttcatt ttttatatct tgggccatgt
    15661 tcgcctcctt taatgatttc aatcttaatg tacttcgtaa tgattactgc tgaggtagcg
    15721 gtaaaaatct gtcaacttca tagtcaaaac acggttgacc acattgactt gattgattag
    15781 ctgttggtaa tccagattaa ctggaccgat aatggctaga attccaactc ctcgataagg
    15841 aatgaggaac ttactactaa tcaccgctag gtcagctaaa caggactctt gaccgtctgc
    15901 aacacgaaca ttttgcatct gatcctcacg caacccctca cgaatctcca aggccacctt
    15961 ttgcggttgg tcaaagaact gataggcttc tagattggca aaattcaaga gattgacctt
    16021 gcccgccatc acaatgtttt cgttgaacat ttccttaaag atgtgttcaa agagatcgat
    16081 gacattatcc gttgttgtaa agtaacgctg gataatctgc ggaatctccg tccgaatctt
    16141 gtagtgaata tctaaaacgg tgtgaccgag gaaacgttcc tgaatgatgc tcttcagttt
    16201 cagcaaatcc tcctgcaaga agttccttgg aatcagaaac tgactagtaa ccgttcgcga
    16261 ctcgtctagg gtaaataccg ccaaggctgt atgttgcccc aaaacaacga tatcaaaggc
    16321 tgtcaaacgt tgcctgctcg gctcaacatc cagtgccact accgtacagc cactcaggtc
    16381 tgttagcaag ttagcagcct cttgcagaat atcctccaat ttgaagaatt cctgatcaaa
    16441 ggctttgaca atctcatata cctcattttc agccagccgg tgaaaatcca gtgagtgttt
    16501 cacatagtac tgaaaaccag caacacttgg catccgaccg cttgaagtat gagccttctc
    16561 aagcaaccct tgtttttcta gttccgccat gtcattacga atggttgcac tgctagagtt
    16621 aatagactct tgcaaggctt ttgatccgac aggttcgtgc gttttggtaa agatgtcaat
    16681 aatcagattt aaaatatcct gctgacgctc tgtaaccatc tcatcactcc tctctgtctg
    16741 atcaattagc actcaatgca tccaagtgct aacttatgat tctattatac acccttaaaa
    16801 gagaatgtca agacaaaaac tcaaaaaatt agcactcttt tatcaagagt gctaaaaatc
    16861 aatctgaaga cctagaacct tgctattcat ctactcggta tttccttttt agtctgaaat
    16921 aaccatgaat tagataagaa atcagaaaag catataaaac aaaaataaga aagaaagaca
    16981 tagaaagatc ctctctaaac aaactcgtac aaacaacaag accacctaag aaagtagttg
    17041 tacaggaacg aagtctagat cgcataactt cccatttgag ccccttactc atatagactt
    17101 gatcctctgg aagtaaatca gaagacgatt tacgaagaat cgaacaagaa cctgctccta
    17161 tcaattccca acctctatct ctaaaatctt gcagttcatg cttatatttt ttaagaaatc
    17221 tagaatcata gatacggtag atgacatcgt ctggttgaca ttggtcaaaa tagaacaaac
    17281 caaaacgact cgttctatac ctccaacctt tcaaatgcat ctcatgtaaa tattcttctt
    17341 ccttgtccaa atcaacaatg gtgaaaatcc gaaattctac tctgctattc attgtcttac
    17401 cccaaaatta gaaaacatgc ctggcgttat ttattagata attctttcca cttttgactc
    17461 aatctccaaa aaatataaga aatctgaatc gcaaaaacta tcaataaaac ccaatctatt
    17521 atgaaaatca aaaacacttt ccaactgaaa gaactacctc cagtgacaaa ctttgagaaa
    17581 aacggcagta gagctaaaaa gagaagtaaa ataggaagca tccgcattgt taaaatccgt
    17641 ttggcataaa aaaatcttta tttaaacgaa aatattatag caaaatttac gccagttttt
    17701 gaacggctga tgtagatatt ttatactttc aaaatgttta aatgtgatta tttatttttg
    17761 aaaaatagct caccagcccg actgaaagtg cttatagaat gataataagt cgcctgccga
    17821 aaacagcgga aaatagcggt gttatgcgga gataatctga cgcgatgcga aagtatattg
    17881 catacttatt ttcaacaatt tagcagagta tttttataag tgtgatataa tagaagtata
    17941 atttgttctg atagtttatt ttatggagaa gtagattttt agaatgcgga gggttcaata
    18001 tggttgagtt tataaagtct aagaaagaaa tgagtgagga ggatattaaa gcaaatttca
    18061 tcactcctgc tattgtatcc aaaggatgga aaaatggtga gcatatcgct tacgaagaat
    18121 acttcactga tggtcgaatt gaggttagag gagataaggc tcgtcgtaaa gaaggaaaaa
    18181 aatcagacta ttcactgtat taccaatttg gaactcgaat tgcaattgtt gaggcaaagg
    18241 ataataaaca cagcgttcga gcaggattac aacaagctat tgaatatgga gagattttag
    18301 atgttccatt tgtttattct tcaaatggtg atggctttat tgaacacgac cgtatcacga
    18361 gagaagaacg tgagctggag ttagacgaat tccctactcg tgaagaatta ttttctcgta
    18421 tgacgaagga aaaaggattg acgtacgaaa ttacagaagc tatctcaact ccatactata
    18481 cagacgcctt ctcaatgaaa acgccacgct attatcagca aatagctatc aaccgtacta
    18541 ttgaaacagt tgccagagga caaaaacgag taatgtttgt gatggcaaca ggaacgggga
    18601 aaacgttcat ggcttttcaa attattcatc gccttcgaaa agctggtttg gctaaacgag
    18661 ttttattctt agcggataga aacatcttag tagaccaaac gatggctgaa gactttaagc
    18721 cattcgaaaa ggtaatgacg aaaattacac caaaactttt gactgctcct gaaaaattaa
    18781 attcttttga aatttatcta gggctttatc agcaactaac tggtgaagat ggaactgaaa
    18841 cacattatca aaaatttgac aaagacttct ttgatttaat cgtaattgat gaagcgcacc
    18901 gtggttcagc taaggaaaac agtaactggc gtaagataat tgattatttc agttctgcga
    18961 cacagattgg gatgaccgct actcctaaag aaaccaagaa tgcttccaat acggaatact
    19021 ttggtgagcc aatctatact tatagtttaa aacagggaat cgaggatggt tttttggctc
    19081 catatcgtgt tatgagggtt aatttagatg tggatgtgga tggttatcgt ccagaaactg
    19141 gaaaagttga tactaacgga ca
//
LOCUS       DAVKAU010000036        18873 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVKAU010000036 DAVKAU010000000
VERSION     DAVKAU010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.036"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(100..753)
                     /gene="phoU"
                     /locus_tag="VWX48_001437"
     CDS             complement(100..753)
                     /gene="phoU"
                     /locus_tag="VWX48_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9172046.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(765..1523)
                     /gene="pstB"
                     /locus_tag="VWX48_001438"
     CDS             complement(765..1523)
                     /gene="pstB"
                     /locus_tag="VWX48_001438"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9172047.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(1536..2339)
                     /gene="pstB"
                     /locus_tag="VWX48_001439"
     CDS             complement(1536..2339)
                     /gene="pstB"
                     /locus_tag="VWX48_001439"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9172048.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLSQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(2350..3234)
                     /gene="pstA"
                     /locus_tag="VWX48_001440"
     CDS             complement(2350..3234)
                     /gene="pstA"
                     /locus_tag="VWX48_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9172049.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(3224..4141)
                     /gene="pstC"
                     /locus_tag="VWX48_001441"
     CDS             complement(3224..4141)
                     /gene="pstC"
                     /locus_tag="VWX48_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9172050.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(4141..5019)
                     /gene="pstS"
                     /locus_tag="VWX48_001442"
     CDS             complement(4141..5019)
                     /gene="pstS"
                     /locus_tag="VWX48_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU9172051.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(5593..6897)
                     /locus_tag="VWX48_001443"
     CDS             complement(5593..6897)
                     /locus_tag="VWX48_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU9172052.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKKPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLQETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(6898..7671)
                     /locus_tag="VWX48_001444"
     CDS             complement(6898..7671)
                     /locus_tag="VWX48_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU9172053.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(7661..7939)
                     /locus_tag="VWX48_001445"
     CDS             complement(7661..7939)
                     /locus_tag="VWX48_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU9172054.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(7939..8340)
                     /locus_tag="VWX48_001446"
     CDS             complement(7939..8340)
                     /locus_tag="VWX48_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU9172055.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(8550..9167)
                     /locus_tag="VWX48_001447"
     CDS             complement(8550..9167)
                     /locus_tag="VWX48_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU9172056.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(9157..9930)
                     /locus_tag="VWX48_001448"
     CDS             complement(9157..9930)
                     /locus_tag="VWX48_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU9172057.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(9941..10678)
                     /locus_tag="VWX48_001449"
     CDS             complement(9941..10678)
                     /locus_tag="VWX48_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU9172058.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(10683..11813)
                     /locus_tag="VWX48_001450"
     CDS             complement(10683..11813)
                     /locus_tag="VWX48_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU9172059.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(11897..12286)
                     /locus_tag="VWX48_001451"
     CDS             complement(11897..12286)
                     /locus_tag="VWX48_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU9172060.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(12302..12685)
                     /locus_tag="VWX48_001452"
     CDS             complement(12302..12685)
                     /locus_tag="VWX48_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU9172061.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(12686..13474)
                     /locus_tag="VWX48_001453"
     CDS             complement(12686..13474)
                     /locus_tag="VWX48_001453"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU9172062.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(13467..14402)
                     /locus_tag="VWX48_001454"
     CDS             complement(13467..14402)
                     /locus_tag="VWX48_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU9172063.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(14532..14708)
                     /locus_tag="VWX48_001455"
     CDS             complement(14532..14708)
                     /locus_tag="VWX48_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU9172064.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(14848..15555)
                     /locus_tag="VWX48_001456"
     CDS             complement(14848..15555)
                     /locus_tag="VWX48_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU9172065.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            15706..16734
                     /gene="queA"
                     /locus_tag="VWX48_001457"
     CDS             15706..16734
                     /gene="queA"
                     /locus_tag="VWX48_001457"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU9172066.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(17395..18522)
                     /locus_tag="VWX48_001458"
     CDS             complement(17395..18522)
                     /locus_tag="VWX48_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9172067.1"
                     /translation="MNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRFEKDETKYRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEKVTVD
                     RKEATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVIVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNTSGELAVNTSIDGYRVNDNGEWVR"
BASE COUNT         5596 a         4342 c         3432 g         5503 t
ORIGIN      
        1 caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa ggagccatca
       61 gttgatttca agctcctttt tatacagaat taaactattt tatagttcga caatcttacc
      121 tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga tacgctccaa
      181 gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat ttttcttaat
      241 ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct catccatgga
      301 ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg ctgcttcaac
      361 aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg gaatgcgctc
      421 ttcccccttc atacggatgg ttgcctgagc aatggctaca gcgtgatccc ccatacgctc
      481 cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag agactggttg
      541 ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt catttacttc
      601 tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa aagcacgtac
      661 cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt tatgtaattt
      721 ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc aaattttcct
      781 gtaatatagt cttccgtttc cttgtgttgg ggattaagga acatctgctt ggtatcatta
      841 aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg tgaagcttgc
      901 tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata caaggtttcc
      961 tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa gaggatgatt
     1021 ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc acctgacaat
     1081 ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc accttgcaag
     1141 gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat acgaagcccg
     1201 tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa aaccattccg
     1261 atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg accattgtac
     1321 accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt gagagacttg
     1381 aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc cttaggttgg
     1441 aaagataggg aaacactatt caaagccttc tttttattat aataaacgga caggtctgat
     1501 acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc agatacatag
     1561 tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc atactcaatc
     1621 aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg ctgcatatta
     1681 tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc ttctagttgc
     1741 atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat atctggctta
     1801 acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa ggtcaaggct
     1861 gacttgtgga gatcgtcttt aacctgatcc caaagggcag cctgactaag ggaggtttct
     1921 acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc aaaggtaata
     1981 ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc aatgtgttta
     2041 cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata gagaatctgc
     2101 ccagttactt tagcaatatc aatggtatca ttcatgcgat tgagactgcg taagtaggta
     2161 gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc aaattgcata
     2221 tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt agtagaaagg
     2281 gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata tgttgacatg
     2341 gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact tacgagctcc
     2401 aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg atacaatggt
     2461 tccatctgga atagtgcctt cactattgac tttccagata tggacagcca aggtttctgc
     2521 ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag accagtcaag
     2581 agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa agatacgacc
     2641 agatgccaaa acgacacccg ttacaatacc tggaagcgct tctggaataa caacatgaac
     2701 cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg tatggtgaac
     2761 gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga ctgtcaaggc
     2821 caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga tcaagtaacc
     2881 aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag tccgcacaaa
     2941 gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc ccatagaaag
     3001 aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa gctgaatgcc
     3061 aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc aagagatatg
     3121 gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca caatgatgct
     3181 agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc gcataatttt
     3241 tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa ctcatcaaga
     3301 gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg acagtgttcc
     3361 caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag gaagttggga
     3421 taacagctga gtttccgaca accatctgga tagctagagc ctcaccaaag gcacgcgcca
     3481 tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc acacgccaga
     3541 tagtctgcca gcgagtggct cccatagcga aactggcttc acgataataa cgaggaaccg
     3601 cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca aagaggacgg
     3661 aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca aagggaacga
     3721 cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg agttcaatag
     3781 ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact gctgcaccaa
     3841 tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa cccaaaatca
     3901 taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa agaaagtcaa
     3961 agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg aaaaccaaaa
     4021 tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct tttcctaatt
     4081 tctccagacg agaattcttt gatggaagca acattttctt agctaattct tcttgattca
     4141 ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa ccttcatttc
     4201 cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat ccgagagaac
     4261 aaaattgaga aattctgcag ccaactcatt gggctgcccc aatgtataca tatgctcata
     4321 agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat agccattcaa
     4381 cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga tagctcctgg
     4441 actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac tttgcatggc
     4501 agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc cggctgcccg
     4561 attgataaca gagatgggta agtccttacc accaacctct ttccaattgg ttacctcacc
     4621 tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct ccttattgac
     4681 aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag catcaattcc
     4741 gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag actgaacctg
     4801 ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa catggatcgt
     4861 gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc caacagccgt
     4921 tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg tcagccaaaa
     4981 agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc tcgaaaataa
     5041 ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga attcttacca
     5101 aatttctgcg caattgatta tttatataat ataggctata ttactctttc ctaacctcct
     5161 tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac ccattatagt
     5221 catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactcttct tagatgataa
     5281 tccaaaagct agaaaggtat ctcaaacctc tctactctcc cagactagtt tacaactaaa
     5341 aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg ctaataacta
     5401 aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc tatggctagc
     5461 ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg gcaatcaaga
     5521 tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga ataagatatt
     5581 tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca aaacatttcc
     5641 agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc aaccatttgg
     5701 cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaacg cttcttggcc
     5761 aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag cgaaactggg
     5821 ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa tcttgagctt
     5881 ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa tctgcaagat
     5941 acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg caacttgttc
     6001 acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac ccttaaactg
     6061 tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc gagccgtttc
     6121 ttgcaggtca ataccagcta ccattccatt gatatgctct actggcaaca agtcaaaatc
     6181 atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc aggtacaggt
     6241 cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca gaatttctct
     6301 ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag catcaggttt
     6361 cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt caaaatagcc
     6421 tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat ttgtcgctcc
     6481 aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt cattggaaac
     6541 aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc ccggtgcagc
     6601 agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca ccatttgagc
     6661 agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc ctgaaacctt
     6721 cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt gctcttcttt
     6781 taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa gaaaatctct
     6841 tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa atttcattta
     6901 agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa gaggcaccat
     6961 catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca caacccgata
     7021 gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca gataggtgag
     7081 ataggtcaac aaatgccctg acaaaatctt ggcaaaacta atggccgcac ttccatagac
     7141 acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg tttccagcat
     7201 accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag gagctagggg
     7261 cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc ctttgaccac
     7321 atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca taacagcaaa
     7381 atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga cccaaacctt
     7441 gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat cctcaggata
     7501 acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc tggtcaccaa
     7561 atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt caagaatgta
     7621 ctggcctgct ttcttaacaa gctctttagc aaattcaaat ttactttcca agagaaatct
     7681 ttccttcccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag ccactaaccg
     7741 tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc gctttgaatc
     7801 ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca gcttcaacat
     7861 cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa tctagtgggt
     7921 aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt ttagttcttg
     7981 cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac cgatttgcat
     8041 acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct caatcaaatg
     8101 aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa aaatttttga
     8161 acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt gttgcaattc
     8221 ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct tatgtttttc
     8281 taaccaggcc ttagccttac gacatgatgt acagctcggt gatagaaata gtgtaatcat
     8341 gcttttctct tcttatctat actttgctac ttctattata caaaaaaata aagcgcttga
     8401 ctagggattt ttagaaaaaa agcctatttt ttcaagaaaa ataggctttt tgcgaacgat
     8461 tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat atatattttt
     8521 atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag atacagatag
     8581 ccaaagaagt tttcatagag ggcaaaaaag aggaggaagg catgaagaaa gaaggtctct
     8641 ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc atctcccaca
     8701 aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac tcccccaagt
     8761 ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag agacaaaaag
     8821 tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac tagagctact
     8881 agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcagacc agctgctgac
     8941 gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata attcatcaag
     9001 atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt taagtttagc
     9061 cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag gattgagagg
     9121 gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa aatcccactc
     9181 cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagccactt cttctgcctt
     9241 agtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag cccggatatc
     9301 agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta agtgctcaac
     9361 cgccttgtcc ataatgatgg catttggttt tccgatataa accggcttca ctcgtgtcgc
     9421 tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt ccgtcgggat
     9481 gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa gagttgctgt
     9541 ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg cagggttttc
     9601 cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt ctccgacgac
     9661 atagacagtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca aagtcgctgt
     9721 gtagacagtc gatagaggcg tatcgatatt aaaattctga gccaacatct ccttaacact
     9781 ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc gcttttgcaa
     9841 ttcatgaaca aaagtctctc cagcagggat tcggtctttc cccttataaa tggttccgtc
     9901 taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaaaccttt tttatttctt
     9961 gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca tgcttgcttt
    10021 ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact tccttgacat
    10081 acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc atgacctcaa
    10141 aaatccagtc caagtattta ctgttattga catgaccatt catatccaag tcgtaaaaac
    10201 gaacatggta atccttgctg atcggctctt ccaaggattc atacttcggt ccacggataa
    10261 gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca gcatggactt
    10321 ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc tcctgccccg
    10381 cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc aaggcttccg
    10441 tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata tcatattctg
    10501 cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact cccagttcaa
    10561 tcgattgcat ccctgaaact tgcagtgaca gcaaaatcac atctggaagt ttgatatgac
    10621 cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt aagcccatga
    10681 tcctactcca aaataaatcg ttctgctaca gtatctccca aaaagagacc tctctttgtc
    10741 atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc tctgacaatt
    10801 tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc catggaaacc
    10861 ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt ttgactcagg
    10921 tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg acgaatggga
    10981 ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc aataccatag
    11041 tattcagcat tgtcccagta catgagatta tgacgacttt caaagccggg tttggagaaa
    11101 ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat gtactcaaac
    11161 atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat ccggttcata
    11221 aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat atccaatcca
    11281 atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag agcataaatc
    11341 aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt ttcataaata
    11401 tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa ggtctggaca
    11461 cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc cgcatccaaa
    11521 tcgcctggat tggcttcaat ggtcaactct tccaagacag acaaatccaa gtttttagtc
    11581 aagccattca gtaacacctc cagttgcgga gccgacaggg ctgtcggtgt tccaccaccg
    11641 atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag cagatgctct
    11701 aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca ataataacaa
    11761 atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg catagtaatt
    11821 attataccac aaagactaga ttccagataa aaatcaccat ccccagatac atagtccgtc
    11881 cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct gagtcatcaa
    11941 gagcttcggc tttttcttgc cattgttcct tgagattatt taattgattt tttgatgctt
    12001 ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca gtgatttcac
    12061 ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc ttaacttctg
    12121 tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa tcatctagaa
    12181 aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac aaggcaagag
    12241 ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg attctccttt
    12301 tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca ccagtcttga
    12361 gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg tcattgaggt
    12421 ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc gtagccacct
    12481 tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg gtgtgatgca
    12541 aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca tcgatgacac
    12601 gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaca gctagggcaa
    12661 caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag taaggggcct
    12721 tctttcgatt ttgataaata acgatcatta taccgagacc gataaagaca actgacagcc
    12781 attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct tcgatgacca
    12841 tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt ctgagactct
    12901 tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat agagactcat
    12961 aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg ataaagccag
    13021 gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag aaattacccc
    13081 aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga aaatcccaag
    13141 tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt atcaaaccac
    13201 cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc tgactatagt
    13261 aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag ggaaaggcta
    13321 ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct tctttcatgg
    13381 tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa cgaatggcta
    13441 ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg agctatgaga
    13501 cttgtcagtc gttcgtcgaa caaacgggta gcatcaaagc ccatttcctt ggcacgataa
    13561 ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac tggaatacga
    13621 atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc aagacgatca
    13681 aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg tgaagaatcc
    13741 ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc acgaatttca
    13801 atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc cttggcaaag
    13861 atatcgacac ggtcatcggc taccaaacgg tgaccacgtt tgacaagctc aagacctgtc
    13921 tcgctcttac caattccact atctccctga atcaagacgc ccatcccata aatatccatc
    13981 aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct agataactct
    14041 ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca ttctctagca
    14101 gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc tggtgtctca
    14161 ggtagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct gatcagataa
    14221 gaccactcct tcatccccaa aagttgaatc cgctctggtg tatagtagtc aaaatagcct
    14281 gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc aagcaattct
    14341 ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac taaaaccgac
    14401 atcatttcct ccttcaaatg aattcttctc tctattatat caaattgtag gaggaagttt
    14461 cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat ttctctagcc
    14521 tttcatttca attagaattt tttacgttta cgagctactt ctgatttacg tttacgtttt
    14581 acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc agctttagta
    14641 accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg tactactgtt
    14701 ttagacattt ttttcactcc cttcaagttc aatatctatt tcattctaca cgtaaaagga
    14761 ataattgtca agcaaaaatg cggtttaatt ttgatttttt cttccattta tacaagagtt
    14821 gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg cttcagcatc
    14881 tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt tctcagtcac
    14941 tgggccagat actgttccgg caatggcttc tgctttcgac tcaccataag caaaaagaat
    15001 aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg ttgggacgtc
    15061 ttcaatcttg gcaaagaagc gagcattggc ttcgatagta gactggtcaa gttctactag
    15121 atgcgtttga ctatcaaatg gagtaccagg ctcattaaag ccgatatgcc cattgcgacc
    15181 gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt agcgttcaac
    15241 ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa atggtttttg
    15301 gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc catcaaggcc
    15361 cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac tctcaacaat
    15421 ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt gagctccatt
    15481 agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt ggttttcaac
    15541 tttaataact ttcatctttt catcctccat ttctgtctat atttattata tggtatagac
    15601 caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa acttgaaacg
    15661 tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa tacagctgat
    15721 tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa acgtgatgcc
    15781 tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca cttccactct
    15841 attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg agttctccct
    15901 gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct cctccttaag
    15961 aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct caaggtcggt
    16021 actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga attgacccac
    16081 gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt ggaaagtctg
    16141 ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga acgttatcaa
    16201 accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct tcacttcacc
    16261 aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct gactctccat
    16321 gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca cgaaatgcac
    16381 tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt caaaaaaaat
    16441 ggtggtcgtg tcatcgctgt cggaaccact tctatccgca ccttggaaac tattggttcc
    16501 aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat caaacctggg
    16561 tatgagtgga aggtcgtgga tgccttctca accaacttcc acctgccaaa atcaactctg
    16621 gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta ccaccattcc
    16681 atccaagaac actaccgctt cttcagtttt ggtgacgcta tgtttattta ttgagaaaga
    16741 atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa gaacatctac
    16801 aattgaaact ctagctagct gtagaagagg cctagtacat tgaaattaaa atgcttcccc
    16861 ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc atctatattt
    16921 tatttcagct tcctatactt tcttcgctgt ttgtaaatca aaatgcaaga cacatgagta
    16981 gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt atttcagaat
    17041 cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta tactcttcaa
    17101 aaatctcttc aaaccgcgtc aacgtcacct tggattatat atgtgactga ctttgtcagt
    17161 tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc tagtttgctc
    17221 tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa tgtacagaag
    17281 actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata gctttttata
    17341 tataattata tattcagaca tactattatc aattttgtcg cagggaggaa tctgttaacg
    17401 cacccattca ccattatcat tgactctata gccatctata cttgtattga ccgctaactc
    17461 acccgatgta tttacataat accatttacc accaacttgg aaccattgat tgactttcat
    17521 agaaccgttg ctgttgaggt agtaccatga accattaact tgtacccaac ctgttgccat
    17581 ggaaccatca gtattataaa aataccacat accattttct tgtttccagc ctgttgttgg
    17641 agcaactgct ttagctggtt ctactgctac atctgttcct tggttagatg taacagatac
    17701 aggatacgaa ggaatagatg attgctcagg aacaacaact ttttcaggtt ctctcgtccc
    17761 tctccttata cgtcttttta ccatctcttt agtaatttga cgagaagtag tttcttcaat
    17821 tgttccatca cgttcatcta cagcatagat tgtagtaaga gtaattttac caatttctcc
    17881 tacttcttga cctttatcaa gagttgggtc atcgagatat tctgtttcga ttggaatttc
    17941 ttggacaata acttggggct tggttccttt tttaacaact cttgtttgag agtcttcttt
    18001 ttgacttaaa gtactctcag ttacttgtcc actctttcca tctacatcat aagttatcgt
    18061 tgtaactgtt ttcccattct ttcctagagt aatctcttgc tcctgtcctg cagaaaggtc
    18121 attgtctgct tcatatttag tagcacatgg aacaagaact tcttcaacct tgcttttagc
    18181 tggaactttg ataactgtat ccgtggcttc ttttctatca acagtaacct tttcggtaac
    18241 atgaccagtc tctggattaa catcgtaggt ccttgtcgtg gttacatagc catcctctcc
    18301 gtcaattgta acaggatttt cactacggta ttttgtttca tctttttcaa aacgaattcg
    18361 cgtacttgaa attttcttgg ttactacctt aggtttagtc gctactttta caataatatc
    18421 cccattgtca gcgtcatcat actctattcc ctcttcttta tctctagtat catctctgac
    18481 atattgaatc ccatcagcag catgagcaaa acttgtattc agattcctcc taaaaataaa
    18541 gttagcccga ttaccgcaga accaaaaatc tttccgagtt tacgtattgc atagcgctta
    18601 ttagtattag attttgccat tacatcctac ttctagtata gcatcttttc tatcaaacgt
    18661 taaacaatat actttatata taaaatagac ttagaatgat atatttacta ttgaactaac
    18721 actttaacta tatcgtaatc aatctcatat ataaaggatt gcagacatct gatctaaata
    18781 catgctaata tatttagata caaacattcc aacttgataa ttttcactca tctttcatca
    18841 ttccttacac aacgatgcag tataaataga ata
//
LOCUS       DAVKAU010000037        18687 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVKAU010000037 DAVKAU010000000
VERSION     DAVKAU010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18687
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.037"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(98..907)
                     /locus_tag="VWX48_001459"
     CDS             complement(98..907)
                     /locus_tag="VWX48_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9172068.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(909..1712)
                     /locus_tag="VWX48_001460"
     CDS             complement(909..1712)
                     /locus_tag="VWX48_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9172069.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1722..3209)
                     /gene="tacF"
                     /locus_tag="VWX48_001461"
     CDS             complement(1722..3209)
                     /gene="tacF"
                     /locus_tag="VWX48_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU9172070.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3545..4252
                     /locus_tag="VWX48_001462"
     CDS             3545..4252
                     /locus_tag="VWX48_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU9172071.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4257..5279
                     /locus_tag="VWX48_001463"
     CDS             4257..5279
                     /locus_tag="VWX48_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9172072.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5296..6165
                     /gene="licA"
                     /locus_tag="VWX48_001464"
     CDS             5296..6165
                     /gene="licA"
                     /locus_tag="VWX48_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU9172073.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            6155..7033
                     /locus_tag="VWX48_001465"
     CDS             6155..7033
                     /locus_tag="VWX48_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU9172074.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7045..7734
                     /locus_tag="VWX48_001466"
     CDS             7045..7734
                     /locus_tag="VWX48_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU9172075.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7820..8668
                     /gene="dprA"
                     /locus_tag="VWX48_001467"
     CDS             7820..8668
                     /gene="dprA"
                     /locus_tag="VWX48_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU9172076.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDIFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9550..10593
                     /locus_tag="VWX48_001468"
     CDS             9550..10593
                     /locus_tag="VWX48_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU9172077.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            10760..12847
                     /gene="topA"
                     /locus_tag="VWX48_001469"
     CDS             10760..12847
                     /gene="topA"
                     /locus_tag="VWX48_001469"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU9172078.1"
                     /translation="MATATKKTKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLTIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13068..13427
                     /locus_tag="VWX48_001470"
     CDS             13068..13427
                     /locus_tag="VWX48_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU9172079.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13520..14152
                     /locus_tag="VWX48_001471"
     CDS             13520..14152
                     /locus_tag="VWX48_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU9172080.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            14196..14852
                     /locus_tag="VWX48_001472"
     CDS             14196..14852
                     /locus_tag="VWX48_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU9172081.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14871..15503
                     /locus_tag="VWX48_001473"
     CDS             14871..15503
                     /locus_tag="VWX48_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU9172082.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEETINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            15531..15965
                     /locus_tag="VWX48_001474"
     CDS             15531..15965
                     /locus_tag="VWX48_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU9172083.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15977..17013
                     /gene="leuB"
                     /locus_tag="VWX48_001475"
                     /pseudo
     CDS             15977..17013
                     /gene="leuB"
                     /locus_tag="VWX48_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            17010..17279
                     /locus_tag="VWX48_001476"
     CDS             17010..17279
                     /locus_tag="VWX48_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU9172084.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYYIWR"
     gene            17283..17642
                     /gene="leuD"
                     /locus_tag="VWX48_001477"
     CDS             17283..17642
                     /gene="leuD"
                     /locus_tag="VWX48_001477"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU9172085.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17804..18372
                     /locus_tag="VWX48_001478"
                     /pseudo
     CDS             17804..18372
                     /locus_tag="VWX48_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
BASE COUNT         5863 a         3206 c         3952 g         5666 t
ORIGIN      
        1 tatgatgcgt tttattgtgg gaatatgtat ttcattttct actaaaatta tgtttttgaa
       61 taacctctat cttagtagtc tgtataatcc ccctcaatca gtttttgcga taagctttaa
      121 tgctatgact ataccactct tgcatttctt ttgatggtgg tgtcatataa tcgccataca
      181 tctgggttaa aaattggtca tattttttgg gaacaggcaa catacggccc tcaaactcag
      241 ttaaaatcag ttctttaaag gtatcaactg ggaagatttc tttcatccct tccttaccga
      301 tcccaactcc tccttcatat tgaggagtgt tggttacagc atttttgact agttgatcaa
      361 ttttcttgta aaagtagcga ggattgacaa atcggagagc gtaccagcta cataatctaa
      421 gaaaatcttt tagtttgcta tcaccgtgaa ctgctcgtga ttttttgata taagctagtt
      481 gacgaagagc cacatactta tagctcttgt cgacaatgct caagtctgta aatcgatcaa
      541 ttgggaagac atcgatgaaa aggctggtat catgacgctt gtacttaaca tggtcttcta
      601 taacagtaga agtgtccaaa atcgatgcga aattatggaa gtaccaagaa gatgtatcgt
      661 aggaaagaac cttgtagcga gggtgatttt cttcttcaat aatcttcagt aaacgctcat
      721 aatcctcacg ataaagggaa atatcaatat catcatccca aggaatcata cctttgtggc
      781 ggatggctcc aagcatggtt ccataactga gaaaataagg aatatcatgt ttcttacaag
      841 tctcatcaat atagtccagc agggctagtt gaatttcttt aatttctttt ttttctaaat
      901 attgcatcct aatcctccaa tttataagcg tgaaattcat gactgtagaa gcgtttttct
      961 tctggtggta gggtcatata atctccataa aattgtgtca aaatagtatc aaatttttca
     1021 ggtgcaggaa ggcttaaatt ctcaaagggt aaatcgattg ttttatcaaa ggtaccactt
     1081 gggaagactt ccttttcctt aaattttgaa ggaataaaag ccatatactg cccattttca
     1141 cgactatatt tttgaatttc tttctcgatt ttatttgcaa aataacgagg agaaaccggt
     1201 cgaaggagca accaaaaggc tgttcgtatc caatctttta aaaggctatc cttatagaca
     1261 atatttttat gtttactgaa agacagcagt ttgaagcttt ccagtttata acaagtatca
     1321 atgaccttag gatcatcaaa gcgatctata gggaaaatat cgataaagat accagactca
     1381 taggtttttg tatttcgagt atcaataatt ttagtcgtac tgtcggttat cttgataaag
     1441 ttgttaaagt agttcttatc agtttctaag gataggagct tatacttgct tttttccttt
     1501 tgaaaaatgt taataaatcg ttggtagtct tctctaggca tggacagatc aatatcgtcg
     1561 tcccaaggga taaagccctc atgtcgaacc gccccaatca gagtaccgta gttaataata
     1621 tagttgatat tgtgcttttt acagagagta tcaatataat ccaaaatttc taattcaatt
     1681 tgtttggcat cttcaatggt tagttgtttc attttaaact cctatgattt tttgaattta
     1741 ttttttaagg ctaggacatg gtttaaaaat tcatagaaaa tgctatcttt tgtgaagaca
     1801 agtagactaa tataagagat agctgataac aagacaatca aaccagtatt aatcaaaaat
     1861 ggcaaattaa tgaccatatc cacaggatac acgaaattaa tcaggaaata aattgctaca
     1921 aaggaaagtg aaaagagaga gtatcgaaca gtatagctaa agatatgtcc caagtggatg
     1981 agttgttttc tatggatgaa aatgatatag aaaacaagta gagaagcctc tgataacata
     2041 gttgtcagta agtagtattc gggagctacg atatggttga aaaagaggag actattcaag
     2101 cccaaattga gtagcccagc aaagactgta tagactgtga tacgtttttc atagccattg
     2161 gtaaagagaa tttgggaacc aagaatggta tctaaggcca ggataatcgt acgaaaagcg
     2221 aagagagagg tcaagatgcc gcctccgata tatttttcac taccgtaaag taggatggca
     2281 tttggtccta aaaccatgag tccaaaactc agtggaatga taaagaagtt aaagattcga
     2341 ctacctctat taaccagaga aacataggct tctttgtctc ctttccccag atagtaactg
     2401 agacgaggca cactcactcc aattgcacct gttacaaccc cagctataac ggtcacaatt
     2461 cgctgagcta tggtatagta actaacgttg acatcaatcc ctgttttaac gaggaagagg
     2521 cgatctaaaa aagtgaagag catattggca ttggcaaaga ctaacatggc tgtcagaggg
     2581 agaaagagtg gtttaaaatc acttaggtga atcttaacaa gtttgatgtc tcttttaatc
     2641 caaaaataac taatcaggta gttaatcagc gtcgataaac tcatcacaag tgtatagaca
     2701 acaatatcgt gttcattttt aacaaataag aaaatagaga ccagcatcag gatacggatg
     2761 aaggcagttt tgtaaaagag aaaactgtaa ttttccagag cttcattgac ccattcgatt
     2821 gaaaaaatct gggcaatgag ttgaatcccc ataacaaggt agaccttttt gacgattgga
     2881 ttatcagtaa agaagagagg ataggctagg atatagacag cagtggtcaa aatcgtacaa
     2941 gcgatgcaca aataaaaaag actagaaaag gttctgttaa gatctttttt gttatccttg
     3001 acattactga tagcccttaa accgtagtta tagacaccat aagttgcaaa gggcaagaaa
     3061 aatgacaaaa tagtgtcgac tgagttgaag taaccatagt cagttcggtc caagacacgc
     3121 gcgacatagg ttccagttag gatgggaaaa ataatattca agacacgaat tcccatgtaa
     3181 gatagagcat ttaattttat acttttcatt caatttacct cgtttttcat tatatcataa
     3241 agttagctaa taagaaatga agggcagtaa gtcaagtaat cactttgaag tttcaaatct
     3301 taagttttaa gttttcttta aggaaagtat attattctga aggactctaa aatttcgcag
     3361 ccatttatta gtaattgcta cagaattcct agtcattact agaaatggac tagtttcttt
     3421 gaataataga actgcataat tctcctattc tagaagggga ggaccagtat ttcttttatg
     3481 ataggactag attgtggtat aatagagaga ataagttttt ttagtaagac aaaggagaaa
     3541 atagatgatt tatgcaggaa ttcttgccgg tggaactggc acacgcatgg ggatcagtaa
     3601 cttgccaaaa caatttttag agctaggtga tcgacctatt ttgattcata caattgaaaa
     3661 atttgtcttg gagccaagta ttgaaaaaat tgtagttggt gttcatggag actgggtttc
     3721 tcatgcagaa gatcttgtag ataaatatct tcctctttat aaggaacgta tcatcattac
     3781 aaagggtggt gctgaccgca atacaagtat taagaaaatc attgaagcca ttgatgctta
     3841 tcgtccgctt actccagagg atatcgttgt tacccacgat tctgttcgtc catttattac
     3901 acttcgcatg attcaggaca atatccaact tgcccaaaat catgacgcag tggacacagt
     3961 ggtagaagcg gttgatacta tcgttgaaag taccaatggt caatttatta cagatattcc
     4021 aaatcgtgct cacctttatc aaggacaaac acctcaaaca ttccgttgca aggacttcat
     4081 ggacctttat ggatctcttt ctgatgaaga gaaggaaatc ttgacagatg catgtaaaat
     4141 ctttgtgatc aaaggaaaag atgtggcctt ggccaaaggt gaatactcaa atctgaagat
     4201 tacaaccgta acagatttga agattgcaaa aagtatgatt gagaaagact agtaaaatga
     4261 ttaatcaaat ttatcaacta actaagccta agtttatcaa tgtcaaatat caggaagagg
     4321 ctattgacca agagaatcat atccttatcc gtcccaacta catggctgtc tgtcatgcgg
     4381 atcagcgtta ctatcaggga aaacgtgatc ccaagatttt gaataaaaag cttccaatgg
     4441 caatgattca cgagtcatgt ggaaccgtca tttctgaccc gaccggaacc tacgaggttg
     4501 gtcaaaaagt tgtcatgatt cccaatcagt ctcctatgca gagtgatgaa gaattctatg
     4561 aaaactacat gacagggacc catttcttgt ctagtggatt tgatggcttt atgagagagt
     4621 ttgtttctct ccctaaagat cgtgtggtgg cttatgatgc tattgaagat acggttgcag
     4681 ccattacaga gtttgtcagt gtgggcatgc acgctatgaa tcgtctattg actcttgctc
     4741 atagcaagcg ggagcggatc gccgttattg gagatgggag tttagctttt gtggttgcca
     4801 atattatcaa ctatactttg ccagaagcag agattgtggt tattggtcgt cattgggaaa
     4861 agttggaact cttctcattt gccaaagaat gctatattac ggataatatt cctgaagatt
     4921 tggcctttga ccatgctttt gaatgttgtg gtggtgatgg tactggacca gctattaatg
     4981 acttgattcg ctacattcgt cctcagggaa cgattctcat gatgggagtt agcgaatata
     5041 aagtcaatct caatactcgc gatgccttag aaaagggctt gattttggtt gggtcatctc
     5101 gttctggtcg cattgatttt gaaaatgcta tccaaatgat ggaagtcaag aaatttgcca
     5161 atcgtcttaa aaatatcctt tatctagaag aacctgtaag agaaattaaa gatattcatc
     5221 gtgtctttgc aaccgattta aacacagcct ttaaaacagt gtttaagtgg gaagtataag
     5281 tactggaggt taattgtgga gaaaatcatt aaagaaaaaa tttcttcctt acttagtcaa
     5341 gaagaggaag tcctcagtgt tgaacaactg ggtggaatga ccaatcaaaa ctatttggcc
     5401 aaaacaacaa ataagcaata cattgttaaa ttctttggta aagggacaga aaagcttatc
     5461 aatcgacaag atgaaaagta caatcttgaa ctactaaagg atttaggctt agatgtaaaa
     5521 aattatcttt ttgatattga agctggtatc aaagtaaatg agtatatcga atctgcgatt
     5581 acgcttgatt caacgtcaat caagaccaag ttcgacaaaa ttactccaat attacaaact
     5641 attcatacgt ctgctaagga attaagagga gaatttgctc cttttgaaga aatcaaaaaa
     5701 tacgaatcct tgattgaaga acaaattcct tatgccaact atgaatctgt tagaaatgca
     5761 gtcttctcct tagagaaaag actggctgac ttaggtgttg acagaaaatc ttgtcatatc
     5821 gatttggtgc ctgaaaactt tatcgaatca cctcaaggac gactttattt gattgactgg
     5881 gaatattcat caatgaatga tccaatgtgg gatttggctg ccctcttttt agagtctgaa
     5941 ttcacttccc aagaggaaga aactttctta tctcactatg agagtgacca aacaccggtt
     6001 tctcatgaaa agattgctat ttataaaatt ttacaagata ctatttggag tctatggact
     6061 gtctataagg aagagcaagg tgaagatttt ggtgactatg gtgtgaatcg ttaccaaaga
     6121 gctattaaag gtttggcttc ttatggaggt tcagatgaaa agtaaaaacg gagttccttt
     6181 tggccttctc tcaggtattt tctggggctt gggtctaacg gttagtgctt atatcttttc
     6241 gatttttaca gatttgtcac cctttgtggt ggctgcaact catgattttt tgagcatctt
     6301 tatcttacta gcttttctct tggtaaaaga agggaaagtt cgcctctcaa ttttcttaaa
     6361 tattcgcaat gtcagtgtta tcataggagc cttgctagca ggccctatcg gtatgcaggc
     6421 caatctttat gcagttaagt atattggaag ttctttagct tcatctgtat cggctattta
     6481 ccctgcgatt tcagttctat tggctttctt ctttttgaag cacaagattt cgaaaaatac
     6541 tgtatttggg attgtcttga ttattggagg gattattgcc cagacctata aggttgaaca
     6601 ggttaattct ttctacattg ggattctttg tgctttggtt tgtgctattg catggggaag
     6661 tgagagtgtt cttagctctt ttgccatgga aagtgaattg agtgaaatcg aagccctctt
     6721 aatccgtcaa gtaacttcgt tcttgtccta tcttgtgatt gtgctcttct ctcatcagtc
     6781 atttgttgca gtagccaatg gacaattgct aggtctcatg attgtctttg tagcctttga
     6841 tatgatttcc tatttggctt attatatcgc tatcaatcgc ttgcaaccag ccaaggctac
     6901 aggcttgaac gtgagctatg tagtatggac tgtcttgttc gcagctcttt tcttgggaac
     6961 atcattagat atgctgacca ttatgacgtc acttgtcgtc attgctggag tttatattat
     7021 tattaaagaa taaaggagat tcgtgtgaaa gccattatct tagcagcggg attgggaact
     7081 cgcttgcgtc ctatgactga aaatacccct aaagccttgg ttcaggttaa tcaaaaacct
     7141 ttgattgaat accaaattga gtttctcaaa gaaaaaggaa tcaatgacat catcatcatc
     7201 gttggttatc ttaaagaaca attcgattat ttaaaagaaa aatacggtgt tcgcctcgtt
     7261 ttcaatgata aatacgctga ctacaataac ttttactctc tctatcttgt aaaagaagaa
     7321 ttggccaaca gctatgttat tgatgctgac aattatctct ttaaaaatat gttccgcaat
     7381 gatttgacac gttcgactta ttttagtgtt tatcgtgaag attgtaccaa cgaatggttc
     7441 ttggtctatg gagatgacta caaggttcaa gacattattg ttgatagcaa ggcaggtcgc
     7501 atccttagtg gtgtatcctt ctgggatgct ccaactgcag aaaagattgt cagctttatc
     7561 gacaaggctt atgcaagtgg tgaatttgtt gatctctact gggacaatat ggttaaggat
     7621 aatatcaaag agctagatgt ctatgttgaa gaattagaag gcaatagcat ttatgagatc
     7681 gatagtgtcc aagactatcg taaattagaa gaaattctta aaaacgaaaa ttaaagattc
     7741 caacatctga caaaatagtc ggatgttttt tgatttttta cgaatagata gatgagtaga
     7801 aaaagaaatg gagttattta tgaaaattac aaactatgaa atctataagt taaaaaaatc
     7861 aggtttgacc aatcaacaga ttttgaaagt gctagaatac ggtgaaaatg ttgatcagga
     7921 gcttttgttg ggtgatattg cagatatctc aggttgccgt aatccagccg tttttatgga
     7981 acgttatttt cagatagacg atgcgcattt gtcgaaagag tttcaaaaat ttccatcttt
     8041 ctctatttta gatgactgtt atccttggga tttgagtgaa atatatgatg cgcctgtact
     8101 tttattttac aagggaaatc ttgacctcct gaaattcccg aaggtagcgg tcgtgggcag
     8161 tcgtgcttgt agcaaacagg gagctaagtc agttgaaaaa gtcattcaag gcttggaaaa
     8221 tgaactggtt attgtcagtg gtctggccaa gggcattgac acagcagctc atatggcagc
     8281 tcttcagaat ggcggaaaaa ccattgcagt gattggaaca ggactggatg tgttttatcc
     8341 taaagccaac aaacgcttgc aagactacat cggcaatgac catctggctc taagtgaata
     8401 tggacctggc gaacaacctc tgaaatttca ttttcctgcc cgtaatcgca tcattgctgg
     8461 actttgtcgt ggtgtgattg tagcagaggc taagatgcgt tcaggtagtc tcattacctg
     8521 tgagcgagca atggaagaag gacgcgatat ctttgctatt cctggtagca ttttagatgg
     8581 actatcagac ggttgccatc atttgattca agaaggagca aaattggtca ccagtgggca
     8641 agatgttctt gcggaatttg aattttaaaa atgacctaag ctagaattct aagaaaaaat
     8701 caattttaag agaaaatgaa cccaacattt ccataataaa acgcatatta gcaagttttt
     8761 aacacttgat aatatgcgtt ttttctaagt ggattagtag agtagaggat tttttcatat
     8821 aatactcttc gaaaatctct tcaaactacg tcagcttcca tctgcaacct caaaacagta
     8881 ttttgagctg acttcgtcag tcttatctac aacctcaaag cagtgctttg agcaacctgt
     8941 ggctagcttc ctagtttgcg ctttgatttt cattgagtat aagggaaagt atagtgaatt
     9001 gaaataagat gtgaacaact ctatcaggaa agtcaaatta atttatagaa atattttagc
     9061 agccaaggtg cactgttata gattcaatac actataattt agtgtaattg agaaaggaga
     9121 aatgattgtg attgatgttg gctaggttat tttcaatgat tcctaccgtc tcaaatcttg
     9181 tcagtaagga aaaataaatt cttcaaaagt agagattaca aggcttgttt aagaaagaat
     9241 tcaaagacct tgacaaataa aaataaaatg gttattataa gaaatggtct aaaatagatg
     9301 atgatacttt tcgaaaatct ttttacgtca gctcagcttt gccttgctgt gttttgagca
     9361 agctacggtt agcttccgag tttgattttc atttactaga aatgaaactg atgagagata
     9421 tcagtagaca tttgagtcag gatattatgg aaaatgataa aaagagctcg tgagattggc
     9481 atatcagact actaaagtat tgagtttgtt aggattttag cgactagtta gctgggaaag
     9541 gaagatattg tgacaaataa taaactgtat tcgttgatag aatttagaaa taaaatatat
     9601 gaagaattag aactttccag aagtgattta gcgattttac tatgtgccat gcttatcgcc
     9661 tctatcggat taaatatgga ttcgactccc gtgattattg gagccatgtt aatctctcct
     9721 ttgatgacac ctattctggg agtggggctc tctctagcta tatttgattt taaattgtta
     9781 agaaaatctt ttaaaatatt agctattcaa attcttgcca gtttaatagc ttcaacactt
     9841 tatttttatc tttctcccat ttcgtatgct agttcggaaa ttgttgctag aacctctccg
     9901 actatttggg atgttctcat tgcttttgta ggagggatag caggtattat tggtgctagg
     9961 aaaaaagaga ccaataatat tgttcctggt gttgctattg caaccgcctt gatgcctcct
    10021 ctttgtacag taggttatgc tattgcttct gctaatctaa aatttatcat aggctcctct
    10081 tacctattcc tcatcaattg tagctttatt gtcattgcga cttatatagg tgttaggttg
    10141 atgatggtta agaaacatta ttttaaagat aatgaagaag actctaaaat gcgtaggatt
    10201 ttgcttctag ttgctgtttt gctgatgatt ccgagtttca tctctgcaac gactttagtg
    10261 agagaaacgt tgaaaaaaga gtcccttaag aaatttatat cagagcagtt tcaggggcat
    10321 aatattttga aaaaaaccta ttctaaaaag actcataccc taaagctaac catttcagga
    10381 aattatttga cagaagaaga actcgatatg atttcaagta agagaggtga ctatggttta
    10441 agtgatgttt ctgttcaagt ttcacaattg tctgattcag aacaacttag taaggaagaa
    10501 ctggtggagt atttcttcca gtatatcaag gataaggaag caaaagaaaa ggaaaaagct
    10561 aataagtttt atacagagtc tgaggagcaa taatttcttg agaatagctg gtttttctcg
    10621 tgagtcttct atgtatatca aaggaagact gaggttttaa gtataaaact tttcttctat
    10681 tatagtagct aagtcttgac agggttcaaa aaatggttta cactttataa agtttattac
    10741 tttgaaaagg tgtgatactg tggctacggc aacaaaaaag acaaaatcaa cagttaaaaa
    10801 aaatctagtc atcgtggagt cgcctgctaa ggccaagacg attgaaaaat atctaggcag
    10861 aaactacaag gttttagcca gtgtcgggca tatccgtgat ttgaagaaat ccagtatgtc
    10921 cgtcgatatt gaaaataatt atgaaccgca atatatcaat atccgaggaa aaggccctct
    10981 tatcaatgac ttgaaaaaag aagctaaaaa agctaataaa gtttttctcg cgagtgaccc
    11041 ggaccgtgaa ggagaagcga tttcttggca tttggcccat attctcaact tggatgaaaa
    11101 tgatgccaac cgtgtggtct tcaatgaaat caccaaggat gcagtcaaaa atgcttttaa
    11161 agaacctcgt aagatcgata tggacttggt cgatgcccaa caagctcgtc ggatcttgga
    11221 tcgcttggta gggtattcga tttcgcctat tttgtggaag aaggtcaaga agggcttgtc
    11281 agcaggtcgc gttcagtcca ttgcccttaa actcatcatt gaccgtgaaa atgaaatcaa
    11341 tgccttccag ccagaagaat actggacagt tgatgctgtc tttaaaaagg gaaccaaaca
    11401 atttcatgct tccttctatg gagtagatgg taaaaagatg aaactgacca gcaatgacga
    11461 agtcaaggaa gtcttgtctc gtctgacgag taaagacttt tcagtagatc aggtggataa
    11521 gaaagagcgc aagcgcaatg ctcctttacc ctataccact tcatctatgc agatggatgc
    11581 tgccaataaa atcaatttcc gtactcgaaa aaccatgatg gttgcccaac agctctatga
    11641 aggaattaat atcggttctg gtgttcaagg tttgattacc tatatgcgta ccgattcgac
    11701 tcgtatcagt cctgtagcgc aaaatgaggc ggcaagcttc attacggatc gttttggtag
    11761 taagtattct aagcacggta gcaaggtcaa aaacgcatca ggtgctcagg atgcccatga
    11821 ggctattcgt ccgtcaagtg tctttaatac accagaaagc atcgctaagt atctggacaa
    11881 ggatcagctc aagctatata cccttatctg gaatcgtttt gtggctagcc agatgacagc
    11941 ggccgttttt gataccatgg ctgttaaatt gtctcaaaaa ggggttcaat ttgctgccaa
    12001 tggtagtcag gttaagtttg atggttatct taccatttat aatgattctg acaagaataa
    12061 gatgttaccg gacatggttg ttggagatgt ggtcaaacag gtcaatagca aaccagagca
    12121 acatttcacc caaccgcctg cccgttattc tgaagcaaca ctgattaaaa ccttagagga
    12181 aaatggggtt ggacgtccat caacctacgc gccaaccatt gaaaccattc agaaacgtta
    12241 ttatgttcgc ctggcagcca aacgttttga accgacagag ttgggagaaa ttgtcaataa
    12301 gctcatcgtt gaatatttcc cagatatcgt aaacgtgacc ttcacagctg aaatggaagg
    12361 taaactggat gatgtcgaag ttggaaaaga gcagtggcga cgggtcattg atgcctttta
    12421 caaaccattc tctaaagaag ttgccaaggc tgaagaagaa atggaaaaaa tccagattaa
    12481 ggatgaacca gctggatttg actgtgaagt gtgtggcagt ccaatggtca ttaaacttgg
    12541 tcgttttggt aaattctacg cttgtagcaa tttcccagat tgccgtcata cccaagcaat
    12601 cgtgaaagag attggtgttg agtgtccaag ctgtcatcag ggacaaatta ttgagcgaaa
    12661 aaccaagcgt aatcgcctat tctatggttg caatcgctat ccagaatgtg aatttacctc
    12721 ttgggacaag cctgttggtc gtgactgtcc aaaatgtggc aacttcctca tggagaaaaa
    12781 agtccgtggt ggtggcaagc aggttgtttg tagcaaaggc gactacgagg aagaaaagat
    12841 taaataagag gaggggcccg aaagtaaatt tcaggctcct tttggttaga acttgacaaa
    12901 atacatcatt ttatgcgaaa ctagaagaag attattttat actcagtgag aatcaaagag
    12961 caaattagaa agctagtcgc aggttgctca aagcactact ttgaggttga agatggaagc
    13021 tgacctggtt tgaagagatt ttcgaagagt attaactagg agaagttatg cgtcttatct
    13081 atctaattat tggtttttta tcgctggcct tggctattgt tggggttgtt ttacccttgt
    13141 tacctacaac acctttcctt ttgttgtcta ttgcttgttt ctccagaagt tccaagcgat
    13201 tcgaagactg gctttatcat accaagctct atcaaacata tgtagctgat tttcgcgaga
    13261 ctaagtctat tacgcgtgaa cgaaagaaaa aaatcatcgt ctctatctac gtcttgatgg
    13321 gaatttctat ttattttgca cctcttttac cagtcaaaat cggtctgggt gctttgacca
    13381 tctttatcac ttattatctt ttcaaggtca ttccagacaa agaatagtta aaacagtagt
    13441 tatttgcctt gataaaattg aaagcatatt cataacaata tgatataata aatttgaagt
    13501 aatattcaag gagaatcaaa tgatttacga attttgtgct gaaaatgtga ctttacttga
    13561 aaaagcgatg caggctggag ctcgtcggat tgaactctgt gataatctag cagttggtgg
    13621 gacaacaccc agctatggag tgactaaggc agcggttgaa ctggcagcta actacgatac
    13681 aaccatcatg accatgattc ggccacgtgg tggtgacttt gtctataatg acctagaaat
    13741 tgctatcatg ctagaagaca tttgtttgac tgctcaggct ggaagtcaag gggttgtatt
    13801 tggagcttta actgctgata aaaagttgga taagcctaat ctggaaaagt taattgctgc
    13861 atcaaaagga atggaaattg tctttcacat ggcctttgat gaactaagtg atgaagatca
    13921 accggaagct attgactggc tcagtcaagc cggtgtcact cgtatcctaa ctcgtgctgg
    13981 tgtgtctggc gactccttag aaaaacgttt tgttcactat cacagaattt tggagtacgc
    14041 taaaggtaaa attgaaattc taccaggtgg ggggattgac cttgacaacc gtcaaacctt
    14101 tattgaccag gtgggggtaa cacaattgca tggtactaag gttgtttttt aaaaaataga
    14161 aaggaactgc tagccttggg tagcagtttt cacttatgtt tgaaattttt aaatcctatc
    14221 aatttaatca agaaaaggct catgattatg gttttataga aaatagcgaa gtctggacat
    14281 atagttgcca gattttgcaa ggtgactttg tcatgactgt gtccatcact gctgataatg
    14341 tgaactttca agtctttgac caagagactg gtgaccttta tcctcacgtt catatggaaa
    14401 gcatgagggg aagttttgtc ggaaatgtcc gtgaggcttg tctggagatt ctttaccaga
    14461 ttcggaaggc ttgttttgat gtgcaagatt ttatctgtca tcagactaag cgtatcatga
    14521 ctcaagttca ggaaaagtat ggaaaccagt tggagtatct gtgggaaaaa tcgcctgata
    14581 cagctgtatt gcgccatgaa ggcaatcaaa agtggtatgc cgtcttgatg aaaatctctt
    14641 ggaataagct ggaaaagggc agagaaggac aagtggaagc agtcaacctc aagcatgacc
    14701 aagtagctaa tttgctttca caaaagggga tttatccagc cttccatatg agcaagcgct
    14761 actggattag tgtgtccctt gatgatactt tatcagatga agaagtactg gaattgatag
    14821 aaaaaagttg gaacttaacc tctaaaaaat gaaatatttt aataattttc atgaactttc
    14881 aattagctaa atattcttta ctgaagaaat tttcagaaaa tataggattt accacaccag
    14941 aggaatgtgg tgccatcttc aaatacctga ttgagaatgt caagacggat cgtcagatca
    15001 tctattcgcc tcactgtcat gatgacctcg gaatggcagt ggcaaatagc cttgctgctg
    15061 tcaagaatgg tgcaggacgt gttgaagaga ctatcaatgg tattagggag cgagctgaaa
    15121 atgctgcttt ggaagaaatt gcagtggctc tcaatattcg ccaagattac taccaagtag
    15181 aaaccagtat tgtcctaaat gagaccatca atacgtcaga aatggtttct cgcttctctg
    15241 gtattccagt tcctaaaaac aaagccgtcg ttggtggcaa taccttctcc cacgaatctg
    15301 gtattcacca agatggagtc cttaaaaatc ctctcactta tgagatcatc acacctgaat
    15361 tggttggtgt taagattccg cttggaaaat tatctggtcg ccatgctttt gttgagaaac
    15421 tgagagaatt ggccctagat tttacagaag aggatatcaa accactcttt gctaagttca
    15481 aggcactggc cgataagaag taagaaatca cagatgcaga tactcgagct ttggtagctg
    15541 gaaccatggt tgaaaatcca gaaggcttcc actttgatga tttacaactt caaactcatg
    15601 cagataatga cattgaagcg ctcgttagcc tagccaatat ggatggtgag aaagtcgaat
    15661 ttaatgcgac agggcaaggt tccgttgaag caatctttaa cgctatcgat aagttcttta
    15721 accaatctgt tcgtttggtg tcctacacta tcaatgcggt aacagatgga atcgatgccc
    15781 aggatcgggt tttggtcact gttgaaaaca gagatacaga aaccatcttt aatgcagcag
    15841 ggcttgattt tgatgtgttg aaggcttctg ctattgccta tataaacgct aatacctttg
    15901 ttcaaaaaga gaatgcaggt gagatgggac gcagtgtttc ttaccacgat atgcctagtg
    15961 tgtaaaggag aaggctatgg caaagaaaat agtagctcta gtaggagacg gaattggccc
    16021 agaaatcatg gaggctggtt tagaagttct ggaggctcta gctgaaaaaa caggttttga
    16081 ctatgagatt gacagacgac cgttcggagg tgcagatatt gatgcagcag gacctccctt
    16141 acctgatgaa acccttaagg caagtaggga agcagatgct atcctactag tagctatcgg
    16201 tagtcctcag tatgatggag tagcggttcg ccctgaacaa ggcctgatgg ctctccgtaa
    16261 gaactcaatc tttacgctaa tattcgtcct gtaaaaatct ttgacagtct caagtatttg
    16321 tcaccactca aaccggaacg aatttctggt gtagactttg tcgtggtgcg tgaattgaca
    16381 ggcgagattt actttggaga tcatattctt gaagagcgca aagcgcgtga tatcaacgac
    16441 tatagctatg aggaagtgga gcggattatt cgcaaagcct ttgaaattgc aagaaatcgc
    16501 agaaaaatcg ttactagtat cgataagcaa aatgttctag cgacctcaaa actctggcgg
    16561 aaagtagctg aggaagtcgc acaggatttc tcagatgtaa ccttggaaca ccagctggta
    16621 gactcagctg ctatgcttat gattaccaat cctgctaagt ttgatgttat tgtaacggag
    16681 aatctttttg gagatatttt atctgatgaa tcaagcgtct tatctggtac acttggggtt
    16741 atgccatcag ccagtcattc tgaaaatgga ccaagtctct atgaacctat tcacggttca
    16801 gcacctgata ttgcaggtca aggaattgcc aatcctattt ccatgatttt atcagttgtc
    16861 atgatgttga gagatagttt cggacgttat gaggatacag agcgtatcaa acgtgctgtt
    16921 gagacaagtc tggcggcagg aattttaacg agagatatag gaggtcaggc ttcaacaaag
    16981 gaaatgatgg aagctattat tgcaaggtta tgaagttaga cgaaaaaatt actctagtcc
    17041 ttttgatttg gaatgtcatc attttcttga tttatggcat tgacaaattc aaggcaagaa
    17101 gaagagcttg gcgcatccca gagaaaatct tactcatttt agcccttact tgtggtggtt
    17161 ttggggcctg gttagctgga atcacttttc accacaagac tcgaaaatgg tactttaaaa
    17221 cagtttggtt tcttgggatg gtgaccacac tagtagcctt atattatatt tggaggtaat
    17281 ggatggcagg gtcttcgagg gaacacgctg cttgggctct agcggactat ggttttaagg
    17341 tcgtgattgc aggatctttc ggtgacattc attacaataa tgaactcaat aatggcatgt
    17401 tgccaatcgt tcagcctaga gaggttagag agaaactagc ccagttaaaa ccaaccgacc
    17461 aggtaactgt ggacttggaa caacaaaaaa tcatctcacc agttgaagaa ttcaccttcg
    17521 agatagatag caagtggaaa cataaactcc taaatagttt ggatgatatc ggtattacct
    17581 tgcagtatga agagttgatt gctgcttatg aaaaacaacg accagcctac tggcaggatt
    17641 agaaaaaata gaaaaggaaa tatagtaaac tgaaataaga tgtaaacaaa tgaattggag
    17701 cttaacatca atttccagca attttttaga aactacagtg gactattctg gattcaacac
    17761 attataaaat tatgacaaaa cacattcaca agaaggctac gacattttaa aaggtgaggg
    17821 cggatgtatc gtttgcccta ctaaagttgg ttacattatc atgaccagca acaaggcagg
    17881 acttgagcgt aagttcgcag ccaaagaacg taagcgtaac aaaccaggtg ttgttctctg
    17941 cggtagcatg gatgaacttt gcgctttagc gcaactcaac ccagaaattg aagcattcta
    18001 ctaaaaacat tgggatgaag atattcttct tggttgtatc cttccttgga aaccagaagc
    18061 ctttgaaaaa ctcaaagcat acggggatgg ccgtgaagaa cttatgactg atgtacgtgg
    18121 tactagctgt tttgttatca agtttggaaa agcaggtgaa caattggctg ccaagctttg
    18181 ggaagaaggt aaaatggtct acgcctcatc tgcttcaatg acaaaacgac tgaaactcgc
    18241 tatgagcaag gtgtaatggt gtctatggtc gataaggacg gcaaactcat cccagaacaa
    18301 ggaggagcac gttcaacctc accagcacca gttgtgatcc gtaaagggct tgacattgat
    18361 atagtaaaat gaagtaagat cagcacaaag taatcaggac agtcaaatcg atttctaaca
    18421 atgttttaga agtagaggtg tactattcta gtttcaatct actataaaat catgatgcac
    18481 ctgtcagata cttttaactc atgggactac cgtcagggtg agtattatta agataaaaaa
    18541 agaagtctag tgttatgaga tattaaagct cctaacactg ggctttttgt ttagaatttc
    18601 ttttattttt ctataggata tgatatgcta gatgcagaat atattaatag aatgtagttt
    18661 ctgcaaagta aaatatctta ctttgaa
//
LOCUS       DAVKAU010000038        18376 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVKAU010000038 DAVKAU010000000
VERSION     DAVKAU010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18376
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.038"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1173..2432
                     /locus_tag="VWX48_001479"
     CDS             1173..2432
                     /locus_tag="VWX48_001479"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9172086.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGTSVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2448..2999
                     /locus_tag="VWX48_001480"
     CDS             2448..2999
                     /locus_tag="VWX48_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9172087.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            2992..4269
                     /locus_tag="VWX48_001481"
     CDS             2992..4269
                     /locus_tag="VWX48_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9172088.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            4285..5145
                     /locus_tag="VWX48_001482"
     CDS             4285..5145
                     /locus_tag="VWX48_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU9172089.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5526..6329
                     /locus_tag="VWX48_001483"
                     /pseudo
     CDS             5526..6329
                     /locus_tag="VWX48_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004897104.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            6521..8812
                     /gene="pcrA"
                     /locus_tag="VWX48_001484"
     CDS             6521..8812
                     /gene="pcrA"
                     /locus_tag="VWX48_001484"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU9172090.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            8855..9535
                     /gene="radC"
                     /locus_tag="VWX48_001485"
     CDS             8855..9535
                     /gene="radC"
                     /locus_tag="VWX48_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU9172091.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(9532..10221)
                     /locus_tag="VWX48_001486"
     CDS             complement(9532..10221)
                     /locus_tag="VWX48_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9172092.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(10239..10880)
                     /locus_tag="VWX48_001487"
     CDS             complement(10239..10880)
                     /locus_tag="VWX48_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU9172093.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(10963..11178)
                     /locus_tag="VWX48_001488"
     CDS             complement(10963..11178)
                     /locus_tag="VWX48_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9172094.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(11186..11533)
                     /locus_tag="VWX48_001489"
     CDS             complement(11186..11533)
                     /locus_tag="VWX48_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU9172095.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(11538..12653)
                     /locus_tag="VWX48_001490"
     CDS             complement(11538..12653)
                     /locus_tag="VWX48_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9172096.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(12663..13622)
                     /locus_tag="VWX48_001491"
     CDS             complement(12663..13622)
                     /locus_tag="VWX48_001491"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9172097.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(13735..14304)
                     /locus_tag="VWX48_001492"
     CDS             complement(13735..14304)
                     /locus_tag="VWX48_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU9172098.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            14432..15103
                     /locus_tag="VWX48_001493"
     CDS             14432..15103
                     /locus_tag="VWX48_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU9172099.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            15087..15905
                     /locus_tag="VWX48_001494"
     CDS             15087..15905
                     /locus_tag="VWX48_001494"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU9172100.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            15902..16798
                     /locus_tag="VWX48_001495"
     CDS             15902..16798
                     /locus_tag="VWX48_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9172101.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            16842..17816
                     /gene="pta"
                     /locus_tag="VWX48_001496"
     CDS             16842..17816
                     /gene="pta"
                     /locus_tag="VWX48_001496"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU9172102.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(18132..>18376)
                     /locus_tag="VWX48_001497"
     CDS             complement(18132..>18376)
                     /locus_tag="VWX48_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9172103.1"
                     /translation="ALAFPPLFQTLFKTFLKDKEKIVNALQLPYSNAKLEATNNLIKL
                     IKHNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5470 a         3344 c         4020 g         5542 t
ORIGIN      
        1 gttacccact acaaatatta tagagccaaa aatcccgtgc ctcatcaaac acgggatttt
       61 gtggtacgac gggcatgtat agcgaactga atctggaata gcacagcata tcttctaaaa
      121 tatagtaaaa tgaaatgaga acagaacaaa tcgatcagga cagtaaaatc gatttctaac
      181 aatgttttag aagcagaggt gtactagtct agtttcaatc aactatattg ttataaattg
      241 atttgaattt caaaattaaa ttgtttgatt cttatttcaa tttgttatag tatatctgat
      301 gtcaaagttc tcggcgagtc aaatagcgat tcccaagcct gactatcgtg aggtagtgga
      361 ttaaaacggt ctggggatag accgttttaa gtctgacgct ggaaataaga atcgtcagag
      421 gaagggatag cgaaatcgtg gctttacgaa caggaacgtg atagtaaggc gtatatagcg
      481 gataaggggg tctcaaactc taaagtccaa aaaggtagtc gtaacctata tgcgtaaatc
      541 acgagagtaa ttgaattcgt actaagattt tctattttca ctgtaacctt ttaacgtcct
      601 tatatcttgt atacacgagg aaagatgtac gacttatccc gtgaggtcta tcactataaa
      661 gagaaaacga cagatagaag tgatcctgag tcacggttat ctttaaaata gattgtctga
      721 taggacggta tgtataaaac gcttctgtga actgagagaa ggggagaagt tcttgctaaa
      781 atttagttga acagccgtat tccgatactt agataagaga tctagtctta gatcctactc
      841 agttttaggg gataaaaaag gggcaatagc gattcgagaa agattatact cttcgaaaat
      901 ctcttcaaat cacgtcaata tcgccttgcc gtatgtgtag gatactgact acgtcagttc
      961 catctacaac ctcaaaacag tgttttgagc aacctgcggc tagtttccta gtttgatctt
     1021 tgattttcat tgagtattag taattcagtt actaactcgt caactctgat ttatccaata
     1081 aaattgaaaa ggatggaaaa aaggataaat ttatgatata ctttattttg aagaccttat
     1141 tagaaatctt gaaagagtat tgaaaactta gaatgagaaa aattgttatc aatggtggat
     1201 taccactgca aggtgaaatc actattagtg gtgctaaaaa tagtgtcgtt gccttaattc
     1261 cagctattat cttggctgat gatgtggtga ctttggattg cgttccagat atttcggatg
     1321 tagccagtct tgtcgaaatc atggaattga tgggagctac tgttaagcgt tatgacgatg
     1381 tattggagat tgacccaaga ggtgttcaaa atattccaat gccttatggt aaaattaaca
     1441 gtcttcgtgc atcttactat ttttatggga gcctcttagg ccgttttggt gaagcgacag
     1501 ttggtctacc gggaggatgt gatcttggtc ctcgtccgat tgacttacac cttaaggcgt
     1561 ttgaagctat gggtgccact gctagctacg agggagataa catgaagtta tctgctaaag
     1621 atacaggact tcatggtgca agtatttaca tggatacggt tagtgtggga gcaacgatta
     1681 atacgatgat tgctgcggtt aaagcaaatg gtcgtactat tattgaaaat gcagcccgtg
     1741 aacctgagat tattgatgta gctactctct tgaataatat gggtgcccat atccgtgggg
     1801 caggaactaa tatcatcatt attgatggtg ttgaaagatt acatgggaca cgtcatcagg
     1861 tgattccaga ccgcattgaa gctggaacat atatatcttt agctgctgca gttggtaaag
     1921 gaattcgtat aaataatgtt ctttacgaac acctggaagg gtttattgct aagttggaag
     1981 aaatgggagt gagaatgact gtatctgagg acagcatttt tgtcgaggaa cagtctaatt
     2041 tgaaagcaat caatattaag acagctcctt acccaggctt tgcaactgat ttgcaacaac
     2101 cgcttacccc tcttttacta agagcgaatg gtcgtggtac aattgtcgat acgatttacg
     2161 aaaaacgtgt aaatcatgtt tttgaactag caaagatgga tgcggatatt tcgacaacaa
     2221 atggtcatat tttgtacacg ggtggacgtg atttacgtgg gaccagtgtt aaagcgaccg
     2281 acttaagagc tggggctgca ctagtcattg ctgggcttat ggctgaaggt aaaactgaaa
     2341 ttaccaatat cgagtttatc ttacgtggtt attctgatat tatcgaaaaa ttacgtaatt
     2401 taggagcgga tattagactt gttgaggatt aaaccgtaga ggtgtttatg aatatttgga
     2461 ccaaattagc aatgttttct ttttttgaaa cggatcgctt gtatttgcgt cctttctttt
     2521 ttagtgatag tcaggacttc cgcgagatag cttcaaatcc agaaaatctt caatttattt
     2581 tcccaacgca ggcaagtctg gaagaaagtc aatatgcact ggccaattac tttatgaagt
     2641 cccctttggg agtgtgggca atttgtgacc agaaaaatca acaaatgatt ggttctatta
     2701 aatttgagaa gctagatgaa atcaaaaaag aagctgagct tggctatttt ttgagaaaag
     2761 atgcttggtc gcaaggattt atgacagagg ttgttagaaa aatttgtcag ctttcttttg
     2821 aggaatttgg cttaaaacaa ttatctatca ttacccacct tgaaaatgaa gctagccaaa
     2881 gagttgctct taagtctgga tttagtttgt tccgtcagtt taagggaagt gatcgttaca
     2941 caagaaaaat gcgggattat cttgaatttc ggtatgtaaa aggagagttc aatgagtaag
     3001 catcaggaaa ttctaagcta tttggaggaa ttaccagtag gtaaaagggt cagtgttcgt
     3061 agcatttcga atcatctagg agttagtgat ggaacagcct atcgggctat taaagaagct
     3121 gaaaaccgtg gaattgtgga gacccgtcct agaagtggaa caattcgtgt taaatcccag
     3181 aaagttgcta tagagagatt aacgtttgct gaaattgcag aagtgacttc ttctgaggtt
     3241 ctggctgggc aagaaggttt agagagagaa tttagtaagt tttcaattgg tgccatgact
     3301 gaacaaaata tcttgtctta ccttcatgat ggggggctct tgattgtcgg agaccgaacc
     3361 cgtattcagt tgctagcctt ggaaaatgaa aatgcagttc tggttacagg gggatttcag
     3421 gttcatgatg atgtgcttaa actggccaat caaaaaggga ttcctgttct aagaagtaag
     3481 catgatacct ttaccgtcgc gaccatgatc aataaagcct tgtcaaatgt ccaaatcaag
     3541 actgatattc tgacagttga gaaactttat cgccctagtc atgagtatgg ttttctgaga
     3601 gagacagata cagttaaaga ttatttggac ttggttcgta agaatcgtag cagccgtttc
     3661 cctgttatca atcaacatca ggtcgttgtt ggcgttgtaa ccatgagaga cgctggtgat
     3721 aaatcaccaa gcacgacaat tgataaggtt atgtctcgta gtctattttt ggttggatta
     3781 tcgacaaata ttgccaatgt gagtcaacgg atgatcgcag aagactttga aatggtacca
     3841 gttgttcgaa gcaatcaaac tttgcttggc gttgtgacgc gacgagatgt catggagaag
     3901 atgagccgtt cccaagtttc ggctctacca actttttctg agcagattgg acaaaagctc
     3961 tcttatcacc atgatgaagt agtcattaca gtggaaccct ttatgctaga aaaaaatgga
     4021 gttttggcta atggtgtatt ggcagaaatt ctgacccaca tgacccaaga tttagttgtt
     4081 aatagtggtc gcaatctcat tatcgagcag atgctgatct actttttgca ggctgttcag
     4141 atagatgata tattgcgcat tcaggcacgg attattcatc atacgagacg gtcagctata
     4201 attgattacg atatttatca tggtcaccag attgtttcaa aagcaaatgt gactgttaaa
     4261 attaattaga aactaggaga aaagatgata acattaaaat cagctcgtga aatcgaagct
     4321 atggacaagg ctggtgattt tctagcaagt attcatatag gcttacgtga tttgattaag
     4381 ccaggcgtag atatgtggga agttgaagaa tatgtccgcc gtcgttgtaa agaagaaaat
     4441 ttccttccac ttcagattgg ggttgacggt gccatgatgg actatcctta tgctacctgt
     4501 tgctctctta acgatgaagt ggctcacgct ttccctcgtc attatatctt gaaagatggt
     4561 gatttgctca aagttgatat ggttttggga ggtcccattg ctaaatctga cctaaatgtc
     4621 tcaaaattaa acttcaacaa tgttgaacaa atgaaaaaat acactcagag ctattctggt
     4681 ggtttagcag actcatgttg ggcttatgct gttggtacac cgtccgaaga agtcaaaaac
     4741 ttgatggatg taaccaaaga agctatgtac aagggtattg agcaagctgt tgttggaaat
     4801 cgtatcggtg atatcggtgc ggctattcaa gaatacgctg aaagtcgtgg ttacggtgta
     4861 gtgcgtgatt tggttggtca tggtgttggc ccaactatgc acgaagaacc aatggttcct
     4921 aactatggta ttgcaggtcg tggactccgt cttcgtgaag gaatggtctt aaccattgaa
     4981 ccaatgatca atacaggcga ttgggaaatt gatacagata tgaaaactgg ttgggcgcat
     5041 aagaccattg acggtggatt gtcatgtcag tatgaacacc aatttgtcat tacgaaagat
     5101 ggacctgtta tcttgactag ccaaggtgaa gaaggaactt attaataaaa agtgaaaaga
     5161 ctactggaag tttattttga taaaaaatcc agtagatctt ttcataataa aacgcattgt
     5221 atcaagtgtt aggggctgat atcatgcgtt tttctgcttt taagattttt tccaactctg
     5281 tttgtaagcg catcataaca aagggtctag gattcagggc tctcctccta tatactatta
     5341 gtaaagtaaa actaagagag gatattttag tgtcgcagtc tattgttcct gtagagattc
     5401 cacaatattg tcgttttgat tctaaaaaga gaaatggaat tctgtttaac gttcgtattg
     5461 ccaatcttaa atttaccttt tttagattag acttcctgcg aaacaaaata tggtatagta
     5521 gttccatgaa tgatgaagca agtaaacaac taactgatgc acgatttaag cgtcttgttg
     5581 gtgttcagcg caccactttt gaagagatgt tagctgtgtt aaaaacagct tatcaactta
     5641 aacacgcaaa aggtggacga aaacctaaat taagcctaga agaccttctt atggccactc
     5701 ttcaatatgt gcgagaatac cgcacttatg aagaaattgc gactgatttt ggtattcacg
     5761 aaagcaactt aatccgtcgg agccaatggg ttgaagtaac tcttgttcaa agtggtgtta
     5821 cgatttcaag aactcctctc agttctgagg acacggtaat gattgatgcg acggaagtaa
     5881 aaatcaatcg ccctaaaaaa acaattagcg aatcattctg gtaaaaagaa atttcacgct
     5941 atgaaggctc aagcgattgt cacaagtcaa gggagattgt ttctttggat atcactgtga
     6001 actattgtca tgatatgaag ttgttcaaaa tgagtcgcag aaatatcgga caagctggta
     6061 aaatcttggc tgacagtggt tatcaagggc tcatgaagat atatcctcaa gcacaaactc
     6121 cacgtaaatc cagcaaactc aagccgctaa cagctgaaga taaagcctgt aaccatgcgc
     6181 tatccaagga gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt
     6241 tttcaacaac ctatcgaaat catcgtaaac gcttcggatt acgaatgaat ttgattgctg
     6301 gcattatcaa tcatgaacta ggattctagt tttgcaggaa gtctattgag gtattgagct
     6361 agtttatgaa aaaattgggt gaaaaagtcg agtgttttag aaacccacag tgtagtattc
     6421 tagtttcaat ccactatatt ttgctactcc ccgtaaagtt tctattttcc ctgatttctg
     6481 atataataga aatattgact tcaagagtaa ggaagagaag atgaacgcat tattaaatgg
     6541 aatgaatgac cgtcaggctg aggcggtgca aacgacagaa ggtcccttgc taatcatggc
     6601 aggggctggt tctggaaaga ctcgtgtttt aacccaccgt atcgcttatt tgattgatga
     6661 aaagctggtc aatccttgga atatcttggc cattaccttt accaacaagg ctgcgcgtga
     6721 gatgaaagag cgtgcttata gcctcaatcc agcgactcag gactgtctga ttgcgacctt
     6781 ccactccatg tgtgtgcgta ttttgcgtcg cgatgcggac catattggct acaatcgtaa
     6841 ttttacaatt gtggatcctg gtgaacagcg aacgctcatg aaacgtattc tcaaacagtt
     6901 gaacttggac cctaaaaaat ggaatgaacg aactattttg gggaccattt ccaatgctaa
     6961 gaatgatttg attgatgatg ttgcttatgc tgcccaagct ggcgatatgt atacgcaaat
     7021 tgtggcccag tgttatacag cctatcaaaa agaacttcgt cagtctgaat ccgttgactt
     7081 tgatgatttg attatgctga ccttgcgtct ctttgatcaa aatcctgatg ttttgaccta
     7141 ctaccagcaa aaattccaat acatccacgt tgatgagtac caagatacca accacgctca
     7201 gtaccaattg gtcaaactct tggcttcccg ttttaaaaat atctgtgtgg ttggggatgc
     7261 ggaccagtct atctacggtt ggcgtggtgc tgatatgcag aatatcttgg actttgaaaa
     7321 ggattacccc aaagccaagg ttgttttgtt ggaggaaaat taccgctcaa ccaaaaccat
     7381 tctccaagcg gccaacgagg ttattaaaaa taataaaaat cgccgtccta aaaatctctg
     7441 gactcaaaac gctgatgggg agcaaatcgt ttactatcgt gccgatgatg agctggatga
     7501 ggctgtattt gtagccagaa ccatcgatga acttagtcgc agtcaaaact tccttcataa
     7561 ggattttgca gttctctatc ggactaatgc ccagtcccgt acaattgagg aagccctgct
     7621 caagtctaac attccttata ccatggttgg cggaaccaaa ttctacagcc gtaaggaaat
     7681 tcgcgatatt attgcttatc tcaaccttat tgctaatttg agtgacaata ttagttttga
     7741 gcgtattatc aacgagccta aacgtggaat tggtctaggt acagttgaga aaatccgtga
     7801 ttttgcaaat ttgcaaaata tgtctatgct ggatgcttct gctaatatta tgttgtctgg
     7861 tatcaagggt aaggcagccc aatctatctg ggattttgcc aatatgatgc ttgatttgcg
     7921 ggagcagcta gaccacttaa gcattacaga gttggttgag tccgtcctag aaaaaacagg
     7981 ttatgtcgat attcttaacg cccaagcgac tctagaaagc aaggcacggg ttgaaaatat
     8041 cgaagagttt ctttctgtta cgaagaactt tgatgacacc acggatgtga cagaagagga
     8101 aactggtctg gacaaactga gtcgtttctt aaatgacttg gctttgattg ccgacacaga
     8161 ttcaggtagt caggagacat cagaagtgac cttgatgacc ctgcatgctg ccaaaggtct
     8221 cgaatttcca gttgtctttt tgattgggat ggaagaaaat gtctttccac ttagtcgtgc
     8281 gactgaagat tcagatgaat tagaagaaga gcgccgtcta gcctatgtag gtatcacgcg
     8341 tgcagagaaa attctctatc tgaccaatgc caactcacgc ttgctttttg gtcgtaccaa
     8401 ttataaccgt ccgactcgtt ttattaacga aatcagttca gacttgcttg agtatcaagg
     8461 tctggctcgt cctgcaaata caagctttaa ggcatcatat agcagtggta gtatttcctt
     8521 tggtcaaggt atgagtttgg ctcaggctct tcaagaccgt aaacgcggtg ctgccccaaa
     8581 atcaatccag tcaagcggtc ttccatttgg tcaatttaca gctggcgcaa aaccagcatc
     8641 tagcgaggca aattggtcca ttggtgatat tgctctccac aagaaatggg gagagggaac
     8701 cgttctggaa gtttcaggta gcggtgctag gcaggaattg aaaatcaatt tcccagaagt
     8761 aggtttgaaa aaacttttag ccagtgtggc tccaattgag aaaaaaatct aattttccat
     8821 ccttctcacg aataataaag tgaggaggat ttttatgtac agtatttcat tccaagaaga
     8881 ttcactatta ccaagagaaa ggctggccaa ggaaggagtt gaagcgctta gtaaccaaga
     8941 gttgctagct attttactca ggacaggaac acgtcaagct agcgtttttg aaattgccca
     9001 aaaagtcttg aacaatcttt caagcctaac ggatttgaaa aaaatgaccc tgcaggaatt
     9061 gcagagtttg tctggtattg ggcgtgttaa ggccatagaa ttacaagcta tgattgaact
     9121 ggggcatcgt attcacaaac acgagactct tgaaatggaa agtattctca gcagtcaaaa
     9181 gttggccaag aagatgcagc aggaattagg ggataaaaaa caagagcacc tggtggcact
     9241 ctatctcaat actcaaaatc aaatcatcca tcagcagacc atttttatcg ggtctgtaac
     9301 tcgtagtatc gctgaaccgc gagagattct tcactatgca atcaagcata tggcgacttc
     9361 tcttatcttg gtccacaatc atccttcagg agcggtagcg cctagccaaa atgatgatca
     9421 tgtcactaaa cttgttaaag aagcctgcga attgatgggg attgttctct tggaccattt
     9481 gattgtctct cattctaatt actttagtta tcgtgaaaag acagatttaa tctaaagttc
     9541 attaacgaca tagtcaaaga gttttttatc tttgggacga ttttcaaaaa gaagttctgg
     9601 atgccattgg acaccgagaa aggcgacatc atccgtactc atgacagcct caatgatacc
     9661 atctttagga tcatgagcca caacttttaa atttggtgct aagtccttga tgctctggtg
     9721 gtggaaggag ttgatatgag agatttctcc atagatttct tggagaacgg tatctggttc
     9781 tgttaccaag cgttgagttg tgtactcaac agaagaatcc tgccaatggt cttcgatatc
     9841 ttggtacaaa gttccaccca tggcaacgtt aaagagttgg gtaccacggc agacagagaa
     9901 aatgggcttt ttctgtttaa tagcttcctt gatgagggcc agttcgaaga tatctctttg
     9961 aaggtgatag tcatcactat caatggtttt gggttcgcca taaaattttg gatcgacatt
    10021 ttgcccacct gtcaagatga gcttgtcaat caaactgata tagtggcagg ccatttcttg
    10081 atcaccaatc ggtaggatga tgggaatccc tccagcatct ttaacgcctt caacaaagcc
    10141 ttttgctgcg tagctcatca tgatgtcatc atctggatga gttttttcgt ttcctgtaat
    10201 cccaataact ggttttttca taaaatgatt ttcgctttct aatcctcttt tcgcatgaag
    10261 tagaggaggg tttggagttc acttgtcaaa tcgacatact gaacgaccac gtcttttggt
    10321 aaatgcagat ggactggtga aaaactgaga attcctttca caccagcatc aaccaagaga
    10381 ttagcaacct cttgtgactt gacgctggga acagttagga tagcagtctt cacatcagca
    10441 tccttgattt tatccttgat ctgagaaatc ccgtaaatgg gaatcccgtc aggagtttgg
    10501 gtaccgactt caggatggtc gtctaggtca aaggccatga taatcttcat cttgttacgt
    10561 tcgtggaagc ggtagtggag aagggcatgg cccatatttc caataccaac cagcatgaca
    10621 ttggtaatag agttgtcatt gagcaaatcg gcaaaaaatg tcattagttt tttgacatca
    10681 tagccaaaac cacgacgacc aagttcacca aaataggaaa aatcacgacg tacggtcgct
    10741 gaatcaatac cgatagcctc tgcaatttgc ttagagttgg cacgttcaat cttttctgca
    10801 tgaaatctct taaaaattcg atagtagaga gagagtcttt ttgctgtagc ttttggaata
    10861 gcaaactgtt tatctttcac aaaatcacaa cctttctatt cttctatttt atagaaacat
    10921 tgtgaaaaaa tcaacaaaaa taagaaaaaa ctaagaaaaa tcttagtttt gatgtaaaaa
    10981 atctgcatga gatagaaaac ggtagaggtc tccgaccagc ccctgataaa cttttttgcc
    11041 cctaaaagtc agagaagtca cataaagtgt atctggtaag gttacacatc ctgacaaagt
    11101 caacatgaga gcctcatgat cctcatactt gagagtacgc tctacatgat agcagtcctt
    11161 ataggtcagt tcaaacattt tggctctatc tttccgattt tgtaaagaca ccacgttcta
    11221 ccaagctatc catgaggaag tagaattttt cctgatgaat atggtggtct tctgatttga
    11281 aaatatcaac tagacgaagg ccaaacttgt cagtgatatt gattttagcc cctgtaagtt
    11341 ccttgttaat gatgattttg agttggaagc cttcaccgct gtttggcact ttttccaaaa
    11401 ggcgagtcag ttcatagtta ccaaccttag tttcaaaaaa ggtgttatct ttgagggtga
    11461 attttttaac agaagggcta agagtgtaat cgtaacgaca attttttaac tgaatgattt
    11521 tttcaaatgc catatggcta acctccgata atttctttta aggtttttgc gagggtttgt
    11581 aggtcttcaa cggtattttg tggcgacaaa ctgatgcgaa gggattcctt caagcgttct
    11641 gaatttgcgc catacatggc tttaagaaca tggctggatt ggacaacgcc tgcagtacag
    11701 gctgagccag tagagattga aattccagct aaatctagcc gaaggagtaa gaggtcattt
    11761 ttctgaccag gaaatccaat attgagaaca taagggagat gatgttttcc tctattcaag
    11821 taatactgaa tgccctccag ctctgccaga aaggcagttt ctagattttg tacatgttga
    11881 aaatgttctt cttgtttttc taggtcttct tttagggctg caaccatgcc tacgatggca
    11941 ggcagatttt cagttcctgc acgttttttc tgttcctgat ctccgccatg tagataggaa
    12001 tcaaagtcca tgctagatgc gtagagaaaa ccgattccct taggaccatg gaatttgtgg
    12061 gcagaagcag tgagaaaatc aatgcccaat tcttctgaat gaattgggat tttaccaata
    12121 gcctgaactg catcaacatg ataggcagca gggtgttgct tgagtatttg gccaatttca
    12181 gcgatgggaa gtaggtttcc tgtctcatta ttggcaaaca tagtagaaac caaaatcgta
    12241 tcgtcacgta aagccttttg aatttgctgg gctgtgattt cttgattttc tggctggata
    12301 atggttgctt caaacccaaa gtgttgaacc aagtaatcaa ttgtttcaag gacagcatgg
    12361 tgctcgatgg cagttgtgat gatatgtttt ccttgttctt ggtgacgaag acagtagcca
    12421 atgatggtag tattattgcc ttcagtccca ccagaagtga aaaagatatg ttgaggtttt
    12481 gtccttagta actgggctag ttcctgacgg gcttctcgca agagtttgcc agcttgacga
    12541 ccatgaccat gaatactaga aggatttccg tgggtttctt gcataacctt ggtcatagct
    12601 gaaatagcaa ctgctgacat aggagtcgtt gcagcattgt ccaaataaat caaagaatca
    12661 ccttatttct ttttattgta ggcaaagagt gggctgactg gttttctttc gtgaatacgg
    12721 acgatagcat caccaattaa ctcactagca gtgatgtagc atacattttt aggagttttt
    12781 tcttttgttg ctactgaatc agtcacaaga atttctttaa tattagtatt gtcaagaagc
    12841 tcagcagctc cctcgacgaa gagaccgtgg ctagaaacag cataaatttc tgtagctcct
    12901 tcacgttcaa cgattttaga agcttcagag aaggtacgtc ctgtatttaa aatatcatca
    12961 atcaagatag ctttcttacc ttcaacatca ccaataatat aaccttcgtt acgagttgca
    13021 tcgtcttgag ggtagtcgat aatggcgata ggagcatcaa gatattcagc caggctacgc
    13081 gcacgtttga cacctgaatt tttagggcta acgacaacaa catctgaacc aagcaatcct
    13141 ttatcgcagt aatgttttgc gaatagggga acagtgaaaa gattatccac tggaatatca
    13201 aaaaaacctt gaacctgaac ggcatgtaaa tcaagagtca ggatacgatc aactccagcc
    13261 ttaaccagca tattggcaac tagttttgct gtaagtggct cacgaggaca agcaatgcgg
    13321 tcttgacgtg catagccaaa atatggaagg acaacgttga tactgtgggc acttgcacgc
    13381 acacaagcat cgaccatgat taacagttcc attaggtggt tgttgacagg gaaacttgtt
    13441 gattggatga tgtaaacatc ataaccacgg acactttctt cgatatttac ttggatttct
    13501 ccgtctgaaa attgacgtga tgatagtttt ccaagtggga caccaacagc ttgggcaatt
    13561 ttctgtgcaa tctcttggtt agagttaagt gcgaaaagtt tcatgttttt tctatctgac
    13621 attatagacc gtcctctgta aactttataa atcctagtta tatttacctt acatatatga
    13681 actagggttt gtgtattttt atcttttcta ttttaccaaa aaatggagat tatttcagct
    13741 atttttcata cttttgacaa atcgaaccaa ttttgaagga gctttttggt aggaaatctg
    13801 atttttctct aaaaattgtc ggaaatcctg tttgccttgc tcatgatttt ccacttcaag
    13861 ctccaattcg taatctgtca tatcaaagta tcggctctga tccagtgcca tgagaccaat
    13921 agctgttttc atttcatagc gaagcgttgt tagacaacca agaacctgcc agttcttact
    13981 ttggatacca tgtttcgcca attcatccag tactagtcct tgaggaagtt cttccttact
    14041 cagatagttc tcagcatctt ttagttgcaa tttttggttg tattccatgt ttccaacact
    14101 ctgcgggact ttgagtgtca actcagccca gtcttcaaag gttcgaatgc gcatagcgac
    14161 tttcttttct cgcagttcaa aatcaggcgt gtctatgtag taatttgttt gaagaacagg
    14221 agtgacacct gtgaactggt cttttagacg attgtattca tcttttttca atagtgtttt
    14281 caattcaatt tctaaatgtt tcatttttct tacctttttt tatcgttgaa agcggattta
    14341 tggtataata agcattgtat ttattgtata tgaatctgga gaaaaaatca aagatatttt
    14401 tgacggataa tatgagaaca agggagaata tatgacctta gaatgggaag aatttctaga
    14461 tccttacatt caagctgttg gtgagttaaa gattaaactt cgtggtattc gtaagcaata
    14521 tcgtaagcaa aataagcatt ctccaattga gtttgtgacc ggtcgagtca agccaattga
    14581 gagcatcaaa gaaaaaatgg ctcgtcgtgg cattacttat gcgaccttgg aacacgattt
    14641 gcaggatatt gctggcttac gtgtgatggt tcagtttgta gatgacgtca aggaagtagt
    14701 ggatattttg cacaagcgtc aggatatgcg aatcatacag gagcgagatt acattactca
    14761 tagaaaagca tcaggctatc gttcctatca tgtggtagta gaatatacgg ttgataccat
    14821 caatggagct aagactattt tggcagaaat tcaaattcgt actttggcca tgaatttctg
    14881 ggcaacgata gaacattctc tcaactacaa gtaccaaggg gatttcccag atgagattaa
    14941 gaagcgactg gaaattacag ctagaatcgc ccatcagttg gatgaagaaa tgggtgaaat
    15001 tcgtgatgat atccaagaag cccaggcact ttttgatcct ttgagtagaa aattaaatga
    15061 cggtgtagga aacagtgacg atacagatga agaatacagg taaacgaatt gatctgatag
    15121 ccaatagaaa accgcagagt caaagggttt tgtatgaatt gcgagatcgt ttgaagagaa
    15181 atcagtttat actcaatgat accaatccgg atattgtcat ttccattggc ggggatggta
    15241 tgctcttgtc ggcctttcat aagtacgaaa atcagcttga caaggtccgc tttatcggtc
    15301 ttcatactgg acatttgggc ttctatacag attatcgtga ttttgagttg gacaagctag
    15361 tgactaattt gcagctagat actggggcaa gggtttctta ccctgttctg aatgtgaagg
    15421 tctttcttga aaatggtgaa gttaagattt tcagagcact caacgaagcc agcatccgca
    15481 ggtctgatcg aaccatggtg gcagatattg taataaatgg tgttcccttt gaacgttttc
    15541 gtggagacgg gctaacagtt tcgacaccga ctggtagtac tgcctataac aagtctcttg
    15601 gcggtgctgt tttacaccct accattgaag ctttgcaatt aacggaaatt gccagcctta
    15661 ataatcgtgt ttatcgaaca ctgggctctt ccattattgt gcctaagaag gataagattg
    15721 aacttattcc aacaagaaac gattatcata ctatttcggt tgacaatagc gtttattctt
    15781 tccgtaatat tgagcgtatt gagtatcaaa tcgaccatca taagattcac tttgtcgcga
    15841 ctcctagcca taccagtttc tggaaccgtg ttaaggatgc ctttatcggt gaggtggatg
    15901 aatgaggttt gaatttatcg cagatgaaca tgtcaaggtt aagacctttt taaaaaagca
    15961 cgaggtttct aagggattgc tggctaagat taagtttcga ggtggagcta ttctggtcaa
    16021 taatcaaccg caaaatgcaa cgtatctatt ggacgttgga gactacgtta ccatttacat
    16081 tcccgctgag gaaggctttg aaaccttgga ggctattgag catccattag atattctcta
    16141 tgaggatgac cactttctag tcttgaataa accctatgga gtggcttcta ttcctagtgt
    16201 caatcactct aataccattg ccaattttat caagggttac tatgtcaagc aaaattatga
    16261 aaatcagcag gttcacattg ttaccagact agatagggac acttctggct tgatgctctt
    16321 tgccaagcac ggttatgccc atgcacgatt agacaagcag ttgcagaaga aatctatcga
    16381 gaaacgctac tttgctttgg ttaagggaga tggacatttg gagccagaag gggaaattat
    16441 tgctccgatt gcgcgtgatg aagattccat tattaccaga cgagtggcta aaggcggaaa
    16501 gtatgcccat acttcataca agattgtagc ttcttatgga aatattcact tggtctatat
    16561 tcacctgcac actggtcgaa cccatcaaat ccgagtccat ttttctcata tcggttttcc
    16621 tttgctggga gatgatttgt atggtggtag tctggaagat ggtattcaac gtcaggctct
    16681 gcattgccat tacctatcct tttatcatcc atttttagag caagacttgc agttagaaag
    16741 tcccttgccg gatgatttca gtaaccttat tacccagtta tcaactaata ctctataaaa
    16801 actgtctcag agtataatta ttatcttaaa ggagaaaact catggaagtt tttgaaagtc
    16861 tcaaagccaa ccttgttggt aaaaatgctc gtatcgttct ccctgaaggg gaagagcctc
    16921 gtattcttca agcaacaaaa cgcttagtaa aagaaacaga agtgattcct gttttgcttg
    16981 gaaatcctga aaaaattaaa atttatcttg aaattgaagg aatcatggat ggttatgagg
    17041 tcatcgaccc tcaacattat cctcaatttg aagaaatggt ttctgccttg gtggagcgtc
    17101 gcaagggcaa aatgactgaa gaagatgtac gcaaggtttt ggttgaagat gtcaactact
    17161 ttggtgtgat gttggtttac ttgggcttgg ttgatggaat ggtgtcagga gcgattcact
    17221 caacagcttc aacagttcgt ccagctctac aaatcatcaa aactcgtcca aatgtaactc
    17281 gtacttcagg agccttcctc atggttcgtg gtacggaacg ttacctattt ggagactgtg
    17341 ccattaacat caatccagat gcagaagcct tggctgaaat tgccatcaac tcagcaatca
    17401 cagctaagat gtttggcatc gaacctaaaa ttgccatgtt gagctattct actaaaggct
    17461 cagggtttgg tgaaagcgtt gataaggtcg ttgaagcaac taaaattgct cacgacttgc
    17521 gtcctgacct tgaaatcgat ggtgagttgc aatttgatgc agcctttgtt cctgaaactg
    17581 cagctctgaa agctcctgga agtacggtag ctggtcaagc aaatgtcttc atcttcccag
    17641 gtatcgaggc aggaaatatc ggttacaaga tggctgaacg cctgggtggc tttgcggctg
    17701 taggacctgt tttgcaaggt ttaaacaagc cagttaatga tctttctcgt ggatgtaatg
    17761 cagatgatgt ttacaagttg accctcatca cagcagctca agcagttcat caatagtgaa
    17821 aactataaag cgatatacta tgctatactg tagttatgaa actatgtacg aaaagcactg
    17881 ccattaattc ctgagaacta aattactgat tggtgtcaaa aaggaaaact tccaagcgat
    17941 gatatcctgt ctatacacga cctatagaaa tctgtaatat acatgtccgt aaaacgataa
    18001 attccctttt tgattttaaa tgagtatgaa aagagaattt tttcatgaga aaacgcataa
    18061 tattaagtgt cttgacacct gctattatgc gttttctggc tctttgtcaa ctgtagtggg
    18121 ttgaagaaaa gctaagctcg agaaaggaca aattttgtcc tttctttttt gatgttcaga
    18181 gcgataaaaa tccgtttttt gaagttttca aagtttcgaa aaccaaaggc attgtgcttg
    18241 ataagtttga tgagattatt ggtggcttcc agtttggcgt tggaataagg taattgaagg
    18301 gcgttgacga ttttctcttt atctttgagg aaggttttaa acagagtctg aaaaagaggt
    18361 ggaaaagcaa gagctg
//
LOCUS       DAVKAU010000039        18052 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVKAU010000039 DAVKAU010000000
VERSION     DAVKAU010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.039"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            314..1360
                     /gene="pheS"
                     /locus_tag="VWX48_001498"
     CDS             314..1360
                     /gene="pheS"
                     /locus_tag="VWX48_001498"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU9172104.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKIISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1360..1869
                     /locus_tag="VWX48_001499"
     CDS             1360..1869
                     /locus_tag="VWX48_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9172105.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMQEEEIAAFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1946..4351
                     /locus_tag="VWX48_001500"
     CDS             1946..4351
                     /locus_tag="VWX48_001500"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU9172106.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVELPAAGLSK
                     IVVGEVLSCEAVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4419..5420)
                     /locus_tag="VWX48_001501"
     CDS             complement(4419..5420)
                     /locus_tag="VWX48_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9172107.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5568..5971
                     /locus_tag="VWX48_001502"
                     /pseudo
     CDS             5568..5971
                     /locus_tag="VWX48_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6097..6363
                     /locus_tag="VWX48_001503"
     CDS             6097..6363
                     /locus_tag="VWX48_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9172108.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            6624..8873
                     /gene="metE"
                     /locus_tag="VWX48_001504"
     CDS             6624..8873
                     /gene="metE"
                     /locus_tag="VWX48_001504"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU9172109.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8937..9803
                     /gene="metF"
                     /locus_tag="VWX48_001505"
     CDS             8937..9803
                     /gene="metF"
                     /locus_tag="VWX48_001505"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU9172110.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10488..12701
                     /gene="pnp"
                     /locus_tag="VWX48_001506"
     CDS             10488..12701
                     /gene="pnp"
                     /locus_tag="VWX48_001506"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU9172111.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12717..13334
                     /gene="cysE"
                     /locus_tag="VWX48_001507"
     CDS             12717..13334
                     /gene="cysE"
                     /locus_tag="VWX48_001507"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU9172112.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13346..14230
                     /locus_tag="VWX48_001508"
     CDS             13346..14230
                     /locus_tag="VWX48_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9172113.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERGTASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14312..15655
                     /locus_tag="VWX48_001509"
     CDS             14312..15655
                     /locus_tag="VWX48_001509"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU9172114.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15648..16034
                     /locus_tag="VWX48_001510"
     CDS             15648..16034
                     /locus_tag="VWX48_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU9172115.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16038..16922
                     /locus_tag="VWX48_001511"
     CDS             16038..16922
                     /locus_tag="VWX48_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU9172116.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17059..17493
                     /locus_tag="VWX48_001512"
                     /pseudo
     CDS             17059..17493
                     /locus_tag="VWX48_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17801..17971
                     /locus_tag="VWX48_001513"
                     /pseudo
     CDS             17801..17971
                     /locus_tag="VWX48_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5438 a         3476 c         4091 g         5047 t
ORIGIN      
        1 gctataaagt tagataagaa taagctaaca agcagaagta agataggtct tgcaagaatg
       61 gtaaaaatct gataaactaa gtagtaattg aataggaatc tgaaagacta gtagcccaag
      121 ggaagtatat cagggaggag agccgtgact gcaagctctc tatatgaaag ctgggtgaat
      181 tcacttgcgc atggatttag aaatgaaggt ctgacttgtc agatgaaaac ggatggtacc
      241 gcgtgtcaac gctccgagtg gagtttttgg catgtggttt tctttttatc tacgagagac
      301 tgatggagga aatatgtcaa ctattgaaga acaattaaaa gcgcttcgcg aagaaacgct
      361 gactagcttg aagcagatta ctgctggaaa tgaaaaagag atgcaagatt tgcgtgtctc
      421 tgtccttggt aaaaagggtt cgcttactga aatcctcaaa gggatgaaag atgtttctgc
      481 tgagatgcgt ccaatcatcg ggaaacacgt caatgaagct cgtgatgtct tgacagctgc
      541 ttttgaagaa acagctaagc tcttggaaga aaagaaagtc gcggctcaac tggctagcga
      601 gagtatcgat gtgacgcttc caggtcgtcc agttgcgact ggtcaccgtc acgttttgac
      661 acaaaccagt gaagaaatcg aagatatctt catcggtatg ggttatcaag tcgtggatgg
      721 ttttgaagtg gagcaagact actataactt tgaacgtatg aaccttccaa aagaccaccc
      781 agctcgtgat atgcaggata ctttctatat cactgaagaa atcttgctcc gtacccacac
      841 gtctccagtt caggcacgtg ctatggatgc ccatgatttt tctaaaggtc ctttgaagat
      901 aatctcgcca gggcgtgtct tccgtcgcga tacggacgat gcgacccaca gtcaccaatt
      961 ccaccaaatc gaaggcttgg tagttgggaa aaatatctct atggctgatc ttcaaggaac
     1021 gcttcagttg attgtccaaa aaatgtttgg tgaagagcgt caaattcgtt tgcgtccatc
     1081 ttacttccca ttcacagagc catctgttga ggtggatgtt tcttgcttca aatgtggtgg
     1141 agaaggctgt aacgtatgta agaaaacagg ttggatcgaa attatggggg ccggtatggt
     1201 tcacccacgt gtccttgaaa tgagtggtat cgatgcgact gtatactctg gctttgcctt
     1261 tggtcttgga caagagcgtg tagctatgct ccgttatgga atcaacgata tccgtggatt
     1321 ctaccaagga gatgtccgct tctcagaaca gtttaaataa tgattagaaa agtagaaatg
     1381 gcagatgttg aggtgttggc taaaattgcc aaacaaacct ttcgtgaaac ctttgcgtat
     1441 gataatacgg aagagcagtt acaggaatac tttgaagagg cttatagtct gaaaactttg
     1501 tcaactgagt tgggaaatcc tgactctgaa acctatttca ttatgcagga ggaggagata
     1561 gctgcttttc tcaaagtcaa ctggggaagt gctcaaactg agagagaatt agaggacgct
     1621 tttgaaattc aacgcctcta tgtgctacaa aaattccaag gatttggact aggtaagcaa
     1681 ctgtttgaat ttgctcttga acttgctaca aaaaatagtt tttcttgggc ttggctaggt
     1741 gtttgggagc ataatacaaa agctcaagcg ttttataacc gatatggttt tgaaaaattt
     1801 agccaacatc attttatggt tggtcaaaaa gtagatacgg attggttact gagaaagaaa
     1861 ttaaggtaag aagaggattc ttctattgaa atgataggaa aggaaaagaa ctagagtgac
     1921 aactgtcatt ctggagaact aaattatgct tgtatcttat aaatggttaa aagaattggt
     1981 ggacattgat gtgccatcac aagagttggc tgaaaaaatg tcaactacag ggatcgaggt
     2041 agagggtgtc gaattaccag ctgctggtct ctcaaaaatt gtcgtcggtg aggtcttgtc
     2101 ttgcgaagct gtgccagaga ctcacctcca tgtttgtcag attaacgttg gcgaagaaga
     2161 agagcgtcag atcgtttgtg gtgccccaaa tgtgcgtgct gggatcaagg tcatggtggc
     2221 tcttccagga gctcgtatcg ctgataacta caaaatcaaa aaaggaaaaa tccgtggttt
     2281 ggagtcactt ggaatgatct gttcacttgg tgaattggga atttctgact cagttgtgcc
     2341 taaggaattc gcagatggca tccaaatctt gcctgaagat gccgtgccag gtgaggaagt
     2401 cttttcttac ctagacttgg atgatgaaat catcgaactt tccatcacac caaaccgtgc
     2461 agatgccctt tctatgtgtg gagtggctca cgaagtggca gccatctatg acaaggcagt
     2521 caactttaaa aaatttactc taacagaaac taatgaagct gcggcagatg ccctttctgt
     2581 cagcattgag acagacaagg cgccttacta tgcagctcgt atcttggaca atgtgactat
     2641 cgcaccaagt ccacaatggt tgcaaaacct tctcatgaac gaaggcatcc gtcccatcaa
     2701 taacgttgta gacgtgacaa actacatcct gctctacttt ggtcaaccta tgcatgcttt
     2761 tgacttggac acatttgaag ggactgacat ccgtgtgcgt gaagcgcgtg atggtgaaaa
     2821 attagtgacc ctggacggtg aagaacgaga cttggctgag acagacctcg tgattacagt
     2881 tgctgacaaa ccagtagccc ttgccggtgt tatgggtggt caggctacag aaatttctga
     2941 aaaatctagt cgtgttatcc ttgaagctgc tgtttttaat ggcaaatcta tccgtaagac
     3001 aagtggtcgc ctgaaccttc gttctgagtc atcttctcgc tttgaaaaag gaattaatgt
     3061 ggcaacagtt aatgaagccc ttgatgcggc agctagcatg attgcagagc ttgcaggcgc
     3121 gacggtgcgt aagggtatcg tttcagcggg tgagcttgat acctctgatg tggaagtttc
     3181 ttcaaccctt gctgatgtta accgtgtcct cggaactgag ctgtcttatg ctgatgtaga
     3241 agacgtcttc cgtcgtcttg gctttggtct ttctggaaat gcagacagct ttacagtcag
     3301 cgtaccacgt cgtcgttggg atatcacaat cgaagctgat ctctttgaag aaatcgctcg
     3361 tatctatgga tatgaccgct tgccaaccag ccttccaaaa gacgatggta cagctggtga
     3421 attgactgtg atacaaaaac tccgccgtca agttcgtacc attgctgaag gagcaggttt
     3481 gacagaaatc atcacctatg ctctgacaac tcctgaaaaa gcagttgagt tcacagctca
     3541 accaagtaac cttactgaac tcatgtggcc aatgactgtg gatcgttcag tcctccgtca
     3601 aaatatgatt tcagggatcc ttgataccgt tgcctacaac gtggctcgta agaataaaaa
     3661 cttggccctt tatgagattg gaaaagtctt tgaacaaaca ggtaatccaa aagaagaact
     3721 tccaaatgag atcaacagct ttgcctttgc cttgacaggc ttggttgctg aaaaagattt
     3781 ccaaacagca gcagttccag ttgatttctt ctatgctaag ggaatccttg aagccctatt
     3841 tactcgtttg ggactccaag taacctatac agcaacatct gaaatcgcta gccttcatcc
     3901 aggtcgtaca gccgtgattt cactcggtga ccaagttctt ggtttccttg gccaagtgca
     3961 tccagtcact gccaaggctt acgatattcc agaaacgtat gtagctgagc ttaacctttc
     4021 agccatcgaa ggggcgctcc aacctgctgt tccatttgtg gaaatcacca aattcccagc
     4081 agtcagccgt gacgttgccc ttctcctcaa ggcagaagtg actcaccaag aagttgtaga
     4141 tgctatccaa gctgccggcg tgaaacgttt gacagatatc aaactctttg acgtcttctc
     4201 aggtgaaaaa ctgggacttg gtatgaagtc aatggcttat agcttgacct tccaaaatcc
     4261 agaagacagc ttaacggacg aagaagtcgc acgctacatg gaaaaaatcc aagcgtctct
     4321 cgaagaaaaa gtcaatgcag aagtgcgtta aacgatagta ggatacaaat tccccctcta
     4381 gtttatgaac actagagggg tgattttata taaaataatt aaaatgtgat ttctgtaaaa
     4441 atacatctat gatcagagtt ttgaaaactt acaatgtcta aatctttaac atagtagtgg
     4501 tttttaggca ataaaatatg atctattgtt gcattaaaaa gttttggact ttggctattc
     4561 caagttcctc tttcaaaagg tggcagtaca tttaatgcgt ccctatgaga gcttattttt
     4621 gcaagtgctc catgacgcat agttgcatta aaatcacctg caataatagc ctttggatat
     4681 tttgaagcca attgattatg aatgatgttt aagtcttgct tccagatttc cattaaacct
     4741 ggcagaggag gagcagtatg caaggcaatg atatctggta tattttgttt tctcgaatgt
     4801 aatacaattg tcccgaaccg tgttgtatga aaagttttag cttctgtata gaaaccataa
     4861 cttttcttga caatcacagt cacaggagct attccactat tggtaggtgg agaagtgaaa
     4921 atatcatagt tggccataga aagtccaact tgatgaaaca atagtttgat tctctggttt
     4981 tcttgctcac ctctgatatt ggtagctagt tcagggaata tagccatatc ggcgtcaaaa
     5041 tggctaaaaa ttcgctcaat atgttgtgct tctatttgat tagcgacgtt ccaagttact
     5101 aattttaagg ttttagtctt atttgatgca gaagaaaggg ttttatctgt tccgaataat
     5161 agtaatatga gcgatagtaa gagcaaaatg ccagagtaaa accgtatttg tttatttttc
     5221 ttgtaaaaag atagggaaaa aaatacgaaa cttaaaatag aagccatagt tgcagtagct
     5281 aaggggaagg cataaatctg tgccaagata ggttgggtag atagccaaat attaagatta
     5341 gaagatggaa aaaaagaata agctatgata gggataacaa agagaatgac cgaaagggca
     5401 gagagaaatg ttttaatcat tgtgtgagta cctcaatttg caatggttgc tcggagctaa
     5461 tgtgacttta cttgattgat attctttttc ttgtcttcct tatagattaa gtacaaccca
     5521 agtaaaaaaa gtccaattta agattgaaat gattaaaagg cacagaaatg caagacaatt
     5581 atactacaaa aggcaaacat ttgacaatcg atagccgtcg cttaatcgaa cgatggaaaa
     5641 aagaaggaaa atcaaataga gaaattgcct ctctacttgg aaaagctcct caaactatcc
     5701 acactgaaat aaagcgtggg acagtccgac aatgtcttgg aaaagggcgc ttcaaagaga
     5761 tttattctgc cgactacgct caacagtctt aagaaactaa aggaaaagat tctccactat
     5821 acataaccaa aaattttcgc ctgaaatgat ggttatggct aaaggggtta acgtgggaat
     5881 ttcaaccatt tactattgga ttcatcgtgg aaaattgggg ttaagcaagc aggatctgct
     5941 ttatcctaga aaaggaaaat cgcttaagaa ataggctagc accaacttta aacccactgg
     6001 tcaatctatc gaatcataat tcgctcattt ttttaaaaat acatagacgt aaaaaaaaga
     6061 gggttaagtg atgaagaata gtgctattgg gagtaattgg aaggatgtcc atctgagctc
     6121 tttagcaagg aggaaatcct tgaaagtgat atgcgagtgg ctatcatgag cgagttgatt
     6181 gaggctaggt atgaacaagg aatcagtcag aaaaagctgg aagaagtcag tggaataagc
     6241 cagcctgtca tagctaggat ggagacagga aagactagtc ctcagttgga tacagtctta
     6301 aaagtcctag ccagtttagg aaagacacta gcaatcgtcc cacttgaaca gggaaaaagt
     6361 tgactagaat cagttatagt cttttctaat aacaggtcat agtcacttat aagaattact
     6421 aataacatgt tttagtattc taattggaat atagctgtaa agtaagaatt acaaaggatt
     6481 tgagacgttt gcttcaagtc tttttctttt gtccgaaaca gatatatagt ttcaaactat
     6541 atcaaaccct aattttttac aattatacag acgctttctt ttctgttaag atagtttcaa
     6601 caacaaattt tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttgggcg
     6661 aattccgtga attaaaattt acaactgaaa aatactttag aaaagaaatc tcagaagaag
     6721 aacttttagc agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag
     6781 gcatcactga aatcccatca aatgactttt ctcactatga taacttccta gatgcggctt
     6841 tccttttcaa cgtagtgcct gcctcagttc aaaacttgga cttgtctgac cttgagcgct
     6901 acttcgcttt gggacgtggt taccagggag aaaaagggga cgttcgcgcc cttccaatga
     6961 agaaatggtt caacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag
     7021 taaaattggc tggtcacaag attttcgatg agttccaaga agccaaagaa cttggattga
     7081 acactcgtcc tgttcttgta ggtcccttca ctttccttca attgtcagac tttgaagaag
     7141 gcgtgaaagc agacgacttc gtagatagct tagtggctgc ttaccaagaa gtttttgcta
     7201 aattggctga acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact
     7261 tgacagctga agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa
     7321 aaggtcttga agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc
     7381 ttgtaaactt accagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg
     7441 aactcgttaa aggtggcttc ccagctgaca agactctcta tgtaggtatt gtcaatggta
     7501 aaaacatctg gcgcaacaac tacgaaaaga gcttggctgt tcttgagcaa atcccagctg
     7561 aaaacatcgt tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg
     7621 aagaatttga accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa
     7681 tccgtgactt ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag
     7741 aactctttgc gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct
     7801 tgacagacgc agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag
     7861 aagctttcaa acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag
     7921 aagttcgtgc caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg
     7981 ctttccttgc tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg
     8041 tccttgttca cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt
     8101 caggatacct cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac
     8161 caccaatcat ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct
     8221 atgcacaaag tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc
     8281 ttaactggtc attcccacgt gaagacatct ctatcaagga ttcaactctc caaatcgccc
     8341 ttgctatcaa ggatgaagta cttgaccttg aagctgctgg tgtgaaaatc atccaaatcg
     8401 acgaggctgc tcttcgtgaa aaattgccac tccgccgtag cgactggtac gaagactacc
     8461 ttgactgggc tattcctgcc ttccgcttgg tacactcaac agtagcgcca gacacacaaa
     8521 tccacactca catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg
     8581 atgcagacgt tatttccttt gaagctagcc gttcaaacct tgaaatcttg gacgaactca
     8641 aagcgaaaaa cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg
     8701 taccaaatga aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca
     8761 agaaagtttg gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag
     8821 aaagcttgat ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga
     8881 tttctctcca tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt
     8941 cacgccaaac accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg
     9001 ataacattat ttcagccttg caggatatgc aggagttggc tccccatttt atcagtgtaa
     9061 ctgccagcaa taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc
     9121 aaaatgattt ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca
     9181 aggttgctga aactattgct gacttggaca aagttggggt gcagaaaatc ttggctcttc
     9241 gtggggatat tattccagac gtggaaccac aaaaggattt ccgctatgca accgacttga
     9301 ttgagtttat caaggaacaa acccctcact ttgatattat tggagcttgc tatccagaag
     9361 ggcatccaga ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg
     9421 caggctgttc gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc
     9481 aggacaagtg tattttggct gggattgatg ttcccattca tgcaggaatt atgccaattc
     9541 tgaatcgaaa tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca
     9601 aatttaaagc catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac
     9661 ttgcctatgc agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc
     9721 tctatacgat gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt
     9781 ttaatcacca gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt
     9841 tcctttttaa tggcaaagac ctcacttttt aagaaaaata tgataaaata gattctgtac
     9901 gtacttgata caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa
     9961 cgacacgagt gagtcaaatc gatgttattt gacgaaagag ttagtaaagc atttagctaa
    10021 tcgcccgata gcaattagcg tgaaaggttt agatacttta atattaaacc tttctaatga
    10081 tgtatcttga aaactgaact tgcctacaac tctgtggaaa aagataaatc tccctaggag
    10141 cagtcgctcc gtcgttcgat ttcctatctt cctttgagtt gcttgacggc ttggtatctt
    10201 gatgacttga attttggtct catttcttag gaaaaaagat aagcttccta gcactcgtcg
    10261 agtgcgacgt caccttccta tttttctaca gaaatgttcg gcaagccgaa ccgtccaaaa
    10321 tatcttgtgt aattgaacac ggccgaaaag ctgtgtaaaa aagataaact gtcttgtctt
    10381 catcgaagac ttcgtcagtt tcctattttt actttgcttt tgacgtcctt ggtatcttga
    10441 tctttgtagg caaggcgtat aatttcatca atccaaaggg gattaaaatg gcaaaacaag
    10501 tgtttcaaac gacttttgcg ggtcgtgagt taattgtaga gactggtcag gttgctaagc
    10561 aagcaaatgg atctgttgtc gtacgttacg gtgagtcaac tgtcttgact gctgccgtta
    10621 tgtctaagaa aatggcaact ggggatttct tcccactcca agtcaactac gaagaaaaaa
    10681 tgtatgcggc tgggaagttt cctggtggct ttatgaaacg tgaaggacgt ccttcaacag
    10741 atgcgacctt gacagcgcgt ttgattgacc gtccgattcg tcctatgttt gcggaaggtt
    10801 tccgtaatga agtccaagtc atcaatacag tgctttctta tgatgaaaat gcatctgcac
    10861 caatggctgc tatgtttggt tcatctttgg cactgtctat ttcagatatt ccatttgacg
    10921 gaccaattgc tggggtacaa gtgggatatg tagatggcca aatcatcatc aacccaagtc
    10981 aagaacaagc agagcaatct cttcttgaat tgacagtagc tggaaccaag cacgctatca
    11041 acatggtaga gtctggtgcc aaagaattgt cagaagaaat catgttggaa gcgcttctta
    11101 aagggcacga agctgtcaaa gaattgattg ccttccaaga agaaatcgtt gctgctgtcg
    11161 gtaaagaaaa agcagaagtg gaattgcttc acgtggatgc tgaattgcaa gctgaaatca
    11221 ttgcagccta caacagtgac ctccaaaagg cagttcaagt agaagagaaa ttggcccgtg
    11281 aagctgcaac tcaagcagtg aaagaccaag tgactgccgt ttacgaagaa aaatatgcgg
    11341 accacgaaga atttgaccgt attatgcgtg atgtggctga aatcttggaa caaatggaac
    11401 acgcagaagt gcgacgttta attacagaag acaaggtgcg tcctgatggt cgtaaggtcg
    11461 atgaaatccg tcctttggat gcggttgttg acttccttcc tcgtgtacat ggttcaggtc
    11521 tctttactcg tgggcaaact caagctcttt cagtcttgac cttggctccg atgggagaaa
    11581 ctcaaatcat tgatggtttg gatccagagt acaagaaacg ctttatgcac cactataact
    11641 tccctcaata ttctgtaggg gaaacaggtc gttacggtgc gccaggtcgt cgtgaaatcg
    11701 gtcacggtgc ccttggtgag cgtgctcttg ctcaagtctt gccaagcttg gaagaattcc
    11761 catacgctat ccgtctagta gcagaagttt tggaatcaaa cggttcttca tctcaagctt
    11821 ctatctgtgc gggaactctt gcccttatgg ctggtggtgt gccaatcaag gcgccagtag
    11881 ctggtattgc tatgggactt atctcagatg gaaataacta cacagtattg acagatatcc
    11941 aaggtttgga agatcacttt ggagatatgg acttcaaggt tgcaggtact cgtgatggga
    12001 ttacagccct tcaaatggat atcaagattc aagggattac tgcagaaatc ttgacggagg
    12061 ctcttgctca agccaagaaa gcgcgttttg aaatccttga tgtcattgaa gcaaccattc
    12121 cagaagttcg tccagaattg gctccaactg ctccgaaaat tgatacgatc aagattgatg
    12181 tggacaagat taagattgtc atcggtaagg gtggagaaac catcgacaag attatcgctg
    12241 aaacaggtgt taagattgat atagacgaag aaggaaatgt gtctatctac tctagtgacc
    12301 aagatgctat taaccgtgcc aaagaaatta ttgctggttt ggttcgtgaa gccaaagtgg
    12361 atgaagttta ccgtgctaaa gtcgttcgta tcgagaaatt tggtgccttt gttaacctct
    12421 ttgataagac agatgccctt gttcatatct ctgagatggc ttggactcgt accaatcgtg
    12481 tagaggattt ggtagaaatc ggggatgaag ttgatgttaa ggttatcaag attgatgaaa
    12541 aaggccgtat cgatgcctct atgaaggctc ttctacctcg tccgccaaaa cctgagcatg
    12601 atgaaaaagg tgaaaagtct gagcgccctc accgcccacg tcatcacaag gatcacaaac
    12661 ctaagaaaga atttacagaa acaccaaaag attcagagta agaaaaggag aaatgtatgg
    12721 ggtggtggcg cgaaaccatt gatatcgtaa aagaaaatga tccagcggcc cgcaccactt
    12781 tggaggtttt gctgacttat ccaggtgtca aggccttggc ggcccaccgt ctctcgcatt
    12841 ttctctggaa gtacgacttc aaactcttag ctcgtatgca cagtcagttt tggcgctttt
    12901 ggactcagat tgagattcat ccaggagccc agattgattc aggtgtcttt attgaccatg
    12961 gttctggtct ggtgattgga gagacagcga ttgttgaaaa aggcgttctt ctctatcacg
    13021 gagtgactct cgggggaaca gggaaagact gtggcaaacg ccatccgact gtacgaaagg
    13081 gagccctcat atcagcccat gcccaagtta tcgggcctgt ggaaattggt gaaaatgcca
    13141 aggtcggtgc tgcagcagtt gtcgtagcag atgtacctag tgatgtgacg gttgtcggta
    13201 ttccggccaa gattgtccgt cttcatggta agaaagatga gcctgttatt cacgaagtcg
    13261 aagaaaaacg ggagtattat gtcaataaac tcgagcaggc taaagatgcc agtcacagat
    13321 cgtctggttt gtagaggata cctatatgat tcaagcaaga aacaagttaa gccaagaaga
    13381 gctatctgag gcgaaaaaag taattaactg ttgccaaaac tatgacggta cctatcgcga
    13441 tccctatctc tctaacatgc ttaattttga tccaaacatg cccgcctttt tcctttatta
    13501 tgaaaaaggc gaacttgttg gtttattaac tgtctatgca gatgaccaag atgtagaagt
    13561 gacgatactg gttcatccag gtcatcgccg tcaggggatt gcgcgtgcat tgtttactag
    13621 ttttgagaga ggaacagctt ctttccccat tcggtcagtc acttttcaga cagaacgtat
    13681 ttttttagag aatcatcctg actttgccag taactgggga ctaatagagg atgaagagac
    13741 agaaacttgg ttaggtaagg atagaagacc ttatccgtta gcaaatgttt cccatcttga
    13801 agttttgtta gcagatagtt cgtatcagga tcaaattagt caattaaaat ttcaggcatt
    13861 ttcagaggaa catgaatcga gagaagttgt ggatagatat gtcgctgaag ctctgaagga
    13921 tccagaaagt cgcttatata ttttattaaa agacggtcag gttattggga cttgtacggt
    13981 tgatttatcg actaatacga attacttcta cggtttagca atattggaac ctgaacgtgg
    14041 aaaaggctat ggaagctact tagcaaaatc cctcgtcaac caactaattg agcaaaatga
    14101 caaggaattt cagattgcag tggaagatag caatgtaggt gccaaacgtt tgtatgaaaa
    14161 aattggcttt gtcaaacaga ctcaggtggt ttatctgaat gagaaaggag caagggattc
    14221 cgaagtgtag agatattcgg actgaaattt acttgaactt ttagtgatga aactaattgt
    14281 tcttggattt cagctttcct gattatgatt tatgattaaa atctatgaca ccatgtctcg
    14341 tgatttgcga gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc
    14401 aacggtgtac aactatatcc acgtgggaaa cgcccgttcg acggtagctt ttgatacgat
    14461 tcgtcgctat tttgagtacc gtgggtataa ggttgcctat atttccaatt ttacagatgt
    14521 ggatgataag attatcaacc gtgccaggga agaaggcatc acgcctcagg aggttgcgga
    14581 taagtacatc gctgcctttc gtgaggatgt gacggccttg ggcgtgaaac ctgcgactcg
    14641 ccatccgcgt gtagtggagt ttatggcaga catcatccgt tttgtggaag acttgatcga
    14701 gaaaggcttt gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa
    14761 ctatgctaaa ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac
    14821 cgatgaagaa acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa
    14881 accaggtgag atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga
    14941 gtgttcagtc atgtcgacag agattttagg tgataccatt gatatccacg gtggtggagc
    15001 tgacctagag tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa
    15061 ggcttttgct aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc
    15121 taagtccttg ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt
    15181 acttcgtttc ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc
    15241 agttcgcgat gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac
    15301 aggaaacgtg gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga
    15361 tgaagatttt aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa
    15421 ctcagggaac tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg
    15481 aattgtcttt gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca
    15541 agaggcgcgt gccaatcgag actttgagac agcagaccaa atccgtgacc aattggttac
    15601 tcaaggaatt aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca
    15661 atctcattaa cgggattgcg ctagcctttg agggggatgc ggtgtattct atgtatattc
    15721 gccgtcacct catcctcaaa ggtatgacca aacccaataa actccatcaa gaagcaacca
    15781 agtatgtgtc agccaaggct caggctcgcc tgattgctct catgttggag gagcaggtcc
    15841 taacggaaaa agaagaagaa atctacaaac gtggccgcaa taccaatagc cacacaaagg
    15901 ctaaaaatgc agatgtcgtg acttatcgta tgtccacggg atttgaagcg gttatgggct
    15961 atctccatat gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa
    16021 aagtggaggg ctagaacatg agggaaaaag aactacaaga ctggtttcct gaggctcgga
    16081 tttcagacca accagtagag aaagagggct atctcacgct ccctttagct tctcagcagt
    16141 ggattttgct ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga
    16201 cccagcagga gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gaaggcaagg
    16261 gacaggcacc gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc
    16321 agcaggaaaa tctggcttct tggctagata tgatgcggac tctttttccg aattgtcaga
    16381 cagtgctaca ggtcggatct caggattatg ttttcgtgct tcaacaagac aaatacactt
    16441 ctgtaagaga tattttaagt gatacgattg aagcggttga gtatgacttt ggacttcgtc
    16501 tttctatcat gttgggtcag gtttggtctc agacgggaca tcaagcccta tcagacttaa
    16561 tcaaagctga gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata
    16621 ctttttctca gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatca
    16681 aggaatgtct acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc
    16741 tttgggaaaa tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt
    16801 ctctccaata caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga
    16861 ccgacctgac cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt
    16921 aaagaagtta atatttggag aagaggatgg ccatcttctc catttttatg tgcagagtta
    16981 tagtggcttg atgctgggaa agtacactgt gactgctaaa acattcctag aagttgcttt
    17041 gatttcccta atctatttat gtgaatttta tgttatttta ctataacagt tgttgctaag
    17101 ctaaataata gtggggaagt ttatttagac gtaagcattg aagataatca gggaggtagt
    17161 gggtataatt tcagttctgt ttcaagtagc tcacaaacag ctaaatatga aggaactggt
    17221 tataataaca attcatcatt atatataacg attgataaaa cgtctgatgc aacagctctt
    17281 ttgaaattaa agttgaataa tgttgataat caacctgcta ctgaagttcc tagttcagga
    17341 attactgtaa aattaaatgc taaagataat gctggaaact ggacaagtgc ttcgaataaa
    17401 aaagaagtaa cagtaaaaat tgtttctgct aaaccgacat atccagacaa aattttagtg
    17461 aaaaatcctg ataatataaa agatacagaa aaaaatgcca ttattgaaaa attgaaagag
    17521 gcaaataaaa atcatccagc aggagctcca acctttgcta aaggtgaagg agagcatgca
    17581 aatgatattg tagcaactta ttcagatggt acaacttatt atgtaccgtt aaatgatgtg
    17641 acaaaatatg cgaggtagtg gctgtaccac tcacttattc acctccccgt gatttgtagt
    17701 agtgataggc tttctcacta ttattataaa acaaaataaa gatcacaaca ctttttcatt
    17761 ctgtgttgtg ccttgagtga aacgaaagga atgaattata aatatgaaaa gtatagtcac
    17821 taacatagat gagcgcttgc gtactcgcct acgagtgatt atctggaagc aatggaagaa
    17881 gaaatcgaga cgattatggg gattgcttaa gttaggggtt cctaaatgga tagcagataa
    17941 ggtatctggc tggggcgacc actatcaatt atattaaaat gaaataagaa taggacgaat
    18001 cgatcaggga agtcaaatcg atttctaaca atattttaga agtagaggta ta
//
LOCUS       DAVKAU010000040        16752 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVKAU010000040 DAVKAU010000000
VERSION     DAVKAU010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.040"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(105..665)
                     /locus_tag="VWX48_001514"
     CDS             complement(105..665)
                     /locus_tag="VWX48_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172117.1"
                     /translation="MALFIAVVNNNITSLPSIALSLERENVDFLKSLPFDFARYVKVK
                     FWIIFAVQSFLPVLTLLGLSLYLGLPILSMIYLIVAWILASVILSCHHYFKDVKNLST
                     NWSSITDLVNRSNGIVAIVLLFILLFIYSAILMALVIGSIFLVQSLSPILAISLGVGA
                     LILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(637..1749)
                     /locus_tag="VWX48_001515"
     CDS             complement(637..1749)
                     /locus_tag="VWX48_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172118.1"
                     /translation="MRLKVIKKLVDINILYSSKEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFVVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPFFYSSLYSSCQ"
     gene            complement(1730..2479)
                     /locus_tag="VWX48_001516"
     CDS             complement(1730..2479)
                     /locus_tag="VWX48_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172119.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSSSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            2659..4113
                     /locus_tag="VWX48_001517"
     CDS             2659..4113
                     /locus_tag="VWX48_001517"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU9172120.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVKLGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4203..6821)
                     /gene="alaS"
                     /locus_tag="VWX48_001518"
     CDS             complement(4203..6821)
                     /gene="alaS"
                     /locus_tag="VWX48_001518"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU9172121.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESAFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELALIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(6843..7328)
                     /locus_tag="VWX48_001519"
     CDS             complement(6843..7328)
                     /locus_tag="VWX48_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU9172122.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEILESQS
                     H"
     gene            complement(7603..7842)
                     /locus_tag="VWX48_001520"
     CDS             complement(7603..7842)
                     /locus_tag="VWX48_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172123.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8095..9165)
                     /locus_tag="VWX48_001521"
     CDS             complement(8095..9165)
                     /locus_tag="VWX48_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9172124.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKELQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKKLLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9162..9935)
                     /locus_tag="VWX48_001522"
     CDS             complement(9162..9935)
                     /locus_tag="VWX48_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9172125.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(9932..10738)
                     /locus_tag="VWX48_001523"
     CDS             complement(9932..10738)
                     /locus_tag="VWX48_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9172126.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10719..11876)
                     /locus_tag="VWX48_001524"
     CDS             complement(10719..11876)
                     /locus_tag="VWX48_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172127.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(11935..12885)
                     /gene="murB"
                     /locus_tag="VWX48_001525"
     CDS             complement(11935..12885)
                     /gene="murB"
                     /locus_tag="VWX48_001525"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU9172128.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(12997..13754)
                     /locus_tag="VWX48_001526"
                     /pseudo
     CDS             complement(12997..13754)
                     /locus_tag="VWX48_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(13764..14495)
                     /gene="budA"
                     /locus_tag="VWX48_001527"
     CDS             complement(13764..14495)
                     /gene="budA"
                     /locus_tag="VWX48_001527"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU9172129.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14637..15908
                     /locus_tag="VWX48_001528"
     CDS             14637..15908
                     /locus_tag="VWX48_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU9172130.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKLSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(15928..16743)
                     /locus_tag="VWX48_001529"
     CDS             complement(15928..16743)
                     /locus_tag="VWX48_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9172131.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKDQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTNLKSANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
BASE COUNT         5050 a         3769 c         3304 g         4629 t
ORIGIN      
        1 ccctatatat ttttgattac caatcttaat catttacaac tacattctaa caaactataa
       61 aagcgtttgt cgaattgaat ttatcaagca agcgaccaac cagctcatct tttttctatt
      121 tctgccaata tgcgtgacag gtaataatga tagccaaaaa tagcaagagc aagcaggagg
      181 ataagagctc ctactcccaa gctgatggca aggatagggg agagagactg aaccaagaat
      241 atactcccaa ttacaagggc catcaggatt gcactataaa taaacaataa aataaacaat
      301 aaaactatgg cgactatgcc atttgaacga ttcaccaggt ccgtaatgct actccaattg
      361 gttgacagat ttttcacatc cttaaaataa tggtgacaag aaaggatgac actggcaagg
      421 atccatgcca caataaggta aatcatcgaa aggatgggca agcctagata tagagaaaga
      481 ccaagtaaag tcagaactgg taaaaaggac tgaacagcaa agataatcca aaatttcact
      541 ttcacataac gagcaaagtc aaagggtaaa ctcttcagaa aatcaacatt ttccctctcc
      601 aaggacaagg caattgaagg caggctggtg atattgttat tgacaactgc tataaagaga
      661 gctataaaaa aagggtaacc agtatggagg atgaatgtct ggaactatct gagaatctcg
      721 gattttggaa atcagaccga tcatcatgag ataaggaagg aaagcacttg taaaaagcac
      781 tgtaaccacg ccagtcccct gtcccaagag ggtgaggtgg tagcgtaaaa ccatgcggaa
      841 aaatcccttt ttagtggttg aaattctctc cttgctgcga cgttcttttt tgaccttctc
      901 ctcactatta agcaggatca cgtcataaaa acgaggaagg accttctttt tggtcagata
      961 aagcaggaag agagttagtc ctatccaagc gagcagaccc aatatggctt ctattgaaaa
     1021 aggctccact gctattttgt aaaagatatg aagaggataa aggagaaatg gaatgtctct
     1081 aactttgtca acaatacttc caaaagtcga ctgaagaaag aagataaata ttaaaggtat
     1141 gagaactcct atcccaatca tcacattcga aaaaatagac tgatactttc tgaagaccct
     1201 agtctgagcc aagaaatgta ctgccactac cgtcactaaa gtaacagaga caaataataa
     1261 ggtcaaggac agtagcatca aaggcaaacc cagccaaaga gaaggagcta gactaatata
     1321 gagggctaga aaataagcta ggattggtac aattccagtt agagctggca agaggacaga
     1381 cagtccttta gcaattataa tctctgattc tttaaaagca tagggactat aggaggccag
     1441 gtccttactc tcataaaaga cattgtaaaa tgcagttaaa gaagttgaaa aggcaatcac
     1501 tagtaaaata gcaaccacga aactaaaata aacaggcatt tcctcaaaag gaaaatgaat
     1561 ggctatagta ctaaaaaaga tgagcatcaa gagactggaa aaaatgtaag aacttaggac
     1621 tctagcggaa acatttactt tttttccagt atttttagct tgcttctttc gtaggttagc
     1681 cagattagct tctttagatg aatagaggat attgatatca actaattttt taatgacctt
     1741 gagacgcatc tgaaacctcc tcttttctac cagcaaggct aaggtagata ctttccaaag
     1801 actggtctgg gttgtctttt ctcaagtcct ctaccttacc acaataaatc aaatgcccct
     1861 ttttcaaaat agcaatccga tcacagactt gctcagctac ctctagcaca tgagttgaaa
     1921 acaaaactgt cttacctttt tgcgcatgct ccttcatcat ttgcttcaaa tcaaaggcag
     1981 cctggggatc caaaccagtc aagggttcgt ccaagaccca aatatcagga tcagacaaga
     2041 gtgccccgat gacaaaaact ttctgacgca ttccatgaga aagggtttca ataacctgat
     2101 aacgattttc agcaaaatca aaaacgttca ataacctagc taaactagct tccaagtcag
     2161 agctgctcaa atcataggat gaagcaatca attcccaaaa ttcattggcc gttaaacgta
     2221 aaaataagtc aggcgaatct gctacgtagc caatctttcg tttgatcgcc aagcgatttt
     2281 ccgataactc ctgaccatct accaaaatac gaccactgct gggtgaaatg atactgacta
     2341 gggattttat ggtggtcgat tttccagccc cattatgacc aatcaagccc ataatctctc
     2401 cattttcaat ctgcaaattg agattactca aggcctcttt atcaccatac aacttactaa
     2461 cattttgaaa ttcaatcatg ggatgactcc tatctttatc tatattaaat actattatac
     2521 tagcactttg atacaaaaaa atcaacactt tattttaagt agatacaata gtttccttct
     2581 attcttacgc aaacgtttgc gctaaccaat actttatgat agaataaaga acaagattga
     2641 caagtaagag gaaaaatcat gcaaaatcaa acgctcatgc aatactttga atggtatctg
     2701 ccccacgacg gtcagcactg gacgcgtctg gctgaagatg ctccacacct agctcatctg
     2761 gggattagcc acgtctggat gccaccagct tttaaggcaa ccaatgaaaa agatgtcggc
     2821 tatggtgtct atgacttatt tgacctagga gagtttaacc aaaaagggac tgtccgcacc
     2881 aagtatggtt tcaaagaaga ctatcttcaa gccattcaag ccctaaaagc acagggaatt
     2941 caacctatgg ccgatgtggt tctcaatcac aaggctgcag ccgatcacat ggaagccttt
     3001 caggttatcg aagtggatcc tgtagaccgt acggttaaac ttggagaacc cttcaccatc
     3061 aatggctgga ctagctttac cttcgatggt cgccaagata cctacaatga cttccactgg
     3121 cattggtacc acttcaccgg tacagactac gatgcaaaac gccgtaagtc tgggatttat
     3181 ctcatccaag gggacaacaa gggctgggct aacgaggaat tggtcgataa cgaaaacgga
     3241 aactacgact acctcatgta tgccgaccta gactttaaac atcctgaagt catccaaaac
     3301 atctatgact gggctgattg gttcatggaa acgactggtg tagctggttt ccgtttggat
     3361 gccgttaagc atattgactc tttctttatg cgcaacttca tccgcgatat gaaggaaaaa
     3421 tacggtgacg atttctatgt ttttggtgaa ttttggaacc cagacaagga agccaatctg
     3481 gactatctcg aaaaaacgga agaacacttt gaccttgtcg atgttcgtct ccaccagaat
     3541 ctctttgaag ccagtcaagc tggcgcaaac tatgaccttc gtggcatttt cacagatagc
     3601 ctggttgaac tcaagcctga caagtctgtg acttttgtcg acaaccacga tacccaacga
     3661 ggacaagccc ttgagtctac cgttgaagaa tggttcaagc cagcagccta tgccctcatt
     3721 ttgttacgcc aagacggcct tccatgtgtc ttttacggag actactatgg gatttcaggc
     3781 cagtatgctc aacaagattt caaagaaatc cttgaccgcc tcctagccat ccgaaaagat
     3841 ttggcctatg gagaacaaaa tgactacttt gaccatgcta actgtatcgg ttgggtacgt
     3901 tcaggtgctg aaaatcaatc cccaatcgca gtcttgattt caaatgacca agaaaacagc
     3961 aagtcaatgt ttgtcggtca agaatggact aatcaaacct ttgtagattt acttggtaac
     4021 caccaaggtc aagttacaat tgatgaggaa ggttatggac aattccctgt ctcagctaga
     4081 tccgtaagtg tctgggcagt caataccatc taatagctca taataaccaa gctaggtcca
     4141 agcggatttg gcttttttgt attcacaaaa agacctaccc aaatggatag atctttactt
     4201 gattacaatt tacctgctac tgcatccaac aattcttgga tcttagcttg gttgcttcct
     4261 cctgccatgg ccatgtctgg tttaccacca ccacgtccat cgatgattag tgctaattct
     4321 ttgacaaggt ttcctgcatg aaggtctttt gtcttgcttg ctacaaggac attgactttg
     4381 tcaccgatag cggcaactag gacaagaaga tcagagtagt ctttttgttt ccagttatct
     4441 gcaaaagtac gaagggcacc ggcatcggat acagacactt gactagcaat gtaacgatga
     4501 ccgttgactt ccttaacatc tttgaagata tcgcctgcgg ctgcagctgc ggctttttct
     4561 ttcaactcag cattttcttt ttgaagttga cgaagttgtt cttgaagtcc ttctaccttg
     4621 tgaggtactt ccttgacttg aggtgctttc aaggttgctg cgacagcttt aagagcatcc
     4681 tcttgttcac gataggcttc aaaggcttcc ttaccagtca ctgccaagat acggcgagtt
     4741 cctgaaccga ttccttcttc tttgacaatt ttgaagagac caatctcaga agtgttgcca
     4801 acatgagtac caccacaaag ttcaatagag tagtcaccga tagtcacgac acgaacttcc
     4861 ttgccgtatt tctcaccaaa gagggccata gctcccattt ctttagcagt gtcaatatcc
     4921 gtttcaactg tcttaacttc aagagcttcc cagatttttt cgttgacttg ctgttcaatc
     4981 gcacgcaatt cttcagcagt tacagcttgg aagtgggtaa agtcaaagcg aaggaattca
     5041 acttcgttaa gagatcctgc ctgtgttgcg tggtttccaa ggatattgtg aagggcagcg
     5101 tgaagcaaat gagtcgcagt gtggtttttc atgacacggt gacggcgatt gctatcaatt
     5161 gccaaggtat attcttggtt caaggcaagc ggtgcaagga cttcaactgt atgaagggct
     5221 tgaccatttg gggctttctg aacattggtc acagtagcca caaccttacc tgactcatcc
     5281 aagatttgtc cgtagtcagc tacctgtcca cccatttcag cataaaatga cgtttccgca
     5341 aagataagag aggcagttcc ttctgaaaca gcttctactt ctgcattgtc cgccacgata
     5401 gctaccaatt tagaagacaa ttggctagca ttgtagttga aggcactttc tacagtgatg
     5461 ttttgaagag tttcattttg catacccatt gagccaccct tgacagctga cgcacgcgcg
     5521 cgttcttgtt gttctttcat ggctgcttca aaaccttcac ggtctacagt cataccagct
     5581 tcttcagcga tttcttcagt caattcaact gggaacccat aagtatcata gagtttgaag
     5641 acatctgaac cagcgataac agattgacct ttttctttca agtctgctac aatgccttgg
     5701 gcaaagtgtt gacctgagtg aagggtacgg gcaaatgatt cttcttcgct cttaacgatt
     5761 ttctcaataa agtcacgttt ctcaagcact tctgggtagt agctttccat gatttttcca
     5821 acagttggaa cgagtttgta aaggaaaggc tcgttgatac ccaatttttg accatgcata
     5881 gaagcacgac ggagaagacg acgaaggaca taaccacgac cctcatttcc tggaagggca
     5941 ccatcaccga tggcaaatga aagtgaacgg atgtggtcag cgatgacctt gaagctcatg
     6001 ttgtcgccat cttggtcata aaccttacca gacaatttct cgacttcacg gataatcggc
     6061 atgaagaggt ccgtttcaaa gttggtctta gccccttgga taacggccac caaacgctcc
     6121 aaaccagcgc ccgtatcaat gttcttatgt ggcaattcct tgtattcgct acgaggaaca
     6181 gcagggtctg cgttaaattg tgacaaaacg atgttccaga tttcaatata acggtcgttt
     6241 tcaatatctt ctgcaagcag gcgaagaccg atattttctg ggtcaaaggc ttccccacgg
     6301 tcaaagaaga tttctgtatc tggtccagaa ggtcccgcac cgatttccca gaagttgtcc
     6361 tcaattggaa tcaagtgact tggatccact cccacttcaa tccagcggtt gtaagaatct
     6421 ttatcgtctg gatagtaggt catgtaaagt ttttcagcag ggaaatcaaa ccattcaggg
     6481 cttgtcaaaa gctcataagc ccaagtgata gcttcgtcac ggaagtaatc cccgatagag
     6541 aagttcccca acatttcaaa catggtatgg tgacgcgcag tcttccctac gttttcgatg
     6601 tcgttggtac ggatagcctt ttgggcattg gtaatacgtg gattttcagg gataatggtc
     6661 ccgtcaaagt atttcttaag ggttgctacc ccagagttga tccacaaaag agttgggtca
     6721 tttacaggaa ccaaacttac tgatggttct actgagtgac ctttggtcgc ccagaaatca
     6781 agccacattt ggcgtacttg tgcactagat agttgtttca tattgtctcc ttattcactt
     6841 gtttaatgtg attggctttc cagtatttcc acatagtcaa tcgcgacaca gagggaaatg
     6901 actaggtctg cataagcgtc ttcaagaacc gttacggtat aggtagaggt cagatggaag
     6961 agttccttct taatttccgc aatcaactga tcgcgatcat ccagcaattt gaaattcaaa
     7021 tcccagatat tgccctcgat acgaagacct agattatcaa actcatactt atctcgccaa
     7081 aaggtcaact tcttacgaat gacaaaactc gagccatccc gaagctgaat ctcaaaacga
     7141 ggaagcaagg tcaagatttc tttactgatc tgactgactt gttcaccagc cgcatcatag
     7201 atggtaaaag ttttgggaat cttaaaaaat gatccctcca cctgataggc aatttctccc
     7261 ctgtcatcct tgatagcgaa gcgttcgcct ccaagacgaa acttttgttt gacaagaaat
     7321 gttttcatca acacctccaa aaatcaaaag acaagctcat atcacgaagg gcgaaaaacc
     7381 gcggtaccac cttcattcaa tgaacttgtc attctcttgt tcttatgcaa ttgtatgatt
     7441 gagtagcatg acttcctagc ttagatggct cgcagcaccg ccatttctct ggactaagac
     7501 aagtgaaaat caattctcaa ctttcttatt ataacgtttt tttaagcttg cgtcaactgg
     7561 aaatgatctc cgttgaatta gaccaattcc ctacatctct gattactttt tcaggatata
     7621 ttttttctta ctgccgtttt tctttttatc ccaaattttc atattactaa acacagctac
     7681 tagaatattt ccaaatataa aggtgcctat cacccaatat atggactcag ttgttaggta
     7741 ttgtcgatcc aagccatcct ttaaatggaa tagtataaca gtttggttaa caatcataaa
     7801 ggttggccag aaactttttt tgaaaaaagt agacattttc attatttgtt gccgctttct
     7861 gtaaggttaa tactcaataa aaatcaaaaa gcaaactagg aagctagcct caagctgtac
     7921 ttgagtacgg caaggcaacg ctgacgtggt ttgaagagta taggctaagt atactactag
     7981 gcaagcaaat aagcaaataa acaactagaa tagaaaaaga tagggctcta aaaactgact
     8041 tctattcctt aaaaacgaac cagcttgact gattcgtctt cttacgttta tctcctactt
     8101 ccgatacatt ttaaactgta ggaagaggtc gctatatttc cctgtccatt tatggtcaaa
     8161 tttctcataa acttctaggt gtttcatggt ttcaacatcg ggatagaagg ccttatcttc
     8221 ctttgtttcc tctgggagca atttcttcgc tggtaggttt ggtgttgaat agccgacata
     8281 ctccgcattt tggagagcat tttcaggttt caacataaag ttgataaagg cataggctga
     8341 gttttggttt ttaactgttt tgggaatgac catattgtca aaccaaagat tgctggcctc
     8401 tgtcggtacc acataacgta gattttcatt tttttctaac atttggctgg cttcaccaga
     8461 gaaggtcacg ccgattgcaa cattattctg aatcatatag cccttcatct cgtccgcaac
     8521 gatagccttg atatttggag tcagtttgta gagcttatcc actgtctctt ccaactgctg
     8581 caattccttg gagttgaggc tgtagccgag ggaattgagc cccagaccca gcacctcacg
     8641 cgccccatca aagagcatga tagaattctt atactccggc ttccaaaggt catcccaatg
     8701 ctcaggcgct tcatctacca tggtttcgtt gtagacaatt cctaaggttc cccagaagta
     8761 agggatggag aatttattac ctgggtcaaa ggactggttg agaaactctg gtccgatatt
     8821 ttcgattcct tcaatttttg aataatcaag cggaaccaag aggtcttcgt ccttcatctt
     8881 gttaatcatg tattcacttg gaatggcaat atcgtaggtc gttccaccct gctttatctt
     8941 agtgtacatg gcttcgttgg agtcaaaagt ctcgtactga acttgaattc ctgtttcttc
     9001 tgtaaactga gtcaagagtt caggatcgat atagtctccc cagttataga taaccaattt
     9061 ttgactatct cgactattga ttttactatc taaatgagtc gcaattcccc acaagacaag
     9121 gataatcgct gcaattcctg ctaaaaatga atagattttt ttcatgcttg ctcctccttc
     9181 tcacgagaga taaagtaata acctacaact aggataatac taaagagaaa gactagagca
     9241 gacagggcat tgatttctaa ggaaatccct ttccgtgcac gagagtaaat ctcgactgac
     9301 agggttgaaa agccatttcc tgttacaaag aaggtcacgg caaaatcatc cagcgaatag
     9361 gtgaaggcca tgaagtaacc tgcaatgata gacggagtca ggtaaggaag catgatttcc
     9421 ttaaacatct gaaattgact agctcccaag tcataggccg catgaatcat gtcgccattc
     9481 atttccttga gtcgaggcaa aaccatcaag accacgatag gaatggagaa ggccacgtga
     9541 ctagatagaa cggtcaaaaa gccaagtgaa aacttgagtt gggtaaagag aatcaagaag
     9601 ctagcaccaa tcataacgtc aggcgcaacc atgaggatat tattgagtga tagaaaggct
     9661 tcttggtatt tcttacgaga ctggtagatg taaatggcac caaaagtccc gataatggtc
     9721 gctatcaagg ctgataggaa ggccaagaaa aaggtctgag ccaaaatcag catgagtctc
     9781 ccatctccaa acatggtttc aaagtgagtc cagctaaaac ctgtaaagct attcatatca
     9841 tcaccagcat taaaggcata gccaatcaag taaaagatag gcaggtagag gaccagaaag
     9901 accagtccca gataaaggtt ggcaaatttt ttcatcgttc tctcctttcc ttagtcaccc
     9961 acatggtgat gaacatggtc aggatgagaa tcacaccgat ggttgaaccc ataccatagt
    10021 tgtcattggt tagaaaattc tgctcaatag ccgtccccaa ggtgataacg cggttcccac
    10081 caatcaaacg ggtcagcatg aagagactca aacttgggat aaagaccgac tgaaccccac
    10141 ttcgcacacc gttcatagat agagggaaga tgacatgacg gaaggtctcc cacttagttg
    10201 caccaaggtc atagctggca ttgatgagat tattatccat atcgtctaag acattgaaaa
    10261 tcggcaaaat cataaagggg agctcgatgt agcttgcgac aaagataaag gaaaaatcgg
    10321 taaaaagcaa ctgttgtgaa ccaattccga taaattccaa gaattggtta atagagccat
    10381 tttgaccaaa aatcccgata aaagcatagg ctttaaggag caaattgatc caggtaggaa
    10441 ggataatcag catgagccag agttgacggt gcttgagacg ggtcaaaaag agggctgttg
    10501 gatagctgat aagcaaggtc acaaaggtca caatccctgc ataaagcact gagttgaaac
    10561 tcattttgag gtaggtcaag ttttgtgacg caaagtaaga tttataattt tctaaactaa
    10621 actggccttc aatgttgaaa aaggattgtc cgaaaatcaa gaccaagggt gccaatacaa
    10681 agagggcaat ccaaagcatg tagggcacta caaagagttt agagcttgtt ttcttcatct
    10741 ctttcctcct cgatcgcatt gatcagacct gcttcttgct cttcgatttc cacgtattct
    10801 tcgatacgag catcgaactc ttcttcggtt tcattgagac gcatgatgtg gatgtcttct
    10861 ggttcaaagt ccagaccgat ttcctcaccc acgatggcct tacgggttga gtggatcatc
    10921 cattcatttc caagttcgtc ataggcgata atttcataat gaactccacg gaagagctgg
    10981 gtgtcgacct taacttggag tttgccttct tcaggaaggg taatgcgcaa gtcctctgga
    11041 cgaataacga cctcaacagg ttcatttggc ttcatcccac catcaaccgc ttcaaagcgt
    11101 ttgccgttaa attcgaccaa gtagtcctca atcatggtac ctggcaagat gtttgactcc
    11161 ccgataaaag tggcaacaaa gtggttgatt ggctcatcgt agatgtccac aggggttcca
    11221 gactggacaa tctcgccatc attcataacg aaaatccagt cactcatggc aagagcttct
    11281 tcctgatcgt gagtgacaaa gacaaaggta atgcccaatc gttgttgtaa ttcacgcaat
    11341 tcgtactgca tgtctgttct caatttcaag tccagcgctg ataaaggctc gtccaacaag
    11401 accacacggg gttggttgat gatagcacgg gcgatggcca cacgctgacg ttgtcctcca
    11461 gaaagtttgc ggatggaacg tttttcataa ccttccaact gaaccatctt gagaacttcc
    11521 gctacacgct gctcaatttc tttcttatca attttacgca agcgaagtgg aaaggcaaca
    11581 ttttcaaaca cattcatatg tgggaacaag gcataggatt ggaagacggt atgtacgtcg
    11641 cgcttgttgg ttggaatatc attgatacga acaccgtcta gcatgatatc tcctgtcgtc
    11701 gcatccagta aacctgcaat aatgtttagg atagttgatt tccccgaacc agatgcacct
    11761 agaagggtgt agaatttccc ttcttccaac tcaaagttga tgtctttgag aaccttggtg
    11821 ttgctgtctt caaaaacttt agagacgttt ttgaattcga taattggttt tttcaattgg
    11881 cataaattcc ttctttttca tagattaacc gatcggggct ctgtcaggtc cccactacct
    11941 cttgcaggga gtaaaaccac ctgcatacat cttcgctacc gataggcttt cacccaagat
    12001 ccggacttct ctttcaagcg taatacctga gtgttccttg actttttcga taaccgattg
    12061 gatcaagtcc tcgtagtctt tggccgttcc atctgcgaca ttgatcataa atcctgcatg
    12121 cttttctgac acttctacgc caccgatacg atagcctttc aagccagctt ctgaaattaa
    12181 ctgacctgca aaatgcccga ctggacgctt aaagaccgag ccacaagatg ggtattccaa
    12241 aggttgcttg agttcacgta ggtgcgtcaa gcggtccatt tcctgcttga taacctgatg
    12301 ggttcctgga gctagggcaa atttaactga caagacaact gcaccagact cctgaatagc
    12361 tgaatggcgg taaccaaaag ccaagtcttt agcagacagg gtttcgattt ctccatcctt
    12421 ggtcaagacc ttacaagact gcaagatgtg agcaatctcg ccaccatagg cacccgcatt
    12481 cataaagaca gcaccgccaa cgcttcctgg aataccacaa gcaaactcaa agccagttaa
    12541 actatgacgg agggcaatgc gagttgtttc aatcaagtta gccccagctt ctgcttcaat
    12601 ggtatagcca tcaacagaaa cgttattgag cttgtcacac aagatgacaa atccacgaat
    12661 cccaccatca cgaacgatga tattgcttgc attgccaaga accatccaag ggatattttc
    12721 ttggttggca aatttcacaa cgcgagccaa ctcaaaacga tttcgtggaa agaccaaata
    12781 atcagcctct ccacctactt ttgtataact atagctatgc aagggttcct taaaacggat
    12841 atcaattcct tctaagattt caagcatttt ttctcttaca gacatgtcac tcttcctttt
    12901 acaaaattca ttccattata ccatttttag agacatttga cgaccataaa aataccttgt
    12961 ttggattttg cataagaaaa agaggttccc ccctttttat gattttttac aaaagatttc
    13021 cttggttcca taggcgacca gaacgagctc cagtgctaga atcacttcaa ccaagactgg
    13081 atttgtcaac cagcctactt ggaaaagaga tggtgccaga tcaaagaagg catgcaagcc
    13141 ataggctgct aggagataaa tccatttctt ctggcgaaca gcttggtaaa cccaaactgt
    13201 caaaagtaat tggaaaccaa gcgccaagat tcgctcaaaa ccaagcaaat aaatctgcca
    13261 gaccgaaagt gactgaatgg tttttaacat attttcagac agtaattgca taacctgtgc
    13321 tgtggattct gagtttgaac tgccgaaaga acgatgtaaa gattgagtaa actagtaagg
    13381 cctagaaaaa tcaactccaa gccaccatgc cctaggccat aggccaaggc atctgccttt
    13441 tccaaacttc tctttttctc caaccatttg aagaaaacaa gacgagccgt ttcctcaaaa
    13501 aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg caagagggca
    13561 atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc caaaatctgc
    13621 gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat ctgatatttc
    13681 tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat ggtaataatg
    13741 atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt catctcgtca
    13801 acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg gtccaactgg
    13861 tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac atgtccaccg
    13921 aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac cccatggaaa
    13981 atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact atattccggt
    14041 tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat catacgcaca
    14101 tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc cccatcataa
    14161 taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg gcgaaaaatg
    14221 acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg tgacacttcc
    14281 acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc caagacaatc
    14341 aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc tagcaattct
    14401 cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt attgtattga
    14461 aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg ttattctata
    14521 aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa acgctctaga
    14581 cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg tctggaatga
    14641 agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc gagtctgaac
    14701 gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac tttcactgca
    14761 gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac ctctatgcca
    14821 agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta gaaatcgagg
    14881 ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat gaaaccttga
    14941 ttggacgaga aaactacctc ttcaactact atgacaatca agaaggatta gaagacctaa
    15001 gacagtccat tcacaaactc ctatttgagc aagctctcta ctgcaaggct aaccaactag
    15061 tactgacttc tggaacccaa caagccttgt ttatcctctc tcaaatatcc tttcctagac
    15121 aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc ctcttgattg
    15181 cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac ttggaggagc
    15241 tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattcct agatttcact
    15301 atcctctggg acattcctat tctgagcaag acaaactatc tattcttaac ttagctgcca
    15361 agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc aagaagggcc
    15421 aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc ttctcgacca
    15481 gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc aaagaagcat
    15541 ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa aaggccctgt
    15601 cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg accaatcatg
    15661 aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc cttcctcatt
    15721 atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc gccagtctca
    15781 aacacagtca actgggcttg gacttctttg aagaggccta tttaagcacc tgtccttatc
    15841 aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta aaagcagaat
    15901 tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac ttgctgcttt
    15961 ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct tgtctaccac
    16021 ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc cgtccttcat
    16081 cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac taagtgcaac
    16141 aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga ctgcttcacc
    16201 catattagtt agggaagtta attgaacttt tggcaattgt tccttgacca ttgattctgg
    16261 aacagtccct ttttgggctg caatattagc actttttagg ttagttaaat ccttgtattt
    16321 ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg ggattgaaaa
    16381 atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta ggtcagcctt
    16441 accagtttga agactggtca aaacattatc aaaactcatg cttgagattt ccaacttaac
    16501 cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta cctggtcctt
    16561 tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg ccacaactaa
    16621 tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac ctgactggca
    16681 agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt tttttgattt
    16741 cataaataaa ca
//
LOCUS       DAVKAU010000041        16532 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVKAU010000041 DAVKAU010000000
VERSION     DAVKAU010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.041"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(197..655)
                     /locus_tag="VWX48_001530"
     CDS             complement(197..655)
                     /locus_tag="VWX48_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU9172132.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(652..1092)
                     /locus_tag="VWX48_001531"
     CDS             complement(652..1092)
                     /locus_tag="VWX48_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9172133.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1448..3397
                     /gene="mutL"
                     /locus_tag="VWX48_001532"
     CDS             1448..3397
                     /gene="mutL"
                     /locus_tag="VWX48_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU9172134.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3722..4189)
                     /locus_tag="VWX48_001533"
     CDS             complement(3722..4189)
                     /locus_tag="VWX48_001533"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU9172135.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(4190..5395)
                     /locus_tag="VWX48_001534"
     CDS             complement(4190..5395)
                     /locus_tag="VWX48_001534"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU9172136.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5415..6050)
                     /gene="ribE"
                     /locus_tag="VWX48_001535"
     CDS             complement(5415..6050)
                     /gene="ribE"
                     /locus_tag="VWX48_001535"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU9172137.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(6035..7135)
                     /gene="ribD"
                     /locus_tag="VWX48_001536"
     CDS             complement(6035..7135)
                     /gene="ribD"
                     /locus_tag="VWX48_001536"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU9172138.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7269..7383)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7540..8133
                     /gene="ruvA"
                     /locus_tag="VWX48_001537"
     CDS             7540..8133
                     /gene="ruvA"
                     /locus_tag="VWX48_001537"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU9172139.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            8143..8706
                     /locus_tag="VWX48_001538"
     CDS             8143..8706
                     /locus_tag="VWX48_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU9172140.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8703..9380
                     /locus_tag="VWX48_001539"
     CDS             8703..9380
                     /locus_tag="VWX48_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9172141.1"
                     /translation="MMSNKNKGILIFVILYTVLFVFDGVKLLASLMPFAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9535..10566)
                     /locus_tag="VWX48_001540"
     CDS             complement(9535..10566)
                     /locus_tag="VWX48_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU9172142.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKHLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(10821..11504)
                     /locus_tag="VWX48_001541"
     CDS             complement(10821..11504)
                     /locus_tag="VWX48_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU9172143.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11516..12460)
                     /locus_tag="VWX48_001542"
     CDS             complement(11516..12460)
                     /locus_tag="VWX48_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9172144.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12592..15423
                     /gene="uvrA"
                     /locus_tag="VWX48_001543"
     CDS             12592..15423
                     /gene="uvrA"
                     /locus_tag="VWX48_001543"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU9172145.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHG"
     gene            15416..16477
                     /locus_tag="VWX48_001544"
     CDS             15416..16477
                     /locus_tag="VWX48_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9172146.1"
                     /translation="MDKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         4650 a         3288 c         3549 g         5045 t
ORIGIN      
        1 aagatctgaa ataactgtta tgatatagcg gattgaaact agaatagtac acctctgctt
       61 ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttatcctgt tcttatttca
      121 tttcactata gtaaggtgca gcaggataaa gaaaaaccga gaagtttctt tctcggattt
      181 gcttattatg aggttcctat tttctatgct ccaagagttg attgatgtga tctacttttt
      241 tagcctctct tttatagaga atagcccaga tgatgagata gacaatcgca aactcgataa
      301 tgagctggag gtagaaaatc cagtggaaag ggaaccaacc agcaagagtt gctagtggga
      361 caaagccagc cagcataagg aagaaatgag tcagagtggc acgaagcatg ctccagtcac
      421 ggctgaataa gcggttgcca aagttgaaga gcataccgat ggctgcccag ataagtgtgc
      481 agtagagcaa gaccagggca ccgtgaacct gatgctgatc catcacttgg ccgatgagag
      541 agtagggatt tagtggtgcg taggtatttg gtgcataaat gagtgaaaag aggatggaga
      601 ggatgaggcc gataagaaca ccggcagctg catcgtgaaa tacttgtttt ttcatagttc
      661 taatttctcc ttgatggttt ttagataacg gcgtgaagag taggtgaagc tttcgttttt
      721 caagaaaatt tctaccagac cgtttggcgt gagcttgagg tgagagatgg aatcgatatt
      781 gatgatttct gattgggaaa tttggataaa attgcttggc aagagtttaa gaacctgata
      841 gagtcgcaaa tcaatgctgt aggtctgact cgcggtttct gctagaacct tccgattctc
      901 gatatagaag cgctgaatct tgccaatctc aactagatag acctgatcat cgatttttcc
      961 tttgattttt tctctttggt ccagattttc tgcgaactcg atgactttct ggactttttc
     1021 ggtttcttga ggtgcttgga caatcagctt ttcctcctcg taagtctcac taatctgtag
     1081 ttctactttc atagttttct ctccttgttt ttcatacaaa attaatctca cttcttgtac
     1141 acctttatta atactcttca aaaatctctt caaaccacgt cagcgtcgtc ttgccgtagg
     1201 atagttgttg actttgtcag ttttatctac aacctcaaaa cagtgttttg agctgtctgc
     1261 gcctagcttt ctagtttgct ctttgatttt tattgagtat accactattt tactccctct
     1321 ggcaagggac tttgtctatg tggagggatt gggctcctat gtggtggagc ttttctgttc
     1381 tttctgaaat atggtataat agcactaatt aatttctagg aaaatagata cagaaagggg
     1441 ctgaaagatg tctcatatta ttgaattgcc agagatgctg gcaaaccaaa tcgcagctgg
     1501 ggaggtcatt gaacgtcctg ccagtgtggt taaagagttg gtagaaaatg ccattgacgc
     1561 gggctctagt cagattatca ttgagattga ggaagctggt ctcaagaagg ttcaaatcac
     1621 ggataacggt catggaattg cccacgatga ggtggagttg gccctgcgtc gccatgcgac
     1681 cagtaagata aaaaatcaag cagatctctt tcggattcgg acgcttggtt ttcgtggtga
     1741 agccttgcct tctattgcgt ctgttagtgt cttgactctg ttaacggcgg tggatggtgc
     1801 tagtcatgga accaagttag tcgcgcgtgg gggtgaagtt gaggaagtca tcccagcgac
     1861 tagtcctgtg ggaaccaagg tttgtgtgga ggatctcttt ttcaacacgc ctgcccgtct
     1921 caagtatatg aagagccagc aagcggagtt gtctcatatc attgatattg tcaaccgtct
     1981 gggcttggcc catcctgaga tttcttttag cttgattagt gatggcaagg aaatgacgcg
     2041 gacagcaggg actggtcaat tgcgccaagc aatcgcaggg atttacggtt tggtcagtgc
     2101 caagaagatg attgaaattg agaactctga cctagatttc gaaatttcag gttttgtgtc
     2161 tttacctgag ttgactcggg ctaaccgcaa ttatatcagc ctcttcatca atggccgtta
     2221 tatcaagaac ttcctgctca atcgtgctat tttggatggt ttcggaagca agcttatggt
     2281 tggacgtttt ccactggctg tcattcacat ccatatcgac ccttatctag cggatgtcaa
     2341 tgtgcatcca actaagcaag aggtgcggat ttccaaggaa aaagaactga tgaccctggt
     2401 ttcagaagct attgcaaata gtctcaagga acaaaccttg attccagatg ccttggaaaa
     2461 tcttgccaaa tcgaccgtgc gcaatcgtga gaaggtggag caaactattc tcccactcaa
     2521 agaaaatacg ctctactatg agaaaactga gccgtcaaga cctagtcaaa ctgaagtagc
     2581 tgattatcag gtagaattga ctgatgaagg gcaggatttg accctgtttg ccaaggaaac
     2641 cttggaccga ttgaccaagc cagcaaaact gcattttgca gagagaaagc ctgctaacta
     2701 cgaccagcta gaccatccag agttagatct tgctagcatc gataaggctt atgacaaact
     2761 ggagcgagaa gaagcatcca gcttcccaga gttggagttt ttcggacaaa tgcacgggac
     2821 ttatctcttt gcccaagggc gagatggact ttacatcata gatcagcacg ctgctcagga
     2881 acgggtcaag tacgaggagt accgtgaaag cattggcaat gttgaccaga gccagcagca
     2941 actcctagtg ccctatatct ttgaatttcc tgcggatgat gccctgcgtc tcaaggaaag
     3001 aatgcctctc ttagaggaag tgggcgtctt tctagcagag tacggagaaa atcaatttat
     3061 tctacgtgaa catcctattt ggatggcaga agaagagatt gaatcaggca tctatgagat
     3121 gtgcgacatg ctccttttga ccaaggaagt ttctatcaag aaataccgag cagagctggc
     3181 tatcatgatg tcttgcaagc gatctatcaa ggccaatcat cgtattgatg atcattcagc
     3241 tagacaactc ctctatcagc tttctcaatg tgacaatccc tataactgtc ctcacggacg
     3301 tcctgttttg gtgcatttta ccaagtcgga tatggaaaag atgttccgac gtattcagga
     3361 aaatcacacc agtctccgtg agttggggaa atattaaaag tataaaaaag tctgggaaaa
     3421 attttcaaaa tcagaaaaac gcataaaatc aggtgttcaa aaaccttgat tttatgcgtt
     3481 ttatcatgga aatagttact tcatgttttc ctaattcttt tcgaaactct ttttaaacca
     3541 cgtcagtttt atcagtaatc tcaaaacagt gttttgagct aattttgcca gttttgtctg
     3601 taacatcgaa gttgtgtttg accactctgc gactggtttc ctagtttgct ctatgatttt
     3661 cacagagtat taaattgcga ttttgccaag tttctttatt cgtctaaaag tagagtctgt
     3721 tctatgcgtc taatgtacga attaggttga ccatttcaat agctccttgt gcacactcag
     3781 aacccttatt tcctgcttta gtaccagctc gttctatggc ttgttcaatt gtatctgtcg
     3841 ttagcacacc aaacataaca ggaatttcgc tatttaaact gatttgggcg attcctttag
     3901 atacctcgct acatacataa tcataatgac ttgtattccc tctaatgaca gctcccaagc
     3961 agataattgc atcatatttt ttactttttg ccatttttga tgcaatcagt ggtatttcaa
     4021 aagctcctgg aacccaggct acctcgatat ctttctcgtt tacattctct cttttgagat
     4081 tatctagtgc tccagataat aattttgaag ttataaattc attaaatctc gctacaacaa
     4141 tacctatttt aatattgttt gctactaaat taccttcata agtgttcatt tatttttcct
     4201 ccatatttaa aatgtgaccc attcgatttt tctttgtttc taaataaaaa ctatcgtaag
     4261 gattggcttc tatttcgatt gatattctac tggaaatggt aattccatat ttttctaact
     4321 gttcaacctt gtcaggatta tttgtcagta aatgaagtga ctgaagtccc agatctttaa
     4381 gcatttgtgc tccaatatga tattctctta aatcaccttc aaagcctaat gcaagattgg
     4441 catcaagcgt atccatgcct tgatcttgta aatgataggc ttttaattta ttgataagtc
     4501 caattcctcg tccctcctgt cgcaagtaaa gtaagacacc cgaaccattc tcaacaatca
     4561 ttttcatagc tttatcgaat tgctgtccac aatcgcaacg taaagagcct aaaacatctc
     4621 ctgttaaaca ttcggagtgg acccgacata atacattggc ttcatcctct atgtttccca
     4681 taataagagc aagatgatgt tccccattta gtttatctat atagctaatt gctttgaaat
     4741 taccgtatct agtaggcata ttgacagttg aaactcgttc taccagctga tcatatactt
     4801 ttctatattc ttgtaattct ttgatggtaa ttagtggaat gttgtgtttc ttcgagaact
     4861 gaattaaatc atctgttctc atcattttgc catcatgatt cattatttca caacataggc
     4921 cacactcttt tagtccagct aattttaata aatcaacagt tgcttctgtg tgtccatttc
     4981 tttctagaac accacctttt tttgcaatta aaggaaacat gtgtcctggc ctgcgaaaat
     5041 cagagggtgt tatatcttca gctacacaca tacgtgcggt cagtcctctt tcctcggcag
     5101 aaatacctgt ggtcgtttct ttataatcaa ttgaaactgt aaaagcagtc ttatgattat
     5161 ctgtattgtt ttcaaccata ggtgaaagca ttaattgatt agctaaactt tcgctcatag
     5221 gcatacaaat taatcctttg gcataagtag ccataaaatt aacattttct gttgtagctg
     5281 cttgtgcaga acaaattaag tctccttcat tttctctatc cttgtcgtct ataacaagaa
     5341 caagtcgtcc cttctgcaat gcttctaatg cttcttgtat ttttcgatat tccattgact
     5401 gattatcctt tctgctaaaa tccattttga tataatagtt ccttcgatat ttctgatttt
     5461 ggagagttat ccatcagttt ttgcacatat ttacctaaga tatcattttc aagatttact
     5521 gtactcccga cttgtttact cttaagaatg gtttgtttca aggtatgagg gataacagat
     5581 actgaaaagt ttactttgga gactttagcg acagtcagac taatgccgtc aattgtaata
     5641 gatccttttt caactattaa atctaaaatt tctttttgtg tgttgatttg ataccataca
     5701 gcattatcat ctttttttat tgacgagatt tttcctgtac catcaatgtg tcctgtaacg
     5761 acgtgacccc caagtcgacc gttgacagat aaggctcttt ctagattcac ctcacttcca
     5821 tgttttaata gagtaagagc tgttcgactc catgtttcat tcattacatc aactgtaaag
     5881 gattgatgat tgaaatgagt aactgtaaga cagataccat ttactgctat actatcgcct
     5941 aaatggatat ccgttaatat ttttgaggct ttaattgata gtttacaatt acgagagtct
     6001 ttctgtattc tttcaacttt tccgatttct tcaattattc ctgtgaacat ggataaatca
     6061 cttcactttc tatgagatag tcatttccta tttgagaaaa agcataaggt ttcaatctaa
     6121 tagcgtcatt tggcaaagaa atgccttcac ctccgacagg aaacttggca ctgcctccaa
     6181 aaatttttgg tgcaatatat attttcagct catcaacaat ttgttgttcc aaagcactcc
     6241 aattcattag actgcccccc tctagaacta ggctatcaat ctgcatgttt cctagatgtt
     6301 gcattaaact cgataagtct atatgattgc cttttttctt tatggaaagt atttcacagc
     6361 catgattttg atatagcttc attttatttt tgtcttcaga ggaagtggca atgtaagttt
     6421 taatatcatt tgctgttttt acgattttag aggtaagagg agttcgtaaa tgtgtatcgc
     6481 atatgatacg gataggattt ttcccttcct ccaatctaca tgtcagcaaa ggatcgtctt
     6541 gaataacagt attgactccc accataattg cactaacata gtgtcgtaac tgatgcacat
     6601 gctttcttgc ttcttcttca gtaatccatt tggattgatt tgttttagtg gctatttttc
     6661 catccattga cattgcatat ttcataaaaa catagggtac atgctgggta atatactttc
     6721 taaaactttt tattaagtta agacactcat tttctaaaat tccaacagta acttgaagat
     6781 tattttcctc aagtatcttt actccttttc cagatacaat aggattacag tctaggcttc
     6841 caatgactac tcttgtaata ccactatcga ttatagcatc tatacaggga ggtgttttcc
     6901 cgaagtgaca acagggttca agtgttacat aaagcgtcgc tccgacaggg gattttctac
     6961 agtttttaag agcatttctc tcagcatgtg ggccaccaaa aaactcatga taaccttgtc
     7021 cgataatgtg attatctttt acaataattg cgccaaccat aggattggga ttgacgtaac
     7081 cagccccttt ttgtgccagt tttattgcta atttcatata ttttgaatcg ctcatctcac
     7141 tacctccaaa aaaatatacc ttgaataggg gactactcaa ggcatacaaa agaaaactta
     7201 tgcgattaac aaaaatgctc tgaaatgaca agtaatcatt tcagagcacg caaaaagcac
     7261 aaatatactt ttatcttctt tcatccagac tatactgtcg gctttggaat ttcaccaaat
     7321 catgcctttc ggctcgtggg ctataccacc ggtagggaat tgcaccctgc cctgaagata
     7381 gttattcaat tacagatgat tatagtactt aattttgaat atgtcaacag ataaatacag
     7441 attgtttttg atatactgta tttgtgataa tcgattctcg ctcctcggat aaagaaaata
     7501 tgatatacta gataaacgaa ataagagaga aggaacacta tgtacgcata tttaaaagga
     7561 atcattacca aaattactgc caaatacatt gttcttgaaa ccaatggtat tggttatatc
     7621 ctgcatgtgg ccaatcctta tgcctattca ggtcaggtta atcaggagga tcagatttat
     7681 gtgcatcagg ttgtgcgtga ggacgcccat ttgctttatg gatttcgctc agaggatgag
     7741 aaaaagctct ttcttagtct gatttcggtc tctgggattg gtcctgtatc agctcttgct
     7801 attatcgctg ctgatgacaa tgctggcttg gttcaagcca ttgaaaccaa gaacatcacc
     7861 tacttgacca agtttcctaa aattggcaag aaaacagccc agcagatggt gctggacttg
     7921 gaaggcaagg tagtagttgc aggagatgac cttcctgcca aggtcgcagt gcaagcaagt
     7981 gctgaaaacc aagaattgga agaagctatg gaagccatgt tggctctggg ctacaaggca
     8041 acagagctca agaaaatcaa gaaattcttt gaaggaacga cagatacagc tgagaactat
     8101 atcaagtcgg cccttaaaat gttggtcaaa taggagcaga gaatgacaaa acgttgttcg
     8161 tgggtcaaga tgaccaaccc gctctacatc gcctatcatg atgaggagtg gggtcagccc
     8221 ctccatgatg accaagcatt gtttgagttg ttgtgtatgg aaacctatca ggcaggcctg
     8281 tcttgggaaa cggtactcaa caaacgccaa gctttccgag aagcctttca tagctatcaa
     8341 attcactcag tcgcagagat gactgacact gaattggaag ccatgctgga gaatccagct
     8401 atcattcgaa atagagccaa gatttttgct acacgcgcta acgcccaagc ctttctacag
     8461 ttacaggcag agtacggctc ttttgatgcc tatctttggt cttttgttga ggggaaaact
     8521 gtcgttaacg atgttcctga ttatcgccaa gccccagcta aaacaccctt atctgagaaa
     8581 ttagccaaag atctcaaaaa acgaggcttc aagttcacag gcccagtcgc cgtattgtct
     8641 tttctacagg ctgcagggct agttgatgac cacgagaatg attgtgagtg gaaaggtctt
     8701 aaatgatgtc taacaaaaat aagggaattc tgatttttgt gattctctat acagtcctct
     8761 ttgtgtttga tggcgttaaa ttgctggctt ctttaatgcc atttgccatt gcaaattatc
     8821 ttgtttatgt agttttagct ttatatggct ccttcttgtt caaggataga ttgatccaac
     8881 aatggaagga gattagaaag actaaaagaa aattcttctt tggagtctta acaggatggc
     8941 tctttctcat tctgatgact gttgtctttg aatttgtatc agagatgttg aagcagtttg
     9001 tgggactaga tggacaaggt ctaaatcagt ctaatattca aagtaccttt caagaacaac
     9061 cactactgat agctgttttt gcttgtgtca ttggacctct ggtagaagaa ttatttttcc
     9121 gtcaggtctt attgcattac ttgcaggaac ggttgtcagg tttactaagc attattctgg
     9181 taggacttgt ttttgctctg actcatatgc acagtttggc tctatcagag tggattggtg
     9241 cagttggtta cttaggtgga ggccttgcct tttctattat ttatgtgaaa gaaaaagaga
     9301 atatctacta tcccctactt gttcacatgt taagcaacag cctctcctta atcattttag
     9361 ctatcagtat agtaaaatga aataagaaca ggacaaatcg atcaggacag tcaaatcgat
     9421 ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatttgc tgtaatatgt
     9481 gatgaaaatg ccagtaataa taccgagaaa aaagctgaga aacttttccc agctttattt
     9541 gttatagtca aagcgaatga cttgttcctg tgcatctaca tgagcatgaa ccccaaaggg
     9601 tacaattgct cttggagttg cgtggccgac attcagatta tagacaatcg ggatattgct
     9661 gtcaatgata tccaatagtg cctctttata gtcgtcatgg aaagtttcat ccataggttt
     9721 tccgaccaag agtccattga tgaccgcgaa tatgccagtg tcctttaaag ttagcaacat
     9781 ctttttgaag tcttctggtt taggcttttc ttcgcttgtt tcgagcaaga ggattttccc
     9841 ttcccagtct gacaagtcag ggaaaagttt gtatttttgg cagagttccg tgctatctgc
     9901 gtatcgagag ttgtcaaaga tatcgtagag ggattcgagg caaccaccga ggattttccc
     9961 ctcgaactga gcacttcctt gcaacaagtc aaaacctgta tttgtatgac tgacacgagg
    10021 tgttcccagg gctgtgggac taaaatcagt tcgttcctca taccaaacgt cactagggcg
    10081 gatttctgaa attcttcccg tcttaatcaa ttctttaaag tagtgaaggc tataggctag
    10141 catttctttg tctaattcac aaatgtctgc taaaaaggat tgaccataaa aagtcttgat
    10201 tcctaattta tgcaacatga ggtggttcat ggttgtatcc gagaagccaa gaaaaatttt
    10261 ttgcttgata accttttgga gttggtcatt ttcaaaaaga taaggtagca agcgataggt
    10321 atcgtctcca ccgatggcac ataggatcat gtcgatgcta tcatcagaaa aggcatgaat
    10381 caaatcctct gcacgagctt caggatggtc cttgataaag tctaatcctt ttaacgaatg
    10441 ggacaaaaag atgggattga gtcccagatg cttgagacgt tggataccca agtccacttc
    10501 gtgtttgaca aaatcctctc cgataatgcc actagataaa ctaacaatac caatagtaga
    10561 aaccatatct catcctccta gaaatagatt gagcctattt tatcacaaaa tataagagaa
    10621 agctatgtgg gatttcagaa gaatactttt aatactcttc gaaaatctct tcaaaccacg
    10681 tcagttttat ttgcaacctc aaagctgtgc tttgagcaac ctgcagctag cttcctagtt
    10741 tgctctttga ttttcattga gtataactca aaaaagtaag tgaaaaagca accgcacctg
    10801 cagttgcttt tatcgttttc ttattcttga tagcgtgttg gtcctgcact tgcactacgg
    10861 atattcaagc gtttcttgag atagaagcga agggctagga gggctgctcc aataatagct
    10921 agtggcaatg gatccagtac tgggttaagg ctagctggta ggaagcttgt tgcaaagaag
    10981 acaagcaacc aaaggaacat agaagctagg ataactagta cagatttcca gaaaggtgga
    11041 cgttgactgc ggtccatatc tggtccatag tattggtaaa caaagtagta catcaagtag
    11101 aaggcaaatc caccaaccag tccaactaat agaagagtaa tcaatccata gccgaaagct
    11161 tgatctgccg caaagaaggt tgtgagggcg ctgacaaggg caaagaggct agtgatgaaa
    11221 agagctgagt ccataatcat cagttttgga tcatcatttt cttttggatg ctctttttcg
    11281 tactgctctt tgacagtgaa gctatgagcc caatgagttg gtgcgccgta tagggaacgg
    11341 gcagttgtac ctttagattg ctcctcaagg atttggggaa tgacttcctc aaaaatagtc
    11401 tggatttcag cgtctgtttt cccatctttg atgaattgtt gggtagcaat gtggacaaac
    11461 tcttggtttt tcttagttaa tttttgtaga tcaatttgag acataggaac tcctcttaga
    11521 accatttttt atggatgaga tagagagtga gcgagacact catagcaaag gcgataaaga
    11581 cgattaacca gaaggcattt ggctctccgt ttagggggat ttcattatcc ttaaagttca
    11641 tcccgtaggc agaaaagacc atggttggga tggacatgac gatggtcaca agggccaagg
    11701 ttttcatgat gttgttctgg ttgttagaaa tgatagaggc aaaggtctct gtcatagaat
    11761 gcaagacgtt tccataaata tctgccatct cgatggcctg ttgggtttca atcagggtgt
    11821 cttcaagcag gtcttcgtcc tcaaggtatt tcttgatatt gctggttgaa ctggtcaatt
    11881 tcttaatcac gcgctcattt gttttgaggg aggccttgaa atagacgata gttttttcca
    11941 attccatgag ctcaatcaat tcttcattac gagttgattg atgcagttga ctttcgattt
    12001 gttcactctt gcggtcgatt gaacgaaggg ctgttaggta aagctctgca ttgcgataaa
    12061 gaatttgaaa gataaaacgt gaacgcatga aggtatagaa attacgcaat cgacggttga
    12121 taaagacatc aaggacaggt agtggttcca aacacgtagt gataatggtt tcctcagtga
    12181 tgataatacc aagcgggatg gttacgtagt aggtgcggtt atttctttcc tccgtgaccg
    12241 gcacgtctac gataatcagg gtatactcgt cttcaatggt aatacgagac atttcttccg
    12301 catcgagcgg tgctcgaagg tcggcaatat caatatcgaa ggtgttggcg atttcgagtg
    12361 attcattttg agtcggattg acgagattga tccaagtacc cggttcaagc gtatcgatct
    12421 ctttaaattc agttgttgta gagagaaaaa cttgtttcat atcccttatc ctttctcatt
    12481 tttcagattt tttcacactg tactattata ctacaaaatc ggccttttgg gtaatagaat
    12541 ctcacttttt ttggtataat ggtaagcaat aatggactag aaagaacaaa gatgcaagat
    12601 aaaattgtca ttcatggggc gcgtgcccat aatttaaaaa atattgatgt ggagattccg
    12661 cgagacaagt tggttgtcgt gactggcttg tcaggttcag ggaagtccag tctggctttt
    12721 gatactctct atgcggaggg acaacgtcgc tatgtagaga gtttgtccgc ctacgctcgt
    12781 cagttcttgg gaaatatgga aaaaccagat gtagatgcca ttgatggtct cagcccagct
    12841 atttccatcg accagaaaac gactagtaaa aatcctcgct cgacggtggg aacgacgact
    12901 gaaatcaatg actatctgcg tctcctctac gcacgtgtgg ggacgcctta ctgtatcaac
    12961 ggacatggag ctatcaaggc ttcttctgtg gagcaaatcg ttgataaggt tttggagtta
    13021 cctgaacgcc agcgcttgca gatcttggct cctgtcatcc gcaagaaaaa aggccaacat
    13081 aagagtgtta tcgagaaggt tcagaaagac gggtatgttc gtgttcgtgt ggatggggaa
    13141 gtctatgatg tgaccgaagt gccagagttg tctaagagca agcaacacaa tatcgatgtc
    13201 gtggttgacc gtattgttat caaggagggc attcgtagtc gtctctttga ttccattgag
    13261 gctgcccttc gtattgcaga aggttatgtc attatcgaca ccatggacga ttcggagttg
    13321 ctcttctctg agcattatgc ctgtccagtt tgtggtttta ctgtcccaga gttagagcct
    13381 cgtctcttct ctttcaatgc tccttttggc tcttgtagtg agtgtgacgg cttgggcatc
    13441 aagctggagg tggatactga tttggtagtg ccagatgcca gcaaaacctt acgtgaggga
    13501 gcgctagcac cttggaatcc tatctcatcc aactactatc caaacatgtt agagcaggcc
    13561 atgaaagtct ttggagtggc tatggataag ccttttgagg acctgtcaga agaagataag
    13621 aacttgattc tctatgggtc agatggtaag gaattccatt tccactatga gaatgaattt
    13681 ggtggcgtgc gcgatatcga cattccgttt gagggagtta tcaataatat caaacgtcgt
    13741 taccatgaaa ccaatagcga ttacactcgc actcagatgc gtctctacat gaatgagctg
    13801 acctgcggaa cctgtcaagg ctatcgtctc aatgaccagg ccttgtctgt ccgtgtgggc
    13861 ggccagcaag ggccacatat tggagaaatc tcagacctgt ctatcgctga ccacttggac
    13921 ttggtgagcc agttaacttt gtctgaaaat gaagccatca ttgctcgtcc cattctcaag
    13981 gaaatcaagg atcgtttgac cttccttaat aatgtgggtc ttaactatct aaccctgtca
    14041 cgttcagcag gaaccctttc aggtggggaa agtcagcgca ttcgtttggc aacccagatt
    14101 ggttccaacc tatcaggcgt cctctatatc ctagacgagc cgtcaatcgg tcttcaccag
    14161 agggacaatg accgcctgat tgccagtctg aaaaagatgc gtgacttggg caatactctt
    14221 atcgtggtgg aacacgacga agataccatg cgtgaggctg attatctgat tgacgttggt
    14281 cctggtgccg gtgtttttgg tggtgagatt gttgcagcag gtacacctaa gcaagtggct
    14341 cgcaacagca agtctatcac aggtcagtac ttgtcaggca aacgtgtcat cccagtacca
    14401 gaagagcgcc gtgtcggaaa tggtcgtttt attgaagtga taggagcgcg tgagaacaac
    14461 ttgcaaaatg tcacggctcg ctttccacta ggaaaattta tcgcagtgac aggtgtgtcg
    14521 ggttcaggga aatcgactct aatcaacagc attctcaaaa aagccattgc ccagaagctc
    14581 aaccgtaatt cagacaaacc tggtaagttt aagactatta cagggattga gcatgtcgac
    14641 cgtttgattg atattgacca gagccctatc ggacggacgc cgaggtctaa cccagctacc
    14701 tatacaggag tttttgatga tatacgtgac ctttttgctc agacaaatga agccaagatt
    14761 cgaggctaca agaaggggcg cttcagtttc aacgtcaagg gaggtcgctg tgaagcttgc
    14821 tcaggtgacg ggattatcaa gattgagatg cacttcttgc cagatgttta tgtggcttgt
    14881 gaagtttgcc acggaacccg ctataacagt gaaaccctag aagttcacta caaggaaaag
    14941 aatatttcgc aggtcttgga tatgacggtc aacgatgcgg tagaattttt ccaacacatt
    15001 ccgaaaattc aacgcaaact ccagaccatc aaggatgtag gtctaggcta tgtgaccttg
    15061 ggacagccag ctaccaccct ttctggggga gaagcccaac gtatgaagtt agctagcgaa
    15121 ctccacaaac gctcgacagg aaaatctttc tacattctgg atgagccgac gacagggctt
    15181 catacagagg acattgctcg cctgctcaag gttttagctc gctttgtaga cgatggcaat
    15241 acagtcctcg tcatcgagca caatctggat gttatcaaga cggcagacca tatcattgac
    15301 ttgggacctg agggcggtgt cggtggtgga accatcatcg taacaggaac tccagaagaa
    15361 gtagctgcca acgaagccag ctatacagga cactatttga aaggaaagtt acatcatgga
    15421 taaacgcgta caagcatttc tagctaaaat gcaagaaaaa gaactagatg gtatcatcat
    15481 caacaatctt aaaaacgtct attatttgac tggtttttgg ggctcaaacg gaacagtctt
    15541 tatcagccgt gaccgtcagg tcttagtgac agactctcgc tatatcatcg cagctaagca
    15601 agaaaccagt ggttttgaga ttgtggctga tcgtgatgaa ttggctgtca ttgcaggaat
    15661 tgttaaggac atgggcttga ctcgtatcgg ttttgaagat gagatttcag tgtcttatta
    15721 ccaccgtatg caggcagctt ttgcaggttt ggacttgctt ccacaaactc agtttgtgga
    15781 aggtcttcgt atgattaagg atgaggcaga gattgcagcg attcgcaagg cttgttctat
    15841 ctcagaccaa gctttccgcg atgcgcttga ctttatcaaa ccaggaaaaa ctgaaattga
    15901 gattgccaac ttccttgatt tccgcatgcg tgagttggga gcatctggct tatcttttga
    15961 tacgatccta gctagcggta tcaattcttc taaaccccat gcccatccaa tgcacaaacc
    16021 agtggagttg ggagaagcca ttaccatgga cttcggctgt ctctatgacc actatgtcag
    16081 tgatatgacc cggactatct atctagggca tgttagcgat gagcaggcag agatttacaa
    16141 tacggttcta aaagctaacc aagccttgat tgaccaagct aaggcaggct taggtttccg
    16201 tgactttgac aaaatccctc gtgatattat cattgaggca ggttatggtg actactttac
    16261 tcacggcatt ggccacggta ttggtctgga tatccatgag gaaccctact ttagccagac
    16321 ttctacagaa actattaaga caggtatggc cttgaccgat gaaccaggta tctatatcga
    16381 aggcaaatat ggcgttcgta tcgaggatga tatcctgatt acagagacag gttgtgaatt
    16441 attgacccta gctccaaaag agttgatagt catttagttg tttgtcaaga aaaaagtacg
    16501 aaaatgacga aaaaagtcaa aaaaaattaa aa
//
LOCUS       DAVKAU010000042        15432 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVKAU010000042 DAVKAU010000000
VERSION     DAVKAU010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15432
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.042"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..1180
                     /locus_tag="VWX48_001545"
                     /pseudo
     CDS             1..1180
                     /locus_tag="VWX48_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1265..2467)
                     /gene="rpsA"
                     /locus_tag="VWX48_001546"
     CDS             complement(1265..2467)
                     /gene="rpsA"
                     /locus_tag="VWX48_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU9172147.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2629..2700)
                     /locus_tag="VWX48_001547"
     tRNA            complement(2629..2700)
                     /locus_tag="VWX48_001547"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2666..2668),aa:Gln,seq:ttg)
     gene            complement(2710..2790)
                     /locus_tag="VWX48_001548"
     tRNA            complement(2710..2790)
                     /locus_tag="VWX48_001548"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2754..2756),aa:Tyr,seq:gta)
     gene            complement(2840..3070)
                     /locus_tag="VWX48_001549"
     CDS             complement(2840..3070)
                     /locus_tag="VWX48_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU9172148.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3238..3882)
                     /gene="pcp"
                     /locus_tag="VWX48_001550"
     CDS             complement(3238..3882)
                     /gene="pcp"
                     /locus_tag="VWX48_001550"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU9172149.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3897..4820)
                     /locus_tag="VWX48_001551"
     CDS             complement(3897..4820)
                     /locus_tag="VWX48_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU9172150.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4817..5506)
                     /locus_tag="VWX48_001552"
     CDS             complement(4817..5506)
                     /locus_tag="VWX48_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU9172151.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIVTVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5571..6275)
                     /locus_tag="VWX48_001553"
     CDS             complement(5571..6275)
                     /locus_tag="VWX48_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9172152.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            complement(6331..7353)
                     /locus_tag="VWX48_001554"
     CDS             complement(6331..7353)
                     /locus_tag="VWX48_001554"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU9172153.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEYATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7483..9954)
                     /gene="parC"
                     /locus_tag="VWX48_001555"
     CDS             complement(7483..9954)
                     /gene="parC"
                     /locus_tag="VWX48_001555"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU9172154.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(10374..12317)
                     /gene="parE"
                     /locus_tag="VWX48_001556"
     CDS             complement(10374..12317)
                     /gene="parE"
                     /locus_tag="VWX48_001556"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU9172155.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12453..13094
                     /gene="plsY"
                     /locus_tag="VWX48_001557"
     CDS             12453..13094
                     /gene="plsY"
                     /locus_tag="VWX48_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU9172156.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            complement(13175..14404)
                     /locus_tag="VWX48_001558"
     CDS             complement(13175..14404)
                     /locus_tag="VWX48_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9172157.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYG
                     LAKQLRFHIVQHLSRAMSRVRVQIMNQFHRKFHEYKAIKRYWKLIQQDSRKLSDKRFY
                     RPTFRIHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVH
                     PIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIF
                     IALNIKKERTKFVLSRA"
     gene            complement(14533..15432)
                     /locus_tag="VWX48_001559"
                     /pseudo
     CDS             complement(14533..15432)
                     /locus_tag="VWX48_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4464 a         3376 c         2751 g         4841 t
ORIGIN      
        1 atgaagaaat atgactttca aaaaccttct aaaattcctt atcttgaaac gactggtatg
       61 ccttctagaa ttctccttag aaaacgccgt ttcaagtgct atcactgttc aaaaatgatg
      121 gttgctgaga ctcccctggt aaagaaaaat caccaaatcc ctcgtatcat caaccaaaaa
      181 attgctcaaa agttaattga aaagatttct atgactgata ttgcccatca gctttccatc
      241 tcaacttcaa ctgtcattcg caagctcaat gattctcact ttgagcatga tttttcgcgt
      301 cttcctgaga ttatgtcctg ggacgttgaa acagtccggg gagtgactgt ttcaatcggg
      361 agatggagat gagcttcatt gcgcaagatt ttaacaatct caatatcatc actgttcttg
      421 agggaagaac acaagctatc attcgaaatc actttcttcg ctacgataga gctgtccgat
      481 gtcgcgtcaa aattattact atggatatgt ttagccctta ctatgacttg gctaaacagc
      541 ttcgctttca aatttctagg ctcaggctga aacagtctcc caggctgttt cactcccgaa
      601 tgctaaaatc gttcttgatc gctttcacat tgtacaacat cttagccgtg ctatgagtcg
      661 tgtgcgtgtt caaatcatga atcagtttca tcgaaaattc catgaataca aggctatcaa
      721 gcgctactgg aagctcatac aacaggatag ccgtaaactg agtgataagc gattttatcg
      781 tcctactttt cgtatgcact taaccaataa agagatttta aacaagcttt tgagctattc
      841 ggaagacttg aaacaccact atcagctcta tcaactcttg ctttttcact tccagaataa
      901 ggaaccagag aaatttttcg gacttattga ggacaatctt aagcaggttc atcctatttt
      961 tcagactgtc tttaaaacct tcctcaaaga taaagaaaag attatcaacg cccttcaact
     1021 acactattct aacgccaaac tggaagcgac caataatctc atcaaactta tcaagcgcaa
     1081 tgcctttggt tttcggaact ttgaaaactt caaaaaacgg atttttatcg ctctgaatat
     1141 caaaaaagaa aggatgaaat ttgtcctttc tcgagcttag ctgacttcaa cccactacag
     1201 ttgacaaaga gccagaaaaa tcccttgttt agtaaacaaa ggattttgtg aattttcaat
     1261 ttgattaaag ttcgatatca ccaaacaaat cagccattga aaatcctgtt tgtgtttctg
     1321 gaagttcgaa atcacgcttt tcttgacgtc ttggacgacg tggacgagca gcacgttttt
     1381 cttctttttg tccttcttct tgggctggac gttcttcaag agctttaata gaaagtgaca
     1441 cgcgttctgc atctgcgtta acttcaagaa ctttaacttg aacttcttga ccaactttaa
     1501 gagcttcttt tggattttca atccgtttgt gtgaaatttg tgatacgtga acaagtccat
     1561 cgatacctgg caatacttca acaaatgcac cgaagtcagt caaacgttta actgttcctt
     1621 ctactacatc acctttagcc aatttttgct caacgccatc ccatggtcct ggtactgttg
     1681 ctttaagtga aagtgataca cgtccttctt cttcgttaag atcaaggatt ttcacttcaa
     1741 tttcttcacc aacagttaca actgattttg gtgatacgtt acgttcatgt gacaattcag
     1801 tcaagtgaac caatccgtca acaccaccaa ggtcgatgaa agcgccgaag cttgtgatac
     1861 gagcaacttt accagttaca acatcaccaa cagccaattt accgaatact tcagcgcgag
     1921 ctgctgcagt agctgcttca acaacttcac gacgtgaaag gatgaagcgg ttttctttag
     1981 cgttaacttc tttgatttta gtatcaaatt cttgacctac aaaacgctca gcgttacgta
     2041 cgaaacgagt atccaacatt gaagctggga taaatccacg aacaccttca aattctactg
     2101 aaagtccacc tttaacggca cgcgttcctt taacagtaac aacttcttct tcgcgaccaa
     2161 caagtttgtc ccatgctttg cgagcttcaa ggcgtttttt agatacaagg tatgtaactg
     2221 tatcagtatc tttaccaact acttgacgaa gtacaagaac atccaatact tctcctactt
     2281 taacaaagtc attgatatct gcatcacgat cgtttgtcaa ttcgcgaaga gtcaagacac
     2341 cttcaacacc agttccagag attgcaacgt tagcttgagt cgcatcaact gtcaatactt
     2401 cagcactaac aacatcacca gtctcaactt gactaacgct atttagcaaa tcttcaaatt
     2461 cgttcatcta aaaaatcctc caacaatcaa gtttttctta aacttgacat acttataatt
     2521 tttttcctaa gcacccgcaa ggacatgttc atatcattca cgtctttcaa ttataaaaat
     2581 aaaataccct aagatatttt gctttctatc ttgattatta cctaagaact ggggtagctg
     2641 gattcgaacc aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca
     2701 ttaatgaaat ggagagagag ggattcgaac ccccgaaccc gaaggagcgg atttacagtc
     2761 cgccgcgttt agcctcttcg ctatctctcc tacaatcaac atggactatt atatcatgaa
     2821 aatttcaaaa aaacaagact tattttgcta aattataatt ttcaatcaaa atttccacag
     2881 ctttttccaa ttttttataa aaactatcga cattcccatt ctttataatg gcaaattgtc
     2941 cgtctaattc ggcaatttct ccgataactt ttttaccgat agtcaatgta taaccttcaa
     3001 aactgtcttt accaacatta actttggcat ccgctacttg aatttcgatt tttttatctt
     3061 tcttgctcat ttcatacctc tcttcacttt ttctatttta caagaaaatc ctaaaactag
     3121 caagaaaaaa ctctatatca ggcttctctg atatagagtt ttatgtaaac aacctcaatt
     3181 gatttagcat agttaatagt tagtaaacaa gcataattga ctatcctttt taggttatca
     3241 gtgagtctca ccgcctacta actgcaaatc cttatctttg tagtctacaa tagcttcaat
     3301 agctacctct atgcctctta caatatcaca tagactcatt cctgcagtat tcggcttatt
     3361 tactacttgt tccatcatat atggaatatg catgaaacct gctctcatat tagggaattt
     3421 tttatccact aaataaagag cttggtacat caaatgattg caaacaaagg ttcctgcact
     3481 attggataca actgccggaa gtccctgttt tttgatagct tgtaccatcg ctttgatagg
     3541 taaactacta aaataggccg atgctccatc aatacgaatc ggtgtatcaa ttggttgatt
     3601 gccttcgtta tcaggtatgc gagcatcatc ttgattaata gccactcgtt caggtgttaa
     3661 gccggtcctg ccgcctgctt gtccaataca aagtacagca tctggttgat atcgtaatat
     3721 ttctgcctct aaaacttctg acgacttata aaaaaccgtt ggaatttcta cccagcgaac
     3781 ttcagcccca ttaatctcag atggtaataa ttttacagcc tccaaagctg gattaatctt
     3841 ttcacctcca aaaggattaa aacctgtaac caatattttc attttatttt cctttactaa
     3901 aatgcgagaa agtacattaa gaatatgtga ataacaatca ttactagagc aacacctgct
     3961 tgagccttta taacgccatt ctgatctttc atatccatca atgctgctgg tagagcgtta
     4021 aaattagcag ccattggggt caataaggtc ccacaataac ctgctgtcat ggcaagagca
     4081 ccagccacaa ttggattagc tcccagagca aatacaaagg gaactccaac acctgctgta
     4141 ataacggtga atgctgcaaa agcatttccc ataatcattg tgaatagaac cattccaaga
     4201 acataagcca aaactcctat aaagcgacta tctgaaggaa caataccgct aatcagatga
     4261 gagataacat caccaacacc tgctacagta aaaatagccc ccaaagcccc taataattga
     4321 ggaacaatcc cacttgttga aacttgctga gtcattcgat tattttctga taacagactc
     4381 ttagggtgac tattggtaat cacaagaaca gaaattgtag caaacaaggc ggcaaggcta
     4441 atcgaaatct tgctaaattc tggaatcatt tgcgctaaga ccaacgcaag tattgccatc
     4501 agcataactg gaataaaaat tttatttttc aatctgttag attcaatatt ggctttcatt
     4561 tcatctaagg atggcaaggt tccgatacgg acttgcttaa acaatgttaa cagcgataat
     4621 aggattacaa taataccaat actcatattt ggcatatagg aaccacctat aaacgtaata
     4681 gacaatagag tccaaaatgc agatgtccca agtcgaactg ggtttgtttt atctttataa
     4741 ctacaatagg ctgtatggag aaattgacaa ccaatcacaa tataggtcaa ctctaatagt
     4801 tgctttgcca actctgtcat ttttgttctc ctcccctagt cttttttgat atcaattttt
     4861 tatcaaataa ataattgtaa atccccacta caataagtgt tataacagca acaataatag
     4921 atgtagaagc aatccctgca taattgcttt catagcctaa ctgatctaat gttcccccta
     4981 tcaagaggac tcccccagca cctacaaacg tattttgagc aaagaaattt ccaaaatttt
     5041 cattcgcagc cgcacgcgct tttattgtct catcttcaac ctctgttaac tttctaccta
     5101 attgagactc tgcagctgct tctcccatag gttgaaccaa aggtctgaca aactgagggt
     5161 gtcctcctag acgaattgaa aagaaaccag ctaactctcg aataaagaaa taaactgtat
     5221 agaagtttcc aactgtcaga cctttaatct ttcgaatcaa atcgattgat cgttgcttga
     5281 gtccaaaggt ttctgacagc cccacaagag gcaaggtaac cataaaaatc gtgagcactc
     5341 gctgattgct aaattctttt cccaaaatct ccaaaaattc aacgagagaa acacctgaaa
     5401 ctaaagctgt aaccaaacca gctaagacta ctgttacaat tgtatcaaat tttaaaataa
     5461 aacccacaac aatgattgct attcctatta atctaatcca ctccatatca aactccttta
     5521 tattcaaaat gacagtattt taaaaatttt atcaagatca ataccattcc ttatttaatg
     5581 tatttttcta gttctttttg gtatttgcta ttggattcca atttttcttt ttgccatttt
     5641 ttaaaaacct cgttatattc ttttgttgta acaatatctt tttgcaattt cattccttta
     5701 aagatatatg gttccccctt aataccaact tgtgagtatg gttttgagaa tggtactacg
     5761 ttacttacaa ctggagaacc accagatgaa gctgttggca tcaataatga actatctgtc
     5821 gaccaagctt gagctttggc atatttttca tatctcttct ctaggtcagt ggtctcagaa
     5881 acagcatctt ctaacaattt cttatattta tccaaaccag gtttagctac aacatcctta
     5941 tcttttcctt tcgtaatgcc aaggtgtttc atggcagaac cagattttgg atccataata
     6001 ttcaagtaag acgctggatc ttgatagctt ggagcccatc ctgtactgtt caaatcatag
     6061 tctttttgag aaggagcaac attgccgtat ttatcatttt ccatcaaacc atcaataaca
     6121 tttccaataa cgtctgtcct cgatgttcga gtcgctatac tgtagcccaa tgatgctgga
     6181 tctactgcat agacataaga aaatgttgtc ggtgcatctg cttctttatc agtttttcca
     6241 caagccacta aaatagctga cgtgctcagg accactcctg ctgttaagag ccactttttc
     6301 tatttcataa aaaatctcct ttggtttatt ttaatctact tttacaatcc aaccttctgg
     6361 cgcttcaata tcgccaaact gaatacccgt caattcatta tataatttac gcgtcacagg
     6421 acctacttct gtttcactat agaatacatg gaaatcatca ccatgttgaa tacctccaat
     6481 tggagaaata accgctgctg taccacaggc acctgcctct acaaaacggt caagattatc
     6541 aattggaaca tcaccctcaa taggagttaa tcccaagcga tgttctgcca aataaagcaa
     6601 ggaatacttg gtaatagatg gcaagataga tggactcaat ggtgttacaa attcattatc
     6661 agctgtaatt ccaaagaaat tagctgatcc gacttcttca atctttgtat gagttgatgg
     6721 gtccagatag ataacatctg agaaatggcg tgacttggcc atttttcctg gtaagagact
     6781 tgcagcatag tttccaccaa ccttagccgc acctgtacca tttggtgctg cacggtcgta
     6841 ctcatcctga atcaagaagt tggttgggac caaaccacct ttaaagtaat ttccaactgg
     6901 catagcaaag atggtgaaaa tgtactcttc tgccggtttt accccgataa tatctccgac
     6961 accaatcaaa agagggcgaa gatataaagt tccacctatt ccgtatggtg gtacgtattc
     7021 ttcattcgca cggacaactg ctttacaagc ttctacaaac atgtctgtcg gaacttgtgg
     7081 catcaagaga cggtcacatg tacgttgcag gcgtttagca ttttcatcag gacggaacag
     7141 ttgaacactg ccatccttag tacgataagc tttcaaacct tcaaatgctt gttgtccata
     7201 gtgaagactt ggagaagact ctgaaatatg caaagttgca tactctgtaa gctctccttg
     7261 atcccattgt ccatttttga aatgagcaag atagcgataa ggtaatttca tataggaaaa
     7321 accgaggttt tcccaatcaa tcgttactgt catattccac tccttattct aaaaacctat
     7381 ttcttatatt ctacactatt tttctaaaat agcaagtata ttttgtaatt ttcagaaaat
     7441 ttctccaata aaaaccatct tagaactgat tcttcatttc acttatttat cttcagtaac
     7501 tacttcctga agataagcgt caaaaacttc ttcatctgaa atcgtgtcag aaatgaagct
     7561 tccattgcta gtgcgttctg acaagttcaa gtcttgcaat cggctttcat agattgttcc
     7621 tttattggat tggacaagca gagtttggtc gttcacatcc acttccgtac tgaagaaatc
     7681 gccaacaaat ccttgctctg caactgctcc tgccaagaag acacgatgcg gtttgttttt
     7741 caactcacgc aagacttgta atcctcgttt ggcacggctg gttgctagaa tttcctcaat
     7801 ggaaacacgt ttcaagcttc cacgctgggt caagaggtag aaggacgaag tattacagat
     7861 aaagccagat tggaggacat catcttcttt caaattcata gccttgacac ctgctgcctt
     7921 agcaccgaca accggaacct cttcgatatt gaaacgcagg gcataaccat tttgactaac
     7981 caagacaaca tcatctagtt taatcggagc cactgctaca atctgatctg tatcgtcttt
     8041 gagcttagca tacttgacag acttagatct ataggtccgc catggagtga attcttttcg
     8101 ctctacccgt ttgatttgac caaggcgagt cgctgcaaag taggttgtcg catcgtcaaa
     8161 ctgatccagt acttccacat aaaggattgc ttcattcgtt tcaaagtttg tgatggtttg
     8221 gctcagatgc tctccgatgt ccttccaacg aatatctgcc aactcatgga ttggtctgta
     8281 gatgacattt ccaagacttg tgaacatcaa gaggtgctgg gttgtcttgg cagattgaac
     8341 aaaaatcaaa cggtcatcat cacgcttgcc aatttcttcc aaggtggaag ccgcaaagga
     8401 acgtggactg gtacgcttga tgtaacctgc cttggtcacg ctgacgtagg tatcttcctc
     8461 agcgataaga ctagctgtat caatctcaat tgctttcgca gtgtcttcta aagaactcaa
     8521 acgaggagtt gcaaatttct tcttgacctc acgaagttct ttcttcatga gattgtacat
     8581 agtcctttca tcaccgataa tagccaccag catagcaatc ttctcacgaa gctctgcttc
     8641 ttcttcctgc aagacaacca catcggtatt ggtcaaacgg tacagttgca aagttacgat
     8701 agcctcagcc tgttcttccg taaaatcata gctaactttg aggttttcct tggcgtccgc
     8761 cttattctca gaagcacgga taagagcaat gacttcatcc aaaatcgaaa tcacacgaat
     8821 caaaccttcg acgatatgga gacgtttctc agccttttct ttgtcaaagc gtgaacgcgc
     8881 caaaatcact tctcgacggt gagcgatgta gctagacagg attggaacaa tcccaacctg
     8941 acgaggtgtg aaattgtcaa tcgccaccat attaaagttg tagttgattt gtaggtcggt
     9001 gtacttaaat aagtagttga gaacaagctc agtattagcg tctttcttaa gttcgatagc
     9061 gatacgaaga ccatcacggt cagactcatc acgaacctca gcaatcccag ctaccttgtt
     9121 attaacacga acatcatcga ttttcttgac tagattggcc ttattgattt cataaggaat
     9181 ctcagtaata acgatttgtt ccttaccacc ttttagcttt tcaatttcag tcttggaacg
     9241 aacaaccacg cgccctttcc cagtctcata agctttcttg atttcatcac gaccctgaat
     9301 aatagcccct gtagggaagt ctggtccagg caagaattcc atgagtttat caatctttgc
     9361 agttgggtgg tcaatcatgt aaactgcagc atctatgacc tcagctaaat tatggggagg
     9421 aatgtctgtg gcataaccag ccgaaatccc agtcgaacca ttgaccaaga ggtttggaaa
     9481 ggctgctggc aagaccgttg gttctttctc cgtatcgtca aagttccatg caaaaggaac
     9541 tgtctttttc tcgatatcct gaagaaggta gcctgcaatt tcagacaaac gtgcctcagt
     9601 ataacgcata gccgcaggag gatctccgtc catagaaccg ttattaccgt gcatttcaac
     9661 tagaatctca cgatttttcc agttctgtga catacgaacc atggcatcat agatagaaga
     9721 atccccgtgt gggtggaaat tccccatgat gttcccgact gacttggccg acttacggta
     9781 gctcttgtca aaagtattgc tatccttatt catagaataa agaatacggc gctgaaccgg
     9841 cttcaaccca tcacgaatat ctggcaaagc ccggtcttga ataatgtact tggagtagcg
     9901 accaaagcgc tctcccatga tgtcctccag ggacatgttt tgaatgttag acataagata
     9961 caaagcccat aaaataccaa gtgaaaatag aaaattcttg aagtaagcaa actcacaaga
    10021 gaatttatct ttttcacaca gtatctaggg cgtgttcaac tcctttcaaa gaatgtagag
    10081 taggttttta tgcagtaaaa gatattttac gggaattcgt cccgtgttca gttacgataa
    10141 gtaaccaaac tatcctgttt gtatttttca atatgaaaat atggttttcc aaaattagtc
    10201 ttagtttgtg tcttagccgc tcccttaaac gcctctttga gataagcact catagcagat
    10261 tcttcattaa taatcctgca attttttcaa accaagattt tcaaactgct ttttcacata
    10321 gtcattcaca tccgactcta atttccagtt tactaacata ttattttctt tcattaaaac
    10381 actgtcgctt cttctagcgt aaacttgaca ttatcttcaa tccatttacg gcgtggttct
    10441 accttatctc ccatgagaac attgacgcgg cgttcggcgc gcgctaaatc ttcaattgtg
    10501 acacggatga gggtacgtgt ttctgggttc atggttgttt cccagagctg gtccgcattc
    10561 atctcaccaa gtcctttgta tcgttggagg gtagcgcctt taccgaactg tttacggagt
    10621 tcttctagtt ctccgtccgt ccaagcgtag gccacttctt ctttcttgcc tttacctttg
    10681 gacatcttgt aaagaggtgg gagggcaata tagacatgac ctgcctcgac tagcggacgc
    10741 atgtaacggt agaaaaatgt caagagcaag gtctggatat gggcaccgtc ggtatccgca
    10801 tcggtcatga taatgatctt atcatagttg gcatcttcaa tagagaagtc tgctccaaca
    10861 cccgcaccaa tggtataaat catggtattg atctcttcat ttttgaggat atccgccatc
    10921 ttggccttgg ctgtattgac aaccttacca cgaagaggta gaatagcctg gaacttgcgg
    10981 tcacgacctt gtttggcaga accaccggca gagtccccct caactagata gagttcattc
    11041 ttagcaggat tcttagattg ggctggggtc aatttcccag acaacaagcc cttatctttc
    11101 ttgtttttct tcccatttcg gctctcatca cgcgccttac gtgctgcttc acgagcatca
    11161 cgggccttga tagccttgcg gatgaggtta gaagctaatt ccccattttc cataaggaaa
    11221 aaggtcaact tatcagccac tattccatcc acaactgggc gagctagggg gcttcctagt
    11281 ttatccttgg tctgtccttc aaactgcaag tgttcttcag gaactaagat agaaagaacg
    11341 gccgctagtc cctcacgata gtctgaacct tcaaggtttt tatctttttc cttgagaaga
    11401 cctgttttac gtgcatagtc attcatgacc ttggtaatgg cagacttgag tcctgtctcg
    11461 tgcgttccac cgtccttggt gcgaacgtta ttgacaaagg atagaatgtt atctgagaat
    11521 ccgtcattgt actggagggc tacttccact tgaaaaccat tgtcttcccc ttcaaagtaa
    11581 agaactggcg tcaagatttc cttatcttcg ttgagataag aaacaaaatc ttgtactcca
    11641 ttctcatagt ggaactcaat cgcttcatct gttcgcttgt ccgttaaaga caaggtcaca
    11701 tttttcaaga gaaaggctga ttcattaagg cgctctgaaa tggtattgta cttgaaatct
    11761 gtcgtagaaa agatagtcgc gtcaggcata aaagtaactt tggtgcctgt tttagacttg
    11821 ggtgctgtac cgattttctt caaagtcgtg acaggttttc caccattttc aaaacgttgc
    11881 ttgtaaactg cgccatcacg ggtaatttca acttctaacc agctagaaag ggcgttaaca
    11941 acggaagaac ccactccgtg aagtccacct gatgtcttat agccaccttg accgaatttc
    12001 cctccggcat gaagaatggt aaagataacc tcaacagttg gaattcccat agcgtgcata
    12061 cctgtcggca tcccacgtcc atggtcttga accgttagac taccgtcttt attgatagtt
    12121 acatcaatac gatcaccaaa cccagacaag gcttcatcga ctgcattatc aacgatttcc
    12181 caaactaggt gatgaagacc agcgccatcg gtcgatccaa tatacatccc tggacgtttt
    12241 cggaccgcat ccaacccttc tagcacctga atagcatcat cattataatt gttaatattg
    12301 atttcctttt ttgacacaag gaacctccta ttcgttcatc tttactattc tacaggtttt
    12361 ccaaggattt tgcaaaattt ttctttctcc gatgtgacaa tttcagcaga gattctctgc
    12421 ttttctttcc caattcatga tataatagga gtatgattac aatagtttta ttaatcctag
    12481 cctatctgct gggttcgatt ccatctggtc tctggattgg acaagtattc tttcaaatca
    12541 atctacgcga gcatggttct ggtaacactg gaacgaccaa caccttccgc attttaggta
    12601 agaaagctgg tatggcaacc tttgtgattg actttttcaa aggaacccta gcaacgctgc
    12661 ttccgattat ttttcatcta caaggcgttt ctcctctcat ctttggactt ttggctgtta
    12721 tcggccatac cttccctatc tttgcaggat ttaaaggtgg taaggctgtc gcaaccagtg
    12781 ctggagtgat tttcggattt gcgcctatct tctgtctcta ccttgcgatt atcttctttg
    12841 gagctctcta tcttggcagt atgatttcac tgtctagtgt cacagcatcg atcgcggctg
    12901 ttatcggggt tctgctcttt ccactttttg gttttatcct gagtaactat gactctctct
    12961 tcatcgctat tatcttagca cttgctagtt tgattatcat tcgtcataag gacaatatag
    13021 ctcgtatcaa aaataaaact gaaaatttgg tcccttgggg attgaaccta acccatcaag
    13081 atcctaaaaa ataaaacgcc agttctgtac tgcccccaaa cagttagaca aataatttat
    13141 ggctctttgt caactgtagt gggttgaaga aaagctaagc tcgagaaagg acaaattttg
    13201 tcctttcttt tttgatattc agagcgatga aaatccgttt tttgaagttt tcaaagtttc
    13261 gaaaaccaaa ggcattgcgc ttgataagtt tgatgagatt attggtcgct tccagtttgg
    13321 cattagaata gtgtagttga agggcgttga caatcttttc tttatctttg aggaaggttt
    13381 taaagacagt ctgaaaaata ggatgaacct gcttaagatt gtcctcaata agcccgaaaa
    13441 atttctctgg ttccttattc tggaagtgaa aaagcaagag ttgatagagc tgatagtgat
    13501 gtttcaagtc ttgtgaatag ctcaaaagct tgtctaaaat ctctttattg gttaaatgta
    13561 tacgaaaagt aggacgataa aatcgcttat cactcagttt acggctatcc tgttgtatga
    13621 gcttccagta gcgcttgata gccttgtatt catggaattt tcgatgaaac tgattcatga
    13681 tttgaacacg cacacgactc atagcacggc taagatgttg tacaatgtga aagcgaagct
    13741 gtttagccaa gccatagtaa gggctaaaca tatccatagt aataattttg acgcgacatc
    13801 ggacaactct atcgtagcga agaaagtgat ttcgaatgat agcttgtgtt cttccctcaa
    13861 gaacagtgat gatattgaga ttgttaaaat cttgcgcaat gaagctcatc tttccctttg
    13921 taaaagcata ctcatcccaa gacataatct caggaagaca agaaaaatca tgtttaaagt
    13981 gaaaatcatt gagcttacga ataacagttg aagttgagat ggaaagctga tgggcaatat
    14041 cagtcataga aatcttttca attaactttt gagcaatctt ttggttgatg atacgaggga
    14101 tttggtgatt cttcttgacg atagaagttt cagcgaccat cattttagaa caatgatagc
    14161 acttgaatcg acgctttcta aggagaattc tagtaggcat accagtcgtt tcaagataag
    14221 gaattttaga aggtttttga aagtcatatt tcttcaattg gtttccgcac tcagggcaag
    14281 atggggcgtc gtagtccagt ttggcgatga tttccttgtg tgaatcccta ttgacgacat
    14341 ctataatttg gatatttgtg tctttgatat cgagtagttt tgtgataaaa tgtaattgtt
    14401 ccatatgaat ctttctaatg agttgttttg tcgcttttca ttataggtca tatgggactt
    14461 tttttctaca caaaaatagg ctccataata tctatagggg atttacccac tacaaatatt
    14521 atagagccta atttatccga aggatttagt tctgtattgc acagggctaa gtccttttag
    14581 ttttatctta attctcttat tgttgtagta atcaatatag tctacaatag cttgttccaa
    14641 ttgcttaagc gactgaaacg acttctcata accgtaaaac atttccgatt tcagaatccc
    14701 aaagaaggac tccatcatac cattgtctgg gctgttaccc ttacgtgaca tggatgcttg
    14761 aactccctta ctctctagga accgatgata agaatcgtgt cggtattgcc agccttggtc
    14821 actatggaga atcgtattct cgtagtgctt ctctgtaaag gcctgttcta acatactctt
    14881 cacttgttct aagttgggcg aagttgaaag attataggcg ataatttcgc tattaaagcc
    14941 atctaaaact ggtgataagt aaagcttttg agtacttgct ggaatggcaa attctgtcac
    15001 atctgtgtag cacttttcca ttgctttaga gccttcaaat tggccttgaa tgagattctc
    15061 tgccttctta ccaacgtctc ctttattttc gtttctgtcg cattttagct tgtaaattga
    15121 gtacttttat caagccttga actcttttat gatttaccag ataagcacga tttcttagtt
    15181 ctaaataaat ccgacgataa gcataatttc ccttgtgttc gataaaaatg gattgaattt
    15241 cagctttaag ctcttggtcc ttatctggtt tgtctagctg tttcaagtga tagtagtagg
    15301 tcgaacgagc tagtttaatg gcttttagaa gaagatctaa cgaaaactca gtcattaatt
    15361 cttgaacaat ttctgtcttt cttctttctc tttttcctcc ttcaatcgga gttctcttaa
    15421 cttttttagg at
//
LOCUS       DAVKAU010000043        15068 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVKAU010000043 DAVKAU010000000
VERSION     DAVKAU010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15068
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.043"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..168)
                     /locus_tag="VWX48_001560"
     CDS             complement(<1..168)
                     /locus_tag="VWX48_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9172158.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINV"
     gene            complement(181..954)
                     /locus_tag="VWX48_001561"
     CDS             complement(181..954)
                     /locus_tag="VWX48_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9172159.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKDLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(1400..2155)
                     /locus_tag="VWX48_001562"
                     /pseudo
     CDS             complement(1400..2155)
                     /locus_tag="VWX48_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2293..3915)
                     /gene="groL"
                     /locus_tag="VWX48_001563"
     CDS             complement(2293..3915)
                     /gene="groL"
                     /locus_tag="VWX48_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU9172160.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(3931..4215)
                     /gene="groES"
                     /locus_tag="VWX48_001564"
     CDS             complement(3931..4215)
                     /gene="groES"
                     /locus_tag="VWX48_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU9172161.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(4485..4880)
                     /locus_tag="VWX48_001565"
     CDS             complement(4485..4880)
                     /locus_tag="VWX48_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU9172162.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(4957..5718)
                     /locus_tag="VWX48_001566"
     CDS             complement(4957..5718)
                     /locus_tag="VWX48_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9172163.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKVNQGHVINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(5751..6377)
                     /locus_tag="VWX48_001567"
     CDS             complement(5751..6377)
                     /locus_tag="VWX48_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU9172164.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(6393..6710)
                     /locus_tag="VWX48_001568"
     CDS             complement(6393..6710)
                     /locus_tag="VWX48_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU9172165.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(6707..7006)
                     /locus_tag="VWX48_001569"
     CDS             complement(6707..7006)
                     /locus_tag="VWX48_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU9172166.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGAIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(7291..7482)
                     /locus_tag="VWX48_001570"
     CDS             complement(7291..7482)
                     /locus_tag="VWX48_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU9172167.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(7643..8317)
                     /locus_tag="VWX48_001571"
     CDS             complement(7643..8317)
                     /locus_tag="VWX48_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172168.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(8323..8769)
                     /locus_tag="VWX48_001572"
     CDS             complement(8323..8769)
                     /locus_tag="VWX48_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9172169.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRIKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(8883..9386)
                     /locus_tag="VWX48_001573"
     CDS             complement(8883..9386)
                     /locus_tag="VWX48_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9172170.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(9383..9745)
                     /locus_tag="VWX48_001574"
     CDS             complement(9383..9745)
                     /locus_tag="VWX48_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEU9172171.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDSLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10054..10770)
                     /locus_tag="VWX48_001575"
     CDS             complement(10054..10770)
                     /locus_tag="VWX48_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9172172.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11651..13066)
                     /gene="ply"
                     /locus_tag="VWX48_001576"
     CDS             complement(11651..13066)
                     /gene="ply"
                     /locus_tag="VWX48_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU9172173.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13077..13409)
                     /locus_tag="VWX48_001577"
     CDS             complement(13077..13409)
                     /locus_tag="VWX48_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172174.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13480..14088)
                     /locus_tag="VWX48_001578"
     CDS             complement(13480..14088)
                     /locus_tag="VWX48_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172175.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSRLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14101..14559)
                     /locus_tag="VWX48_001579"
     CDS             complement(14101..14559)
                     /locus_tag="VWX48_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU9172176.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14684..15068
                     /locus_tag="VWX48_001580"
                     /pseudo
     CDS             14684..15068
                     /locus_tag="VWX48_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4415 a         3366 c         2660 g         4627 t
ORIGIN      
        1 aacattgata tttgataata attcaaaaaa tgttgaaaga gaaatttcat tttctcccct
       61 ttcaaatcta gaaagttgag attttgatat aaaatcagct gcagcatact ctaaagaata
      121 tccgtttaat tttctaaaat atcgaaaagc ttctccgtaa tttttcacac tttcattccc
      181 ttaactttct tttcgagcga taaacatacc atattcttta ggaatgatca acataccatt
      241 attaaactca ctttccaatc ttttacgtat tatttcctct tctagtgaac ctatttctga
      301 aattccttta aatgattgga tgtatttaac taggtcatct atactagtta cctgtaactc
      361 atcatcatag agtaatgtat cgacagagtt aaaataccta ctcaggtacc ttttaccatt
      421 ttgtaaagta aacgttctat tttctaaatc ttgattaacc tcatctttaa ataaacttgc
      481 caaataattt acaactccat tttcaccaaa tgtagcacag taaaaaatgc ctccggtttt
      541 taagacccta ttcacctcag agagagcttt aggaatatca ttcacatgat gtagaagcat
      601 attagcaata acaatatcaa aagtttcatt ctcaaaagaa atcttttgaa tatccattat
      661 ctcataattg acattgtttc tatttccaat cactgacttc gttgatttta ccatatcttt
      721 agaaaaatct gtaacaatca actgcttcat tttatctata gaatcactat tacttttcca
      781 caattctcct gtaccacatc ccaattctag atcctttact tcatcagtga tttggtagtt
      841 agaaaatatc caattattaa atcccaattt attttttgaa tacttcttat gcaattctac
      901 tcgaatatca agattatcat gacttttata ttgttcaatt actttatcaa tcattttaaa
      961 tgacctccac tctataattt ggcattatat cacaagaata aagatagtgt taaataagtt
     1021 atataaatgc aaaaaaggaa tattccgtta tagcagagtt gtaacacatt tctataaaga
     1081 aatttattcc tacgactcag tttggcatgc ttaacttcct aactcaaaaa caaagcatcg
     1141 attaatttat ccgttcttct tttgaaacag atttgaactg ataattgctc gttttaattt
     1201 aaaaagctct tttgagcaaa acttcatttt tttaagagtc caacaatttc tgtctatcgc
     1261 ttttctacta gcaaaaaacc taccttgagg caagttttca tttatatatc taatttcgta
     1321 acagtatagt aaaatgaaat aaggacagtc aaatcgattt ctaacaatgt tttagaagta
     1381 aaggtgtact attctagttt caatctacta taaatttgat atgagaatag tctttctcaa
     1441 catccttatc caacaagcat gctgtggcgt ccttcttaac ttaaaccagg tcaatattct
     1501 gggcttgggc tgcatagacg cagccacaat aacattgacg atagatatca tactcctcac
     1561 acatctctac tgaacgtttg tagccttgat ttttcttgaa atcgttggga agatagtggg
     1621 gcgtgtaaat tttttgcaca tcgattccga tgctattgat agtttgagaa ttcttatgag
     1681 gactgatggt caaggctgaa ccaaagtagt caaagcccaa gtccatagcc acttgcgctg
     1741 ttttatccag tcggtagtca aaacaaacct tgcaacggtc gccaccttcg ggctcctcct
     1801 ctagccccct aactagtttt cggtattaat tgggttcgta gggagcttct aggtactgaa
     1861 ccgtatttcc tgtctgctca ttaaaatcac taacaaattt cttggtgaca tagacccgct
     1921 tatggtattc tgccttggga tggatattag aattggcaaa atagatggtc acatctgcat
     1981 acttggtcaa atattctagt gtataggtac tacaaggggc acagcaaaca tgcacgagaa
     2041 tggttggccg ctactcattt ttttcccatg cttgtaccat tttctgcatg acacggtcat
     2101 aattaatctt ctgattgggg gtcatcttgc acagaatttc ttctacatcg atcatgttct
     2161 tctccttttt ctagtcttat tttatcatat aagttaggag agctcaaatc aatttagaag
     2221 tgaatattat aaaaagaagg gttagtcatt ccctcctttt gtgtttttta taagttgttt
     2281 tctatagaaa gcttacatca tcccgcccat catacttgga tccattgctg gagctggggc
     2341 tactggttct ggtttattgg ctacgactgc ttctgttgtc aaaatcaagc tggctacaga
     2401 tgctgcattt tgtagggctg aacgactcac tttaactgga tcaatgatac cttgatcaat
     2461 catgttaacc cactcgccag ttgctgcgtt gaatcctata ccaagctcag catttttcaa
     2521 acgatcgata acgatagatc cttcaaatcc tgcattgtga gcaatttgac gaacgggttc
     2581 ttccaaagca cggagaacaa tattacgtcc tgttgcttca tctcctgtca attccaaggt
     2641 agcaacagct ggaatcacat tggcaagagc tgttccacca cctgcaacaa taccttcttc
     2701 aacagctgca cgagtagcgt tgagggcatc ttcaatgcgg agtttcattt ctttcaactc
     2761 agtttcagtt gcggctccga ccttaataac cgctacacca cctgacaatt tggccaagcg
     2821 ttcttgcaat ttttcacggt caaattcaga agttgtagtt tcgatttgag acttgataac
     2881 cgcaacacgg tgagaaatcg cttcaggatt tcctgcacct tctacaataa ccgtgctatc
     2941 tttgtccacg gtcactctcg ctgcttgacc aagagcttca attgtcgcat ctttcaactc
     3001 aagaccaagg tcttctgtga taactgttcc gcctgttaag atggcgatat cttcaagcat
     3061 ggctttgcga cggtcaccaa aaccaggtgc cttgactgct actacgttga aggttccacg
     3121 aatcttgttc aaaacaagag ttggaagagc ctcgccatcc acatcatccg caataatcaa
     3181 gagtggacga ttgctttgga gaatgctttc caaaagtggc aagatttctt ggatattgga
     3241 aattttcttg tctgtaatca aaatgtacgg attttcaagg tcagccacca ttttttcgct
     3301 atcagtcacc atgtactgtg aaaggtaacc acggtcaaac tgcattcctt ctacgacttc
     3361 aagctctgtt tccataccac gtgactcttc gatggtgatg acaccgtctt tgccaacttt
     3421 ttccattgct tcagagatgt actcaccaac tttttcagaa cgagaagata cggctgcaac
     3481 ttgagcaata gcttctttat tggcaacagg gatggcgttg tttttcaaag cttcaactgc
     3541 tgcggcaacc gctgtttcaa tcccacgacg aataccgatt ggatttgcac ctgctgtgac
     3601 gtttttgatt ccttcacgga cgatagcttg ggtcaagact gttgcagtcg tagtcccgtc
     3661 acctgcgata tcattggttt tagaagctac ttctgatact aacttagcac ccatattttc
     3721 aaaatggtct tccaattcga tttctttggc aatggtcaca ccgtcattgg taatcaaggg
     3781 tgaaccgaat gacttttcaa gaacgacatt gcgacctttt ggtcccaagg ttactttaac
     3841 agtgtctgca aggatatcga caccacgaac catggctgaa cgggcatctg atgaaaattt
     3901 aatttctttt gacatactta ctttctcctt ctattcctca atgattgcca aaatgttagc
     3961 ttcgcctacg atgatgtact tttcatcgcc atctttgaca tcaagacctg cgtgggcttc
     4021 aactaagaca cgatctccag ttttaacact tggagcaacc aagtcaccgt tcaaggtacg
     4081 aacaccttgt ccagtagcca caacttgagc tgttttggtt ttttcttggg ctgagcctgc
     4141 aaggacaaag cccccaacgg tttgttcttt ttcttctatt tttaagacca cacggtcccc
     4201 taatggtttc aacatctgat ttcctccata atgagataga tattattagc actctttgaa
     4261 cttgagtgct aattcataat tctattgtat cacttggtca gaaatagtca agaaaaaagt
     4321 ctgactttct caagataaaa agcctgagac caactcagac tttttaatgt ttatactcaa
     4381 tgaaaatcaa agagcaaact aggaagctag ccgcaggctg ctcaaagcat tgctttgatg
     4441 ttgtggataa agctaacgtg gtttgaagag attttcgaag agtattaaaa tggcaattct
     4501 tcctcttcca agactaaatc tgccaaatct tggcctgcat tattttcacg catggcacgt
     4561 tgagcacgac tttccaagag ttggaatcct gtgacaagta cttcggtcac gtagttcatt
     4621 tggccatttt tctcaaagcg acgggtacgc aattctccat caacggaaat gagactacct
     4681 ttggttgcgt agcttgccaa agtttctgct agtctgcccc ataggaccat attgacaaaa
     4741 tcagcttcac gttcaccgtt ttggtctttg taacgacggt tcacagcgat agttgctcgc
     4801 gctaccgact tgtcattgtt ggttttgtgc aattctggtg tagacgttaa acgcccaatc
     4861 atgataactt tattatacat attttcttcc tcctacttat ctattcgtag gaaatcaaaa
     4921 aagttacaga aatttgtaac ttttcgagga aatttcttat tttttatgaa tcatgaaacc
     4981 tgtcgcctgt tgattggcca taatggtcat atctgtaatc tgaacacggc gaggctgact
     5041 ggtcacatag actactgtgt ctgcaatatc ctgagcttgc aaggcttcta ttccttggta
     5101 aacggacgca gcccgctctt tatcaccatg aaaacgaaca gttgagaaat ctgtttcgac
     5161 aatcccaggc tgaatggttg tcaccttgat atccgttgcg atggtatcaa ttcgcagtcc
     5221 atccgaaaag gtcttaaccg cagccttggt agctgagtaa acagcggcac cagcataggc
     5281 gtagattcct gcggttgacc ccatattgat aacgtgacct tgattgactt ttaccattgc
     5341 tggcaagaaa cagcgagtaa ccgccatcag acctttaaca ttggtatcca acatggtcaa
     5401 catatccaac tcctcatagt cttgataggg agccaagcca agagccagtc cggcgttgtt
     5461 gaccaagata tcaatcctcc ctatcgtttc tagaatatca gagcaaacag tcttcaccat
     5521 gaccatatcc gtcacatcta gtggaaaagt ccagacggtt tgatttggaa agcttactgc
     5581 aaactccgac ttgaggattt ctaatctgtc tatccgtcgt cctgttagaa cgacatcctc
     5641 accctgctcc agataagcac gcgcaatcgc ttcaccgatt cctgaggttg ctcccgtaat
     5701 cactacattt tttgccatct tatttccttc tatcagatgc tgacaagttc ctaggcagtc
     5761 cagtgtttcg ctgggtcgaa cggtgttccg acaacttggt cttctgataa ttcaagcacc
     5821 ccacgttttt gcggagcatt tggcaaatgc aattcacgag gactacacat catcccaaaa
     5881 ctcttttcac cacgaagttc gcctgggaaa atgaaattcc cttttggcat catggcacca
     5941 ggaagagcca caatggtttt caacccaaca cgcgcattag gtgctcctgc aacgatttgc
     6001 actatcttgt cacttgcgac tgcaacttgg cagatgttga ggtggtcact gtctggatga
     6061 gctaccatct cgacaatttc accaacaaca aacttaggtt ccttatcatt aacaatttct
     6121 tctgtaaaac cttccgcctg taattcttgg ttcaaacgag cgacttgctc atctgataaa
     6181 aagacttgac cgcgctctgc aatttcaaac aagctcgaaa cctcaaaaat gttccaagct
     6241 actgtttccc cattttcttt gaggaaaaca cgggctacct tgcctttgcg ttccacattc
     6301 agtttggcat ctccgctatt tttcacgatg accataagga catcaccgac atgttctttg
     6361 ttatacgtaa aaatcattgt ttcctttttc tcctatttca atcctgctaa aaaatcgtta
     6421 atttgctcct tacttttacg gtcgcgattg acaaaacgac caatttcctt gtccttttct
     6481 agaacaacaa ggctaggaat tccgtaaaca tcccagagtt tggccaaatc catatactga
     6541 tctcggtcca ttcgaataaa ggtgaactct ggattggtct cctcaatctc tggtaaggca
     6601 ggataaatat aacgacaatc gccacaccag tctgccacaa aaaggaagac cttcttgccc
     6661 gctttttcca ctaaagatgc taattcttct aaacttgctg gctgtatcat aagacttcct
     6721 cctcatagac taggtcttca ttttcataga caaaggtata atgacggcca tcctcaaaaa
     6781 taacgccacc aaccaagctc tccagactgc tttcgtaaac ttgaacatag agggtcgcaa
     6841 ttgcccccat gtcggaaaaa tggtctcgca caatctctgt caactcttcc tgagtcttca
     6901 tgagcttacg gtcatctgca acttttttcg tagcaagagc aaggcttccg atacctagca
     6961 gagccaagcc tgccatccac atttttttag ctttcatacc attcatttta acacaaaaaa
     7021 ggcttcagga caaatgagga agcagcagaa aagcaagtaa aaagcctctt cctttaagga
     7081 aaaggacttc ttatactaag agcaaactag gaagctagcc gcaggctgct caaaacacgg
     7141 ttttgaggtt gtagataagg cgacgctgac gtggtttgaa gagattttca aagagtatta
     7201 ttcttattgc caggcaccta agttgccaac gtagtaacca tcaggtgtgt aggtattgcg
     7261 aagcatctta cctgatgaag ccagataata ctacttgcca ttgtctttga cccaatcatt
     7321 cgcaatcatg gaaccagaag aactcacata ataccattct cccttgtcat aaacccaagt
     7381 actgactttc atggttcctg agcaattaaa ggcaaaaaaa ctgtccaata tcattcgttt
     7441 tttaaaagca tttgacacta catcatctac gctgtagtac atagatacat caaacgtaaa
     7501 agccaaaata tcgaaaaata tacaactttt aaaggcagca tttcattttt taaagtctaa
     7561 caaccataga actgaaatca gagcaaggca tcaatttcct actcttagta cgtctatttt
     7621 gatggtggaa gtgaagattt ttttatttaa cgtagacaat ttccaacttc ccaaaagcca
     7681 catctccacg gatagtcaag gttttgctgg ttggggctac aggagcgtca gccttagctg
     7741 caccaaagga ggtttctact ttcaaatcta cacgccagtg ttgtggaaca tagacggttg
     7801 catttccgaa ggccacttca atatttaaag ttgcaaaatc acctagcatc tctgcattat
     7861 catagtagat tttagcatcc ccaaaagcga cttccacttg gtcatctacg agatcttgat
     7921 cttgcttata gaaagtcccg ctaccaaaag cgacttcctt atccgtgacg actgtttttt
     7981 tcccattgta ccaccatttt ttttcattcc agaacttact tgaatgcgtc agataaccaa
     8041 caccaagtac caccaagatg ctagcccaaa taagagaatg attggtaact ggtaacaagt
     8101 cataagcgta atttgcaatg atgagcgcca gtaaacctgt aaaaactgcc gaagtgagat
     8161 gacgtctaag gatggactca atggacttat aagcaaaaaa aacaatacct agtaaaggcc
     8221 atattttacc atccaaagaa ggaattccaa aattcccttg cagcaagatc caagctgcta
     8281 aaaccaataa aacaatacca aatgctttct ttttcatgtt ttttacctca tgtttcttag
     8341 attttctttt aggagggatt ggtaatgccg tgagacatga acctccttgt gcgtctgata
     8401 aaaggaaatg gtgcccgttc ctgaaaagga cttgtccact gagtaaatct gacggatgtt
     8461 tgcgatcgtt gacttggaaa ctcgattaaa atagcgaggc aagatagact ccaactcata
     8521 gagcttgatg cgaacctcat aagcttcctt ctggttatga gcgtagatct tgctcccttc
     8581 tgtttcaaag aagagaattt ctgacaggtc tagataatat tcacctgtcc ccttgtaaaa
     8641 agtcaacctc ggagcctttg actcttgcaa gagccgttgc aagtctgcaa tttcatctgt
     8701 caaagtgggg gtcttgatga caatttcagt ctcctctaaa ttgccgtcaa tctcaattcg
     8761 taacttcatc acatctcctt tctgactcta ctatatcaaa gctaagttag gaatacaagg
     8821 gcaaaaaagc aagtggtcaa tttgaagcag taagtggttg taggactagc ttaacttaca
     8881 tgtcagaata ggaagaaaag gaatccccac accagaccac aagcatagcc aaccaagaca
     8941 tccttgggat aatgaacacc ccctaaaacc ctcaccaacc ccagcaaagc tgaaaagatc
     9001 aagcatacta agccaatagg tagactagca tgcagacagg ccatggagat gatagttgca
     9061 gaaaagacat ggcgactggg catcgaccgt cccgaactat ccttatcaag aaggggacag
     9121 atatcccaag tttcataagg tctcgggtga ttgattttct tacgaaacag ggacaaggcc
     9181 acaaaacctg atgcaggaat aagcacataa accccaactt gctgaccaag tcctagttgc
     9241 aggtaagtgg tgactagcaa gatcagatag accaggggca tggcgactgt catcaaacga
     9301 ttgaaactgc gtaataggaa taaaagaatt ggacgactag ttagtctgga gctgatattt
     9361 cgataccatt cttgataatt tttcatttat gcttctcata cttttctaga acttgttggg
     9421 atgttttccc cttggcaagc caatccacta gcttgtccaa gcgacgtatt tcctgcatca
     9481 gagaatcatc aatttcctca atacggacac cgcaaatctt ccctgtaatt gcaattcgtt
     9541 cagggacata atatggtgct tgtcgaaaaa aatctccgta agtaacatcc ctatccagac
     9601 aagcaagaac gtcactcact tcataccctg tcaaccaact ggtcacttgg tgaactgact
     9661 ctgcctttcc accctttcgc tcaacttttg caatcaaggc taagtagaca gcagcaaatt
     9721 tcatattgta taatttctga ctcatacttc tctctttcta tgtgtactag tataaataag
     9781 aaaaagaagg ccgtcaagcc ttcttttgat ttattcttct gcttcatctt ctgtaaattg
     9841 actattgtac aagtcagcgt agaatccacc ttgcaccatc aggtgaattt gatgaccaaa
     9901 acgcttaaag actaacatcg gtttacccat aatctccccc ttctaaataa aaatagttct
     9961 ctggagaata attaaatttc tatgagaact attttcttga ttaaaaaaat cccaagtgat
    10021 tttctcactt aggatcatgt tctataggtt aaattaaaac ccatctacgt tcgtataaat
    10081 cttttggacg tcttcgtcgt cttcaagaac gctgtaaagt ttttcaaagg tttcaaggtc
    10141 ttcgcctgac aattccactt ctgactgagg aatcatttcc aattcagtca cttggaattc
    10201 ttcaatacca gactcacgga gagcaacgat agccttgtga aggtcagttg gcgctgtgta
    10261 aactgtgatt gtaccttctt gtgcttctac gtcatccaca tccacatccg cttcgagcaa
    10321 ttgctcaaag actgcgtccg catcttcacc tccaaataca ataacacctt tgttgtcaaa
    10381 aaggtaagaa acagaacctg aagcgcccat gtttccgccg tttttaccaa aggctgcacg
    10441 gacattggct gctgtacggt taacgttaga agtcaaagta tccacaatta gcatagagcc
    10501 atttggccca aaaccttcgt aacgtccttc tgtaaaggtt tcgtctgtgt ttcctttggc
    10561 tttatcaatc gctttatcga taatgtgttt tggcacttgg gcttgtttag cacggtcgat
    10621 aacgaatttc aaagctgagt ttgattctgg atctggatca ccttttttag ctgctacata
    10681 gatttctaca ccaaattttg catatacttt agagttagct ccatctttag ccgttttctt
    10741 ggctacgata ttggcccatt tacgtcccat taggaatctc cttttttcac attttaatct
    10801 ttcttattat aacacaagtt tttttgattt tcactagagg aaatggattt tattagcaaa
    10861 tcaagctagg atagcacttt acctgctaag atggtcttgc ctttctatct ttatcaacag
    10921 acactcatcc acattcaaaa aacaaactag accattatct gcaaatagaa agtttcagcc
    10981 aagtttgaca aagtcagctc aaattactgt ttgaagtttg tagatataag cgacaaaaac
    11041 aatcatactg caccttttgt tgacagtcta ctccagacat atcatagttc aagtaaatac
    11101 tttgaaattc aacagttctt ataggcgcta ttgtattcta agaaatcaat agaagagttt
    11161 ctaagcaaac ctctaatact caataaaaat caaagagcaa actagaaagc tagcctcagg
    11221 ttgctcaaaa cactgttttg aggttgcgga tggggctgac atggtttgaa gagattttcg
    11281 aagagtataa tttacgtgtt cccaagatgg agaagttaga ctagtacact ggcacttcta
    11341 aaacattgct agcaattgat ttgttcatat ttaatttcat tttttccata aatgggtatt
    11401 agatataaac agcaaaatat ttccgatacg tgtcgttctt gaatttccaa tcatctaaaa
    11461 caagtaaagg ataatcaatc ccctgtatat caaggaattg gctacccttt ttactttttt
    11521 acacattctg tttgatagat tcattttaac atcacgagca tactccaatg gaaatcgcta
    11581 ggcaagagat aaactttcag atatccgcag agagatcatc gcctcttttt gtcgcaagca
    11641 ttctcctctc ctagtcattt tctaccttat cttctacctg aggatagaga gttgttcccc
    11701 aaatagaaat cgtccgctta cgcactagtg gcaaatcggt tttttcataa accgtacgcc
    11761 accattccca ggcaagcccg gtacactctc taattttgac agagagatta cgaacattcc
    11821 cttttaaagg aatactagtg gtaaagtgag ccgttaaatc ctgcccattt ctgtcccaag
    11881 ccttaggagt caagacttcc ttaccttgat gatcatagga taattcattc caagtaatat
    11941 aatattgggc aacataggca ccactatgat ccagcagtaa atctccgttt ctgtaagctg
    12001 taaccttagt ctcaacatag tctgtactat tttgaaaggt cgcaactaca ttgtcacgta
    12061 aaaaagaagt tgtataggaa atcggcaagc ctggatgatc tgctgtaaag cgactgcctt
    12121 cttgaatcaa gtcctctacc atatccacct tgcctgttac aactcgggca cccgaacttg
    12181 ggtcgccccc taaaataacc gccttcactt ctgtattgtc caaaatctgc ttccactctg
    12241 tctgaggagc taccttgact ccttttatca aagcttcaaa agcagcctct acttcatcac
    12301 tcttactcgt ggtttccaac ttgagataga cttggcgccc ataagcaaca ctcgaaatat
    12361 agaccaaagg acgctctgca gaaattcctc tctgttttaa atcctctacc gttacagtat
    12421 cttgaaacac atctcctgga tttttaacag cgtctacgct gactgtataa taaatctgct
    12481 taaaattaac aatctgaatc tgcttttcgc ctgaatggac agagttaaaa tcaatatcaa
    12541 gagaattccc tgtcttttca aagtcagaac caaacttgac cttgagttgt tccatgctgt
    12601 gagccgtgat tttttcatac tgcattctag ctgggacatt attgacctga ccataatctt
    12661 gatgccactt agccaacaaa tcgtttaccg ctccgcgaac acttgaattg ctgggatctt
    12721 ccacttggag aaagctatcg ctacttgcca aaccaggcaa atcaatacta taagtcatcg
    12781 gagcacgatc gaccgcaaga agagtgggat tattctctaa caaggtctca tccactacga
    12841 gaagtgctcc aggatagagg cgactgtcgt tggtagctgt tacagaaata tcacttgtat
    12901 ttgtcgacaa gctccgcttc tttctttcga taacaacaaa ctcatcgggt agctgattac
    12961 cctctttgat gaaacgattt tcaatacttt ctccctgatg ggtcaagagt ttctttttat
    13021 cgtaattcat agctagtata aagtcattta ctgctttatt tgccatcttc tacctcctaa
    13081 taagttcctg gattgagttg cataaactca gacttgttca gcgaaatcag ccgtggttgg
    13141 actaagtgat ccaaaatttc ctcgtacaat tcttctgaga cattgcgtcg ccgtctggct
    13201 agataagaag tcggaataac cgtattatcc aacataaata ccttatctaa gtcaatcaag
    13261 gttggtcttg taaaaggatt acgagctaga tccggctctt ctatcataaa gttcttgacc
    13321 aaacgtctgg tcaagagagc tggtttgaag gtctgatttt taaccaactc tttgttttta
    13381 gtcatgctgt tgtcaataca gatatacata tgattcttca cagccaaatc gctactaata
    13441 gtcggaaaag gcaaataaaa agctacaaca tctcctctct taatcaagca agagcacccc
    13501 cttttctcct aatgtaacat agacaggatt gaccaagtct tctgattgac tcagaatttc
    13561 caaagtttga gtttggcgcg ctgtcaattt agtagcatct tgtctcttca atacaaaatg
    13621 cttgtcgcca ataaccttga caatataatc cttctccaaa gctgactggt aaatccacat
    13681 cagatgttgt ctgtcctgag aactcaagcg agaaggattt tcaagcctcc cgatagtctg
    13741 ataaaaatca aaaacaggag ctaactcctg ccaatctgat tggctagttg tcaaggctag
    13801 aaaaagggct ttgcgagctg atacttcttg gttagccttg agagttactt tcccctccaa
    13861 gttttttaga aatcgggaaa ctccagaaag caaatttttc tctaactgcg agaaataaaa
    13921 acctttcgtt cccagacata agtctttcat gtcgctttct ctagcaaata agagctcaaa
    13981 catttgatag taaaagaaaa atatctggca ctgggtcgcg ctcatctttt ccttatcggc
    14041 ttcttttttt aaccagagca agggcgacag gtagctggat tgagacattt cctctacctc
    14101 ctactctttt ttaactggag catctgcact agctgccact tcttttgact ggatactttc
    14161 ccactggtta atctcctctg agataagacc ttcgcatgtc ttgacaaata gggcaaaagc
    14221 cttggtcttt cctgcatatt tctccgtttg gcattgatag aggaattttt ctttctccag
    14281 gagttgcgca gttttttggt aagaaatcca attttccttt gcattataca aattgataat
    14341 cccctcacac agcaagccga gactggataa ggcaaccgaa atcaaacggt agcgatcacc
    14401 tggcatagga atagcacaaa agacagctat gaggaaacct gccacgattt ctgttatttt
    14461 taatacctta tagcgtctac gatgttgaac gcttttcttt aaaaaatgag ctatctgtac
    14521 gtctaatcgc tctgtcaggt acatttcttc tggcgtcata ttcgtaactc ctttcattta
    14581 ctttgataac catagtataa catatttgaa tatcaaagta tagtaaaaac tggactataa
    14641 cttattagac ttcctgcgaa acaaaatatg gtatagtagt tctatgaatt atgaagcaag
    14701 taaacaacta actgatgcac gatttaagcg tcttgttagt gttcagcgta ccacttttga
    14761 agagatgtta gctgtattaa aaacagctta tcaaaaaagt cggacaagct ggtaaaatct
    14821 tggctgacag tggttatcaa gggctcatga agatatatcc tcaagcacaa actccacgta
    14881 aatccagcaa actcaagccg ctaacagttg aagataaagc ctataaccat gcgctatcta
    14941 aggagagaag caaggttgag aacatctttg ccaaagtaga aatgtttaaa atgttttcaa
    15001 caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgatt gctggtatta
    15061 tcaatcat
//
LOCUS       DAVKAU010000044        14047 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVKAU010000044 DAVKAU010000000
VERSION     DAVKAU010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14047
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.044"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            83..793
                     /locus_tag="VWX48_001581"
     CDS             83..793
                     /locus_tag="VWX48_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU9172177.1"
                     /translation="MRSMFAGAFLTFSTAAGAVGADLINKIAPGSGRFLFPFVFAWGL
                     AYIVFLNAELVTSNMMFLTAGSFLKKISWRKTAEILLYCTLFNLIGALIAGWGFAHSA
                     AYANLTHDSFISGVVEMKLGRSNELVLLEAILANIFVNIAILSFILVKDGGAKLWLVL
                     SAIYMFVFLTNEHIAANFASFAIVKFSVAADSIANFGVGNMLRHWGVTFIGNFIGGGL
                     LMGLPYAFLNKNEDTYVD"
     gene            941..2200
                     /locus_tag="VWX48_001582"
                     /pseudo
     CDS             941..2200
                     /locus_tag="VWX48_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2296..3570
                     /locus_tag="VWX48_001583"
     CDS             2296..3570
                     /locus_tag="VWX48_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU9172178.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIENFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKEHDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKVQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3580..4458
                     /gene="truB"
                     /locus_tag="VWX48_001584"
     CDS             3580..4458
                     /gene="truB"
                     /locus_tag="VWX48_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU9172179.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAADLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4699..5001
                     /locus_tag="VWX48_001585"
     CDS             4699..5001
                     /locus_tag="VWX48_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9172180.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMADLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5109..5747
                     /gene="udk"
                     /locus_tag="VWX48_001586"
     CDS             5109..5747
                     /gene="udk"
                     /locus_tag="VWX48_001586"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU9172181.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5875..7215
                     /locus_tag="VWX48_001587"
     CDS             5875..7215
                     /locus_tag="VWX48_001587"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU9172182.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSRIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7193..7405
                     /locus_tag="VWX48_001588"
     CDS             7193..7405
                     /locus_tag="VWX48_001588"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU9172183.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7402..8277
                     /locus_tag="VWX48_001589"
     CDS             7402..8277
                     /locus_tag="VWX48_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU9172184.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVGLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8270..9085
                     /locus_tag="VWX48_001590"
     CDS             8270..9085
                     /locus_tag="VWX48_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU9172185.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLVYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9078..9509
                     /locus_tag="VWX48_001591"
     CDS             9078..9509
                     /locus_tag="VWX48_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9172186.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9516..11183
                     /gene="recN"
                     /locus_tag="VWX48_001592"
     CDS             9516..11183
                     /gene="recN"
                     /locus_tag="VWX48_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU9172187.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11185..11913
                     /locus_tag="VWX48_001593"
     CDS             11185..11913
                     /locus_tag="VWX48_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU9172188.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            11992..13815
                     /gene="lepA"
                     /locus_tag="VWX48_001594"
     CDS             11992..13815
                     /gene="lepA"
                     /locus_tag="VWX48_001594"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU9172189.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(13896..>14047)
                     /locus_tag="VWX48_001595"
     CDS             complement(13896..>14047)
                     /locus_tag="VWX48_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172190.1"
                     /translation="KIKEQTRKLAAGCSKHSFEVVDETDEVSNHTYGKATLTWFEEIF
                     EEYKN"
BASE COUNT         4122 a         2575 c         3363 g         3987 t
ORIGIN      
        1 ttcttcagaa tttatttcaa agattgaatt tgcttgcaat aagaaagaaa gtctttatag
       61 tcaaagcaaa tttaagtatg cgattcgttc gatgttcgca ggtgcatttt taaccttcag
      121 tactgctgca ggtgcagttg gggctgactt gattaataaa attgcaccag gtagtggacg
      181 cttcctcttt ccattcgttt ttgcttgggg cttggcctac attgtttttt tgaatgccga
      241 gttggtcact tcaaacatga tgttcttgac tgctggtagt ttcttaaaaa aaatctcttg
      301 gagaaaaaca gctgagattt tactatactg taccttgttc aaccttatcg gagccttgat
      361 agcagggtgg ggctttgctc attcggcagc ctatgcgaat ctgacacacg atagtttcat
      421 ctcaggtgtt gttgagatga agttaggccg ctcaaatgaa ttggttttgc ttgaggcgat
      481 tttggcaaat attttcgtaa atattgcgat tctgtcattt attttggtca aagatggtgg
      541 tgccaaactt tggcttgtgt tgtcagctat ttacatgttt gtattcttaa caaacgagca
      601 cattgcggcg aactttgctt ctttcgcgat tgtgaaattc agtgttgctg cggattcaat
      661 tgccaacttc ggtgttggaa atatgcttcg ccactggggt gtgactttca tcggaaactt
      721 tatcggagga ggcctcttga tgggtcttcc atatgccttc ctcaataaaa acgaagatac
      781 ttatgtagat taagaaaatg agcacgattg agtcgtgctt ttttcatttt caaaataaga
      841 taatagctat ttcttatatc aaaatataga aaactgatat ttgtaaacta taactcaagg
      901 tgctacaata tccttaataa aataatatgg aggtcacctt atgactcgtg attttaaatt
      961 tgaaactcta caactacatg ctgttcaagt tgtggctcca gctactaagt ctcgtgcagt
     1021 gccgatttat caaacaacat tttttgtttt tgatgacacg taggaaggtg ccgatatgtt
     1081 tgccttgagg aaaccaggga acatttatac tcgtatcacc aatcctacaa cagctgccct
     1141 tgaaggtggt gttgaagcgc tagcaacagc atcaggtatg actgcagtga cttatacgat
     1201 tttggcgatt gcccatgctg gtgaccatgt agtggctgct tcgactattt acggtggaac
     1261 cttcaatctt ttgaaagaac cccttcctcg ttatggtatc acaacaacct ttgtcgatat
     1321 tgataatttg gaggaagtag aagcagctat caaagacaat accaagcttg tcttgattga
     1381 aaccttgggt aaccccttga ttaatattcc agacctggaa aaactggcag agattgctca
     1441 taaacatcaa atcccacttg tgtcagacaa tacttttgca acaccttatt tgattaacgt
     1501 cttctctcat ggcgttgaca ttgccattca ctctgcgact aagtttatcg gtgggcatgg
     1561 tacaactatt ggaggaataa ttgtcgatag tggtagtttt gactggacgg cttcagggaa
     1621 attccctcaa tttgttgacg agggtccaag ctgccacaat ttgagttata ctcgtgatgt
     1681 gggtgcagca gcctttatta tagctgttcg agttcaattg cttcgtgata caggtgcagc
     1741 cttgtcacca ttcaatgctt tcctcttgct acaaagactt gaaacccttt cacttcgtgt
     1801 ggaacgccat gtacaaaatg ctgagacaat tgttgatttt cttgtcaacc atcctaaggt
     1861 agaaaaggta aattatccaa aacttgcaga tagtccttat catgccttgg ctgagaaata
     1921 cttaccaaaa ggtgtgggct caatctttac cttccatgtc aaaggtgggg aggccgaagc
     1981 ccgcaaggtc attgataatt tggaaatctt ctcagacctt gctaacgtgg cagatgccaa
     2041 gtctcttgtt gttcatccag caacaaccac tcacggtcaa ttgtcagaca aagacctaga
     2101 agccgcaggt gttacaccaa accaaatccg cttgtcgatc ggacttgaaa atgtagagga
     2161 tttgattgaa gatttgcgct tggccttgga aaaaatttaa agtaaaagaa gataaacagt
     2221 ggttttcgac tcgctgtttt tgattttcct tcatgcatga tataatggtt acagaagtct
     2281 agaaagagga atgtaatgaa cgaaatcaaa tgtcccaact gtggggaagt ctttacagta
     2341 aatgaaagcc agtatgctga acttttgtcc caagtgagaa cggcagagtt tgataaggaa
     2401 ctacacgata ggatgaggca ggaactggcc ttggctgagc aaaaggctat gaatgagcaa
     2461 cagactaaac tggctcagaa ggatcaagaa attgcgcaat tacagagtca gatcgaaaac
     2521 tttgatacag aaaaagaatt ggccaagaaa gaagttgaac agacaagcca tcaggcctta
     2581 ttggctaagg acaaggaagt acaggctttg gagaaccaat tggccacttt gcgtttggag
     2641 catgaaaatc aactgcaaaa gaccctttct gacctagaaa aagaacatga tcaggtcaaa
     2701 aatcagctcc tcttgcaaga aaaggaaaat gagttgtctt tggcttctgt taagcaaaac
     2761 tatgaagccc agcttaaagc agctagtgaa caagtcgagt tttataagaa ttttaaggtt
     2821 caacaatcta caaaagcgat tggggaaagc ctagaacagt atgcagagag tgagtttaac
     2881 aaggttcgta gtttcgcctt tccaaatgct tactttgaga aggataacaa ggtctcttcg
     2941 cgtgggtcta aaggggactt tatcttccgt gagtgtgatg aaaatggagt tgaaatcatt
     3001 tctatcatgt ttgagatgaa aaacgaagcg gacggaacag agaagaagca caagaatgca
     3061 gatttttaca aggaattgga caaggaccgt cgggagaaga actgtgagta tgccgttttg
     3121 gtgaccatgc ttgaggctga taatgactac tttaacacag ggattgttga cgtcagtcac
     3181 gagtatgaaa aaatgtatgt tgttcgtcct caattcttta tccagttgat tggtctctta
     3241 cgtaatgcgg cgctaaattc cctaaaatac aagcaggagt tggccttggt tcgcgagcaa
     3301 aatattgaca ttacgcattt tgaggaagac ttggatgcct ttaagctagc ttttgctaag
     3361 aactataatt cagcttcgac taactttgga aaagctattg atgaaatcga caaggccatc
     3421 aaacgcatgg aagaggttaa gaaattcctg accacatctg aaaaccaact ccgtttagct
     3481 aacaacaaat tggaagatgt ctctgttaaa aaattgaccc ggaaaaatcc aacaatgaaa
     3541 gcgaagttcg aagcactgaa gggggagtag aaagcaaaaa tgaacggtat tatcaactta
     3601 aaaaaagaag caggaatgac ctcgcatgat gcggttttta aactgcgtaa gattttggga
     3661 accaagaaaa ttggtcatgg tggaaccttg gatccggatg tggtgggtgt tttgccgatt
     3721 gcggttggca aggcgacacg catggtcgag tttatgcagg acgaggggaa gatctatgag
     3781 ggggaaatta ctctgggcta ttccacgacg actgaggatg ctagtgggga agtggtcgca
     3841 gaaacccctg ttttgtctcc cttggatgaa aagcttgttg atgaagcgat tgctagcttg
     3901 actgggccta ttacccagat tccccctatg tattcggcag ttaaggttaa tggtcgcaag
     3961 ctctatgagt atgcgcgtgc tggtcaggaa gtggagcgtc cagaacgtca ggtgaccatt
     4021 tatcaatttg agcgaacaag tccgatttct tatgatggcc aacttgcccg attcactttt
     4081 cgtgtaaaat gcagtaaagg gacttacatc cgtactttgt cagttgattt gggtgaaaag
     4141 cttggttatg cggctcatat gtcccatttg actcgtacta gtgctgctga cttacaatta
     4201 gaagacgctc ttgccttgga ggaaattgct gaaaaagtag aggctgggca attagatttt
     4261 ctccatcctt tagagattgg gacaggtgac cttgtcaaag ttttcctaac tccagaagag
     4321 gctacagaag ttcgctttgg tcgttttatt gagctagacc aaacggataa agaactggct
     4381 gcctttgaag atgataaatt gttagccatt ctagaaaaac ggggcaatct ctataagcca
     4441 aggaaggttt ttagctagat cgtttaggaa taaaaatcgg gtgatagata acaattgctt
     4501 gataaaaccc catactaata gtagaatggt tttgggaatt ataatattcc aattgttgcg
     4561 agttgtaggt actcaaataa tctatataga aatttagagg tgtgaaatga agcaatttaa
     4621 aattctttca gataaatatt tagagtccat tacaggttct ggtgggaact taggcccagg
     4681 atttggtgtg ataattccat gatgcgaaat gagtttcgag aaagggtgga gcaacttctt
     4741 caacaaaaag aaataaatga aaatagtgag ttgagtcacc tgtttcgtct tgctatacaa
     4801 aatttagaca gaaatgaaaa acaccaatcg gtcatggccg atttgagtca agggttgtca
     4861 ctttacctca tgacgcatca ttaccaggca cctaagtctg tcattgattt tggtttatgg
     4921 attgccaaag ctcctagcca ggaaagaggg agactggctt tcttgcagat gcttgctcaa
     4981 accctacagg gctttcgtta aaactgtcga acatcagagg gaagactctg gtgttttttg
     5041 ctgatgagac tataaatttt gtaaaaaatg tgatagaata gacgacggat aaaataacgg
     5101 aggatagcat gcaaaataga ccaatcatta ttggagtgac aggtggttct ggtggtggta
     5161 aaaccagtgt ttcaagagcc attttatcgc attttcctga tgaaaagatt tccatgattg
     5221 agcatgattc atactacaag gatcagtctc atttgacctt tgaagagcgt gtcaaaacca
     5281 actatgacca tccttttgcc tttgatacag acttgatgat cgagcagatt aaggaattgt
     5341 tggcagggcg tccggtggac atcccgacct acgactatac agagcataca cggagtagca
     5401 agacctatcg tcaggagcct caagatgtct ttatcgttga gggcattttg gtcttggagg
     5461 acaagcgtct gcgcgatttg atggatatca agatttttgt ggatacggat gacgatgtgc
     5521 gtattattcg tcgtatcaag cgtgatatgg aggagcgtgg ccgtagcctt gatagcgtta
     5581 tcaaccagta cttaggtgtg gtcaaaccaa tgtaccacca gtttatcgag tcaactaagc
     5641 gttatgctga tatcgtcatt cctgaagggg ttagcaatac cgtggctatc gacctgttga
     5701 cgaccaagat tgcaaagatt ttggaagaag ctcgaaacag caaataatca catgtggagg
     5761 ccttgcctcc tttttctatt tttccctcat aatggtacat aaatggagat ttttaggcat
     5821 atttttggta taataatacc catgaaagag caagtaaatg aatagtaggt ggagatggaa
     5881 aagtatttat cggtaacaac tttgaccaag tatctgaaaa tgaaattcga taaagaccca
     5941 tacttggaac gggtctattt aactggtcaa gtttccaact ttcgtaaacg acctactcac
     6001 caatatttct ccctaaagga tgaccatgca gttattcaag cgaccatctg gtctaggatt
     6061 tatcagaaat tagggtttga cctggaagaa ggaatgaaga tcaatgtgat tgggcgtgta
     6121 caggtctatg aaccaagtgg tagctactcc atcatcattg aaaaagctga gcctgatggg
     6181 gttggggcgc ttgcgattca gtttgaacaa cttaagaaaa aattgacaga agaaggcctg
     6241 tttcaagaac gcttcaagca agctctgccc caattttcta agagaattgg tgtagtaacc
     6301 agccgtagtg gagctgttat tcgagatatt atcacgaccg tcagcaggcg attcccaggt
     6361 gttgacatcc ttctttatcc gaccaaggtt caaggtgaag gggctgcgga ggaaattgct
     6421 agaaatattg cgcgtgctaa tcaacgggac gatttggatt tgctcattat tggtcgtgga
     6481 ggtggttcta ttgaggatct ctgggccttt aacgaagaaa ttgtggtacg agctattttt
     6541 gaatctcgtt tgccagttat ctctagtgtg gggcatgaga cggatgtgac cttggcagat
     6601 tttgtggcag atcgacgcgc tgcaacgcca acagcggcgg ctgaactggc aacacctgtg
     6661 accaagttgg atgtattagc tcatttgcaa aatcaggaaa aacggatggt aacggcagtc
     6721 cgaaatgttc tatctaagaa acaagaggct ttgaaaaaat gcagtcagtc tgttatcttt
     6781 agacaacctg agcgcttgta tgacggttat ttgcaacgct tggaccaact gcaactgcgt
     6841 ttgaaacaaa gtttgcgaac tcggatttct gataacaaac aattagttca agcaagaact
     6901 catcaattag tacaattatc acctgttacc aaaatccaac gctatcaaga ccgtttagga
     6961 cagttggaca agctcttagg tagccaaatg gcgttagttt atgacgccaa ggttgctgag
     7021 gccaagcgac tttcggaagc tttgctcatg ttggatacta gccgaatcgt ggcgcgtggt
     7081 tatgctattg tcaaaaaaga agagtccgtt gtagattcgg ttgagagttt gaagaaaaaa
     7141 gaccaagtaa cgcttttgat gcgagatggt caagtagaat tagaggttaa agatgtcaaa
     7201 acaaaagaaa tttgaggaaa atctagcaga actggaaacc attgtccaaa gtttggaaaa
     7261 tggtgaaatt gctctggaag atgcgattac tgcctttcaa aagggcatgg tcttgtcaaa
     7321 agagctccaa gctacgctgg acaaggctga aaagaccttg gtcaaggtca tgcaagaaga
     7381 cggaacagaa agtgattttg aatgaaaaag caagaaaaat tagctcttgt cgagtcggct
     7441 ttggaagatt tttatggaga ccagcagttt gcctctagtt tacgggagtc tgttctctat
     7501 tctattcatg ctggtggcaa gcgtattcgg ccttttctct tgttagaagt tctggaagcc
     7561 ttgcaggtta ccatcaaacc tgctcacgcg caggtagcta ctgccttgga gatgattcat
     7621 acagggagct tgattcacga tgaccttcct gctatggatg atgacgatta tcgaagaggg
     7681 cggttaacca atcacaagaa attcggtgaa gctatggcca ttttggctgg agatgcctta
     7741 ttcttagacc catatgcctt gattgcgcag gcagatttgc caagtcagat caaggtgggc
     7801 ttgattgcca acttatccct tgcttcaggt agtctgggta tggtggcagg gcaagttttg
     7861 gatatggagg gcgaacacca gcacttgtct ctggaagaac ttcagactat tcatgccaat
     7921 aagactggga agttactagc ctatcccttc caagcggcag ctattatagc tgaattgtca
     7981 cctgaaatgc aggtgaagct gaaaactgtg ggtgaattga ttggacttgc ttttcaagtc
     8041 agagatgatg tactggatgt gacggctagt tttgaggaaa tcggcaagac acctcaaaag
     8101 gatctgcagg cagaaaaatc aacctatcct gccttgttgg gcttggaaga gtccattgcc
     8161 ttttgtaacc aaaccctgga tcaagctaat gaaaaattag aagaaattgc ccagcagctt
     8221 ccctttgaaa cagaatcgat tgtaagtgta gtagaaagtt tgagaatcaa tggctaagga
     8281 aagagtggat gtactagctt ataaacaggg gttgtttgaa acgagagagc aggccaagcg
     8341 aggtgtgatg gctggcctag tcgtagcagt ccttaatgga gaacggtttg acaagccagg
     8401 agagaaaatt ccagatgaca ccgaattaaa actcaagggg gagaaactca agtatgtcag
     8461 ccgtggtggt ttgaaactgg aaaaggcctt gcaggtcttt gatttgtcgg tggatggcgc
     8521 gactacgatt gatatcgggg cctctactgg aggttttacc gatgtcatgc tacagaatag
     8581 tgccaagttg gtctttgcag tcgatgttgg taccaatcag ttggcttgga aattacgcca
     8641 agacccacga gttgtcagca tggagcagtt caatttccgc tatgctgaaa agactgattt
     8701 cgagcaggag ccgagctttg ccagtattga tgtgagtttc atttccctta gtctgatttt
     8761 gccagccttg caccgtgtct tggctgatca aggtcaggtg gtagcacttg tcaaacctca
     8821 gtttgaggca ggacgtgagc agattgggaa aaatggaatt attcgagatg ctaagattca
     8881 tcagaatgtc cttgaatctg taacagctat ggcagtagag gcaggttttt cagtccttgg
     8941 cttggacttt tctcccatcc aaggtggaca tggaaatatt gaatttttag tgtatttgaa
     9001 aaaagaaaag tcagcaagca atcagattct tgctgagatt aaagaagcag tagagagggc
     9061 gcatagtcaa tttaaaaatg aataaaaaag agagacttga aaaaattaga agattggtga
     9121 cagattatca aatcggcacg caagaagaaa ttgtagaaca tttgaaagaa gcaggtatca
     9181 ctgccactca ggcgacggta tcccgagata tcaaagagtt aggtattgtc aaaattcctt
     9241 tgagagacaa cacctatgtc tacgaattgc caaaatcaat cgtaaaaagt ctgcaactgg
     9301 ctgaagacaa tatcgaatcg gctgaattga tggataagat gatcaatctc caagttattc
     9361 caggaaatac ggcttttgta aaagctcagt taatcgagac ttttgcagac aagattttta
     9421 gctgtttgac tgatgatagc tcgattttag tcattgccag aagtggaagt ctagcagagg
     9481 aaatctttga acaagtaaaa aattggtagg tctatatgtt acttgaaatt tcgataaaaa
     9541 actttgccat tattgaggct atttccctca attttgaaaa ggggatgact gtcctgactg
     9601 gtgaaacggg tgcagggaag tcgattatca ttgatgccat gaatatgatg ttgggagctc
     9661 gtgcgacgac agatgttatt cgtcatggtg caccaaaggc agagattgag gggcttttct
     9721 cagttgagaa tagtcgtctt ttacaggaaa tttttgatga gcaaggttta gaattaggtg
     9781 atgaaattat catccgtcgg gaaatcttgc aaaatggtcg tagtatcagc cgtgtaaatg
     9841 gtcagatggt taatctgtct gttttgcgag ctattgggca acatcttgta gatattcatg
     9901 gtcagcatga ccatgaggag ttaatgcgtc cccaactgca tatccagatg ttggatgaat
     9961 ttggtgatgc cgctttttgg gacttgaaag aaacctatca aacgagtttt gatgcctatc
    10021 ggaaaatgcg caagcaggtt ctggaagtca agaaaaacca acaggaacac aaggcacgta
    10081 tcgaaatgtt ggaatttcaa atggcagaga ttgaggcagc aaacttgcag gctggagaag
    10141 acttggctct caatcaagag cgagataaac tcctcaacca caaaaatatt gcggatacac
    10201 tgaccaatgc ctacagtatg ttggacaatg aagatttttc aagtctggcc aatgttcgtt
    10261 cagctatgaa tgacatggaa agtgtcgaag agtatgatcc tgaataccgt gaaatttcaa
    10321 gctctctgtc tgagacctac tatgttttag aagacattag caaacgtttg gaagctatca
    10381 ttgaggacct tgattttgat ggcaatcgcc tgatgcaggt tgagaatcgt ttggacctcc
    10441 ttcatactat tactcgtaag tatggtggga ctgttgatga tgttttgctt tattttgcca
    10501 agattacgga agaatacaat ctcttgacag gcaataatct ttcgtctgag gacatggaag
    10561 cagagcttaa gaagttggaa gtcaatcttg tcaatttggc aggtcaactt gcttctgctc
    10621 gtcataattt ggctcagcaa ctcgaagctg agattaaaca agaactgcaa gatctttata
    10681 tggaaaaagc ccagtttcag gttcgtttta gtaagggaaa attcagtcgt gagggaaata
    10741 aaatggttga gttttatatt tcaaccaacc ctggagaaga ctttaaaccc ttggttaagg
    10801 ttgcttctgg aggggaatta tctcgtctca tgttagccat taagtctgcc ttttcacgta
    10861 aagaaggcaa gactagcatt gtctttgatg aggtggatac gggagtttca ggtcgtgttg
    10921 ctcaagctat tgctcagaaa attcataaaa ttggtcagca tggtcaggtt ttggctatct
    10981 cccatttgcc acaagtaatt gcgattgcag attatcaatt ctttattgag aagattagta
    11041 atgaccattc aacggtttcg actgttcgtc tcttgacggt cgaagagcga gtggaggaag
    11101 ttgccaagat gttggcaggt gatgatgtga cagaagcagc cctgacgcaa gccagagaat
    11161 tgttgagaaa cagggagaaa taagatgaca gattattatg taattggaga tgttcacgga
    11221 aaagctggga tgctggaaga ccttctcaaa acctgggatg gtcagcccca gttgctcttt
    11281 ctaggtgatt tgattgacag aggtgaggat agtcaccgtg ttcttgaaat ggtcaaggac
    11341 ttggtggaca atcaaggggc tatctgtttg tccggaaacc acgagtatat gtttttgact
    11401 tggctagatg acccagaaga aagttatgac cattatagtc gcaatggtgg agatacaacc
    11461 attaactcta tcctaggtcg tcccttggat gcaccagttg atggagtaga agatgccaag
    11521 cgggttgccg ctgaagcgtc agacttggtc gaattcattc gtcaaatgcc atttgtagta
    11581 gagacagaca agtatatatt tgttcacgca ggtattgatt tgactttgga cgactggcat
    11641 gaaacaacag attataaaaa agtatggctt agaaaaccat tccacggagc tgaaaatcat
    11701 actggaaaaa ccattgtctt cggtcataca ccggtctatg gtttgttaca gcaagaacgc
    11761 ggtacatctg agctttggac tacagaagat ggcaagattg gaatggatgg aggagctgtt
    11821 tatggtggtg tccttcacgg gattgtcttt acagaccaag gaatgacaga acaccacttt
    11881 atcgaaaatg acggctttgt cgctgaagat tagtactcct agcagggtat ggtcttgtca
    11941 aaatatcaaa aacaatttat aataaataga taccctgaaa ggaagagaat catgaactta
    12001 gaagaattga aaaaacgaca ggggaagatc cgtaacttct ctattatcgc ccatattgac
    12061 cacgggaaat caactctagc agaccgcatt ttggaaaaaa cagagacggt ttcaagtcgt
    12121 gaaatgcagg cccagctttt ggatagcatg gatctagagc gggaacgtgg aattactatt
    12181 aagttgaatg ccatcgagtt gaattacact gcaaaagatg gggaaactta tattttccac
    12241 ttgattgaca caccagggca cgttgacttt acctatgaag tttcacgttc gctagctgcc
    12301 tgtgagggtg ctattttggt ggtcgatgcg gctcaaggaa ttgaggctca aactcttgcc
    12361 aacgtttatc tggctttgga taatgatttg gaaatcatgc ctatcattaa taaaattgac
    12421 ctgccggctg cagatccgga gcgcgtgcgt acagagattg aagatgtgat tggtttggat
    12481 gccagtgaag cagttttggc ttctgccaag gctggtattg ggattgaaga aatcctcgag
    12541 caaattgtag aaaaagtacc agcaccaacg ggtgatgtga cggcgccact taaggccttg
    12601 attttcgact ctgtttacga tgcttaccgt ggggttatcc tccaagtgcg tgtcatggac
    12661 ggagtggtca aacctggtga taagattcag ctcatgagca atagtaagac ctttgatgtg
    12721 gccgaagtcg gtatttttac accaaaagcg gttggtcgtg atttccttgc gactggtgat
    12781 gttggttaca ttgcggcgtc tatcaagacg gttcaggata ctcgtgtggg tgataccgtt
    12841 accttggcaa ccaatcctgc ggcagaacca ttacatggtt ataagcagat gaatcctatg
    12901 gtctttgcgg gtctctaccc aatcgaatca aacaagtaca atgacctgcg tgaagcgctt
    12961 gaaaaattgc aactgaatga tgctagtctt cagtttgaac cagaaacatc tcaggcactt
    13021 ggatttggtt tccgttgtgg atttcttgga cttctccata tggatgttat tcaggaacgt
    13081 ttagagcgtg agttcaatat tgacctcatc atgacagctc cgtctgttat ttacaaagtt
    13141 aatttgaccg acggtgagtc tatggatgtg tctaacccat ctgagtttcc agacccaact
    13201 aagattgcga ccattgaaga gccttatgtc aaggcgcaaa tcatggtacc acaggagttc
    13261 gtcggagcag taatggagct agctcagcgt aagcgtgggg actttgtgac tatggactat
    13321 attgatgata accgtgtcaa tgttatctat caaattcctc ttgctgaaat tgtctttgac
    13381 ttctttgata aacttaagtc ttcgacacgt ggttatgcaa gctttgacta cgaattgtca
    13441 gaatatcgcc catctaagct ggtgaaaatg gatatccttc tcaatggaga taaggtggat
    13501 gccctcagct ttatcgttca caaggacttt gcctacgaac gtgggaaact catcgttgat
    13561 aaactcaaga aaatcatccc tcgccaacaa tttgaagttc caatccaagc ggctattgga
    13621 cacaagattg tcgctcgtac tgatatcaag gcccttcgta agaacgtact tgctaaatgt
    13681 tatggtggtg acgtttctcg taagcgtaaa ctccttgaaa aacaaaaagc tggtaagaaa
    13741 cgcatgaaat ccatcggatc agttgaagtt ccgcaagaag ccttcctcag cgtcttgagt
    13801 atggatgaag aataagttat cagaaatgcc tttccttgtt cacaggaaat ttatataaaa
    13861 atcaatagta aagcaggctt agatggtctg cttttttagt ttttatactc ttcgaaaatc
    13921 tcttcaaacc acgtcagcgt cgccttaccg tatgtatggt tactgacttc gtcagtttca
    13981 tctacaacct caaaactgtg ttttgaacaa cctgcggcta gcttcctagt ttgctctttg
    14041 attttca
//
LOCUS       DAVKAU010000045        13870 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVKAU010000045 DAVKAU010000000
VERSION     DAVKAU010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13870
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.045"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..144
                     /locus_tag="VWX48_001596"
     CDS             <1..144
                     /locus_tag="VWX48_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein D"
                     /protein_id="HEU9172191.1"
                     /translation="YLEASGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANG
                     EWV"
     gene            545..1666
                     /gene="mnmA"
                     /locus_tag="VWX48_001597"
     CDS             545..1666
                     /gene="mnmA"
                     /locus_tag="VWX48_001597"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU9172192.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFT
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1807..2262
                     /locus_tag="VWX48_001598"
     CDS             1807..2262
                     /locus_tag="VWX48_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9172193.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2272..4185
                     /gene="mnmG"
                     /locus_tag="VWX48_001599"
     CDS             2272..4185
                     /gene="mnmG"
                     /locus_tag="VWX48_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU9172194.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4389..4466
                     /locus_tag="VWX48_001600"
                     /pseudo
     CDS             4389..4466
                     /locus_tag="VWX48_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4564..6243)
                     /locus_tag="VWX48_001601"
     CDS             complement(4564..6243)
                     /locus_tag="VWX48_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9172195.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6245..6478)
                     /locus_tag="VWX48_001602"
     CDS             complement(6245..6478)
                     /locus_tag="VWX48_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU9172196.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6758..6973
                     /locus_tag="VWX48_001603"
     CDS             6758..6973
                     /locus_tag="VWX48_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172197.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(7296..7448)
                     /gene="cibB"
                     /locus_tag="VWX48_001604"
     CDS             complement(7296..7448)
                     /gene="cibB"
                     /locus_tag="VWX48_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU9172198.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7450..7635)
                     /gene="cibA"
                     /locus_tag="VWX48_001605"
     CDS             complement(7450..7635)
                     /gene="cibA"
                     /locus_tag="VWX48_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU9172199.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7813..8496
                     /gene="tsaB"
                     /locus_tag="VWX48_001606"
     CDS             7813..8496
                     /gene="tsaB"
                     /locus_tag="VWX48_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU9172200.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8493..8930
                     /gene="rimI"
                     /locus_tag="VWX48_001607"
     CDS             8493..8930
                     /gene="rimI"
                     /locus_tag="VWX48_001607"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU9172201.1"
                     /translation="MIEIKRIQQQPDLAQAIYTVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8920..9930
                     /gene="tsaD"
                     /locus_tag="VWX48_001608"
     CDS             8920..9930
                     /gene="tsaD"
                     /locus_tag="VWX48_001608"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU9172202.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKTFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEEYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9970..11276)
                     /locus_tag="VWX48_001609"
                     /pseudo
     CDS             complement(9970..11276)
                     /locus_tag="VWX48_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11609..11903)
                     /locus_tag="VWX48_001610"
                     /pseudo
     CDS             complement(11609..11903)
                     /locus_tag="VWX48_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12010..12303)
                     /locus_tag="VWX48_001611"
                     /pseudo
     CDS             complement(12010..12303)
                     /locus_tag="VWX48_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12546..13720
                     /locus_tag="VWX48_001612"
                     /pseudo
     CDS             12546..13720
                     /locus_tag="VWX48_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13713..>13870
                     /locus_tag="VWX48_001613"
     CDS             13713..>13870
                     /locus_tag="VWX48_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9172203.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNL"
BASE COUNT         4067 a         2621 c         3188 g         3994 t
ORIGIN      
        1 tatcttgaag catcaggtgc tatgaaagca agccaatggt tcaaagtatc agataaatgg
       61 tactatgtca atggcttagg tgcccttgca gtcaacacaa ctgtagatgg ctataaagtc
      121 aatgccaatg gtgaatgggt ttaagccgat taaattaaat catgttaaga acatttgaca
      181 ttttaatttt gaaacaaaga taaggttcga ttgaatagat ttatgttcgt attctttagg
      241 tacctatctt atgatttcag gaaatgtcat taaaaaaacg actccttttc tctaacttga
      301 aaaatagatt agagaaaatg ggttgtttta tttattatag ttatttgaat gaagataaga
      361 agaaggtata ctcacatcat tcacataatc tgtatattga ctataagttt taaaaaacaa
      421 tttttaagct cttccttgtc ttctctaacc aagcgtgtta taatgaatac tgctcaagcg
      481 accttcaatc gtgaagcaca cacgaccttc aatcgtgaat aaacgaatag atgggagact
      541 taccatgagt gataactcta aaacacgtgt tgtcgtgggg atgagtggtg gtgttgattc
      601 gtcggtgacg gctcttttgc tcaaggagca gggctacgat gtgatcggta tcttcatgaa
      661 gaactgggat gacacagatg aaaacggcgt ctgtacggcg accgaagatt acaaggatgt
      721 ggttgcggtg gcagaccaga ttggcattcc ctactactct gtcaattttg aaaaagagta
      781 ctgggaccgc gtttttgagt atttcctagc ggaataccgt gcagggcgca cgccaaatcc
      841 ggacgttatg tgcaacaagg aaatcaagtt caaggccttt ttggactatg ccataacctt
      901 gggggcagac tatgtagcga ctgggcatta tgctcgagtg gcgcgtgatg aggacggcac
      961 tgttcacatg cttcgtggcg tggacaatgg caaggaccag acctatttcc tcagccaact
     1021 ttcgcaagaa caacttcaaa aaaccatgtt cccactagga catttggaaa agcctgaagt
     1081 tcgaaaacta gcagaagaag caggcctttc gactgctaag aagaaagact cgacagggat
     1141 ttgctttatc ggagaaaaga actttaaaaa cttcctcagc aactacctgc cagctcagcc
     1201 tggtcgcatg atgactgtgg atggtcgcga tatgggcgag catgcaggtc ttatgtacta
     1261 tacaatcggt cagcgtggcg gactcggtat cggtgggcaa cacggcggtg acaatgcccc
     1321 ttggttcgtt gtcggaaaag atctaagcaa gaatattctc tatgtaggac aaggattcta
     1381 ccatgattcg ctcatgtcaa ctagcctaga agccagtcaa gtccacttta ctcgtgaaat
     1441 gccagaagag tttacgctag aatgtacggc taaattccgt taccgtcagc ctgactctaa
     1501 ggtgaccgtc catgtcaaag gagacaaggc agaggttatc tttacagaac cgcaacgcgc
     1561 gattacacca ggacaggcag ttgtctttta cgatggcgaa gagtgtctag gtggcggttt
     1621 gattgacaat gcttaccgcg atggacaagt ttgtcagtac atttagattg acaaattttc
     1681 tcaatttgct acaataataa cagcaataga aatgatggtc aaagctcatg gatgttgcag
     1741 gcttttttgt cctgcacttc tttgtagttt tgactgtttt tgtgtcgttt aagggaaagg
     1801 acaagaatga ctcaacaaga ctttcggaca aaagtagaca atacggtttt tggtgttcgg
     1861 gcgacagctt tgattcttca aaatcgcaag cttctagtca ccaaagacaa gggcaagtat
     1921 tacactattg gaggtgcgat tcaagtcaat gaaagcacgg aagacgcggt agtccgtgaa
     1981 gtgaaggaag aactgggtgt caaagctcaa gctgggcagc tagcttttgt ggttgaaaat
     2041 cgttttgaac aagacggcgt ttcctatcac aatatcgagt ttcattatct ggtggatttg
     2101 cttgaagatg ccccgttgac catgcaggaa gatgagaaaa ggcagccctg tgagtggatt
     2161 gacttggata agcttgagga tatccagcta gttccagcct ttttaaaaac ggccctacca
     2221 gattgggaag gccaactaag acacattcat cttgaggaat aggagagaaa catgacttat
     2281 cattttactg aagaatacga tattattgta attggtgcgg gacacgctgg ggttgaggct
     2341 tccttggccg ctagccgtat gggctgtaag gtcctgcttg cgaccatcaa tattgaaatg
     2401 ctggctttca tgccttgtaa tccctctatc ggtggttctg ccaaggggat tgtcgtgcgt
     2461 gaagtcgatg ccctcggtgg cgagatggcc aagactattg acaagactta catccagatg
     2521 aagatgctca acacagggaa ggggccagct gtccgtgctc ttcgtgcgca ggctgacaag
     2581 gaactttact ctaaggagat gcgcaagaca gttgaaaatc aagaaaatct gacccttcgt
     2641 caaaccatga ttgatgagat tttggtggaa gatggcaagg ttgtcggtgt gcgtacagcc
     2701 acccatcaag aatatgctgc taaggctgtt attgtgacga cagggactgc tctccgtggg
     2761 gaaattatca tcggagacct caagtactca tcaggtccta accacagctt ggcttctatt
     2821 aacctagctg acaatctcaa ggaactgggc ctcgaaatcg gtcgtttcaa gacaggaacc
     2881 cctccacgtg tcaaggcctc ttctatcaac tacgacgtga cagaaatcca accaggagat
     2941 gaagcaccta atcacttctc atacacttca cgtgatgagg attatgtcaa ggaccaagtg
     3001 ccatgctggt tgacctacac caatggtacc agtcatgaga ttatccaaaa caacctccac
     3061 cgtgcgccta tgtttacagg tgtggtcaag ggagtggggc ctcgttactg tccgtcgatt
     3121 gaagacaaga ttgtgcgctt tgcggacaag gaacgtcacc aactcttcct tgagccagaa
     3181 gggcgcaata ctgaggaagt ctatgtgcaa ggactttcaa ccagtctgcc tgaggatgtc
     3241 cagcgtgact tggttcattc catcaaaggt ttggaaaatg cagagatgat gcggacaggt
     3301 tatgctattg agtatgatat ggtcttgcct catcagttgc gtgcgacttt ggaaaccaag
     3361 aaaatctcag gacttttcac tgctggtcag acaaatggaa catcaggtta cgaagaggca
     3421 gcaggccaag ggattattgc aggtatcaat gcggctctga aaatccaagg taaacctgag
     3481 ttgattctaa aacgaagtga cggttatatc ggggtgatga tcgacgactt ggtgaccaag
     3541 ggaaccattg aaccttaccg tctcttgacc agtcgtgctg aataccgtct cattcttcgt
     3601 catgacaatg ctgatatgcg cttgactgag atgggacgcg agattggcct tgtggatgat
     3661 gaacgctggg ctcgttttga aatcaagaaa aatcaatttg ataatgagat gaaacgccta
     3721 gacagtatca aactcaagcc agtcaaggaa accaatgcta aggttgagga aatgggcttc
     3781 aagccgttga cagatgcggt gacagccaag gaattccttc gccgtccaga agtttcttac
     3841 caagatgtgg tggccttcat cggaccagct gcagaagact tggatgacaa gattatcgaa
     3901 ttgattgaaa cagaaatcaa gtacgaaggt tacatctcaa aagccatgga tcaggttgct
     3961 aagatgaagc gcatggaaga aaaacgtatt ccagccaata tcgactggga tgacattgat
     4021 tctatcgcaa ccgaagcccg tcagaagttc aaactcatca atccagaaac catcggccaa
     4081 gccagccgta tttcgggagt aaacccagca gatatttcta ttttgatggt gtatctggaa
     4141 ggtaaaaatc gtagtatttc taaaactctt caaaaatcaa aatgatacgt cgtaggcttc
     4201 ttacgaatga gttcaaagct tggctttgat tcatctccaa cctcccatag ttccccgaac
     4261 tatgggagct aactcaagtt atgctttcgc ttagccttct agtctgattt tcattgagtt
     4321 ttaatctcaa aagaaagcat agagaaaaac agctccgaag acggggctgt tttgttgact
     4381 tgtactcaat gaaaatcaaa gagcaaacta ggaagctagc cgtaggttgc tcaaagcact
     4441 gctttgaggt tgtagataga actgacgaag tcagctcaaa acacagtttt gaggttgtgg
     4501 atagaattga cgaagtcagt aacatatata cggcaaggcg aagctgacgt ggtttgaaga
     4561 gtattattct tcatctggtg tgaggatcat cgggatgatg atcggttcac gttcggtatt
     4621 ttcatagagg aaggggcgaa tagcgttgac aatggcacca ttgacagatt gcacgctagc
     4681 atccttattt ttcagtgcga tacgaatggc attgaagagg atacgctggc tttggcgaat
     4741 caagtcgcca gactctctca tgtagacaaa gcctcggctg aggatgtctg gaccagatag
     4801 aatcatctgc gatttgaagt caacagttgc aactgccaga acgacaccgt cttcagatag
     4861 atcgcgacga tctttgagga cagctgcgcc aatttcaccg atacgatttc catcgacata
     4921 gatatcttgg gcgttgaaat gacctgcgat acgagctgag tcagcagtaa gggcaagcac
     4981 atcgccattg ctcatgataa agatattgtc cttctcaaca ccagtatcca ctgctagtcc
     5041 agcgtggact ttttgcatgc ggtattcacc gtggacaggc atgaagtatt ttggcttaat
     5101 caagcagagc atgagttttt gctcttgctg accaccgtgt ccagatgtat ggatattgtt
     5161 cactttaccg tggataactt cgacaccagc ttcagaaatg atgttaatca gcttgttgac
     5221 gctagtagtg tttccaggga tgggactaga agagaagata acggtatcac ctggttgtaa
     5281 ttgtacttga cggtgggttc cgttggcgat acgagagagg gctgccatag gctcaccctg
     5341 actacctgta cagaggataa gaacttctcc tgcaggataa tctttgattt catttggctc
     5401 gataaaggtt cccttaggag ctttgatgta gccaagatcg attccgttga caatggcctt
     5461 ttccatagaa cgaccaaaga ccgcaatctt gcgtccagtc ttaacagcag cttctgttgc
     5521 ctgctggaga cggaagatat ttgaggcaaa ggatgcaaag atgatacgtc cttcaatacc
     5581 ttggataatc ttcatgatgg actggccgac aaccttttca gagttggtaa aggttggtac
     5641 ttccgcattt gtcgagtcag acaggagaca gagcacgcct tcttcaccaa gcgcagccat
     5701 acggtgcaag tctgcaggtt caccaactgg agtaaagtcg aacttaaagt cacccgtaca
     5761 gacgattttc ccttgaggag tatgaatgac aatccccaaa ggctctggaa tagagtgagt
     5821 cgttctaaag aaagttgcct tgagattttt aaaggtcaac tcggtgttgt ggttgatttc
     5881 gtaaagtttg gcgttgcgca agaggccgtg ctcttcgagt tttccacgga tcaaagccag
     5941 cgcaagcggt ccagcgtaga tcgggacatt tgcttgcttg agcaggaatg gaatcccacc
     6001 gatgtggtcc tcgtgtccgt gcgtaatcaa aacagccttg acgcggtcga tattgtccac
     6061 gatgtaagaa taatcaggaa tgacatagtc gataccaagc aagtcatctt ctgggaattt
     6121 aatcccagca tcgacgatga taatctcatc ttggtattca attccgtaag tgtttttccc
     6181 gatttctccc agaccaccga tggcaaaaac accaacttct tcaggtttaa gagtgtaggc
     6241 catattagaa ctccgtaatt tcgaaggcgc cagtttcttt ttcgtaatcg agcaatttgt
     6301 cagacaagag ttcgatatat tcgatattgt actctgggcg attttcttcg acaagttggc
     6361 gagcagtgat acggccctca agttctgagc tggtatcgat atctaagtaa agcgcgcgtg
     6421 ttgtttcacg gcgtgggcta cgttcttttg tttcttgata aaaaactttg taaatcatat
     6481 agttcctttc tatttacagg tcagcttatt ccaaactttt agcagatatt tgcttgattt
     6541 cattccattt tgtgtctaga ttgaccttga ttcgttacaa ttatttcaat tataccacaa
     6601 aatgaaaaat tagtaaaaga cggaaacgag aaagttaggg gacgatttct ttggtaagcg
     6661 tttgcaaaaa caaagaaaat gtattatgtt gataacggaa gtgaaattta ttgcttgtca
     6721 taattccata tagattttaa gtcaaggagg ttgccctatg tataacttat ttgcttttgc
     6781 tatcggagct cgcttggtag cttttattgt ttttgttgct tgcgtttatg cggggaatct
     6841 tctatttgcc aaactggaac gacgacaaac caagttcttg tggaaaatga cctttgtgac
     6901 tctctactcg ctttttctcc tcctcgtgac ctatgtcgtt tggtttgtat tttactttga
     6961 attaaatgct tagatgccct gcttatgctg gggttttttg tttggggatg tagagatagt
     7021 agatttacga cacgaaaatt ccaccccatc tatcaagatg aggtggtctt tgcatttttc
     7081 taacatgaca tgacaatgga attttcaaag cttattattt ttatgggagt cattgttctg
     7141 atcaaaaata gagttgaagc ataaaaataa aacaatacaa acagataaat cgaatggtaa
     7201 agggatggta gtaatgttca aatcattgag aatgctgagc aaactgtaag agatgaagac
     7261 aataaaattt atccttctaa aaatgtgttt cttatctagc atgacttacc aaacttttta
     7321 cgaaggtctt ttccaatggt ataacctgcc ataaataaag cgataccaac accgacacca
     7381 aagccaccct tgatttcttg caattcctta ttagaaattt cacgataatt gttcaaatct
     7441 ttcatcatat taatctcctc ctaaaaaata accagctgcc aaaccagaac ctataagtgc
     7501 tgttccacct gcaatagcct tccaagatac tgctactcca aagataacca agggagcgag
     7561 accgccatca atatctgata attcattttc agataaggat aaaaattgat tgtcaagaat
     7621 gtcaaaattt gtcattgaac tttcctcctt ttttcttgtt cacttttata ttcggaaaag
     7681 aaaaggaaaa gtgagcattt ttttaaatta tttttagtta agtgagggca ctcttgtctg
     7741 ggggcaaaga aaattcccat gtgccagctt ttgtagtata atagtaagca gacaaaaaga
     7801 taggaatgtg ttatgaaagt attagctttt gatacgtcca gcaaggctct ttctctggct
     7861 attttagagg ataagcaggt tcttgccgag acgacgatta atattaagaa aaatcacagt
     7921 attactctta tgcctgccat cgattttttg atggcaagtt tggattggac acccaaggat
     7981 ttggaccgaa tcgtggtagc tgaagggccg ggtagctata caggcttgcg aattgcggta
     8041 gcaactgcta agaccttagc ttacaccctg aacatcgagt tggttggtat gtcgagtctc
     8101 ttggctctgg tgccccacca acaagaaggt ttgtttgtcc ccttgatgga tgcgcgtcgc
     8161 aataatgttt atgcaggatt ttatgaaaat gccaaacctg tcatggcaga agcgcaccta
     8221 tcttttgaag aggtgctaga aaaagtcaag ggtactagtc aggtaacctt tgtcggagaa
     8281 gttggcccct ttgttgagca gattcaaaaa cacttgccaa ggactgatta caaagaaaca
     8341 ttgcccaatg cagctaatct agctcttttg gcctgggaca aggaagcaga ctccttgcat
     8401 gattttgtgc cgaattacct caaacgagtc gaggctgagg aaaactggct caagaaccat
     8461 accgagtctg gcgagtctta cattaaacgc ctatgataga aatcaagcga attcaacaac
     8521 agcctgacct agctcaagcc atctacactg ttatggcagc tgtttaccta gtcagtcctt
     8581 ggactctgga gcaaatccaa gcagatctgt cccaagacca gacttggtat gcattggctt
     8641 atgatggggc agaagtgatt ggatttctag ctgtgcagga gaatcttttt gaagcagaag
     8701 tcctgcaaat cgctgtcaaa ggagcttatc agggtcaggg aattgcgtca gccttgtttg
     8761 ctcaattgcc gacagacaag gaaattttcc tcgaagtcag acagtcaaat caacgagcgc
     8821 aagcatttta caagaaagaa aagatggcag ttatcgctga gcgaaaggcc tactaccatg
     8881 acccagtcga ggacgccatt atcatgaaga gagaaataga tgaaggatag atatatttta
     8941 gcatttgaga catcctgtga tgagaccagt gtcgccgtct tgaaaaacga cgatgagctc
     9001 ttgtccaatg tcattgctag tcaaattgag agtcacaaac gttttggtgg cgtagtgccc
     9061 gaagtagcca gtcgtcacca tgtcgaggtc attacagcct gtatcgagga ggcattggca
     9121 gaagcaggga ttaccgaaga ggacgtgaca gctgttgcgg ttacctatgg accgggctta
     9181 gtcggagcct tgctagttgg cttgtcagct gccaagacct ttgcttgggc tcacggactt
     9241 ccgctgatcc ctgttaatca catggctggg cacctcatgg ccgctcagag tgtggagcct
     9301 ttggagtttc ctttgttggc actcttggtc agcggtggcc acacagagtt ggtctatgtt
     9361 tctgaggctg gcgattacaa gattgttggg gagacacgag atgacgcggt tggcgaggcc
     9421 tatgataagg tcggccgtgt catgggcttg acctatcctg caggtcgtga gattgacgag
     9481 ctggctcatc aggggcagga tatttatgat ttcccccgtg ccatgattaa ggaagataat
     9541 ctggagtttt cattctctgg tttgaagtca gcctttatca atcttcatca caatgccgag
     9601 caaaagggag aaagcctgtc tacagaagat ttgtgtgctt ccttccaagc agcagttatg
     9661 gacattctca tggcaaaaac caagaaggct ttggaggaat atcctgttaa aaccctagtt
     9721 gtggcaggtg gtgtggcagc caataaaggt ctcagagaac gcttagcagc cgaaatcaca
     9781 gatgtcaagg ttatcatccc ccctctgcga ctctgcggag acaatgcagg tatgattgcc
     9841 tatgccagcg tcagcgagtg gaacaaagaa aacttcgcag gctgggacct caatgccaaa
     9901 ccaagtcttg cctttgatac catggaataa agagtggctc tttgtcaagt gtagtgggta
     9961 ggcgaaaagt tacaatctgg agagtacgaa attcgtactc tcttttttga tgttcaaagt
    10021 catcaaaatc cgttttttaa aattgttaaa gttccggaaa ccaaaggctt tgcgcttgat
    10081 aaccttaatc aaattattgg tcgcttcaag tttagcgttg gaataaggca gcttaagtgc
    10141 gttgataatc ttatctctat cccttaaaaa agtccaaaag accgtttgaa aaagcggatg
    10201 aaccgttggc agttcttgct caatcaatcc aaagaaatgg tcggcattct tctcttgaaa
    10261 atgaaagagc aggagttgat agagttcgta gtaaacctgt aatccctcag agtaagaaag
    10321 cagcttatct cgtacttccc gatgggttaa gtgcattcga aacgtgggct gatagaatcg
    10381 tttctgacag agcttgaagc tatcctggtg tagtaaatca gtccagtgga ctgatttagc
    10441 ccgagcctag aaacgaaaaa gcgagggttc caaaagcgct tgagcgcccg atactccaag
    10501 gattttcggt caaattggtt catgatttgg attcgtactc ggttcatagc tcggctcaga
    10561 tgttggacaa tgtggaagcg gtcaagaaca atcttcgcct ttggaaagag ctgcttagcg
    10621 agccgataat aagggctgta catgtccatg gtgatgacct cgaccagctc ccgaacctct
    10681 ctctgatagc gttggaaatg gtttcgaatc accgcatgag ttcgcccgtc taaaattgcg
    10741 aggatggatt tggactcaaa atcttgggca atgaagctca ttttgctctt tttgaagcta
    10801 tactcatccc aactcataac ttttggcaac ttggtccaat cggtttcaaa cttaaattcc
    10861 ctcagttttc ggatgacggt ggaagttgag accgccaatc tgtgggcaat ctcagtcata
    10921 gactgctttt caaggaggag ctgagcgatt ttttgtctca ccatgttgga aatctggcaa
    10981 tttttcttga caatggatgt ttgagaaacg accaccttaa ggcaattctt gcactgaaag
    11041 cggcgctttt tgagatgcag taccgtgggt aaaccctgac agtcgagaag cggaatttta
    11101 gaggctttct ggaagtcgta tttgatcatc ttcccttgac aatgaggaca aggaggagcg
    11161 ggggaatcca actttgcctg aacgactaga tgggtttggt atttcagaac agacaagatt
    11221 ttgatatttt tgtcttccaa tccgagcaaa tctgtggtat tcttaagttg ttccatatga
    11281 accctttcta atgagttagt tagacgcttt tcattatagg tcatatgggg ctttttttct
    11341 acaagaaacg accctataat tcctggggtg ggattaccca ctacagaaat tatagagcca
    11401 aagcattcca aagtcttgtc tgactctgga atgttttctg ttcacagttg ttttgtaact
    11461 gcctaataag taaccgcgct ataacgaggt atctaccgag attgtcaatt ctccagtata
    11521 ctgttataaa aaacaaaact ggaggatttt tttatgtccc cccatcgtcc catcgactgt
    11581 tccgtagctg cccaataacg gagtataatc atctgaaaca agaataggac aaaagtgcct
    11641 caagaaaagc atcgtaattt gacaatatta ttctgagatg tttttgatgt aagcccatat
    11701 tttctcaatg ggattatact cgggtgaata ggtaggaagt ggtaacagtc tatgccctgc
    11761 tccttacaca tgttcattct gtgaaacctt gcattgtcca taatgataag ggatggtgta
    11821 tctaaagtag gtagtaagaa tttttggaag caagcttcga aaaagtcact cgtcatcgta
    11881 tctttatagg tcatcggagc catagtatat tgaaacaaaa aagggcatta gtacttctat
    11941 aacagtatcg caatctctgg tgtgcgttgt ctcgatctta attcaaataa ttatatcttc
    12001 ttccagagag actaactgcc tgctcaaggc tcgatcatat tcgagataaa aataggtctc
    12061 aacccctgtc tcataaatat aaataggagt caggtagctt aagtgattca attctttaag
    12121 gaaccgattt actttttctg ggtcttgttc gcagtaggta cggctctttt ttagactata
    12181 tcccatagcc tttagagcgt aatgaatagt tgttggagga cagttgaatt cagcagctat
    12241 ttcagtcaaa taagcatcgg gatgagtttc aatatagatc tttaatttat ctctatcaac
    12301 tttttcaatt aatagtggaa gttttcttaa agttagtgtg ttgaaacgtt tttatacagt
    12361 gctaaaattt gaagtgtagt gcagatgtat ttgtaatagt attatagcaa ttctttggag
    12421 aaggtcgaga caagagaaaa taggtatctt tgagatataa gcatgattta ctataaaatt
    12481 attgagttat tcataaaaat ttttctatca aatatcataa tgcgtcgttt aaggagatgg
    12541 ttacaatgca atatagttgt ggaaaaataa atattaatat ccctgatgga tatggagaca
    12601 ttaaggatat agtgttttcg gctcatatta tagttaggta taataatgga cattgtggag
    12661 gtatagatcc gcatataatt ggactttgta aaaagcagat cagaaggatg tctctatatc
    12721 ctattttgat aatcgtatct agagattcaa aggttattga tgattataaa aatttagata
    12781 ttgcctatgt tgattgtact caatgttcaa ataattttga aactgcctta cacgttaaaa
    12841 atattttaaa attattaaaa atccaactta tacactgtca tggctactca actaattatt
    12901 ttttatatat gttaaaaaaa cttgacaaga atggatttgg aaaggttaag acagtgataa
    12961 catgccatgg atgggttgaa tataacttaa aaaagaaatt cttgacttat tttgattttt
    13021 ggacatattc tatgggagat gcttttattt gtgtatctga aactatgaaa aaaagattgg
    13081 agagtataat aaaaaaataa gaagatagtt gcaataaata acggaattaa tgtatcaaat
    13141 agcgatttag atgtagtagg tgttcaagac tttaaaaaag aattttgtat tccaaataac
    13201 aaaaaaatca tttgttatgt tggaaggttg gatccagaaa aaaggccgga tagattcctt
    13261 gaatttgcag aaaaattatt tttagtcaga gaagatgtga tttttattat ggctggaaat
    13321 ggtagtatgt gggctgcttt gaaagaaaaa atttgccatt tgaaatgtag agataatttc
    13381 aggttacttg gtgaaatcta tccagctact atagtttacc aaatatcgga tttattgtat
    13441 attccttctg atacagaagg aatacctatg tgtgttttag agtcaatgtc acaaggaact
    13501 ccggttttag ctagtaatgt tggcgggtta agtgaaatta ttgaacatag ggttgatgga
    13561 tttttatttg agaaggaaga tgttgaggga gtgtgtgctt gtgctaattt tttactcaat
    13621 gattctgagt atttgaaata tataggtgag aatagtaaat caaaaataag aaaacatgag
    13681 agtatatgat gaattattag agaagagtag tcatggatag gaatatagat caagaattag
    13741 taagtattat aataccaaca cataataggt atgaatctct gattagagct gtgaaaagtt
    13801 gtttacatca aagttataaa aatatcgaag ttataattat tgatgataat tatagtaatg
    13861 taaatttaag
//
LOCUS       DAVKAU010000046        13830 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVKAU010000046 DAVKAU010000000
VERSION     DAVKAU010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.046"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..309
                     /locus_tag="VWX48_001614"
     CDS             <1..309
                     /locus_tag="VWX48_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU9172204.1"
                     /translation="ENTILHSDQGWQYQHDSYHQFLEGKGIQASMSRKGNSQDNGMME
                     SFFGILKSEMFYGYEKSFQSLKQLEQAIIDYIDYYNNKRIKVKLKGLSPVQYRTKSFG
                     "
     gene            complement(383..913)
                     /locus_tag="VWX48_001615"
     CDS             complement(383..913)
                     /locus_tag="VWX48_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEU9172205.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPNWKMDLFSEEEKRNYFQTTCEIS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(907..1374)
                     /locus_tag="VWX48_001616"
                     /pseudo
     CDS             complement(907..1374)
                     /locus_tag="VWX48_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1924..2601
                     /locus_tag="VWX48_001617"
     CDS             1924..2601
                     /locus_tag="VWX48_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU9172206.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQVKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVETGEM
                     ELSARDTRFGPFLSREISPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2588..3385
                     /locus_tag="VWX48_001618"
     CDS             2588..3385
                     /locus_tag="VWX48_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU9172207.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3402..4505
                     /locus_tag="VWX48_001619"
     CDS             3402..4505
                     /locus_tag="VWX48_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU9172208.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            4512..4658
                     /locus_tag="VWX48_001620"
     CDS             4512..4658
                     /locus_tag="VWX48_001620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172209.1"
                     /translation="MKIKEQTRKLAAGYSKRCFEVVDRTDEVSNHTHGKATLTWFELD
                     FRRV"
     gene            4761..5780
                     /gene="galE"
                     /locus_tag="VWX48_001621"
     CDS             4761..5780
                     /gene="galE"
                     /locus_tag="VWX48_001621"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9172210.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEELTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPYTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5782..6735
                     /locus_tag="VWX48_001622"
     CDS             5782..6735
                     /locus_tag="VWX48_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9172211.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6797..7003)
                     /locus_tag="VWX48_001623"
     CDS             complement(6797..7003)
                     /locus_tag="VWX48_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU9172212.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7055..7531
                     /locus_tag="VWX48_001624"
     CDS             7055..7531
                     /locus_tag="VWX48_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU9172213.1"
                     /translation="MAKEPWQEDIYDQEESRAERRPRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EGAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7540..8211
                     /locus_tag="VWX48_001625"
     CDS             7540..8211
                     /locus_tag="VWX48_001625"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU9172214.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHSISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVRKKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8342..8680
                     /locus_tag="VWX48_001626"
     CDS             8342..8680
                     /locus_tag="VWX48_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU9172215.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8683..9312
                     /locus_tag="VWX48_001627"
     CDS             8683..9312
                     /locus_tag="VWX48_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU9172216.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9552..10703
                     /locus_tag="VWX48_001628"
     CDS             9552..10703
                     /locus_tag="VWX48_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9172217.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11021..11770
                     /gene="truA"
                     /locus_tag="VWX48_001629"
     CDS             11021..11770
                     /gene="truA"
                     /locus_tag="VWX48_001629"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU9172218.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQVI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11760..12533
                     /locus_tag="VWX48_001630"
     CDS             11760..12533
                     /locus_tag="VWX48_001630"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9172219.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNDLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVSVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            12511..12972
                     /locus_tag="VWX48_001631"
     CDS             12511..12972
                     /locus_tag="VWX48_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9172220.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMIGMIVGFILSQSIKKIK"
     gene            13225..13830
                     /locus_tag="VWX48_001632"
                     /pseudo
     CDS             13225..13830
                     /locus_tag="VWX48_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4028 a         2542 c         3025 g         4235 t
ORIGIN      
        1 gagaatacga ttctccatag tgaccaaggc tggcaatatc aacacgattc ttatcatcag
       61 tttcttgagg gtaagggaat tcaagcatct atgtcacgca agggaaacag ccaagataac
      121 ggtatgatgg aatctttctt tgggattctg aaatcggaaa tgttttacgg ttatgagaag
      181 tcgtttcagt cgcttaagca attggaacaa gccattatag actatattga ttactacaac
      241 aataagagaa ttaaggtaaa actaaaagga cttagccctg tgcaatacag aactaaatcc
      301 ttcggataaa ttaattgtct aacttttggg gggcagtaca tttttggtat atataaaatt
      361 tgtaggagct atatctacaa ttttatattc ccagtttatg gatgtcactt actatattca
      421 caatgttatc cagtgttttt tctctaatat ttaaggagtg ttctgtttct cgaataaatt
      481 cttcaaagtt taacccgtca acttgttcct gaacaagaaa ataatcatcc acgatataaa
      541 attcatcagt taaattagta gtataacttt tatcggctaa tttttttagc atgtgagctt
      601 cattttttat atcatcaaga gctgtccatt ctccttcagc atcataattc acaaaaggtc
      661 ttgactgctt gatgattact ttttgcccgt ccgattttct aattgcccga taaacatttc
      721 ctttatttga tctcttaata attttttcca ttttgtattt atttattgca gagtctttac
      781 ttgaaatttc acatgtggtt tgaaaataat tccttttttc ttcttctgaa aataaatcca
      841 ttttccagtt agggagacta gggaaatttt gtctcttatc ttctacatag ttcttccttt
      901 tttcatctag caataaatag atgacttttt tatttttttc atcataagct tgttttttta
      961 aaaaagcccc atatctataa tgaactggag aatgcattcc acattgatag tcagatagta
     1021 tttttggagc cttaaattct gacagtctat tcgtaagatt acaaatcata ctcttagctt
     1081 cagattctga cttaggatat agagttataa atttgttagc agtagggctc atttccctag
     1141 ggaattaatt ttttttaatt cctctaaatt tttaacgact ttaaagctac aattatttag
     1201 ttgggatagt ttatacacaa tcttaaaaat atttacagcg tcttttattt gggagcttat
     1261 gtgtattttc cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc
     1321 accctgttgg aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa
     1381 ctcctaatta ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac
     1441 ttattttata taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta
     1501 gggagacctg tgacaatgac attttcctct ggaagtagtt ctaattcaaa caatgtttgt
     1561 tccatgactg tatcttcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt
     1621 cgtctgacta aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt
     1681 attttttcta actttctaat tatattctac catgtgtttt ttatatgtca agaattttct
     1741 gaataaactg tttatttttt attttttgat atttttgcaa attgtttaaa atctttcaat
     1801 tggattcact tattacttta ggacattgaa acttctttcg ccagaggtgc ttatattact
     1861 gggaagttga agattgaaat gtggtataat aagaggtaat agagttttgg aaagtgagag
     1921 aagatgattt caaagagatt agaattggta gcttcctttg tgtcacaggg ggctatttta
     1981 ctagatgtgg gaagtgacca tgcttatctg cctatcgagt tggttgagag aggccaagtc
     2041 aaaagcgcta ttgcaggtga ggtggtggaa ggtccctatc agtctgcggt taaaaatgtt
     2101 gaggctcacg gcctaaagga gaaaatccaa gtccgtttag ccaatggctt ggcagctttt
     2161 gaagagactg accaagtgtc tgtcattacc attgctggca tgggtggtcg tttgattgct
     2221 aggattttag aagaaggttt gggtaagtta gctaatgtag agcgtttgat cctccagccc
     2281 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
     2341 gaaagcatct tagaagaagc tggaaagttt tatgagattc tagtagtgga aactggagaa
     2401 atggaattat cagcaagaga tacccggttt ggccccttct tgtcaaggga aatcagccca
     2461 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agtttgccct cggacaaatc
     2521 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
     2581 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
     2641 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
     2701 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
     2761 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
     2821 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
     2881 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
     2941 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
     3001 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
     3061 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
     3121 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
     3181 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
     3241 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
     3301 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
     3361 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
     3421 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag
     3481 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggctgcagca ggaattatca
     3541 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
     3601 atttttatgt ggatttatta gctgatttag agaaatcagg acaaaaaatc gacttttacc
     3661 agcgttcggg agtctttctc ttgaaaaagg atgaatctaa gttggaagaa ctttatcaac
     3721 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
     3781 cctcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
     3841 gtggagcgag agtagatggc cacctcttag tgactcgttt gctggaagcc agtcaggtca
     3901 agctggtcaa agaaaaagtg actctgacac cgttagcatc aggctaccag attggtgaag
     3961 aggagtttga gcaggttatt ttggcgacgg gagcttggtt gggggacatg ttagaaccct
     4021 tgggttatga agtagatgtt cgtcctcaaa aaggacaact acgagattat cagctggtcc
     4081 aagacatgga agcttaccct gttgtcatgc cagaagggga gtgggatttg attccttttg
     4141 caggtgggaa attgtcctta ggcgctaccc acgaaaatga catgggattt gatttgacgg
     4201 tagatgaaac cttgctccaa caaatggagg aggccacctt gactcactat ctgattttgg
     4261 ctgaagctac ttcaaaatct gagcgtgttg gaatccgtgc ctacaccagt gatttctctc
     4321 ctttctttgg gcaggtgcct gacttaactg gtgtctatgc agccagtgga ctaggttcat
     4381 caggcctcac aactggtcct attattggtt accatttagc tcaactgatc caagacaagg
     4441 agttgacctt ggaccctgaa aactacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
     4501 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
     4561 gctgctttga ggttgtggat agaactgacg aagtcagtaa ccatacccat ggcaaggcga
     4621 cgttgacgtg gtttgaattg gattttcgaa gagtataagc attttactga aattttatca
     4681 ggtagtttag gatggcaaat gacattccct gtcaaaaatg gtaaaataag aaaaaataat
     4741 ctgagaatcg aggaaaaaag atgcaagaaa agattttggt aactggtggt gccggtttta
     4801 ttggaaccca cactgttatt gaattgatcc aagcaggcca tcaagttgtt gtggtggata
     4861 atcttgtcaa tagcaatcgt aagagtttag aagttgttga aagaatcaca ggagttgaga
     4921 ttcctttcta tgaggcagat attcgtgaca cagataccct cagagatatt ttcaagcagg
     4981 aagaactgac tggtgtcatt cactttgctg gtttgaaggc tgttggcgaa tcaacacgta
     5041 tccctcttgc ctactatgac aacaatatcg ctggaactgt cagccttttg aaagccatgg
     5101 aagaaaacaa ctgtaaaaac atcatcttca gttcttctgc gacagtttac ggggatccgt
     5161 acacagtgcc catcttggaa gatttcccac tttcagtgac caacccatac ggtcgtacca
     5221 agctcatgct agaggaaatt ttgaccgata tttacaaagc agactcagaa tggaatgttg
     5281 tcttgcttcg ttactttaac ccaatcggag cccatgagag tggtgatttg ggagaaaatc
     5341 caaacggtat tccaaacaat ctcttgccat atgtgactca agtagccgtt ggaaaattag
     5401 agcaagtgca agtgtttgga gacgattacg atacggaaga tggaacaggt gttcgtgact
     5461 atatccacgt tgtcgatttg gctaagggtc acgttgcagc tttgaaaaaa atccaaaaag
     5521 gttcaggact aaacgtttat aaccttggaa ctggtaaagg ttactcagtt cttgaaatta
     5581 tccaaaacat ggaaaaagcg gtgggacgtc ctattcctta ccgcatcgta gaacgtcgcc
     5641 caggtgatat cgctgcctgc tactcagacc cggcaaaagc taaagcagaa ctcggttggg
     5701 aagcagaact cgacatcacc caaatgtgtg aagacgcatg gcgttggcaa agcaagcatc
     5761 caaatggatt tgaagactaa gatgatgatt tcaatcatcg tcccttgttt aaatgaagag
     5821 gaagtacttc ctctttttta tcaggctctg gaagctttac ttccagattt ggaaacagaa
     5881 atcgagtatg tctttgtcga tgatggatca agtgatggga ccttggaact cttaaaggcc
     5941 tatcgggagc aaaatccggc agtccattat atttctttct ctcgaaattt tggcaaagaa
     6001 gcagcccttt atgcaggctt gcaatatgcg acaggagatt tggtggtggt gatggatgca
     6061 gacctccaag atcctcctag tatgttgttt gagatgaaaa atgtactaga caaaaatgta
     6121 gacttggact gcgttgggac acggagaact agtcgggagg gagaaccctt ctttcgcagt
     6181 ttctgtgctg ttctctttta tcgcctcatg caaaaaatca gcccagtagc tctgccgtcg
     6241 ggtgtccgtg actttcgtat gatgagaagg tctgtggtcg atgccatttt aagcttgact
     6301 gagtccaatc gtttttctaa gggactcttt gcctgggtcg gctttaaaac ccactatctg
     6361 gactatccaa atgtcgaaag gcaggctggc aagaccagtt ggagttttag gcaactcttt
     6421 ttttactcca ttgaagggat tgttaatttt tcagatttcc ctttgactat agcctttgta
     6481 gctggtctcc tatcttgttt tctttctctg ctgatgacct tttttgttgt ggttcggacc
     6541 ctcattttgg gcaatccgac atctggttgg acctctctga tggctgttat tctctttctt
     6601 ggaggcattc aactcttgac cattgggatt ctcggcaagt atatcagtaa gatttattta
     6661 gagactaaaa aaagaccact ttatcttatc aaagaaaaaa gtgaccttcc tgattttaca
     6721 gaaaaaataa agtgaaaaga ctataatttt acatggaaat gtgctaaact agagggagtg
     6781 gattatcgcc attgatttag gcttcctggt ttccaatcag ggcgcgagtt gggcaatttt
     6841 taacagcctc taagacatcc tgactaggag aaatttcttt ttccagttgg tcagggtcat
     6901 cgtaaaaacg cacgattcca ttatcatggt aatcaaataa atcagaataa gtttggcaaa
     6961 gcccacaggc gatacatcgt tcaggtataa gtgtgatttt catgttcata tttatattgt
     7021 aataagaaaa gtaaaaaaaa acaaggagta aggtatggca aaagaaccgt ggcaagaaga
     7081 tatctatgat caagaagaat caagagcaga gcgtcggcct cgaaaccacg gaggggctga
     7141 taggatggct aatcgtattt tgacgatcct agctagtatt ttctttgtaa ttgtggtggt
     7201 gatggtcatc gttctcatct atctatcatc gggggggagt aatcgcacag cagccttaaa
     7261 agactttcat gattctgatg caagtgtagt acaaatctca tcttcaagca gttctcagcc
     7321 tgagcagagt tcagagccag aatctacttc tagtagttca gaaggagctg ctaatcctga
     7381 aggaactatt aaagttctcg caggagaagg ggaagcagct attgccgctc gtgcaggaat
     7441 ctccattgct cagttagagg ccttgaatcc tgggcacatg gctacaggat cttggtttgc
     7501 taatccaggt gatgttataa aaataaaata ggagccgata tgaaaacaat tcaaattgct
     7561 attgatggtc ctgcttccag cggtaagagt acggtcgcaa agattattgc taaggatttt
     7621 ggattcacct accttgatac aggagctatg tatcgtgcag cgacctatat ggctcttaag
     7681 aaccaattag gagttgaaga agtcgaagcc cttctagcct tgttggacca gcattcaatc
     7741 agctttggac gttcagaaac tggagaccag cttgtttttg taggagatgt ggatattacc
     7801 catcctatcc gtgaaaatga agtgaccaat catgtttctg ctattgcagc aattcctgaa
     7861 gtgcgtaaga aattggtttc tctccaacaa gaaattgccc agcaaggcgg gattgtcatg
     7921 gatggtcgcg atattggaac tgttgtattg ccacaagcag aattgaaaat tttcctagta
     7981 gcttctgttg atgagagagc agagcgtcgt tacaaggaaa atattgccaa gggaattgaa
     8041 acagaccttg aaaccctaaa aaaggaaatt gctgcgcgtg actacaagga tagtcatcgt
     8101 gagacttctc ctctcaaaca agcagaggat gctgtctacc ttgatacaac tggtttgaac
     8161 attcaagaag tagttgaaaa aatcaaagca gaagctgaaa aaagaatgta aatgtagaaa
     8221 agccgataga ttgatatcgg tttttttcta aatttgtcaa aatgctgatt ttagggtata
     8281 atagttgctg ttcgagaaat tttgattttc aaagaatagt gaatgatgat aaggagaaat
     8341 catgaacaat ttaccaaatt gtccaaaatg taactcagag tatgtctacg aagacggtgc
     8401 cctactggtt tgcccagagt gtgctcatga gtggaatcct gctgaagttg cagaagtaga
     8461 agaaggtctt gtcgctatcg atgccaacgg aaataaattg gctgatggtg atacagtaac
     8521 tctcatcaag gacttgaaag taaaaggtgc gccaaaagat ttgaaacaag ggacgcgcgt
     8581 gaaaaatatc cgcatcgtag aaggcgacca caatatcgac tgtaagattg atggttttgg
     8641 tgccatgaaa ctcaaatcag agtttgtgag gaagatttaa gcatgtcaaa acactataaa
     8701 cttgtatttt atagccgtat cttcttgttt ctagcggctt ttacgggagt ttatcttgaa
     8761 attactaagc atggtggttt tgggatgctt ctctattaca cggttctgtc caacctcttg
     8821 gtaactattt ttacccttta tcttctaaag gttatgagcc gtgtaggtga aaattggcaa
     8881 aggccaagtc tcttgcgctt aaaaggtggg gtcaccatga gtatcatgat tacctgtgtg
     8941 atttaccatt tcctcttggc gcccattgcg actaatttct ataccctaga aaatttcctt
     9001 tgccactata tcgttcccat ctggttttta gcggataccc tcttttttga caaacagggt
     9061 caatacaaga tttgggatcc agcagtgtgg accattttac cctttctgta tatgatgttt
     9121 gctcttttta atggcttggt tctaaaactc aatattccaa atgccaagga taatcctttc
     9181 ccttacttct ttttgaatgt gaacaagggt tggaatgttg tgtttaagtg gtgtctgatt
     9241 atctttgttg cctatatggt agcaggattt attttctact ttatcaagca aatcaagaga
     9301 aagtcatcct aatactcttc gaaaatctct tcaaaccacg tcagtttcca tctgcaacct
     9361 caaaacactg ttttgaacaa cctgcggcta gcttcctagt ttgctctttg attttcattg
     9421 agtataagat acaagggatt cattttcgaa tttaagaagg agtctacaaa ccaatgaggc
     9481 ttcttctttt cttgcttatt tgataactat caaaaaagta gaagattaag agaaatatag
     9541 aaagagattt catgaaacaa tttttagaac gggccagcat tttggctctc tccctcgttt
     9601 tgattacctc cttttccatt tcgagtgccc taccagccat gtttgactat tatcagggtt
     9661 attctaagga acaaattgag ctcttggtga gcttgccttc ctttggaatc atgatgatgt
     9721 tactgctaaa tggtttctta gaaaaaatat ttcctgagcg cttacagatt agtttgggct
     9781 tgctgatttt atcattgagc ggtacagctc ccttctggta ccaagcctat ccctttgtct
     9841 ttggaacacg gcttctcttt ggtttgggtc ttgggatgat caatgccaag gccatttcta
     9901 ttatcagtga acgctaccaa ggaaaaaggc gaattcagat gttagggcta cgcgcttctg
     9961 cagaggtcgt tggagcttct ctcattacct tggccgtcgg tcagttgttg gcctttggtt
    10021 ggacagctat ctttctagcc tatagtgctg gatttttggt gctgcccctt tatctgctct
    10081 ttgtccctta tggaaaatca aagaaagaag tcaagaaaag agcgaaggaa gcaagtcgtt
    10141 taactcgaga aatgaaaggc ttgattttta ccttagctat cgaagcggca gttgtagttt
    10201 gtaccaatac agctattacc atccgtattc caagtttgat ggtggaaaga ggattggggg
    10261 atgcccagtt atctagtttt gttcttagta tcatgcagtt gatcgggatt gtggctgggg
    10321 tgagtttttc tttcttgatt tctatcttta aagagaaact gctcctctgg tctggtatta
    10381 cctttggctt ggggcaaatc gtgattgcct tgtcttcatc cttgtgggtg gtagtagcag
    10441 gaagtgttct ggctggattt gcctatagtg tagtcttgac gacggtcttt caacttgtct
    10501 ctgaacgaat tccagctaaa ctcctcaatc aagcaacttc atttgctgta ttaggctgta
    10561 gtttcggagc ctttacgacc ccattcgttc taggtgcaat tggcttacta actcacaatg
    10621 ggatgttggt ctttagtatc ttaggaggtt ggttgattgt aatctctatc tttgtcatgt
    10681 acctacttca gaagagagct taggattgat tcctaagttt ttcttttgat actcaatgaa
    10741 aatcaaagag caaactatag ttgattgagt ttggaatagt atgctgtagc tgctaaaata
    10801 tttctagaaa ttaatttgac tttcctaata gagttgttca tatcttattt caatctacta
    10861 tagaaagcta gccgcaggtt gctcaaaata gtgtgttgag gttgcagatg gaaactgacg
    10921 tggtttgaag agattttcga agagtatgag atttttatac ccatacagta tttgttttag
    10981 gtccttgttt acagactaat ttcttgataa aatagaggct atgacgagat ataaagcaac
    11041 tatttcctat gatggttatg cctttgctgg ctttcagcgc cagcctcatg cgcgtagcgt
    11101 tcaggaagaa attgaaaaaa ccttgaccag attaaataaa gggcaagtca ttactgttca
    11161 cggtgctggt aggacagata gtggggttca tgccctggga caggtcattc attttgacct
    11221 gccttatcag atggatgagg agaaactccg ttttgccttg gatacccagt ctcctgaaga
    11281 tattgatgtg atttcgattg agcttgtggc agatgatttt cattgccgtt atgccaagca
    11341 tagcaagacc tatgagttta ctgtggatag aggacgtccc aaaaatccga tgcgccgtca
    11401 ctatgctacc cactttccct acccactcga tgtggaacga atgcagattg caatcaaaaa
    11461 gctagaggga acccatgatt ttaccggttt tacagcctct gggactagtg tagaggataa
    11521 ggttcgcacc atcacagaag ctagtttaat agtcgatgag acaggacaat ttttgacctt
    11581 taccttttca ggaaatggtt tcttgtataa acagattcgc aatatggtgg ggactcttct
    11641 caaaatcggt aacaaccgca tgccagtaga gcagattgat ctcatcttgg agaagaagga
    11701 caggcaactt gcaggtccca ctgcagcacc aaatggtttg tatttaaagg agattcgtta
    11761 tgaagaataa tcgtatttta gcactttctg gaaatgatat ttttagtggt ggtggactgt
    11821 cggctgattt ggctacctat accttgaacg acttgcatgg gtttgtagca gtgacttgtt
    11881 tgacagcctt gacagaaaaa ggatttgaag tctttccaac tgatgatacc atttttcaac
    11941 atgaattaga tagcttgcgt gatgtggaat ttgggggaat taagattggt cttctcccta
    12001 ctgtcagtgt ggctgagaag gccttggact ttatcaaaca acgcccagga gtatctgtgg
    12061 tgctggatcc tgtcttggtc tgcaaggaaa cgcatgatgt agctgtcagt gagctctgcc
    12121 aagagttgat tcgctttttc ccttatgtca gtgtgattac gcctaatctc ccagaagcag
    12181 aattattatc cggtcaggaa attaaaacct tggaagacat gaaaactgca gcgcagaaat
    12241 tgcatgattt aggagcgcca gcagtcatta tcaagggagg caatcgtctt agtcaggaca
    12301 aggctgtgga tgtcttttat gatggacaga cctttactat cctagaaaat ccagttatcc
    12361 aaggccaaaa tgctggtgca ggttgtacct ttgcctctag cattgccagt cacttggtta
    12421 aaggtgataa acttttgcca gcagtagaaa gctctaaggc tttcgtttat cgtgctattg
    12481 cacaagcaga tcagtatgga gtaagacaat atgaagcaaa caaaaacaac taaaatcgcc
    12541 cttgtatccc tattaaccgc cctttctgtg gttctaggtt atttcttaaa aatcccaaca
    12601 cctacaggaa ttctaactct tttagatgct ggtgtcttct ttgcggcctt ttactttggt
    12661 agtcgtgaag gagcggtagt cggaggacta gcaagtttct tgcttgacct cttatcaggc
    12721 taccctcagt ggatgttttt tagcttggtc aaccatggct tgcagggatt tttcgcagga
    12781 tttaaaggaa aaagtcagtg gttaggcctt attttagcaa ctattgccat ggtagggggc
    12841 tacgccttgg gttctacttt gatgaatggc tgggcagcag ccctcccaga aattctacca
    12901 aattttatgc aaaatatgat agggatgatt gtaggattta ttcttagtca aagtatcaag
    12961 aagattaagt aatactcttc gaaaatctct tcaaaccacg tcagcttcca tctgcaacct
    13021 caaaacactg ttttgagcag cctgcggcta gctttctagt ttgcactttg attttcattg
    13081 agtataaaaa gatcttggga aaagactcaa tttcagtaga aaaggaagta aatcttccca
    13141 cattaaaacg catattacca aggttcttat gaactgcacc ccaaaagtta gacaaaaaaa
    13201 atctaacttt tgggtgtttt tattatgaaa ttgaattatg atgataaagt tcagatctat
    13261 gaacttagaa aacaaggata tagcttagag aagctttcaa ataaatttgg gataaataat
    13321 tctaatctta ggtatatgat taaattgatt gatcgttacg gaatagagtt cgtcaaaaaa
    13381 ggaaaaaatc gttactattc tcctgattta aaacaagaaa tgagtaataa agtctgacat
    13441 gaaggctgga ctaaagatag agtttctctt gaatacggcc tcccaagtcg tacgatactt
    13501 cttaactggc tagcacaata caggaaaaac gggtatacta ttgttgagaa aacaagagag
    13561 agagtacctg agagcggaga atgccatcct aaaaaagtta agagaactcc gattgaagga
    13621 ggaaaaagag aaagaagaaa gacagaaatt gttcaagaat taatgactga gttttcgtta
    13681 gatcttcttc taaaagccat taaactagct cgttcgacct actactatca cttgaaacag
    13741 ctagacaaac cagataagga ccaagagctt aaagctgaaa ttcaatccat ttttatcgaa
    13801 cacaagggaa attatgctta tcgctgtatt
//
LOCUS       DAVKAU010000047        13659 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVKAU010000047 DAVKAU010000000
VERSION     DAVKAU010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.047"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..178
                     /locus_tag="VWX48_001633"
     CDS             <1..178
                     /locus_tag="VWX48_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9172221.1"
                     /translation="AEDKAYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLR
                     MNLIAGIINHKLEF"
     gene            227..691
                     /locus_tag="VWX48_001634"
     CDS             227..691
                     /locus_tag="VWX48_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU9172222.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            848..1273
                     /gene="lacA"
                     /locus_tag="VWX48_001635"
     CDS             848..1273
                     /gene="lacA"
                     /locus_tag="VWX48_001635"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU9172223.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSHMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1304..1819
                     /gene="lacB"
                     /locus_tag="VWX48_001636"
     CDS             1304..1819
                     /gene="lacB"
                     /locus_tag="VWX48_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU9172224.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHVETHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1830..2759
                     /locus_tag="VWX48_001637"
     CDS             1830..2759
                     /locus_tag="VWX48_001637"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU9172225.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            2761..3741
                     /gene="lacD"
                     /locus_tag="VWX48_001638"
     CDS             2761..3741
                     /gene="lacD"
                     /locus_tag="VWX48_001638"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU9172226.1"
                     /translation="MALTEQKRARLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3975..4811
                     /locus_tag="VWX48_001639"
     CDS             3975..4811
                     /locus_tag="VWX48_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9172227.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4847..5164
                     /locus_tag="VWX48_001640"
     CDS             4847..5164
                     /locus_tag="VWX48_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9172228.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5164..6855
                     /locus_tag="VWX48_001641"
     CDS             5164..6855
                     /locus_tag="VWX48_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9172229.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7070..8476
                     /gene="lacG"
                     /locus_tag="VWX48_001642"
     CDS             7070..8476
                     /gene="lacG"
                     /locus_tag="VWX48_001642"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9172230.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVNNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8519..8776
                     /locus_tag="VWX48_001643"
     CDS             8519..8776
                     /locus_tag="VWX48_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU9172231.1"
                     /translation="MFKDFIQSIYEKVYIINFEKYSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDDLEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(9055..9816)
                     /locus_tag="VWX48_001644"
     CDS             complement(9055..9816)
                     /locus_tag="VWX48_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9172232.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9998..10960)
                     /gene="nrdF"
                     /locus_tag="VWX48_001645"
     CDS             complement(9998..10960)
                     /gene="nrdF"
                     /locus_tag="VWX48_001645"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU9172233.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11148..13307)
                     /gene="nrdE"
                     /locus_tag="VWX48_001646"
     CDS             complement(11148..13307)
                     /gene="nrdE"
                     /locus_tag="VWX48_001646"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU9172234.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13388..13606)
                     /gene="nrdH"
                     /locus_tag="VWX48_001647"
     CDS             complement(13388..13606)
                     /gene="nrdH"
                     /locus_tag="VWX48_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU9172235.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
BASE COUNT         4218 a         2456 c         2794 g         4191 t
ORIGIN      
        1 agctgaagat aaagcctata accatgcgct atctaaggag agaagcaaag ttgagaacat
       61 ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg
      121 cttcggatta cgaatgaatt tgattgctgg tattatcaat cataaactag aattctagtt
      181 ttgcaggaag tctaataaag aaactagcaa ggtcaggcct tactttattg gtggacatcc
      241 aggatttaat tgtcttctac ttgatgatga agtctatgaa gattattatc tagagtttga
      301 gaaagaagag atttgctctg ttccacgtcc tttcccagaa acaggtatgt tggatttcca
      361 agatagaagt ccatggctag agggacaaaa agaaatagat cttagttatg atcttttcag
      421 cacagatgca gtgactttgg atgaattgca atctcgaaca attgcccttc gttctcttaa
      481 acatgataag ggattgaaag tgcattttgc agaatttcca aacctcatca tctggtcaac
      541 tttgaacaag ggacctttca ttacctttga accatggtct ggcttgtcaa cattccttga
      601 agaaggagat catttagaag ataagaagaa tgtttgtctc ttagaagcca atcaggttga
      661 agaattaggg tttgagatag aagttttata aaaaagtaaa aaataaataa caaaaacaaa
      721 cacaaactgt tgacttcttc aaacaatagt agtatattat gtttgtgagg actaattgac
      781 tgttttttaa agacagccaa tacactgctg gaatccagca tagaaaaaat aaaaaggagt
      841 atacaatatg tctattgtta tcggtgcaga tgctgcaggt ttgagattga aagaagttgt
      901 gaaagacttc ttagaaaaag aaaacttcca ccttgtggat gttacagctg aaggtcaaga
      961 ctttgttgat gtgactctcg ctgttgctgc agaagtaaac aaagaagaac aaaaccttgg
     1021 tatcgtgatt gatgcttatg gagctggtcc atttatggtt gcaactaaga tcaaaggaat
     1081 ggttgctgca gaagtatctg acgaacgttc agcttatatg actcgtggcc acaacaactc
     1141 acatatgatc actatggggg cacaacttgt tggtgatgaa ttggctaaaa acatcgctaa
     1201 aggatttgtt aatggtaaat acgacggtgg acgtcatcaa atccgggttg acatgttgaa
     1261 caaaatgggc taattagatt acagtaagaa aggtaagtta aaaatgagaa ttgcaattgg
     1321 atgcgaccac atcgtaacag atgaaaaaat ggcggtttca gaatttttga aatcaaaagg
     1381 atatgaagtc attgactttg gtacatatga ccatacacgg actcactacc caatctttgg
     1441 taaaaaagta ggggaagctg taactagcgg ccaagctgat cttggagtat gtatctgtgg
     1501 tactggtgtt ggtatcaaca acgctgtaaa taaagttcca ggtgttcgct ctgccttggt
     1561 tcgtgatatg acaacagccc tttatgctaa agaacaattg aacgccaacg ttatcggttt
     1621 tggtggtaag attactggtg aattgctcat gtgcgatatc atcgaagctt tcatccatgc
     1681 tgaatacaaa ccatctgaag aaaacaaaaa attgattgcg aaaattgaac atgttgaaac
     1741 acacaatgct caacaaacag atgcaaactt cttcactgaa ttccttgaaa aatgggatcg
     1801 cggagaatac cacgactaag aggtgaccta tgattttaac agtcacaatg aacccatcca
     1861 ttgatatttc ctatcccttg gatgagttga agattgatac tgtcaatcgt gtggtagatg
     1921 taaccaaaac ggctggtggt aaagggctca atgttacacg cgtactttca gaatttggcg
     1981 attctgttct tgctactggt ttagtaggtg gcaaacttgg tgagtttttg gttgaacata
     2041 tcgataatca agtaaagaaa gatttcttct caattcaggg agaaactcgt aactgtatcg
     2101 ctattctcca cggagacaac caaacagaag ttcttgaaaa aggtcctgaa gtattggaac
     2161 aggaaggtca agactttttg gaacatttca aaaaactctt ggagtcagtt gaagtagtgg
     2221 ccatctcagg tagtctgcca gctggccttc cagttgatta ctatgcgagc ttggtagaac
     2281 ttgctaatca agctggcaag cctgtagtct tggactgctc aggtgcagca cttcaggctg
     2341 ttcttgaatc accccataaa ccaacagtca tcaaaccaaa taatgaagaa ttgtctcagc
     2401 ttcttggaag agaagtttct gaggatttgg atgaattaaa agaagtactt caagaacctt
     2461 tgtttgcagg gattgaatgg attatcgttt cacttggtgc taacggtact tttgccaaac
     2521 atggtgacac tttctacaag gtagatattc ctagaattca ggtggtaaat cctgttggat
     2581 ctggagactc tactgtggca ggaatttctt caggacttct tcacaaagaa tcggatgcag
     2641 aattactcat caaggcaaat gtccttggta tgctcaatgc tcaagaaaaa atgactggtc
     2701 atgtcaacat ggccaactat caagttctat atgatcaatt aatagtaaaa gaggtataaa
     2761 atggctttaa cagaacaaaa acgtgcacgc ttagaaaaac tttctgatga aaatggtatc
     2821 atctcagctc ttgcatttga ccaacgtggt gctttgaaac gcctcatggc tcaacaccaa
     2881 acagaagaac caactgtggc tcaaatggaa gaactgaaag tcttggtagc agatgaattg
     2941 actaaatacg cttcatcaat gcttcttgac cctgagtatg gacttccagc aactaaagct
     3001 cttgatgaaa aagctggtct tctccttgct tatgaaaaaa caggttatga cacaacaagt
     3061 acaaaacgct tgccagactg cttggatgtt tggtctgcaa aacgtattaa agaagagggt
     3121 gcagatgcag ttaaattctt gctttactat gatgtagata gttcagacga actcaaccaa
     3181 gaaaaacaag cttatatcga gcgtatcggt tctgagtgtg tggctgaaga tatcccattc
     3241 ttccttgaaa tccttgctta cgatgaaaaa attgcagacg caggttctgt agaatatgcg
     3301 aaagtaaaac cacacaaagt tatcggtgct atgaaagtct tttcagaccc acgctttaac
     3361 attgatgtct tgaaagttga agttcctgtt aacattaaat atgttgaagg cttcgctgaa
     3421 ggtgaagtgg tttacacacg tgaagaagca gcagccttct tcaaagcgca agatgaagca
     3481 acgaacttgc catacattta cttgagtgct ggtgtatcag ctaaactctt ccaagatact
     3541 cttgtatttg ctcatgaatc aggtgcaaac tttaacggag ttctttgtgg ccgtgctaca
     3601 tgggcaggat cagttgaagc ttacatcaaa gatggtgaag cagcagctcg cgaatggctt
     3661 cgcacaactg gatttgaaaa cattgatgag ctcaataaag ttcttcaaac aacagcgact
     3721 tcatggaaag aacgtgtgta agaaagtcct cctagtttag gaacatgaat ctaaaaaaat
     3781 ttaaaaaaag ttgtatgtaa aggtttacaa aataacttac ttgtgctata cttaaatcac
     3841 aagttaatac aaggtgagtg ttactaagta atattaggca tgatcacagg tgaattagaa
     3901 atcagctgat tttctagttc atttgtggtc attttttgta ctcatatact tttaagatat
     3961 aaaaggaggt tgacatgtat cgaattctaa atccaatgaa tcacaatgtc tcgcttgtca
     4021 gaaatgataa gggagaagag gtgattgtaa ttggtaaggg gattgcattc ggaaagaaga
     4081 agggggattt gattgctgaa aatcaggttg agaaaatctt tcggatgaag accgaagagt
     4141 ccagagaaaa ctttatggct cttctcaaag atgttccgct tgattttatc acagtgacct
     4201 atgaaatcat tgataagcta tcaaagaaat atcattatcc gattcaagag tatctctatg
     4261 taaccttgac agatcatatt tactgttctt atcaagctct aactcaagga aggtacaagg
     4321 atagtaatct gccagatatt tccgctaagt atcctgtcgc ttttcaaatc gcaaatgaag
     4381 cttttgaaat ttaccgtcag aagctagcag atcattttcc tgaggacgaa attattcgga
     4441 ttgcttatca tttcattaat gctgaaggtg aaaatgaagt ggaacttgtg gagtcgattg
     4501 ataagaggaa agaaattctc aggaatgttg aagaagtttt aacggactat gcaattcaac
     4561 gaactaaaaa gaataaccat ttctatgatc gctttatgat ccatttgaat tatttcttgg
     4621 attatttaga cagatctaga gatgataacc aatcacttct ggatatggaa gatcatatta
     4681 aacaatccta tccaaaagcc ttcgagattg gttccaagat ctatgatgtg attacgcaac
     4741 atacgggtct tgatttgtat aaaagtgaac gagtttatct agttctacat atccaacgtt
     4801 tattgtcata aaaatttatt taaaactata taaggagaat tctatcatga atagagaaga
     4861 agtaacattg ttaggttttg aaatcgtagc ctatgctggc gatgctcgtt caaaactatt
     4921 ggaagccttg aaggctgctg aagctggtga ttttgaaaaa gcggacgctc tggtagagga
     4981 agctggtagc tgtattgcag aggctcacca cgcgcaaaca agtctattga ctaaggaagc
     5041 ttcaggtgag gacttggctt atagtgtaac catgatgcat ggccaagacc acttaatgac
     5101 aactatcttg ttaaaagatt tgatgcatca tttaattgaa ctctacaaga gaggagttaa
     5161 ataatgaata aactaattgc atttatcgag aaaggaaagc ctttctttga aaaactatct
     5221 cgtaatatct atcttcgtgc tattcgtgat ggtttcattg caggtatgcc tgttattctc
     5281 ttctcaagta tctttatctt gattgccttt gtaccaaact catggggctt taaatggtct
     5341 gatgaagttg tagcctttct gatgaaacct tatagctatt ctatgggtat tctggctctc
     5401 ttggtagctg gtacaacagc taagtcattg actgactcag taaaccggag catggaaaaa
     5461 accaatcaaa tcaactatat gtcaacattg ttggcagcaa ttgttggttt gttgatgttg
     5521 gcagctgatc ctatcgaaag tggtctagct actggattct tggggacaaa aggtttgctt
     5581 tcagccttcc ttgctgcctt cgttactgta gccatctata aggtttgtgt taagaacaac
     5641 gtcactattc gtatgcctga cgaagttcca ccaaatatct cacaagtctt taaagatgtg
     5701 attccattca ctctctcagt tgtttcactt tatgctcttg atttactagc tcgtcatttt
     5761 gttggtgcaa gcgtagctga atcaatcggt aaattctttg caccactctt ctcagcagca
     5821 gacggatacc ttggtattac cattatcttt ggtgcctttg ccttcttctg gtttgtgggt
     5881 attcatggtc catctattgt tgaacctgct atcgcagcaa ttacctatgc aaatgctgaa
     5941 gtcaacttga accttctcca acaaggtatg cacgctgaca agattcttac ttctggtaca
     6001 caaatgttta tcgttaccat gggtggtact ggtgcgacac tggttgttcc attcatgttc
     6061 atgtggttaa caaaatcaaa acgtaaccgt gcaatcggac gtgcttcagt agttcctacc
     6121 ttcttcggtg taaatgagcc aatcttgttt ggtgcacctc ttgttttgaa tccaatcttc
     6181 ttcattccat ttatctttgc tccaattgca aacgtatgga tctttaaatt ctttattgaa
     6241 actcttggaa tgaactcatt cactgctaat ctaccatgga caaccccagc tccactaggt
     6301 ctagttcttg gtactaactt ccaagttcta tcattcattc ttgctgccct tctaatcgtg
     6361 gttgacgttg tcatttacta tccattcctt aaggtctatg atgaacaaat tcttgaagaa
     6421 gaacgttcag gtaagtctaa tgatgaattg aaagaaaaag ttgctgcaaa cttcaacact
     6481 gcaaaagcgg atgctattct tgaaaaagca ggtgtagaag cagcacaaaa tacaatcact
     6541 aaagaaacaa atgtcctcgt tctttgtgca ggtggaggaa caagtggtct ccttgcaaat
     6601 gctctaaaca aggcagcagc agaatacaat gtccctgtga aagcagcagc aggtggctat
     6661 ggtgctcacc gtgaaatgtt gccagagttt gatttggtta tccttgctcc tcaagttgct
     6721 tcaaactttg aagatatgaa ggcagaaaca gataagctcg gtattaaact tgctaagaca
     6781 gaaggcgctc aatacatcaa attaactcgt gatggaaaag gtgccctagc attcgtacaa
     6841 gagcaattcg attaaggcta ggaactgtga aacagtctcc catcgttacg gaaatcgcta
     6901 tggcgaattt cctaatcgcc ttattaattc gtcggtaaaa agatatcgtt tttacctcct
     6961 catgtcacaa ttcggtgact tggtacaaga agtgagatgg agaaggatgg ctcactgact
     7021 cctctcctct cacttttact ttatttaaat caagaaatag gtgaaaaaaa tgacaaaaac
     7081 acttccaaaa gactttattt ttggtggcgc aacagctgcc tatcaagcag aaggtgctac
     7141 acatactgat ggtaaaggac cagtagcgtg ggataaatat cttgaagata actactggta
     7201 cactgcagaa ccagccagtg atttttacaa tcgatatcca gttgacctca agctagcaga
     7261 agagtatggt gtcaatggca ttcgaatttc tattgcctgg tcacgtattt tcccgactgg
     7321 ttatggtcaa gtaaatgcta aaggtgttga gttttatcat aatttatttg cagagtgtca
     7381 caaacgtcat gttgagccct ttgtaactct tcatcacttt gacacgccag aagctctcca
     7441 ctcaaatgga gacttcttaa accgtgaaaa tatcgaacat tttgtagact acgctgcctt
     7501 ctgttttgaa gaatttccag aagtaaacta ttggacaacc tttaatgaaa ttggaccaat
     7561 cggtgatggt caatatttgg ttgggaaatt ccctccaggt atccagtacg accttgccaa
     7621 agtctttcaa tcacaccaca atatgatggt gtctcatgca tgcgcggtaa aattgtacaa
     7681 agagaaaggc tataaagggg aaattggtgt tgttcacgcc ctgcctacta aatatcctct
     7741 agatcctgaa aatccagcag atgttcgtgc agcagagttg gaagatatca tccacaataa
     7801 attcatctta gacgcaactt atctaggtcg ctattcagct gaaaccatgg aaggtgtcaa
     7861 ccatatctta tcagtcaatg gtggtagttt ggatcttcgt gaagaagatt ttacagcatt
     7921 agaagctgca aaagacttga atgatttcct aggaatcaac tactatatga gtgactggat
     7981 ggaagccttt gatggagaaa ctgaaattat ccataatggt aaaggtgaaa aaggaagctc
     8041 taagtatcaa atcaaaggta ttggtcgtcg tgtagctcct gactatgtat cacgcacgga
     8101 ttgggattgg attatctacc ctcaaggttt gtatgaccaa atcatgcgtg tgaagaaaga
     8161 ttatcctaac tacaagaaaa tttatatcac tgaaaatggt ctcggctata aagatgagtt
     8221 cgttaataac actgtttacg atgatggtcg tattgattac gtgaaacaac acttggagat
     8281 cttgtctgat gcgattgcag atggagctaa tgtaaaaggt tacttcattt ggtcattaat
     8341 ggatgtcttc tcatggtcaa acggttatga gaaacgttat ggtctcttct acgtagattt
     8401 tgaaactcaa gaacgttatc ctaagaaatc agctcactgg tacaagaaag tagcggaaac
     8461 tcagattata gactagtaga attagtcatt agatatagaa ttttagtgag tcaaaaagat
     8521 gttcaaagat tttatccaat ctatttatga aaaagtttat attataaatt tcgaaaaata
     8581 ctctcaaata ccgtgtttga cgagtgaaga attgaaaagt cttggaaaat ggtatgtctc
     8641 gactggtaaa gaatggattt gtcattcaga tgatgatctg gaagaattta aaaatctatt
     8701 tttaaatttt atcaatcctg aagaatggga tactatctcc tttgattcag attttatgcc
     8761 gtttcaacaa tcgtaaccaa tttctcaaaa aagttaaatc ttatatttag tactctgtaa
     8821 aactcttatc taatcacgtt gcttatactc aatgaaaatc aaagagcaac tttaaactag
     8881 gaagcgagtc gcagatttct caatgtatag ctttgaggaa ttgggcaaaa agtctttgat
     8941 atagaaaaaa gcatagtatc aggtgtttca acacctgata ctatgctttt tattgtggga
     9001 agatttactt tttttcttct gaaattgagt tgttacccag gctctttcag tttattaagg
     9061 cttgatgact ttaatgtgtt tagatagctt aaaaaggatt gaatcactta gtttagaatc
     9121 tgaaacaata gtatcaagat ttgatatatt ataaaaagta taaaaatcaa acttattgaa
     9181 cttactatga tctgcgagta aatatttttt attagaatta tttaaagcga tgcgttgagc
     9241 ctctccctct tcctcgctaa aagtagctag agctccgttt tgaataccat tacagctaac
     9301 gaaagcttta gaaaattgga gattagagag attttgtagg gtcaatgtgc caacaaaagc
     9361 acctgtaata tcgcgataat ttccacctat caaaatcaaa tctgttaatt ttcgttcgct
     9421 taaaatcaga aaaacaggta gactgttggt tacgacgcgg atattgtcaa taggcaactc
     9481 acgcgcaaaa aactctaatg ttgttcctgg tccaatgaaa atagtttctc tttcttctac
     9541 tagactgcct gcaaaatggg ctatttcttg tttttctgcc gtttggaggg cttgtttttc
     9601 aatatttgat cgctcattag tcaaaaggga gttggttcga agtttttcag ctccaccatg
     9661 cacacgaatc agcaaatctt tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc
     9721 tgaaacggct atttcgtcca taatctgttt aactgttatg gttcctttac tatttactat
     9781 ctctaaaatt ttggttaatt tttcttgttt gagcatatta tcacctcgtt tcctactact
     9841 atcttaccat aaacaaactc atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa
     9901 aaatatcgaa gtttgttttc aaaactttcg atatttttgt tgggttataa ctttgatgtt
     9961 tctagtttac tttttgatga ttgagagtga tggagaatta gtctaaaccg tagttatagt
    10021 catcgtcttg catggcttca acttcgccaa gaaggtaacc atttccgact tgagagaaga
    10081 agtcatggtt ggaagttcct gttgaaatac cgttcataac gattgggttg acatcttcag
    10141 ctgaatctgg gaaaagtgga tcttgtccca tgttcatgag agctttattg gcattgtagc
    10201 gaaggaaggt tttaacctct tcagtccaac caacaccgtc ataaagactc tctgtgtagc
    10261 cttcttcatt ttcataaaga gtatagagta ggtcgtacat ccattctttg agtttttctt
    10321 gctcttcttc aggcaattca ttgaaaccaa gttggaattt gtaaccaatg taggttccgt
    10381 gaacagactc gtcacgaata atcaatttaa tgatttctgc aacgttggct agtttgttgt
    10441 taccgagata gtagagggga gtgaagaaac cagagtagaa gaggaaggtt tcgaggaaga
    10501 cgctggcaac tttcttttca agtgggctgc cgtttaggta gatttcgttg acaatctcag
    10561 ccttcttttg taggtaagga ttggtattgg tccattcgaa aatttcttca atctcagcct
    10621 tagtattcaa ggtagaaaag attgatgagt aagatttagc gtggacagat tccataaatt
    10681 ggatgttatt gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga agggcttgaa
    10741 ccccagtttc agattgcata gtgtcaagaa gggttaaacc accaaaaact tttccgacca
    10801 agtctttctc tttgttagat agctttctcc agtcatccaa gtcgtttgat aagggaatac
    10861 gtgtatcgag ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg atgacatctt
    10921 cgatggcatt ccagttaatg gctttgtagt aagtttccat ttaaaatctc tttctgtgtt
    10981 tagtattgcg aactcacaat tatttctact ttaccataat tctataggag tatcgcacaa
    11041 aaagtcggaa gcccgacttt taaaatgtta cataaattat gttatgacat agtagatttg
    11101 attttatctg tgctgcttag ggaaaaataa tgtttctatg ctagaaacta aatcacacag
    11161 ctttcacatt ggttggcgcc gacttctcca ccgtcatctg taaaggtacg gacgtagtag
    11221 atagacttga ttcccttgtt aaaggcatag ttacgaagga tggacaagtc acgtgtcgtt
    11281 tgtttatttt ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg catgaagagg
    11341 gtgagtgaaa gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc gatgacttta
    11401 cgcatatcca tatcgtaggc agaagtgtag taaggaatgg tttctgtaga caagccagca
    11461 gcagggtagt agattttacc aattttcttc tcttggcgtt cttcgatacg ttgcgtaatc
    11521 gggtggatag aagcagaaac gtcgttgata tagctgatag aaccatttgg cgctacagca
    11581 aggcgatttt ggtggtaaag accatcttct tgaaccttgt cgcgaagttc agcccaatca
    11641 gcaacaccag ggataaagac atttttgaag agttctttaa cacggtctga tgttggaaca
    11701 aattcaccag ttacatactt gtcaaagtaa cttccgttag catagtctga tttttcaaag
    11761 ttgtggaagg taataccacg ttcacgcgca atattgtttg actctaccaa ggtccagtag
    11821 ttcataagca taaagtagat gcttgtaaat tcaacagact caggtgaacc atattcaatg
    11881 agttgttggg caaggtagct gtgcagtccc atggcaccga gaccaaaggt gtgggcttgg
    11941 ctatttccat ggtcaatcgt tggtacagct acgatatgtg aactatctgt aacgaaagta
    12001 agggcacgaa ccatagcacg gatagaacga ccaaaatcag gtgaagtcat catgttaacc
    12061 acgttggttg aacccaggtt acatgaaaca tctgttccca tttgaaggaa ttcttgagca
    12121 tcgttgatca agcttggttc ttgaacttga agaatctcag aacacaagtt actcatgata
    12181 atctttccat caacaggatt tgcacggtta gccgtatcta tgttgactac ataaggatag
    12241 ccagactctt gttgcaattt agagatttca gtttccaaat cccgcgcctt gatttttgtc
    12301 ttgcgaatat ttggatttgc gaccaattca tcgtattttt cagtaatgtc gatgtaattg
    12361 aatggcacac cgtattcttt ttctacagag taagggctga agaggtacat ttcttcattt
    12421 ttacgagcca attcgtagaa tttatcaggt actacaacac caagtgatag agtcttgaca
    12481 cgtacttttt catcagcgtt ttctttctta gttgaaagga aagcgatgat atctgggtga
    12541 aagacgttga ggtagacaac accggcacct tgacgttgcc ccaattggtt ggagtaagag
    12601 aagctgtctt caaaaagctt cataacagga acgacacctg aagcagctcc ttcatagcct
    12661 ttgataggtg caccagcttc acgaaggttg ctgagggtaa ttcccacacc accaccaata
    12721 cgtgaaagtt gaagagctga gttgatagaa cgtccgatag agttcatatc atccgtcact
    12781 tggattagga aacaagatac caactcccca cgacgagcac gtccagcatt caagaaggaa
    12841 ggagtagcag gttggtagcg ttggtggatg atttcattgg caatatcgat tgcaacagct
    12901 tcattcccat cagcgaaata aagggcgttg aagaagacac ggtcttccat attttcaaga
    12961 tagtattcac cgtcattagt ctttaaggca tattgattgt aaaatttata agctgccatg
    13021 aatgacttga attggaagtt ttggtctttg ataaattgag ccaattcttc caagaactct
    13081 ggacggtatt tcttgataaa ggctgtttcg atgtagttgt gttcaatgag gtaattgatt
    13141 ttgtctttga ttgaatcaaa aaccatagtg tttggaacta cattttcttt aaagaaagca
    13201 tccaaggctt ccttatcttt atgaagcatg atttgtccat taacaggacg gttaatttcg
    13261 ttattaagac ggaagtaagt cacgtcttca agatgtttta atcccataaa atttccctta
    13321 tctaattaca aaagaaaggc ttctaagtta gccctaaaag cagtttcttc tggatgatgt
    13381 actaagatta tgctaattgt ttcagttttc ctggttggaa acctgaaaag acttcagttg
    13441 gtgtttggat aacaggagct gcgctaaaac cgagctcttt aacttgatcg acgtactcag
    13501 gttgctcatc aagattgatt tcacgataag agacattatt actgtccaag aaacgcttgg
    13561 tcattttaca ttggacacaa ttgtttttag aataaacggt taccattgtg taactcctct
    13621 tcaaaattta atactatctt agtatatcag aaaataaaa
//
LOCUS       DAVKAU010000048        13629 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVKAU010000048 DAVKAU010000000
VERSION     DAVKAU010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13629
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.048"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            117..1124
                     /locus_tag="VWX48_001648"
     CDS             117..1124
                     /locus_tag="VWX48_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9172236.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTMKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            1127..1327
                     /locus_tag="VWX48_001649"
     CDS             1127..1327
                     /locus_tag="VWX48_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9172237.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            1479..1661
                     /gene="rpmF"
                     /locus_tag="VWX48_001650"
     CDS             1479..1661
                     /gene="rpmF"
                     /locus_tag="VWX48_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU9172238.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            1677..1826
                     /gene="rpmG"
                     /locus_tag="VWX48_001651"
     CDS             1677..1826
                     /gene="rpmG"
                     /locus_tag="VWX48_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9172239.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2248..4128)
                     /locus_tag="VWX48_001652"
     CDS             complement(2248..4128)
                     /locus_tag="VWX48_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9172240.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLATVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERMLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(4122..4991)
                     /locus_tag="VWX48_001653"
     CDS             complement(4122..4991)
                     /locus_tag="VWX48_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9172241.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGVSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAATGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVDNFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(5075..7720)
                     /locus_tag="VWX48_001654"
     CDS             complement(5075..7720)
                     /locus_tag="VWX48_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU9172242.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(7811..9091)
                     /locus_tag="VWX48_001655"
     CDS             complement(7811..9091)
                     /locus_tag="VWX48_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU9172243.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDSLLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCDVNDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            9262..11346
                     /locus_tag="VWX48_001656"
     CDS             9262..11346
                     /locus_tag="VWX48_001656"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU9172244.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGEDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGTSIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFEITGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(11386..13065)
                     /locus_tag="VWX48_001657"
     CDS             complement(11386..13065)
                     /locus_tag="VWX48_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU9172245.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPTLSADFAYRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
BASE COUNT         3788 a         3211 c         2765 g         3865 t
ORIGIN      
        1 caccttttaa aagaaattat tgggctgaaa gtttttagtg attattttca actttctatt
       61 gacttttaaa aacaaagtga tatcatttag atatcaaata atgggaggtc attcttatga
      121 ctgaaaaact aatcaattca aaaccaaatg gtgtattcgc attgattctc attgagttga
      181 caatcgtact tggtatcttt atatttataa tgggtgttgg ttcggaaaac atttttggaa
      241 ttattatcgg acctttacta atcgtaattg caggtctagc tcatgctggt ttaaaagttg
      301 tcaaacctca ggaagctctg gttctgacac tctttggtaa ttatacaggt accatgaaag
      361 aacctggttt ttactttgtc aatcccttca gcgtagcagt caaccctgca aaccacactc
      421 gacttggaca aagtggtgat gttagcacaa aatctccttt tttaggagct aaatcatcaa
      481 atgacaatga tgtaaatctt gaaattggca agaaacacat ttccctcaaa gtcatgacct
      541 tgagcaattc tcgtcaaaaa atcaatgatt gcttaggaaa ccctgtagaa atcggtatcg
      601 cggtaacttg gagagttgtc gataccgcta aggcagtctt caacgttgat aactacaaag
      661 aatatctttc attgcaatgt gatagcgccc tccgtaatat tgtccgcatc tatccttacg
      721 atgtgtctcc taatgtggat actacgggtg acgggcaagc agatgaaggt agtctccgtg
      781 gctctagcga aattgttgct aaccgtattc gtgaggaaat tcaaagtcgc gtagaagatg
      841 ctggcttgga aatccttgaa gcacgtatca cttacctagc ttatgctcca gaaattgctg
      901 ccgttatgct tcaacgccaa caagcatctg ccattattga tgcacggaag atgattgtag
      961 atggtgctgt aggaatggtt gaaatggcac tagaacggct caatgaaggg gaattggtag
     1021 aacttgacga agaacgaaaa gctgccatgg tttcaaatct ccttgtcgtt ctttgtggca
     1081 atcatgatgc acaaccaatt gtcaacacag gaagtcttta ctaaagatgg ctgaagctaa
     1141 aaaaaagcag atcccccttc gactctcaac aaagttatac gctgcactcg catcatgggc
     1201 agaagacgac tttcgttcag tcaatgggca aatcgaatat ctcctcacag agtgtgtcaa
     1261 gcaacggaaa aaagacggaa aatacgtatc agaaaccatt gacgaaccat ttgagattga
     1321 tatttaacac cttctcctgt ctgccgtgtc ggataggaga attttttcat ctttttttgt
     1381 caagtaactt tactttacaa aaaaaatgtg ttatcctagt atggttgatg aaaatcagta
     1441 gattgaatcg aatataaata cctaaaggag aaatcaaaat ggcagtacct gcacgtcgca
     1501 cttcaaaagc gaagaaaaac aaacgtcgta cacactacaa agtaacagct ccatctgtaa
     1561 actttgacga aactactgga gattactcac gttctcaccg tgtatcactt aaaggatact
     1621 acaaaggacg taaaatcgct aaagctgcat cagctgaata atagaaggga gataccatgc
     1681 gcgtaaatat tacacttgaa cacaaagaat ctggtgaacg cttgtacctt acttctaaaa
     1741 acaaacgtaa cactccagac cgccttcaat tgaagaaata ctcaccaaaa cttcgcaaac
     1801 acgttgtgtt tacagaagtt aagtaagcat tcaatacgaa tcaatacaga agaaaaacgc
     1861 ttgatcagcg ttttttcttt ttgttaattt cactatattg caagggaaat cattcgaatg
     1921 actacattat tgataatatt tgttaagcca tcaaaagtaa ttaacatttc atagcgagta
     1981 atcctattta aactcgtccc actatctatt tcttcttatc tctgtgttat aatcccgact
     2041 ttatcataag tttgtctaac tgtagcattt gaaaccagat aattcttctg tttcacgcga
     2101 aacaccctgc gccaagcaag gtgttcttgt tttcatactc aatgaaaatc aaagagcaaa
     2161 ctaggaagct agctgcaggc tgctcaaaac actgttttga ggttgtagat ggaagctgac
     2221 gtggtttgaa gagattttcg aagagtatta agtcgtataa atcgtcgaag ctgtcgcaat
     2281 ggtatgccac tggttagctg tagttgctgc gaaatccttg tctgcgtaga agtcagtaaa
     2341 tggtaggatt tcaacttcca gctcgtcgat acggtcaagc tggccagcca gataaacctc
     2401 gatacggctt tctgctcgtt tgatgcgttg caagagtccg cccatacgga tgtcaactgt
     2461 atccaaacca aagaccttgt tttctttcag ccattggtga ctaaagaggg catggaagtc
     2521 ttcaatttgg cttctaagtt ctggtaattc ttgtctggcg atttgttgta aactttcttt
     2581 atcatccgct tggtaggcat gacgaatgcg tcgtcccaca tctactttgc tacttaaaat
     2641 agcattcaac tgggcctgag tttcaaagag ataagcatag tttccagctt tttctttaat
     2701 gtcagcaata gttcccgccg cctgagcgaa gtgtggcttg tcctgttcag gtgtcatgtg
     2761 tcggtcaagt atcggacaga gaacatcctg ataaaagaca tagcggttgg gattgatgcc
     2821 actgagatta cctggtaggt ctggtaagag gttggcaaga tcaatctgca taaaatcctc
     2881 aaccgttaga ccagtattgg tcttgaaatg cgcagacaaa ctatctaggt cattgcgata
     2941 gctgagttct gcccagattt gcaagcttgg taggatagag aactgggcag tttcaccacc
     3001 attgtctccc caacccgtta cgatgacttc tttaatctga ttggcacggc aggctttatt
     3061 agcctcgata gccactagac ggctaaaatg gttgtgaggt gtaaagccaa tccacttcca
     3121 agctccccct gcaaatgcaa ggtcatggct aatcttgtga tgattgcgga aattacggtt
     3181 gtatttttcc tcgctatcct gataataatc ccagtaaacc agagtcacac ggtctttgag
     3241 acggtctagg tagacacgag tttcctctgg aatttccaca tcacggtcgt actggccatc
     3301 cgctgacatg agtttgaaga acatatcact ccacatctgg cagtggaaac catatttgtc
     3361 agcaatatcc agcatgcgct ccaagtgttg gcacatgagg agactacgat ccacaacacc
     3421 gttcaaaatc aggtagcgtc ccaaaccaac caagtgggct tcgtccatcc cgatattgac
     3481 cttgcgagtc ttcagtttag acaacgtggc aaacatgcca tcaatcaggt cataaacctt
     3541 ttcttcgcca atgagaagaa tgtcctctac atcacggagc tcctgcactt ccttgacacc
     3601 ccatttgaca aaggccgaca agtgggccaa ggtctggatg catggtacaa aggtcatgtc
     3661 aaactgttga gcataggctt cgatttcctg caactcctct gctgaataag ctccacggaa
     3721 atagccaaag taaggctgtc cttcaatctg gtaagtgtct tccatgtaaa gctcaaaggt
     3781 tgagtagccc atgagagcca agacctcaat catctgcttg gcagaagcga cattcagcac
     3841 cgcatttcga gaacagtcaa ccatgtaagc caaatcttcg taagctgctt gttcctcaat
     3901 ctctacttta tcagcttctg ctagaactgt tgccaacaag gacaaggcac gataaagttg
     3961 gtgaggtttg cggtaggtca attgatagtg accttcctca ccctcgatag agatagaggc
     4021 ttggtcagac tgagtgacag ccacttccac atctggtaga gaaatgtgac cttttaaaac
     4081 ctcaatagct tgcgtttgtt tgggactaag tcctataaat cttaccattg cttttcctcc
     4141 tgtagccagt tgacaagggc accgtagaga ttggcatctg cgtgataggt gcaggcctgg
     4201 ataactggtg cgaccgtgta ttcttcgtag gcatcgacaa agttatcaac agccttcttg
     4261 acaccttgga taaaatctgg attttgactg atagagccac ccagactgat gacatctgga
     4321 tcgatcagat actgaatatt gagcaagcct tgcgccagat tgcggttcat gcgctcaatg
     4381 gcttcttgac aaagagcatt accagttgcg gcctcttggt aaatcttgcg accgtcccaa
     4441 tcagtatgac cagatttttc aataacgtat cgtaccatat tcccagttga tgctagttgc
     4501 gaccagttat taagtttttc agcaggggca agggttgtca tgtaaccaaa ttctccaccc
     4561 agaccgtggc gacctcgatg aagtctacca ttgataatca tggctccgcc aatccctgtc
     4621 ccaatcacga cacaggctgc attttcaagc tctggatgag ctagtagttc actgactcca
     4681 acgcagttgg catcattttc taaatggaca ggtagctgat aagagctaag cgcctcatac
     4741 caagaaaagc catggatgta gggcaccgca ctgaagccat caatcacacc tgtctcttga
     4801 ttgaccgcac ctggaacgct catagcaatc ccactgtaat cctgttctga caagcgttga
     4861 tctagccacg ctagtaaatc ctccaagttt tcaggcgttg aaatacttgt cttatccagt
     4921 attttcccat caggagtcag actggcaaac ttaatcccag tccctccgat atcaatcgtt
     4981 gcaatggtca ttgtttttac cataaaaagg ggcgaatcag cagttagttc ttactttttc
     5041 gcccctcctt tcttttgatg tttacttttt gaaattaaat ttcttctttt ttgatgaatt
     5101 ctgtacgaat ctcttgtgga gccaatagtc ctgaatgaac tggatatggt cgctcaagta
     5161 agtcaagaat ggtttgttga tgttctgata tgcgcacatt ttcttgactc atattatagt
     5221 aacggaggac atagccttct tcattttccg ccactttaaa ggctgttgga caaacttgcg
     5281 gtatgctgag aacagaatgg ctcaagaggc taccagtcgc aaccacgctt ccttcctgtc
     5341 tagcaagctg aaggctggta aacggtgtct gcaaggcttt ggcacgacga taggctgaga
     5401 agcgttcttg ggcttggtgg cattcaatcg caaattcgac ttcaaactca cgcaagcatt
     5461 gtgcttctgg cgttgggaag tagccccagt cacctagctc acctgatgca cgcaaaatgg
     5521 tcacggcaat ggtgttatcc ccaaggattt cgtattcatt caatcccttg ttggatacag
     5581 tcaccccttt ttcatcgtca tacagactga caaaagcttg ttggtgttga ggattttcag
     5641 gattttccca tgaagcagct ggtttgtttg gtcgtgtcac cacctcatag atactttcag
     5701 aatcattgct tggacgcgtg ttatgagtct tgaccaagag acggatacgg tgatccttgg
     5761 cagtgttagt aaagcgagtc ttgaagcgga tttgtggatt gtcaacaaag acaatcaact
     5821 cagtttccag aggaatgttt gtcaattctt ctgaccgtcc agcctcacgc ttcataaact
     5881 cgatgatacc ttgttgctct tcttctagct tttcatccgc actgacaggc acggtcaatt
     5941 catgtttgag caagatttta gcatagcgat ctgtgttttc caagacctcg tggcccttaa
     6001 gctctgcaaa gattggctct gttccttttg gttggaaata gatatactcg tttccgatgt
     6061 ccccacggtc ttcgaagcgg ataaagtctt cataggcttc gtgagttgtc ttgtcatata
     6121 ctgtgatatt gtcatccaca ctcaccgtta cgaatggtgt atcaatcact ccgttttggt
     6181 aaataccctc acggtgttct tgttttcctt ccagcaattg gaaggttgtc caagaaagcg
     6241 gcgctaggtg aactggaatg gtcacgcgca cttgtcgagc aatacgagct tggcggaact
     6301 tgtcttttgg taaatcgtac tcaaaattag ctccgaggtc ttcgattgta gcctctacag
     6361 gacgaccatc caagtcctcc acacggtaac ttggtaagat aagagcagcc atctttttgt
     6421 agccttctgt tgggtgcaat tccttgaaat cacaagtcgc cacatcaatc actgtgctga
     6481 cagtatcgac cttatcatgc aagcctgtgt taatgacagt aaagagatag tcactttgag
     6541 ccttatccgt agcaatttta cccttccact cgttgagcaa gttactttta acaaagtttc
     6601 ctacttggtt gaccttggca aaacgcgttt ccatctcgcg gtgaacttcg tccacgctac
     6661 agccacagat actatcatgt ggcgcattct gcaaaagtgt tttccaagca taggtcaact
     6721 ggtccttgtg gttgtgtcca ccagtgataa tagtcaaggg ttctaccact tgctctagga
     6781 ggttgctatt ttcttggaag gcttgtttta ggtaaatgcg ggatgaagaa gtgttggcaa
     6841 gtgtgtacca gccatctgtt tcctgactgg tcaactcgcc tgtaacagtt gataagtgtt
     6901 caggaagcgc accttctaca gcttgaacat attcatcaaa agaactatga acaaagatta
     6961 catccgggaa gagttcattt gccacacgaa tggcttcgct cagatttttc tgtacaggct
     7021 ggtggtcaca gccgttcatc atcaaccatt ggttggtcga agcgtaggca cgcacatctg
     7081 acaatttttg tttccagaag gtcaaggcct catctttgtc aactgggatt tcattcccat
     7141 tactgtacca gttggcaaag agaataccta aaacacgact accatccaca ccctgccagt
     7201 acatttctga aaactgggat gtaaaccgct catcttcaag gacttggttg tcaaatccaa
     7261 tcggcttcac accacgacca aaggctgcca cgtgaatacc tgatttttga aggatttgag
     7321 gagcttgtcc catatttcca aaggtatctg gaaagtagcc aatctgggtt gatttacccc
     7381 atttggcagc ttcttgttga ccaatcaagg tattgcggac attggcttca ctggagatca
     7441 agtagtcatc ctgcaagatg taaaagggac caattttaag tttgccctcg tcaatgtagc
     7501 gttggacctt gtcacgattt tcagggcgaa tttgtaagta gtcatcaagg acaatagttt
     7561 gtccatccaa gtggaaactc ttgaactcag ggtcattttc aaagagatca aagagattgt
     7621 caaacaattc caccaactgc atacgatggc tttcaaaagg caagtaccac tcacggtccc
     7681 agtgactatg tgagataata tgtacaacaa cattttccat gaagtaaaac ctcattctaa
     7741 atttaaattt taacgtttta aatgtaaact tgtgattctg ataagaatcg gttgagctaa
     7801 agcgagcccc ttagcgaata tccaagtaat ccaagaccaa ctcacagaac atcatgttag
     7861 cccaggagaa ccattcacga gagtagaggg tcggatcatc tacgtggaag ctttcgtgca
     7921 tgacacctgt accaccatcg caggcaacca gctgatccag caagaatttt ttctctgcct
     7981 tatctcttgt tgtcaatcct tggatagaaa gggcgattgg ccagatatag cgatagaagg
     8041 tatgagaact tccgagaccg ctagcgtatt ctccttggta gaagtatgga ttttcagagc
     8101 tcaaaatggt acgacgagta gcttgataca cttcatcgtt gacatcgcag tagcccagat
     8161 agggcgcagc tagtagactt ggtacatttg gatcatccat gatgctggca tttcctaggc
     8221 catccacttc aaaagcgtaa atcttttcgc ccttgctgtt ggtggtgtaa gcgtagtttt
     8281 cgattccttc ttggatttca tcctgaagac gcttggcatc agcaataaca ctctggctat
     8341 cagctaggtt taatgctgcg aagatttctt gcacataacc caagactact acagcaaaca
     8401 tatttgacgg aatcaagtaa ctatactgac agcagtcatc gctcggacga aaggctgacc
     8461 aagtcattcc tgtcactgca aaatcaggtc caaagccatc atttaccaag gtgtcttcct
     8521 tgcggtccgt atctcggaca aaacgataag gagagttctt gtggtcttgt tccaccgtcc
     8581 acagatggag aatttcctta gtcgctgcga caaaagtctc atcaaactga ctagtctcgc
     8641 cagtttcttt ccagaggaga taagccaact gcaaaggata gcaaagcgag tccacctcat
     8701 acttgcgttc ccagatccag ccgttaaggt ctgtgtggtc agtctcgtgg tgccctttcc
     8761 agttcttctc aatgttgaag gagttagcat agggatcctt gagtaccaag gtcatctgac
     8821 gtttgaccaa acctgcaatg gtctgacgca ggagggaatc tcttttagct acatgaaggt
     8881 agggtctgag ttgggctgtc gaatctcgaa gccacatggc aggaatatcc ccagtcaaga
     8941 caaaagttga accatcttct aagatttcaa ccgtattgtc caaggtatcg gtgtagcaac
     9001 gctcaaagac atcaacccac tctggatggt ccttggcccg ctctgctact tcatctagcc
     9061 attctctaac aatttctttc gaataaatca tcgtgcaatt ccctctttca aacaagtttc
     9121 atgttcagta tatagctttt gagacagaaa atacatacac aaatgatagt catttttcta
     9181 caaaatagtt atctttaaaa ctccttttct aaaggccctc tttttctgat ataatgtaga
     9241 aaaacagcta aaggaaagac tatgaaacca ctacttgaaa ccatcgatac ccgctttggt
     9301 actgctagca agcatgcctt ctctcgggga aataccctgc catacacagg cgtgcctttt
     9361 gggatgaatt attttgtgcc ccagaccagt gaccaggacg gagcttggtt cttcgatccg
     9421 catctgccta tctttcaggg gattcgatta actcaccagc ccagtccttg gattggggac
     9481 tactcttggc tccttctgac acctgtcacc agtcaactgg gtgaagacag tctctttcac
     9541 cgccagtctt cttatgatat agataaagct tgcttccaac ctcactattt gaagctcttt
     9601 tctctgcgtt atcagattga aacccagctc acaccgactt gctatggtac ttctattcgt
     9661 ttgaagcaaa agcaaggcaa agccctctcc ctctatcttc acgcagcaga tgaactgacc
     9721 gtagagcaag tagataagcg gactcttgcc ctgcgacaag aaggtaaaac tgaaactaac
     9781 aaaaattcgc taacgatgtt cactgccctg caaatgaaca cggatattct tgctatcagc
     9841 caagaagctg gggactggcg aattgactta gcaagtagtc aaaccgagat gcaactagcc
     9901 acttctttca tctctccttc tcaagctcta atcaatctac ctcaagaaga ttttgatagc
     9961 tgtaaatcaa gtgcccaagt ggattgggaa aatctcctcc atcgttttga cattatagag
    10021 acaggagagg ctgaccgaac cttctttgac cactgcctct acagactctt cctcttccca
    10081 cagacttttt atgagattaa tgaatcaggg caagccatcc acatggatct ggctactggt
    10141 actgtcaagc ctggtgtcct ctttagcaac aatggtttct gggatacctt ccgcaccacc
    10201 ttccccctct ttgcccttat cataccggag cactatcaac gctttttaga aggtttcctc
    10261 aatagctacc gcgatactgg tttccttcca aaatggctgg ctccagatga acggggtatg
    10321 atgccaggta cacttttaga cggtattatc gcagatagcg cctgcaagga catgaccccc
    10381 gacctagaag gagaactctt ccaagccatg ctcgaaacag ccagcaaagc cgaccctctc
    10441 ggcatcaatg gccgccacgg actagcccaa taccaagaac taggttacct ctctaccgac
    10501 caccacgaaa gtgttagcca tactctagac tatgcctata gtgacttttg tatcgccagc
    10561 tgtgccaaaa aactagagaa catagaaatc gctgaaacct acaaggctgc ttcacaaaat
    10621 taccgccagc tatttgacgc tgagacaggt tacatgcgag cacgagacaa tcaaggaaac
    10681 tttcaccctg acttctctcc ttatagttgg gggcgagact acgctgaatg ctctgccatt
    10741 caagctactt taggcgttct ccacgacatc cctggcttaa tccaactgat gggtggaaaa
    10801 gaaaccttta gcaactatct tttgaaagcc tgtcaagatg ctcccctctt tgaaataaca
    10861 ggctatggtt acgaaattca cgaaatgagc gagatggcta ctgctccttt tggacaaata
    10921 gccatttcca accagcctag tttccacatt ccttatctct tccgttacag cgattaccct
    10981 gactacactg cccttcttat caagacgctc cgtcagaaag cttttcaccc aagttgggaa
    11041 gcctatcctg gagatgaaga caatggtagt ctctctgctt ggtacatctg gtcagctctc
    11101 ggattttatc caacctgtcc aggaaaacca agctatgacc tcggaatccc tctctttgac
    11161 catctacgag tctacctagc taaagaagat aaatggctgg atatccatac taaacaaaac
    11221 cacaaccatt ttaactttgt caaagaatgc cgactggaca aaacactcgt atcaactatt
    11281 caacaccaag acctcttaaa agctgaacaa ctaactttca ccctcagctg gttaccaagt
    11341 cactaataac caaaagaacc tttgcatcgc gcaaaggttc ttcttttatg aaacttgaac
    11401 ttgaagttga tccacaagct gaccatccac cgttaggttc agatagaaat ccaaggtttt
    11461 atctcctgcg aaatacaagg ttggtagcgt cagacttttt tcagtctcac cagcttgaaa
    11521 cgcaagaact tgaatctcat cctgataggc gacaccatgg acacctgtcc ccggttgaat
    11581 cgaaatctta gcttctaaag gaccactaca ttctctgcgc ttaactgtaa aataggcatt
    11641 ttctcccttt gccacagcta ggcttttttc tgcaaatgct agttcctgaa caacttcttt
    11701 ttttgataat ccaggagttt tataaagaga aatcttggtc aatacaggga tagattgtgc
    11761 ctcggtaatc atcacgcgca ccttttgtgc ctctactagc ggacctcgca agaggcgctt
    11821 atgaccaact gtgaagcccc tgccaaactc ctgccagaca ccatccacct ctacttgcac
    11881 atgaaaagca gcgattcgtt gccctagctt caaatcttct cttaactcaa ttacatcaaa
    11941 agttttagga gaacctaaat cgagttctaa ctggatgggc aagtctgcat cgcttgccca
    12001 agagctggtc tcaaggccgt ctgtcaaatg gcgataagca aagtctgcgg aaagagttgg
    12061 accagatacc tcagctccca gagccaaatc ttctttatag agctcattgc gataggtcgc
    12121 aaattcataa agtcgttcaa tatcctttgc atcaaagagc ccagcttgat tcggcggaat
    12181 attaagcaag agtggagttc ctcgccctac tgagtgaaag tagatttcga ccaactcctc
    12241 gagagactta ggatcctgat cctcatggta gaaccagcct ggacggatgg aaacatctgc
    12301 ctctccgatt gaaaaaatcg tgcccgaggg atccccgtgc tgaagatagt ccagctctgc
    12361 ttctgttcct agtttatcag gattcacctt ttgccacagt ggatcacctg cataccctcg
    12421 ttcattgcca atccatcgga tactggtgcc ttctgttgaa aaaatcaagc aattgccctg
    12481 caggtcacga atggtttcaa accatttttc aaattcataa ttaacctttt gcgcgccctc
    12541 tcctctggca ccatccatcc aaacctcagc aaatttccct ccatttccat aggcaggatt
    12601 tgataagatt tccttcagct gagccagata ataggcattg tagtccgctt ctcggtccac
    12661 atgatagagg ggactatggg catcccacgg tgacaggtag acccccatat ccatatcaaa
    12721 ctctgtggca gcttgggata cttcaaggag caagtcgccc tttcctctcc tccaaggact
    12781 gaccttaacc gaataatctg tgtgagctgt cggataaagg acaaagccat cgtggtgctt
    12841 gaccaccaaa atcaactttt tgaagcccgt ttccttgagc acacgaaccc actcacgcgc
    12901 atccaactga ctcgggttaa agcgctcagg atcctcctgt ccagtccccc attcttggtc
    12961 ataaaaggta ttaggaccga agtggataaa agctgctagt tcatctccca gataagctag
    13021 ctgagtctga cttggtaacg gtccatgcgg tttgattttc ttcatcgtta tatatctcct
    13081 tcttttgcaa cttctcttgt tcacaaggtt atccacaggt tgtggataat aaaccatgat
    13141 ctaacagcca gctctttcca actccaactg gtaggctcag gatttttctc ctcaatgttc
    13201 cctcttcaaa cagctctgtc atatggttct gctaacacct ctcagaatgc tactctccat
    13261 aattattctc aggcttcttt caggtcattg tgtgaagacc attcactctc cagacttttc
    13321 cacagattgt gaataagtga ttattctaag ctatcacctc gtcgactata acaaaaaata
    13381 aaaagagggt caataagata attatctctt cctaaatact cagaaaagat tctataattt
    13441 gtacaattga acaagaaatg cttctccaaa atctatcttc aaaagaatgt tgcatctttt
    13501 tatcctttca cacaaacatt tctctttata cagatccaag tgataaccag atgataattg
    13561 gacacttttt ggtcatttgt atattttttg aaaaattttt taaaaaaatt ttatatcctt
    13621 tttatagaa
//
LOCUS       DAVKAU010000049        13400 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVKAU010000049 DAVKAU010000000
VERSION     DAVKAU010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.049"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            167..823
                     /locus_tag="VWX48_001658"
     CDS             167..823
                     /locus_tag="VWX48_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU9172246.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            813..1136
                     /locus_tag="VWX48_001659"
     CDS             813..1136
                     /locus_tag="VWX48_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU9172247.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1240..2070
                     /locus_tag="VWX48_001660"
     CDS             1240..2070
                     /locus_tag="VWX48_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9172248.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2224..3078
                     /locus_tag="VWX48_001661"
     CDS             2224..3078
                     /locus_tag="VWX48_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9172249.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3178..4551
                     /locus_tag="VWX48_001662"
     CDS             3178..4551
                     /locus_tag="VWX48_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU9172250.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4544..5605
                     /locus_tag="VWX48_001663"
     CDS             4544..5605
                     /locus_tag="VWX48_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU9172251.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5607..6299
                     /locus_tag="VWX48_001664"
     CDS             5607..6299
                     /locus_tag="VWX48_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9172252.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6328..6897)
                     /locus_tag="VWX48_001665"
     CDS             complement(6328..6897)
                     /locus_tag="VWX48_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9172253.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPHFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7032..7646
                     /locus_tag="VWX48_001666"
     CDS             7032..7646
                     /locus_tag="VWX48_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9172254.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7648..9294
                     /locus_tag="VWX48_001667"
     CDS             7648..9294
                     /locus_tag="VWX48_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9172255.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKLAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9306..10592
                     /locus_tag="VWX48_001668"
     CDS             9306..10592
                     /locus_tag="VWX48_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9172256.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFDQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10644..11177
                     /locus_tag="VWX48_001669"
     CDS             10644..11177
                     /locus_tag="VWX48_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9172257.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11255..11725
                     /gene="nrdI"
                     /locus_tag="VWX48_001670"
     CDS             11255..11725
                     /gene="nrdI"
                     /locus_tag="VWX48_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU9172258.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12018..13280)
                     /locus_tag="VWX48_001671"
     CDS             complement(12018..13280)
                     /locus_tag="VWX48_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU9172259.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3915 a         2510 c         3085 g         3890 t
ORIGIN      
        1 gtgttttgag ctgacttcat cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
       61 tgaggctagt ttcctagttt gctctttgat tttcattgag tattattaag acaatatgag
      121 gagaaagatg aaagaaaaag gattttagga gggggcgcag gcagccatgc caacggctct
      181 tggctatgtc agtatcggcc tggcctgtgg gactatcggt gcgccctatg tgacacctgt
      241 tgagatgggc ttgatgagtc tctttgttta tgctgggagt gcccagtttg ccatgttggc
      301 actgattgtg gttcaagctc ctgtggcagc tattgctatg acggtttttc taatcaactt
      361 gcgtctcttt ttgttgagtt tacacgcatc gacttatttc cgtcatacca gtctttggta
      421 caatatcggt atgtctagta tcttgacaga tgagacctat ggcgttttga tgggtgaatt
      481 ggcccataca gacaaggtaa atcctatgtg gatgcacgga aacaatctta acagctatgt
      541 ggcttggttt gtggggacag tagtcggaac ggctctgggt ggcctgctac caaatccaga
      601 aatctttggc ttggattttg ccctggttgg gatgtttatt ggtatttttg cttcgcaatt
      661 tcagattatg caaagacgga ttcctgtccg caatctgctc attatcctag cagttgttgc
      721 ggtgtccttc tttttgctct tgacagtggt gtctcagtca ctagctgttc tgtttgcgac
      781 gctacttggt tgtagcatgg gggtggtttt agatggtcag taagtatctt ttattagcag
      841 ttattttctc tggcttggtg acttggattc tccgtatgat tcccttcatc ttagtcaagt
      901 ataagggctt gcctgcaatc gttgagcgtt ttttgaagtt cttgcccgtt tccattatct
      961 ttgccttgat tctttcaagc gtagtgacag gtaaggttgg gagccttcct caaattaaat
     1021 ggctagactt cttagccgtc tttccaacag cttgggtagc ctttcgctac cgcaatctag
     1081 tcggaacagt tctctttgga gtggtcttga ttgccatctt gcgtttggtc ttttaaatta
     1141 cccataaaaa aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc
     1201 tgttaagatt ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac
     1261 tcatctcttg ctgccctagg acttgttgct gcaggtgtgc ttgcggcttg ctcagggggt
     1321 gctaagaaag aaggagaagc agctagcaag aaagaaatca tcgttgcaac caatggatca
     1381 ccaaggccat ttatctatga agaaaatggc gaattgactg gttacgagat tgaagtcgtt
     1441 cgcgctatct ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac agaatggtca
     1501 ggtgtctttg ctggtcttga cgctgaccgt tacaatatgg ctgtcaacaa tcttagctac
     1561 actaaagaac gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc
     1621 cttgtcgtga agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg
     1681 acggaagtcg ttcaagccac tacatcagct aagcagttag aagcatacaa cgctgaacac
     1741 acggacaacc caactatcct taactatact aaggcagatt tccaacaaat catggtacgt
     1801 ttgagcgatg gacaatttga ctataagatt tttgataaaa tcggtgttga aacagttatc
     1861 aagaaccaag gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac
     1921 gtttacccac ttcttgctca aggtcaagat gagttgaaat catttgtaga caaacgcatt
     1981 aaagaactct acaaagacgg aacgcttgaa aaattgtcta aacaattctt cggagatact
     2041 tatctaccag cagaggctga tattaaataa tttcttgaaa tcatccattc tgagtaagat
     2101 gggtgatttc tcagttttta gggatatagt tttaaactat atatctgatt atctaataac
     2161 aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga
     2221 atcatgaaaa tcaaaaaatg gcttggccta gtagcccttg ctacagtcgc aggtttggct
     2281 cttgcagctt gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca
     2341 actgttaacc gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa
     2401 aaagacggaa ttaccttgga atttacagag ttcacagact actcacaacc aaacaaagca
     2461 actgctgatg gcgaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg
     2521 aacaaagaaa acggaaaaga ccttgtagcg attgcagata cttacatctc tccaatccgc
     2581 ctttactcag gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca
     2641 aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt
     2701 caatcagctg gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac
     2761 atcaaagaaa atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt
     2821 tcattgtcat cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg
     2881 gactacaaga aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac
     2941 atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta
     3001 atcgcagctt accacacaga tgacgtgaaa aaagttatcg aagaatcatc agacggtttg
     3061 gatcaaccag tttggtaata agaaacaggg aggtgggaga gagaattcca cctcttgctt
     3121 ttgtatagag cacggagtgt aaagaagact attcgttcat agaaaggtag agagaatatg
     3181 gtttttccta gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agcccagcat
     3241 tattttgagg ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga
     3301 ctcaaggaag tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag
     3361 attgatgaga gctatacagc gccctttgtc atggcacatt tcaagagttc gcgtccagat
     3421 gccaagacct tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc
     3481 tggacagagg atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggagtt
     3541 gatgacgaca agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcac
     3601 catgatgatt tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca
     3661 acagacctag ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg
     3721 gtctgggaac aagggaccaa aaatgccttg gaacagctgg aaatttctgg tggcaataag
     3781 gggattgtga cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat
     3841 ggtggtgttg tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct
     3901 gcggatggcc gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga
     3961 gaaatggcct tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat
     4021 ggattggagt tgcctctctt acaggaggag cggatggcct ttctaaaacg tttctttttc
     4081 gagccagcgc ttaatatcga aggaatccag tctggttatc aaggtcaggg tgttaagact
     4141 attttacctg cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg
     4201 catgatgttc tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa
     4261 ttatactata ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc
     4321 aatgtgatcg agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca
     4381 gcggggacag gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc
     4441 ggtctaggaa atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat
     4501 tattacaccc atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat
     4561 caagttagat cagatcgatg tgacttttca ccaaaagaag agaaccatta cagcggttaa
     4621 ggatgtgacc attcacatcc aagaagggga tatctacgga atcgttggat attctggagc
     4681 agggaaatca acccttgtac gggtgattaa tctcttgcaa aaaccatctg cagggaaaat
     4741 taccattgac gacgatgtga tttttgacgg caaggtgacc ttgacggcag agcagttgcg
     4801 tcgtaaacgt caagatatcg gaatgatttt ccagcatttt aacctgatga gccaaaagac
     4861 agcagaggag aatgtagcct ttgcccttaa acactctgaa ctcagcaagg aagaaaagaa
     4921 ggctaaagta gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc
     4981 ttcacaacta tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga
     5041 tccaaaaatc ttgatttcag acgagtcaac ttctgccctt gatccgaaga caaccaagca
     5101 gattttggcc ttgttgcaag atttgaacca aaaattaggc ttgactgttg tcttgattac
     5161 gcatgaaatg cagattgtca aagacattgc caaccgtgtg gcggttatgc aggatgggca
     5221 tttgattgaa gagggtagtg tgcttgaaat cttctcagac cctaaacaac ctttgactca
     5281 agactttatc tcaacagcta caggtattga cgaagccatg gtcaaaatcg agaagcaaga
     5341 aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc
     5401 aacagacgag ccacttttga atgaattgta caagcattac caagtaatgg ctaatattct
     5461 ctatgggaat atcgaaattc tcgatggtac tcctgttgga gaattggtgg tggtcttgtc
     5521 aggtgaaaaa gcagcgttgg caggtgccca agaagccatt cgtcaagcag gtgtacaact
     5581 aaaagtattg aagggagtac agtaagatgg aatcattgat tcaaacctat ttaccaaatg
     5641 tctataaaat gggttgggct ggtcaggcag gctggggaac ggctatctac ttaactcttt
     5701 atatgacagt tctttccttt atcatcggag gcttcttggg gctagtggca ggtcttttcc
     5761 ttgtcttgac agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca
     5821 aaattacctc aatttttcgt gcggttccct ttatcatcct cttggcaatc ttgtcaccac
     5881 tttctcactt gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt
     5941 ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg
     6001 gtgtcattga ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc
     6061 tatcagaagg tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg
     6121 gggaaacagc tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt
     6181 atggatttaa ccgctacaat cacgatgtga ccatcttggc aaccattatt atcattttga
     6241 ttatctttgc aatccaattc ttgggagatt tcttgactaa gaaattgagt cataaataaa
     6301 aagagccgcg tggctctttt taactgatca gattttctgg gcaaattttt tactcaaggc
     6361 ttgtccaatc aaggcaccca ctagggctcc gatgacaata cttgcgataa atagaaggac
     6421 agttccaggg tttggagcga ccatgatacg gtcgatatat tcttgggatt ttcctcttgc
     6481 cagaagagta gccatatagg ctttgggcgc aatccacata agcaagattg gtcctgttgt
     6541 actaaaggcg aaaataatga aagaaaggaa gttctttgtt ttgtccttgt attttcctaa
     6601 atgagctact ccatctgcta ggaggccaca gataattcca ggaaggaagg aaccagcacc
     6661 gtgtttagtt cccaagaaaa agagggcaat gacaaggccg atagtggtaa tggctccaaa
     6721 gtgcggaact tttgcgacta ggatcatata gacgctaccg ccgacaaggg cagtaaaggc
     6781 aggcgcataa aacatgtttc cagtttggtc aaagagattg cccaaaagga caccaatccc
     6841 catgcagagg aagtaaagaa ctgcaaaaag cagtgtagtt aagatagatt tcttcatgaa
     6901 ttgtctcctg ataatttttt cacaattctc attttaccat ggtttggtgg gattgtaaat
     6961 ggatactaga agtttttgaa aacgcttgaa atatgatata atggtttcat agttattttt
     7021 aggggaatat catgggtaga tttttagact ttgtctttaa tcgtttcttt ttagggatga
     7081 ttgcgacagc cttcttttgg ctattaactt tagcaggagg gattatcctt ggtctagcgc
     7141 cggctagtgc caccttgatg agcttatatg cagaacatgg ttatagcttt cgggaataca
     7201 gtttgaagga ggcttggtct ctttacaagc aaaattttgt ctcaagcaac ctgattttct
     7261 atagcttttt aggtgtgggt ctagttttga cctatggttt gtatctcttg gtgcaattgc
     7321 ctcatcagac cattgttcat ttgattgcga cccttttgaa tgtcctagta gttgccctga
     7381 tctttttggc ttatacagta tctttaaaat tacaagttta ttttgccttg tcctatcgaa
     7441 atagtctcaa attatccttg attggcatct ttatgagtct agcagctgtg gccaaggttc
     7501 tccttgggac tgtgctactt gtagcaattg gttactatat gcctgccctg ctattttttg
     7561 taggaattgg gatgtggcat ttctttatca gtgatatgtt ggaacctgtc tatgaaatca
     7621 tccatgaaaa attggcgaca aaatagaatg aagcactttt ggctacatac gcttctaaga
     7681 acctatagtt cagtgatgat cattatcatt gcgagttttg caatcttact ctcttacgct
     7741 gactgggatt cacgtgaaaa ggaagcccag agagtagccc agcgtgtaac tgctagaaca
     7801 gtgagtgaaa ttgaatatta ccatagagag tcaacccaga tagctcaggc tttagttgaa
     7861 aatcaagctc gtattgaggg aatctataaa tactttagcc ttagcatgcc agactatttt
     7921 tactggcaat tagagcggaa agcttcgcct tatatatcag tctctctgta tgaaaatgtt
     7981 gatgacctct atgttcgaaa tgattttgta actggagtgg ccattgcttt tcaagattac
     8041 aaggaagtct atgtttctac taaagacaaa cgtagtggag aaaaaatcag ggctgaggat
     8101 ttcaaactag caggaaatag ttttgccatt ccagtgtcag atccagtgtc agatcaagac
     8161 ttaggagtga tttacatctc cttggatcct gctgttttat accatgccat tgataatact
     8221 agaggtcata ctccgatggc agtaacagtg acctcacctt ttgatacgga gatttttcat
     8281 attggtgaga cagttgataa ggagagtgaa aattggctag ttggcttaac ttctcatggt
     8341 tatcaggttc aggtggcagt tcccaaaaac tttgttttac aaggaacggt gaccagctct
     8401 gctttgattg tgggcttgag ccttctcttt attgtcattc tttatctgac tttgaggcag
     8461 acctttgcta attatcaaaa gcaggtagtg gatttggtgg attccatcca agctattgcc
     8521 caaggacaag aaggtcttcg cattgatacg cttgaaaagg atcaggaatt gctcctaatc
     8581 gcggagacga ccaatgatat gttggatcga ttggaaaaga atatccatga tatttaccag
     8641 ttagaactca gtcaaaaaga tgccaatatg cgggccttgc aggcgcaaat caaccctcac
     8701 ttcatgtata atacgctgga gttcttgcgc atgtacgcag tcatgcagag tcaagatgag
     8761 ttggcagata tcatttatga attcagtagt ctcttgcgta acaatatttc cgacgaaaga
     8821 gagaccctcc tcaaacagga attagaattt tgccgtaaat acagctatct ctgcatggtt
     8881 cgctatccca agtccattgc ctatggtttc aagatagatc cagagttaga gaatatgaag
     8941 attcccaagt ttaccttgca accgctggta gaaaactatt tcgcgcatgg tgttgaccac
     9001 aggcggacag ataatgtgat tagcatcaag gctcttaaac aggatggttt tgtggaaatt
     9061 ttggtggtcg ataatggtag aggaatgtcg gctgaaaagt tggcaaatat ccgagaaaaa
     9121 ttaagtcaga gatattttga acaccaagcc agctacagtg atcaaaggca gtctatcggg
     9181 attgtcaatg tacacgagcg ttttgtgctc tattttggag accgctatgc cattacgata
     9241 gagtctgcag agcaagccgg tgttcagtat cgtattacaa ttcaagatga gtagaaaggg
     9301 agaaaatgta taaagtatta ttagtagatg atgagtacat ggtgacagaa ggtctgaagc
     9361 gtttgattcc ctttgataag tgggatatgg aggtcgtcgc aacagccagt catgccgatg
     9421 aagctctaga atatgttcag gaaaatcctg tcgatgtcat catttccgat gtcaatatgc
     9481 cagacaaaac agggcttgat atgattcggg agatgaaaga gatcttacca gatgctgcct
     9541 atatcctgct ctcaggttat caggagtttg attatgtaaa aagagcaatg aaccttagtg
     9601 tggtggacta tttggtcaag cctgttgata aggtagagct gggaaatctg ctggagaaga
     9661 ttgcaggtca gctcggcgag agagggaaga aaagtcagac tcttagtcaa gaattagacg
     9721 aggctggatt tgttagttat ttaggggata aggagaattg gtggataggt ctatccaagg
     9781 aaaaacaagg ttccttcgcc attccctact atgtcttggg ccaagactgg cagattttca
     9841 tttctgacca acccctagat ggtttagtcg ttacaccttt tgaagctcct tatcaagaac
     9901 actttgaacg ttggaagctg aatgctgaga aaaccctctt ttacggttct gtaaatctgc
     9961 agcagtctga gagtctcttt gcctattacg aaccgattta tagggttatc attcagggaa
    10021 atctcaatca aatcgtagaa gagttaaatc tcttggagaa ggtagttctt gaaaatacac
    10081 ctcgtgtttc gattactaaa cagcttttta tccagtttgt catggatgtt ttccatttat
    10141 ttgaacatct caaagctgat gatatgacgg acattgtcaa aaccattcat gctattcaat
    10201 ccttcgatga attggtttct tatatcaagg aaactctgat cagctttttc gatcaatacc
    10261 gtatgaatga aaatgtggtc agtgtgctgg aagtcattgg tcgtgattac caaaaagagc
    10321 tttccctcaa ggatatcagt aaggccctct ttatcaatcc tgtctatcta gggcagttga
    10381 ttaagcgtga aaccgattcg acctttgcag agttactaaa taaacaacgt attaaggctg
    10441 cccagcagct cttgctttca actagtgaca gcatcgaaga tatttgttat gctgttggtt
    10501 acagtaacct tggatatttc tataaagttt tccgaaaatt gtgcggaaaa tcgccaaaag
    10561 cctaccgaaa acaggtagaa actatactat aagatttgta ttcctttaca aaaggtgcta
    10621 taatattatc aggaggtcct atcatgaaaa agaaaccaat ttatctatgg gttttgctaa
    10681 tcttgtctgc ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta
    10741 aagaagccct tcgtgctgct cagaaacaag ttgcaggggt caatgctcag caattagaag
    10801 accagcttaa ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt
    10861 tgattgtgct atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt
    10921 tgcaatatgc aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt
    10981 atggctatgt tggtttacaa gacgctgtgc agttggttca agatgagagc atgcgtttga
    11041 cagtgagtat tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc
    11101 tagcccttgt cttctataag atgtggcgac aacagaaagc cttggcagaa gaagaggaaa
    11161 cagaagagct tacctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg
    11221 ttttttgatt atagataaaa tcatggaggt acatatgaag acaatttctt tagtttatat
    11281 tagtttgagt ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca
    11341 atacaaaggg attgaggttc aaaagattca tatcaaggat ttggtcaagg aaggcaaaaa
    11401 tttctatgaa atggaccatc cctatgtcgc ttttttgccg acctatctcg aaggtgggaa
    11461 tggcgtggat aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta
    11521 tggtaacaat gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa
    11581 ccaatactgc ctaacagcca agcaatacag tcaacgcttt ggcttccctg tattggctga
    11641 ctttgaaatg cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt
    11701 gtatgagttg gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct
    11761 agtcgcaggt tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag
    11821 agattctcga atagtataaa gttcttataa gaggtggttg aagttgttca actgtttttt
    11881 gagtataaac agtctttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt
    11941 cttatgcttt ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt
    12001 catctcgcgc ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg
    12061 gcgaagccaa agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga
    12121 tttttgtttt cacgcgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg
    12181 aaagagccaa tcatggcaaa gcggagcatg gttgaaacct gaccagcgaa gaacttgata
    12241 atgacgatac cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattgtcc
    12301 tctttttgac tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata
    12361 acagttataa ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac
    12421 cattcgccaa gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca
    12481 gcttcaaccg cctgccctgt aggatactga atcagtgctc ccagtgccac aaagaagacg
    12541 gctaggatag ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta
    12601 aagttgacgg tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata
    12661 ggagccggca tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt
    12721 gtcttctcga caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgca
    12781 agaacagtcg caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg
    12841 tagcctccaa agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta
    12901 atgctaagtc caatcattgg gaaagcactg gcgatgatag ctgagcacag aatggcaaca
    12961 ccagccgtgt tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt
    13021 tttccttttt cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca
    13081 ccaaaacgga aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac
    13141 caaccgtaag aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca
    13201 gttgccatta ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt
    13261 aaggaaatag cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata
    13321 tgtaatctat attctacaaa aaattttgga aaaatgcaag aatattttga aaaaagatag
    13381 aaaatttaca aagaaaatct
//
LOCUS       DAVKAU010000050        13341 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVKAU010000050 DAVKAU010000000
VERSION     DAVKAU010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13341
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.050"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(175..1806)
                     /locus_tag="VWX48_001672"
     CDS             complement(175..1806)
                     /locus_tag="VWX48_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU9172260.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2099..7009
                     /locus_tag="VWX48_001673"
     CDS             2099..7009
                     /locus_tag="VWX48_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU9172261.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPG
                     ATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGHEVSFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVLAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            7099..8295
                     /locus_tag="VWX48_001674"
     CDS             7099..8295
                     /locus_tag="VWX48_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU9172262.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8431..8958
                     /locus_tag="VWX48_001675"
     CDS             8431..8958
                     /locus_tag="VWX48_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9172263.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9035..9391
                     /gene="glnR"
                     /locus_tag="VWX48_001676"
     CDS             9035..9391
                     /gene="glnR"
                     /locus_tag="VWX48_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU9172264.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9428..10774
                     /gene="glnA"
                     /locus_tag="VWX48_001677"
     CDS             9428..10774
                     /gene="glnA"
                     /locus_tag="VWX48_001677"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU9172265.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10864..10983)
                     /locus_tag="VWX48_001678"
     CDS             complement(10864..10983)
                     /locus_tag="VWX48_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU9172266.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11528..12844
                     /locus_tag="VWX48_001679"
     CDS             11528..12844
                     /locus_tag="VWX48_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9172267.1"
                     /translation="MPDTWEWVRFSTLVEIVRGGSPRPIKDYLTSEVDGINWIKIGDT
                     EKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLTNSMSFGRPYILNVDGAIHDGWLAIS
                     NYENSLNKDYLFYILSSNVVYSQFLSLISGAVVKNLNSDKVASILIPLPPLAEQQRII
                     EAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDESVEVLL
                     EKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNSYYGNKDETTSYPIYEIPEAWRYIKF
                     ASLVNFRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDIS
                     PKGTLLMSFKLSIGKVAILDIPATHNEAIISIFPYAKENIIRDYLMIFLPLISTLGDS
                     KDAIKGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(12792..13337)
                     /locus_tag="VWX48_001680"
     CDS             complement(12792..13337)
                     /locus_tag="VWX48_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9172268.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT         4343 a         2387 c         2790 g         3821 t
ORIGIN      
        1 caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaaatag aggtgtacta
       61 ttctagtttc aatatactat atatctgcag aatactcttt cagtttcatt cagcctagtc
      121 ttgcttagga aaaagtaaga agccatccaa ttatgatgga tagcttcttg gttcttagat
      181 ttgttctgca aaaacctttt cagcaaggtt catagcgtgg tctgatacac gagtgtagtg
      241 tgagatgatg tcgataaagt tgaccccagc ttgtgttgaa cattcgcctt tgttgaggcg
      301 tttgatgtgg gtttttctga gaacacgttc tatcttattg attgcttcat gacgttctac
      361 aagactgcgt gctttttcaa tatcattgtt ttccacacta tccagagcat ctttgataaa
      421 gtcactagtt tggcggtaaa cttcctctaa ttctttcaag gcggcatcag aaaattcaac
      481 atttttccgt tgaagatagt cagtcagatt gagtagagcc tccgtgtggt ctccaatccg
      541 ttccaaatca cgggaggaat caaggatatt ggtgagcact tcactttctt tttggctgag
      601 agcttcgctt gaaagggcaa tgagataacg tgttaattgc tcatcgatgg tgttaattgc
      661 ttcttcggtt ttatgccctt tttcagcaac tttttcatcc aagtcaatga tgtacttata
      721 ggaaaggtca aaggctttag cagcgtagtt tcctaagtgc aagagctctt tcttagcatt
      781 tcctagagcg atagatgggg cctgtttgat gaaatgttca tcaagatata agggttcgta
      841 ttttacaacc tcgtcctctc caggaataat cttggttaca aagtaagcca gagctccgat
      901 aaatggaaat tggacaatgg tgttggtaat attaaaggtt ccgtgagcaa aggcgatggt
      961 catttccggt gctagattta gcgtagcttc aaaccaatga atcaggacag taaaaggaac
     1021 tagaaaaata acgcagacaa ctgttccgat aacgttgaag gcaacatgag ctcctgctac
     1081 ccgtttagct gcaatattag cccctaaaga ggcaatgatg gctgtaatgg ttgtcccgat
     1141 attgtcacca aatagaactg gcaaagctcc ctgtaggtca attagattgc cggcgtagag
     1201 gttttgtaaa atcccaatgg tagccgaaga agcttgaatt agcaaggtca agccagtacc
     1261 gacaaagaca cccaaaacag gatttttact tagctcaatc atatagtcct taaagacctg
     1321 taaatccttg agtggagcca ttgcgccgct catgagattg agggcaaaaa agataccacc
     1381 gacaccaaag aggatgcgtc cgatattatt gactgtccga tttttcgtaa aaaagagaca
     1441 gacggcaccg ataaagagca taggtagggc atagttacct aatttaaaac cgatgagaaa
     1501 ggatgtgaca gttgtcccaa tattagcacc catgacaatc ccgatagcct gacgtaaggt
     1561 taagagaccg gcactgacca ggccgactgt aataactgtt acaccagaac tagactgaat
     1621 tagagcagtc atcccaatac caaccagaac tccaaagaaa ggattactag tatatttgtc
     1681 aatgtaaaaa cgaaggcgat ctccagcagc ttgttgcaaa ccgtctccca tggtcttgat
     1741 gctatataag aatagcccca gaccacctaa aaagtgaaat aaaatttcct gccaattaat
     1801 ggacatttct ttttcctccg aaaaataatc gcggaatatc tcctattcta ttttaaagga
     1861 taaaagtaaa tctaacaagt gttaatgtca agtttgtaaa agaaaattat aattgataag
     1921 tgtattattt ttaagagttt ttaaccttat tttagatttg tgcaaacagt tattgttttt
     1981 tgtctaaaaa tgttttagga taaaaatgtg attatcatgg ttctagagtt tgataaaaaa
     2041 ctacagaata taaagcgctt tctttaaaac aacaaaatca atcttttagg aggagaaaat
     2101 gaagaatcca ttttttgaaa gacgttgtcg ttacagtatt cgtaagttat cagtaggagc
     2161 ctgctcgctg atgattggtg ctgttttatt tgctggtcca gccttggctg aagaaactgc
     2221 agttcctgaa aatagcggag ctaatacaga gcttgtttca ggagagagtg agcattcgac
     2281 caatgaagct gataagcaga atgaagggga acatgctaga gaaaacaagc tagaaaaggc
     2341 agaagcagct agcgcagcta aaccagagga aaaagcaggt gaggtggttg cagaaacacc
     2401 atctgcagaa gcaaaaccta agtctgacaa ggaaacagaa gcaaagcccg aagcaactaa
     2461 ccaaggggat gagtctaagc cagcagcaga agctaataag actgaaaaag aagtccagcc
     2521 agatgtccct aaaaatacag aaaaaacatt aaaaccaaag gaaatcaaat ttaattcttg
     2581 ggaagaattg ttaaaatggg aaccaggtgc tcgtgaagat gatgctatta accgcggatc
     2641 tgttgtcctc gcttcacgtc ggacaggtca tttagtcaat gaaaaagcta gcaaggaagc
     2701 aaaagttcaa gccttatcaa acaccaattc taaagcaaaa gaccatgctt ctgttggtgg
     2761 agaagagttc aaggcctatg cttttgacta ttggcaatat ctagattcaa tggtcttctg
     2821 ggaaggtctc gtaccaactc ctgacgttat tgatgcaggt caccgtaacg gggttcctgt
     2881 atacggtaca ctcttcttca actggtctaa tagtattgca gatcaagaaa gatttgctga
     2941 agctttgaag caagacgcag atggtagctt cccaattgcc cgtaaattgg tagacatggc
     3001 caagtattat ggctatgatg gctatttcat caaccaagaa acaactggag atttggttaa
     3061 acctcttgga gaaaagatgc gccagtttat gctctatagc aaggaatatg ctgctaaggt
     3121 aaaccatcca atcaagtatt cttggtatga tgccatgacc tataactatg gacgttacca
     3181 tcaagatggt ttgggagaat acaactacca attcatgcaa ccagaaggag ataaggttcc
     3241 ggcagataac ttctttgcta actttaactg ggataaggct aaaaatgatt acactattgc
     3301 aactgccaac tggattggtc gtaatcctta tgatgtattt gcaggtttgg aattgcaaca
     3361 gggtggttcc tacaagacaa aggttaagtg gaatgacatt ttagacgaaa atgggaaatt
     3421 gcgcctttct cttggtttat ttgccccaga taccattaca agtttaggaa aaactggtga
     3481 agattatcat aaaaatgaag atatcttctt tacaggttat caaggagacc ccactggcca
     3541 aaaaccaggt gacaaagatt ggtatggtat tgctaaccta gttgcggacc gtacgccagc
     3601 ggtaggtaat acttttacta cttcttttaa tacaggtcat ggtaaaaaat ggttcgtaga
     3661 tggtaaggtt tctaaggatt ctgagtggaa ttatcgttca gtatcaggtg ttcttccaac
     3721 atggcgctgg tggcagactt caacagggga aaaacttcgt gcagaatatg attttacaga
     3781 tgcctataat ggcggaaatt cccttaaatt ctctggtgat gtagctggta agacagatca
     3841 ggatgtgaga ctttattcta ctaagttaga agtaactgag aagaccaaac ttcgtgttgc
     3901 ccacaaggga ggaaaaggtt ctaaagttta tatggcattc tctacaactc cagactacaa
     3961 attcgatgat gcagatgcat ggaaagagct aaccctttct gacaactgga caaatgaaga
     4021 atttgatctc agctcactag cgggtaaaac catctatgca gtcaaactat ttttcgagca
     4081 tgaaggtgct gtaaaagatt atcagttcaa cctcggacaa ttaactatct cggacaatca
     4141 ccaagagcca caatcgccga caagcttttc tgtagtgaaa caatctctta aaaatgccca
     4201 agaagcggaa gcagttgtgc aatttaaagg caacaaggat gcagatttct atgaagttta
     4261 tgaaaaagat ggagacagct ggaaattact aactggctca tcttctacaa ctatttatct
     4321 accaaaagtt agccgctcag caagtgctca gggtacaact caagaactga aggttgtagc
     4381 agtcggtaaa aatggagttc gttcagaagc tgcaaccaca acctttgatt ggggtatgac
     4441 tgtaaaagat accagcctac caaaaccact agctgaaaat atcgttccag gtgcaacagt
     4501 tattgatagt actttcccta agactgaagg tggagaaggt attgaaggta tgttgaacgg
     4561 taccattact agcttgtcag ataaatggtc ttcagctcag ttgagtggta gtgtggatat
     4621 tcgtttgacc aagccacgta ccgttgttag atgggtcatg gatcatgcag gggctggtgg
     4681 tgagtctgtt aacgatggct tgatgaacac caaagacttt gacctttatt ataaagatgc
     4741 agatggtgag tggaagctag ctaaggaagt ccgtggtaac aaagcacacg tgacagatat
     4801 cactcttgat aaaccaatca ctgctcaaga ctggcgcttg aatgttgtca cttctgacaa
     4861 tggaactcca tggaaggcta ttcgtatcta taactggaaa atgtatgaaa agcttgatac
     4921 tgagagtgtc aatattccga tggccaaggc tgcagcccgt tctctaggca ataacaaggt
     4981 acaagttggc tttgcagatg taccggctgg agcaactatt accgtttatg ataatccaaa
     5041 ttctcaaact ccgcttgcaa ccttgaagag cgaagttgga ggagacctag caagtgcacc
     5101 attggatttg acaaatcaat ctggtcttct ttattatcgt acccagttgc caggcaagga
     5161 aattagtaat gtcctagcag tttccgttcc aaaagatgac agaagaatca agtcagtcag
     5221 cctagaaaca ggacctaaga aaacaagcta cgccgaaggg gaggatttgg accttagagg
     5281 tggtgttctt cgagttcagt atgaaggagg aactgaggac gaactcattc gcctaactca
     5341 cgcaggtgta tcagtatcag gttttgatac gcatcataag ggagaacaga atcttactct
     5401 ccaatatttg ggacaaccgg taaatgctaa tttgtcagtg actgtcactg gccaagacga
     5461 agcaagtccg aaaactattt tgggaattga agtaagtcag gaaccgaaaa aagattacct
     5521 agttggtgat agcttagact tgtctgaagg acgctttgca gtggcttata gcaatgacac
     5581 catggaagaa cattccttta ctgatgaggg agttgaaatt tctggttacg atgctcaaaa
     5641 gactggtcgt caaaccttga cgcttcatta ccaaggccat gaagttagct ttgatgtttt
     5701 ggtatctcca aaagcagcat tgaacgatga gtacctcaaa caaaaattag cagaagttga
     5761 agctgctaag aacaaggtgg tctataactt tgcttcatca gaagtaaaag aagccttctt
     5821 gaaagcaatt gaagcggccg aacaagtgtt gaaagaccat gaaactagca cccaagatca
     5881 agtcaatgac cgacttaata aattgacaga agctcataaa gctctgaatg gtcaagagaa
     5941 atttaaggaa gaaaagacag agcttgatcg tttaacaggt gaggttcaag aactcttggc
     6001 tgccaaacca aaccatcctt caggttctgc cctagctccg cttcttgaga aaaacaaggc
     6061 cttggttgaa aaagtagatt tgagtccaga agagcttgca acagcgaaac agagtctaaa
     6121 agatctggtt gctttattga aagaagacaa gccagcagtc ttttctgata gtaaaacagg
     6181 tgttgaagta cacttctcaa ataaagagaa gactgtcatc aagggtttga aagtagagcg
     6241 tgttcaagca agtgctgaag agaagaaata ctttgctgga gaagatgctc atgtctttga
     6301 aatagaaggt ttggatgaaa aaggtcaaga tgttgatctc tcttatgctt ctattgtgaa
     6361 aatcccaatt gaaaaagata agaaagttaa gaaagtattt ttcttacctg aaggcaaaga
     6421 ggcagtagaa ttggcttttg aacaaacgga tagtcatgtt atctttacag cacctcactt
     6481 tactcattat gcctttgttt atgaatctgc tgaaaaacca caacctgcta aaccagcacc
     6541 acaaaacaca gtccttccaa aacctactta tcaaccggct tctgatcaac aaaaggctcc
     6601 taaattggaa gttcaagagg aaaaggttgc ctttcatcgt caagagcatg aaaatgctga
     6661 gatgctagtt ggggaacaac gagtcatcat acagggacga gatggactgt taagacatgt
     6721 ctttgaagtt gatgaaaacg gtcagcgtcg tcttcgttca acagaagtca tccaagaagc
     6781 gattccagaa attgttgaaa ttggaacaaa agtaaaaaca gtactagcag tagtagctac
     6841 acaggaaaaa ccagctcaaa atacagcagt taaatcagaa gaagcaagca aacaattgcc
     6901 aaatacagga acagctgatg ctaatgaagc cctaatagca ggcttagcca gccttggtct
     6961 tgctagttta gccttgacct tgagacggaa aagagaagat aaagattaaa tatcgaaaaa
     7021 tcttgtgaaa tctttcctta tatttccaaa gtgtgatata atagtttcga ataaaataaa
     7081 taaaggagtt tttgtaacat ggcaaaactt actgttaaag acgttgactt gaaaggtaaa
     7141 aaagtcctcg ttcgtgttga cttcaacgta ccattgaaag atggcgtaat cactaacgat
     7201 aaccgtatca cagcagctct tccaactatt aagtacatca tcgaacaagg tggacgtgca
     7261 attcttttct ctcaccttgg acgtgtgaaa gaagaagctg ataaagctgg taaatcactt
     7321 gctcctgtag cagctgactt ggcagcaaaa cttggtcaag atgttgtttt cccaggtgtc
     7381 actcgtggtg ctgaattgga agcggcaatc aacgctcttg aagatggaca agttctcttg
     7441 gttgaaaaca ctcgttacga agatgttgac ggcaagaaag aatctaaaaa cgatcctgaa
     7501 cttggtaaat actgggcatc acttggagat ggtatcttcg taaacgatgc attcggtaca
     7561 gctcaccgtg cacacgcatc taatgttggt atctcagcaa acgttgaaaa agcagttgct
     7621 ggtttccttc ttgaaaatga aattgcctac atccaagaag cagttgaaac tccagaacgt
     7681 ccattcgtgg ctatccttgg tggttcaaaa gtttcagaca agatcggtgt tatcgaaaac
     7741 ttgcttgaaa aagctgataa agtccttatc ggtggtggga tgacttacac attctacaaa
     7801 gcacaaggta tcgaaatcgg taactcactt gtagaagaag acaaattgga tgttgcgaaa
     7861 gctcttcttg aaaaagcaaa tggtaaattg atcttgccag ttgactcaaa agaagctaac
     7921 gcatttgctg gttacactga agtgcgtgac actgaaggtg aagcagtttc tgaaggcttc
     7981 cttggtcttg acatcggtcc aaaatctatc gccaaatttg acgaagcttt gactggtgcc
     8041 aaaacagttg tatggaacgg acctatgggt gtatttgaaa acccagattt ccaagctggt
     8101 acaatcggtg tgatggacgc tatcgtgaaa caaccaggag ttaaatcaat catcggtggt
     8161 ggtgactcag ctgccgcagc gattaacctt ggccgtgcag acaagttctc atggattagt
     8221 acgggtggtg gagcatcaat ggaacttctt gaaggtaagg ttcttccagg acttgcagcc
     8281 ttgacagaaa aataagattt tataaacaaa tcaaagaaga gagggatgaa agttcctctt
     8341 ttcttttgct taaaataaaa acgcttcctc tcaactatta ctcataaaaa tcaccgattt
     8401 atgataaaat ggaaatagaa agttgagatt atgagttatt ttaaaaaata taaattcgat
     8461 aaatcccagt tcaaacttgg tatgcgaacc tttaaaacag gtattgctgt ttttctagtt
     8521 ctcttgattt ttggcttttt tggctggaaa ggtcttcaaa ttggtgcttt gacagccgtt
     8581 tttagcctga gggagagttt tgatgagagt gttcattttg ggacttcgcg tattctagga
     8641 aatagtatcg gtggactcta tgccttggtc ttcttcttat taaatacctt tttccacgaa
     8701 gccttttggg tgaccttggt agttgttcca atctgcacca tgttaaccat tatgacaaat
     8761 gtagccatga ataacaaagc aggggttatt ggtggtgtag cagctatgtt aatcattacc
     8821 ctatcaattc caagtggtga gacaatttcg tacgtgtttg tgcgtgtatc agaaacgttt
     8881 atgggagttt ttgtcgcaat tatcgtaaat tacgatattg atcgtattcg tctcttttta
     8941 gagaaaaaag aaaaataatg ttacatttta taacattatc aattgacgtt tgtctttttt
     9001 tagactataa tagacagaaa gaaggaaatt gtaaatgaag gaaaaagaat ttcgccgaaa
     9061 tatggctgtt tttcctatcg gcagtgttat gaagttgacc gatctatcgg cgcgtcagat
     9121 tcgttattat gaagatcaag agttgatcaa gcccgatcga aacgaaggaa atcgtcgcat
     9181 gtattccttg aatgacatgg atcgtctgct tgaaatcaaa gattatatct ctgaaggtta
     9241 taatatcgct gccattaaga aaaaatatgc tgaacgtgaa gcgaaatcca agaaagcggt
     9301 tagtcagact gaagtacgtc gtgcacttca caatgaactc ctccaacagg ggcgttttgc
     9361 ttcagtacag tcaccttttg gtcgcggtta ggcaaccgca agtagtcata gattaaggag
     9421 aaaacttatg ccaatcacag ctgcagatat tcgtcgtgaa gtcaaggaaa aaaatgttac
     9481 ctttattcgt cttatgttct cagatatttt gggaaccatg aaaaacgtcg aaattcctgc
     9541 tacagatgaa cagttagata aggtcttgtc gaacaaggtt atgtttgatg gatcttctat
     9601 tgaaggtttt gtacgtatca atgagtcgga tatgtacttg tacccggact tggatacatg
     9661 gacagtcttc ccttggggag atgaaaatgg aagtgttgca ggtctgatct gtgatgtcta
     9721 tacaacagaa ggtgaaccat ttgcgggtga ccctcgtggt aatttgaaac gagctcttcg
     9781 tcacatggaa gaagttggat tcaaatcctt caaccttggt ccagagccag aattcttcct
     9841 atttaagttg gatgaaaatg gggacccaac acttgaagtg aatgacaagg gtggctactt
     9901 tgatttggca cctactgacc ttgcggacaa cacacgtcgt gagattgtga atgtcttgac
     9961 caaaatggga tttgaagtag aagcgagtca ccacgaggtt gcggttggac agcatgagat
    10021 tgactttaag tacgatgaag ttctccgtgc ttgtgataag attcaaatct ttaaacttgt
    10081 tgttaaaacc attgctcgca aacacggact ttacgcaaca tttatggcga agccaaaatt
    10141 tggtattgct ggctcaggta tgcactgtaa tatgtccttg tttgatgcag aaggaaataa
    10201 cgccttcttt gatccaaatg atccaaaagg aatgcagttg tcagaaacag cttaccattt
    10261 cctaggcggt ttgatcaagc atgcttacaa ctatactgcc atcatgaacc caacagttaa
    10321 ctcatacaaa cgtttggttc caggttatga agcgcctgtt tacattgctt gggctggtcg
    10381 taaccgttcg ccacttgtgc gcgtacctgc ttcacgtggt atgggaactc gtcttgagtt
    10441 gcgttcagtg gatccaatgg cgaaccctta cattgctatg gctgttcttt tggaagttgg
    10501 tttgtatggt attgaaaata aaatcgaagc accagctcct atcgaagaaa atatctacat
    10561 catgacagca gaagagcgca aggaagctgg tattacagac cttccatcaa ctcttcataa
    10621 tgctttgaaa gctttgacag aagatgaagt ggttaaagct gctctcggag atcacatcta
    10681 cactagcttc cttgaagcca aacgaatcga atgggcaagt tatgcaacct tcgtttcaca
    10741 atgggaaatt gataattatt tagaccttta ctaatataga agaaagattg cctgtgggta
    10801 aacagtcaca cagcagtcta agccatcaaa tacctataac ccttaaaata gcgatttcgg
    10861 tcgctattta tttttcgaaa aatcctcttg actcttttgc gaattagatt tatcatcaga
    10921 cgtgtagaag aaaatcaagg agtcactatg gaaaaattca atttcaaaaa caatatcggg
    10981 caagaaaaca agttacttca aatcgaaatc tacaagttta ctaacttttg caagcttcaa
    11041 aattacacat ctgtaaatat tttttcgaaa gatatatttg aagccatagt aaattgagac
    11101 tagaatagta cactacatct gctaaaaatt tctagaaatt aatttaactt tcctaatcga
    11161 tttgtttaca tcttatttca atctactata ttatctcaat aaatgatgat ggcgactgtt
    11221 ttgtttgtgc ttgtcgattt ttgaatcctg atcgagcgga agaatatttc tgccgaggtt
    11281 gtcaagggga aaatcctgaa gatattgaat tttatgatga acaattacag gcagaaaagg
    11341 tggaggcttt gaatattcga ttggaagtaa aaaattgaat tatctacaat ctcatcaaca
    11401 ataaacctat ttcaacccca ttatctatag gcgtattttt acgccttttt atatacttga
    11461 agcacataag aaacattatg ggaagtttgc tgatggaagc actcaagaaa ttgatgttcc
    11521 ttatgatatt cctgatactt gggagtgggt gaggttttct acattggttg aaattgtcag
    11581 aggtggctct ccacgaccaa tcaaagatta tcttacttct gaagtagatg gaataaattg
    11641 gataaaaata ggtgatactg aaaagggtga aaagtatata aataatgtta aagaaaaaat
    11701 caaaaaatca gggcttaaca aaactagatt tgtaaaaaaa ggtacatttt tgttaactaa
    11761 ttctatgagt tttggtagac cttatatttt gaatgttgat ggtgcaatac acgatggatg
    11821 gttggctatt tcgaactatg aaaactcatt aaataaagat tacctattct atattctttc
    11881 atcaaatgta gtttattctc aatttctatc tctaattagt ggagctgttg tgaaaaactt
    11941 gaatagtgat aaagttgctt ctattcttat ccctctccct ccgctagctg aacaacaacg
    12001 cataatagaa gcaatcgaat cagctttaga aaaagtagat gaatatgctg aaagttataa
    12061 tagactagaa cagctagata aagaatttcc agataaacta aaaaaatcta ttcttcaata
    12121 tgctatgcaa ggaaaattag ttgaacaaga cccaaatgat gaatcagtcg aagttttact
    12181 tgaaaaaata cgagcagaaa aacaaaaact ctttgaagaa ggcaagatta aaaagaaaga
    12241 tttggacatt tctattgttt cccaaggaga tgataactct tattatggga ataaagacga
    12301 aacaacctct tatcctatat atgaaatccc agaagcatgg agatatatta aatttgctag
    12361 cctagttaac ttcagaatag gaaaaactcc tccacgcagt gaagctactt tttggggaac
    12421 tgaaatacct tgggtatcta tatcagatat gcctatatct ggttatgtaa ctaatacgag
    12481 agaatctatt tctaaattag cattaaaatc aaagaaaata gacatttcac ctaaaggaac
    12541 tttattaatg agttttaaat tatctattgg aaaagttgcc atattggata ttcctgccac
    12601 tcataatgaa gccattatat cgatattccc ctatgctaaa gaaaatatta tcagagatta
    12661 cttaatgata tttttgccac ttatctctac tttaggtgat tcaaaagatg ctatcaaagg
    12721 gaaaacatta aatagtacca gtatctccga attattaatc cctatttcta atcatgaaga
    12781 gatgaaaaga atcatttcca aagttgattt actttttcaa aaagtttctc aactttttga
    12841 gtaataagtt cctgttcctc aaaaggagct aacggaatta atagctcgct cagtgtagtt
    12901 ttaggaatat tatataaagc ttgacctgat agtttagtta ttgctttcaa ttgtttataa
    12961 aataacggag aagacaagtt aaataataga aattttgaaa taatctctga actttcgaat
    13021 ggtgttaatt ggaaaataaa tccaccagcc acaacaccat catagtcttt atcgattctt
    13081 gcaaactttc caatatgttc taaagaggtt gatacaggtg ttattagctg attatgtttt
    13141 aaataaactt gctcagagga gatgaattgt gtatcaatgt agtaatcatt atccaacaga
    13201 gaaaattcta aaggcttaat attaccacca cgtataattc taacaccttt attattaatg
    13261 cttaaatcgc ccttcttgta agaaagacct gtatttattg aaaaaatatc ttttattttt
    13321 ataacaaccc aattcatagg t
//
LOCUS       DAVKAU010000051        12847 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVKAU010000051 DAVKAU010000000
VERSION     DAVKAU010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12847
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.051"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(201..2459)
                     /locus_tag="VWX48_001681"
     CDS             complement(201..2459)
                     /locus_tag="VWX48_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9172269.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPNEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2688..2918)
                     /locus_tag="VWX48_001682"
     CDS             complement(2688..2918)
                     /locus_tag="VWX48_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU9172270.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3108..3791
                     /locus_tag="VWX48_001683"
     CDS             3108..3791
                     /locus_tag="VWX48_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9172271.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQCS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3791..4525
                     /locus_tag="VWX48_001684"
     CDS             3791..4525
                     /locus_tag="VWX48_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9172272.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVPDRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4679..5536
                     /locus_tag="VWX48_001685"
     CDS             4679..5536
                     /locus_tag="VWX48_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU9172273.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5678..6550
                     /locus_tag="VWX48_001686"
     CDS             5678..6550
                     /locus_tag="VWX48_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU9172274.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6832..7515
                     /gene="rpiA"
                     /locus_tag="VWX48_001687"
     CDS             6832..7515
                     /gene="rpiA"
                     /locus_tag="VWX48_001687"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU9172275.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7529..8740
                     /locus_tag="VWX48_001688"
     CDS             7529..8740
                     /locus_tag="VWX48_001688"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU9172276.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8742..9284
                     /locus_tag="VWX48_001689"
     CDS             8742..9284
                     /locus_tag="VWX48_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU9172277.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9300..10109
                     /locus_tag="VWX48_001690"
     CDS             9300..10109
                     /locus_tag="VWX48_001690"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9172278.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRTYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10606..11628
                     /locus_tag="VWX48_001691"
     CDS             10606..11628
                     /locus_tag="VWX48_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU9172279.1"
                     /translation="MKESENDAPKLETPLREEPRLAPQTLLEASEVLENKREESKVGI
                     TEPAQDSPILAPVEETKEEAVTEKPTNTRSLTAEDLVKISKGELHLENDLIDESFYGE
                     KALDLEGDDYQDGIKNKDGKDYLGYNSHPLLADSDGDGLADGEDDNKKEWYVTDRDSL
                     LFMELAYRDDDYIEKILDHKNLFPSLYLDRQEHKLMHNELAPFWKMKKAYYTDSGLDA
                     FLFETKSDLPYLKDGTVHMLAIRGTRVNDAKDLSADFVLLGGNKLAQADDIRKVVGEL
                     AKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDFYNHVLRKVTTFSAPKVITSRTVW
                     DAKNGF"
     gene            11638..12213
                     /locus_tag="VWX48_001692"
     CDS             11638..12213
                     /locus_tag="VWX48_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9172280.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12238..12750
                     /locus_tag="VWX48_001693"
     CDS             12238..12750
                     /locus_tag="VWX48_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU9172281.1"
                     /translation="MSAQITINHKKARYFRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLIIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         3816 a         2334 c         2910 g         3787 t
ORIGIN      
        1 cagattgaaa taagatgaga acaaatcgat tgggaaagta aaattaattt ctataaatgt
       61 tttagcaatt gtttcgtact atttcagatt cagtctacta tatatcataa tggacaaagg
      121 gcaagctgtc aagaaattac agttatttta gtaaaaaaag aagcagaaaa atttcatttt
      181 ctactccttt tctataggat ttatttttct ttttcagaac ttttaacttc agcttttttg
      241 gcagatttaa tctgaatgtt tcccttgcta gtcataactg ctttgagatc tttttcgttt
      301 ggattttcaa ggtagtagtc agtgattgtg tcctcaatat agtcttgaat agtccgacga
      361 agtgggcgtg ctcccatttt tggatcataa cctaggtcaa ccaacttttc cttgaccttg
      421 tcagttacat ccaaacgaat gttgttgcta gagaggcgct tgttaacatc tgctagcatg
      481 agctcgacaa tctgaaggag gttatccttg ctgagagcct taaattcgat aatgccatca
      541 aaacggttca taaactctgg gctaaagaag ttaccgagtt caccgaggac agaattggta
      601 cgtccttctc tagcagcacc aaatccaacg ctagcttcgg tctttcctgt acctgcattt
      661 gaggtcatga taatgatggc atccttgaag ctaacggtgc gtccttgccc gtctgtcaaa
      721 cgaccatcgt ccaagacttg aagaaacatg tgcataacat ctgggtgagc tttttccact
      781 tcatcgagaa ggatgagaga atatggattg tggcgaactt tttcagttaa ttgaccagcc
      841 tcatcatagc caacataacc tggaggagcg ccgaccaact tagccacact atgtttttcc
      901 atgtattcac tcatatcaaa gcgaatcata ctatcagcag aaccaaaaag ttcgatagcc
      961 agttgtttgg aaagttctgt cttaccgaca ccagttggcc caacgaagag gaagcttccg
     1021 attgggcggt taggggtacc aagtccgaca cgattacggc gaatagcctt ggcaatctta
     1081 tcgactgcat catcttgacc aataacatga gacttgagat cttcggctag atggatgagt
     1141 tgagattgtt ctttctcttt caaatcacca acagggatat tggttttctg ctcgataatg
     1201 tgctcaatag ttttctcgct gatgatagga gtatcctggt ctgtgatctt tttcttttgc
     1261 atttccttat acttggcaat ctggtcgcgg aagtaggccg ccttctcaaa atcttcttct
     1321 cgtgtagctt gagacttgag attttcagcc tcaatcaagc gctgatcaat tactttagga
     1381 tccacaaaat tcaaggtcaa gttcatctta gaaccagctt catctaggag gtcaatggcc
     1441 ttgtcaggca agaagcgatc ttggatgtag cgattggaaa gagttgcagc tgcttcaatc
     1501 gcagcatcgg tatattgaac gtggtggtaa tcttcgtatt tcttttgaat ccctttgaga
     1561 atagtgattg tttcgtccac cgttggttca tcgactttaa caggctgcat acgacgctcg
     1621 agggcagcat ccttttcaat gatacggtat tcattgaggg tagtagcacc gactagttgc
     1681 agttctccac gagcaagggc tggcttgagg atatttcctg cgtccatatt accatcactc
     1741 gcagaaccag caccaacaat ttcatggatt tcatcgataa agaggatgat gtcttcacgt
     1801 ttgcgaattt cttccatgag tttttgcatg cgttcttcaa attgtcctcg aatccccgtt
     1861 ccttgaacta agctaaccac atccagacgg atgacttgtt taccttggag tttatgtggc
     1921 acatcgccat cgacaatttt ctgagctaga ccttcgacaa cggccgtttt tccgacacca
     1981 ggttcaccga taaggacagg attattcttg gttctacgat tgagaatctc gatgacacgg
     2041 ataatctcat cgtcgcgccc aataacgggg tcaatgtctc cacgacgggc aatttcagtt
     2101 acattaatac caaattcttc cagcaggcct ttttcttggc taggtggcgg agtttgagca
     2161 gatccacgat tttgggaacc ataaccgccg tttccaccgt aacctccacc tgattgggtt
     2221 gggggaatag gaggagtatt gctagaaggt ctgaaattgt ttagatcatt gaagaaatca
     2281 ccaaagggat cgaagtcacg attgttcaga tccgtcatac ctttgaagag gctattgtta
     2341 ggatctgttt tgataatctt atagcagttt tgacagaggt caatttgttt ttgttttcca
     2401 ttgagattgg tgtaaagatg aattgttgag tcgttaattt tacagttttg acaaagcata
     2461 catctacctc atttctttct ttagcctgac ttgtttaaag gtcaaaaata gtcaaattct
     2521 atactctcat tataacagga ttggggtgta aagcaagtaa aaagattgaa gctttgagaa
     2581 gttgttacaa tgaaaatttt tgtgaatttg gactataaaa aaatcctatt tgtgagacaa
     2641 aaaggatttt acttagacat gcagggacaa tcccagcttg ttttagatta gtagagaagt
     2701 tcgtaaattt ccattgcgat taagtcaatg ctatcaaacg tatacgtttc gcgatcttct
     2761 acgtcacgaa gggtaaagat tgggccgttt tcttcgtcgt ggctgtacgc aacttctgca
     2821 acaacaactc cttcgcgttc aaaattacgt tttaaatttc cgccatcgtt tgccattgct
     2881 tcaaggcggt tgatgattct aaccaaatgt gattccattt tgattctcct tcatttctta
     2941 tcgttactat tttaccataa aggaggccaa cttgactaga aaaaactaag atttctcgct
     3001 aattctgcta gtttaaagat ttttaaataa attggataaa aaatttaaat tttaattcaa
     3061 aacatgttat aatcatacag tattctattt tagaaagcag tgtgactatg aatttttctt
     3121 ttttacctaa gtatttacct tattttaact atggggctgt tgtgacgatt cttatttcta
     3181 tctgtgttat ctttttggga actattttgg gtgttgtctt ggcttttggg caatgttcaa
     3241 agtttaaacc gcttgtttgg ttggccaact tgtacgtttg gattttccgt gggacaccga
     3301 tgatggttca aattatgatt gcctttgctc ttatgcatat caatgctccg actattcaga
     3361 ttggaatttt aggtgttgat ttttcgcgtc tgattccagg gattttgatt atctctatga
     3421 atagtggtgc ttatgtttcg gagactgttc gtgccggaat caatgcggtt ccaaaaggtc
     3481 agctagaggc ggcttattcg ctagggattc gtcctaaaaa tgcgatgcgt tatgtgattt
     3541 tgccacaagc agtcaaaaat atcttgccag cattggggaa cgaatttatc accattatca
     3601 aggacagctc cctcttatca gctattgggg tcatggagtt gtggaatggg gctacaacag
     3661 tttctacaac aacctatcta cctttaacac cacttttatt tgcagcattt tactacttga
     3721 ttatgacctc tattctgaca gtagccttga aagcttttga aaaacatatg ggacaaggag
     3781 ataagaaata atgacagaaa ccttgataaa aattgaaaat ttacataaat cttttggaaa
     3841 gaatgaagta ttgaagggca tcaacctcga gattaaaaga ggagaagttg tcgttatcat
     3901 cggtccttca gggagtggga aatctacctt gcttcgctct atgaatttgt tggaggaagc
     3961 aaccaagggg aaggttatct ttgagggagt cgatattacg gacaagaaga atgacctgtt
     4021 tgccatgcgt gagaagatgg gcatggtttt ccaacaattt aacctctttc ctaatatgac
     4081 tgtgattgaa aatattacct tgtcacctat caagaccaaa ggtgaaagca gggaagttgc
     4141 tgagaagaga gcccaagagc ttttggaaaa agttggtttg ccagataagg cagacgctta
     4201 tccacagagt ctgtcgggtg ggcagcaaca acggattgcc atcgcgcgtg ggttggctat
     4261 ggaaccagat gttttgctct ttgacgaacc aacttcagcc ttggatcctg aaatggtagg
     4321 tgaggtattg gctgttatgc aagaccttgc caagtcaggg atgactatgg ttatcgtaac
     4381 acatgagatg ggatttgccc gtgaggtgcc agatcgtgtt atctttatgg cagacggtgt
     4441 ggttgttgaa gatgggacac ctgagcagat ttttgaacaa acccaagaac aacggactaa
     4501 agatttcttg agtaaggttt tataatctat tttaaaattt caagacaaga ttagtgaaaa
     4561 gttcaaccag agctttttct tatagtttga aactatagga taacctagga aagaagtgtt
     4621 agagggcact agcagttttt ggtataatgg aagatatttg aaagaaaaga gaagtgatat
     4681 gacacagatt attgatggga aagctttagc ggccaaattg caggggcagt tggctgaaaa
     4741 gactgcaaaa ttaaaggaag aaacagctct agtgcctggt ttggtagtga ttttggttgg
     4801 ggataatcca gccagccaag tctacgttcg caacaaggag aggtcagctc ttgcggctgg
     4861 ttcccgtagc gaagtagtgc gagttccaga gaccattact caagaggaat tgttagacct
     4921 gattgctaaa tataatcagg atccagcttg gcatgggatt ttggtccagt tgccattacc
     4981 aaaacatatc gatgaagagg cggttttatt agccattgac ccagaaaagg atgtggatgg
     5041 tttccatccc ctaaacatgg gacgtctttg gtctggacat ccagtcatga ttccctcgac
     5101 acctgcagga attatggaaa tgtttcatga atatgggatt gacttggaag gtaaaaatgc
     5161 ggtcgtaatc ggtcgttcaa atatcgttgg aaaacctatg gctcagcttc ttttggctaa
     5221 aaatgcgaca gtaaccttgg cccactcacg aactcataat cttgccaagg tggctgctaa
     5281 agcagatatt cttgtagtcg caatcggccg cgccaagttt gtgactgctg actttgtcaa
     5341 accaggtgcg gttgtcattg acgttgggat gaaccgagat gaaaatggga agctctgtgg
     5401 agatgttgat tatgaggcag ttgcaccact tgctagccat atcacgccag tccctggagg
     5461 tgtcggtcct atgaccatta ccatgctgat ggagcaaact tatcaagcag cacttcggac
     5521 attggataga aaataagaga aacattcgat taatagagtg tattttctat agctatatct
     5581 aaaatggcag aaatgaatat taaattttag atataagatt acaaaaggag gtctgcgtct
     5641 cctttttgtt gtataataaa agtgagaggg aaaaaggatg aaagtgatta atcaaacctt
     5701 actagaaaaa gttattattg aacgttctcg ttcaagtcat aaaggagatt atggtcgtct
     5761 gctgctgctt ggtggtactt atccttatgg aggtgccatc atcatggctg ctttagcagc
     5821 tgtaaaaagc ggtgcaggat tggtgaccgt tggaacggac agggaaaata tcccggctct
     5881 gcacagccat ttacctgagc ctatggcctt ttctcttcaa gaccagcaat tgttaaaaga
     5941 gcaattggag aaggcagaag ttatcttgct ggggcctggt ttacgagacg atgcttctgg
     6001 agaaaatcta gtaaaacagg tctttgttaa tttaagccaa aatcagattt tgattgtaga
     6061 cggaggtgcc ttgaccattc ttgctaggac aagtttgtca tttccctcaa gccagcttat
     6121 cctaactcct caccaaaaag aatgggaaaa attatctgga attacgattg aaaagcaaaa
     6181 ggaagatgca acggctagtg ttctgacttc cttccctcaa ggaacaattt tggtggagaa
     6241 aggcccagct actcgtattt gggaagttgg ccaatctgat tattaccagt tacaggttgg
     6301 tggtccttat caggcgactg ggggaatggg agatactctg gctgggatga tcgcaggatt
     6361 tgtaggccaa ttccgacagg ccagtctcta cgagcgtgtg gcagtagcga cccatcttca
     6421 ttcagccata gcccaagaac tatctcaaga aaattatgtg gtcttaccga cggaaatcag
     6481 caggtatctt cccaaaataa tgaaaattat ttgtcaacaa gatagggtaa gcaaagataa
     6541 acttgtttaa aatagacaga taaatctact tccttctctt aatttatgat tcttgaaatg
     6601 cgcctgcttt aaggctaaac tagacgtatc aaagttaaga gtttgttttt gtaactggaa
     6661 agagatgaac aaatcaaata cataaaagat aaactcattt ttattcgttt ggtaaaaata
     6721 aaatgcatat ttttaaagaa agattgatga aaaatgtaga tttgatgttt ttacttgaat
     6781 aaaaagcggt ttcatagtaa aataagaact gagaatgatg gaggtaaatc ggtggaaaat
     6841 ctgaagaaaa tggcaggtat caaggctgct gagttcgtga gcgatggaat ggtcgttgga
     6901 cttggaacag gctcgactgc ctattatttt gtcgaagaaa tcggtcgtcg tatcaaggaa
     6961 gaaggattgc agattacagc tgtaacaact tctagtgtga ccactaaaca ggcagaaggc
     7021 cttaatatcc cgctcaagtc tattgaccaa gtagactttg tcgatgtgac ggttgatggc
     7081 gcggatgaag tggatagtca gtttaatgga atcaaaggcg gtggtggtgc ccttctcatg
     7141 gaaaaggtgg tcgcaacacc atcaaaagaa tacatttggg tggtggatga aagcaagctg
     7201 gtcgaaaaac taggtgcttt taaattgcca gtagaagtgg ttcagtatgg tgcagagcag
     7261 gtctttcgtc attttgaacg agctggctac aaaccaagtt tccgtgaaaa agacggccaa
     7321 cgttttgtga cggatatgca gaattttatc attgacctcg ccttggatgt cattgaaaat
     7381 ccaattgctt ttggacaaga attggaccat gtcgttggtg ttgtggagca tggtttattc
     7441 aaccaaatgg tggataaggt aatcgttgct ggacgagatg gagttcagat ttcaacttca
     7501 aaaaaaggaa aatagaaggg ggcataagat gtctaaattt aatcgtattc atttggtggt
     7561 actggattct gtaggaatcg gtgcagcacc agatgctaat aactttgtca atgcaggggt
     7621 tccagatgga gcttctgaca cactgggaca catttcaaaa acagttggtt tgaatgtccc
     7681 aaacatggct aaaataggtc ttggaaatat tcctcgtgaa actcctctta agactgtagc
     7741 agctgaaagc aatccaactg gatatgcaac aaaattagag gaagtatctc ttggtaagga
     7801 tactatgact ggacactggg aaatcatggg actcaacatt actgagcctt tcgatacttt
     7861 ctggaacgga ttcccagaag aaatcctgac aaaaatcgaa gaattctcag gacgcaaggt
     7921 tattcgtgaa gccaacaaac cttattcagg aacggctgtt atcgatgatt ttggaccacg
     7981 tcagatggaa actggagagt tgattatcta tacttcagct gaccctgttt tgcagattgc
     8041 tgcccacgaa gacattattc ctttggatga attgtaccgt atctgtgaat acgctcgttc
     8101 gattaccctt gagcgtcctg cccttcttgg tcgcatcatt gctcgccctt atgtaggtga
     8161 accaggtaac ttcactcgta cggcaaaccg tcgtgacttg gctgtatctc cattttcccc
     8221 aactgttttg gataaattga atgaggctgg tatcgatact tatgctgtgg gtaaaatcaa
     8281 cgatatcttt aacggtgctg gtatcaacca tgacatgggt cacaacaagt caaatagtca
     8341 tggaattgat acactattga agactatggg acttgctgag tttgaaaaag gattctcatt
     8401 cacaaaccta gttgactttg atgcccttta cggccatcgt cgtaatgctc acggttaccg
     8461 tgattgcttg catgagtttg atgaacgctt acctgaaatt atcgcagcta tgagagagaa
     8521 tgaccttctc ttgattactg cggaccatgg aaatgaccca acgtatgcag gaacggatca
     8581 cactcgggaa tatattccat tgttggccta tagccctgcc tttaaaggaa atggtctcat
     8641 tccagtagga cattttgcag atatttcagc gactgttgcc gataactttg gtgtggaaac
     8701 tgctatgatt ggggaaagtt tcttagataa attggtataa gatgacgcgc tatgctttgc
     8761 tggtgagagg tatcaatgtt ggtggtaaga ataaggtcgt catggcggag cttcgtcaag
     8821 aattgacaaa cttgggactg gaaaaggttg agagctacat caatagtggc aatattttct
     8881 ttacttcgat agattccaaa gcccaattgg ttgaaaagct agagactttc tttgcagtcc
     8941 attatccatt tattcagagc ttttctttac tgagtctaga ggactttgag gcggaacttg
     9001 aaaatctacc agcttggtgg agcagagact tggcacgaaa agattttctc ttttacactg
     9061 agggtttgga tgtggaccaa gtcatcgcga cagttgaaag tttagagctg aaagatgaag
     9121 tgctttattt tggaaaactt gggattttct gggggaaatt ttctgaagaa tcctattcta
     9181 agactgccta tcagaagtac ttgctgaagg tgcctttcta ccgccacatt actattcgta
     9241 atgctaaaac ctttgacaaa attggtcaaa tgctaaaaaa ataataaagg agacacacaa
     9301 tgacattttt aaacaaaatc catgaaactg ctactttcct gaaagaaaag ggaattgcag
     9361 cccctgagtt cggtctaatc cttgggtcag gacttggaga attggcagaa gaaatcgaaa
     9421 atccagttgt agtagactat gctgagattc caaactgggg ccgttcaaca gtagtcggtc
     9481 atgctggtaa attggtatat ggtgaactgg caggtcgcaa ggtcttggct cttcaaggtc
     9541 gtttccattt ctatgaaggg aatcctctgg aagtggtgac tttcccagtt cgtgtgatga
     9601 aagttcttgg atgtgaaggt gttattgtaa ccaatgcagc tggcggtatc ggatttggtc
     9661 ctggtacctt gatggctatc tcagaccata tcaacatgac ggggcaaaat ccattgatgg
     9721 gtgaaaactt ggatgacttt ggcccacgtt tcccagatat gtctaggacc tacacaccag
     9781 aataccgtgc cactgcccat gaagtagcta aaaaacttaa tatcaagctt gatgaaggtg
     9841 tctatatcgg agttactggt ccgacttatg aaacaccagc agaaattcgt tcctataaga
     9901 cactgggagc agatgcagtt ggtatgtcta cggttcctga agttatcgtg gcagcccact
     9961 ctggcttgaa agttctggga atttcatgta tcactaactt tgcggctggt ttccaagaag
    10021 aactcaatca cgaagaagtt gtagaagtga ctgaacgtgt taaaggtgat ttcaaaggct
    10081 tgcttaaagc gattcttgct gaattgtaag aaaaaagatt taaaaggggg agtgcctctg
    10141 tcttttcagg attgactgcc tatccggatt aaagaagaaa cagaggaata ctatgagctt
    10201 cttcctgctc ttataactga aagaagtgga agaataggta tgtctgatct gatagccagc
    10261 attgtgaaag acaagattct aggatactag cattagcttc ctagccaagt agactagtat
    10321 gataaggaga gatgagaatg aattgacttt ctgaatttct tagtcttatc atatatagca
    10381 caatgagatt tcgcttgagt ctgcttgtaa ataaacgaaa agaaagataa gaaataatga
    10441 aaattggtca acgaattatg cgctttggca taaaaaatta agtatcggag ttgtatctgt
    10501 tgtagtcggc tttgatttct agctccagct ggaatttcag ccaatgaagt aaagcaagat
    10561 gtaacatctg aagtggtaat aggtgtgcta gattctaagg aggaattgaa agagtcagaa
    10621 aatgatgctc caaaactaga aactcctctt agagaggagc caagactggc tcctcaaacg
    10681 cttctggaag caagtgaagt tcttgaaaac aaaagggaag agtcaaaagt agggataaca
    10741 gagccagctc aagactcacc tattcttgct cctgtagaag aaactaaaga agaagctgtg
    10801 acagaaaaac caacaaatac tcgttctcta actgcagaag atttggtgaa gatttccaaa
    10861 ggggaattgc atttagaaaa tgatttgatt gatgaatctt tctatggtga aaaagctctt
    10921 gatttggaag gggatgatta ccaggatggc atcaaaaaca aagatggtaa ggattatcta
    10981 ggatataaca gtcatccctt gctagcagac agtgatgggg atggtttggc agatggggaa
    11041 gatgataata agaaagaatg gtatgtcaca gaccgtgatt ctcttctctt tatggagtta
    11101 gcttatcgag acgatgatta tattgagaaa attttagatc ataagaatct tttccctagt
    11161 ctctatcttg accgtcaaga acacaaactc atgcacaatg aattggctcc tttctggaag
    11221 atgaaaaaag cctactatac agatagtggc ttggatgctt tcttatttga gaccaagagc
    11281 gaccttcctt atctcaaaga tggaacggtg cacatgttgg ctattcgtgg aacgcgagtt
    11341 aatgacgcca aggacttgag tgcagatttt gttttattag gtggaaataa actagctcaa
    11401 gcggatgata tccgcaaggt tgttggggaa ttagccaagg atataagtat tactaagttg
    11461 tatatgacag gtcattctct tggaggctac ctagctcaga ttgcagcggt tgaagattac
    11521 caaaaatatc ctgattttta taaccatgta ttgaggaaag tgacaacttt cagtgctcct
    11581 aaagtcatta cttccagaac tgtttgggat gctaagaatg gtttctgaga tgttggtttg
    11641 gaaagtcgta aattagctgt tagtggaaaa attaagcatt atgtggttga taatgacaat
    11701 gttgtgactc ccttgattca taataatcgt gatattgtta catttacagg taattcacgc
    11761 tttaaacacc gttctcgtgg ctattttgaa agtccaatga atgatattcc taactttaat
    11821 attggtaaac aagctacctt ggataaacat ggttatcgtg atccgaaatt ggataaagtg
    11881 cgattcttta agaaacaggc tctacctcaa tcttctagtc aaccaagcgc tgaaccaatg
    11941 gaaaatattg ccttaggaaa acaggttact caaagttcga cagctttcgg aggagatgct
    12001 agaagagctg tggatggcaa agtcgatggt aactatggtc acaattctgt cactcataca
    12061 aacttccaat ctaagccttg gtggcaagta gatttggcta aagaagaaac cattcgccaa
    12121 atcaatattt acaaccgaac agacactgcc caggatagat tggcaaactt tgatgtcatt
    12181 cttttagaca gttctggtaa agaaattgag tgaaaacgta taatatctcc taaagatgtg
    12241 tcagcacaaa ttacgattaa ccataaaaaa gcgcgctatt ttcggattga gctagaaggc
    12301 tataatgccc tcagtcttgc agaagttgaa gttttccgct ttatagctac gaatgctgaa
    12361 acggcgacac aagtttctaa gccagttcaa ccaatcagtc agactcctgt gaaagataaa
    12421 acattgataa ttcaacacag tggagcttac attgcccgct actccataac ttgggaagaa
    12481 gttccagtag ataaagatgg aaaccaagtt gttcgtagtc attcttggga aggaaacggt
    12541 cgcaaccaga ctgcaggttt tgtcctcaac ctcccaatca aagaaaatat gagaaatctg
    12601 cgagttaaga ttgagaaaaa gacgggccta ctatggaata gatggcaaac aatctatgaa
    12661 aacagaccaa ttttagctca accccaccgt aaaattaccc attggggtac gacattgaat
    12721 tccaaggtga gtgacgatga tgtcttgtaa tctgatggta gaatgacagt tagtttgtct
    12781 agtttataag aaagtactac ctgagcttga atagaactca ggtagctctc tatgaaagaa
    12841 caaaatt
//
LOCUS       DAVKAU010000052        12742 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVKAU010000052 DAVKAU010000000
VERSION     DAVKAU010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12742
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.052"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            337..1209
                     /locus_tag="VWX48_001694"
     CDS             337..1209
                     /locus_tag="VWX48_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU9172282.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(1355..1699)
                     /locus_tag="VWX48_001695"
                     /pseudo
     CDS             complement(1355..1699)
                     /locus_tag="VWX48_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1842..2153
                     /locus_tag="VWX48_001696"
     CDS             1842..2153
                     /locus_tag="VWX48_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172283.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNVSDKETAEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            2157..2873
                     /locus_tag="VWX48_001697"
     CDS             2157..2873
                     /locus_tag="VWX48_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9172284.1"
                     /translation="MKKYFIGCLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(3003..3818)
                     /locus_tag="VWX48_001698"
     CDS             complement(3003..3818)
                     /locus_tag="VWX48_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU9172285.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(3815..4720)
                     /locus_tag="VWX48_001699"
     CDS             complement(3815..4720)
                     /locus_tag="VWX48_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU9172286.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIISGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            complement(5050..5133)
                     /locus_tag="VWX48_001700"
                     /pseudo
     CDS             complement(5050..5133)
                     /locus_tag="VWX48_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            5177..7306
                     /locus_tag="VWX48_001701"
     CDS             5177..7306
                     /locus_tag="VWX48_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU9172287.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            7293..7742
                     /locus_tag="VWX48_001702"
     CDS             7293..7742
                     /locus_tag="VWX48_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU9172288.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            7801..8073
                     /locus_tag="VWX48_001703"
     CDS             7801..8073
                     /locus_tag="VWX48_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9172289.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(8427..8618)
                     /locus_tag="VWX48_001704"
     CDS             complement(8427..8618)
                     /locus_tag="VWX48_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172290.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            9046..9804
                     /locus_tag="VWX48_001705"
     CDS             9046..9804
                     /locus_tag="VWX48_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172291.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            9806..11794
                     /locus_tag="VWX48_001706"
     CDS             9806..11794
                     /locus_tag="VWX48_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9172292.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(11836..12480)
                     /locus_tag="VWX48_001707"
     CDS             complement(11836..12480)
                     /locus_tag="VWX48_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU9172293.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(12452..>12742)
                     /locus_tag="VWX48_001708"
     CDS             complement(12452..>12742)
                     /locus_tag="VWX48_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9172294.1"
                     /translation="YYAHPYASWERGTNENHNRLIHRWLPKGTKKMTPKEVAFIEKWI
                     NNYPKKCLNYKSPREDFLMANLNLKFSVRNKSRNRFKFCRSFKYPARRCSWC"
BASE COUNT         3952 a         2379 c         2628 g         3783 t
ORIGIN      
        1 tgactttcct aatagagttg ttcatatctt atttcaatct attatgtttt tcacctctaa
       61 caatcgcaat ctcttcttta tccatgaatg aaatcgcttt ctatttttgt aagtaaagca
      121 taacacgaaa tccacgaaaa tgaaaacctt tgttgtgttt tcgtaaaaaa tttgttgaca
      181 gagcacgaaa cgcctactat aattaaatca agcttaagga aataacaaaa aaacaaatcg
      241 gagggaaaga cgatgaacac attaaatgag aaagtaatca atatctgtaa agcaatagtt
      301 aaagaaactt taatccaaga catttaggag aaagaaatga agaaatcaag aaaattagcc
      361 acattaggaa tctgttcagc cttgttttta ggcttggctg cttgtcaaca acaacatgct
      421 acttctgagg ggacgaatca aaggcaaagc agttcagcga aagttccatg gaaagcttca
      481 tacaccaacc taaacaacca ggtaagtaca gaagaggtca aatctctctt atcagctcac
      541 ttggatccaa atagtgttga tgcatttttt aatctcgtta atgactataa taccattgtc
      601 ggctcaactg gcttatcagg agatttcact tcctttactc acaccgaata cgatgttgag
      661 aaaatcagtc atctctggaa tcaaaagaag ggcgatttcg ttgggaccaa ctgccgtatc
      721 aatagttatt gtcttttgaa aaattcagtc accattccaa agcttgaaaa gaatgaccaa
      781 ttgcttttcc tagataatga tgcgattgat aaaggaaagg tctttgattc acaagataag
      841 gaagagtttg atattctatt ttcgagagtt ccaactgagg caactacaga tgtcaaggtt
      901 cacgctgaaa agatggaaac attcttctca caatttcaat tcaatgaaaa agctcgaatg
      961 ctgtctgtag tcttgcacga caatttggat ggcgagtatc tgtttgtagg ccacgttggg
     1021 gtcttagtac ctgctgatga cggtttctta tttgtagaga aattgacttt cgaagagccc
     1081 taccaagcga ttaaatttgc tagtaaggaa gattgctaca agtatttggg caccaagtat
     1141 gcggattata caggcgaggg actggctaag ccttttatca tggataatga taagtgggtt
     1201 aaactttaat agtgttatga tatgacagta atcttaggat ttttatttct atttttgatg
     1261 agttggtggg ttatttcaat cgttaatagc cagaaaccac gcaaaaatga aacatttatt
     1321 ggctatatcc aaagatacga tattgatggg aatggctatc aatcattacc gtgtcctcag
     1381 aactgagagg agttcttgaa accgtaaaac cgctttgaac aagagttact tcaacccatt
     1441 ggctccgacg gagtaagttg ctttcgtgaa taccaaaatc agccgcaatt tgttcataag
     1501 ttcgatattc tcgcacatat tgaagagtgg ccataagaag gtcttctagg cttaatttag
     1561 gttttcgtcc accttttgcg tgtttaagtt gataagctgt ttttaataca gctaacatct
     1621 cttcaaaagt ggtacgctga acaccaacaa gacatttaaa tcgtgcatca gttagttgtt
     1681 tacttgcttc ataattcata gaactactat accatatttt gtttcgcagg aagtctaatg
     1741 ctaaaatctt atcagtgaga agatttctta aagtttattc tttgtagttt catctgtatt
     1801 agtacataat ttaacttaga gaaaatagga ggactaatcg aatggaatta aaagatttta
     1861 cagaaaaaga acaggaaatg attaagaaaa ggcttacaat gtctaatgtt agtgacaaag
     1921 aaactgctga gaagattctg gcgctagtac cacaagactt gattaagcga atcccgtttt
     1981 ttgtcagaaa acatgctaca acacgtacga ttaaacgcat ttcaattgaa caccctgaac
     2041 tctacgctgt agctcaaaca agtggtgaga ttccagaaaa agaacgcgaa gaattgcgtc
     2101 agattatcac aactatcttt gaacaaaaga tgaataagca tagtattaag tagagaatga
     2161 aaaaatattt tattggctgt ttgggaagca atgcctatca tagcaaggat tttcttcaag
     2221 aactagattc gcaggtctat tttctaaatc catatgaaaa gcatcttcga gatgaaacag
     2281 aattgaaatc atggtttaaa aatgagattg tagaggaaga atctatttgt ctgataggtc
     2341 attctcttgg aggagattta gctcgttatc tcgcatcgga atttgaagaa gtaaagaaac
     2401 tgattctttt ggatggtggc tatctagatt tagataagat tttacctttg gatacagagt
     2461 tagaggaaac taaaaattat atcaaatctc aaattatttc ggacttagat gttcttactt
     2521 ctaaagaaaa atctgaagca aagcattggt cagaaaatat ggagaaagct gtaagacagt
     2581 cttatcactg gaatgttgag tataatagat atgagttggc tataaattat gaaaatatag
     2641 aagcgatact ccgcctacgg agaaaaatac aagcttttaa gagagaagtg ggagatacct
     2701 tgtttattag tcctcgctat cctaatgaag ctacatggag agaggaagcc ctaaaagaat
     2761 tgccagacta ttttgatact atttttttag aaaactttgg ccatgagctt tatactcaag
     2821 cacctaaaga aatcgctagt ctaatgaatg agtggctcgc ttattttcta tgagctactt
     2881 gtattgctgg aaatggtata agatgaaaat ctacaagtca ctaattttca tataacaaaa
     2941 aaacgaacag gctctttttc tgttattcag aagagaactt gttcgttttt atcttgattt
     3001 tcttaaaaag ctctatatac atagggattt tctggtttat cgactttggt aaagctgtcg
     3061 atttccaagg ttggaaggtt ttgtttgagt tctttatggt agtgattgac cagttttcct
     3121 ttggctgtaa tccaggtgtt gttttcatac tgccgggtat tgcccttggt cagcaatcca
     3181 tagacaccag aatctgcgat acagtggata atgccgaatc ggaacagaaa ttgactattg
     3241 gcatgactgg ggtcgttata gacaaagcct gtaaactgga ttgtcttgcc ctcaaattca
     3301 tctggatagt cgtagatagc ctccatgact tccatatagt tttcattagt gatctgaata
     3361 ctatcttggg ataagtattt atccgccgcc gttcgcattt ccttttcata ggctgatttt
     3421 gaaaaataag aactagtatc tggtttcaaa tattggcttg tagtcccttc acttgtctga
     3481 atagctagat ccgttccttc cgataggggg aaatgataac ctttagcaga aacggtctga
     3541 gaatccaagc taacagttgg gaaagttaag ccgatgacaa gtggaatagc cagaagagaa
     3601 atactcgtca tcttggccaa tcggctgttc agatgactgt gggttttgac ttgcttcatc
     3661 cagatataca attgaacaat tgccaagata aaggaaagca ccatggagat ataggccaga
     3721 taggaatagt gcatgttgat gtactggttt agtttgcccg acagatggag gtaaatagtc
     3781 agttcaaaat agccagctaa aactaaaaat cgaatcatag gatgactcca atcaagagag
     3841 aatagactaa gacgacaaga gttacaattg ttatgaagtg actgataaat cgtgctttca
     3901 agtaattttt catcatgaga atatttttga tatccagcat tggaccaatg acgagaaagg
     3961 ccagaactgg tgccaaaccg aaactcgaga gaagagaagc acctataaag gcatccgcct
     4021 cactacagag cgaaagaaga aaggctaaaa tcatcaagag caggatggca aaaagagggg
     4081 tcgcactgat agaggtcaga atccgagtcg gaacgtagac ctgtattata gaagcaaaga
     4141 ggcagccaaa taccaaataa cgccccgtat caaaaaattc atcaatggcc tgcacaaaga
     4201 cttgaaaaac tttttttgca gaactcaagt aagaaaaatc atgctcatga caagccagac
     4261 gattttcttt ctgaatcggt tcttgccaga aaaatcctag aaaaattcct agtattacag
     4321 ccacaagaat ggaacccaga gctcgtaata gggcgacatg gaaggagttg ccaaaggcag
     4381 aataggtcgc aaaaagaaca atgggattga taacaggtgc tgtcacaaga aaaggaacgg
     4441 ccgtgtaact tggaaccttt ttttccagaa aacgattgat gatggggacg attccacatt
     4501 cacaagaagg gaaaaacata ccgacgaagg tcccaaaaaa gattctcccc caacgatttc
     4561 gagggagaaa atgataaacc ttgtcaggtg tgatataaac ttcaatcagc cctgagataa
     4621 tgcttcctat cagaacgaag ggaagggctt caatgataat ggagagaaaa atggctccag
     4681 tttgaagtac actagatggg agttgttgaa aagcagtcat ctagtttttc ttttctgctt
     4741 tgactttttt ctctttgtca tcagggaaag taacttgttt caaatcaggg agtttagcaa
     4801 actcttcaaa catcttgtcc aagtcgtctc gttttgtaaa ttttacagcc ataggtgtac
     4861 ctcgattcta aattctacct ctattatact attattttgc ggaaaaggga gttttttaat
     4921 ttgttttcga tagttgatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcgccttac
     4981 cgtagtacgg ttactgactt cgtcagtctt atccacaacc tcaaaacagt attttgagct
     5041 gacttcgtca gtcttatcca caacctcaaa acagtatttt gagcagccta cggctagctt
     5101 cctagtttgc tttttgattt ttattgagta tgaaaaggat tggagaaagc cttccagctt
     5161 gtggtataat agatttatgg ataaaaaata tgaaaaaatc tctcaggatt tgggagtgac
     5221 gttaaagcaa attgataccg ttctaagttt gacagctgaa ggggcgacta ttccctttat
     5281 cgcgcgttat cgcaaggaca tgactggtag tctggatgag gtggcgatta aggctattat
     5341 tgatttggat aaaagtctga caaatctcaa tgaccgtaag gaagctgtct tagctaagat
     5401 tcaagaacaa ggtaagttga ccaaggaatt ggaagaagct atcttagttg ccgaaaaatt
     5461 agcagacgtt gaagaactct atcttcctta taaggaaaag cgtcgtacca aggcaaccat
     5521 tgcccgtgaa gctggactct ttcctcttgc tcgcttgatt ttgcagaata tagttgactt
     5581 agagaaagaa gctgaaaagt tcgtctgtga aggatttgcg actggcaagg aagccttgac
     5641 cggtgcagtt gatattttgg tcgaagcctt atcggaagat gtgaccttgc gttctatgac
     5701 ttatcaggaa gtgctgagac actctaaact tacttctcaa gccaaggatg aaagtcttga
     5761 tgaaaagcag gtttttcaga tttattatga tttttcagag acagttggaa ctatgcaagg
     5821 ctatcgtacc ttggctctca atcgtgggga gaaacttggt gtcttgaaga tcggttttga
     5881 acatgcgacg gaccgtattc ttgccttctt tgctactcgt ttcaaggtga aaaatgctta
     5941 tattgatgaa gttgttcagc aatccgttaa gaaaaaggtc ttgcctgcta tcgagcgtcg
     6001 tattcggaca gaattaactg agaaagctga agaaggagct atccaacttt tttctgacaa
     6061 tctgcgcaat ctcctcttgg ttgctccact gaaagggcgc gtggttcttg gatttgaccc
     6121 agcctttcgt acaggtgcca agttagctgt cgtggatgca acaggaaaaa tgctgacaac
     6181 tcaggttatt tatcctgtta aaccagcatc agctcgtcaa atcgaagaag ccaagaaaga
     6241 tttagcagat ttaattggtc aatacggtgt agagattatt gccattggaa atggaacggc
     6301 cagtcgtgaa agtgaagctt ttgtagcgga agttctgaaa gatttccctg aagtcagcta
     6361 tgttatcgtt aatgaaagtg gtgcttctgt ctattctgcc agcgaacttg ctcgtcagga
     6421 gtttccagac ttgaccgttg aaaaacgctc tgccatttct atcgcccgtc gtttgcaaga
     6481 tcctcttgcg gaattggtca aaatcgatcc taagtcaatt ggtgtcggtc aataccaaca
     6541 cgatgtcagt cagaagaaac tatctgagag tctggacttt gttgtcgata cagtggttaa
     6601 ccaagttggt gtcaatgtca atacagctag cccagctctt ctttcacacg tagctggact
     6661 caacaaaact atctctgaaa atattgtcaa ataccgcgag gaagaaggaa aaatcacttc
     6721 acgcgcccaa atcaagaaag ttcctcgtct gggagccaag gcctttgagc aggctgctgg
     6781 tttccttcgt atccctgaaa gtagcaatat ccttgataat acaggagttc acccagagaa
     6841 ttacactgca gttaaggaac tcttcaaacg tttagatatt aaagacctaa acgaagaagc
     6901 ccaaagcaaa ctcaagtccc tttcagtcaa ggaaatggct caagagctag acctcggtcc
     6961 agaaaccctt aaagatatca ttgcagatct tctcaaacca ggtcgagatt tccgtgattc
     7021 ctttgacgca cctgtgcttc gccaagatgt cctagatatc aaagacctag tggtaggtca
     7081 gaagctagaa ggtgttgtgc gtaacgttgt tgacttcggt gccttcgttg atatcgggat
     7141 tcacgaggac ggcttgattc atatttctca tatgagtcgc aagtttatca aacaccctag
     7201 tcaagtggtg tcagttggag atttggtgac cgtttgggtc aagaaaattg atactgaacg
     7261 tgaaaaagtt aatctgtcgc tcctcgctcc aaatgaaact gactgattat gtcaagcagg
     7321 tttcactaga agacttcggg agagctttta tccatcatgt ccagtggaat aggcgtctac
     7381 gttcgacagg tgggcgattt ttccccaaag atgggcatct ggattttaat cccaaggttt
     7441 atcagaaact gggtatggag gtttttagga aaattgtccg acatgaactc tgtcattatc
     7501 acctttattt ccaagggaag ggctatcaac acaaggatcg ggattttaag gaactgttga
     7561 aagcagtgga tggattaagg tttgtaccat ccttgcccaa tagtaactct aaaccactca
     7621 agctttatcg ttgtcaatcc tgccagcaaa ggtatcagcg caagcgtagg attgatacca
     7681 aacgctatcg ctgtggactt tgtcgaggta aattgcttct gataaatcag cctgaggact
     7741 gatgaaagcc gagcctcccc gtgatatact atgtctaacc tagcagaaag aggaaatatc
     7801 atgaacagta aattttataa aatgagacgc aatcgcatga tttcaggagt tctggcaggt
     7861 ctgtcagaca agtggaattt tgatgttacc ctagttcgtt tcttgtttgc catttttaca
     7921 gttgcaaact ttggacttgg cgtgattatc tatatcatcc tagcttctat catgcctacc
     7981 aaggaagaaa tcgaagcaga aatgtacgga acaggcccac gtaaacgcaa agaagcccaa
     8041 gccattgacg acaatgaagg ctggttttgg tgaggttcta cagaagattt ggaataagca
     8101 aaaagcttta aatcaatagt ctaaactgct tgatttaaag cttttttact tttatactca
     8161 ataaaaatca aagtgcaaac taggaagcca gccacaggct gtaatttagt cggcaatgtg
     8221 aagttgacat agtttgcact ttgatttttg aatagtatta ataatatttc gccagcttca
     8281 tccacaaact atagtggatt ggaactagaa taggacacct atacttctaa aaaattgtta
     8341 gaaattgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt actataaaag
     8401 cagtaattta aacgcagttt tttaatctat ttttgctgtt gagacaatac atttttggaa
     8461 aaatggtgga tgctgataac aactgataac cagcaaataa cataagcagt gccggtaaat
     8521 tctgtaccga taaagtgtgt gtgttcaact aagagctgac cgatgaatgg agagagcaga
     8581 tagagaagtc cgatgagtat atgttctttg tgtttcatta aagcgcacct tctttcctta
     8641 taggttgaac gacttgcaag tgttaaattg aatggtatgt tatctaggta accttactaa
     8701 aatgttagtt cccgcttcct ccttttcaaa gtaagccttt tcacacttat attttacaac
     8761 tttaaaaata ggaaatcaaa tcattttcta agtaattttg cttatatttc acccaatctt
     8821 acaaaaatgt aagattaaag tctcttttgt aaggttaggt tatggcaagc ggtctttttt
     8881 tgatgtaaac tagactcata aagaacaaag gagtaacatc atgaaacaaa tcttacataa
     8941 gaaaactaga aaaccaagtc acaaagaaat tgagcgcgtt cagctgggat gcactatgat
     9001 gcaagctaca tttcatttga tgggatatta agaaaggaga ttctcatgac acttttagat
     9061 gtaaaacacg ttcaaaaaat ttataaaaca cgttttcagg gcaaccaagt agaagccctc
     9121 aaggatattc actttaccgt cgaaaagggt gactacgttg ccatcatggg tgagtctggt
     9181 tctggtaaat caactcttct caatattcta gctatgctgg ataaaccaag tcgtggtcag
     9241 gtttacttga atggaactga caccgcaacc attaaaaatt cacaggcctc tagcttccgt
     9301 cgtgaaaagt tgggctttgt cttccaagac tttaacttgc tagatactct atctgtaaag
     9361 gacaatatct tgcttccgct tgtcttgtca agaagaccta ttacagagat gatgaagaaa
     9421 ttggtggtga cagctgagaa tctgggaata aaccaattac aagagaagta cccttacgag
     9481 atttctggtg gtcagaaaca gcgtgtagca gtagcccgcg ccatcatcac agaacctgaa
     9541 attctccttg cggacgaacc gacaggagct cttgactcca agtcatctgc agccttactt
     9601 gatgtctttg atgaaatcaa tgagcgcggc caaaccattc tcatggtaac ccactcaaca
     9661 gcagcagcta gcagagctaa acgtgtactc tttatcaaag acggcattct ttacaatcaa
     9721 atctaccgtg gagagaagac agaacgtcag atgttccaag aaatctctga taccttgact
     9781 gtcatggcaa gcgaggtgaa ttagtatgtt tcgattaacc aataagttag cggtatcgaa
     9841 cttgattaaa aaccgcaaac tctactatcc ttttgcgctg gctgttctct tggcagtcac
     9901 tgtcacctat ctcttttact ctctaacctt caatcctaag attgcggaaa tccgtggagg
     9961 aacaaccatt caggctacac ttggatttgg tatgtttgtc gtcacccttg cgtcagccat
    10021 tatcgttctc tatgccaata gttttgtcat gaagaaccgt tccaaggaac taggaattta
    10081 tggcatgttg ggcttggaga agcgtcatct tatcagtatg acctttaagg agttagtggt
    10141 atttgggatt ctaactgttg gagcgggtat cggtattgga gccttgtttg acaagttaat
    10201 tttcgctttc ctgctcaaac taatgaaatt gaaggttgag ctggttgcta ccttccagac
    10261 gaaagttgtc attacagtgc ttgttgtctt cggtttgatt ttcctaggcc tcatgttcct
    10321 gaatgccctt cgaatcgccc gtatgaatgc cctccagctc tctcgtgaga aagctagtgg
    10381 agagaaaaaa ggtcgcttcc ttcctctcca aaccattctt ggttccataa gtttaggaat
    10441 tggctattat cttgccctta cggtaaaaga tcctcttaca gccttaacaa ccttcttcat
    10501 agctgtttta ctggttatct ttgggactta tctcttgttt aatgcaggga ttaccgtttt
    10561 cctccaaatc ttaaagaaaa ataagaaata ctattaccaa ccaaataacc tcatatctgt
    10621 ttctaacttg attttccgta tgaagaaaaa tgcagttgga ctagccacca tcgctatctt
    10681 gtcaacaatg gttttggtaa ccatgtcagc agcgacaagc attttcaatt cctcagaaag
    10741 ctttaaaaaa gttctaaatc ctcatgattt tggggtttca gggcaaaatg ttgaaaaaga
    10801 agacttggac aaactcttga gccagtttgc aagtgacaaa ggttataaga ttaaagaaaa
    10861 agaagtattt cgttacactt actttgctgt tgcgaatcaa gaaggaacca agttaactat
    10921 ttttgaaaaa ggacaaaacc gtgtccaacc aaaaacagtt ttcatggtat ttgaccaaaa
    10981 agattatgaa aatatgactg gtcaaaaact gtctctatca ggaaatgagg tcggactctt
    11041 tgcaaagaat gagggagtta aagaacagaa agctctaact ctaaatgatc atcaattttc
    11101 tgtaaaagaa gaatttacta aagattttat tgtcaaccat gttccaaatc agtttaatat
    11161 tttgactgct gattacaatt accttgttgt acctgattta caagcctttt tggatcaatt
    11221 cccagattcg gctatctata atcagtttta cggtggtatg aatgtaaatg ccagtgaagc
    11281 agaacaactc aaggtcgctg aggagtatga aaaatactta caaaagttta atgctcaatt
    11341 aaacactgaa ggtaactatg tgtatggtag cactctagca gatgctagtt ctcagatgag
    11401 tgccctcttt ggtggtgtct tctttatcgg tattttccta tccattatct ttatggtcgg
    11461 aactgttctg gtcatctact acaaacaaat ttctgaaggc tacgaagacc gtgaacgctt
    11521 tattatcttg cagaaagtcg gtttggacca aaagcaaatc aagcaaacca tcaacaaaca
    11581 ggttttaact gttttcttcc ttcctttgct ctttgccttc atacatctcg cctttgccta
    11641 ccatatgctt agcctgattt taaaagtgat tggtgtactg gatacgacta tgatgttgat
    11701 tgtgaccttg tctatctgcg ctatcttcct catcgcctat gtgctgattt tcatgattac
    11761 ttcaagaagt tatcgcaaga ttgtgcaaat gtaaaaaaga tacctcgact tcaaaatcga
    11821 ggtatttctt gtattctaaa tgctgaaaag ttgttcgagc aggaaggtaa ctcccatggt
    11881 caagagacca atagcaaggt tccgaatcat agctgttcta gtcggatcct ttccaagtct
    11941 ggcactagtg taaccagtga gaagaagggc cacaccgaca ataaggacag tagcagggat
    12001 gcgatattca cttgggaata tggtcactga cagcattgga ggcaaacttc taaggaaaaa
    12061 ggcaacgaag ctagaaatgg cagcgtgcca aggattggta aattcttcat actcaatccc
    12121 atatttttcc tctaccagag ccttgagtgg atttttaaga aagatcttat tggtcaagag
    12181 ttgggcagaa gttttgcatt ctccattttg gatataagca gcatagaggg attttttggc
    12241 tagttcccta tcttggtcta acaagagttt ttctcgcgaa acggcagctt cctcggtatc
    12301 ttttggagtt gaaacggata catattctcc accagccatt gaaaaggcac cagctaagat
    12361 agccgcaaat cctgataaaa agataatcca gatattggtc gtggcactgg caaccccgat
    12421 aaccacacca gcaatggaaa taattccatc gttagcacca agaacacctg cgcgcaggat
    12481 atttaaacga cctgcaaaat ttgaatcgat ttcgtgattt gtttctgacg ctaaatttca
    12541 agttcaagtt agccatcaag aagtcttctc tgggtgactt gtagttcaag cattttttag
    12601 gatagttgtt aatccacttt tcgatgaatg cgacttcttt gggagtcatt ttcttggttc
    12661 ccttaggtaa ccatctatga atgagcctgt tgtgattctc attagttccc ctttcccaag
    12721 aggcataggg gtgcgcataa ta
//
LOCUS       DAVKAU010000053        12405 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVKAU010000053 DAVKAU010000000
VERSION     DAVKAU010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12405
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.053"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            119..283
                     /locus_tag="VWX48_001709"
     CDS             119..283
                     /locus_tag="VWX48_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9172295.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPAIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            367..933
                     /gene="amaP"
                     /locus_tag="VWX48_001710"
     CDS             367..933
                     /gene="amaP"
                     /locus_tag="VWX48_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU9172296.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            945..1115
                     /locus_tag="VWX48_001711"
     CDS             945..1115
                     /locus_tag="VWX48_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU9172297.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1154..1762
                     /locus_tag="VWX48_001712"
     CDS             1154..1762
                     /locus_tag="VWX48_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9172298.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1793..1996
                     /locus_tag="VWX48_001713"
     CDS             1793..1996
                     /locus_tag="VWX48_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9172299.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2106..2378)
                     /locus_tag="VWX48_001714"
                     /pseudo
     CDS             complement(2106..2378)
                     /locus_tag="VWX48_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3147..3917)
                     /locus_tag="VWX48_001715"
     CDS             complement(3147..3917)
                     /locus_tag="VWX48_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU9172300.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSNIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3932..4780)
                     /locus_tag="VWX48_001716"
     CDS             complement(3932..4780)
                     /locus_tag="VWX48_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU9172301.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4777..6252)
                     /locus_tag="VWX48_001717"
     CDS             complement(4777..6252)
                     /locus_tag="VWX48_001717"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU9172302.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLERQIPSIYALRGKLKEDDQRRMVAAYLGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6575..7930)
                     /locus_tag="VWX48_001718"
     CDS             complement(6575..7930)
                     /locus_tag="VWX48_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9172303.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7940..8257)
                     /locus_tag="VWX48_001719"
     CDS             complement(7940..8257)
                     /locus_tag="VWX48_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9172304.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8274..8591)
                     /locus_tag="VWX48_001720"
     CDS             complement(8274..8591)
                     /locus_tag="VWX48_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9172305.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8606..9502)
                     /locus_tag="VWX48_001721"
     CDS             complement(8606..9502)
                     /locus_tag="VWX48_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU9172306.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9505..10767)
                     /locus_tag="VWX48_001722"
     CDS             complement(9505..10767)
                     /locus_tag="VWX48_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9172307.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11047..12225
                     /locus_tag="VWX48_001723"
     CDS             11047..12225
                     /locus_tag="VWX48_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9172308.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLISQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEKCSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
BASE COUNT         4305 a         2461 c         1901 g         3738 t
ORIGIN      
        1 caaagaaatt gattttttga tattaaaata aaaaaggagg gtaggcagtg ttgtgatcaa
       61 ttattgctgg aggtcttatt ggtctcttgg caggtaaaat cactaaaaaa gtagttctat
      121 gggaatcatc gcaaatgtat tcgctggttt agtcggggca tatgcaggac aatctctttt
      181 aggtagttgg ggtccagcaa tcgctggaat ggctttgctc ccatctattg taggtgcagc
      241 gattgtgatt actgtagtgt cattctttac aggtagaaag taaacttttc gccagtaaag
      301 ttagcaaact atttttaaat caatgacggg aaaaatagtt taaatgttaa atcgaaagga
      361 ttgtatatgt caaaagcaaa gaaaatatgt ttcattattt tctgtatttt aatcttgaca
      421 attttccttc ctgttttgat agattatcat caagttagtg atctaggtat tcatctactt
      481 agctggagac agaactccgt agttgaattc tatcttgcta gatatgtctt ttgggggaca
      541 gtggttctat caactttagt tttattatcc attttagttg tgatgtttta tcctaaacgt
      601 tacttggaaa tccaacttga aactaaaaac gatacattaa aattaaagaa ttcggcaatc
      661 gaaggttttg ttagaagttt ggtgagtgat catagattga tcaagaaccc aactgttcat
      721 gtaaatttac gaaaaaataa atgtttcgtt catgtagaag gtaaaattct tccttcagac
      781 aacatcgctg acagatgcca aataattcaa aatgaaataa ctaatggatt gaagcagttt
      841 tttggtattg agcgtcaagt aaaacttgaa gttgcagtaa aaaattacca accaaaacct
      901 caaaacaaaa agactgttag tcgtgtgaag taaggaagta aaaaatggaa tggcttaaac
      961 aatatcgata tccaattatc gctggtctca taggcgtatt tctggcttgt ttgattgtct
     1021 cctttggctt cttcaaaaca atatttgtat tgattttagg agcactggga gttgcagctg
     1081 gattatatat cgaaaaaaac tatatagata aataaaaaaa taaaaattac taatttaatt
     1141 aaaggagttt catatgtcaa acgaaaaaaa cacaaacact aacgtagaaa agaaagatgc
     1201 tactgttgta gctcacgaaa tcaaagggga acttacttac gaagataaag ttatccaaaa
     1261 aatcattggt ctttcactag aaaacgtttc aggtcttttg ggaatcgatg gtggtttctt
     1321 ctcaaatctt aaagaaaaaa tcgttaacag cgatgacgta acaagtggtg ttaacgtaga
     1381 agttggtaaa acacaagttg cagttgactt aaacgttatt gttgagtacc aaaaaaatgt
     1441 tccagcttta tattcagaaa tcagagaaat cgtatcttca gaagttgcta aaatgactga
     1501 cttggaaatt gttgaaatca acgtaaacgt tgtcgacatc aaaactaaag aacagcatga
     1561 agcagactca gtaagccttc aagatcgcgt atctgacgtt gctgaatcaa caggagaatt
     1621 cacttcagaa caattcgaaa aagctaaatc tggtcttgga tctggtttct caactgttca
     1681 agaaaaagtt agcgaaggtg tagaagctgt taaaggtgca gcaaatggtg tagtatctca
     1741 cgaaaacact cgtgtaaact aagataaaat aaatataaca ggagaaatta tcatgtcagt
     1801 agaagaaaaa ttaaatcaag ctaaaggttc tattaaagaa ggtgttggaa aagccatcgg
     1861 tgatgaaaaa atggaaaaag aaggagcggc tgaaaaagtt gtttctaaag ttaaagaagt
     1921 tgccgaagac gctaaagacg ctgtagaagg tgctgtagaa ggtgttaaaa acatgttgag
     1981 tggcgacgat aaataaggtt aaaagttact ttatcttttt ggtaacatta gtcaaaagag
     2041 tctgagtcga gatgattctc agaaaacaaa aagctagaga ttcccaattg cggaactcta
     2101 gctttttaat tttgcctctt tctcttatta tatttcagca ggttgttggc catgagtatg
     2161 aatcccatgt caattctcac ttgacgcttc cctctcagat gacatctctt ataacccaaa
     2221 caaaccttta tctgcccaaa gacagatttc atatcaatct tacgtttagc gaaaatttgt
     2281 ctacccttgg aagataaaag tgcctgatat tctttagttt ttaaacactg gtaacgttca
     2341 ttcatataca gtctcttttg aggggctgat tcaggttcat aatcgcagtc aacattgatt
     2401 tcaaggctgt ttgctttcta tctccccttt ttcatgatat attttcgtac aggtgcttca
     2461 atagtttcta tagtaaaatg aaccaaaaat agtacacgtt gcggtataat gttcttatgg
     2521 catattcatt agattttcgt aaaaagttct ctcctatttg tgagcgaaca ggtatagtca
     2581 attgattgtc agtttgaaga ccaagagtcg taaggcaaag gatatggcag aatccatcca
     2641 agggtggctg gcacaatttc tagtgaacct ctttaaatct attacgtttg actgtggaaa
     2701 agagttttca aaatggaaag atatttccaa tcatcacgac agtgagagct tttttgcgaa
     2761 tctaggatgt ccaagacagc ggtgtctcaa cgaacattca aatagacttt taaggtgtca
     2821 tgacttgcca aagtagacag atttcaacga agtcagtcaa gaattttagg ctggacaaaa
     2881 actcaatttc aggagaaaat gaaataaata ttcccacaat aaaacgcata gtatcaaagt
     2941 ttttccaata cctgatatta tgcatttttt aattttaaag actttttccc agcctcaaga
     3001 aatcacatcc cacctaaatc ctttggatac caaatacctc atcaggtatt ttctgagttg
     3061 gtaagactgt ctagcttaat ttgacaaatg gagggcgtta aatccagttt ttacaggaag
     3121 tctatttaaa tattttcaca ctgaccttac aaaatatgaa ataaattata taaagtcatt
     3181 cccatgacaa agaataacat ccctttaaaa cagtatctta cccaattttc aggtaagact
     3241 tttgatacaa ccgtccccaa tacccctccg catatagaag caagaaaaat aactggaaca
     3301 ggtgctaaat gatactgatt taaacctgta accacaacaa ttgtagccaa atgagataac
     3361 tgggaaaaga aaataattgc aagagaatac atcgttgctt cttttatcga aatagaaaaa
     3421 aacaccatca ataaagatac attgagcgga ccaccaccaa tccctaaaaa actagaaatt
     3481 aagcccaata gaagaccaca aatcatatag aatcctatct tatcaaattg ataagttttt
     3541 ttaaaatctg ttaaaacaaa tgatacaagt agcatcacaa atagtaaaat catttgaaca
     3601 atggatacta gccgtactga taactgagat aacaaaactt gaaaaataag atgacctaga
     3661 aatcctccta aaacagaaga aaaggatacc gtaaaaatca atctccattt tatctcttta
     3721 ctttgtgaaa atcttttgat tgttgaaata atcgccatta taaaaacaga gaaactagaa
     3781 taaaaagcaa tattactgac cgaatggtat ccaaaactat ccataagtgg cttaattata
     3841 attccaccac ccatgcctga tatagaaccc aatccactag ctattataat gattagaaaa
     3901 taaataatct caaccacttt ttaagtccat cctattcttt caaacatcta aaacctagat
     3961 ggctactagt ggaagtagaa atacatccat ttctagcagc tactcggtat cgattacaat
     4021 aagaacaatg acataaaaag gaacctcctc tgatagcata ctcctcatct tgtatcccat
     4081 attttggtaa ctcatagtca tcttcattaa aactagctaa taaggtatat ctcggattgc
     4141 gacaccattc ccaaacattc ccaatcattt gatatagacc aaaatcatta ggtaaaaatt
     4201 catagacagg agccgttcct ataaatccat ctaaggcagt attttcataa ggaaatcttc
     4261 cttgccaagt attggcatga taatatccac cttctaaaag agtatctccc caaggatatt
     4321 cagattgtct tcctcctcta gcagcatatt cccactgtgc ttcagtcggt aaagacattc
     4381 cgctccaatt acagaaagcc aatgcatctt ctaaagcaac atgaactact ggatggtctt
     4441 ctaaacccac tagattacta ttctcaccgt agggatgttt ccagcaagcg ttcggaactt
     4501 gtaaccacca cggagcccca gcaggatgag gatatccctc cctttctgcc tctggaacga
     4561 acaatataaa aacaaaagac cactcttgtc gctcagctag tgttttatag cctgtttctt
     4621 tcacaaattg agcaaattct tgattcgtaa ctggagtatc cgcaatggaa aaatccttta
     4681 cactaacagc gacttgagga ccttcaaaat catctaaaaa gccctcttca gaatttgttc
     4741 ccatcataaa tgtcccaccc ttgatttttt tcattttcat gattgactat cccccgtttt
     4801 cgttagagtt ggcgttattt tagaaagttc aacaggaact aactcttcat ccacaacaaa
     4861 accttcttct ctatatctaa gaaagtctac taattttttc ttcatctgac gaacaatagg
     4921 ttgatatttt tcacttggat acaaatcatt catttcatgc ggatcttttt tcatatcaaa
     4981 taactgataa tgatttaaaa caggaaacca gataaatttc cactggtctg tcaagatata
     5041 ttgactagaa tcttttccta aagcatgttc accatgaaat tctgttcgcc acccctcgta
     5101 ctgtccaaat aataaattct taacactccg tccatctagt tcatctgtag tagttcctcc
     5161 tgccaaatcc acgagtgaag gaaaaatatc ttgaattttc actaattgct tgattgttcc
     5221 cctattacca gctatcaatc cagccggatc gtaaatgaac gaaggaatgt ggatacttcc
     5281 ttgataagga tatccctttc taaacagata atgttcacca agctgatctc catgatccga
     5341 aacaaaccag ataatcgtat ctttatcatg acgaaattct tttagggcag tcaaaaagcg
     5401 actaatttga tggtctatat gagtaatcaa tcccaaataa gcagcaacca ttcttctttg
     5461 atcatcttcc tttaatttcc ctcttaaagc ataaatagac ggaatttgcc tttctaatac
     5521 ttcccaattc ccgatatgca aatcgagaaa ttgaggcaag cgttccatat acatatcaaa
     5581 atagtatttt gggggattta atggagcatg tggtttttca aaagacattt tgagaaaaaa
     5641 aggaaccgtt ggatctcttc tttgtaaaaa tgaaatggac tcactcacaa cccagtttgt
     5701 tggatgtaac ttctcatctt tatcccaagg tctagcttcc caagaattac aatccattcc
     5761 gtcatcaatc aaatcaacat cataaccaac tttacccttt aaaaaggcta gatagtcact
     5821 agcataatca aattgacttc cataagcctt atcatacttt ctatcaacat gtagataccc
     5881 atcgtgaagt aagacatgat caaacccaag tctctgtctg gaaggaaaaa catgcatctt
     5941 accaatacac tctgtttgat aacccatatc tttaaagact tttggaagag tattagtaaa
     6001 attccaaggc acctcatctt gataaccaac acgtccactt ttatcttggt ctaaaccagt
     6061 caataaagct gccctagcag gaacgcaaga aggaactgga gaataggcat tttcaaaatt
     6121 ataacctaca ctagccatca tatctaatgt tggagtgcta actagcttat ccttactatt
     6181 caaggataag gcgtctgctc tcatttgatc tacaacaatc aaaataatat ttggctgttt
     6241 tgtctgaacc ataaaatctc ctttctaata tggcaaaaga ggcacaagaa gatatctacc
     6301 tttactgcac ccctttctat atcaatctct ctatataaaa caataacatt cttgttatgt
     6361 tttatataaa aatgaactaa aatatgacta aatcgattag gaaattcaaa tcattttcta
     6421 gtactgtttt agaagttaca gtgtactatt ccaacttcaa taaactataa acctttgtct
     6481 attaacaatt ttagtggaga taagaaatcc tacacctaac tcatcttaca cgtaatctat
     6541 ttctatttta tcacaaaaaa cgcaagtaag accattaact caattcagtt ttatctgcca
     6601 ttttcacaaa tgggaaataa gtcaagacac taataatcaa acaaacaact gataagatga
     6661 tggcacgcca atcaaatgct gtagagaaga aaccatataa aattggaggc attacccaag
     6721 taacattttg tgtaacaggt gaaacaagac cccagcttgt tgcccagtaa gctaccgttg
     6781 ccatgaaaac cgggctaagt acaaatggta taaatagcaa aggattcaag acaactggta
     6841 aaccataatt gaccggctca ccaatattaa acagaactgg tgctagacca agtttagcaa
     6901 cttttcgata atgactgttt cttgaaaaaa ttaaaatagc aagtactaat cctaatcctc
     6961 caaaccagac aaacgcccca aaagacccac ttgtccatat ataaggaatc ggttcacctt
     7021 tttggaaagc atccagattc gctaacatag caactccaaa tagcccttcc atgatgggag
     7081 ccaatacatt tcctccatgg agaccaaaaa accagaataa cttattcaaa aagatcatca
     7141 gaataactgc aaagaaactt tgagacaaac ctagtaatgg cgtttgtaac accttgtaaa
     7201 cccaatcaat caataagtca ttgctaagta aatggaaaac ataagtcaag atggctacta
     7261 tatacatcgc cataaatcct ggaatgatag aagtgaacgg cttagcaatc gcagggggaa
     7321 ctgaatctgg taacttgatt acccagttct ttttcattac tttacagaaa ataatagagg
     7381 ctaaaaatcc aatcatcatg gctgtaaagt atcctctggc attaatatgg tttcctggaa
     7441 tcacattccc aatagttacc atcagatttt taccatcaaa tgctagatta tcaattcctt
     7501 gtaagatttg atctaatttc acatctccta catttgccaa agggaaactc tttgtaactg
     7561 tacttccaat cgaaatgaca aacgaagcaa gtgataccaa accagcagaa actgtatcaa
     7621 ccttgtaaat cttagcgata ttcactccca agcaatagat gaacaacaag gaaacaattg
     7681 gtatacttcc cttgaatacc aaattattga tgtcaacaag ccactgaaag gttttcgtaa
     7741 tactttctag gtgaaattgt tgtggtaaat ccactagaaa agcatttaat aacaaagcaa
     7801 tggaacctgt cataataaca ggcatagtcc ccacaaatga atcacgtaaa gcaactaaaa
     7861 acttctgatt cccaactttc attgcaattg gagagagttt ttcttgcatt ttatccaaca
     7921 ttgtattcat actaaactcc taattttttt caaatcgttc gtatacttct accacttctt
     7981 tcgccaagtc aacaaaagtc agactcgtca ttaaatgatc ttgcgcgtgt accatcaaga
     8041 ggctaattga tgtttcttcc ccctgtgcct ctcttgtcaa catttctgtt tgagccttat
     8101 gcgcctgtaa taaggcagca ttcgcatcag ctaatcttcg attggcttta gagaaatccc
     8161 ctttttttgc tgcctgaata gcctccatag cattactttt ggcttcccca ccatacataa
     8221 ttagccccat tgcagattct aaattacttt cattcatagc attctcctca atcttagtct
     8281 aataaacttt cagctaaatc taagacttta gaaccattca tcattccata atctgtcatc
     8341 ggaataaccg ccacaggaat ctgtctatct tttagttttt cttgaaagtc ccctagtaaa
     8401 tagcgaactt gagggcctaa aagcaacaca tttacttcct ttgttgctac aatttcttct
     8461 gcttcaggag ctggaactgc aaaaatttct gcatccaacc ccttatcttc tgctgccttt
     8521 tgcatctttg tcactagcag acttgtactc atacctgctg cacatgctaa cataattgtt
     8581 actttagcca tagcttactc ctttatcacc tatttactga cctagccaag cgagatactg
     8641 tatgtctcac tcctctaatt gccttgctca atgcataaat attatcgact gttgccagtc
     8701 ccccatatcc tgcgtcacct atatgttgaa tatcaactcc acaaatttta tttctaagtg
     8761 caatttcctt aatagtatct gtatcagatg tttcttggct agtaccaata gcactcaata
     8821 caagaccacc cttactatga acgagatcaa cgacttcacg caactcttgg tcatgaaagg
     8881 ctggaacggt tccaactgct ggaacaagta tcacatccgc acctgcttcc aacaattgct
     8941 ctgcgacaga aagctctgcc acaggctcat tcactcctgc cccgtgcatc ttacctgcaa
     9001 taatcaaacc agaaaagttt tccttagcag tttgaacagc cttaatgatt tctcgattgc
     9061 taactcctgt tccaggattt ccagtcaaac agacaaagtc aaaacctaac tcctctattc
     9121 gcttcaatgt ttcaacacta gcaacacgac ctgcaacaat ttcctgtgtt tcctctagca
     9181 tctttgcaga tgggtcaatc ggttccaaat ttacaccaat tggacaagca acaagctggt
     9241 gtaagcgatg aataacatca tcacctgaac tatccaaagc ataaatttta ggctcaaaaa
     9301 catcaacaca attcaataaa atcatatcag ctccaaaagc tctagcaatt tcagaattag
     9361 ttatatcccc aacaaatgtc tcacgagtaa ctacattttc agatagaaca actctacctt
     9421 cacttgctaa aatactttgt tttaattctt cagcattcat ctgtaatatc tcagatggat
     9481 ttgcactaat taaacgtttc attctcaatc ctccaataac ttaaaccgtt tttcaatagc
     9541 tattacaaat ggtaaataaa gtaagacatc caaaacaatc aatacaattt gtaataatga
     9601 accagaaata cttcctgtag caagtaaacc acttataaca ggtggcatag tccaacctgg
     9661 atctgtataa gttagcggaa ccaaacctga tgccattgct ccccacgcta ctagtaagtt
     9721 aaacattgga gctaagataa atggaactag taacaaaatg ttcaaaacaa taggaacgcc
     9781 aaacattgct ggttcattta tattaaataa tccaggtata acagttatag gtgccaaagt
     9841 ttttagttgt ttactagctt tcttcttatg tgctaaatat cctaacgcaa gaactaaacc
     9901 tatggttgca ccaccgccac ctatgaatac aaaattatcc ataaatacgc tagtaaaaat
     9961 atttggaaga gtttctccag tttgataagc tactttattt gcatctagat tagctaacca
    10021 taacggtttc ataactgcat taacaacatt tcctccgtgt aatcctacaa accaaaaact
    10081 actattaagg aaaattaaga taagaagacc aataacatta tttcctaaaa gtccaagtgg
    10141 acctcccaaa gctacttgag caatttcatg aagattaggt aaacttaatt tatctaaagt
    10201 tgcataaaca atcaaccaac caacaatagt cactgcacca ggaataatgg cactaaagct
    10261 tttagatact gctggtggaa caccatccgg catttttatc tgtatattat gatttataaa
    10321 ccattggtag atatagccat taatcaatcc taaaatcata gcaacaaata aaccttttga
    10381 tgccatgaaa gcggtaggca ttcctgctcc agcctctcct gtaatgaaag gcgtaactgt
    10441 aataaaagat gataatgaca caataccagc aggaatacca tcaactttgt attgtctagc
    10501 cataaagtaa gcgataccaa aactagctac aagaccaagt aatccaaaac tactatcaac
    10561 acccttccat aaatagtcag caacaccaat atcacccaga tatttttccc atcctggaat
    10621 aggaaaactt gcaataacca ttagtaatga acctatcaac aataaaggta tagttagagt
    10681 aataccgtct cgaatagaaa ccaacgcttt attattaccc aatctagccg ctactggaag
    10741 taacttttct tgtaataatt tttccataac cttttcctct taaatatatt ttattatcaa
    10801 aagttatcaa ttatctttat tttttgacgt caagttgtta tttgattatc ttttgttatt
    10861 tatattttac aactataaga aagccttgtc aaggatttgt gtaaatattt gattattttt
    10921 tattatcaat atataataaa aagagaccag taagcaatga aaagcttaaa aagattaaca
    10981 tctacattta tccatagtaa aaaatcatag gattttaaga atctgacaac taggaagaaa
    11041 actaatatga ccttatctaa gaaacaatta caactacgag ctaaaatact ggaaacagtt
    11101 tacacattag gtcccatttc acgaattgaa atcgctacta aaacaggaat aacacctgca
    11161 acaactagca gtatcacaaa tgatctgatt aaagaaaaca ttctcttaga acttggtgaa
    11221 gacgaacacg atacaagcgt cgggagaaaa aaaatcctgc tagacattca agctaaacga
    11281 ttttactaca ttggttgtga actatctgaa aaacatttca cttttgcttt aggagataat
    11341 ctaggaaata tcttaaagga agagaaagaa attgttacta aacagttaat ccaagaaaag
    11401 ggaaatcaac tcattagcca gacactaaag caattcttaa ataactgctc tgattatgaa
    11461 atagaagcaa ttggaatcgc gctacctggt cgctatttag atgattataa aataacaaca
    11521 aacaatcctt tatggcaaca tatcgactta gaaatgattc aatcccactt tgataagcct
    11581 ttgtttttct ctaacaatgt taactgtatg gctataggta aacgcctatt tagtcgccaa
    11641 cagaatgacc ctaattttgc ttattttcat tttgctagag gtatgcactg ttcttatatc
    11701 tacgacggaa acatttatgg gaaaggaaat ctaatgattg gagaaatagg gcatacagtt
    11761 gtttcatctg agggagaaaa atgtagctgc gggcgcaagg gatgcttaca aacttttgct
    11821 ggagaatctt ggttaatcaa aaaatcaaaa attctatatc atcaatctcc ctattctcta
    11881 cttcctagtt tagtcaaaaa tgccgatgat attgatatcc aagttatttt aaccgcttat
    11941 caattaggtg acactggaat aatcacactt atccatcaag ccttactcta tcttagtcaa
    12001 accattttaa atatcagtat gatgattgac tctcaaaaaa tctacctaca tagtccttta
    12061 ctaacaaatc aacacatcat ccaaaaacta tatagtgaaa tgaactacaa acccaaactg
    12121 ctctataatc gcctacctga agtcattatt gaaccttaca atgattttac agccgcacac
    12181 tcagctattg cactttgttt gtatcataca attctacatt cctaattttc tattacattt
    12241 aataaatagg ctaaaaagag ggagtatatc ataaaaagcg aacaaacctg ttttctgaaa
    12301 atcagaattc tgttttgttc gctttcttta tatttggaat tatactccta tctcccattt
    12361 ttcataatgt atagtaaaat gaaataataa caggacgaat cgatc
//
LOCUS       DAVKAU010000054        11888 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVKAU010000054 DAVKAU010000000
VERSION     DAVKAU010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11888
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.054"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            9..1001
                     /locus_tag="VWX48_001724"
     CDS             9..1001
                     /locus_tag="VWX48_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9172309.1"
                     /translation="MNGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQKVI
                     EELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNAIVE
                     YFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSGVVY
                     VSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDLKVI
                     YGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISIIGFD
                     NIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1609..1686
                     /locus_tag="VWX48_001725"
                     /pseudo
     CDS             1609..1686
                     /locus_tag="VWX48_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            1899..2054
                     /locus_tag="VWX48_001726"
     CDS             1899..2054
                     /locus_tag="VWX48_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172310.1"
                     /translation="MEKLQFFLSQRACGCWKQAEKAVKLGSSETREENIILKGVPFIA
                     QPVTGDI"
     gene            2189..3550
                     /gene="trpE"
                     /locus_tag="VWX48_001727"
     CDS             2189..3550
                     /gene="trpE"
                     /locus_tag="VWX48_001727"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU9172311.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYIVFDHKKEKIHVIEDAFYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3547..4113
                     /locus_tag="VWX48_001728"
     CDS             3547..4113
                     /locus_tag="VWX48_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU9172312.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            4124..5128
                     /gene="trpD"
                     /locus_tag="VWX48_001729"
     CDS             4124..5128
                     /gene="trpD"
                     /locus_tag="VWX48_001729"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU9172313.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5125..5892
                     /gene="trpC"
                     /locus_tag="VWX48_001730"
     CDS             5125..5892
                     /gene="trpC"
                     /locus_tag="VWX48_001730"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU9172314.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGIALMQAENVVQRIKELQIDKG"
     gene            5879..6478
                     /locus_tag="VWX48_001731"
     CDS             5879..6478
                     /locus_tag="VWX48_001731"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU9172315.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            6456..7679
                     /gene="trpB"
                     /locus_tag="VWX48_001732"
     CDS             6456..7679
                     /gene="trpB"
                     /locus_tag="VWX48_001732"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU9172316.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7672..8448
                     /locus_tag="VWX48_001733"
     CDS             7672..8448
                     /locus_tag="VWX48_001733"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU9172317.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(8420..8521)
                     /locus_tag="VWX48_001734"
                     /pseudo
     CDS             complement(8420..8521)
                     /locus_tag="VWX48_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            8750..9481
                     /locus_tag="VWX48_001735"
     CDS             8750..9481
                     /locus_tag="VWX48_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172318.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHASYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            9496..10647
                     /locus_tag="VWX48_001736"
     CDS             9496..10647
                     /locus_tag="VWX48_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU9172319.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDNYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(10699..11358)
                     /locus_tag="VWX48_001737"
     CDS             complement(10699..11358)
                     /locus_tag="VWX48_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU9172320.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            11428..11874
                     /locus_tag="VWX48_001738"
     CDS             11428..11874
                     /locus_tag="VWX48_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9172321.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQTLRKFVSLAFE
                     NEDIDNISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
BASE COUNT         3761 a         2092 c         2728 g         3307 t
ORIGIN      
        1 tgaaaaatat aaatgggaaa aaggtaacta tttatgatat tgcacgttta tcaggttttt
       61 ctccaaaaac agtttcacga gttattaatg gtggagtaaa tgttaaagaa gaaacttatc
      121 aagcgattca aaaagttata gaggaattgt cgtatattcc aaatgcgtat gcaaaaaatt
      181 taactaaaaa agaagctata aatatattga tttctgtaaa aaaaatcgac tcttttcctt
      241 taatttggtt tcatacgctg ttagataaag tgttacggac gtgtaaagaa tttggtgtta
      301 atgctatagt tgagtacttt ggagaggagg atacaattag taattcaatt atatcaagca
      361 caggtagcct agtagatggt gttattgttt tttatgaaag tgtagatgat atcagaattc
      421 agtatttaaa gaagaaccat atgccttttc ttgttttcgg tgaatctcaa acgtctggag
      481 tagtctatgt atctaataat aattttcaag ctacttatga tatgatgaaa gctgtaactg
      541 aagaaaaatt taaaaatatg tggttgctta tgggaggaga atctcatgtt aataaggatc
      601 gtgaaagagg tgtgcgttct tttctgaatg ataaaaatta ctttatggat ttaaaagtca
      661 tttatggctt atctacaatt gattcagttt attcttatgc aatgcagcac ttgactaccc
      721 aaaattatcc ggacattatt tttgtttcag gagatgaaaa ggttcagggc ttgattcgtg
      781 cgtgctatga gaaaggaatt cttattccag atgatatttc tatcattgga tttgataata
      841 ttcctatttc tcagtattat actccagctt tgtctacaat tgctcccaat tatgttaaat
      901 tggctaaaga aatgatagaa ggtgttttag caattattaa aggggaaagt gtcacatctg
      961 ttgaagtttc tcctaaattt gttaggagac agagtttcta gtattgttta attcttgaaa
     1021 atcctagtgg aaaatatgga gtgttctaaa ataagttctg tttagcctcc attcagtttc
     1081 tattgagttg gatccaattt ctaacgagtg ggacatgttc atgttcgatc taaggaagac
     1141 atggtcacat tcgaatgata ttttcaaaaa aatcgtaaaa aagtcttgac aaagaaaaaa
     1201 caaagtatta aaataagttc aacaaatcag aaaagtaact atttttgatc ttcagggagc
     1261 ctgtggtgat tgtgaatagg tggttggaag tagtgaaagt gggctgattt tgaaaatgaa
     1321 tttgaaacaa tgaaaattcg gtgcgcacac cttacagtgc agcttgttgt taaacaaggc
     1381 agagatgtaa agggatagtc cctttataat tgaggtggca ccgcgttacc aacgccctca
     1441 cacggaagta tattctgtgt gtgggctttt ttctatccgt cgtttggttt atcttttatt
     1501 agggccttaa gtcgctttga tgaacttgag ttctatctac agctccttgc ctcctactaa
     1561 aagtaaacaa aaaggctgga ctaatacgaa aaaagctagt aatactcaat gaaaatcaaa
     1621 gagcaaacta ggaaactagc cgcaggctgc tcaaaacact gttttgaggt tgtggataga
     1681 actgacgaag tcagctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     1741 aaccaatacc tacggcaagg cgacgttgac gcagtttgaa gagattttcg aagagtataa
     1801 aggtgtaccg agatgaacat ctcttcatca atgtctctgg tcgtggaggc aaggacctag
     1861 ctgcgattgc agactaccta gaagctaaaa aataatagat ggaaaaatta cagttctttc
     1921 tctcacagag agcttgtggt tgctggaaac aagcagagaa agctgtaaag ttgggttcat
     1981 ctgaaacgag agaagaaaac atcattctca agggagtgcc ctttatcgca cagcctgtta
     2041 caggagatat ctgagacagg aatgagagat aggagaaatc ctataattga ggtggcaccg
     2101 cgaatttcgt cctcacgcaa gttattttgc gtggggattt ttcatacagt cgctacgaac
     2161 tagaattaga actgaaaggg aaattacaat ggaacgaatc attcatggag atgtcttatc
     2221 accaatcttg gcttatatgc gcttaaaggg gcaacacaag gttatcttag agagtattcc
     2281 gagagacaag gaaacagctc gtttttctat cctagcctat aatcctgttt ttgagattaa
     2341 gtttgaaaat ggagttcttt atcaaaatgg tcaagtgatt gatcgggatc ccttggattt
     2401 cctttatgaa gtgattcata agagtcagca ccattcagag ctaccttttg gtggtggagc
     2461 cattggtttt gtgggttacg atatgatttc gctttatgaa gaaattggtc aaatccctga
     2521 ggatacaatt gggacgccag acatgcattt ctttgtctat gagagctata tagtctttga
     2581 ccacaagaag gagaagatac atgtcataga ggatgcattt tatagtgagc gcagtcaaga
     2641 ggccttggaa aaatccttga accaagtgct tgaggaatta cgcattcctg ctccaaatga
     2701 atttgaagac ttggatttat caccacttga cttcaaaccg catatcgctc cacataagtt
     2761 tgagggaatg gtagaaacag ctcgtgactt gattcgtaac ggcgatatgt tccaatgtgt
     2821 actcagccag cgtttctcag cagaagttac tggaaatcca tttgacttct acagaaatct
     2881 ccgcgtaact aatccttcta attaccttta tttctatgat tttggggatt atcaaatcat
     2941 cggagctagt ccagaaagtt tggtttctgt caaaaatggc atcgtgacaa ccaatccgat
     3001 tgcagggacg cgaccaagag gggctacgga tgaagaagac aaggccttgg cgactgacct
     3061 cctctctgat gagaaggaaa cagcagaaca tcgaatgttg gtagacttgg ggcgtaacga
     3121 tattggccgc atctctgaaa cgaccagtgt ccaagtcact aagtatatgg aagtggagct
     3181 cttccgctac gtcatgcatt tgaccagcgt agtcaagggg cgtttgcttg cagaactcac
     3241 tgccatggat gccttgaaag caacgcttcc tgctggaacc gtttctggag caccaaagat
     3301 tcgagcgatg agacgtatct atgaactgga aacggaaaaa cggggagtat acgctggggc
     3361 aatcggctac ttgtctgcga cgggtgatat ggatttggcc atcgccatcc gaaccatgat
     3421 tctcaaaaat caaagagcct atgtgcaggc tggggcaggg attgtctacg actctatcgc
     3481 ccaaaacgaa taccaagaaa ccattaacaa agcaaaatct atgactagaa ttggagaact
     3541 aagaccatga ttttattgat tgacaactat gattctttta cctataactt ggcccaatac
     3601 attgggaatt ttgcagaagt tcaggttctg agaaatgatg attccaagct gtatgaagaa
     3661 gctgaaaaag cagatggtct ggtcttttct cctggtcctg gttggccagt tgatgctgga
     3721 aagatggaag acatgattcg tgattttgca ggcaagaagc cgattcttgg gatttgtttg
     3781 ggccaccaag ccattgcaga agtctttggt ggtaagctag gtttggctcc aaaagtcatg
     3841 catgggaaac agagcaatat caactttgaa gcgccatctg ttttgtatca aggtattgag
     3901 gatggccgtg cggtcatgcg ttatcacagt attttgattg aggaaatgcc agaagacttt
     3961 gaagtgacag ctcgttcgac tgatgaccaa gccatcatgg ggattcaaca taaaaaccta
     4021 ccgatttatg gcttccagta ccatccagag agcattggaa cgccagacgg cttgtcttct
     4081 attcggaatt ttatcgagga ggttgtaaag tgaggaaact aggatgaaag agattattga
     4141 aaaactagca aaatttgaaa atttatcagg tgtggaaatg acggatgtca ttgagcgtat
     4201 cgtaactggg cgtgtaactg aagcgcagat tgcttctctc ctcttagctc ttaagatgaa
     4261 gggggaaaca cctgaagaac gcacagccat tgcccaagtc atgagaggac atgcccagca
     4321 tattccaact gagattcatg atgccatgga caactgtggt acaggtgggg acaagtcttt
     4381 cagttttaat atttccacaa ctgcagcctt tgtcttggct ggtggcggta ttcacatggc
     4441 caaacacggt aaccgctcga tatcttctaa atctggttcc gcagatgtcc tcgaagcctt
     4501 gggaatcaat cttgacctca aaccagctga actaggtaag gtctttgata aaactggaat
     4561 cgtctttctc ttcgctaaaa atatgcaccc agctatgaaa tacatcatgc cagctcgttt
     4621 ggaattggga attccaacga ttatgaactt gactggtcca ctgattcatc caatggcttt
     4681 agaaacacag cttcttggaa ttagtcgtcc agaactccta gaaagtacag ctcaggtttt
     4741 gaaaaatatg ggtcgcaaac gtgccatcgt ggttgctgga ccagaagggt tggatgaagc
     4801 tggcttgaac ggaacaacca agattgcact tcttgaaaat ggcgaaatca gcttgtcaag
     4861 ctttactcca gaggatttgg gaatggaagg ctatgctatg gaagatattc gtggtgggaa
     4921 tgctcaggaa aatgcagaaa ttttgcttag cgttctgaaa aacgaagcaa gtccattctt
     4981 ggaaacgaca gtcttgaatg ctggtcttgg tttctatgct aatggtaaga ttgatagcat
     5041 caaggaagga gttgccttgg ctcgtcaagt gattgctaga ggcaaggccc ttgaaaaact
     5101 cagactgtta caggagtacc aaaaatgagt caggaatttt tagcacgaat cttagagcag
     5161 aaggcgcgtg aggtggagca gatgaagctg gagcaaatcc agcctctgcg ccagacctat
     5221 cgcttggcag aatttttgaa gaatcatcag gaccgcttgc aggtaatcgc tgaggtcaag
     5281 aaagctagcc ctagtttggg agatatcaat ctcgatgtgg atattgtgca acaggcccag
     5341 acttatgaag aaaacggagc agtgatgatt tcggtgttga cagatgaggt tttctttaaa
     5401 gggcatttgg attatctacg ggaaatttcc agtcaggtag agattccgac gctcaacaaa
     5461 gactttatca tcgatgaaaa gcaaatcatc cgcgctcgca atgcaggtgc gacagttatc
     5521 ttgctcattg tggcagcctt gtccgaagaa cgcctcaagg aactgtatga ctacgcgaca
     5581 gagcttggtc tggaagtctt agtggagact cacaatctag ctgaactaga ggtagcccac
     5641 agacttggtg ctgagattat cggggtcaac aaccgcaact tgactacctt tgaggtcgac
     5701 ttgcagacca gtgtagattt agccccttac tttgaggaag gtcgctatta catttctgaa
     5761 tctgccattt tcacagggca ggatgcggaa cgactagccc catactttaa tggaattttg
     5821 gtagggatag ctcttatgca ggcagaaaat gtggtccaga gaatcaagga gttgcagatt
     5881 gacaaaggtt aaaatttgtg gactatcgac caaagaagcg gtggaaacag ccgtttcagc
     5941 aggagccgac tatatcggtt ttgtctttgc acctagtaaa agacaggtga ctttagaaga
     6001 ggcagctgag ttggcaaagc ttattcctgc agatgtgaaa aaggttggag tatttgtttc
     6061 accaagtcgg gtagaactgc tggaagcgat tgacaaagtt ggcttggact tggttcaagt
     6121 tcacggtcag gtagcagatg atttatttga gaatttgcct tgtgccagta ttcaggctgt
     6181 gcaggtagat ggaaatgggc atgtccctaa ttctcaggca gattatctac tctttgatgc
     6241 ccctgtggca ggaagtggcc agccctttga ttggggtcaa ctggatacga ctggactagc
     6301 acagcccttc tttatcgcag gtggccttaa tgaagataat gtagtaaaag caattcaaca
     6361 ctttactccc tatgcagtag atgtatcaag cggagtggag acagatggac aaaaagatca
     6421 tgaaaagatt agaagattta tagagagggt aaagaatggc atatcaagaa ccaaataaag
     6481 atggatttta cggaaaattt ggcggacgtt ttgtcccaga aacattgatg acagcagttt
     6541 tggagttgga gaaggcctac cgtgaaagtc aggcagaccc aagtttccaa gaggaattaa
     6601 accaactttt gcgccagtat gtgggacgtg aaactcccct ttactacgca aaaaacttga
     6661 cccagcatat cggcggagcc aagatttatc tcaaacggga agaccttaac catacaggag
     6721 cccacaagat taacaatgcc ttaggacaag tttggcttgc caaacgcatg ggtaaaaaga
     6781 aaattatcgc agaaactggt gctggtcagc acggtgtggc aactgcaact gctgcggccc
     6841 tctttaacat ggaatgtacc atctacatgg gtgaggaaga tgtcaaacgc caagccctca
     6901 atgtcttccg tatggagctt ttgggagcta aggtcgaggc cgtgacagat ggttcgcgcg
     6961 tgctcaagga tgcggtcaat gcagctcttc gttcatgggt agctaatatc gatgataccc
     7021 actatatcct tggttctgcc ttggggcctc atccatttcc agaaatcgtt cgtgacttcc
     7081 aaagtgtcat cggtcgagag gctaaacaac agtaccgtga cttgacaggt cgagatctgc
     7141 cagatgccct agtagcctgt gttggtggtg ggtcgaatgc tatcgggctc ttccatccct
     7201 ttgtagaaga tgagtcagta gctatgtatg gaactgaagc agcagggctt ggtgtggata
     7261 cagagcacca cgctgctacc ttgaccaagg gtcgtccggg agttcttcac ggttctctca
     7321 tggatgtgct ccaagatgcc catggtcaaa ttcttgaagc cttctctatc tcagcaggtt
     7381 tggactatcc tggtattggt ccagaacatt ctcactacca cgatatcaaa cgtgccagct
     7441 atgtccctgt gacagacgaa gaagccttgg aaggattcca actcttgtct cgtgtggaag
     7501 ggattatccc agccttggaa tctagccatg ctatcgcttt tgcggtgaaa ttggccaaag
     7561 aacttggacc agaaaagtct atgattgtct gcctatcagg tcgtggggac aaggatgtgg
     7621 ttcaagtcaa agaccgcttg gaagcagatg cagcaaagaa gggagaagct catgcctaag
     7681 acactaacag aaaaattaaa tgctataaaa gcagctggaa aaggaatttt tgttccctat
     7741 atcatggctg gagaccacga gaaaggtttg gatggactag gagaaacaat ccactttcta
     7801 gaagatttgg gtgtctctgc aattgaagtg ggtattccct tttcagaccc tgttgcagat
     7861 ggacctgtta tcgaagaagc tggcttgcgc agtttagccc acgggacctc tacccaggct
     7921 ttagttgaaa ccttgaaaac cattgaaaca gagattccac tggtcatcat gacctacttc
     7981 aaccccctct ttcagtacgg tgtggagaac tttgtcaaag atctggctga tacagctgtg
     8041 aagggcttga ttatcccaga cttgcctcat gaacatgcca actttgtaga accatttttg
     8101 gcagatacag atatcgcctt gattccttta gtaagcttga ccacaggaat tgagcgccag
     8161 aaagagttga ttgaaggggc ggagggattc gtctatgccg ttgccatcaa tggagtgaca
     8221 gggaaatcag gcaattaccg tgcagatttg gacaagcact tggcgcaact tcatcaagtg
     8281 gccgacatcc cagtcttgac aggttttggt gtatctagtc aagccgatct ggaacgcttc
     8341 aatgcggtgt cagatggtgt tatcgtcggt tcaaaaatag taaaagctct ccaccaagga
     8401 gagccgattc aggattttat cagacaagca gtagcttacc aaaaataatc aaacaagtag
     8461 caagtaagag gaaaggcacg aaaggaagtc tttccttttt ctttttcagg agaaaggcta
     8521 gttttatagt gaattgaatc tggaatatta cactacggtt cctaaaatat tttaagaaag
     8581 tgatttgaat ttcccaataa atttgttcag tttttaattg attttactat agaagatata
     8641 attttctaaa ttactctgac acagaacttt aagaaaaagc taattattgt agtaatttct
     8701 ttaagaaaat gatataattc attaaaaagt atttggagga ggaagaatta tgttgaatca
     8761 ggatctcttt gattcgcttg aggcacaaaa aattgtagat actttgatga aagggcaaaa
     8821 agattatgta gatgaacgtc tagaaaaaag agagacaatg atagtgtcga atggttatgc
     8881 atggacgcga cctaatcata ttgatactgc atttgcatca gcagatttgt ttgagtataa
     8941 attacaatta gcaggacaga cttggggata tttagaattt gaaacaaata cagaaaaata
     9001 tgggaaagta ttgttaatta taaagggtaa gaagcgactt acgaaccaat ttcctttggt
     9061 acaaaaaaat aagagtggct acttatttga atatgctcag atgaatacac tttatcttaa
     9121 tcaacatgct tcctacaaaa atgatgaaga tagtcattcc tttccaattc agatggagtt
     9181 agtttctgat gaaatgattc aagaaattga acaagctact aaaaattcga atatcgaaaa
     9241 atttatgatt ttaacttatg aggcggactc agaaaacaat attatatctg tagatgttgt
     9301 tatgcctgat gcacgaactg gtcagttaca cttgattcaa gatttgtctg agtatattca
     9361 atcaagttcg taccatttcg aagaagctaa atatcaagat attcctaatt tttcagaatt
     9421 atcggaaaca gaagattttg aaattattcc aagaatagaa aaacaagaag gtcaaaagta
     9481 gtaaggagta tgtaaatgtt taatggtcgg gtattgaaag aattacggct gttaaatggt
     9541 ttaagtagag cagaattagc tcagagaatt aatttaacgg aacaagccat ttggcagttt
     9601 gagtccaacg aaacgaaacc taaattatca accaaaatgc atttggccaa ccaatttcat
     9661 gttgatttaa cttattttga acaggaagaa gagagcattc gatttgattc ttctgtaatt
     9721 gcctttagaa atgcagacct agcaacacgg aaaacaatag atattcaaac tatgtattta
     9781 cataaggtag atagtttgat tgattatttt gaaagttttg taattatacc taatattaca
     9841 attcatgacc taagtaatgt agtgagtgaa tcttatcata agggagaatc cattgaggaa
     9901 ttggctcttt atgccaggga aaaattaggt atttcaaaag ataatcatga tttgctttat
     9961 aaattagaac gttcaggcat ctatatcgtg gaacgattaa ttaatggcca agctgatgct
    10021 tatagcgcat ggtcaaaatt gggaagacct tatattgtgt tgggaacgaa taaatcatct
    10081 gtacgtcgaa attttgactt agctcatgag ctaggacata ttcttttaca taaatataaa
    10141 gatatgaatg aagatggcga tcgtttggag caagaagcaa attattttgc atcatgtttt
    10201 ttattgccaa aagaagagtt tttagtcaaa tttgaagaga gggttggcaa gcgtgtcagc
    10261 aatcctgata attatatttt attgaagtcg gatttgaatg tttcgataca ggctttagag
    10321 tatcgagctt ttaagttagg attattgact ccaaagcaac attcttactt ttatcgtcaa
    10381 attgcgcaaa aaggttacaa aatgattgaa cctttggatg atcaaatttt tgttaaaaaa
    10441 ccaagcaaag taaagagtat tctggacgtc gttttgagta atcatctagt cagtctagcg
    10501 actataatgt ctaaacaaag tattcgttta cagtttataa gcgaaatatt ttcagtcgaa
    10561 atgaaatttt ttgatcagta tcaagaagat agaagaacag atcgatttga taacatcatc
    10621 cctttgtaca aaagaaataa tttataattt aactgtgaaa taatttcatg aaggatatat
    10681 ggcagaaatt ggattttatc agacaagcag tagcttacca aaaataatca aacaagtagc
    10741 aagtaagagg aaaggcacga aaggaagtct ttcctttttc ttttgcagga gaaaggccag
    10801 gatacccgtc gcagaagcaa actgaatcaa gatcagtaac tccgttacgc taaagacgag
    10861 agcacaagaa gctaaaaaga ggaaatctcc tgcgcccatg cggatatcga taaaatgagc
    10921 caaaattcca agagcaagga aggagaccat gaccagattc cagccagagg aagctattag
    10981 gattaggtgg aaagtcatcc agaccagtaa gggatattcc tgatggtgaa agtcgtagat
    11041 acccaaggtc aaaccagcgg tgattaggac gacttgcccc aaggaaagca attcccaaga
    11101 gtaaagcaga aagaggagtc ctaagcctag ttcaaagagg gcataccaga caggatagcg
    11161 aactttgcag tagcgacagc gaaagcgatt gaagacctgt gagagaatcg gaatcaaatc
    11221 taagggacgc aagcgagtct gacaggaatc gcagtgactg gctgaactga taatggattg
    11281 ctctggaaaa cggtcaatga ccaaaccaag aaaggaagcg agaatgctcc cgacgagaaa
    11341 aaaataaaaa tcaatcatac ttatctattc gtaaaaaatg ggagaaatag tataatggag
    11401 aaacatagat aagatggtga ggaaaagatg acaattcgtt ttgaagaaaa ggtgagtata
    11461 gaaaacgctc aatttgtatg ccaatggtcc aactccctag gcaaatcctt tcaagaacaa
    11521 tggatgggac caaggattcc ttttctactg acccttcaag ccttggaaga agtattttca
    11581 atctttgatg aacaagagtt tgtgggcctt atccagaaaa tcaggctaga agacagcaat
    11641 cttcatatcg ggagattttt tatcaacccc cagaaacagg ggcaaggctt aggtagccag
    11701 actttaagga aatttgttag tttggccttt gaaaatgaag atatagataa tatttctcta
    11761 aatgtcttcg aggcaaatca aagagctcag aatctttacc aaaaagaagg atttgaaatc
    11821 gttcaaatgg ttgaagcacc tgtacgaaaa tatagtggat tgaaactaga atagtacacc
    11881 tctacttc
//
LOCUS       DAVKAU010000055        11487 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVKAU010000055 DAVKAU010000000
VERSION     DAVKAU010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11487
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.055"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..446
                     /locus_tag="VWX48_001739"
                     /pseudo
     CDS             1..446
                     /locus_tag="VWX48_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            601..801
                     /locus_tag="VWX48_001740"
     CDS             601..801
                     /locus_tag="VWX48_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172322.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRVLSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            843..1247
                     /locus_tag="VWX48_001741"
     CDS             843..1247
                     /locus_tag="VWX48_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172323.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1478..2185
                     /gene="ccdA2"
                     /locus_tag="VWX48_001742"
     CDS             1478..2185
                     /gene="ccdA2"
                     /locus_tag="VWX48_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9172324.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2196..2753
                     /gene="sdbB"
                     /locus_tag="VWX48_001743"
     CDS             2196..2753
                     /gene="sdbB"
                     /locus_tag="VWX48_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU9172325.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3128..4519
                     /locus_tag="VWX48_001744"
     CDS             3128..4519
                     /locus_tag="VWX48_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU9172326.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4662..5579
                     /gene="adcAII"
                     /locus_tag="VWX48_001745"
     CDS             4662..5579
                     /gene="adcAII"
                     /locus_tag="VWX48_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU9172327.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5587..8103
                     /gene="phtD"
                     /locus_tag="VWX48_001746"
     CDS             5587..8103
                     /gene="phtD"
                     /locus_tag="VWX48_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU9172328.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPVQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFEVLDNLLERLKDVSSDKVKLVDDILAFLAPIRHP
                     ERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWI
                     KKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPLDRM
                     PYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHP
                     NERPHSDNGFGNASDHVRKNKADQDSKPDEDKGHDEVSEPTHPESDEKENHAGLNPSA
                     DNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIADAEALLEKVTDPSIRQNAM
                     ETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPAPIQ"
     gene            8313..11432
                     /gene="phtE"
                     /locus_tag="VWX48_001747"
     CDS             8313..11432
                     /gene="phtE"
                     /locus_tag="VWX48_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU9172329.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKIDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEEVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQQSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         3799 a         2044 c         2373 g         3271 t
ORIGIN      
        1 tgacaatcca gacgcttatt tgactgaaat agcttctgaa tttggctgtc atccaactac
       61 catccactat gcgctcaaag ctatgggcta cactcgaaaa aaagaaccac acctactatg
      121 aacaagaccc agaaaaagca gccttatttc ttaagaattt taatagttta aagcacctag
      181 cacctgttta gattgatgaa acaggattcg atacttattt ttatcgagaa tatggtcgct
      241 cattaaaagg tcagttaaga agaggcaaag tatctggaag aagatatcag aggatttctt
      301 tggttgcagg tctaacaaat ggtgagttaa tcgttccaat gacttacgaa gagacgatga
      361 cgagcgactt ttttgaagct tggtttcaga agtttttctt accaacatta accacaccat
      421 cggttattat agtaaaacga aataagaata ggacaaatcg atcaggacag taaaatcgaa
      481 ttctaacaat gttttagaag tccatatgta ctattctagt ttcaatatac cataactgct
      541 cctagtcaac ctgcaagtcc tggcccagct ccaagctcag ctccgactca agatcctaga
      601 gtggtagcaa gcgcttcggc tagctcaacg agcacacaag ctcaagagca agttgacaag
      661 tctgaacttc gtgtcttgag tcaagagtta gaccaacgct tgaaagcttt ggcaacagta
      721 tctgatccga aaatcgatgc aaccaaggct gtcctcctag atgctcaaaa agctccggaa
      781 gatagtgcct tgacagagta aggtctgcat actgcagtag agtctgtgaa ggctgggctg
      841 ccttggactc tctcaaagat gtgaaagcaa atgctagcga cagcaagcct gcacaggaca
      901 agaaggatgc aaaacaagga acggaagata gtaaggattc agataagatg actgaaacaa
      961 actcagttcc ggcaggagtg attgtggtca gtctacttgc cctcctaggc gtgattgcct
     1021 tctggctgat tcgccgtaag aaagagtcag aaatccagca attaagcacg gaattgatca
     1081 aggttctagg acagctagat gcagaaaaag cggataaaaa agtccttgcc aaagcccaaa
     1141 accttctcca agaaaccctt gatttcgtga aagaagaaaa tggctcagca gagacagaaa
     1201 ctaaactagt agaggagctt aaagcaatcc ttgacaaact caagtaaaac atgatttatg
     1261 aaatgtcaga cctaaaagac attttcgttc acaaaagcag cgatgagtaa tccttgtcgt
     1321 tgctttttgg ctattttggg ggataagatc cgccttgact agcaaaagaa aagattggtc
     1381 caatagtgcc cgatacgatt ttgcgtagca gaaagcttac aaataaaatt gaatatagta
     1441 aaataggatt agaattatta agaaagttgg ttctttattg gaaacgatag tatttttaat
     1501 ctctgttttt ctagcaggtg ttttatcctt tttttctcct tgtatttttc ctcttctgcc
     1561 agtctatgct gggattttat tggatgatca agaaagtgca aaaagctttt ctttgtttgg
     1621 gagaaaggtt ctctggtcag gcttgattcg aacactttgc tttatcgctg gtatctctct
     1681 cattttcttt attctaggct ttggtgctgg ttactttggt catattctct atgcaaattg
     1741 gtttcgatat gtcatgggag ctattattat cattttgggt cttcaccaga tggaaatttt
     1801 tcatttgaag aaattagaag ttcaaaaaag ttttaccttt aaaaaatcag attctaatcg
     1861 ttattggtca gcttttttac ttggtattac ctttagcttt ggttggacac cttgtattgg
     1921 tccagtttta agttctgttt tagcacttgc ggcttctgga ggcaatggtg cttggcaagg
     1981 agcgatttat actctcattt acactctggg catggccctt cctttcttgg tcttggcact
     2041 agcttcaggt ctagtcatgc catattttag taaaatcaag cgtcatatga tgctactaaa
     2101 gaaaattggt ggtttcctca ttgttttaat gggaattttg ttactattag gacaagtaaa
     2161 tgttctagct ggaatttttg aataaaggag gacaaatgaa aaaagtaatg tttgctggct
     2221 taagtctctt gtcattagtt gtattgatgg cctgtggtga ggaagaaact aaaaagactc
     2281 aagcagcaca acagccaaaa caacaaacga ctgtacaaca aattgctgtt ggaaaagatg
     2341 ctccagactt cacattgcaa tccatggatg gcaaagaagt taagttatct gattttaagg
     2401 gtaaaaaggt ttacttgaag ttttgggctt catggtgtgg tccatgcaag aaaagtatgc
     2461 cagagttgat ggaactagcg gcgaaaccag atcgtgattt cgaaattctt actgtcattg
     2521 caccaggaat tcaaggtgaa aaaactgttg agcaattccc acaatggttc caggaacaag
     2581 gatataagga tatcccagtt ctttatgata ccaaagcaac caccttccaa gcttatcaaa
     2641 ttcgaagcat tcctacagaa tatttaattg atagccaagg aaagattgga aagattcaat
     2701 ttggtgctat cagtaatgcg gatgcagaag cagcatttaa agaaatgaac tagaatcgat
     2761 aaaatctgat tacaagatgt agtcagattt tggtaacttc taaaactaac ttctagtttc
     2821 ccacaaccta gcttttagta tgagaaaaac gtgtgacacc agtggaaatc cgtcttagac
     2881 taacttccac tggttttctt tttcttgata tataagggtt caaaagcgaa aagactcaga
     2941 aaaaagtgca cgacaaatag ccctaaaaca gagtcgtttt agagtaactt ccagttttgg
     3001 gagagagatg gaagttactt tgagaagtta cggtagtcag atttttttag aaaaacattt
     3061 tataaatatt cacatatctc ctatatttat ggtaaaatag aatcatcagt ttattttgga
     3121 gtcaaagatg aatatattta gaacaaagaa tgttagttta gataaaacag agatgcatag
     3181 gcatttgaag ttatgggatt tgattttgct gggtattgga gccatggtag ggacaggtgt
     3241 ctttacaatc acaggtactg cagctgctac acttgctggt ccagcactag tgatttcaat
     3301 cgttatttct gccttgtgtg tgggattatc agccctcttt tttgcagaat ttgcctcgcg
     3361 agtacccgct acaggaggtg cctatagtta cctctatgct atcttaggag aattccctgc
     3421 ctggttggct ggttggttaa ccatgatgga gttcatgaca gccatatcag gcgtagcttc
     3481 gggttgggca gcttatttta aaggcttgct ctctcaatac gggatagccc ttcctcaggc
     3541 tttaaatggt acctttaatc ctcaagcagg gacatttgtt gatttattgc ctattcttgt
     3601 cttggtcttg gtgacttcgc ttgttttact aaatgccaag gcagccttac gctttaattc
     3661 gattctagtt attttgaaat tttccgcttt agctctcttt gttttagtag gaatttggaa
     3721 tattaagttt gataattgga gcaattttgc tccttacggt tttggacaaa tctatggagc
     3781 tagtactggt attatggctg gtgcgtcctt gatgttcttc ggttttttgg gatttgaatc
     3841 catctctatg gctgtagatg aagtcaagac tcctcaaaaa aatattccta gagggattgt
     3901 cttatcgctt tctatcgtaa ccattctcta tgccttggtg acccttgttt tgactggtgt
     3961 ggttcactat agtcatttaa atgtcgatga tgccgttgcc tttgcccttc gtagtgttgg
     4021 gattagttgg gcagccaact atgtgtcatt agtggctatc ttgaccttga ttacagtttg
     4081 tatttcgatg acctatgccc tatcgcgtat gatttacagt ttagcacgtg acggcttagt
     4141 gcctgctgcc tttaaggaac tgacgaagac tagcaagata ccaaagaatg ctactatctt
     4201 gacaggtcta gcttcagcag tagcagcagg aatgttccca ctagccagta ttgcagcctt
     4261 tttaaatatt tgtaccttag cctacttgat catgctggct tatggtctga ttcgcttacg
     4321 gaaagaaaaa ggaatgccca aagctgggga atttaaaaca ccattggtac ctctgttacc
     4381 aattttatcg atcatcattt gtttatcctt catgttacag tataatatga acacctggat
     4441 tgctttccta gttgcgttgt tagtaggaag tattatttac ttcacttatg gctataagca
     4501 ttctaccata gaagaataaa gtgaaagtct attgagttgt tgacactcag tagattttta
     4561 tatgtgaaag aaatttcaaa ttttttctaa aaatatcttg acagattaaa ttttcaggag
     4621 tagaatattt actagttaat taaatggtta aggagttgtt catgaagaaa caaaatttat
     4681 ttttagtcct gttaagtgtc tttcttttgt gcttgggggc ttgtggtcaa aaggaaagtc
     4741 agacaggaaa ggggatgaaa attgtgacca gtttttatcc tatctacgct atggttaagg
     4801 aagtatctgg tgacttgaat gatgttcgga tgattcagtc aagtagtggt attcactcct
     4861 ttgaaccttc ggcaaatgat atcgcagcca tctatgatgc agatgtcttt gtttaccatt
     4921 ctcatacact cgaatcttgg gcaggaagtc tggatccaaa tctaaaaaaa tccaaagtga
     4981 aggtcttaga ggcttctgag ggaatgacct tggaacgtgt ccctggacta gaggatgtgg
     5041 aagcagggga tggagttgat gaaaaaacgc tctatgaccc tcacacatgg ctagatcctg
     5101 aaaaagctgg agaagaagcc caaattatcg ctgataaact ttcagaggtg gatagtgagc
     5161 ataaagagac ttatcaaaaa aatgcgcaag cctttatcaa aaaagctcag gaattgacta
     5221 agaaattcca accaaaattt gaaaaagcga ctcagaaaac atttgtaaca caacatacag
     5281 ccttttctta tctagcgaag agatttgggc ttaatcaact tggtattgca ggcatctctc
     5341 ctgaacaaga accaagtcca cgacaattaa cagaaattca ggaatttgtt aaaacctata
     5401 aggttaaaac gatttttaca gaaagtaatg cttcttcaaa agtagctgaa actcttgtca
     5461 aatcaacagg tgtgggtctt aaaactctga atcctttaga ggcagaccca caaaatgaca
     5521 agacctattt agaaaatctg gaagaaaata tgagtgttct agcagaagaa ttaaagtgag
     5581 gaaagaatga aaatcaataa aaaatatcta gcaggttcag tggcagtcct tgccctaagt
     5641 gtttgttcct atgaacttgg tcgtcaccaa gctggtcagg ttaagaaaga gtctaatcga
     5701 gtttcttata tagatggtga tcaggctggt caaaaggcag aaaatttgac accagatgaa
     5761 gtcagtaaga gagaggggat caacgccgaa caaattgtta tcaagattac ggatcaaggt
     5821 tatgtgacct ctcatggaga ccattatcat tactataatg gcaaggttcc ttatgatgcc
     5881 atcatcagtg aagaacttct catgaaagat ccgaattatc agttgaagga ttcagacatt
     5941 gtcaatgaaa tcaagggtgg ctatgtgatt aaggtagacg gaaaatacta tgtttacctt
     6001 aaagatgcgg cccatgcgga caatattcgg acaaaagaag agattaaacg tcagaagcag
     6061 gaacacagtc ataatcataa ctcaagagca gataatgctg ttgctgcagc cagagcccaa
     6121 ggacgttata caacggatga tgggtatatc ttcaatgcat ctgatatcat tgaggacacg
     6181 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
     6241 tcagctagcg agttagctgc tgcagaagcc tattggaatg ggaagcaggg atctcgtcct
     6301 tcttcaagtt ctagttataa tgcaaatcca gttcaaccaa gattgtcaga gaaccacaat
     6361 ctgactgtca ctccaactta tcatcaaaat caaggggaaa acatttcaag ccttttacgt
     6421 gaattgtatg ctaaaccctt atcagaacgc catgtagaat ctgatggcct tattttcgac
     6481 ccagcgcaaa tcacaagtcg aaccgccaga ggtgtagctg tccctcatgg taaccattac
     6541 cactttatcc cttatgaaca aatgtctgaa ttggaaaaac gaattgctcg tattattccc
     6601 cttcgttatc gttcaaacca ttgggtacca gattcaagac cagaacaacc aagtccacaa
     6661 tcgactccgg aacctagtcc aagtctgcaa cctgcaccaa atcctcaacc agctccaagc
     6721 aatccaattg atgagaaatt ggtcaaagaa gctgttcgaa aagtaggcga tggttatgtc
     6781 tttgaggaga atggagtttc tcgttatatc ccagccaagg atctttcagc agaaacagca
     6841 gcaggcattg atagcaaact ggccaagcag gaaagtttat ctcataagct aggagctaag
     6901 aaaactgacc tcccatctag tgatcgagaa ttttacaata aggcttatga cttactagca
     6961 agaattcacc aagatttact tgataataaa ggtcgacaag ttgattttga ggttttggat
     7021 aacctgttgg aacgactcaa ggatgtctca agtgataaag tcaagttagt ggatgatatt
     7081 cttgccttct tagctccgat tcgtcatcca gaacgtttag gaaaaccaaa tgcgcaaatt
     7141 acctacactg atgatgagat tcaagtagcc aagttggcag gcaagtacac aacagaagac
     7201 ggttatatct ttgatcctcg tgatataacc agtgatgagg gggatgccta tgtaactcca
     7261 catatgaccc atagccactg gattaaaaaa gatagtttgt ctgaagctga gagagcggca
     7321 gcccaggctt atgctaaaga gaaaggtttg acccctcctt cgacagacca tcaggattca
     7381 ggaaatactg aggcaaaagg agcagaagct atctacaacc gcgtgaaagc agctaagaag
     7441 gtgccacttg atcgtatgcc ttacaatctt caatatactg tagaagtcaa aaacggtagt
     7501 ttaatcatac ctcattatga ccattaccat aacatcaaat ttgagtggtt tgacgaaggc
     7561 ctttatgagg cacctaaggg gtatactctt gaggatcttt tggcgactgt caagtactat
     7621 gtcgaacatc caaacgaacg tccgcattca gataatggtt ttggtaacgc tagcgaccat
     7681 gttcgtaaaa ataaggcaga ccaagatagt aaacctgatg aagataaggg acatgatgaa
     7741 gtaagtgagc caactcaccc tgaatctgat gaaaaagaga atcacgctgg tttaaatcct
     7801 tcagcagata atctttataa accaagcact gatacggaag agacagagga agaagctgaa
     7861 gatactacag atgaggctga aattcctcaa gtagagcatt ctgttattaa cgctaagata
     7921 gcagatgcgg aggccttgct agaaaaagta acagatccta gtattagaca aaatgctatg
     7981 gagacattga ctggtctaaa aagtagtctt cttctcggaa cgaaagataa taacactatt
     8041 tcagcagaag tagatagtct cttggctttg ttaaaaaaaa gtcaaccggc tccgatacag
     8101 tagtaaaatg aatggagcat attttatgga gaagtaacct ttcgtgttac ttctcttttt
     8161 tagaaaaatg taacagaaac ttgacaaaag taattttaaa tagtaaacta tttactggtt
     8221 aattaaatgg ttaaataacc ggtttagaaa actatttaat aaagtaaaag aagttgagaa
     8281 aaaacttcat catttattga aatgagggat ttatgaaatt tagtaaaaaa tatatagcag
     8341 ctggatcagc tgttatcgta tccttgagtc tatgtgccta tgcactaaat cagcatcgtt
     8401 cgcaggaaaa taaggacaat aatcgtgtct cttatgtgga tggcagccag tcaagtcaga
     8461 aaagtgaaaa cttgacacca gaccaggtta gccagaaaga aggaattcag gctgagcaaa
     8521 ttgtaatcaa aattacagat cagggctatg taacgtcaca cggtgaccac tatcattact
     8581 ataatgggaa agttccttat gatgccctct ttagtgaaga actcttgatg aaggatccaa
     8641 actatcaact taaagacgct gatattgtca atgaagtcaa gggtggttat atcatcaaga
     8701 tcgatggaaa atattatgtc tacctgaaag atgcagctca tgctgataat gttcgaacta
     8761 aagatgaaat caatcgtcaa aaacaagaac atgtcaaaga taatgaggag gttaactcta
     8821 atgttgctgt agcaaggtct cagggacgat atacgacaaa tgatggttat gtctttaatc
     8881 cagctgatat tatcgaagat acgggtaatg cttatatcgt tcctcatgga ggtcactatc
     8941 actacattcc caaaagcgat ttatctgcta gtgaattagc agcagctaaa gcacatctgg
     9001 ctggaaaaaa tatgcaacag agtcagttaa gctattcttc aacagctagt gacaataaca
     9061 cgcaatctgt agcaaaagga tcaactagca agccagcaaa taaatctgaa aatctccaga
     9121 gtcttttgaa ggaactctat gattcaccta gcgcccaacg ttacagtgaa tcagatggcc
     9181 tggtctttga ccctgctaag attatcagtc gtacaccaaa tggagttgcg attccgcatg
     9241 gcgaccatta ccactttatt ccttacagca agctttctgc cttagaagaa aagattgcca
     9301 gaatggtgcc tatcagtgga actggttcta cagtttctac aaatgcaaaa cctaatgaag
     9361 tagtgtctag tctaggcagt ctttcaagca atccttcttc tttaacgaca agtaaggagc
     9421 tctcttcagc atctgatggt tatattttta atccaaaaga tatcgttgaa gaaacggcta
     9481 cagcttatat tgtaagacat ggtgatcatt tccattacat tccaaaatca aatcaaattg
     9541 ggcaaccgac tcttccaaac aatagtctag caacaccttc tccatctctt ccaatcaatc
     9601 caggaacttc acatgagaaa catgaagaag atggatacgg atttgatgct aatcgtatta
     9661 tcgctgaaga tgaatcaggt tttgtcatga gtcacggaga ccacaatcat tatttcttca
     9721 agaaggactt gacagaagag caaattaagg ctgcgcaaaa acatttagag gaagttaaaa
     9781 ctagtcataa tggattagat tctttgtcat ctcatgaaca ggattatcca agtaatgcca
     9841 aagaaatgaa agatttagat aaaaaaatcg aagaaaaaat tgctggcatt atgaaacaat
     9901 atggtgtcaa acgtgaaagt attgtcgtga ataaagaaaa aaatgcgatt atttatccgc
     9961 atggagatca ccatcatgca gatccgattg atgaacataa accggttgga attggtcatt
    10021 ctcacagtaa ctatgaactg tttaaacccg aagaaggagt tgctaaaaaa gaagggaata
    10081 aagtttatac tggagaagaa ttaacgaatg ttgttaattt gttaaaaaat agtacgttta
    10141 ataatcaaaa ctttactcta gccaatggtc aaaaacgcgt ttcttttagt tttccgcctg
    10201 aattggagaa aaaattaggt atcaatatgc tagtaaaatt aataacacca gatggaaaag
    10261 tattggagaa agtatctggt aaagtatttg gagaaggagt agggaatatt gcaaactttg
    10321 aattagatca accttattta ccaggacaaa catttaagta tactatcgct tcaaaagatt
    10381 atccagaagt aagttatgat ggtacattta cagttccaac ctctttagct tacaaaatgg
    10441 ccagtcaaac gattttctat cctttccatg caggggatac ttatttaaga gtgaaccctc
    10501 aatttgcagt gcctaaagga actgatgctt tagtcagagt gtttgatgaa tttcatggaa
    10561 atgcttattt agaaaataac tataaagttg gtgaaattaa attaccgatt ccgaaattaa
    10621 accaaggaac aaccagaacg gccggaaata aaattcctgt aaccttcatg gcaaatgctt
    10681 atttggacaa tcaatcgact tatattgtgg aagtacctat cttggaaaaa gaaaatcaaa
    10741 ctgataaacc aagtattcta ccacaattta aaaggaataa agcacaagaa aactcaaaac
    10801 ttgatgaaaa ggtagaagaa ccaaagacta gtgagaaggt agaaaaagaa aaactttctg
    10861 aaactgggaa tagtactagt aattcaacgt tagaagaagt tcctacagtg gatcctgtac
    10921 aagaaaaagt agcaaaattt gctgaaagtt atgggatgaa gctagaaaat gtcttgttta
    10981 atatggacgg aacaattgaa ttatatttac catcgggaga agtcattaaa aagaatatgg
    11041 cagattttac aggagaagca cctcaaggaa atggtgaaaa taaaccatct gaaaatggaa
    11101 aagtatctac tggaacagtt gagaaccaac caacagaaaa taaaccagca gattctttac
    11161 cagaggcacc aaacgaaaaa cctgtaaaac cagaaaactc aacggataat ggaatgttga
    11221 atccagaagg gaatgtgggg agtgacccta tgttagatcc agcattagag gaagctccag
    11281 cagtagatcc tgtacaagaa aaattagaaa aatttacagc tagttacgga ttaggtttag
    11341 atagtgttat attcaatatg gatggaacga ttgaattaag attgccaagt ggagaagtga
    11401 taaaaaagaa tttatctgat ctcatagcgt aaggaatagc agtagaaaaa gtctgaatca
    11461 aaaatgaagt tctctcaaaa gttagaa
//
LOCUS       DAVKAU010000056        11162 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVKAU010000056 DAVKAU010000000
VERSION     DAVKAU010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.056"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            70..450
                     /locus_tag="VWX48_001748"
     CDS             70..450
                     /locus_tag="VWX48_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172330.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGSFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPYVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            656..934
                     /locus_tag="VWX48_001749"
     CDS             656..934
                     /locus_tag="VWX48_001749"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172331.1"
                     /translation="MRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKLKEST
                     QKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            985..1677
                     /locus_tag="VWX48_001750"
     CDS             985..1677
                     /locus_tag="VWX48_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU9172332.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1730..4141
                     /locus_tag="VWX48_001751"
     CDS             1730..4141
                     /locus_tag="VWX48_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9172333.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GSERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDENLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKISTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4391..5092
                     /locus_tag="VWX48_001752"
     CDS             4391..5092
                     /locus_tag="VWX48_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172334.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPAQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5094..7802
                     /locus_tag="VWX48_001753"
     CDS             5094..7802
                     /locus_tag="VWX48_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9172335.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMETTANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ANVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQIGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7898..8389)
                     /gene="tpx"
                     /locus_tag="VWX48_001754"
     CDS             complement(7898..8389)
                     /gene="tpx"
                     /locus_tag="VWX48_001754"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU9172336.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8512..9441)
                     /gene="psaA"
                     /locus_tag="VWX48_001755"
     CDS             complement(8512..9441)
                     /gene="psaA"
                     /locus_tag="VWX48_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU9172337.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9473..10321)
                     /locus_tag="VWX48_001756"
     CDS             complement(9473..10321)
                     /locus_tag="VWX48_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9172338.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10318..11040)
                     /locus_tag="VWX48_001757"
     CDS             complement(10318..11040)
                     /locus_tag="VWX48_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9172339.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKTKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3282 a         2068 c         2541 g         3271 t
ORIGIN      
        1 gaaaatactt tttttaaaag caaatatgat acaattttat ttgaaaaaaa taaaaaagga
       61 gattttatta tgaaattaaa aacacttgct ttaattagtg gtatcgtcgg tcttgtggga
      121 ggaattttac ttcttattgg ttcttttgtc ttgttgggaa cagcggtaaa tacagctgct
      181 acaactctta atggaggagc tactgcaggg gctttttcag gtgttgcctt actcttgaat
      241 gccttgaaga ttgcaaatct tgttcttggt atcattgcta ttgtttacta taaaggagat
      301 aagcgtgtag gtgcagctcc gtatgtacta atgattgttt ctggtggagt tagtctcatt
      361 ccattcttag gatgggttgg ggggattctt gctattatcg gaggatctct gttccttgca
      421 acattgaaga aattcaaatc agaagaataa aaggtatttt agcatgaaaa gaacaaaaaa
      481 gtttatcggt ataggagtag ctctattatc tctttctctt ctagttgcat gtggaacata
      541 aagttcaaag aatacttcaa caagtaatga tgagaagaca gtagcaacat ccaatagttc
      601 aaaagaaaca atcactttcg atacaccggt tgtaacagac gatgcgattg aatcaatgcg
      661 cacttatgca gattatatag atctttataa aaatattttt gatgattatt ttactaaagc
      721 tgaggaaggt ttcaaaggca cagctatgga aaataatgac tcgtttacta aactaaaaga
      781 gtcaactcaa aaattattcg atgcgcagaa aaaaaggtta aataatgaag atagaataga
      841 aacaaccaaa aacaatgtga ttgccaaaca ttgtcaaaca gtcctttcct ttttggtttt
      901 gactagcttt tttgtgaaaa attgtgtaaa atagaataga taaacgaggg gaaacctcgg
      961 aaaatttaaa ggagaatcca tctaatggta aaattggttt ttgctcgcca cggtgagtct
     1021 gaatggaaca aagctaacct tttcactggt tgggctgatg ttgatttgtc tgaaaaaggt
     1081 acacaacaag cgattgacgc tggtaaattg atcaaagaag ctggtatcga atttgaccaa
     1141 gcttacactt cagtattgaa acgtgctatc aaaacaacta acttggctct tgaagcttct
     1201 gaccaattgt gggttccagt tgaaaaatca tggcgcttga acgaacgtca ctacggtggt
     1261 ttgactggta aaaacaaagc tgaagctgct gaacaatttg gtgatgagca agttcacatc
     1321 tggcgtcgtt catacgatgt attgcctcca aacatggacc gtgatgatga gcactcagct
     1381 cacacagacc gtcgttacgc ttcacttgac gactcagtta tcccagatgc tgaaaacttg
     1441 aaagtgactt tggaacgtgc tcttccattc tgggaagata aaatcgctcc agctcttaaa
     1501 gatggtaaaa acgtattcgt aggagctcac ggtaactcaa tccgtgccct tgtaaaacac
     1561 atcaaaggtt tgtcagatga cgagatcatg gacgtggaaa tccctaactt cccaccattg
     1621 gtattcgaat tcgacgaaaa attgaacgtc gtttctgaat actaccttgg aaaataaaaa
     1681 attgtaagcc taggattgat ttctaggctt tttatgttag tatggaagta tgataaggaa
     1741 taaaaaacaa gattatgtac tggcctacaa gcaaccagct tcaaccactt acatgggttg
     1801 ggaagaagaa gctttaccga taggtaatgg ttctttagga gcaaaagtat ttggccttat
     1861 agggtctgaa cggattcaat ttaatgaaaa aagtctctgg tctggaggtc cacttcctga
     1921 tagttcagat tatcagggtg gaaatcttca ggatcagtat gtttttttag ctgagattcg
     1981 gcaggctttg gagaagagag attacaatct ggctaaggaa ctggctgagc agcacctaat
     2041 tgggccaaaa acgagtcaat atgggaccta tctgtctttt ggggatattc acattgagtt
     2101 cagccagcaa ggtacgactt tgtctcaggt gacggactat cagagacagt tgaatattag
     2161 taaggcactt gcgacgactt cttatgtcta taagggaacg cgatttgaac gtgaagcttt
     2221 tgcgagtttt ccagatgatc tcttggttca atgttttact aaggaagggt tggaaactct
     2281 agattttact atagaactat ccttgacctg tgatttggct tctgatggaa agtatgagca
     2341 ggaaaaatct gattacaagg agtgtaagtt ggatattact gattctcata tcttgatgaa
     2401 gggaagagtt aaggataatg atctgcggtt tgctagttat ctagcttggg aaacggatgg
     2461 agatattaga gtttggtcag atagggttca gatatcagga gccagttatg ccaatctctt
     2521 cttggccgct aagacggatt ttgcccaaaa tcctgctagc aattatcgca agaaactaga
     2581 tttagagcaa caggtgatag acttggtgga cacagctaaa gaaaagggct atacccaatt
     2641 gaaatcaagg catatcgagg actaccaagc cttattccag cgtgttcaat tggatttgga
     2701 agctgatgtt gacgcatcca ctacagatga tttgttaaaa aattataagc cacaagaagg
     2761 gcaggctttg gaggagctgt tcttccagta tggacggtat ttattgatta gttcgtccag
     2821 agactgccca gatgctctac cagctaacct acagggagtc tggaatgcgg tcgacaatcc
     2881 tccttggaat tcggactatc acttaaatgt caatctgcag atgaattatt ggccagccta
     2941 tgttaccaat ctcctagaga cggtctttcc agtcatcaac tatgtagatg atttgcgtgt
     3001 ctatggtcgt ctagcggctg taaagtatgc aggaatcgtc tctcagaaag gtgaggaaaa
     3061 tggttggttg gttcatactc aagcgactcc ctttggttgg acggcacctg gttgggatta
     3121 ctattggggt tggtcaccag ctgccaatgc gtggatgatg caaaccgttt atgaagccta
     3181 ttcattttat agggaccaag actatcttag ggagaaaatt tatcccatgt tgagggaaac
     3241 ggttcgtttt tggaatgcct ttttacataa ggatcagcag gcgcagcgtt gggtgtcttc
     3301 tccgtcttat tctccagaac atgggccgat ttcgattggc aatacctatg accaatctct
     3361 gatttggcag ttatttcatg attttattca ggctgctcag gaattgggac tggatgagaa
     3421 cttgttgact gaggttaagg agaagtctga tttactaaat cctttgcaaa tcactcaatc
     3481 tggtcgaatc agggagtggt atgaggagga agagcagtat tttcaaaatg agaaagtgga
     3541 ggcccagcac cggcacgctt cccatctagt gggactctat cctggcaatc tctttagcta
     3601 caagggacaa gagtatattg aagcggcgcg tgctagcctc aatgatcgtg gagatggcgg
     3661 cacaggctgg tccaaggcta ataagatcaa tctctgggcg cgtttgggag atggcaatcg
     3721 agcccataaa ttattggcag agcagttaaa gatatccacc ttgccaaatc tttggtgtag
     3781 ccatcctcct tttcagatag atggtaattt tggtgctact agtggcatgg cagaaatgtt
     3841 actccagtct catgcagctt atctggtacc tctagctgcc ctacctgatg cttggtcaac
     3901 aggttctgtt tcaggcttaa tggcacgtgg acattttgaa gtgagcatga gctgggaaga
     3961 taaaaaactc ttacagttga ccattttatc aaggagtgga ggagatttgc gagtttctta
     4021 tccagatatt gagaagagtg tgattaaaat gaatcaagaa aaaataaaag cgaaatgcat
     4081 ggggaaagat tgtatttcgg tggcaacagc agaaggtgat cttgttcaat tttattttta
     4141 agaagatgtt ataaggcagt aatttgaaac tgccttttaa taaggattta agaatatagg
     4201 cagtttccaa ctagttgaaa aagcgttata atgataatag gaagtaatac tcaatgaaaa
     4261 tcaaagagca caaactagga agctagccgc aggttgctca aaacagtgtt ttgaggttgt
     4321 agatggaagc tgacgtggtt tgaagagaga ttttcgagga gtataatttg tttgatagag
     4381 ggtgggtctg atggcttata ttgagatgaa acactgttac aagcgttatc aggttgggga
     4441 cacggagatt gtggccaatc gtgatgtgaa ttttgagatt gaaaaggggg agctggttat
     4501 tatccttggt gcttcaggtg caggcaagtc aacagttctt aaccttcttg ggggaatgga
     4561 taccaatgat gaaggggaaa tctggattga tggtgttaat attgcggatt atagttccca
     4621 ccagcgcacc aattaccgta gaaatgatgt ggggtttgtt tttcagtttt ataatctagt
     4681 ttctaatctg acagctaagg aaaatgtgga actggcttct gaaattgtga cagatgcctt
     4741 gaatcctgct caggttttga cagatgtagg tctggctcat cgtctcaata actttccagc
     4801 ccagctttct ggaggggagc aacagcgagt ctccattgca cgcgcggtag ccaaaaatcc
     4861 taaaattctt ctttgtgatg aaccgactgg agccttggat tatcagacgg gcaagcaggt
     4921 tttgaaaatt ctccaagata tgtctcgtca aaagggagcg acggtgatca tcgtgactca
     4981 taatggagct ttggcgccca ttgctgatcg cgtgattcat atgcacgatg ccagtgtcaa
     5041 ggatgtggtg ctcaaccagc atcctcagga tattgacagt ttggagtact agcatgatca
     5101 agcgaaaaac ttattggaag gacttaattc agtccttcac aggctccaag gggcgttttt
     5161 tatccatctt gatcctgatg atgttgggat ctctagcctt agtaggcctc aaagtaacca
     5221 gtcccaacat ggagacgaca gctaatgctt atttaacaac tgctcaaacc ttggatttgg
     5281 cagtcatgtc taactatggc ttggatcaag cagaccaaga agaactaaaa cagacggagg
     5341 gcgcagaggt cgagtttggc tatttgacag atgtgactat ggataatggg caggatgcca
     5401 ttcggctgta ctccaaacca gagcgaattt caacctttca gctaagaaag ggacgacttc
     5461 ctcagtcaga caaggaaatc gctttggcca ctcatttgca aggccaatac agcgtgggac
     5521 aggagattag ttttaaagaa aaagaagagg gtcattcctc tttaaaagac catacttata
     5581 ccattactgg ttttgtggat tcggctgaaa tcctctccca gcgagatatg ggctacgcag
     5641 gaagtggaag tgggactctg acagcctatg gggtgatttt acctagtcaa tttgatcaga
     5701 aagtctacaa tatagctcgt ttgaaatatc aagatttagc aggtttaaat gccttttcat
     5761 cagcttatga agaaaaatcc aagcaacatc aggaagagct tgaacaaatt ttatcagata
     5821 atggcaaggt acgtctgcaa cttttgaaaa aagaaggaca agagtctcta gacaaggggc
     5881 aagagaccct tgacaaggct cagactaatt tgcaggaagg caagcgtcgt ttagcagctg
     5941 ctcaagctcg tatacaggct caagaaagtc aactagcctt gtttcctcaa gttcagagag
     6001 agcaggctag tgctcaactt acccaagcca agcaggaatt gggcaaggaa gaggccaaac
     6061 taaagcaagc tgaacaaaat ctagcccaag aaaaggaaaa attagaaaaa catcagcaag
     6121 tcttggacga tttggcggag ccaaggtatc aggtctataa tcgtcagacc atgccaggtg
     6181 gtcagggcta tcttatgtat agcaatgctt catccagtat tcgagcagtg ggcaatatct
     6241 ttcctgtggt actttatgcc gtagcagcca tggtgacctt tacgaccatg actcgctttg
     6301 tagacgaaga gcgaactcat gcagggattt ttaaggcctt gggttatcgt agtaaggata
     6361 ttatcgccaa gtttctcctt tatggactag tagctgggac tgtcggaacg gctctaggta
     6421 gtatacttgg tcattatttg ctagccaatg taatttcaag tgtcattaca aaaggcatgg
     6481 tggtgggaga aactcagatt cagttctatt ggacctatag cttactagct cttgtcttga
     6541 gcttgttggc gagtgtgtta ccagcctatc tggtggcttg gagggaactt catgacgaag
     6601 cagcccagct tctacttcct aaacctcctg tcaaaggagc taaaatatta ttggagcgta
     6661 tcggttttat ctggcgtcgt ctcagtttta ctcataaggt aacagcccgc aacatctttc
     6721 gttataagca gagaatgttg atgacaatct ttggtgtggc aggttctgta gctctgctct
     6781 ttgcaggttt gggaatccaa tcttctgtag caggagttcc gtctaaacag tttcaacaaa
     6841 tccaacagta tcagatgctt gtctctgaaa atcctagtgc gaccaatcag gacaaggtag
     6901 agctagcaga agtgttgaaa gggcaggaga tactagccta ccagaaaatc tattctaaaa
     6961 cgctagacaa ggatttcaaa ggcaaggctg gtcttcaaaa cattactctt atgatgatag
     7021 agaaggaaga tttgactccc tttatccatc ttcaacatca tcagcaggag ctgacattaa
     7081 aagatggcat cgttattaca gctaaactcg cccagctggc aggtgtcaag gttgggcaga
     7141 ctttagaaat tgaaggtaag gaactaaagg tcgctgctat tactgagaac tacgttggtc
     7201 actttattta tatgagtcag gctagctatg agcaacttta cggacagcta ccccaagcca
     7261 acacttatct ggtctcatta agggatacca gtgcaactag tatcgaaagt caggcgggct
     7321 tgcttatgaa tcaatctgcg gtgtccagcg ttgtccaaaa tgcttcagcc attcgactct
     7381 tcgactctat cgctagctca ctcaatcaga ccatgaccat cttggtcatc gtatcggttc
     7441 tattagctat tgtcatcctt tacaatctga ccaatatcaa cgtagctgag agaatccgtg
     7501 aactctccac tatcaaggtt ctcggttttc ataataatga agtcaccctc tacatttatc
     7561 gtgagacgat tgtgctgtcc cttgtgggaa tcgtacttgg tctggtagct ggtttctatt
     7621 tacaccaatt tttgattcaa atgatttcgc ctgcgactat tctcttttat ccgcagatag
     7681 gctgggaagt ctatgtaatc ccagtggcag cagtaagcat cattttgacc ttgcttggtt
     7741 tcttcgtcaa ttattatctg agaaaggttg atatgttaga agccctgaaa tctgtagagt
     7801 aaggtagtta tttttagctg attgaacttc tatttactaa tattcaaaaa tcctccgttt
     7861 caaagagcag ggaactcttt gtgacagagg attttttcta tagggcttta gcagctgcaa
     7921 ttgcggcttc gaagtttggc tcagaattga tattatccac gtattcaacg tagcgaatcg
     7981 tattgtcagt atcgaggaca aagactgcgc gtgctaatag gtgccattcg ttgatcaaga
     8041 gggcataatc gcgcccgaaa gaatggtcaa agtagtctga aagcataatg gcattgtcaa
     8101 ggccttcagc accgcaccaa cgtttttgag caaaaggtag gtccattgaa acagtcaata
     8161 cgaccgtgtt gtccagtcca gccaattctt cattaaaacg acgtgtttga gttgagcaga
     8221 tgcctgtatc gatagaagga acgacactca agactttttt cttgccatca aaatcagcca
     8281 gagatttttt agaaagatct gttgtagtaa gagaaaaatc aagcgccttg tcgccgactt
     8341 gtagttgttt acctgtaaag ctcacaggat ttccgagaaa agttaccata ggatactcca
     8401 atcttttttc ttccattgta tctgaaacag tcagaatttt ccaatgattt gaccggaaat
     8461 gtgggcatag aaaaaacgcc agctcacatg agaatgacgt ttttcagagg cttattttgc
     8521 caatccttca gcaatcttgt caaggttgta tttcatcatg ctgtagtagc tgtcgccttc
     8581 tttaccttgt tctgcgatag agtcagtaaa gatttgtgcg tagattggga tgtttgtgtc
     8641 ttgagaaaca gttttcattg gacggtcatc cacacttgat tctacaaaga gtgatggaac
     8701 ttttgtttgg cgaagttttt caaccaaggt cttgatttgt tcaggagttc cttcttcttc
     8761 agtattgatt tcccagatgt aggcacttgg gacaccatag gctttagaga agtatttgaa
     8821 tgctccttcg ctggttacaa tgagtttctt ttcagcaggg atcttattaa atttatcctt
     8881 actttcttta tcaagtttgt ctaacttatc agtatattct ttgagatttt tttcatagaa
     8941 ttctttattg ttagggtctt tggcgctcaa ttgtttggcg atatttttag caaaaataat
     9001 accgttttca aggttaagcc aagcgtgtgg gtcttctttt cctttttcat tttgaccttc
     9061 aaggtagata acatcaacgc cgtcgctgac tgcgaagtag tctttgtttt cagttttctt
     9121 ggcattttct accaattttg taaaccaagc attgccacct gtttcaaggt tgataccgtt
     9181 atagaaaatc aaatcagcct cagaagtttt cttaacgtct tcaggaagtg gttcgtattc
     9241 gtgtgggtct tgcccaatcg gaacgatact atgaaggtca attttgtcac cagcaatatt
     9301 tttagtaata tcagcgatga ttgagtttgt agcaacaact tttagttttt gaccagaagt
     9361 tgtatctttt tttccgctag cacatgctac aagaatgatt gcagaaagaa agagaacgag
     9421 taatgtacct aattttttca ttagatcctc caatttatta gggctttgcc ccttatttta
     9481 acaaatgttt atttttcagt ttcaaatatc gttgtttggg agcgataaag aagctaatga
     9541 gaaagaaact agcagctgta agcacgatac tagaacctgc cgcaacatta aaactatagc
     9601 caataaagag tcccaaaact gaagcagtag ctccgaaggt tgaggaaagg aaaatcatgc
     9661 ttttcagact attagcatac agataagcag ttgcagctgg ggtaatcagc atggctacaa
     9721 tcaggatagt tccgacactt tgcatggctg tcacagacac gagagtcagg agtaccatga
     9781 gaaggtagtg atagaaattg acaggcattc ccatggcttt agccaagagt tcatcaaagg
     9841 aagttatcaa gagttgcttg aagaaaatcc agattaacaa gaggatggct gcccccacac
     9901 ccatagtaat aaacatatcc gtatcttgga cggccaggat attaccaaaa aggatatgga
     9961 aaaggtcagt tgaactttta gcgacaccaa tcaagatgat accgagggct aagaaagaag
    10021 aaaaggtaat gccgatggcg gtatcgcttt tgataatcga gtttcctttg atgtaggtaa
    10081 tgatgatggc agctagcaat ccaaagacaa tggctccgat aaagaagtca aggcccaaga
    10141 tgaaggagag ggctacacct ggtaagacag catgtgaaat ggcatctccc atgagtgaca
    10201 tcccgcgtag aataatgaaa catcccacag ctccagctac aatcccgacg acaatagctg
    10261 ttatcaaggc attttgtagg aaatggaatt tttgcaatcc atcgataaat tctgcaatca
    10321 taggtcacct ccattgaaaa agagttgatt accgtaagct tcttttagat tggtttcggt
    10381 aaaagtttct tttgttggac caaaggcaat cacttctcga ttgacaagta agacttgatc
    10441 gaagtagtgg ggaatcttgc tgaggtcgtg gtgaacgatg agaaccgtct tcccagcttt
    10501 tttcaaatct ctcagcgtat tcatgatgat ttcctcactg acagagtcaa tcccagcaaa
    10561 gggttcatcc aagaggatat agtcggcttc ctgcaccaaa catctggcaa tcaaaacccg
    10621 ctggaattga cctccagaca gttgactaat ttgacgttca gcgtagtcag ctaggccgac
    10681 gatttcaagg gcctcttgca ctttcttcca atgtttagtc tttaaacttc gaaagagagg
    10741 aatagaggga aatagtccta acgagacgca ttccttgacc ttgatgggaa agttgtagtc
    10801 gatattgatt ttttgttcga cataggcaat tcggtgtaag gattttttaa cttccttgtc
    10861 atcgagaaat gcctgacctt gatgtgggat aattcccagc atacctttta atagtgttga
    10921 tttcccagcg ccgtttggac caatgatgcc ggtaattgtt ggtccatgga gcactagtga
    10981 aatatcctta agtgccaacg tttctttgta ggagacactg aggttttcga tacgtatcat
    11041 aaacttgtat tcctcctgtc tcttaatata cattaaaaaa aaaattaagt caagttaatt
    11101 tttgaaaaaa ttaaaataat aactgaaaaa tagattctaa agataacttt caggataaat
    11161 tt
//
LOCUS       DAVKAU010000057        11015 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVKAU010000057 DAVKAU010000000
VERSION     DAVKAU010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11015
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.057"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            191..1397
                     /locus_tag="VWX48_001758"
                     /pseudo
     CDS             191..1397
                     /locus_tag="VWX48_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            1399..2129
                     /locus_tag="VWX48_001759"
                     /pseudo
     CDS             1399..2129
                     /locus_tag="VWX48_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
     gene            2138..2830
                     /gene="cpsC"
                     /locus_tag="VWX48_001760"
     CDS             2138..2830
                     /gene="cpsC"
                     /locus_tag="VWX48_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU9172340.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVA
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLGKLK"
     gene            2840..3257
                     /locus_tag="VWX48_001761"
                     /pseudo
     CDS             2840..3257
                     /locus_tag="VWX48_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
     gene            complement(3326..3781)
                     /locus_tag="VWX48_001762"
                     /pseudo
     CDS             complement(3326..3781)
                     /locus_tag="VWX48_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
     gene            3805..4221
                     /locus_tag="VWX48_001763"
                     /pseudo
     CDS             3805..4221
                     /locus_tag="VWX48_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
     gene            4399..5583
                     /locus_tag="VWX48_001764"
     CDS             4399..5583
                     /locus_tag="VWX48_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU9172341.1"
                     /translation="MKIAIAGSGYVGLSLAVLLAQHHEVKVIDVIKDKVESINNRKSP
                     IKDEAIEKYLVEKELNLEASLDPAHVYKDVEYAIIATPTNYDVDLNQFDTSSVEAAIK
                     TCMEYNDTCTIVIKSTIPEGYTKEVREKFNTDRIIFSPEFLRESKALYDNLYPSRIVV
                     GTDLDDSELTKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVAYFN
                     EIDTYSEVKGLNPKTIIDIVCYDPRIGSYYNNPSFGYGGYCLPKDTKQLKASFRDVPE
                     NLITAVVQSNKTRKDYIAGAILAKQPSVVGIYRLIMKSDSDNFRSSAVKGVMERLDNY
                     GKEIVIYEPTIECDTFMGYRVIKSLDEFKNISDIVVANRMHDDLRDIQEKLYTRDLFG
                     RE"
     gene            5599..6852
                     /locus_tag="VWX48_001765"
     CDS             5599..6852
                     /locus_tag="VWX48_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9172342.1"
                     /translation="MYTFILMLLDFFQNHDFHFFMLFFVFILIRWAVIYFHAVRYKSY
                     SCSVSDEKLFSSVIIPVVDEPLNLFESVLNRISRHKPSEIIVVINGPKNERLVKLCHD
                     FNEKLENNMTPIQCYYTPVPGKRNAIRVGLEHVDSQSDITVLVDSDTVWTPRTLSELL
                     KPFVCDKKIGGVTTRQKILDPERNLVTMFANLLEEIRAEGTMKAMSVTGKVGCLPGRT
                     IAFRTEILRECIHEFMNETFMGFHKEVSDDRSLTNLTLKKGYKTVMQDTSVVYTDAPT
                     SWKKFIRQQLRWAEGSQYNNLKMTPWMIRNAPLMFFIYFTDMILPMLLISFGVNIFLL
                     KILNITTIVYTASWWEIILYVLLGMIFSFGGRNFKAMSRMKWYYVFLIPVFIIVLSII
                     MCPIRLLGLMRCSDDLGWGTRNLTE"
     gene            7150..8070
                     /gene="galU"
                     /locus_tag="VWX48_001766"
     CDS             7150..8070
                     /gene="galU"
                     /locus_tag="VWX48_001766"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU9172343.1"
                     /translation="MKKVKKAVIPAAGLGTRFLPATKALAKEMLPIVDRPTIHFVIEE
                     ALRSGIEDILVVTGKSKRSIEDYFDSTFELEYSLRKQGKMELLKSVNESTDIKVHFVR
                     QSSPRGLGDAVLQAKSFVGDDPFVVMLGDDLMDITDSTAVPLTRQLMDDYNATQASTI
                     AVMPVRYEDVSSYGVISPRLESSNGLYSVDAFVEKPKPEEAPSNLAIIGRYLLTPEIF
                     SILETQKPGAGNEIQLTDAIDTLNKTQSVFAREFVGKRYDVGDKFNFMKTSIDYALQH
                     PQIKESLKNYVIALGKQLEKLDDCSSSGHL"
     gene            8067..9284
                     /locus_tag="VWX48_001767"
     CDS             8067..9284
                     /locus_tag="VWX48_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU9172344.1"
                     /translation="MNCIESYQKWLNVPDLPAYLKDELLSMDDKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLVESKGETAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMLPADADALTDYIRAIDNPFAVALADLEEAKSTGLIEVIGETLDSAYLEEVKSVNI
                     NQDLIDQYGRDMKIVYTPLHGTGEMLARRALAQAGFESVQVVEAQAKPAPDFSTVASP
                     NPESQAAFALAEELGRQVDADVLVATDPDADRLGVEIRQADGSYWNLSGNQIGALIAK
                     YILEAHKQAGTLPKNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEEG"
     gene            complement(9211..9768)
                     /locus_tag="VWX48_001768"
     CDS             complement(9211..9768)
                     /locus_tag="VWX48_001768"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9172345.1"
                     /translation="MIKCLFPNAQIVLDRFHIIQHLSREMMTTRIVIMKNFDKQSLPY
                     RAMKNHWRIFQKDSRKLSDKAFYSRTFRQTLTPREIVNKTLAFSDELHYYDDLYQLLL
                     FHLQEKNADHFFDLLTEAFPQLNQAFRTALSTLVRYRKYVTNTIQMPYSNSKLEAINK
                     LISLLQTQTCRYGYVFLQILEFSQR"
     gene            9768..10856
                     /locus_tag="VWX48_001769"
                     /pseudo
     CDS             9768..10856
                     /locus_tag="VWX48_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein"
BASE COUNT         3533 a         1729 c         2328 g         3425 t
ORIGIN      
        1 ggtcttgttc ataattagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
       61 agaaatcgat ttgactgtcc tgatcgattt gtcctgttct tatttcattt tactatattt
      121 ttggttcgcg ggaagtctac taagatactt aaagatacag atagtgaaaa taaaggtgta
      181 gacattaccg ttggtgttct ctatccttgt cagctctgtg tcgctctttg cagtacagca
      241 gtttgttgga ctgaccaatc gtttaaatgc gacttctaat tactcagaat attcgatcag
      301 tgtcgctgtt ttagcagata gtgagatcga aaatgttatg caactgacga gtgtgacagc
      361 accgactggg actgataatg aaaatattca aaaattacta gctgatatca agtcagaata
      421 ccgatttgac ggtcgaccag agttcgtctt acttggctgc ttacaagagt ctgattgcag
      481 gtgacaccaa gaccattgtc ctaaatagtg tctttgaaaa tatcatcgag tcagagtatc
      541 cagactacgc atcgaagata aaaaatattt ataccaaggg atttactaaa aaagtagaag
      601 ctcctaagac gtctaagaat cagtctttca atatctaagt tagtggaatt gacacctatg
      661 gtcctattag ttcggtgtcg cgatcagatg tcaatatcct gatgactgtc aatcgagata
      721 ccaagaaaat cctcttgacc acaacgccgc gtgatgccta tgtaccaatt gcagatggtg
      781 gaaataatca aaaagataaa ttgactcatg cgggcattta tggagttgat tcgtccattc
      841 acaccttaga aaatctctat ggagtggata tcaattacta tgtacgattg aacttcactt
      901 cgtttttgaa attgattgat ttgttggatg gaattgatgt ttataatgat caagaattta
      961 ctgcccatac gaatggaaag tattaccctg aaggcaatgt tcatcttgat tcagaacagg
     1021 ctctcggttt tgttcgtgag cgctactccc tagcagatgg cgatcgtgac cgcgggcgca
     1081 atcaacaaaa ggtgattgtg gctatccttc aaaaattaac gtcaaccgaa gaactgaaaa
     1141 attatagtac gatcattgat agcttgcaag attctatcca aacaaatatg ccgattgaga
     1201 ctatgataga tttagtgaat actcagttgg aaagtggagg gaattataaa gtaaattctc
     1261 aagatttaaa agggacaggt cggatggatc ttccttctta tgcaatgcca gacagtaacc
     1321 tctatgtgat ggaaatagat gatagtagtt tagctgtagt taaagcagct atacaggatg
     1381 tgatgaaagg tagatgaaat gatagacatc cattcgcata tcgtttttga tgtagatgac
     1441 ggtcccaagt caatagagga tagcaaggca cttttaagag aagcttataa tcaaggagtt
     1501 cgaatgattg tgtctacttc gcatcgtcga aaagggatgt ttgaaactcc agaagaaaaa
     1561 attgtaacaa attttattaa ggttcgtgaa attgcaaaag aagtagcaga tgatttagtc
     1621 attgcttatg gcgcagagat atactatact ctggatgctc tagaaaagct agaaaaaaag
     1681 aaattcctac ccttaatgat agtcgttatg ctttgattga gtttagcatg catacttcct
     1741 atcgtgagat tcatacgaga ttgagcaata ttttgatgtt gggaatcacg ccagtaattg
     1801 ctcatattga acgttatgat gctttagaga ataacgaaaa acgtgttcgt gaactgattg
     1861 atatggggtg ctatactcag atagatagtt atcatgtttc aaaacctaag ttctttggtg
     1921 aaaaatataa attcatgaaa aagagagctc ggtatttttt ggaacgtgat ttagttcatg
     1981 tagttgcaag tgacatgcac aatttagaca gtagacctcc atatatgcaa caggcatatg
     2041 atatcattgc taagaaatat agagcgaaaa aagcgaaaga actttttgta gataatccca
     2101 gaaaaattat aatggatcaa ttaatttagg agaaaatatg aaggaacaaa acactttgga
     2161 aatcgatgta ttgcaactat tcagagcttt atggaaaaga aagttggtca ttttattagt
     2221 ggcaattata acttcttcag ttgcttttgc ctacagtact tttgttatca aacctgagtt
     2281 tactagtacg actcggattt atgtagttaa ccgtaatcag ggagagaagt ctggtttaac
     2341 caatcaagac ttgcaggcag gatcatactt ggttaaagac tatcgtgaaa ttatcctatc
     2401 gcaggatgtt ttggaggaag ttatttctga tttgaaacta gatttgacgc caaaaggttt
     2461 ggctaataaa attaaagtaa cagtaccagt tgatacccgt attgtctctg tttcagttaa
     2521 tgatcgagtt cctgaagagg caagccgtat cgctaactct ttgagagaag tagctgctca
     2581 aaaaattatc agtattactc gtgtttctga tgtggcaaca ctggaggagg caagaccggc
     2641 gatatcaccg tcttcgccaa atattaaacg caatacacta attggttttt tggcaggggg
     2701 gattggaact agtgttatag ttcttcttct tgaacttttg gacactcatg tgaaacgtcc
     2761 ggaagatatc gaagatacac tgcagatgac acttttggga gttgtaccaa acttgggtaa
     2821 gttgaaatag gagagaggaa tgccgacatt agaaatagca caaaaaactg gagttcatta
     2881 agaaggcaga agaatattac aatgccttgt gtacaaatat acagttgagc ggagataaac
     2941 taaaagtaat ttccgttact tctgttaacc ctggggaagg aaaaacaact acttccgtaa
     3001 atatagcaag gtcgtttgcg cgtgcaggct ataaaactct tttgatcgat ggtgatactc
     3061 gaaattcagt tatgtcagga ttttttaaat ctcgtgaaaa aattacagag ctaacagaat
     3121 ttttatctgg gatagctgat ttatctcacg gtttatgtga tacaaatatt gaaaatttat
     3181 ttgtagttca atcgggatct gtatcaccaa accctacagc cttgttacaa agtaaaaatt
     3241 ttgtggttat ggtaaagatt ttttcaaaag aggtcagtat attgagttgg tggaaacgat
     3301 aaaatacata atattttatt cctttggtta tcaaattagc ccctcctgaa gctccccaat
     3361 tgacggcttg agctccaatc aaagggtgtt tgtccgcttt ttgacagagg gtaatcgcta
     3421 gaggacagca aacggccata gtagtgaaaa atccagcacc taaagcagac aaaagggttg
     3481 ccatcaggta taaaatcatg tagagggcgt tagggtgggt gcgtgtgcgg tagagaatgt
     3541 gttgagccaa aacatcaaga gtaccgttag ttgttgcaac gttataaaag agagagacgc
     3601 taaaaatggt aaaaaagagt gaggttggcc aaaaatgaag aagttttttg ggacttaatc
     3661 ccatgagagt ggttgcgatg aggtaagaaa aagcaatagc cagcaggcca atattgattt
     3721 tggtgcggta accaattcca atggctagag caatggcgct aatcattatt aaatgaatca
     3781 ttgaattgtc ctttcagtta gaatatagaa agaggataga ttgaagttcg agaatactgg
     3841 gtgtcttctg atgttaagtg gttgtgtcaa aaccatccca aatggcataa attgcgtgga
     3901 attggaatga ctcgtaatac tattgataga gatggtatta caagtcaaga cgttcgctat
     3961 tttatcttta actttaagct tgatgtgatg accttttgcc atagtgttcg aggtcattgg
     4021 tcagcagaaa gtatgcattg gttattggat gtggtttatc gtgaagacca tcatcagacc
     4081 ctggataaac gagctgcttt taaccttaat cttatccgaa aaatgtgttt atattttcta
     4141 aaagtgatgg tattttctaa aaaagacctc agctatcgat gcaaacaacg gtatatctct
     4201 gtccatttgg aagattattt ggaaacagag gttaggaaag taattagttt aacgggatat
     4261 cttttcaaag ctgatactaa ggcacaaaaa aagtttgata ttccccttga caatagataa
     4321 aattattata taattaaatt attgcttttt aaataaagtg agaatattaa taatacagag
     4381 aaagaggact gtagtaaaat gaaaattgcc attgcaggaa gtggttatgt aggactgtct
     4441 ttagcggtgc tactagctca gcatcatgaa gttaaggtca ttgatgttat aaaggataag
     4501 gtagagtcga taaacaatag aaaatctcca attaaggatg aggcgattga gaaatactta
     4561 gttgaaaaag agttgaatct tgaagcctcc ttagatcctg cacacgttta taaagacgtg
     4621 gagtatgcta ttattgctac tccgactaat tatgatgtag acttaaatca gtttgataca
     4681 tcttcagttg aagctgctat caagacttgt atggaatata atgatacttg tacaatcgta
     4741 atcaaaagta ctattcctga agggtatact aaagaagtga gggaaaagtt taatacagat
     4801 cgtattattt tttctccaga gtttctacgt gaatccaaag ctttatatga taatttgtat
     4861 ccatctagaa ttgttgtagg aactgatttg gatgattctg agttaacaaa aagagcatgg
     4921 cagtttgcag atctacttaa aggtggagct attaaggaag aggttccgat actggttgtt
     4981 gcttttaatg aagcagaggt tgcaaaattg tttagtaaca cttacttggc aactcgcgta
     5041 gcttatttta atgagataga tacatatagc gaggtaaaag ggcttaatcc caagacaatt
     5101 attgatattg tttgttatga tcctagaatt ggatcatact ataataaccc tagctttggt
     5161 tacggagggt attgcttacc aaaagacaca aagcaattga aagcaagttt tagggatgtt
     5221 cctgaaaatc tgattacagc tgtggtgcaa tctaataaaa caagaaaaga ttatatagct
     5281 ggagctattc tagctaaaca acctagtgtt gtaggtattt atagattaat tatgaaatct
     5341 gattctgata attttcgttc tagtgctgtt aagggagtta tggaacgttt ggacaattat
     5401 ggtaaagaaa ttgttattta cgaacctact attgagtgtg atacttttat gggatacaga
     5461 gtaattaaat ctttagatga atttaagaat atttctgaca ttgttgtagc gaatcgtatg
     5521 cacgatgatt taagggatat acaagaaaaa ctctatacac gcgatttatt tggcagagaa
     5581 taaggggcaa taatttttat gtatacattt attttaatgt tattggattt ttttcagaat
     5641 catgattttc atttctttat gttgtttttt gtctttattc ttattcgttg ggcggttata
     5701 tattttcatg ctgtcagata taagtcctac agttgtagtg taagtgatga gaagttattt
     5761 agttctgtaa ttatccctgt cgtggatgaa ccacttaatc tttttgaaag tgtactgaat
     5821 agaatttcca gacataaacc atccgaaatt attgtggtta ttaacggccc aaaaaacgag
     5881 agacttgtaa aactttgtca tgattttaat gaaaaattag aaaataatat gactccaatt
     5941 caatgttatt acactcctgt tcctggcaag agaaatgcta tccgcgttgg gctggagcat
     6001 gtggattcgc agagtgatat tacagttcta gtagatagtg atacagtatg gacgcctaga
     6061 accttgagtg agttgctgaa gccttttgtt tgcgataaaa aaataggtgg ggtaacgaca
     6121 agacaaaaaa ttcttgaccc tgagcgtaat ctcgtgacaa tgtttgctaa cttgttagag
     6181 gaaattaggg cagaaggaac tatgaaagca atgagtgtga ctggtaaagt agggtgctta
     6241 cctggtcgaa caattgcttt tagaacagag attctcagag agtgtataca tgagtttatg
     6301 aatgaaactt tcatgggatt tcataaggaa gtttctgatg atagaagtct tacaaatttg
     6361 actttaaaaa aaggctataa aactgttatg caggatactt ctgttgtgta tacagatgct
     6421 cctacaagtt ggaaaaagtt cattagacag caactaaggt gggcagaagg ttctcagtat
     6481 aacaatctaa agatgactcc ttggatgatt agaaatgccc ctcttatgtt ttttatttat
     6541 tttacagata tgattttacc tatgctactt attagctttg gtgtgaatat attcctgttg
     6601 aaaatattaa atataactac aattgtttat acagcttcat ggtgggaaat tattttatat
     6661 gttcttttgg gaatgatttt tagctttgga ggaagaaact ttaaagctat gtctagaatg
     6721 aagtggtatt atgtatttct tattcctgtt tttataatcg ttttgagtat aattatgtgc
     6781 cctattaggc tattaggact tatgagatgt tctgatgatt tagggtgggg aactaggaat
     6841 ttaacagagt gagataaata gtagtgcgta tatagagtat ttactcagag tattaattga
     6901 tttttgaaaa ggaaaagtgt tttttaatgt taagaaagaa cttgaaatat cagattatga
     6961 cacgagctgg aacaatttta gctatcttgt ttttcattat attagggatt attgttgaag
     7021 ttttgtttta aggctcattg tcatctgtag tggctcactt cagacgtaag ggtcatattt
     7081 taatgtgaaa agagtgttaa aagattaatc acttatatta ttttaataga aatagtgtaa
     7141 ggaattgtta tgaaaaaagt aaaaaaagct gttattcctg ctgcagggct gggcacacga
     7201 tttttgcctg ccactaaagc tttggcaaaa gaaatgcttc caattgtaga ccgccccaca
     7261 attcattttg tcattgaaga agctttacgt tcgggtattg aagatattct agtagttact
     7321 ggaaagagta aacgttctat tgaagattat tttgattcaa cttttgaatt ggaatatagt
     7381 cttagaaaac aaggaaagat ggaacttctt aagtcagtta atgaatcgac tgatattaaa
     7441 gtacatttcg ttcgtcaaag ttcaccacgt ggtcttggtg acgctgttct ccaagcgaag
     7501 tcttttgttg gtgacgatcc ctttgttgta atgcttggtg atgaccttat ggatatcacc
     7561 gactcaactg ctgtaccttt aacaagacaa ttgatggatg attacaacgc aacacaggct
     7621 tcaactatcg cagtaatgcc tgttagatat gaagatgttt cttcttatgg tgtgatttct
     7681 cctagattgg aaagtagtaa tggcctctat agtgttgatg cttttgtaga gaaaccaaaa
     7741 ccagaagaag cgcctagcaa tttagctatt attggacgtt atctacttac tcctgagatt
     7801 ttttctatat tagaaaccca aaagccagga gcaggtaatg aaattcaatt gacagatgct
     7861 attgatacat tgaataagac acagagtgtt tttgcgcgtg aatttgtggg caaacgttat
     7921 gatgttggtg ataagtttaa ttttatgaaa acatcaattg attatgctct tcaacatcct
     7981 cagattaaag agagtttaaa aaattacgtt attgcacttg gtaagcaatt ggagaagcta
     8041 gatgactgtt cgtcaagtgg acacctatga attgtataga aagttatcaa aaatggctaa
     8101 atgtccctga tcttccagct tatttaaaag atgaattgct cagcatggat gacaaaacaa
     8161 aagaagacgc cttttacaca aaccttgaat tcggaacagc tggtatgcgt ggttatattg
     8221 gtgctgggac aaaccgtatt aatatctatg tggtgcgtca agcaacagaa ggccttgcca
     8281 aattagttga atcaaaaggc gaaacggcca aaaaagctgg ggttgctatt gcctatgact
     8341 cgcgacattt ttcaccagaa ttcgcttttg aatctgccca agtattagcg gcccatggca
     8401 ttaaatctta tgtttttgaa agcctacgcc ctactcctga gctgtctttt gctgttcgtc
     8461 atctcggagc atttgctggt attatggtaa ccgccagtca taaccctgct ccttttaatg
     8521 gttataaagt ttacggttct gatggtgggc aaatgcttcc agctgatgct gatgctttaa
     8581 ctgactatat tcgtgcgatt gataacccat ttgctgtagc ccttgctgac ttagaagaag
     8641 ctaaatcaac tggtcttatt gaagtaattg gtgaaactct cgattctgcc taccttgaag
     8701 aggttaaaag cgttaatatc aatcaagatt tgattgacca atacggtcgc gatatgaaaa
     8761 ttgtctacac acctcttcat ggtactggag aaatgttagc acgtcgagct ttagcacaag
     8821 ctggtttcga atctgttcaa gttgtcgaag ctcaagcaaa accagcccca gacttctcaa
     8881 cagttgcatc accaaaccct gaaagtcaag ccgcctttgc cttagctgaa gaactagggc
     8941 gtcaagtcga tgctgatgta ttagtggcga ctgaccctga tgctgaccgt ctcggtgttg
     9001 aaattcgtca agctgatggc agttattgga acctttctgg taaccaaatc ggtgctctta
     9061 tcgccaaata cattttagaa gctcacaaac aagctgggac actcccaaag aatgctgcat
     9121 tggcaaaatc aatagtatca actgaattag tcaccaaaat tgcggaaagc tatggtgcaa
     9181 ccatgtttaa cgtgttaaca ggtttcaaat tcatcgctga gaaaattcaa gaatttgaag
     9241 aaaaacataa ccatacctac atgtttgggt ttgaagaagg ctgatgagtt tattgattgc
     9301 ctccagcttg gagttagaat agggcatctg gatggtattt gtcacgtatt ttctgtagcg
     9361 aaccagcgtg ctaagagcag ttctaaaggc ttgattgagt tggggaaaag cctcagttaa
     9421 caagtcaaag aaatggtcgg cattcttttc ttgcaggtgg aaaagcagga gctggtaaag
     9481 atcgtcataa tagtggagct catctgagaa agctaaggtt ttattgacga tttctcgagg
     9541 tgtcagtgtc tgtctaaaag ttcttgagta gaaggcctta tcagacagtt ttcggctatc
     9601 tttttggaaa attcgccagt gatttttcat ggcgcgatag ggaagtgatt gcttgtcaaa
     9661 attcttcatg atgacaattc tggttgtcat catctcacgg cttaggtgct ggatgatatg
     9721 aaatctatca aggacgattt gtgcatttgg aaataggcat ttaatcacaa gactctatta
     9781 cgtatctagt tggtacaaat attgaccgtc agtcctataa atatacatct aagaccagtg
     9841 aagaacaaaa aacatctacg aaaaaggctc tcttaaacaa ggatttccgt caggctattg
     9901 catttggatt tgaccgtaca gcctatgcct ctcagttgaa tggacaaact ggagcaagca
     9961 aaatcttacg taatctcttt gttccaccaa catttgttca agcagatggt aaaaactttg
    10021 gcgatatggt caaagagaaa ttggtcactt atggggatga atggaaggat gttaatcttg
    10081 cagattctca ggatggtctt tacaatccag aaaaagccaa ggctgaattt gctaaagcta
    10141 aattagcctt acaagcagaa ggagtccaat tcccaattca tttagatatg ccagttgacc
    10201 agacagcaac tacaaaagtt cagcgcgtcc aatctatgaa acaatccttg gaagcaactt
    10261 taggaactga taatgtcatt attgatatcc aacaactaca aaaagacgaa gtaaacgata
    10321 ttacatattt tgctgaaaac gctgctggcg aagactggga tttatcagat aatgtcggtt
    10381 ggggtccaga ctttgccgat ccatcaacct accttgatat catcaaacca tctgtaggag
    10441 aaagtactaa aacatattta gggtttgact caggggaaga taatgtagct gctaaaaaag
    10501 taggtctata tgactacgaa aaattggtta ctgaggctgg tgatgaggct acagatgttg
    10561 ctaaacgcta tgataaatac gctgcagccc aagcttggtt gacagatagt gctttgatta
    10621 ttccaactac atctcgtaca gggcgtccaa tcttgtctaa gatggtacca tttacaatac
    10681 catttgcatt gtcaggaaat aaaggtacaa gtgaaccaat cttatataaa tacttggaac
    10741 ttcaagacaa ggcagtcact gtagatgaat accaaaaagc tcaggaaaaa tggatgaaag
    10801 aaaaagaaga gtctaataaa aaggctcaag aagatctcgc aaaacatgtg aaataactgt
    10861 tgcaaaatat aagaaaggat ttagtatttc ccttgaatgc tgaatccttt tttacatttg
    10921 taaagaaaga ttctaaatgt acggaccccc aaaagttgga gtctcttttt gtcagaatag
    10981 agaaaatttt tgttaatttt acttgtttcc tattg
//
LOCUS       DAVKAU010000058        10996 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVKAU010000058 DAVKAU010000000
VERSION     DAVKAU010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.058"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..385)
                     /locus_tag="VWX48_001770"
     CDS             complement(<1..385)
                     /locus_tag="VWX48_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU9172346.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFL"
     gene            complement(432..686)
                     /locus_tag="VWX48_001771"
     CDS             complement(432..686)
                     /locus_tag="VWX48_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU9172347.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQINVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            complement(688..930)
                     /locus_tag="VWX48_001772"
     CDS             complement(688..930)
                     /locus_tag="VWX48_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU9172348.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            complement(1021..1830)
                     /locus_tag="VWX48_001773"
     CDS             complement(1021..1830)
                     /locus_tag="VWX48_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9172349.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            complement(1832..3181)
                     /gene="vicK"
                     /locus_tag="VWX48_001774"
     CDS             complement(1832..3181)
                     /gene="vicK"
                     /locus_tag="VWX48_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU9172350.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            complement(3174..3878)
                     /locus_tag="VWX48_001775"
     CDS             complement(3174..3878)
                     /locus_tag="VWX48_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9172351.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            complement(3933..5108)
                     /gene="mutY"
                     /locus_tag="VWX48_001776"
     CDS             complement(3933..5108)
                     /gene="mutY"
                     /locus_tag="VWX48_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU9172352.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            complement(5437..7107)
                     /locus_tag="VWX48_001777"
     CDS             complement(5437..7107)
                     /locus_tag="VWX48_001777"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU9172353.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            7337..8026
                     /gene="coaB"
                     /locus_tag="VWX48_001778"
     CDS             7337..8026
                     /gene="coaB"
                     /locus_tag="VWX48_001778"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU9172354.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISTDQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            8038..8589
                     /gene="coaC"
                     /locus_tag="VWX48_001779"
     CDS             8038..8589
                     /gene="coaC"
                     /locus_tag="VWX48_001779"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU9172355.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLITPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            8573..9136
                     /locus_tag="VWX48_001780"
     CDS             8573..9136
                     /locus_tag="VWX48_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9172356.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            9418..9945
                     /locus_tag="VWX48_001781"
     CDS             9418..9945
                     /locus_tag="VWX48_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9172357.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            9957..10472
                     /locus_tag="VWX48_001782"
     CDS             9957..10472
                     /locus_tag="VWX48_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU9172358.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(10469..10936)
                     /locus_tag="VWX48_001783"
     CDS             complement(10469..10936)
                     /locus_tag="VWX48_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9172359.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
BASE COUNT         3277 a         2441 c         1932 g         3346 t
ORIGIN      
        1 gtaagaatct actaattttt ctttctaatt tacctgtaag tccaattatt ctaagtaaac
       61 gagtcagttt cagtaatttt gttagtttaa ctaaacgaaa gatacgccct aatcgaaaaa
      121 ctgtgaaaat agcatttaaa gggagaatag ccaataaatc aaaaatattt tcaagaataa
      181 agcgccattt tcttttagta ataaaaaagc gccaactata atcaattaca aaaacacccc
      241 agattactaa atcaataata ctataaggcg gattgtccaa atcaatcatc tcagcaaatc
      301 caagtaatac cagaataaca gagattaaag caagtaaaat aattgttgta tcataataat
      361 ctgcaaaaaa ccattttttc ttcaaatttt tactctcctt actttctata ttgttattac
      421 tcagctttaa ttcaataaat atctctccga tgaccaactt ctagagtagc aacaactaat
      481 tcatcatcta caatttgtac gataactcga taattaccaa ttctatagcg ccattgacca
      541 acgcgattac caaccaaagc ctttccgtgt cgtcttgggt cttccaaaac attgatttgt
      601 aaatagtttg taattagctt ctgcgtataa cggtccaatt ttttcaattg cttgatgaaa
      661 cgtcttgttg gaactaattt atacaaatta ttcatccttc aagcctaaat catgcatcat
      721 ttcttcccaa gtaatgggtt caactccttt ttccaagtct tctaaatact cttgataggc
      781 taaatctgcc acacgagcat cgtattcatc ttctagggct tcaagagttt tggtgcgaat
      841 aagttccgaa agggaaactc cttcaaactt agccattgct ttcataaatg ttttatcagc
      901 ttcagaaact tttaatgtaa tagtagtcat cttttgtgct ccctttttta atggtaacac
      961 cattgtatta ctttttaggt gttcagtcaa tataaaaaga acaccttctc agcgttcttt
     1021 ctatatctct gtcaatggtg ttgcggtatc tggtgaggta tcataaacct taaagtctac
     1081 tccgactccc agatcagctt gagccagctg attgaccatg gtcatatgag ccagttcctt
     1141 gatattgttt tccttagata aatgcccaag gtaaatcttc ttagtacgat ttcctagcgt
     1201 ccgaatcata gcttcagcac cgtcctcgtt agaaaggtga ccaaggtcag ataggattcg
     1261 ttgtttgagt cgccaagcgt aagaacctga tcgcaaaatc tctacatcat ggttggcctc
     1321 gataagatag ccatccgcat tttcgacaat gcccgccata cggtcactga cataacctgt
     1381 atctgtcaaa aggacaaaac tcttatcatc cttcataaag cgatagaact gcggtgcgac
     1441 tgcatcatgg cttacaccaa aactctcgat gtcgatatct ccaaaggttt tggttttacc
     1501 catttcaaaa atatgctttt gcgaagaatc caccttgcca agatatttac tattttccat
     1561 agcttgccag gtcttttcat tggcataaag atccatacca tacttgcgag ccaaaacgcc
     1621 tactccatgg atatgatctg aatgctcatg ggtaatcaag atggcatcca ggtcttctgg
     1681 cttgcggtta atttcagcta gcagactggt aattttcttg ccagacaagc ctgcatccac
     1741 taaaagcttc ttttttgagg tttccagata aaaagaattt ccactggaac ccgacgctaa
     1801 aatactgtat ttaaagccta tttcactcat tctagtcttc tacttcatcc tcccatactt
     1861 cttctttcac tgcatcctta tcataaggga gcacaatggt aaaggttgaa cccttgccgt
     1921 attcactctt ggcccaaata aagcccttat gttgtttaat aatttcttta gcgatagaca
     1981 gtcctagacc tgtaccacct tgtgcacgac ttctagcacg atccacacga tagaaacggt
     2041 caaagatacg tggtaaatcc tgcttaggaa tccccaaacc gtggtcagaa atggataaaa
     2101 tcatctggtc ttcagttgtc ttcattctga cagtgatttt acccccatct ggcgaatact
     2161 taatagcatt atttaaaata ttgtcgacaa cctgcgtcat cttatctgta tcaatttcca
     2221 tccagataga attgatggga taatctctca ccaactcata ttttttctcc ttttcctgtc
     2281 ctttcatctt gtcaaaacga ttgaggataa aggtaataaa agcagtgaag ttaatcagtt
     2341 ccacatctag gtgactggta gcattatcaa tacgtgaaag atggaggaga tccgtcacca
     2401 tgcgcatcat acggttggtc tcatcaagag aaaccttgat aaagtctggt gctacagttt
     2461 cacacaaagc cccctcatcc aaggcttcaa gataggattt tacgctagtc agaggagtcc
     2521 gtaactcatg gctaacattg gaaacaaaga gtcttcgttc gcgttcttcc ttctcctgct
     2581 ccgtcgtatc atgcaaaaca gccaccaaac ctgaaataaa gccagactct cgacgtatca
     2641 aggcaaagcg aactcgaagg ttcaaatatt caccattgat atcttgggaa tctagcaaca
     2701 attctggact ttgggtaatc aaatcacgca attcatagtt ttcttctatc ttgagcaatt
     2761 ccaaaatgct tctattcaga acatcttcct taaccaaccc cagttgcttc ttggctgtat
     2821 cgttaatcat gataatctga ccccgacggt tggtcgcaag aaccccatct gtcatataaa
     2881 acagaatact atttagcctc ttactctctt gttctagatt ttcctgagtg agacgaataa
     2941 cctccgacaa gtcattcaaa ttattggtaa tattggtgat ttcagaccca ccttgcatat
     3001 caagaacctt ggaataatct cctgcaatca aatctttaac cttttgattg atttgcttca
     3061 actgaatatt atcacgtcta ttttccagta ataagagggt cacaacaagg atgaaaccta
     3121 acaaaatcag gataaagata aaatctctgg taaaaatggt ttgtttcagt aaatcaagca
     3181 ttatttctca tgtaataccc tacaccacgg cgcgtcaaga tatactctgg tcggctgggc
     3241 gtatcttcaa tcttctcacg cagacgtcgt acagtcacat caactgtacg gacatcacca
     3301 aaatagtcat aaccccagac agtctcaagc aagtgttcgc gcgtgatgac ttgacctgta
     3361 tgcgatgcta aatgatacaa aagctcaaat tcacgatggg ttaagtctag ttcttcgcca
     3421 tattttttag ccacgtaggc gtctggaaca atttctaaat ccccaatttg gataggttga
     3481 ggtttactat ctgcttcctg accatctact ggcataggtt gagaacgacg cagaagagct
     3541 ttaacacgcg cctgcaactc acgattggag aagggtttcg ttacatagtc atctgcccca
     3601 agttccaaac cgataacctt atcaaattca ctatctttgg ctgaaagcat aagaatgggc
     3661 acactgcttg tcttacgaat ggtcttagca acttctaaac catcaatttc tggaagcatc
     3721 aaatccagaa taataatatc tggttgctct gcttcaaatt gctctagcgc ttcacgacca
     3781 ttaaaagcag ttacaacttc gtaaccttcc ttggtcatat taaacttgat aatatccgag
     3841 attggtttct catcatctac aattagtatt tttttcatat gttcaccttt ttctctacta
     3901 ttataccaaa aaatagtcag aagacacaat agctagtctt ggctactgtc taagttggct
     3961 tgtgcataag cctgccagat tttttgttgg ggtttggcaa gtgggtaatt cttgaattct
     4021 tctggtgaaa gccaacgaac ttccctatct gaaaaatcat ggaagtcact cacctgacct
     4081 gctacaatct gtacatgcca ttttcgatga ctaaaaacat gctggactgt atcaaaacaa
     4141 acatcaagcc aatcaacatc taggtcatag tcctgctgga aactctcttc tggactgggg
     4201 ccagagttca cactttcttc cgcaacctga tgaaagaggt caaactgctc ttcttgcgaa
     4261 aagttatcaa cttctataaa ggggaaatgc caaaaacctg ccaagagctt ttcgctttca
     4321 tttttttcaa gtaaaaattg tccttgagaa tttttcacaa ctaaggcttt aagataaata
     4381 ggaaccggct ttttcttagg agatttaatt ggataacggt ccatggttcc attctgatat
     4441 gccgcactaa agtccttgac tgggctttct tcaggtctgg gatttacagg agactcaata
     4501 tcagacccta agtccatcaa ggcttgatta aaatcacccg gacgatctgg attaatcaag
     4561 atctccatca ttgcctgaaa aatttttcga ttacttggaa tcccaatatc gtggttgact
     4621 tcaaacagac gcgccaagac ccgcatgaca ttaccatcta cagctggctc aggcaagtta
     4681 aaagcaatac tggaaatggc tcctgctgtg taaggtccaa tccctttcaa gctggaaatt
     4741 ccttcatagg tatttggaaa ttggccacca aagtcagtca taatctgctg ggctgcagcc
     4801 tgcatattgc gaactcgaga ataataaccc aagccctccc aagctttcag taaactctcc
     4861 tcaggcgcag ttgccagact ttcgacagtt ggaaaccagt ccaaaaatct ttcgtagtaa
     4921 gggataactg tatccaccct ggtctgctga agcatgattt cagataccca gatgtgataa
     4981 ggatttttac ttctcctcca aggcaaatct cttttgtttt catcatacca agcgagaagt
     5041 ttctcacgga aagaaatgac tttctcctcc ggccacatga cgataccgta ttctttcaaa
     5101 tctaacatat ctctagtata acacagaagg tttcacctgt ctttgtatct gatttataat
     5161 attttcaata gatagtatat aacttttcta tctacttata ctcaatgaaa atcaaagagc
     5221 aaactaggaa gctagccgca ggttgctcaa aacactgttt tgaggttgtg gatagaactg
     5281 acagagtcag tatcatatta cctacggcaa ggtgaagctg acgtagtttg aaaagatttt
     5341 cgaagagtat aaatcttatt gatgaactgc ttgcagtctg agaaaaaatg agcttggata
     5401 ttatttccaa actcacttaa agtcaatttc aatccactag aacaagccta gtacagttcc
     5461 atcgctttca acatccatgt tgagagctgc tggacgtttt ggaagacctg gcatggtcat
     5521 aacatcacca gttaaggcaa cgatgaagcc tgcacctaat tttggtacca attcacgaat
     5581 ggtaatttca aagttttctg gtgctccaag cgcatttgga ttgtctgaga aactgtattg
     5641 agttttagcc atacaaattg gcaatttgtc ccaaccgttt tgaacgattt gagcaatttg
     5701 tgtttgagct ttcttctcaa agttcacttt gctaccacga tagatttcag tgacaatttt
     5761 ttcaatcttt tcttggacag aaaggtcatt atcgtacaaa cgtttatagt tagctggatt
     5821 ttcagcaatt gtcttaacaa ctgtttcggc aagtgctact ccaccttctg ctccatcagc
     5881 ccagacacta gccaattcaa ctggtacatc gattgaggca cagagttctt ttaaggctgc
     5941 aatttcagct tctgtatcag atacaaattc gttaatagct acaactgctg gaataccgaa
     6001 cttacggata ttttcaacgt ggcgtttcaa gttagcaaaa cctgcacgaa ctgcctctac
     6061 attttcttca gtcagagcgt ctttagccac accaccattc atcttaaggg cacgaagggt
     6121 tgcgacaata acaactgcat ctggagatgt tggcaagttt ggtgtcttga tatcaaggaa
     6181 tttctcagca ccaaggtccg caccaaaacc agcttcagta acagtgtaat cagccaagtg
     6241 aagggctgtt gtcgtcgcca aaacagagtt acagccatga gcgatattgg caaatggacc
     6301 accgtgtaca aaggcaggtg taccgtaaat tgtctgaacc aagtttggct taatagcatc
     6361 cttcaaaatc aaagccaagg caccctcaac ctgcaaatca cctacagaaa caggcgtacg
     6421 gtcatagcga taaccaataa cgatattcgc caaacgacgt ttcaagtcct cgatgtccgt
     6481 tgccaagcaa agaattgcca tgatttctga agcaactgta atatcaaaac catcctcacg
     6541 tggaataccg tttagaggac caccaagacc aacagtcaca tggcggagcg cacggtcgtt
     6601 caagtccaca acgcgtttcc agaggatacg acgttgatca attcccagct cattcccttg
     6661 gtgcaagtgg ttgtcaatca aggcagaaag ggcattgttg gcagttgtaa tagcatgcat
     6721 atctccagta aagtggaggt tgatgtcttc cattggcaga acttgtgcat acccaccacc
     6781 agcagcacca cccttgatcc ccatgactgg accaagagac ggttcgcgga tagcaatcat
     6841 ggttttcttg ccaatcttgt tcaaggcatc cgcaagacca atggtaagcg tcgactttcc
     6901 ttcacctgca ggtgttgggt tgatggcagt aaccaagatc aatttaccga ctggattgct
     6961 ctcaactgca cgaattttat caaagctgag tttagccttg tactttccgt acaactccaa
     7021 atcgtcgtaa gaaataccaa gtttctctac aacatcaaca attggcttca actcaatact
     7081 ctgtgcgatt tcaatatctg ttttcattca aaattcctct aacctcttat atgataattc
     7141 attatatcac aaaacaagat ttttaacatc ctaaaactct ctaaacgttc gtaaatatct
     7201 ctgtttttaa gacttttaga gtcctttctt aaatttttta tggctttata gtttgaaact
     7261 ataataaatc ttcgttttta ccaaaaattt atcactttca ttttacttac cgcttatttt
     7321 tgtgtacaat agtgctatga aaattttagt tacatcgggc ggtaccagtg aagctatcga
     7381 tagcgtccgc tctatcacta accattctac aggtcacttg gggaaaatta tcacagagac
     7441 tttgcttttt gcagggcatg aagtttgttt aattacgaca aaacgagctc tgaagccaga
     7501 gcctcatcct aacctaagta ttcgagaaat taccaatacc aaggaccttc taatagaaat
     7561 gcaagaacgt gttcaggatt atcaggtctt gatccactca atggctgttt ctgactacac
     7621 tcctgtttat atgacagggc ttgaggaagt tcaggctagc tccaatctaa aagaattttt
     7681 aagcaagcag aatcatcagg ccaagatttc ttcaactgat gaggttcagg ttttgttcct
     7741 taaaaagaca cccaaaatca tatccctagt caaggaatgg aatcctacta ttcatctgat
     7801 tggtttcaaa ctgctggttg atgttaccga agatcatctg gttgacattg cacgaaaaag
     7861 tcttatcaag aatcaagcag atttaatcat cgcgaatgac ctgactcaaa tttcaacaga
     7921 tcagcaccga gctatatttg ttgagaaaaa tcagcttcaa acagtccaga ctaaagaaga
     7981 aattgcagaa ctcctccttg aaaaaattca agcctatcat tcttagaaag gaaaactatg
     8041 gcaaacattc tcttggctgt aacgggttca atcgcctctt ataagtcggc agatttagtc
     8101 agttctctaa aaaaacaagg ccatcaagtc actgtcttaa tgactcaggc tgctacagag
     8161 tttatccaac ctttgacact acaggtactc tcacagaatc ctgtccactt ggatgtcatg
     8221 aaggaaccct atcctgatca ggtcaatcat atcgaacttg gaaaaaaagc agatttattt
     8281 atcgtggtac ctgcaactgc taacactatt gcaaaactag ctcacggatt tgcggacaac
     8341 atggtaacca gtacagctct agccctacca agtcatattc ccaaactaat aactcctgct
     8401 atgaatacaa aaatgtatga ccatccagta actcagaata atctgaaaac attagaaacc
     8461 tacggctatc agctgattgc tcctaaggaa tccctactag cttgtggaga ccacggacga
     8521 ggagctttag ctgacctcac aattatttta gaaagaataa aggaaactat cgatgaaaaa
     8581 acgctctaat attgcaccca ttgctatctt ttttgctacc atgctcgtga tacactttct
     8641 gagctcactt atctttaacc tttttccatt tccaatcaaa ccgaccattg ttcatattcc
     8701 tgtcattatt gccagcatta tttatggtcc acgagttggg gttacacttg gatttttgat
     8761 gggattactt agcttgacgg ttaacacgat tacgattcta ccgacaagct acctcttctc
     8821 tcccttcgta ccaaacggaa acatctactc agctatcatt gccattgtcc cacgtatttt
     8881 gattggttta actccttact tagtctataa actgatgaaa aacaagactg gtctgatttt
     8941 agctggggcc cttggttcct tgacaaatac tatctttgtc cttggaggaa tcttcttcct
     9001 atttggaaat gtttataatg gaaatatcca acttcttctg gcaaccgtta tctcaacaaa
     9061 ttcaattgct gaattggtca tttctgcaat tctaacccta gccattgttc cacgactaca
     9121 aaccttgaaa aaataaaaac aatctccgct ttcaaacctg aaggtggaga ttttgctcta
     9181 tacagtttct ttttaatgaa atctttacta tagtaaaacg aaataagaac aggacaaatc
     9241 gatcaggaca gccaaatcga tttctaacaa tgttttagaa gtagaggtgg actattctag
     9301 tttcaatcta ctataacttt taactaaaaa atgatctata aacccaagta aattcttgct
     9361 ttattgtctg gtttattgta ccatactagt gtatatgcag ttaaaaagga gattcttgtg
     9421 aatacacgga aaaagacaca atttatgaca atgacagccc ttttaacggc tattgcgatt
     9481 ttgattccaa ttgttatgcc tttcaagatt gtcattccac ctgcttccta tactttgggg
     9541 agccacatcg ctatttttat agccatgttc ttgtcgccct tgatggcagt ttttgtcatc
     9601 ctagcctcta gttttggatt tttgatggct ggctatccca tggttatcgt ttttcgggct
     9661 ttttcccata tatcttttgg tgctttagga gctctttacc tacaaaaatt ccccgatacc
     9721 ctagataaac caaaatcttc ctgggttttc aactttgttt tggctgttgt tcatgccctt
     9781 gctgaagtat tagcctgtgt ccttttttac gcaacttcgg gtaccaatgt agaaaacatg
     9841 ttctatgttc tatttgtact agttggattt ggcacaatta tccatagtat ggtagactat
     9901 acattagcac tagctgtcta taaagtgctt cgaaaacgcc gttaaaagga aaagctatga
     9961 caaaagatcg caaacaagcc ctgctccaac tcttgaaaga agctcctaaa gcccttaatg
    10021 gccaaagttt ggcggaacat tttcatgtca cacgtcaggt cattgtgcag gacattgcaa
    10081 ttttgagagc cgatggcgct cctatcctat ccaccaatcg tggctacatc tataagcaaa
    10141 ttgataccaa tccttatgtt cacaaacttt tcaaagtgaa acatgaagtt gaagaaatcg
    10201 gtcaggaact ccttgctatt gtcgataatg gcgggcatgt ccagaatacc ttgattgacc
    10261 atcccgttta tggagaaatt gaaaccttgc ttaaactgtc ttgtcgcaga gatgtgcaac
    10321 attttctaga acaagtcgag cattctgact ttagacctct atctgaattg acagatggca
    10381 tccattacca cctagtcgaa gccgaaacac aacaagacct ccactatatc gaggaggcct
    10441 tggatcagct aggttattta gtaaaagact agaagatttt cttttcccaa tcgtcttctg
    10501 tacggcgagg atagaaaaac tctgacttgt cgggagcttc catcatttcc atcaatggta
    10561 gcatatcata ggccagattt aagtttggaa tctggtcttt ttgcacccaa gaaacttctc
    10621 cctcttctga agattgaagg gtaccagaga actcagtcgc cttataacaa atgacaatat
    10681 agcgcccacc tgtatctagt ggccaatttt taatgccgac aagttgagga ttttggatag
    10741 tcaaccctgt ttcttcgtag atttcacgaa tgacagactc cgcaaaagcc tcatcatttt
    10801 ctacatgacc tccaggaaag gcataaccag accagcgatt gttttcaggg gcgcgatact
    10861 gcatcaccac gcgctgagtt tcgaggtctt caatcagaca gatatttgtt aaaattgtta
    10921 attgggaacg ggacataaat ttactcgctt tctaatttat taaattttca gacttactac
    10981 cagagatatt atcttt
//
LOCUS       DAVKAU010000059        10749 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVKAU010000059 DAVKAU010000000
VERSION     DAVKAU010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10749
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.059"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(110..1534)
                     /locus_tag="VWX48_001784"
     CDS             complement(110..1534)
                     /locus_tag="VWX48_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9172360.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTATILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2079..4358)
                     /gene="pulA"
                     /locus_tag="VWX48_001785"
     CDS             complement(2079..4358)
                     /gene="pulA"
                     /locus_tag="VWX48_001785"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU9172361.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTVAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4470..6428)
                     /gene="ligA"
                     /locus_tag="VWX48_001786"
     CDS             complement(4470..6428)
                     /gene="ligA"
                     /locus_tag="VWX48_001786"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU9172362.1"
                     /translation="MNKKMNELVALLNRYATEYYTSDNPSVSDSEYDHLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDKIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6521..7699)
                     /locus_tag="VWX48_001787"
     CDS             complement(6521..7699)
                     /locus_tag="VWX48_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9172363.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSIIVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FFLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7779..8642)
                     /locus_tag="VWX48_001788"
     CDS             complement(7779..8642)
                     /locus_tag="VWX48_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9172364.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQETMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8645..10546)
                     /locus_tag="VWX48_001789"
     CDS             complement(8645..10546)
                     /locus_tag="VWX48_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9172365.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAKIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3229 a         2358 c         1911 g         3251 t
ORIGIN      
        1 ctattctgat ttcaatctat tataatacca aaaagttcgt attttttcta taattattat
       61 tttatagcaa aaaaataaaa ccaggaaaac aatttcctgg ttttacacgt tatttcacat
      121 caaaaacaat ggatttgaca tttgtcatcg cttcaatgct atatttaatt ccttgcactc
      181 cagctccaga acctttgaca ccaaggaatg ggaaattatc tggaccacgc tgggttttat
      241 tattaatgtg gactgtacct acttcaagct tttcagcaat ttcaaaggct tttttgaaat
      301 catttgtaaa gactgatgat tgaaggccga attcagattc gttggcaaag gcaatagctt
      361 cctctacact agccacacga atgattggta aaacaggacc aaatggctct tcccatgcca
      421 ctttcatatc ttttgtaact tggtcaaaaa gcactggcca gaggagattg ccctcacgtt
      481 tgattggtgt aagagcctga gcctcttttt cttgtgcatc ctcaatcaag ccccaaatga
      541 agtcggctga agcattgtca ataacaggtg taatatcagc attgtcaaat ggatcaccaa
      601 ctgttaattt agaaacttct tcctgaagca aagtagctaa tttatctgct acactttcga
      661 gaacaatgac acgtttaatg gccgtgcaac gttgtcctga gtagctaaag gctcccgcaa
      721 caatttgctt ggcagcatgt tccaaatctg catcttctag tacaagagct gcatctttcc
      781 caccaagttc caacatgata ggacgcatac cagctaaacg accaatacgt tctccaatag
      841 gagttgaacc tgtaaagttg atgaagttga cttctttgtg ctcaatgata taatccccaa
      901 tttctgaacc acgacctgta atggtgttga aaacacctgc cggaatccct gcttcttcaa
      961 atgctttagc caacaagagt ccagaaatgg aaccttgtgt tggtggcttc aacatgacca
     1021 cattccctgc aatcaaggca ggtgcaattt tagaagcaga taaattaact ggataattaa
     1081 agggagcaat cgctagcacg ataccaactg gttcacgacg gacaacagcc agtttgtttt
     1141 tacttgctgc ctcaaaacca ccaccttcca ttgcttgtcc agtgatacgg agaccttcct
     1201 cagcagcata acgaatcaag tctgctgtac gcactacttc tccaattgct gctttaatcc
     1261 cttttgctac ttctttggca aggatagtac caattttttc cttatcgcgt tctaaaatag
     1321 ttgctgtttt atgcaaataa gccgcacgtt caattgctga taaagctcgc catgctggta
     1381 gggctgcacg cgcagcttgc atagcctcat cagcttcagt ctgagtcatg gctggaactg
     1441 tacccaattc ttcttgattg attggtgaat aaatcgtaat ttcttgttca gatgatttcc
     1501 attttccatt tactaaattc tgatatcttg tcaaattctt gtcctcctga aaatgattaa
     1561 gatatatttt accaaatttt cagaaaatca caaccctttt tgcaaaattt ttgagattat
     1621 tttcacaagc ttgatttttc aaagtatact caataaaaat aaaaaaaatc cactacatca
     1681 aggcgagact aatgtggttt gaagaaattt tcgaagagcg tgaatgagta tcatctatag
     1741 taaaataaaa aaactgaaca atttggttgg ggacagtcaa accaatttct cacaatgttt
     1801 tagaaacaag ggtgtgctat tccaatttca ggctactata actgtcatag attgctgaaa
     1861 caaagtctag gtaaaagtct tcataataaa aagaccccct atcaagtgtt caaaaacttt
     1921 gataggaggt cttgttttgt gaaaatattt atcaaatttt ctatacaagt gagctgttag
     1981 ccaggttctt tctattcttt caatttcaat gaatggattt tttaccaata ctcataactg
     2041 ggaatttgtc tgtctaaaaa tagcgagata gatggtattt ataaaacact caagacagct
     2101 agactaatat catttaaaac attatcttct tttgagcgac tgttggttac caacatagct
     2161 aaatttcctg cattttcaaa ttgatagggt tctgatttag cattcacaac taccaagagg
     2221 tgttctttgc cgtgaacttc atagataagg cagccgctat gttcaatcgc agaatgcaca
     2281 aagacatgat ggtaaatttc atcatagcta gagtaagaaa aagcaacagt ttttgtcttc
     2341 aatcggatga cttgacggat aaactcaata ctgtcttgac gctcattaat caagttccag
     2401 ttcacttggt tcacactgtc aggagcatta tagctattca tcgcacgctc tctatcatca
     2461 tgggtcaact caccattttc accagtcgca accagtttgg tacgaccaaa ttcttgaccg
     2521 atttccataa aggccatccc ctgcatgagc agattcatgg ctgtggcagt ttcgaccttg
     2581 cgcatgattt gctctgaact ttggtctgga tgaagggttg ccaataaatc gtgaagattg
     2641 taattgtcat gggcttctac atagttaagc acctgatttg gatgtgtata ggttcctaat
     2701 tcacgacttc ctaggattgc tttagctaga attggctctg tcgcagcacc actgacaaaa
     2761 cctgacttga tagcaccata aacttctccc cctttgacag catcgcgctg attgtcatta
     2821 aagaaaccaa tatttggcat ctggtaggca ttgtccttct tggccttatc ataaggggta
     2881 agacctgttc ccatatccca tccttctcca tagaggataa tgttggagtc gatttcatcc
     2941 aagctttgac gaatcatctg catggtcttg acatcatgaa tccccatcaa gtcaaaacgg
     3001 aagccgtcaa tattatattc ctgcacccag tatagaagag aatcaatcat atacttgcga
     3061 aacatttcgt gttcactggc tgtttcattt ccaacacccg ttccattctg gaaggtacca
     3121 tctggattca tacgataata gtaatcaggg actgttgttt ggaatggtgc atcaacaact
     3181 gagaaggtat ggttatagac tacatccata atgactccaa tacccgcatc gtgataagct
     3241 tgaaccatca ccttcaaatc acgaatgacc tgagctggat catctggatt agttgaaaaa
     3301 ctagtttctg gcgcgttata gttttgtgga tcataacccc agttgtaggt tacatttcca
     3361 tcctcatcgt attctttatg acggtctgca attggttgca attgaacata attgtagccc
     3421 agcttcttga tgtaatcaaa agcagttgac tggccgtatt ggttaactgt tccagcctga
     3481 gcagcaccca agaaagttcc tcgaagatgt tcatctacac ccgatgtagg tgatttagtc
     3541 aaatcacgaa tgtgcatttc acagataact gccttacatg gattttccaa gcgccaagta
     3601 gcctccgaac cgtgcttaac ctcgaagttt tcaacttgct tttctacatg gctcagaata
     3661 gctgaacgtt tgccatcagg gctggtcgcg attgtataag gatcacgtgt cagtgtttgg
     3721 tgatgaggga attggacttg atactgataa gtcttaccta ccaaatcttc ttcaacatcc
     3781 aaactccaga caccgattgt attgtcctta tgattataag agtagctatt gcctcttttc
     3841 atctcaaaag tcttccaaac gggtgcatca ttagcagctg attcataaac gacaacttgc
     3901 acttctgtcg ctgtaggtga ccagagggaa aaatgagcct gattgtcctc tacacggcaa
     3961 cccaattctc cttggtaacc ccaatgatga tcaaaactag cactgttaat ggccttatca
     4021 aaggcaaaag gattttgatt tttatagaaa ggactggcaa tagcaggatt ttcagagtaa
     4081 taaatcctat catcgccttc caaaatccag acctctgtta ataggggata gtgattaaaa
     4141 cggatagaat attctttact agtttgacct gtatgaacca caaaattcaa gctttctata
     4201 acatgtgaac ttgggtgttc aaagctaaat aaagctccaa aataatcttc tttgtaggtt
     4261 agcaaatcaa ttcgttgatc ctgacttttt acaaaggagc aagtgtcata ttctccattc
     4321 ttacgatggt aatgaatgcg catagggtag ttatacattt tttatttttc ctttttactt
     4381 tgtttctatt tcactaataa atttttgtca atctcgtctc aattaacaga catagtcata
     4441 ttctctaaac tctgttttta aacgatccat tacaaacttt ctagccatgc ctcatctctg
     4501 acctggatac caagttcttg tgctttttgc agtttacttc cagcgtctgc acctaccacg
     4561 acgaggtcgg tctttttaga aacactacct gtcactttgg cacccagact ttcgagttta
     4621 cttttagctt ctgagcgctt gagtcgttcc aattttcctg tcaataccac ggtcaaacct
     4681 gacaaggccg catccgctac taccgtctgt cctttatagt ccagattgac cccagtttct
     4741 ttcaattctc tgagcagaat ttcagagcct tctgtcgcaa aataagtctg aagacttttg
     4801 gcaatcacgc cacctagact ttcaatacta gccacttcct ctgaatctgc ctgatacaga
     4861 ttttcaattg aatggaaata ttgaagtaaa agctgactag ccttgcttcc gacatgacga
     4921 attcccaaac caaataagag cttctcggca gaattttcct ttgatgcttg gatagcctga
     4981 tacagtttag cagcggactt ttccttaacc ccctctaaaa ggaggaaatc ctcttcttgc
     5041 aaacgataaa tatccgccac atccttgact aaattagcag caaaaagctt ctcaacaata
     5101 gatggaccaa ggcctgtaat attcatagca tcacgagaag caaagtgaat caagccttcc
     5161 atgatttgag cagggcaacg cggattgata caacgtaggg ccacttcatc ttcaaagtgc
     5221 aacaagtcag agttacaact tggacagttt gtagggatat ctagtttttc ttcagaaacc
     5281 cgtttggact ctaccacacg taaaacggca gggatgatgt caccagcctt atatacaatg
     5341 accgtatcgt cttttcggat atctttttca gcaatataat ctacattgtg cagggtcgca
     5401 cggctaacag tcgtaccggc aagttgtact ggtgttagat tagcagttgg agttacaaca
     5461 ccggtacggc caactgtcca gtcaactgat aagagttgag cttctttttc ttcagcaggg
     5521 aacttgtagg ctactgccca ctttggagcc ttaacggtaa aaccaagttc ttcttgactt
     5581 gctaggtcgt tgaccttgat taccactcca tcaatatcgt aaggcagatt ttcccgttcc
     5641 tgtcctactt cttggataaa attccagatt ttatctatgt tttcagccaa gattcgctta
     5701 ggattgacca caaaacctag ttgttctagg tacttcaaac ccttttcttg gctatcacga
     5761 gttgaagggc tggcttcttg atagagaaac gttgcaagat tacgcttggc aactactgct
     5821 gtatccaact gacgcagagt tcctgctgcc gcattacgag gattagcaaa ttcaggctct
     5881 ccattttctt ggcgcacttg gttaacttgg tcaaaggaag cgcgtggcat gtaacattcc
     5941 ccacgaactg tgatatctag ttcttctggc aaagtcaaag ggatgtcctt aacacgcttg
     6001 aggttttctg tgatattttc accaattgaa ccatctccac gtgttacccc agcaaccaaa
     6061 atcccctttt cataagtcag cgagatagat aagccatcga ttttcagctc acaaatatag
     6121 gtcggatgag caacttcctt acgaacacgc gcatcaaaag catctagctc ctcacgtgaa
     6181 aaagcatcct gcaaactata aagaggatac tgatgactgt atttttcaaa accatctaaa
     6241 accttgccac caacacgatg agtcggacta tctgctagca cttgctctgg ataagcagtt
     6301 tctaactcga ccaactcacg gtaaaggtgg tcatactcac tgtctgaaac cgagggatta
     6361 tcgctggtat agtactcagt cgcatagcga ttgagcaaag cgactaactc attcattttt
     6421 ttattcataa gaccatttta ccataaaaca aaccctcctc acaaacgaga agggcggaaa
     6481 aaacacttag tttgaaatta tttttgaaac tcaagcaacc ttatatcaat ttttcaaaat
     6541 gagttcgaac ataaataaac gatatacaag acaagatgat aacaccactt ccaattatca
     6601 ggaaagaaga gagatgtaca cttggcaaga ctgtcataaa tccttttgca ataggcataa
     6661 atagaatagc taaggtaaaa attgtactca gtactcttcc aagaaattcg ctctcaacct
     6721 tggtttgtac ttgagtaaaa aagtgaatat taaaaatcgt cataaacaat tcacaaacta
     6781 aatttccaga aaaggaaaga aaagttggaa gtggtaatcc catcataaaa actccgacac
     6841 ctgtcaaagc cagtaaaatc aaaagattat aaatattagc tttaatttta ctagctagaa
     6901 gagccccaat gatggaacca atagccccca tagttaaaat acttgcatag gctccttctg
     6961 acccgtaaag ctgatttgaa aagggaagta gaaattcaaa agctgcaaaa aagaaattaa
     7021 cgctggaagc taccagcaaa aagaagaaaa tttcttgctg atgccagata tagtgtaacc
     7081 catccttgat atctacaaaa atatctctcc cagtaaaagc ctttttctct tgaacttttg
     7141 cttcctcttt tggaaggaaa gccactagaa caaaagcaat gaaaaaagtc agcgagtcta
     7201 gcagtagcgt catatggaga cttgcaaact gtaaaacaag gaaggaaaga acaggagagc
     7261 taacacctac aacctgcaaa accagctcta agcgagaatt atagatcaca atctcatctt
     7321 tctccaccac ttcagttatg atagctttat tggctgtgcg agaaaaggca aaagcaatag
     7381 cctgcacaat gttagcaaca atcaaagcgc caatcatcca gctatcattc cttatgaaag
     7441 aaatagccag acaaagaatc ccacaaacaa gatctgccgt cattaaaatc ttacgacgag
     7501 aaaaacggtc tgaaataact ccgccaaagg gattgacgat aatagatgtg acgagctcag
     7561 aaatctgata cattcctaaa actgtctgtc ctatagtccc catagaagcc aaccagacac
     7621 tatttccata atcatagagc atatttccca ttttattgat agccccacgg ctaatcaact
     7681 gcactgcata gcgattcata ttaaagctcc tctcaaattt tgaaactatt gtatcaaaac
     7741 cgaaaggagc tttttatttt ttcccttatt tgggaaaatt aacttttgac aaatttttcg
     7801 tagtgttcct gataataggc tacttgctct ggaagaccta acacatcaaa aatatgcatg
     7861 gtctcttgca tctgcttaca gccttcttta cactgtcctt tttgatataa ggcaaaacct
     7921 tttaaataat ggaaaacatt acgctcataa agcttaatac ctttgtcaat aatcttctct
     7981 gtataagcct caaaatagtt ggcattataa aaagaagaat gctctaaaca atgctggtaa
     8041 caattgaggg ccaaaatcaa cactaatctc ttatggcgac taatctcttg gtaaaattcc
     8101 tccctctcca taacttctct accaatccga gtgacatagt ctacatcgta gaaactatag
     8161 aggttaccga aaagaatcaa ctcatacatg gtccattctt ctgttttgaa gagataatct
     8221 gctaccttat ccaaatcatc ctgcttcata tcataactcg catctctttg acaaatcaga
     8281 ccttgtagca aaatccagtt cagctcaaaa taaaggggag tcgtcgaact cttagacttt
     8341 tcaagttgtt ctctttgaag cttttgaaaa cctgcaatat cgtttgaata gtaaagtggg
     8401 ataatctgtg ccatcataga cacatgttca tgattatgaa aattccttgc cttatccatg
     8461 aaattttcga ttgttacatg aatgttatcc aaaatctcaa agaaacggga gactgccagg
     8521 tcagactccc caagctcaaa gcgagataac tgagaggtag agcaggattc gcctgctgct
     8581 tcctttaaag aataatttcc acttgttcga aattcacgaa atacttttcc aagatgttcc
     8641 atctttacac ctgatctgat aattcttccc actcaagcat agcttcttcc tgacgatggc
     8701 tgattttgtc cagctcagcc tgtaattcca tgagtttgtc ggcatcgttt gtttccaaca
     8761 tttgttcaga aatggcttgg ctttgacttt ctagctcttc aattttagct tctagacttt
     8821 cgatttgtcg catgagtttg cgaacttctt tttgactttc tttctgggcc tgatagtcat
     8881 tgactggact tgcttccttt gcttgattgc tagttgaagc ttcctcagtc tgactcattt
     8941 ctgctgttgc tttcttctca acatagtagt cgtaatctcc aaggtagaga gttgaaccat
     9001 tctcagacaa ttccaaaaca tgagttgcca cacgattgat aaagtaacga tcatgactga
     9061 caaaaagcaa ggtaccatca aagtcaatca aagcattttc caacacttcc ttgctatcaa
     9121 tatccaagtg gttggtcggc tcgtcaagga tcaggaagtt gttgttttcc atagacaatt
     9181 tagctaaaag caaacgagct ttttcgccac cagatagcat gccgactgat tttttaacat
     9241 catctcctga gaaaaggaag gctccaagac ggttgcggat ttcaacttct ggtgtcagtt
     9301 tgaaatcatt ccagagttca tccagcaccg tattacttgg tgtcagcttg ctttgggttt
     9361 ggtcatagta accaacctca acattagcgc caaagcgctt ttcacctttg ataaaaggaa
     9421 tctggtccac aatagacttg ataaaggttg acttgccgat accatttgga ccaacgatag
     9481 cgacagcatt catcttacga agatctaggt tgataggttg tgacaagact tccccgtcat
     9541 aaccaatagc agtattttca acagtcaaaa caacattgcc cgacgttttt tcagactgga
     9601 aggtcatgtt ggctgctttc ttgccagctt caggcttgtc caaacgctcc attttttcta
     9661 gttgtttacg gcgagattga gcacgtttag tcgttgaagc acgaactaga ttgcgattga
     9721 caaagtcttc cagagcagcg atttccttct gttgcttttc atagtttttt gcctcagtag
     9781 ctagcttttg ctccttcaat tcgacaaaac gagagtaatt ccccacatag cgatccaagg
     9841 aatgcttggt caaatctagc gtaattgtcg caaccttgtc caagaaataa cggtcgtggc
     9901 tgacgataat gagggcaccg ctatagttta ccaagtaatt ctctagccag gcgatggttt
     9961 caatatccaa gtggttagtt ggctcgtcca agaccaagag attgggcttt tcaaggagca
    10021 ttttggcaag tgccaaacga gtattttgac caccagaaag ctcagcaatt ttcatctgcc
    10081 acatagactc gtcaaacttg aatccattca aaatcgctcg aatatcagct tcataggtaa
    10141 agccacctgc ttggcgaaaa ttctcagata agcggtcata atctgacatc agtttatcca
    10201 aatcctcacc agacttttca cccatctcca gctccatctg acgcagttgt ctctccgtcc
    10261 gacgcaaatc attaaagaca tgaagcattt catcgtagat ggtattttca gactcaaaac
    10321 ggctatcttg ggctaggtaa gacagagaaa tatctttttt cttattgatt tctccgctag
    10381 ttggctcctc ttctccaact aaaatcttca aaagagtaga cttacctgca ccatttttcc
    10441 caacaagagc aatccgatct cgttcatcaa cctgcaggtt gatattatcg aaaagaacct
    10501 ctcctgcaaa agaacgttca attttattag cttgtaaaat aatcatacaa gtagtatagc
    10561 atgtttccct aagtcattca agataatcgt aagtctttta gtacaacttt tataacataa
    10621 aataaactaa attatgtata ttttatatta gattccttca ctatcttgtt ggattttcta
    10681 accagctaat cttgtttcaa atagttatcg cacaagtcta ttatttaatt cttttcatta
    10741 tttacgtac
//
LOCUS       DAVKAU010000060        10663 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVKAU010000060 DAVKAU010000000
VERSION     DAVKAU010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.060"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(6..1220)
                     /locus_tag="VWX48_001790"
     CDS             complement(6..1220)
                     /locus_tag="VWX48_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9172366.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1376..1669)
                     /locus_tag="VWX48_001791"
     CDS             complement(1376..1669)
                     /locus_tag="VWX48_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172367.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1831..2283
                     /locus_tag="VWX48_001792"
     CDS             1831..2283
                     /locus_tag="VWX48_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU9172368.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2318..3706)
                     /locus_tag="VWX48_001793"
     CDS             complement(2318..3706)
                     /locus_tag="VWX48_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9172369.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3772..4734
                     /locus_tag="VWX48_001794"
     CDS             3772..4734
                     /locus_tag="VWX48_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU9172370.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4731..4877)
                     /locus_tag="VWX48_001795"
     CDS             complement(4731..4877)
                     /locus_tag="VWX48_001795"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172371.1"
                     /translation="MNTIERTRRLVKGCATHCFEVADETDEVSNHTYGKATLTWFAEI
                     FEEY"
     gene            complement(4941..5951)
                     /gene="ccpA"
                     /locus_tag="VWX48_001796"
     CDS             complement(4941..5951)
                     /gene="ccpA"
                     /locus_tag="VWX48_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU9172372.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6376..6975)
                     /locus_tag="VWX48_001797"
     CDS             complement(6376..6975)
                     /locus_tag="VWX48_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9172373.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQTKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(6977..8074)
                     /locus_tag="VWX48_001798"
     CDS             complement(6977..8074)
                     /locus_tag="VWX48_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9172374.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVIGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESTAAMILLELVTNIIKHAKAFKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(8074..8811)
                     /locus_tag="VWX48_001799"
     CDS             complement(8074..8811)
                     /locus_tag="VWX48_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9172375.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSSMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLASWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELIKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(8813..9697)
                     /locus_tag="VWX48_001800"
     CDS             complement(8813..9697)
                     /locus_tag="VWX48_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172376.1"
                     /translation="MNMIKVQGLHKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLSQENVIVQKLKVKELIAFFQSIY
                     PNPLSEQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTREADSFWQLLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9684..9878)
                     /locus_tag="VWX48_001801"
     CDS             complement(9684..9878)
                     /locus_tag="VWX48_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172377.1"
                     /translation="MKKATIYFFIGLSLLVWLVEMFTGWFAQTFLHQFIRGAWGLGFM
                     IFIAFPMGKELLEGEYHEHD"
     gene            complement(9875..10081)
                     /locus_tag="VWX48_001802"
     CDS             complement(9875..10081)
                     /locus_tag="VWX48_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172378.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDENFYHFPWEVFAG
                     FGMMSWLVREGLKLVRDVKKEFEK"
BASE COUNT         3273 a         2426 c         1908 g         3056 t
ORIGIN      
        1 aagccctatc tacgatactg tttcaagaaa cgagtcatct tttcttggat ttgggctaac
       61 tcatcaacac gaggaaggta aacgatacgg aagtggtctg gttcctgcca gttaaagcct
      121 cgaccatgaa ccaagagaac cttttcctgc ttcaagaaat caaggacaaa ctgctcatca
      181 tcatcgatac ggtacatatt gcggtcgatt tttgggaaga tatagagccc cgccttgggt
      241 ttaacggcag acaaacctgg aatatcttga atggcattat agatgaaatt tctttgctcg
      301 tagattcgtc caccaggaag aagcaattca tcgactgatt ggtgaccccc caaggaagtt
      361 tgtacgactt gttgggccaa aacgttagag caaaggcgca tattggacag catattgagc
      421 ccttcgatat agcccttaac atgagtctta gggccagaca agaccatcca acccacacgg
      481 aaacctgcta tgcggtggga ttttgacaga ccattcatgc tgacacagaa gacatctggt
      541 gccaagctcg ccacaggcgt atgcacatgt ccgtccatta ccatgcggtc atagatttca
      601 tccgcaaaga taatcaaatc gttttgacgg gcaatctcaa taatctccag caagagttcc
      661 ttaggataaa gggctccagt tgggttattt ggattgataa ggacaattgc cttggtattg
      721 gaagtgattt ttgacttgat atcgtcaata tctgggtacc attccacagc ttcatcacag
      781 atatagtgaa cggcatttcc tccagctagg ctgacagccg ccgtccatag aggatagtct
      841 ggcattggca ctaagacctc atccccattg tctaaaagcc cctgcatgga catgacaatc
      901 aactcactga caccatttcc aaggtaaata tcatcaatat ctacgtttgg gaatttcttc
      961 agctggcaat actgcatgat ggccttacgg gctgagaaaa tccctttgga gtcagaatag
     1021 ccttcactat cacgcgcatt cataatcaag tcatgaatga cctcgtctgg cgctgtaaag
     1081 ccaaattctg ctggatttcc tgtattcaga cgtaaaatct tttctccatt cgctcgcatc
     1141 cgcatggctt cttccaatac aggaccacgg atatcataag caacatgctc taacttacta
     1201 gacttgttat attctttcat cttgtttcct caattcatca ggatagtaac attataccac
     1261 tagaaagaga atgcgacaag tttactgaaa tgtgttacta gtttcgtata gaagaaaaac
     1321 cttgctaaag gcgaggttaa gaacgtagag atagcaggta ttttgcaaag acacatcaca
     1381 taccaaaaga taaacctaga aaaagcaagc ctagaaagga gtcataaaga agattaaaca
     1441 tgaggaaaag cccccatatc atcaagtaat cccaacgccc acttcgtttt gcaactagaa
     1501 ataagattag atggtagagt acatgaaaga ctaaaaatcc aataaaactt ggataaagaa
     1561 gcggtaccag actctctaat tgacagatca tgatcacttc taccaagact gaaactagga
     1621 taattccata ataaaggaaa tttgattttt gaaaagagtt tttcatcatt ctcccttcct
     1681 tcacttcttt cctgctatcc tttcttttat tttatcatat atttatatag agtttaagcc
     1741 ctaatattct tttgaaaaat actttttttg ctttacttct atagtgaaaa ggtttacaat
     1801 tatagtaaga aaatttcagg aggtttcatt atggcacaac gttaccaaaa tatcatggtc
     1861 gcaatcgatg gttctaagga agcggacttg gcttttgtca agggagttca ttctgctcta
     1921 cgaaacgacg ctaaactcac catcgcacat gtcattgaca cacgcgctct ccaaagcgta
     1981 tccacctttg atgctgaagt ttacgaagaa ctccaagtcg acgctgaaag tctgatgaaa
     2041 gagtacgaaa aacgtgctaa agatgctggg gtagcagatg ttcatatcgt cattgaaatg
     2101 ggaaatccaa agaccctgct agcacgtact attccagatg ccgaggaagt ggacctcatc
     2161 ctcgttggcg caactggtct caacgccttt gaacgcctct tggtcggctc ttcatctgaa
     2221 tacatactcc gccatgctaa ggtcgatttg ctggttgtga gagaacaaga aaaaacctta
     2281 taatcacaaa gaaaaggagc ccctagctcc tttttgttta cgatttattt ctctctttat
     2341 ggcgttcgta agccttgagc tggcgctgca gttccttttt aatagcaggt tctggagcat
     2401 atttttcttc ccaattatct ggttttaaga ttttatgggt cactggatca aaatgagcct
     2461 tgccatctgg aaaaattttc cccatattgg cctgatggac aatatcaaaa atacgttctg
     2521 ggtccacccc catcaagaca aaactgccgt aggtgaagta aagcgtgtca atcaaggcat
     2581 ccacttgccc tatcaaatct tgctgagcag gtgtcttctt ggctacttta cctgctgcct
     2641 tatcaagggc ctgatgaagt tgcgatacag cttgaccaaa atcttcttca gaaggactgg
     2701 ctgctcgaac aaactccacc aattcttcta ttttaaaacc agccctatgg gttgcaccct
     2761 ctaaatccca agctcgaggt tcttcttggg ttcgttcatc catcatgtgg tggaaggtct
     2821 tgaccttatt gaaatgatag tcacggctga caaagacttt ttctgaagac aaaacaccaa
     2881 aatgttccaa ggccttgtgg atcccatctt gttgattgct agtggtaatg tgcttggcag
     2941 cttccttgac actgctacta ccatttccca tagcgaccga cataccgacg ccagccagca
     3001 tttcaaggtc attatctgag tcaccaaaag ccatgacttg gttgaggtca aagccatatt
     3061 ctttcccaac tcggcgaatg ccttctaatt tagaatttcc ctgattgatg acatccgatg
     3121 caaaaggatt gctacgtgtc aatttcaagt cttcaaaatc agctgccgcc ttctcagatt
     3181 cttctggtgt catcagcatc aaaacttggt agataggctg attcatcagg tgaagcaggt
     3241 cctcttcctt ttggggaaca accttgctga ccatgcgatt aaaagactga ctcaccgtcc
     3301 gagttaaaac agagggaacg aagcgactaa ttcgttggga aaaagaaccc agaccaaagg
     3361 acatgatttt agaacccaac atggcatcct tggtccctag agcaatctcc gtgccctctt
     3421 ttttagcata gctaattaga tggcgcaaat gtaacttgga aatagggctc gtgaacaaga
     3481 ctctgtcttt actaaagata tactggccat tataggttac cgcaaaatcc agatccaaat
     3541 cgtccatcaa ttccttaaca aaaaaaggtc ctcgccctgt cgctacgcca actagtaccc
     3601 cttgttcttt gacaatctta atcgcgtcct tagtggattt caaaacactc ttgcgattgt
     3661 tgaccaaggt tccatcgata tcaaaaaaaa cagctttgac ttccatccta ttccaatctc
     3721 cccttttgtg atacaatgat tataccacat ttcagaaaga gttagtaaat catgcctaag
     3781 aaaatccttg ttttacatac gggtggaact atttccatgc aggccgatgc ttctggcgct
     3841 gttgtgacga gttcagataa tcccatgaac catgtgtcca acccacttga aggaatccaa
     3901 gtccacgcct tggacttttt taaccttcca agtccccata tcaaacccaa acatatgctg
     3961 gtcctctacc agaaaattaa agaggaagca gataactacg atggagtggt gatcacacac
     4021 ggaaccgata ctttagagga aacagcctat ttccttgata ccatggaagt tccccatatg
     4081 cctatcgttc taacaggagc catgcgtagc tccaatgagc tcggtagtga tggtgtttat
     4141 aattacctaa gtgctttacg agtggccagc gatgacaggg ctgctgacaa aggagttttg
     4201 gtcgttatga acgatgaaat ccacgctgcc aagtatgtca ccaaaacaca tacgactaat
     4261 gtcagcacct tccagactcc aacacatggc cccctcggtc tcatcatgaa acaggaaatc
     4321 ctctacttca aaacagctga acctcgtgtt cgctttgacc ttgatcacat acaaggttta
     4381 gtccctatca tctcggctta tgctggtatg acagatgagc tgattgatat gctggattta
     4441 gaacacttgg acggtttgat tatccaagcc ttcggagctg gtaatattcc caaagaaacg
     4501 gctcaaaaat tagaaagcct tctgcaaaaa ggaatcccag tcgctctggt atcacgatgc
     4561 tttaacggta ttgccgagcc tgtttatgcc taccagggtg ggggcgtaca gttgcaaaaa
     4621 gcaggcgttt tctttgttaa agaactcaac gcccaaaaag cccgcttgaa actcctcatc
     4681 gccctcaatg ccggactaac aggacaggct ttgaaagact atatggaagg ctaatactct
     4741 tcgaaaatct ctgcaaacca cgtcagcgtc gccttaccgt atgtatggtt actgacttcg
     4801 tcagtttcat ctgcaacctc aaaacagtgt gttgcgcagc ctttaaccag ccgcctagtc
     4861 cgctctatgg tattcattaa gtcaacatct cttgtttaag agcacaaaat caggaaatct
     4921 tctcgattcc ctgatttttt ctatttacgt tttcgtgttg agctacgttc tgtcaaacca
     4981 tgaggtaaga gaacttcacg ttcttccaac tcttccttat gcataatctt ggtcaacata
     5041 cgcatactaa tggcaccaag gtcataaaga ggttgggcaa tcgttgtcaa gtttggacgg
     5101 gtaaagcgtg agatttgtga atcatcacta gtaataattt caaaatcttc tggcacagaa
     5161 acacccttat cagccaaacc gttcaagact cctgctgcca actcatcacc tgtcacaact
     5221 gctgcagttg catttgatga aatcaaacgc tctgctaagg cgtaaccatc atcatagcta
     5281 tatttagatt caaataccaa accctcacta taagcgattc ctgctttttt caaggtttcc
     5341 ttgtagccaa ctaaacgaac cttaccattg atgtcatcca ctagcggacc gctaacgaaa
     5401 gcaatacgct cattttcttt agcaaggtaa ctcactgcat caattgttgc ttgcttatag
     5461 tcaatattga cacttggcaa ctggtgctca acatcgacag ttcctgcgag aacaatcgga
     5521 gtacgtgaac gcgaaaattc tgagcgaatt ttatctgtca agtgataacc catatagata
     5581 atgccatcta cctgctttga aaagagggta ttgacaacag aaacttcttt ctcgttatct
     5641 tcatcgctat tagctaggac aatattgtac ttgtacattt ctgcaatatc atcaatcccc
     5701 ttagccaaac tcgaaaaata accattggta atatttggaa tcacgacacc gacagtggtt
     5761 gtctttttac ttgcaagacc acgcgcaact gcatttggac gataatccaa acgatcaatt
     5821 acctctagca cttttttacg ggtattctct tttacatttt tattgccatt gaccacacgg
     5881 ctgaccgtcg ccatggaaac acctgcttca cgagcgacat cataaatggt tactgtatca
     5941 tctgcattca ttccttttcc tgtcctttct atctcacaca ttcttttaca agtagaggtg
     6001 ctgattgaag ctctatatct acttacaaaa gtgaagatgt gaaaatttcg ttttcatatt
     6061 tctacttatt ccattctatc actaattgta aacactttca agtgtttttt gaagattgat
     6121 tgaaaaaatt tcatagaaaa cctaggttta gctccttgct agcaccttag actaaacaaa
     6181 aaggaggaaa ctaagccctc ctaaagttat agtaaaatga aataagaaca ggataaatcg
     6241 atcaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt
     6301 ttcaatctac tataggtatt gttccattca ctaccgtcaa ttttagcaca tagtcttcat
     6361 gaaaatatta tatcatcata accaaccaga ttcttttgcg atattagctg cctctgttcg
     6421 attaccagca tccagttttg aaagaatatt ggtgacatag tttcgaatag ttccgtttga
     6481 gaggtaaagc tgatctgcga tttcttggtt ggataagccc cgggcgattc cctttaagac
     6541 agcaatctct tgttctgtca acggattggg acgggtcatc accacttcca tcaattcagg
     6601 cgaatactcc ttgcgtcctt cgaggacggt gtgcaaggtt tgcatgaggt ctgcaatgct
     6661 tcgttccttt aatacataag catccactcc agccttgacc gcacgttcaa aatacccagc
     6721 acgcttgaag gtcgtcacca caaccacctt tgtttcaagc ttttctgatc gtatccactc
     6781 caagacttca agacctgtct taacaggcat ttctacgtca aggatggcga tatctacaga
     6841 ctccttttct aatagttgga ttgcttcttg cccattcttg gtttgaagga cagactccac
     6901 atctggttga agcgtgagca attgacacat ggcatctcgc aacatacttt gatcttctgc
     6961 gactaatact ttcatcttag tttctctcct tataaggtag tcgaacttgc acttccgttg
     7021 gatgtttctg actgattaca cttacttctc ctgaaaatgg aaaaacacga tctcggactg
     7081 tatggagctc atctcctttt agaaaagcaa agccgcagcc atcatcactt actgttaaaa
     7141 tgagttcctt ctctgtccgt tctaatttta agtaagcttt aaacgctttg gcatgtttga
     7201 tgatattggt caccaactca agcaaaatca tagcagccgt cgactccaca tcctgggtca
     7261 agctagcctt gtctaagtga ttctcaactt gaacctcaat tccagcaatt tctaacatct
     7321 ttttcacagt ctctagttcg gatgtcaaag ttctagactt aagattttcc acaatggttc
     7381 gcacttcatt catggaatcc ttgctgatct ggtgaatttc ttttaattcc ttttccacct
     7441 gtggataagc ctccatctga aataactgca aggctagatc agttttaaca ctaagcatag
     7501 caaaggtatg ccccagacta tcatgcaaat cttgaccgat acgattgcgt tcattttcag
     7561 caagcaatag atttatctgg gcattttgct tagcctgtgc ttctttcaaa tcctccacaa
     7621 ttcgaatccg aaccaagcca aaagtcatta aatcgacaaa agcaagaatt acaagtagat
     7681 agaatagaaa ctcaacttcg attctctgaa aaatcaacag ttgacccaca acaaggactt
     7741 gagcaagaag aaaagtccag acatgtaaag actttaaacc acctacgctg aaatgatagc
     7801 ttaagagatt ggataggaaa aagaaaaacc agatataatt aacagccaca aaggcagtat
     7861 tcccaactac ataagtcagc aggatgcccc aatatagcca agatagacgc tggctcttag
     7921 ttgttaaaac acccaaatac gccactacaa atagaatatc aatcaataaa tgccaggcag
     7981 aaagccaccc aatcactaca ggtaggatgg ggaaaaccat aaaaattaaa ctgatccaaa
     8041 acatataatg tatgcttttc agtctttcaa gcattaagca ttctccttat gaccttgaag
     8101 gtaaatggtc aaaccaaaca aaactactga aaaaacaagt aaataaactg tggctgatag
     8161 attgattcca ccttcattta agaaggtctt gattaattcc atcaactgat atgttggaag
     8221 acacttaccc actacttgca tccagtctgg aaataaagag ataggcatcc aaagtccacc
     8281 taaaacagcc aatcctagat aaagaagatt acccacgaca gacatcagct gactagtcgg
     8341 taagagagtc aaggtcaagc caagcgctac aaaagcaata cttcccacaa tcagcaaaat
     8401 cgcagctcca acccagcttg ctagagacat gtccacacct cttacaaaat gcccaactga
     8461 gaaaaccacc aagattgaaa ccaaataatc aaccagcata cttgttatct ttgatagata
     8521 atattctacc atatttacag ggctatgacg taatgttttc tgccagttgt tcatcttgtc
     8581 ggtatgtaaa acaactggaa atgagaagat agctgtcgac atcatagaaa aggcagtcat
     8641 ggagataaga taatcacgca taaaattcgc gggtccacct ggtgtatcct ggtacatgct
     8701 agaaaagaat agatagaagg ctgtcggcat ccctactgat aataaataat agactgattg
     8761 ccgtttggtc aatagaaatt ctatcttatt taatgctatc catcgtttca tcttagtcat
     8821 ctcccttttg tgtttcttca aagattgtat ccaacaagct acgattatta acttcaattt
     8881 cttgaatcct acatcctgct tgcactaaca gttgccaaaa agaatccgct tcacgtgtaa
     8941 ctacttgcag agcatcttgt ttttgtaccc agttttcaac caagactgac ttctcaacga
     9001 cttccttgta agctagagga aggataaaat gcttttcaat ctcctcacta cgcatagcta
     9061 gaggcgtcgt atcacgaatc aactctccct tatttaaaac caaaatccgg tcagctgtat
     9121 gttctacctc ttcaatataa tgagacgaat agagaatggt gactccttgc gcttttaggt
     9181 cccgaacaat ttcccaaaaa cgttgacggg tagaggtatc catggcagca gttggctcat
     9241 ctaaaaagac aagctttggt cgaccaatca aggtcaagac gaaagaaaag agacgctttt
     9301 gtccacctga taatttttct gcaaattgtt ctttctgttg ctggtcaaac tgcaatagtt
     9361 gatcgatttc ctgctcgctc aagggatttg ggtaaatgct ttgaaagaaa gcaatcaact
     9421 ctttgacctt taatttctgt acaatcacat tttcttgaga gaggtaagcc ctagtatagt
     9481 ctaacttaga actcgtcact ggtaaacctt gaatagatac ttgaccgctg gtgaccagtt
     9541 tatctccgag caaacagtcc aaaagtgtcg tcttaccagc accattaggg ccaatcaagg
     9601 caacgcattc accttctgct acttcaaagg aaatatcctt taaaatagcc ttgcccttaa
     9661 tatttttatg taatccttga accttaatca tgttcatgat attctccttc cagcaactcc
     9721 tttcccatcg gaaaggcgat aaaaatcata aatcctaatc cccatgcacc acggatgaac
     9781 tggtgaagga aggtttgagc aaaccaacct gtaaacattt ctaccagcca taccaagagt
     9841 gacaggccga taaagaaata gatagttgct tttttcattt ttcaaactcc tttttcacat
     9901 ctcttactaa tttcaaacct tctctgacaa gccaagacat cattccaaag ccagcaaaga
     9961 cctcccaagg aaaatggtag aaattctcat ccaatcccga aaacatgaga taggtcataa
    10021 ctcctgctac tactaaactt actgcgataa tcattttatt tctcatctct tcttccccca
    10081 tttcatacta caattatagt cttttaaaat cagaggaggc agaagcttct gtcactagaa
    10141 aatatgacaa atgtcataaa aaattctgtt caaaacaagc aagatacact gtacaataaa
    10201 acacaatcag aaaaatctaa ggcaacttcc tcaaaagaga tatcaaaccc aattcacacc
    10261 ataatgtaaa ctaatactta tttaaaatca aaaagagtag aaatttttat cagacaaaca
    10321 catatatagt gtattgaatc tataacagta gggcttaaat actaaaatat ttctataaat
    10381 taatttaact ttcctgatag agctgttcat atcttatttc aattctctat attatacgtt
    10441 gaacaaaacc cttctattgc tttcttaaaa atttataaga gttataaaat ctgttaaatt
    10501 tcaatgtgta tacctaaact acggtattta ttgaaaagac tggggacaaa aagtatacgc
    10561 tgccaaaatg aattactgaa aatcaaaaaa gagagaacca aactgattcc ctcttaatgt
    10621 atataatatc tagttttaaa aatacacact cacatatctc tgt
//
LOCUS       DAVKAU010000061        10258 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVKAU010000061 DAVKAU010000000
VERSION     DAVKAU010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.061"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            5..489
                     /locus_tag="VWX48_001803"
                     /pseudo
     CDS             5..489
                     /locus_tag="VWX48_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861739.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            523..1683
                     /locus_tag="VWX48_001804"
     CDS             523..1683
                     /locus_tag="VWX48_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9172379.1"
                     /translation="MFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQN
                     GKNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEA
                     IVSDEVWQAAQVKLKSQAKRYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKK
                     DGTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQE
                     KINMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLY
                     RMYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISA
                     LISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            1951..2517
                     /locus_tag="VWX48_001805"
     CDS             1951..2517
                     /locus_tag="VWX48_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172380.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            2839..3027
                     /locus_tag="VWX48_001806"
     CDS             2839..3027
                     /locus_tag="VWX48_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU9172381.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            3089..3847
                     /locus_tag="VWX48_001807"
     CDS             3089..3847
                     /locus_tag="VWX48_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9172382.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     ISEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            3905..4759
                     /locus_tag="VWX48_001808"
     CDS             3905..4759
                     /locus_tag="VWX48_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU9172383.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            4871..5755
                     /locus_tag="VWX48_001809"
     CDS             4871..5755
                     /locus_tag="VWX48_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU9172384.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            5918..7657
                     /locus_tag="VWX48_001810"
     CDS             5918..7657
                     /locus_tag="VWX48_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEU9172385.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGEFMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            7932..8387
                     /locus_tag="VWX48_001811"
     CDS             7932..8387
                     /locus_tag="VWX48_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172386.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            8832..9308
                     /locus_tag="VWX48_001812"
     CDS             8832..9308
                     /locus_tag="VWX48_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9172387.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            9308..10069
                     /locus_tag="VWX48_001813"
     CDS             9308..10069
                     /locus_tag="VWX48_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU9172388.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFVGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLRVGEKRLNELLEK"
BASE COUNT         3609 a         1425 c         2152 g         3072 t
ORIGIN      
        1 tactatgtca aaagaaaaaa taaaagtata cctctataca cgagtatcta cgtcaataca
       61 gatagagggg tattcgttag aggcacaaaa atcacgaatg aaagcttttg ctatttacaa
      121 cgattatgaa attgttggag agtatgaaga tgccgggaag tctggcaagt ctattgaagg
      181 tagaatacag ttcaatcgaa tgatggaaga tataaaatct ggaaaagatg gagtatcttt
      241 tgttcttgtg tttaagttat caagatttgc aagaaatgcc gctgatgttc tttctacact
      301 tcagataatg caggattatg gagttaatct tatctgcgtt gaagatggca ttgattcatc
      361 taaagatgct gggaaactaa tgatttctgt tttatcagct gtggctgaaa tagaaagaga
      421 aaacatccgt attcaaacaa tggaaggtcg cattcaaagg caagggaagg aaaatggaat
      481 ggtggctttg ctccgtatgg atataaactt gaagacggca agctgtttat aaatgaggaa
      541 gaggcagttg caataagaac gattttcgac cagtatgtaa atactacgat aggagccaat
      601 gggatatcta aatacttaga gaatcatgga attagaaaaa tcccaagaca gaatggtaag
      661 aatcctttgt ttgatgcagg tcttataaga aagatattaa agaatcctgt atataatggg
      721 aaaatagcat ttggaagaag aactttagaa aaagttcatg gtacaagaaa tgaatataag
      781 caggttgaac aagatgaata tctaatatct gaagggatac atgaagctat agtttccgat
      841 gaagtttggc aagctgctca ggttaagcta aaatctcaag caaagagata tgagcatgtg
      901 aataaaggaa aagatacacg cacacacttg ctttctggaa ttgtaaaatg cccgatatgt
      961 ggagtgggaa tgtttgggaa caagtgtatc aagaaaaaga aagatggcac aaagtataaa
     1021 gatttttatt actatggttg taaacatagg cagatgataa gaggtcataa gtgtacattc
     1081 agtaagcaaa ttagagaaga attgttagat gatgctgttg cagaggtgat tgtcaagata
     1141 gtaagtaatc cgaaatttgc ttctatgatg caagaaaaaa tcaacatgaa ggtggatacc
     1201 tctgaaatag aaaaagaaat agataattac caaaaggaat tgagaaagag tcattctaca
     1261 aagtttaagc taattgagga aatagataat ttagatgttg aagataagca ttataagaga
     1321 aggaaacagg atttagatga tagactatat cgtatgtatg acaaaataga tgaattagaa
     1381 tcatcactaa ttgatgcgaa agcaaagaaa cagactattg aagctgaaaa gcttacagga
     1441 gataacatat ataaggtttt gatctatttt gataagctct ataaagtcat gaatgatgta
     1501 gagcgtaggc agttaatttc agctttgatt tctgaaattc aagtttatga agaaaaacaa
     1561 tctaacggac aatggctaaa atccattact tttaagctac caattataga agaaaatctc
     1621 aacatagatt tggacaatga tgaacaagtt gaatgtgtaa gtttattaga gaaacgtagt
     1681 taatcctcaa aaggttcccc aaaccttttg agtcccactg acgcatcacg ctgaggcggt
     1741 atcactgctt gtacgagttg aagcatcagc gaagtaaaag tagatgttca gccaatgcga
     1801 cgaggtgaga ccgaaggtcg ataaggtgtg ttctgggtat aggactcgta aagtaagtag
     1861 gaaatatgat gagatgatac agagagcctg aattggtcag gtgacgtgct tatttacatt
     1921 agcctgataa tgaaaatgga gagattattg atggttatat tggaattgta ccaaaatgat
     1981 tattctaaag atttagtagc atttgattcc atagaagatg ggaaagcctt tgtagctcaa
     2041 atcccgggat acactctgga aacagaagat ggttttgaag tggagtattt taatcctaaa
     2101 aacataccgg attatatgga aattattttt aacggaaata ttgttccttt atctaaattt
     2161 atgttcgatc ctgaggaaaa tgtaaacatt atttggaaag agatttcaaa tttatccctc
     2221 aaaaatgata gagtgatcga aggatattca aaaattgatg catatgtcgt taacaaccat
     2281 gaagttaaag cctatgtcga aacaagagaa acgaactatc gtaaagcaaa agacttctta
     2341 gaaagccgcg gatatgaaat cgacagaagc tttttcggaa gtgaagacgg tgaagcgatt
     2401 ctttacagaa aaaaagggat cgaagtttgg catttcttgt gtcacttaga cccaatgttt
     2461 gtagagattg aagatgtaga aggatatgtt aaagaagaag ttggagagat tcaatagtca
     2521 accaaagttc cttgtgagta tatacctttg ctagtaaaag agtcaaaacg ttataacgaa
     2581 ggggggtaag aaaacccttg agtgtaagtc tttttcttgt ttagagggaa agtattagag
     2641 tagccgctca taatttatac tagatttgat aactgatttg agacagattt tatttctata
     2701 aatattgtga aaatttttta ataccaaaga tttaaagtta ctgtgttaaa aatcctctcc
     2761 acttttaaac taatgtatta taaaagccag ttgacacaag tgttacacct gtgatagaat
     2821 taacttgagg tgatgaaaat ggcaaccgat aaaaatagaa taatgattag cttggatgat
     2881 aaaaatctag agaaacttga aaatttagta gaagatgcta gagatagaag gggaatgcga
     2941 ctaacaaagt cccaggttat tgaattactc ctaaataccg ttgattattt cgatgatatt
     3001 atgggggcta tttactcaaa aaaataagag caaaattgct attatttttt acaaattggt
     3061 gtaacactag tgatatagga gtgatgaaat ggttgtttat attagacaaa gtaaattacc
     3121 aagtgaggtt tcaattaata aatacaatgc tcaagtaggt gcctacttac aaggagaaga
     3181 agttatttta tatcaatctt tttctgaaat aaaagagtta ataagtgaag atatagttgt
     3241 agattatata atggagacta gagcattact aaaaatgatg ggcttaaacg ttccggttta
     3301 tgactatcct attgagctta aagagtttta tggtcgaaag atttatgctg gtattttagg
     3361 agagattgtg aatatacctg ataattgggg aaaatttatt aagcctaaag ctggttcaaa
     3421 agtctttact ggaagagttg ttaatggaac ccatgattta ataggtattg gtctaccttt
     3481 cgactatcct atatggatta gtgaggttgt agaattcata gctgaatggc gttgttttgt
     3541 gttagatggt cgcgtattag atgttcgacc ctatacaggt gattatcatg cacaatttga
     3601 tgcaagtgta attgatgaag cgatatcatg ttggaaagat gcgccaatag cttatggact
     3661 agatatcggt gttactcgcg atggcagaac acttgttgtt gaagtaaatg atggttatgc
     3721 attgggaaat tatggcctat ctcctttaaa atcaatcaat tttcatagag ctaggtggaa
     3781 agaaatggta aaaccctatt ttgaaaaaaa tgaaattttt aaaatccaac aggatgttat
     3841 tttctaaaat aaatatggta gataaccaat ataaaaagca tcaaaatgaa caaggaggaa
     3901 tctgatgctt ggagcaatta ttggagatat tgtcggttct gtttacgaat ggaacaatat
     3961 caaaacaaag gactttcctt tatttcggaa ggactgcttt tttacagatg acacggttat
     4021 gacctgtgct gttgcagaag caattatgaa tggtggacaa aaagacgatt tcattgacgc
     4081 gatgaagaaa tatggcagaa tgtatccgaa tgctgattac ggtgctcggt ttaatgcatg
     4141 gctaaacagc gataaccgtg agccttataa tagctttggg aatggatcag ctatgcgtat
     4201 ttctccatgt gcttggatca tggactgtgg tttttatgcg aaaactggta tgtggccatc
     4261 atctagagga cttacgagtc tttctgcaga ggtaactcat aatcatccag aaggtgtcaa
     4321 aggcgctatg gctacagctg atgctatctt tctatgtcgt ttttactttg gtggttattg
     4381 tagagagtac gagcaatcaa ttaacgacaa tcctacagag tgtaaaagac gaattaagga
     4441 ttatatagaa aaagaatacg attacaattt atctcaaact ttagatgaaa tccgtcctaa
     4501 ctatcgtttt aacgaaacat gtcaggaaac tgtccctcaa gctattatcg cctttcttga
     4561 aagtagagac ttcgaagatg cgataagaaa tgccatctca cttggtggcg acagtgatac
     4621 tctcgcagca atcacttgta acatagcaga ggcagcttac ggtattcctg attggatcaa
     4681 ggataaggcc tattcttact tggatgaacc cttaaaggat gtagttaggc gatgggaaaa
     4741 tagaataaaa gcgtattaat ctccagtacg tcagatttct cttttctgta ttttcattgt
     4801 ataataggat tacatttact tgcatacgac gaaatgtaaa catttctgtt taaaattaag
     4861 gataaaatca atgaaaaaag caatggtaat tatcaaccct acttctggtg gcgagaaggc
     4921 tttggattac aaagaaaagc tggagaataa agcaaaagaa tactttgaat atgttgaaac
     4981 caaaattacc gaaaaagcgc tggatgcaac acattttgct gaagaagctt ctcgtgagca
     5041 gtatgatgca gtggttgtgt ttggtggaga tggaactgtc aatgaagtca tttcaggtat
     5101 tgatgagaga gactacattc ctaagttagg gattatccca ggcggtacgg gtaacctcat
     5161 tacaaaactt ttggaaatca atcaagacat cgatggcgca attgacgaac tggattttga
     5221 tttaaccaat aagattgata tcggtaaagc aaatgacaac tattttggtt atatctttag
     5281 tatcggttct ctgcctgagg cgattcacaa tgttgaaata gaggacaaaa caaaattcgg
     5341 tattttaacc tatgctgtaa ataccatgaa gtctgtcatg acagatcagg tctttaacat
     5401 taaggttgag acagaaaatg gaaattatgt tggtgaagct agccatgttt tggtcctttt
     5461 gacaaattac ttcgctgata agaaaatctt tgaagaaaac aaggacggct atgccaacat
     5521 tttgattctg aaagatgcct ctatattctc caaattatcc gtcattcctg atttattaaa
     5581 aggggatgtt gtcgcaaatg ataatatcga gtatatcaaa gcgcgtaata ttaaaatctc
     5641 ttcagatagt gaattggagt cagatgttga cggagataaa tcagataacc tacctgtaga
     5701 aatcaaagtc ctagctcagc gagtagaagt attttcaaaa ccgaaagagg attagtatat
     5761 agagaaagcc ttttttaagg ctttttgtat actttaaaag atagttcctt taacaacgga
     5821 cattccttgc aaatagttta caaaaatagt atactggatt cattgagttt gaaaacgttt
     5881 gcgtaaaatt tgaatgaata ctttaggaga caaattgatg gaattgagtg ctatttacca
     5941 taggcctgag tcggagtatg cctatcttta taaggataag aaactccata ttcgaattcg
     6001 aactaagaaa ggggacattg aaagcatcaa cttgcactat ggggaccctt ttatctttat
     6061 ggaggagttt tatcaggata caaaagaaat ggtcaagata acttctggta ccttatttga
     6121 ccattggcag gttgaagtgt cagttgactt tgcacgtatc cagtatctct ttgagctcag
     6181 agatacagaa ggtcaaaata ttttgtatgg cgataaaggg tgtgtggaaa attctctaga
     6241 aaatcttcat gcaatcggga atggatttaa gttgccttat cttcatgaga ttgatgcctg
     6301 caaggttcct gactgggttt caaatacggt atggtatcag atatttcctg aaaggtttgc
     6361 caatggcaat gctctattaa acccagaagg gactttagac tgggattcat ctgtcacacc
     6421 taagagcgat gatttctttg gtggtgattt acaggggatt attgatcata tggattactt
     6481 gcaagacttg ggtattactg gactatatct ttgtcccatc tttgaatcta caagcaatca
     6541 caagtacaat acgacagatt actttgaaat tgaccgtcat tttggagaca aggagacctt
     6601 tcgggaactg gtggatcaag cgcatcatcg tggcatgaaa gtcatgctgg atgcggtatt
     6661 taatcatatt ggttcgcaat ctcttcaatg gaaaaatgtc gtcaaaaatg gtgaacagtc
     6721 tgcttataag gattggttcc atattcaaca attcccagtg acaactgaaa agctagttaa
     6781 taagagagac ttaccctatc atgtttttgg tttcgaggac tatatgccta agctaaatac
     6841 agccaatcca gaggtcaaga attatctttt aaaggttgcg acttattgga ttgaagagtt
     6901 taatatcgat gcttggcgtt tggatgtggc taatgagatt gaccatcagt tctggaagga
     6961 ttttcgtaag gcagttttag ctaaaaatcc tgatctttat atcctaggag aagtctggca
     7021 tacatctcag ccttggctaa atggagatga gttccatgcc gtcatgaatt atcctttatc
     7081 tgatagtatc aaggactatt tcttacgagg aattaagaag acagaccagt tcatcgatga
     7141 aatcaatgga gagtttatgt attacaagca gcagatttca gaggtcatgt ttaatctctt
     7201 ggattcacat gatacagagc gaatcctgtg gacggccaat gaagatgttc aactggttaa
     7261 atcagcctta gcctttctct ttttacaaaa aggaacaccg tgcatttatt acggaaccga
     7321 gctagccttg actggaggac cagatccaga ttgtcgtcgt tgtatgcctt gggaacgtgt
     7381 atcaagtgac aatgatatgc tgaactttat gaagaggctg attaaaattc ggaaatacgc
     7441 gtcagtaatc atttcgcatg gcaagtatag ccttcaagaa atcaaatctg atctagtagc
     7501 tctggaatgg aaatacgaag gacggatcct caaagcaata ttcaaccaat caacagaaga
     7561 ttatctttta gagaaagaag cagtagcact agcaagcaat tgccaagaat tggagaatca
     7621 gcttgtcatc tctccagatg gatttgtgat tttctaaaaa ctagttgatg aagattatgg
     7681 tacatttcat atcttatata gtataataag gctagttact aaacttgtaa aggagaactt
     7741 aaatgaattg tagaggacat gaaacaagac aaagaattgt tagagatttt gaagtttagc
     7801 ctaaagcaca tattaagctg ttagcaaatc aacaaaaaca tagtgatgca ggagcaacta
     7861 ttgaagatga atattatgta tttatcgctg agagtaaaat tgatggcaag aaggaagtta
     7921 ttcagtgttg catgggtgcg gcaagggatt ttttagaact aattaatcac aaagggctac
     7981 ctctttttaa tccgcttgta ggtgattctc atgtaaataa tagacaagaa tatgacaata
     8041 cagggagtgg aaatttacaa cctgaaaagt ggaatgaaac tgcaaagcag ctttataatg
     8101 ttataatgtg gttgattatt ttatggaatg ctaagccgga tacaccttta tttaatttta
     8161 aagacgaagt aattaagtat aaaacatatg agccttttga aagcagtata aaaagagtaa
     8221 atactactat aaagaatggt agtaaaggga aaactctgac tgagatgatt aatggctaca
     8281 gagcggataa cgatattaga gatgaaattt gtaactttaa tattctgaaa aataaaattc
     8341 gtgatatgaa agaccaacaa ggaaatacaa tggaatctta cttttagtta ttgttgaatt
     8401 ttgggtattc tataaaatat cctaattgag atttaaatag tagactatac aatatagtta
     8461 aaatatcagt aaaaacaaca ctttattgag gtattggata cgctttgcta atagcctaat
     8521 aatcacatgt ggagtgttgc tacaacgaaa aaggtgataa tccttgattt caagctattt
     8581 tataagcatt ttgtctttgt agataaaggc aattttgaca ataaaaatcc taaaaggtga
     8641 atcgttatag atgtatttgt agatatcgtt tgcgcatcga aaaaattaat acaataataa
     8701 atatttatgg ctctttaggt gacttttata gaagtaaagt ttaggataga aaaacaagaa
     8761 ataatgcacc atttttggtg cgttatgctt ttttatgcta taatggattt ataaaaataa
     8821 aggagtttgc catgattgga aagaacataa aatccttacg taaaacacat gacttaacac
     8881 aacacgaatt tgcacggatt ataggtattt cacgaaatag tctgagtcgt tatgaaaatg
     8941 gaacgagttc agtctctacc gaattaatag acatcatttg tcagaagttt aatgtatctt
     9001 atgtcgatat tgtaggagaa gataaaatgc tcaatcctgt tgaagattat gaattgactt
     9061 tgaaaattga aattgtgaaa gaaagaggtg ctaatctatt atctcgactc tatcgttatc
     9121 aagatagtca gggaattagc attgatgatg aatctaatcc ttggatttta atgagtgatg
     9181 atctatctga cttgattcag acaaatatct atttagtaga aaattttgat gaaatagaga
     9241 gatatagcgg ctatttggat ggaattgaac gtatgttaga gatatctgaa aagcggatgg
     9301 tagcttaatg gaaatccaag attatactga tagtgaattc aaacatgctt tagcaaggaa
     9361 tcttcgttca ctgacaagag gaaaaaagtc cagtaaacaa cctatagcga ttttgcttgg
     9421 aggtcaaagt ggtgccggta agactacaat tcatcgtatt aaacagaaag aatttcaagg
     9481 aaatattgtt atcatagatg gtgatagttt tcgttctcag catccacact atttagaact
     9541 gcagcaagaa tatggcaaag acagtgtaga atataccaaa gattttgtag gaaaaatggt
     9601 agagtcttta gtaacaaaat tgagtagttt gagatacaat cttttgatcg agggaacttt
     9661 acgaacagtt gatgttccaa agaaaacagc acaactcttg aaaaataagg gatatgaagt
     9721 acaattggcc ttaattgcga caaagcctga attgtcgtat ctaagtactc ttatccgtta
     9781 tgaagaactg tacattatca atccaaatca agcacgcgca actccaaaag aacatcatga
     9841 tttcattgta aatcatctag ttgataatac acgacaattg gaagaactag ctatttttga
     9901 aagaattcaa atttaccaac gagatagaag ttgtgtatat gattcaaaag aaaatacaac
     9961 ttcagcagca gatgttcttc aagagttact ctttggggag tggagtcagg tagagaagga
    10021 gatgttgagg gtaggggaaa agagacttaa tgaattactt gaaaaataaa caattgatat
    10081 ttttaggaga atagaaatga gagggtttaa taacaagata aagtctgttt atcaagaact
    10141 aacaaattcc aaagagaaat tcggtagctt tcacaagact ttaattcatt tgcatacacc
    10201 tgtttcttat gattacaagc tattttctaa ttggactgca acgaaatata gaaaaatt
//
LOCUS       DAVKAU010000062         9841 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVKAU010000062 DAVKAU010000000
VERSION     DAVKAU010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9841
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.062"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            229..324
                     /locus_tag="VWX48_001814"
                     /pseudo
     CDS             229..324
                     /locus_tag="VWX48_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(577..1197)
                     /locus_tag="VWX48_001815"
     CDS             complement(577..1197)
                     /locus_tag="VWX48_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9172389.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1197..1679)
                     /locus_tag="VWX48_001816"
     CDS             complement(1197..1679)
                     /locus_tag="VWX48_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU9172390.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMILQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1679..2521)
                     /locus_tag="VWX48_001817"
     CDS             complement(1679..2521)
                     /locus_tag="VWX48_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU9172391.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2616..3416)
                     /locus_tag="VWX48_001818"
     CDS             complement(2616..3416)
                     /locus_tag="VWX48_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU9172392.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3560..4939
                     /gene="glmU"
                     /locus_tag="VWX48_001819"
     CDS             3560..4939
                     /gene="glmU"
                     /locus_tag="VWX48_001819"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU9172393.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGSCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4949..5494
                     /locus_tag="VWX48_001820"
     CDS             4949..5494
                     /locus_tag="VWX48_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9172394.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5506..5820
                     /locus_tag="VWX48_001821"
     CDS             5506..5820
                     /locus_tag="VWX48_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU9172395.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5837..6529
                     /locus_tag="VWX48_001822"
     CDS             5837..6529
                     /locus_tag="VWX48_001822"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU9172396.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6606..7097
                     /gene="rocS"
                     /locus_tag="VWX48_001823"
     CDS             6606..7097
                     /gene="rocS"
                     /locus_tag="VWX48_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU9172397.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7195..7785
                     /locus_tag="VWX48_001824"
     CDS             7195..7785
                     /locus_tag="VWX48_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU9172398.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            7794..9557
                     /locus_tag="VWX48_001825"
     CDS             7794..9557
                     /locus_tag="VWX48_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU9172399.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMDRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9753..>9841
                     /locus_tag="VWX48_001826"
     CDS             9753..>9841
                     /locus_tag="VWX48_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9172400.1"
                     /translation="MWYNLFMAYSIDFRKKVLSYCERTGSITEA"
BASE COUNT         3047 a         1709 c         2095 g         2990 t
ORIGIN      
        1 agttcatgta cacctgatat gatgcgtttt ataattttaa agactttttg accagcctca
       61 tttttttaac ttgatactca gtgaaaagca aagattaaac taggaagcta gctgtaggct
      121 gctcaaagaa cagctttgag gttgcagata aaacttgtga ggtaaccaac atatataatg
      181 tgaagctgac gtggtttgaa tagattttag aagggtatga gtctggaagt tttaatggat
      241 aatgcaagat tccatagaat gggtaagcta gagttcttat gtgaagagtt tgggcataaa
      301 cttttacctt ttcctcccta ctcatcttag tatagaaaag tgaatctaaa atagtacata
      361 actgcttcta aaacattctt ataaattgat ttaaattctc aaatcatatt attcagttct
      421 tatttcattt tgctctacaa tcctgttgag aagacacgtg ttcatatcaa aaaggtattg
      481 gcaagttgca ataccttttt acaaggttct tttgtcttat ttttgtttca actgactata
      541 tctcctatgg ttctagttca gaaggctagg ctataattat gattgataag aagtatcatt
      601 ccaagtattg agagtgaatg tttcaaaatc atgggtttct ataatggtca ggctggcatt
      661 tgctagaccg ccatctttac gaagaagtgg ttctttatag cctaggagag tacgaagact
      721 ggcagtaaga ttggcgccgt gtccgacaat tagaatacgc tcagctggac tatcttttaa
      781 tgatttgata aattggatgg tccgctgagt tgtactatag agggattcgg ctccgaacat
      841 tcgagtgtca aattgagcaa gatttgaacg aaaagcctgg atttgttgcg ggtaaatagc
      901 ttccagggtt gcaattttca aaccttctaa cttcccaagt tgccattcac ggagattagg
      961 aacgatttct aaagaacagg gggtatggag ttgactttgg ataatctcag cagatttgac
     1021 cgctcgaggt aaatcacttg aataaatctg atcaaaagga atttccttga gatactggcc
     1081 aagtcgtttt agggtttcaa tggattcagg aagaagagga gaatcaccgc tagcaccttg
     1141 aaaacgacct tcttggttcc agagggtacg accgtggcgg acaaagtaga gtttcattac
     1201 ttgatgtcct ccaaaatatc tacaaagtct gcctttacaa agctagccaa gtcttgtggc
     1261 gcgacgataa tgctgtgtcc gacttcgcct gcagagacaa tcattcgatc caaatctaga
     1321 gcaattttat cgataaaaat gggataattg tgtttctgac gaattccgac aggattattg
     1381 gctccatgaa tgtaaccagt tgttttttct aagtcctttt gtagaatcat gctcactttt
     1441 ttattgccag aaattttagc tagtttcttt tcagacaagt gctgagtgat agggacaatt
     1501 ccgataatcg gtccggtctt gtctcccaaa agcgccaagg ttttgaaaat ctgatctcgt
     1561 tcataacctt gaggaagctc tccttctagg gcattgattt gaatcccctg atgagggatg
     1621 gctgctttag ataggatttg ttccaccaat gtttttttga ttttaacttt ttttgccatt
     1681 atttatattt atcctccaat tgactcatcc aaataccaag ccagattccc agcgcaaaga
     1741 agaaggcgat gatgacataa ccgacaagtg aaagtcctgt gtattggata ctttcagcgt
     1801 ttcctgcatt tggaattaag atcaaaaggg tacttgatag gacgataccg atgatgaaat
     1861 gatagacgcg tgagtggtag ttgtttaagg cataatccat caattttgaa aaaacgatga
     1921 gagttgcacc tgcaccaatt ccaatcggaa agaaggttcc caagagatca aaagttttaa
     1981 aaccagtcaa cataggagca tagagtccca aaatcaaaag taaattcgat gggctgaggc
     2041 caggaaccaa gacgccaagg gccaatagtg cgcctgctag gacgaagtta agaaagctgg
     2101 cgcttaaggt tccaacgaca aaatttaagg catatagtcc taatccagaa atgataaagg
     2161 ttgtccataa ccaagctaaa tcaatcttgt ctcggtcaga ttctcgagtt gattctttga
     2221 ggaggctagg aactgtaccg ataatagctc ccgcaaagct ccataataca aagacctgat
     2281 aattttcaag caggtattca atcgggtagg aaaataagcc gattcccaga agcataccga
     2341 tggcaactgg aataaagtac aaaacatttt ctttaaggtc tttaaaggga tgggccagaa
     2401 agccaatcat tcgttcatag attcctaaga ttgctgctag aacccctccg gaaattcccg
     2461 gtaggataaa tccaagagca attacaatcc ctttaataac gcgtgctaac catgagagca
     2521 tatatttcct ccaactattt ctatttcaaa aaatccttac tatattgtat cacaatcaga
     2581 cacaaaaaga aaaagcaaat gataaacaaa tgcttttaag gttttaaaaa aagctttcga
     2641 aaggtttctt ctttattttt taagggagag ataacgttga tatctaaatc gtggtcaaag
     2701 ccggcaattt ttcctttaga tgtgtattgg tgaatatcat aatctaaatc agttttagga
     2761 ctgctctcca aaaatcctga gtctgagccg taggacggaa tccaaacaga ggtaaacttg
     2821 cctgtatcaa tactgtgttc ttccatgaag tagacaccaa cgtagatgcc gatgttttta
     2881 gcacctagtg atgctagttt tgctcgaaag ttttcgacac cttcgttcat attagacata
     2941 gttttgtctt ccacgtcaag ccaatagtaa ctagggctgt aaggagaggc agcattgtag
     3001 aaaacttcgg cagccttttc catttcttgg acactttttc cagctacata agcgtagaca
     3061 gcaactggga cattccgctt ttgaagttca gtgatatgac tcttataggc cttgtctatt
     3121 ccattgataa atgaagcatc attttctttt gtcgtttgag caccactgtg aacacgaaca
     3181 atagcacctg aaatattttg tgagagggca tcgtagttga tttcctcagg acgctgccag
     3241 ccagagaggt caataatcgg tttgtctaag tgtttcaaag cctgtgcttc aatctgtgct
     3301 atattggatt ttgttttaaa cgattggctg tcattaagtg ggcgattgat gattaaaatg
     3361 aacatcataa tcccaaaaaa actaaataaa ataagtggat gaatttgttt tctcatatct
     3421 tataattcta ccctaaaaat caaaaaaaat caaaaaaatg ggttaaggaa gagactttag
     3481 agcatttttt cattcaagag tgcggaatga tttgaaatat ggtataataa aagggaattt
     3541 ctacagaaaa gagaagatta tgtcaaattt tgccattatt ttagcagcgg gtaaagggac
     3601 tcgcatgaaa tctgatttgc caaaagtttt gcacaaggtt gcgggtattt ctatgttgga
     3661 acatgttttc cgtagtgtgg gagctatcca acctgaaaag acagtaacag ttgtaggaca
     3721 caaggcagaa ttggttgagg aggtcttggc tggacagaca gaatttgtga ctcaatctga
     3781 acagttggga actggtcatg cagttatgat gacagagcct atcttagaag gtttgtcagg
     3841 acacaccttg gtcattgcag gagatactcc tttaatcact ggtgaaagct tgaaaaactt
     3901 gattgatttc catatcaatc ataaaaatgt ggccactatc ttgactgctg aaacggataa
     3961 tccttttggc tatggacgaa ttgttcgtaa tgacaatgct gaggttcttc gtattgttga
     4021 gcagaaggat gctacagatt ttgaaaagca aatcaaggaa atcaacactg gaacatacgt
     4081 ctttgacaac gagcgtttgt ttgaggcttt gaaaaatatc aataccaata acgctcaagg
     4141 cgaatactat attacagacg tcattggtat tttccgtgaa actggtgaaa aagttggcgc
     4201 ttatactttg aaagattttg atgaaagtct tggggtaaat gaccgtgtgg cgcttgcgac
     4261 agctgagtca gttatgcgtc gtcgcatcaa tcataaacac atggtcaacg gtgttagctt
     4321 tgtcaatcca gaagcaactt atatcgatat tgatgttgag attgcttcgg aagttcaaat
     4381 cgaagccaat gttaccttga aagggcaaac gaaaattggt gctgagactg ttttgacaaa
     4441 cggtacttat gtagtggaca gcactatcgg agcaggagcg gtcattacca attctatgat
     4501 tgaggaaagt agtgttgcag acggtgtgac agtcggtcct tatgctcaca ttcgtccaaa
     4561 ttcaagtctg ggtgcccaag ttcatattgg taactttgtt gaggtgaaag gatcttcaat
     4621 cggtgagaat accaaggctg gtcatttgac ttatatcgga agctgtgaag tgggaagcaa
     4681 cgttaatttc ggtgctggaa ctattacagt caactatgac ggcaaaaaca aatacaagac
     4741 agtcattgga gacaatgtct ttgttggttc aaattcaacc attattgcac cagtagaact
     4801 tggtgacaat tccctcgttg gtgctggttc aactattact aaagacgtgc cagcagatgc
     4861 tattgctatt ggtcgcggtc gtcagatcaa taaagacgaa tatgcaacac gtcttcctca
     4921 tcatcctaag aaccagtagg agcctatcat ggagtttgaa gaaaaaacgc ttagccgaaa
     4981 agaaatctat caaggaccaa tatttaaact ggtccaagat caggttgaat taccagaagg
     5041 caagggaact gcccaacggg atttgatttt ccacaatggg gctgtctgtg ttttagcagt
     5101 aacggatgaa caaaaactta tcttggtcaa gcagtaccgc aaagctatcg aggctgtctc
     5161 ttacgaaatt ccagccggaa aattggaagt aggagaaaac acagcccctg tggcagctgc
     5221 ccttcgtgaa ttagaggaag aaacagccta tacagggaaa ttagaactct tgtacgattt
     5281 ttattcagct attggctttt gtaatgagaa gttaaaacta tatttagcaa gcgatttgac
     5341 aaaagtggaa aatccgcgtc cgcaggatga ggatgaaacc ttggaagtcc ttgaagtgag
     5401 cttagaagaa gcgaaagaat taatccaatc aggtcatatc tgtgatgcca agacaattat
     5461 ggctgttcag tattgggagt tgcagaaaaa atagaggagg tcagtatggg taaatcttta
     5521 ttaacggatg aaatgattga aagagctaat agaggcgaaa aaatttcagg tcctcctttg
     5581 ctagatgata atgaggaaac taagatttta ccaacctctt cttcccgttt tggttatgcc
     5641 aatcctaagg atcatggttt tagccaggaa accttgaaga ttcaggtcga accatctatt
     5701 cataaaagcc gtcgcattga aaataccaag agaaatgtct tcaattctaa gttgaataaa
     5761 atcttattcg cggtcatctt tctcttgatt ttgcttgttt tagcaatgaa acttttgtaa
     5821 tagaaaagga attgaaatga aaataggaat tattgctgct atgccagaag aactggctta
     5881 tctggtccag catttagata atgcccagga gcaagttgtt ttggggaata cctatcatac
     5941 aggaaccatt gcttctcatg aagtcgttct tgtagaaagt ggaattggta aggtcatgtc
     6001 tgctatgagt gtggcgattt tggctgatca tttccaggtg gatgccctta ttaatacggg
     6061 ttcagctggg gcagtagcag aaggtatcgc tgttggagat gtcgtgattg ctgacaaatt
     6121 agcctatcat gacgtggatg tcacagcttt tggctatgct tatggacaaa tggcgcaaca
     6181 accgctttat ttcgaatcag acaaaacctt tgttgctcaa atccaagaga gtttatctca
     6241 attggaccaa aactggcatc ttggtttgat tgctacagga gatagttttg ttgcaggaaa
     6301 tgacaagata gaagcgatta agtcccattt cccagaagtt ttagccgtgg agatggaggg
     6361 ggcagctatt gctcaagcag cgcatgccct caatctccca gtcttagtca tccgagctat
     6421 gagtgacaat gccaaccatg aagcaaacat cttttttgat gagtttatta tcgaagctgg
     6481 acgtcgctct gcccaagtct tgttgacctt tttgaaggct ttagattaag cggaaatttg
     6541 acagtttttc tagcttatga taagatttaa gtaaagaaaa gctagaaaac gtttcagagg
     6601 atattatgag tattgaaatg accgtcagtg agattgcaga ggtcttagga ttatctcgcc
     6661 aagcaatcaa taaccgtgtc aaagaattac cagaagaaga cacagataaa aatgacaaag
     6721 gggtaacagt tgttaccaga agtggcttga ttaagctaga agaaatctat aaaaaaacga
     6781 tttttgaaga tgagcctgtc agtgaagatg tcaaacaacg tgaactgatg gagattctag
     6841 tggatgagaa gaatgcagaa attcttcgtc tttatgaaca attaaaagcc aaggatcgtc
     6901 agttatcaga aaaagacgag cagatgcgta tcaaagaccg tcagattgct gaaaaagaca
     6961 aacaattaga tcagcaacaa caattgaccc ttcaagccat gaaggatcaa gaaaatctta
     7021 agctagagct ggaccaagca aaagaagaag tccaatccac taaaaaaggc ttttttgctc
     7081 gtttatttgg aggataatca aggagctgtt taggttaaat gctaacctga tggcttcttt
     7141 tgtttgtgaa tagtatagtt gattagaaca gagacagtag aggagaggta cagaatggaa
     7201 cgattagaag attacattgc ttttgactta gaatttaatc agcacgaagg acaaacacac
     7261 ttgattcaag tatcggcagt gcgttttaga gatggtcggg aaatcgatgc ctatgattcc
     7321 tatgttcata ccagcgtccc tctaaaaagc tttatcaatg gtttgaccgg gattacagct
     7381 gagaccttaa aagatgctcc tccagttgag aaagtcttag aagaattcca agagtttgtg
     7441 ggttctttgc tgatgatagg ctacaatgct gctaaaagtg atttacctat tttagcagag
     7501 catggtttag actatagcca acagtacaag gtggatttgt atgatgaagc ttttgaacgt
     7561 cggagttcag atttacatgg tattgccaat ctcaaattgc aaactgttgc ctcatttctt
     7621 ggatttcaag gtcagtctca taatagttta gaggatgctc ggatgacggc gcgtgtttac
     7681 gaatccttct tagagtcgga tcaagctagg gaattgttag agacagaaag tagcttatca
     7741 aacaatcctt ttggtggctt ggacttgtct caattatttg actaggagtg cctatgaaac
     7801 ctgaaaaacc taaaaaattg ggtcttaaac agatttacct caatcttgat aaaatcctct
     7861 ttctattttt cttgattttt atgatagtgg agtatttgtg ggtaccattc aattcatggt
     7921 tggctagctt cttattagat cagacaggtt atctttttat ttcctataac aatgtcttag
     7981 ccatccttac tcattctcca ttgattagtc tagctttttt agccttgatt gtaattaacc
     8041 ttctggttgc ttattttcaa ataggactcc tctttattgg tgctcgtcat ctcctctata
     8101 atgaaaagcg aaggctaatt gagtatatcc gcaaggtttt ccatgaaagt tttggattta
     8161 tgaaaaagct aactggcgct aaagccttgt ttatcttttt ctatatagct atgctttttc
     8221 cttttatacg gaaaatgctg aagatttatt atcttaataa aatcgtcatt ccagagttta
     8281 tccaagctta tttagaagat aaatattgga tgtggtggct gagcatccta cttctatctc
     8341 ttatctttct ctatgtctct gtcagattga tgtttgccct tccgaagatt gtatatgatc
     8401 agctgactgt tcgagaagca gtgatgttta gcttggagaa aaccaagaag agagttactt
     8461 tttatgcttg gaatttattt tacatcttgc tcaaagcaca tttattattt tatcttcctt
     8521 tgattccttt attattggct caaactttgg tagatgatat cactcagaga gagtctctga
     8581 ttcttggtat tttgaatttt gtcgtgatta aaaatctcta ttatatggct ctgacttatt
     8641 ttttggttaa atttgtttca tttttgacag gaaaggagct ggatatgctt cctaggagag
     8701 aaaaagatca catcgtgcga tggggtgtca tgacttgtgc cagtcttttc tttgccttag
     8761 aaggttatat ttatctggag gctcccatgg ttcatctacc tcaacttatt tctcaccgag
     8821 gggtttccaa tgcaaatggg attcaaaata cagtagagtc cttggaaact acagcacaac
     8881 tcaaaccaga cttggtggag acggacgtgc aggaaacaaa agatgggcag tttgtcatga
     8941 tgcatgatgc taacttgaaa aatctagcag gtatcaataa aagtcctcaa gacttaaact
     9001 tggaggagct taaagggatt gatatttttg aaaatggcta ccagactaaa atttcaagct
     9061 ttgaagatta tctcagtcga gccaacgaac ttggtcaaaa attactaatt gaaattaaaa
     9121 ccagtaaaaa agatagtcca gacatgatgg accgcttttt agcccgttat gctgcaaagc
     9181 tcaagattta tggacatcaa atccagtctt tagactacca tgttgtcgaa aaagtaagac
     9241 agtatgatgc cgaactgcca gtttatttca tcatgcccta caattctgtc tttcctaaaa
     9301 caagagcgac aggatatact atggagtact caaccttgga tgaatatttt gtaagcaaac
     9361 tatggacaac ggatcagaaa ctttatgtct ggactgtcaa tgattcagaa gctatcagca
     9421 aatctcttca cttaggagta gatggagtga ttacagatga tttggaaaaa gttcagcggg
     9481 aaatagaagt agcccaagaa gatccagaat atacggattt gctcttgaaa aaagcattgg
     9541 aattctttga attttagtaa taaaaaagag gaacggttgt tcctcccatg ataggtaagt
     9601 attcttgtga atgcttgctt ttttgtggtt gcaatccgtt tacgagaatt gtttgtattg
     9661 ttcttgtttc aatttacttt atagtgcttt gaagttggaa tactacacta taacttctaa
     9721 aatatagtaa aatgaaccaa aaatagtaca caatgtggta taatcttttt atggcatatt
     9781 caatagattt tcgtaaaaaa gttctctctt attgtgagcg aacaggtagt ataacagaag
     9841 c
//
LOCUS       DAVKAU010000063         9102 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVKAU010000063 DAVKAU010000000
VERSION     DAVKAU010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.063"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            80..395
                     /locus_tag="VWX48_001827"
                     /pseudo
     CDS             80..395
                     /locus_tag="VWX48_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            610..726
                     /locus_tag="VWX48_001828"
     CDS             610..726
                     /locus_tag="VWX48_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9172401.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            719..970
                     /locus_tag="VWX48_001829"
     CDS             719..970
                     /locus_tag="VWX48_001829"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172402.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGLSVSEFEPFCVEKSPI"
     gene            1014..1292
                     /locus_tag="VWX48_001830"
                     /pseudo
     CDS             1014..1292
                     /locus_tag="VWX48_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1429..2397)
                     /locus_tag="VWX48_001831"
     CDS             complement(1429..2397)
                     /locus_tag="VWX48_001831"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9172403.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(2542..3084)
                     /locus_tag="VWX48_001832"
     CDS             complement(2542..3084)
                     /locus_tag="VWX48_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU9172404.1"
                     /translation="MDQLLGVLFPDSTFLNAFESAIVAPLVEEPLKLLPLVFVLALIP
                     VRKLKSLFLLGIASGLGFQMIEDIGYIRTDLPEGFDFTISRILERIISGIASHWTFSG
                     LAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAIPVVTAI
                     ALYGFYHAYCFVEKHNELMT"
     gene            complement(3088..3372)
                     /locus_tag="VWX48_001833"
     CDS             complement(3088..3372)
                     /locus_tag="VWX48_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172405.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFLALFYM
                     IPALYFLFHIGKKWELPKKVLILSLLGAICSFTSLLLFGIYNHRRKSSKV"
     gene            complement(3397..3894)
                     /locus_tag="VWX48_001834"
     CDS             complement(3397..3894)
                     /locus_tag="VWX48_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU9172406.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(3967..5328)
                     /gene="radA"
                     /locus_tag="VWX48_001835"
     CDS             complement(3967..5328)
                     /gene="radA"
                     /locus_tag="VWX48_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU9172407.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(5342..5857)
                     /locus_tag="VWX48_001836"
     CDS             complement(5342..5857)
                     /locus_tag="VWX48_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9172408.1"
                     /translation="MKIIFVRHGEPDYRELEERFYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(5859..6302)
                     /locus_tag="VWX48_001837"
     CDS             complement(5859..6302)
                     /locus_tag="VWX48_001837"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU9172409.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(6362..6455)
                     /gene="ffs"
                     /locus_tag="VWX48_001838"
     ncRNA           complement(6362..6455)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VWX48_001838"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(6488..6955)
                     /locus_tag="VWX48_001839"
     CDS             complement(6488..6955)
                     /locus_tag="VWX48_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU9172410.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(7156..8442)
                     /locus_tag="VWX48_001840"
     CDS             complement(7156..8442)
                     /locus_tag="VWX48_001840"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU9172411.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(8673..8909)
                     /locus_tag="VWX48_001841"
     CDS             complement(8673..8909)
                     /locus_tag="VWX48_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU9172412.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         2911 a         2171 c         1519 g         2501 t
ORIGIN      
        1 ttcacatctt atttcaactc actatagaag gaggaatagg aggattctca gacatccggg
       61 catcagccca actaatgatt tgattgctaa gaaaatattc agcaatccag aaatcacttg
      121 tcaatttatt cgcgatatgc tggacttgcc agcaaaaaat gtgaccattt tggagggaag
      181 cgatattcac gtattacttc tccatgcctt actcagtgca ggatttttat accagtatag
      241 acgtcttggc ggagttggat aacggtactc aagtaattat tgagattcaa gtccatcatc
      301 agaatttttt catcaatcac ttgtggactt acctgtgcag tcaggttaat caaaatcttg
      361 aaaaaattcg tcagcgagaa ggtgatactc actagagcta caaacacatc gctcctgttt
      421 acgccattgc tatcgtggat agtaattatt tctcagatga cctggctttt catagcttta
      481 gtatgcgcga agacacaaca ggtgaggtat tggcgattac caacaatgga caggaaaacc
      541 atctggttaa gatggcattc ttggaattaa aaaatacaga gaaaccagca aggacgaggt
      601 tcgcaagcca tggttggagt ttttcggcaa caagcccttt acccagcaac cgcaacgagc
      661 cattacccaa gcaaatcaac tgctggacta caagagctgg tccgaggagg acaggaaaat
      721 gtttagtcaa ctacatatgc gagaagaaca agtcttgtta gcacaggact atgccttgga
      781 aactgctagg gctgaaggcc ttgaacaagg actagagcgt gggaaagttg aaggaagggc
      841 agaaaggaaa ctttttgcct tcctagacat agtacgccaa ggtcttctga cttctgaggt
      901 tgccagccag caattaggtc tgtcagtatc tgaatttgag ccattttgtg tagaaaaaag
      961 tcccatataa cctataatga aaagcgacaa aacaactcat tagaaagaat catatggaac
     1021 aattacattt tatcacaaaa ttactagaca ttaaagaccc taatgtccag attttaaaca
     1081 tcatcaataa ggatacacac aaggaaatca tcgccaaact ggactacgac gccccatctt
     1141 gccctgagtg cggaaaccaa ttgaagaaat atgactttca aaaaccttct aaaattcctt
     1201 atcttgaaac gactggtata cctactagaa ttctccttag aaagcgtcga ttcaagtgct
     1261 atcactgttc aaaaatgatg gtcgctgaaa cttatgatga cgtacagtca tatttcttct
     1321 ctttttatta tatcacagtt ttaaatctag ctttactaga ttcaccgcta ctatctattt
     1381 attcggaaaa aagacgaaaa aacctgagaa tcatctcagg cttggtcatt aaattttttt
     1441 ctcaatatcg aaaagtggag aaagtggtcg tttttcatga atacgtacga tagcatcccc
     1501 taggagatga gcgattgaaa tctgctcaat cttatcaatc aaacgctctt ctggcagata
     1561 gatggtatcc aaaacaacca atttcttaat agctgatttt tggatattgt ccgtagcagg
     1621 accagaaaga actgggtgcg tacagcttgc atagacttca acagcaccag cttccgcaag
     1681 agcatctgcc gcatgacaaa tcgttccagc ggtatcaatc atatcatcaa tcaagataca
     1741 agtcttgcct tcaaccttac cgatgatgtt cataacttca ctagtattca tcttatcaac
     1801 gctacgacgt ttatcaataa tagcgataga tgttttcaaa aattctgcca acttacgagc
     1861 acgagtcacc cctccatggt ccgggctgac aaccacatag tcagaaccaa ccataccacg
     1921 acgctcaaaa taatctgcaa tcagaggagc acccatcaaa tgatccacag gaatatcaaa
     1981 gaatccttga atttgcgcag catgcaagtc gatggtcaat aaacgatcca ctccagctac
     2041 ttcaagcata tttgcgacaa gttttgaagt gattggctca cgcgctctcg cctttctatc
     2101 ctgacgtgca tacccatagt aaggcatgac aacattgaca gattctgcac tcgcacgctt
     2161 caaagcatct accataatca aaatttcaag cagattgtca tttacaggcg aactagttga
     2221 ttgtaagata aagacgtgtt tcccacggat tgattcttca atgttgacct gaatctctcc
     2281 atctgaaaat tggcgaacac ttgatttccc caactctatc ccaatctcct gcgccacacg
     2341 ttctgccaat tctttattag aagaaagggc aaacagcttt aaatcagaaa aagacatgat
     2401 ttcctccggt atatatgtat aacttgtgtt tttcacaaga ttttccatct accattgtag
     2461 cgctttttgc actatttttc aatcaaaaat aaaagaaggg caccatattt gtacccttgc
     2521 atcattcttt tgaaaaatat tctaggtcat caactcattg tgtttctcaa caaagcaata
     2581 agcatgataa aaaccataga gagcaatagc cgtaaccact ggaatcgcta aaggcaactc
     2641 tgtttccaac tccacaaaag gagagttaaa caagaagtga gttcccaagg ctaaacctag
     2701 aaaaataagg ccctgtttct tgccaacctt ctgtccttta taggctctgt aaagcaagta
     2761 aacacctact acagctagac ctgaaaaagt ccagtgagag gcaattcctg agatgatacg
     2821 ctctaaaatt cgcgaaatag taaagtcaaa gccctctggc aaatccgtac gaatataacc
     2881 aatatcctca atcatttgga atcccaaacc ggaagcaatt ccaagtaaaa acaaagattt
     2941 taattttcgc acaggaatca aagccaaaac aaaaacaagt ggcaataatt tcaagggttc
     3001 ttctaccaaa ggagccacaa tagcactttc aaaggcattt aaaaatgtac tatctgggaa
     3061 aagaaccccc agtaactggt cgatttttta taccttagat gactttcgtc tgtgattata
     3121 gattccaaat agtaagagag aagtaaagga acagattgct cccaataaag acagaatcaa
     3181 aaccttcttt ggcaattccc attttttccc aatatggaag agaaaataaa gagccggaat
     3241 catgtaaaag agagctagaa agatagaaac tcccattagt ccatattccg cacctgacct
     3301 cgaaccgtcc gtatagtaga tggtttcata ctgtaaacca atacatagca ataaaatact
     3361 gcttttcttc atacactttc tttctaaatg aagtatttat aattctacga ctgtcatact
     3421 tcctgtatca acattgtaaa tagcaccaga gataatgaca tcgtctggta ttaggggaga
     3481 ctcgataagc agttgcatat cctcgcgtac actctcttct atatcttgga agggcaagaa
     3541 gtcctggtct gacacatcta cacctaattc ctcttttaaa tactcctgaa aaggttcatt
     3601 ttcaaaggtc tgagcaccac agtctgtatg gtgcaatacc acaatctctc ttgtccccat
     3661 ttgttgctgg gaaataacta gcgaacgaat catgtcttca gtcactcgac cacctgcatt
     3721 ccgcaagata tgagcatccc caagtgccaa gcccagagct tgcgcaacgt gcagacgaga
     3781 gtccatacag gtcacaatag ctactcttgt tttgggttta agtggcagat ttaactgccc
     3841 atgtagggca acataagcct gattagcttg cataaactgt tcaaaatacg acacgattcc
     3901 ctccttgaaa atttgatagt caaatatttc tcctatctta tcatttttaa gagaatttgt
     3961 cacggattat gcaaagacct ttttcaaaac ttcctgaatc gttgtcacgc caatgacctg
     4021 aatttcctta ggcagagtga ttcctgtcaa ggaattctta ggtacataaa tcttagtaaa
     4081 gcccagttta gcagcttcgt tgatgcgttg ctcaatacga ttcacgcgcc gaatctctcc
     4141 tgtcaagccc agttctccga caaaacattc ctgaggatta gttggcttgt ctttgtagct
     4201 cgaagcaata gcaactgcaa cagccaagtc aatggcaggt tcatccaatt taacaccacc
     4261 agcagatttg agataggcat cctgattttg caagagaagc cctgcccgtt tttccaaaac
     4321 agccataatc aagctagcac ggttaaaatc aagtcctgtc gtagtacgct tggcatttcc
     4381 aaacatggtc ggtgttacca aagcctgaac ctccgccaaa atcggacgcg tcccttccat
     4441 ggttacaacg atggaggaac cagtcgcccc atccaaacgc tcttctagga aaacttgact
     4501 cggattgagt acctcaacca agccgcccga ctgcatctca aaaatcccaa tctcattagt
     4561 ggaaccaaaa cgatttttga ccgctctcaa aatacgaaag gtgtggtgac gctccccttc
     4621 aaagtaaagc accgtatcca ccatatgctc caacatacga ggcccagcca aggttccttc
     4681 tttggtcaca tgacctacga taaagatggc aatgttattg gtcttggcca actgcatgag
     4741 ttcagcggtc acttcacgca cctgagaaac agacccctgc acccctgaaa tctcaggaga
     4801 catgatggtc tggatggaat caataatgag aaagtctggc tggatacgct ccacttctgc
     4861 acgaacactc tgcatattgg tctctgcata gagataaaac tcactatcaa tatcacctaa
     4921 gcgctctgca cgtagtttaa tctgctgggc agactcctcc ccactgacat agagaactgt
     4981 ccccacttgg gacaactggg ttgagacttg taggagaaga gttgatttcc caatcccagg
     5041 atccccaccg atgaggacga gacttcctgg tacaactccg cctccaagca cacggttgaa
     5101 ttcctccatc tccgtcttgg ttcgattgac attgatggaa gtcacctcag ctagtttcat
     5161 gggcttggtt ttctcacctg tcaaggacac acgcgcattc ttgacctcgg caacctcaac
     5221 ctcttccaca aaagaagacc aagacccaca gttggggcaa cgtcccagat atttagggga
     5281 attataccca caattttgac atacaaatgt cgcttttttc tttgcgatga caaacctctt
     5341 tctatatctc taactcacac tcaatcactt ggcaaaaatc aatcttctca tttggcacaa
     5401 actggcgcat gagcattcga tgagcaacaa ctaccacagt ctgatgttct cgatacttag
     5461 acatacattc tagaaaccga gacttcattt ccgtagctgt ctcatattga ataggactat
     5521 taggaagcaa ctcccccttg ttttctaaaa acagtcttct agctgtttca aagttttcta
     5581 ttcctgtttt atagacctgc cattcatgta ataaaggctc tactcttaaa ggaagacccg
     5641 tagcacagac cacatacgaa gccgtttcta aagctcttgt gactgcagaa gatacgatta
     5701 tttcagctga cgagagtaaa ggagttttgc tcaatttctg gacttgctgc cgtcccatct
     5761 cagacaaggg tgccaaatct atcccaaatc ctatataaaa acgctcctct aactcacggt
     5821 aatctggctc cccatgacgt acaaagataa tcttcattct agtgccctgt cgatccaaat
     5881 ccaccagttc gaacgccatc agccgcatct ccatctgcaa ttaagaaagt agcaaaaaca
     5941 gcctggacaa tacgctcccc aacttcaaga acaacctctt ggtctgtgat attcttcatc
     6001 tgcgcaaaaa tatgcccttc atttccagga tttccataat aatccccatc aatgacccca
     6061 actgagttaa ttaaaaccaa gcccttctta cgaggatttg aagaacgatc atagaggtag
     6121 agaacctcag tcggctgcat ataagcctta acccctgtcg gaaccaagac aatctctcct
     6181 ggcgcaacaa ctgtacgcac agcaaccttt aagtcgtaac cagccgcatg cgctgtctca
     6241 cgcttgggca ataaattttc atctgtaaaa ctcgaaacca attcaaaacc acgaattttc
     6301 ataattttct cttttctatt atcatttatt ctagattatt ctatcttatt tattcggaaa
     6361 aagcacgaaa aaagagcaca caattcaaat cgcttagggc tgctggattc ctcccctgac
     6421 ccgcttcacg cagaactgtt gctccactat ttattatatc acattcctat tcattttaaa
     6481 agcaaaatta ttttttccgt ctatttctaa aaaaatcctg catgatagct gcgcattcat
     6541 cttccaaaat tcctatttca acctccacac gatgattgag acgctcatct gtcaagatat
     6601 cgtacaaact cccagcagcg ccaaatttct ggtttttagc cccatagacc acatttggaa
     6661 tgcgggcaag cccaatcgcc ccactacaca tgacacaagg ttcaatggtc acaaaaagtg
     6721 tgcaatccag caagcgccag ctctcctcac tcaagttcgc atcctctata gccataattt
     6781 ccgcatgcat aaccgctcgc tgtaattcct cacgcgcatt atgcccacga ccaatgattt
     6841 ccccatcttt gacaatcaca caaccaattg gaatttcatc gtgttcaaga gcaatctcag
     6901 cctctctcaa agcctccctc ataaagactt ctttttcttc aagcgtataa tacatctctt
     6961 ttctcttttc ctacttatcg attttattat tatatcatga atcccaacac aaaaaaagcc
     7021 accgaatgcg gtgactctat agggagatta ttatgaaaaa gaaaagttta ggatatttgt
     7081 tacaacaagt taggaggtct tcttgtaact gtctatagta tacccgacct atcttaaaca
     7141 aatcttaaaa atctcttagg accaaacact ttctaaaata tttgtttgtt cacgaccagg
     7201 acctactgag aaagtagaaa tacgaacgcc aaccaattca ctcacacgac gaacatagtt
     7261 acgcgcattc tcaggaagat cttccaaatt gcgaactccg gtaatatctt ctgaccaacc
     7321 tggcaactct tcatagatag gcttgcaacg tttcaattgc tcaagactag ctggatagta
     7381 gtcaatacgt tgaccgtcaa gatcataggc cacacagatt ttcacagtat ccaaaccgct
     7441 caaaacatca atagagttca aagaaaggtt agtaatacca gaaacacgac ggctatgacg
     7501 catcacaact gagtcaaacc aacctacacg acgtggacga ccagttgttg taccatactc
     7561 atgacccact tcacggatac gttctcccac ttcatcaaac aactcagttg ggaaaggacc
     7621 atctcctaca cgactcgtat aagctttaca tacacctaca accttgtcaa tcttgcttgg
     7681 accgacacca gaaccaattg tcacaccacc agctacaggg tttgatgacg taacaaatgg
     7741 ataagtacct tggtcgatat ctagcataac accttgtgca ccttcaaaaa gcacacgttt
     7801 gccattatca agcgcatcat tcaagataac agatgtatct atcacgtatt tcttgatttg
     7861 ttgaccatat tcgtaatatt cttcaaaaat atcatcgaaa acaatcgctt tactgtcata
     7921 caatttttca aaaagacgat tcttttcagc aaggttacgt tctaaacgct cacggaaaat
     7981 atctttatct aaaagatctg caatacgaat tccaacacga gcagccttgt ccatataagc
     8041 tggaccaatt cccttaattg tcgtaccaat cttattgtcg cccttagctt cttcttgcaa
     8101 gcgatccaac tcgatatgat aaggcaaaat aacatgcgca cgatcagaaa tacgcaagtt
     8161 atcagttgtt acaccttcct catgaagata gctcaactct tttacaagag atttaggatt
     8221 tacaaccata ccattcccaa tgacagatat tttttcaggg aagaaaatcc cagatggaat
     8281 caagtgcaac ttaaatttct taccgtcaat cacaatcgtg tgaccagcat tatcaccacc
     8341 ttggtaacgt gcaatcactt ctgcattcgc tgaaaggaag tctgtaatct tccctttacc
     8401 ttcatcaccc cattgggtac ctacaacaac aactgaagtc ataatcttgt ctgagccctc
     8461 aggctcttcc tttctcacat acatggcagg actctcacct gcaattatat cttacaattt
     8521 attataataa aaaatcgcct ttttatcaag aagaaacaat agaaagattt gctatttcca
     8581 actattaaaa aatgatttag aaaaattact agctatttac tatcatcttt ccataaaaga
     8641 gtaaattagt tcggaaattt actaaaatta cctcaacaag aaataaaacc ccgattcatt
     8701 accaattttt caagatacaa acgataagca acacgataat ggtaaacgat aaaatcccta
     8761 cgacaaccaa tgccatatct cactaaataa taaattaaaa atttaaaatg aacatgttcc
     8821 cagtcaaaat tatcaccaaa tgtaggacca tactcttctt caatactatc atagaaatta
     8881 gccatctgct cataaatttt ttgtaacata atcaaatact ccttttcttt tttataaact
     8941 tattctaaca aaaaatttta cacattcact atcaattcct gaattgttaa aataccagcc
     9001 tcaacaagat aaaaatagga aaagttgaca aaatagaaac aaatttgtta cctaaatttc
     9061 aaacaattaa agttctaaaa agaccgcctt aaaacttttg gg
//
LOCUS       DAVKAU010000064         8753 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVKAU010000064 DAVKAU010000000
VERSION     DAVKAU010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8753)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8753)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8753
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.064"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..333
                     /locus_tag="VWX48_001842"
     CDS             <1..333
                     /locus_tag="VWX48_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9172413.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
     gene            500..1198
                     /locus_tag="VWX48_001843"
     CDS             500..1198
                     /locus_tag="VWX48_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9172414.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1195..2247
                     /locus_tag="VWX48_001844"
     CDS             1195..2247
                     /locus_tag="VWX48_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9172415.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2442..3053
                     /gene="rpsD"
                     /locus_tag="VWX48_001845"
     CDS             2442..3053
                     /gene="rpsD"
                     /locus_tag="VWX48_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU9172416.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(3147..4313)
                     /locus_tag="VWX48_001846"
     CDS             complement(3147..4313)
                     /locus_tag="VWX48_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU9172417.1"
                     /translation="MQIKQITKKDGSIVYRANVYLGVDKVTGKDVKTSITGRTKKEVK
                     QKTKEAEIAFLQNGSTRFQASNITTYKELASLWWESYKHTVKPNTQLNVRRLLDNHIL
                     PLFGSYKLDKLTTPLIQNIVNKLADKTNKGEEGAFLYYDSLHALNKRILQYGVVMQAI
                     PFNSAREVILPRNTQKAKREKVKHFDNDELKSFLKYLDTLDLSRYRYYYEITLYKFLL
                     ATGCRINEALALSWSDIDLDNAIVHITKTLNYNQELNSPKSKSSYRDIDIDQATVSML
                     KQYKHRQVQEAWQLGRSETVVFSDFINEYPNNRTLQTRLRTHFKRADVPNIDFHDFRH
                     THASLLLNSGIPYKELQHRLGHSQLSMTMDIYSHLSKENAKKAVSFYETALKSL"
     gene            4582..4764
                     /locus_tag="VWX48_001847"
     CDS             4582..4764
                     /locus_tag="VWX48_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172418.1"
                     /translation="MDPDKRQKIFSQCKKEGDSLEQRKQEILEKYANKQDKPKSRKND
                     SKGSESHKRKTKSKEF"
     gene            4814..5674
                     /locus_tag="VWX48_001848"
     CDS             4814..5674
                     /locus_tag="VWX48_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEU9172419.1"
                     /translation="MTTNLVKQKENLEAYIRSTGYNTRGMNVENNHVLIEKPILDSYE
                     DEHQRKELVDLVNVIETRTRGGKYEVTDFESDSLQEISENFVERTESDKKKTISVDYL
                     VKLFSGKLDFSQEQLDDGQYNLTDFLGKKIIKLKRRTRNREIGKILQTAKVQTATSLD
                     DLKSIVSLINPERNVSIVISQSLFSVLEKMKDTSGNYLLKVDKETGTSETFFVDNFLI
                     VDDTTLGNEGDKKGFIGDLENFVTLFDRKKDTLSWVNANDYFRKRLILHTRFDVKKVE
                     EDCGYFIQWN"
     gene            5684..6232
                     /locus_tag="VWX48_001849"
     CDS             5684..6232
                     /locus_tag="VWX48_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172420.1"
                     /translation="MDINQVFDTLDDLDNKKSKIYSAREQLSEKRKSLLGIQTVSFEN
                     INSFLSNNLESLEKLEKMEKAINSLQEKYNSDFSEAKAVIFEYIFKETKQRMETKKIY
                     KQYRKKLRRILDAYDEIQELKKDVEEIHTGVVREISQKHSLSLYRTEVSPLTVLPFLN
                     PDISGWMDFSKEYRDIKEYLEK"
     gene            6610..7020
                     /locus_tag="VWX48_001850"
     CDS             6610..7020
                     /locus_tag="VWX48_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEU9172421.1"
                     /translation="MYELSNRDLDGIDIELGRYRTLASKIYLRRQELIHNKKHSTEDY
                     TGGKGKTVYSPTEATIIRIEEDQTLRYLEGFKLIVDTLMENLIDTDLVIFKMRFLEAG
                     VTWEDVAEKLNKTTRYINSRRKVIAKRFIELKGY"
     gene            7396..8589
                     /locus_tag="VWX48_001851"
     CDS             7396..8589
                     /locus_tag="VWX48_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172422.1"
                     /translation="MTAEIGILNKNGVVLAADSAVTLSDGINSKVFNSARKLFTLSRV
                     HSVGIMIYGDASFMGVPWEVIISEYKKSIGNEVLADTAMYINNFVDFLLQFMLIQSND
                     ALVNYIIRQTRSYLKIIHESTQEIADHRSDQGDVITLEIFKNILWEVIEEYSNDISKS
                     ISETEFEYLDGELDLIREQLDEYFNNNEYSDEQLNFLSKTIYKAMLVGFDRNSVTGLV
                     IAGYGVEEIFPSLRQIELSGVFAKRLVWRVITEKEISQNVACHIIPFAQSEMVDTIMN
                     GIDPMLNAFIGQQINEILESNNISDAQEELFETIARVQQQYYINPIFELIGMQPIDEM
                     ASTAKTFIELTSFKRKIVNTLETVGGPVDVLAISKGEGPIWIERKHYFNIENNIDYKI
                     RKGDI"
     gene            8589..>8753
                     /locus_tag="VWX48_001852"
     CDS             8589..>8753
                     /locus_tag="VWX48_001852"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172423.1"
                     /translation="MYAANFSKEKYGFLDKKIYQNLSQSNVGKNFLEVYKEIDTKPKN
                     QISKTLVDKSI"
BASE COUNT         2989 a         1343 c         1795 g         2626 t
ORIGIN      
        1 ataaatgtta aagaaacatc agacacagca aatggttcat tatcaccttc taactctggt
       61 tctggcgtga ctccgatgaa tcacaatcat gctacaggta ctacagatag catgcctgct
      121 gacaccatga caagttctac caacacgatg gcaggtgaaa acatggctgc ttctgctaac
      181 aagatgtctg atacgatgat gtcagaggat aaagctatgc taccaaatac tggtgagact
      241 caaacatcaa tggcaagtat tggtttcctt gggcttgcgc ttgcaggttt actcggtggt
      301 ctaggtttga aaaacaaaaa agaagaaaac taatcagcta aggaaataaa tgatggatag
      361 tgggctgact aagattagtt taacaactca atcagcaatc aggactttct ttcaatagca
      421 gattaaaatc atcgtaaaac aataaaaata gtgttatact taaagcagta tagcactgtt
      481 tttatcaaag gagagacaga tgggaaagac aattttactc gttgacgacg aggtagaaat
      541 cacagatatt catcagagat acttaattca ggcaggttat caggtcttgg tagcccatga
      601 tggactggaa gcgctagagc tgttcaagaa aaaaccgatt gatttgatta tcacagatgt
      661 catgatgcct cggatggatg gttatgattt aatcagtgag gttcaatact tatcaccaga
      721 gcagcctttc ctatttatta ctgctaagac cagtgaacag gacaagattt acggcctgag
      781 cttgggagca gatgatttta ttgctaagcc ttttagccca cgtgagctag ttttgcgtgt
      841 ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca gagctgattt cccttggcaa
      901 tctaaaaatg aatcatagta gtcatgaagt tcaaatagga gaagaaatgc tggatttaac
      961 tgttaaatca tttgaattgc tgtggatttt agctagcaat ccagagcgag ttttctccaa
     1021 gacagacctc tatgaaaaga tctggaaaga agactacgtg gatgacacca ataccttgaa
     1081 tgtgcatatc catgctcttc gacaggagct ggcaaaatat agtagtgacc aaacgcccac
     1141 tattaagaca gtttgggggt tgggatataa gatagagaaa ccgagaggac aaacatgaaa
     1201 ctaaaaagtt atattttggt tggatatatt atttcaaccc tcttaaccat tttggttgtt
     1261 ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga tttacttttt gcttgggatg
     1321 accatcgttg ccagccttgt cggtgctggg attagtctct ttctcctatt gccagtcttt
     1381 acgtcgttgg gcaaactcaa ggagcatgcc aagcgggtag cggccaagga ttttccttca
     1441 aatttggagg ttcaaggtcc tgtagaattt cagcaattag ggcaaacttt taatgagatg
     1501 tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa gcgaacgaga aaagggcttg
     1561 atgattgccc agttgtcgca tgatattaag acccctatca cttcgatcca agcgacggta
     1621 gaagggattt tggatgggat tatcaaggag tcggagcaag ctcattatct agcaaccatt
     1681 ggacgccaga cggagaggct caataaactg gttgaggagt tgaatttttt gaccctaaac
     1741 acagctagaa atcaggtgga aactaccagt aaagacagta tttttctgga caagctctta
     1801 attgagtgca tgagtgaatt tcagtttttg attgagcagg agagaagaga tgtccacttg
     1861 caggtaatcc cagagtctgc ccggattgag ggagattatg ctaagctttc tcgtatcttg
     1921 gtgaatctgg tcgataacgc ttttaaatat tctgctccag gaaccaagct ggaagtggtg
     1981 gctaagctgg agaaggacca gctttcaatc agtgtgaccg atgaagggca gggtattgcc
     2041 ccagaggatt tggaaaatat tttcaaacgc ctttatcgtg tcgaaacttc gcgtaacatg
     2101 aagacaggtg gtcatggatt aggacttgcg attgcgcgtg aattggccca tcaattgggt
     2161 ggggaaatca cagtcagcag ccagtacggt ctaggaagta cctttaccct cgttctcaac
     2221 ctctctggta gtgaaaataa agcctaaaac ccctttacaa atccagctat tcatggtaga
     2281 atagattttg tgtgaaatat cagcaggaaa gcatgaagct cgtcaacagg tgtcttatga
     2341 caagtaacct tggctgttta ggcgaagggc atctgcacga atcagggctt tctaagtgac
     2401 tatttccacc gaaatattat ttatatcagg aggacattca tatgtcacgt tatacaggac
     2461 catcttggaa acaagctcgt cgccttggcc tttcacttac aggtacaggt aaagaattgg
     2521 cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa ccgttctaaa ttgtcagaat
     2581 acggtttgca attggctgaa aaacaaaaac ttcgtttcac ttacggtgta ggtgaaaaac
     2641 aattccgtaa cttgttcgta caagctacaa aaatcaaagg cggaatccta ggtttcaact
     2701 ttatgcttct tttggaacgt cgtttggata acgttgttta ccgtcttggt ctcgcgacta
     2761 ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat ccttgttgac gggaaacgcg
     2821 ttgatatccc atcataccgc gtaactccag gtcaagtgat ctcagttcgt gaaaaatcat
     2881 tgaaagttcc agcaatcctt gaagcagtag aagctactct tggacgtcca gcattcgtat
     2941 cattcgacgc tgaaaaattg gaaggttcat tgactcgctt gccagaacgc gacgaaatca
     3001 acccagaaat caacgaagca cttgtcgttg aattctacaa caaaatgctt taattttaag
     3061 aaatatctta cagaaagcct acaacagtgg gctttttgct ttgtcttaaa atgttgattt
     3121 ctgggtttgt tcagttattt gttcagttat aaacttttta gtgcagtttc atagaacgaa
     3181 actgcttttt ttgcattctc ttttgagagg tgactgtata tatccatggt catagataat
     3241 tgggaatgtc ctagacggtg ctgaagttcc ttgtaaggta ttccagagtt aagcaagaga
     3301 ctagcgtgag tatggcgaaa atcatgaaaa tcaatgttag gtacgtcagc acgtttaaag
     3361 tgagttctta acctggtttg tagagttcga ttattggggt actcatttat gaagtcagaa
     3421 aagactacag tttcagagcg cccaagttgc caagcttctt gtacttgtct atgtttgtac
     3481 tgcttcagca tactaacagt cgcttgatct atatcgatat cacgatagct agattttgat
     3541 ttaggactat tgagttcttg attatagttt agtgtttttg tgatatgcac aatagcatta
     3601 tctaagtcaa tatcagacca tgataaggct aaagcttcat tgatacgaca accagtagca
     3661 agtagaaact tataaagtgt aatctcataa taatagcgat acctacttag atccagagta
     3721 tctaagtatt taagaaagct ttttaattcg tcattatcaa agtgctttac tttttctcgc
     3781 tttgcttttt gtgtgttgcg aggtaatatt acctcacgag cagaattaaa cggtatagct
     3841 tgcataacta caccatactg taaaatacgc ttatttaaag cgtgtaagct atcgtagtat
     3901 agaaaagcgc cttcttcccc tttattggtt ttgtcagcaa gtttattgac tatattttga
     3961 ataagtggag tagttagttt atccaactta taagagccaa ataaaggtaa gatatggtta
     4021 tctagcagtc ttctaacgtt taattgtgtg ttaggtttta ctgtatgctt gtaactttcc
     4081 caccataagg aagctaattc cttgtaagta gtaatatttg aagcctggaa tctagtagat
     4141 ccattttgta aaaaagcaat ttcagcttct tttgtctttt gcttaacttc tttttttgtc
     4201 cttcctgtta tgcttgtctt tacatctttt ccagtgactt tatcaacacc aagatagaca
     4261 ttagcacgat atactattga accgtctttt tttgtgattt gttttatttg catagtattc
     4321 ttttccatca gcaggcaagc aattagaaaa ggttttgagt ttataccatg ctaggagcta
     4381 cgagaacccc tctattttcg attttaagag aacgaacggt aaaatgtacc aggtaagaaa
     4441 atgaagcgat tatggaactt ataaagggta ttaattagat aatcttctca aataccattg
     4501 tggcttgaat gcggtcacca ccgcctaaac ctttgcttcc accattggcg gttgtgatgg
     4561 tatgcaggtg ataagttttc tatggatcca gataaaagac agaaaatctt ttctcagtgt
     4621 aaaaaagaag gtgatagctt agaacaacgg aaacaagaaa tactagagaa atatgctaac
     4681 aaacaagaca aaccaaaatc tagaaaaaat gattctaaag gctcggagag tcataaaaga
     4741 aaaactaaga gcaaagaatt ttagaaaaaa ttataaacaa aaatcagata ttaaaagatg
     4801 aaggagcaaa aaaatgacaa ctaacttagt taaacaaaaa gaaaatttag aagcttatat
     4861 ccgaagtaca ggttataaca ctagagggat gaatgtagaa aataatcatg tactcattga
     4921 aaaaccaatc cttgatagtt acgaagatga acatcaacgt aaagaactgg ttgatctagt
     4981 aaatgttatt gagactcgta cccgtggcgg gaagtatgag gtaactgact ttgaatctga
     5041 ttcattacaa gaaattagtg aaaattttgt tgagagaaca gaatcagata aaaagaaaac
     5101 tatcagcgtt gattacttag ttaaattatt cagtggaaaa cttgattttt cacaggaaca
     5161 attagatgat ggccaatata atttaacgga ttttcttggt aagaagatta ttaaattaaa
     5221 acgtagaaca cgaaatagag agattgggaa aattctccaa actgcgaaag tacagaccgc
     5281 tacaagtctg gacgacttga aatctattgt ttctttaatc aatccagagc gcaatgtatc
     5341 tatagttatt agtcaatcac tatttagtgt cttagaaaaa atgaaagaca cttcaggaaa
     5401 ttatcttctt aaagttgata aagagacagg aacgagtgaa acattctttg tagataactt
     5461 tttaattgta gatgatacga cattagggaa cgaaggcgac aaaaaaggat ttatcggaga
     5521 tctagaaaac tttgttactt tgtttgatcg aaagaaagat acacttagtt gggtgaatgc
     5581 gaatgactat tttagaaaac ggttgatttt acatacccga tttgatgtaa aaaaagttga
     5641 agaagattgt ggttacttta ttcaatggaa ctaggaggaa gaaatggata ttaatcaagt
     5701 atttgataca ctggatgatt tagataataa aaaaagtaag atttattcag cacgagaaca
     5761 gttaagcgaa aaaaggaaga gtcttttagg cattcaaaca gtttcatttg agaatataaa
     5821 ttcttttttg tcaaataact tagaatcttt agaaaagctg gaaaagatgg aaaaagctat
     5881 taattctctt caggaaaaat ataatagtga tttttcagaa gctaaagcag tcatctttga
     5941 atacattttt aaagaaacta agcaacggat ggaaactaag aagatctata aacaataccg
     6001 aaagaaactt agacgaattc tggacgcata tgatgaaatt caagaactaa agaaggatgt
     6061 agaagaaatt catacaggtg tagtcaggga aataagtcag aaacattctc tatcgctata
     6121 tcgaacggaa gtaagtccgc ttactgtcct accattctta aaccctgata ttagcgggtg
     6181 gatggatttt tctaaggaat atcgggacat taaagagtat ttagaaaaat agggaacaaa
     6241 ttaagtaagg ctagtgatat atggctgaaa cagaagagat atcgctagtc ctacttttat
     6301 gctttactaa gtttcacata acaaagtaag cataaactaa aatagagtat aggcttggaa
     6361 gtcatatata tcagtaagtt acagaatgga gtgagtttca cagaatgtaa gatatgagaa
     6421 acttagggga taaattaaag aaatttccct tgaacttgtc atattgaaga gttgtcaaac
     6481 ttaaaacaat gatacctggt aagtggagtg ttggaaggct tttagcgctt tttgtcagtt
     6541 tgacagaatt tacaatttga caaattgaaa gataaaaaaa tttttaaatt taagtggagg
     6601 tacttgccta tgtacgagtt gagtaacaga gacctggacg ggatagatat tgagttagga
     6661 cgatatagaa cgcttgctag taaaatttat ttaagaagac aggaactgat acataataag
     6721 aaacatagca ctgaagatta tactggtgga aaaggcaaga cagtatatag tcctaccgaa
     6781 gcaactatta ttagaattga agaagaccaa acactaagat atttagaagg tttcaaacta
     6841 attgtagata ccttgatgga aaatctgatt gatactgatc tagtcatctt taaaatgaga
     6901 tttttagaag ctggtgtgac ttgggaagat gtggcagaga aactaaataa aactactcgt
     6961 tatataaata gtcgaagaaa agtaatcgct aaaagattta tagaactgaa aggatattga
     7021 ctccccccac gttgaaaaaa attttttgaa tactttgaga accggtgaag ggaacttttt
     7081 ctaagtcgga gacctccaga caaaaagggg gtaaaaactt gttgatttat aaggtgaagg
     7141 ctagtttttt gaaattaaac atatgcattc aaaagtcatt gaaataaatg aggaggttaa
     7201 actgaagata atttttctag attaaagtga agctatgata tattgttaga aattggagat
     7261 gtgtttgcat agttaaaaga atgtactttt agtatgaatt gtattataat tagttaaagg
     7321 gaattgttgt ataaattgaa aaatatttaa tgatttttaa ctgttaagtt atgtaaaata
     7381 attggaggct caattttgac tgcagaaatt ggaatactaa ataagaatgg agttgtttta
     7441 gctgcagata gcgcggtgac tttatctgac gggattaact ccaaagtgtt taatagtgct
     7501 cggaaattat ttactttatc tagagtgcat tcggttggaa ttatgattta tggagatgcc
     7561 tcctttatgg gtgtaccgtg ggaagtaatc ataagtgagt ataaaaagtc aattggcaac
     7621 gaagtactag ctgacacagc aatgtacatt aataattttg ttgatttttt attgcaattt
     7681 atgctaatac aaagtaatga tgccttggtt aattatataa ttagacagac tagaagttat
     7741 ttaaaaataa tacacgagag cacccaagaa atagctgatc atagatcaga tcagggagat
     7801 gtaataactc tagaaatttt taaaaatatt ttatgggaag ttatagaaga atattcaaat
     7861 gatatctcca aatcaatatc tgaaactgaa tttgaatatt tagatggcga acttgattta
     7921 atacgggaac aactagatga gtactttaac aataatgaat actccgatga gcaactaaac
     7981 tttttatcta aaacaatata caaagcaatg ttagttggtt ttgatagaaa ttctgtaaca
     8041 gggttggtaa ttgctgggta tggtgttgaa gaaatttttc catcccttag acaaatagag
     8101 ttaagtggtg tatttgctaa acgccttgtc tggcgtgtaa ttaccgagaa agaaattagc
     8161 caaaatgttg cttgtcatat tattcccttt gctcaatccg aaatggtaga tactataatg
     8221 aatggcatag atccaatgtt aaacgcattt ataggacaac aaattaatga aattttggaa
     8281 agtaataata tatcggatgc acaggaagag ttgtttgaaa ctatcgctag agtccaacaa
     8341 caatattata taaatccaat ttttgagttg attgggatgc aacctattga tgagatggct
     8401 tctactgcaa aaacattcat tgagttgact tcttttaaga gaaagattgt gaatacactt
     8461 gaaacagttg gaggaccagt ggatgtttta gctatttcta aaggggaagg tcctatctgg
     8521 attgaaagaa aacactactt taatattgaa aataatattg attataaaat tagaaagggt
     8581 gatatataat gtatgcagca aatttttcaa aagaaaaata tggatttcta gataaaaaaa
     8641 tatatcagaa tctttcacaa agtaatgttg ggaaaaattt tttagaagta tataaagaga
     8701 tagacactaa accaaaaaat caaatcagta aaactcttgt tgacaagtct atc
//
LOCUS       DAVKAU010000065         8668 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVKAU010000065 DAVKAU010000000
VERSION     DAVKAU010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8668
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.065"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..330
                     /locus_tag="VWX48_001853"
     CDS             <1..330
                     /locus_tag="VWX48_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU9172424.1"
                     /translation="AFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNS
                     QDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKLKGLSPVQ
                     YRTKSFG"
     gene            complement(457..660)
                     /locus_tag="VWX48_001854"
     CDS             complement(457..660)
                     /locus_tag="VWX48_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9172425.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(653..1735)
                     /locus_tag="VWX48_001855"
     CDS             complement(653..1735)
                     /locus_tag="VWX48_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9172426.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1861..2643)
                     /locus_tag="VWX48_001856"
     CDS             complement(1861..2643)
                     /locus_tag="VWX48_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU9172427.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGTHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2643..3986)
                     /locus_tag="VWX48_001857"
     CDS             complement(2643..3986)
                     /locus_tag="VWX48_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU9172428.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4085..5401)
                     /locus_tag="VWX48_001858"
     CDS             complement(4085..5401)
                     /locus_tag="VWX48_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU9172429.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5595..6821
                     /locus_tag="VWX48_001859"
     CDS             5595..6821
                     /locus_tag="VWX48_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU9172430.1"
                     /translation="MKSNRYIIAFTGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7020..8594
                     /locus_tag="VWX48_001860"
     CDS             7020..8594
                     /locus_tag="VWX48_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9172431.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVSPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2493 a         1678 c         1925 g         2572 t
ORIGIN      
        1 gcattcacag agaagcacta tgagaatacg attctccata gtgaccaagg ctggcaatat
       61 caacacgatt cttatcatcg gttcctagag agtaagggaa ttcaagcatc catgtcacgt
      121 aagggtaaca gccaagataa cggtatgatg gaatctttct ttgggattct gaaatcggaa
      181 atgttttacg gttatgagaa gtcgtttcag tcgcttaagc aattggaaca agctattgta
      241 gactatattg attactacaa caataaacga attaaggtaa aactaaaagg acttagccct
      301 gtgcaataca gaactaaatc cttcggataa attaattgtc taactttttg gggtcagtac
      361 agaaaaactt tgatactatg cgttttattg tgggaagatt ttcctcattt tctagtgaaa
      421 ttgaactttt tctaacatct tttgatagat gacttcttaa tcaattatca tttccattgt
      481 tgtttcttgg ggtttcatcc cttgtctttg ataaaagcgg agagcaccct cgttatcatt
      541 ccagacactt agggttagat tattgcagcc aatttcttta gcataatagc agaaaaatga
      601 caataaaata gcccctagat attttgaaag gaaagcatag gggctatata gtttaatcaa
      661 aataaagcaa atctttgctg gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac
      721 cgcagtcttc aatacgaaca ccgactttac cagggatata gatacctggt tcaacagaga
      781 agcacatgcc ttcttcgatg accatgtcgt ttccttccat gatagatggg aattcatgga
      841 catccatacc gataccatgc ccgagacggt ggttgaagta ctcaccataa ccagcttttt
      901 cgatgacctc acgggcagcg cggtccactt catgagcagt cacacctggc ttgataaagt
      961 caagagcagc ttgttgggct tcaagagtca agttgtaaat atctttcttg aattggtctg
     1021 gtttgccgac agcgactgta cgagtcatat ctgacgcata gccattgacc agaacaccca
     1081 ggtcaaagag gagaagagca tcattttcaa ccttattagc tgctggaatg ccgtgtggat
     1141 tcgcagcatt atcaccagtc aagaccatgg tatcaaagct catttcgtaa ccttcacgtt
     1201 tcatggcaaa gtcaatttgt gcgatgatat ctgtctcagt cttatcaaga gaaatattgt
     1261 caaaaccaac atgaacagcc ttgtcagcat aaagacctgc aaccatcatt ttttgtactt
     1321 catcagctga tttgatgagg cgcatgcgtt ggatacgagg agtgaggttt tcaaactcag
     1381 cagtttcaaa aactgttttc aaaccatggt atttggtcaa gatgagattg tcaaactcaa
     1441 cagcgacacg tttgaagtca agttgtggaa gagcatgttt gattttttgc catggatttt
     1501 cagaatcgac atagcccact actgggaagg aaacggtgct acttgcacgt tctacttcaa
     1561 gagctgggac aaagaggaga ggttcctgat ccgctaggac aaagaggaac atttggcgtt
     1621 catggggatc actgtaaaaa ccagtgaggt aattgattgt gacggggtca gatacgacag
     1681 cgacgtctag tttttctgat tcaagatatg ttaggatttg ttgtaattta gacatatgct
     1741 accttctttc tacccctcta ttttggcaaa aaatgagaga aaatgcaagg gagaagggta
     1801 aaagaaaaga caaaaaactc cgacaagata acggagttct ttgatatcat tttcctttgt
     1861 ttaagaaaag tcagccttgc ttttgacgtc actgtactct tcagcgattt cttggctgag
     1921 aatgtcctca taggcaggga gttggatgtc ctgaccatat ttcttcttga gggcagtagt
     1981 aactaggcga taagccagat tggcattacg agagaggata ggcccgtgga agtaggaacc
     2041 aaagacattc ttataatgaa ccccttcacc gaccttttct tcgttgtttc catttccata
     2101 gacaacctgt cccagcggtt tttggtcatc agagaggaag gtacgacctt ggtgattttc
     2161 aaatccatag taggtttcat cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg
     2221 gttattggtc tggttgagcg tgtagtgtcc catgacccct agcccttcga tacgttttcc
     2281 tgaagcttca acataatatt gacccaatag ttggaaacca ccgcagatag ccagaactac
     2341 accgtcgttt tggatgtagt tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat
     2401 gatactttgt tcaaagtctt gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc
     2461 aaagtcatca tggagagaaa cgatgtcaac ggtcacatgg gttcccagtt tttcagccac
     2521 atacttgagc atgaggatgt ttccattgtc cccgtaggta ttcatgagat ttccgtagag
     2581 gtgggcaatg ttgagctgat aggggtaatt gccatctttt gaggaaagtg aagtataaac
     2641 cattagttca tctcctttct aacaatctga cgactagcca gcagttcacg aaattccagc
     2701 atggcagtat aagttgccag aatataggca tgcttgcagt cttgattctc aatggtcttg
     2761 agaacttgct ccagattact cgtttcagtg attttctcag ctggatagcc agtcactcgg
     2821 aggcgacgag cgatttcaga atgacgaaca ccgccagcgt tgatttcagg aatgtccatg
     2881 tcagtgattt gctcaaagtc tgcatcccag atccagctag tgtcaattcc atctgcatag
     2941 ttggcattaa ggaggacaga taggctaaat ggataaggtg ctagtttgat catttcgata
     3001 gcttgggttg caccgactgg atttttaatc aagacaaggg tacattcctt gtcaccgata
     3061 tgaaaggttt cttggcgtcc aaagacagca cggctcttgt caaatccctg tttgatgagt
     3121 tgcgaatcgg cacctaggaa acgggcgatg gccacagcag ctagggcgtt atagatatta
     3181 tagagcccgc cgatttggat accgtattct tggccgtcta tgacaaagcg agagcgattg
     3241 ttggtcaact caaccagttt tgtcaaacga tagtcgagat caggacgttt acatccacaa
     3301 ccctcacaga tataggcacc caagtttgca taggtattat gctcatattt gaggatgcct
     3361 tggcagtcag gacagagaat cccttcggta ttgtagtgag ccagttgggc tggtcctttt
     3421 tccaagtcaa aaccaaaata ctctataggg tttggaatag ttggcttgta gaaaagtgga
     3481 ctgtctccgt taaggagaac agtagcagtt ggaactttcc gaatggcatc caatatcatg
     3541 ttataggtag tatagatttc accgaaacgg tccatctggt cacggaagat attagtaatg
     3601 acaaaaagac taggctggat atagtcacag atacgagata gactggcttc gtcaatttcg
     3661 aggacggcaa tatttttccc agttttagaa gatttggctg ttaggaaggt tgttgcaatc
     3721 cctgtaatca tgttggcacc gcttgggttg gttagaactt gaccataaac ctcttttaaa
     3781 atgccgacag tgagggcagt tgtcagggtt tttccatttg ttccagtgac aacgacaatc
     3841 tcgtagttct tagctaggtt ttgtaaaata tctttatcaa attgaagggc gactttccct
     3901 gggagcgtac ttccacgtcc aagacggctt aaaacgaagt gggaagaacg cccagcaaga
     3961 aggcccaaag tagtttttaa gttcatgttt ctattatatc acaaaagagg gaaaagacag
     4021 atttggtgtt tcgtagaagt aaaaacagcc caaagagggc tgtcagttaa gatgagattt
     4081 caacttaaat cgcaaacaag tcattcaagt tctcagccaa ggttgggtga gtgaagattt
     4141 gttttgtgaa gtaagtgtaa ggaatcttgt tgtccatagc aacagtaatg atgttgatga
     4201 tttcttgaga accttctgag aagatgcttg caccaagaat ttcttttgtt tcagtattaa
     4261 caacagcttt gaaagctccg cgaaggtctc catttacgtg accacgaggc atggctgcaa
     4321 cagggatttc tttcactgcg tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac
     4381 caacttgtga aagtgcaggt gtgatgaaca tagtatttgg tacattgaga cggtcctcaa
     4441 gtgtgtagct gccatctcca gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa
     4501 tgtaagtaaa ttgaagacca ccgttgacat ctccaactgc aaagacacca ggaacgtttg
     4561 tttgacagtg tttatctact ttaatagcgc cacgttcagt tagttcaata tctgtatttt
     4621 caagttgaag tggttctaca tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac
     4681 ggtaagtttc gtcttcagtt acgacaagca cttggtcacc gtcgttttta atttcagtag
     4741 tatggatatt ttgaagcaat tcaataccgt cttcttccag gtattgttta gcaagagctg
     4801 cgatggaagg ttctgcacga ggtaggaatg tatccaaggc atctaggact gtaaccttgc
     4861 ttcctagttt attgtaaagg ccagcaaatt caagaccgat atttccgcca ccaaggactc
     4921 caagtttttc aggcaattta tccaagcttt ggatacctgt tgagtcaaag acgtttttgc
     4981 ttgtagcaag tccagggatt ggcaagacgt ttgaaacagc accagtgttg atgacgatag
     5041 tttcagcagt caattcttgt ttttcatcac cagcttggat ttcgatgact ttatttgaaa
     5101 ggaagtgagc ttcagcatca aagatatcga cgccagtacc agcaacagtc gtatagtttt
     5161 taccgttgag gcgaccagtg atcgtgtttt tggtagcaat gacttcttca aaagacaagt
     5221 ctttctcagc agcaaccagc aaagttttag ttgggataca accgatgttg atacaagttc
     5281 caccgtacat agctttgcta cgttcaacga gggcaacttt tttgccagct gaagccaatt
     5341 tacctgctag tgttttacca gctttaccaa atccgataac gattaaatca taagttaaca
     5401 tttagagttc ctcctattcg catttcattc tagcacaaga aaaaaacttt tgcacaattc
     5461 tgctacggaa aagacagaaa aagataaaaa cgctttccag acaaaaaact agtaattttt
     5521 tgacaagctt gataaactaa aatcctatct atttttatat aagatagaat aaatgttcga
     5581 aaataggagg ttttatgaaa tctaatcgtt atattattgc ctttactggg gtcattttac
     5641 acttaatgct gggttcgact tatgcttgga gtgtttatcg taaccctatt attgaaaaaa
     5701 cgggatggga tcaggcttct gttgcctttg cctttagtct agcaatcttt tgtttgggct
     5761 tatcggctgc atttatgggg cgtttggtag aaaaatttgg tccgagagtc atggggagtc
     5821 tatctgcttt tctatacgca ggtggaaata tcttaacagg atttgcaata gaccgtcagg
     5881 aactgtggtt gttgtatctc gcttatggca ttttaggtgg gcttggtttg ggagcaggct
     5941 atattacccc tgtgtcaacg attataaaat ggtttcctga taaacgtggt ctcgcaacag
     6001 gtttagcgat tatggggttt ggttttgctt ctttattgac tagtcccata gcgcaacatc
     6061 tcatcgcagg ggtagggctt gtagaaactt tttatatttt aggtgcaagt tactttatta
     6121 tcatgctcct agcttcacaa ttcattaagc gtccaaatga gcaagagctt gcaattttat
     6181 ctgcttcagg gaaagaaaaa acagactctc tgacgcaagg gatgactgca aatcaggctc
     6241 taaaaagcaa tcggttttat atactttgga ttattttctt tatcaacata gcttgtggtt
     6301 taggcttaat ttcagcggca tcgccaatgg cacaggagat ggctggcttg tctacaagtc
     6361 atgcagcagt aatggtgggc gttttaggga ttttcaatgg atttggtcgc ttgctctggg
     6421 cgagcttatc tgactatatc ggtcgccctc taacctttag tatattactg cttgttaatc
     6481 ttttcttttc tctctcactt tggctcttta cagattccgt tttatttgta gtcgctatgt
     6541 ctattttgat gacttgctat ggagctggtt tttcattgat cccagcttat ctcagtgata
     6601 tttttggaac caaggaattg gccgctctgc atggatatat tttaacagct tgggcaatgg
     6661 ctggtttagc gggacctatt ttattagcag agacttataa aatggctcat tcgtacacac
     6721 aaaccttgtt cgtttttctc attttataca gtatcgcctt ggctttgtct tattatctag
     6781 gtcgttcaat caaaaaagaa agtcaaaaac cgcttacatg attttctgta gaaatggggc
     6841 tatcttttgc tctggtcttg tgttatacta gataggttgc aaagaaaaca gtacttttct
     6901 tttgtggaaa agaagcaaca cgattttata tctagttata tgaaaatacg tcataaaaag
     6961 aaaagtataa actaagccct atagggtggc ttcgcaccac ctttagaaag aagaataacg
     7021 tgaaatttaa tgaattaaac ttgtctgctg atttgctagc agaaattgaa aaagctggtt
     7081 ttgtagaagc tagtcctatc caagaacaaa ctattccttt ggcccttgaa ggcaaggatg
     7141 ttatcggtca agctcagact ggtacaggaa aaactgcagc ctttggcttg cctacccttg
     7201 aaaaaatccg tacagaagaa gcgactatcc aagctttggt catcgctcca actcgtgaac
     7261 tagctgttca aagtcaagaa gaactcttcc gctttggtcg tagtaaggga gtcaaagtcc
     7321 gttcagtata tggcggatca agcattgaaa aacaaattaa ggctcttaaa tctggtgccc
     7381 atatcgtggt gggaactcca ggtcgcctct tggacttgat taaacgcaag gccttgaaat
     7441 tacaagacat tgaaaccctt atccttgacg aagcggatga aatgcttaac atgggcttcc
     7501 ttgaagacat cgaagccatt atttcccgtg tacctgagaa ccgtcaaact ttgcttttct
     7561 cagcaactat gccagatgcc atcaaacgta tcggtgttca gtttatgaaa gcccctgaac
     7621 atgtcaagat tgcggctaag gaattgacaa cagaattggt tgaccagtac tatatccgtg
     7681 ttaaggaaca agaaaaattt gacaccatga ctcgtctcat ggatgtggca caaccagaac
     7741 tcgctattgt atttggtcgt accaaacgcc gtgtggatga attgactcgt ggtttgaaaa
     7801 ttcgtggctt ccgtgcagaa ggaattcatg gcgacctaga ccaaaacaaa cgtcttcgtg
     7861 tccttcgtga ctttaaaaat ggcaatcttg atgttttggt tgcgacagac gttgcagcgc
     7921 gtggtttgga tatttcaggt gtgacccatg tctacaacta cgatattcca caagatcctg
     7981 agagttatgt tcaccgtatc ggtcgtacag gtcgtgctgg taagtcaggt caatctatta
     8041 cttttgtttc tccaaacgaa atgggttacc ttcaaatcat tgaaaacttg actaagaaac
     8101 gcatgaaagg tctcaaacct gcaagtgtag aagaatcctt ccaatcaaaa aaacaggtag
     8161 ctctcaagaa aatcgaacgt gattttgcag atgaaaccat tcgtgccaac tttgagaaat
     8221 ttggtaagga tgctcgcaaa ttggctgctg agtttactcc agaagaattg gcaatgtata
     8281 tcttgagtct gacagtccaa gatccagata gccttccaga agtggagatt gcacgtgaaa
     8341 aaccactacc gtttaaacca tcaggtaatg gtttcggtgg taaagctaag ggaggtcgtg
     8401 gaggccgtcg tggggacgac cgtcgagagc gtgatcgccg tggcaatggt cgccgtgatg
     8461 agttcaaaaa aggaagtcgt ggcaacgatc gttttgataa ggaaaaacgt taccgtaagg
     8521 ataataaaaa accacgcaat actttaagcg aaaagcaaac aggctttgtt attcgtaaca
     8581 agggcgataa ataagaaaaa gcggttcaaa atgaatcgct tttttatata aggagaccga
     8641 atgtgaaaag acaaataaaa ttatcata
//
LOCUS       DAVKAU010000066         8208 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVKAU010000066 DAVKAU010000000
VERSION     DAVKAU010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.066"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..612
                     /locus_tag="VWX48_001861"
                     /pseudo
     CDS             1..612
                     /locus_tag="VWX48_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1350..1610)
                     /locus_tag="VWX48_001862"
     CDS             complement(1350..1610)
                     /locus_tag="VWX48_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172432.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1669..2220)
                     /locus_tag="VWX48_001863"
     CDS             complement(1669..2220)
                     /locus_tag="VWX48_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172433.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYTLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(2210..3205)
                     /locus_tag="VWX48_001864"
     CDS             complement(2210..3205)
                     /locus_tag="VWX48_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172434.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLSISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            complement(3613..4038)
                     /locus_tag="VWX48_001865"
     CDS             complement(3613..4038)
                     /locus_tag="VWX48_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172435.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(4167..4525)
                     /locus_tag="VWX48_001866"
                     /pseudo
     CDS             complement(4167..4525)
                     /locus_tag="VWX48_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835110.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4571..4777)
                     /locus_tag="VWX48_001867"
     CDS             complement(4571..4777)
                     /locus_tag="VWX48_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172436.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTHFSLIAVNSDMPLGR"
     gene            complement(4764..4925)
                     /locus_tag="VWX48_001868"
     CDS             complement(4764..4925)
                     /locus_tag="VWX48_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9172437.1"
                     /translation="MYMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(5316..6272)
                     /gene="lytA"
                     /locus_tag="VWX48_001869"
     CDS             complement(5316..6272)
                     /gene="lytA"
                     /locus_tag="VWX48_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU9172438.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(6648..8018)
                     /locus_tag="VWX48_001870"
     CDS             complement(6648..8018)
                     /locus_tag="VWX48_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9172439.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLDQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILLQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIAQGLRIGSRLSISWAVFVCIF
                     LFFASPALISFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
BASE COUNT         2653 a         1663 c         1324 g         2568 t
ORIGIN      
        1 atcgaactta tgaagaaatt gcggctgatt ttggtatcca cgaaagcaac ttactccgtc
       61 ggagccaatg ggttgaagta actcttgttc aaagtggttt tacgatttca agaactcctc
      121 tcagttctga ggacacggta atgattgatg cgacggaagt aaaaatcaat cgccctaaaa
      181 aaagaattag cgaatgattc tggtaaaaag aaatgccacg ctatgaaggc tcaagcgatt
      241 gtcacaagtc aagggagaat tgtttctttg gatatcactg tgaactattg tcatgatatg
      301 aagttgttca aaatgagtcg cagaaatatc ggacaagctg gtaaaatctt ggctgacagt
      361 gattatcaag ggcccatgaa gatatatcct caagcacaaa ctccacgtaa atccagcaaa
      421 ctcaagccgc taacagctga agataaagcc tgtaaccatg cgctatccaa ggaaagaagc
      481 aaggttgaga acatctttgc caaagtaaaa acgtttaaaa tgttttcaac aacctatcga
      541 aatcatcgta aacgctttgg attacgaatg aatttgattg ctggtattat caatcatgaa
      601 ctaggattct agttttgcag gaagtctatt atatatgcac agacatatga aatctttttg
      661 agacagcagt tatgatatat ttatccattc acaacatctt ctgtactaat actacaatat
      721 tggtacattt tgattacaca atcgtttcaa aaaatatgat ggaagcctga gtattttata
      781 gtaattccct tcctatcaac tagatcaacc agttgagtgt tgaatgttga aacaccctag
      841 cctcagcaaa ggactatgat cagcatttcc tagccaatag gacgctccaa atcacctatt
      901 ctaagtccat cactagcttg gtcagtaaga tacagactgc aaggcgagac tgatgtggtt
      961 gatgagattt tggaagagta ttacaatcat agattcacca gtagacttga ccgcagattt
     1021 aactatagta gattgaaact agaatagtac acctctactt ctaaaacatt gttagaaatc
     1081 gatttgactg tcctgatcaa tttgtcctgt tctcgtttca ttttactata ctaaaaaacc
     1141 acctgaaaca aatcaagtga ctagaggata aaaacaaaaa ctgggcaaaa agttttgaaa
     1201 agcaaaaaac gcataatatc aggtcttgaa aaaccttgat actatacgtt tgattgtggg
     1261 aagattgact tcattttctc ctgaaattga agttttttct agtttccaga tataaacgaa
     1321 ttcaatatag ccatctcgct acaattattt taaccatcga gaaaattttt cagaatttca
     1381 aaaatttcat tttgatccaa tgaaatgtca tcattttgaa gaatagttga cttcacaggc
     1441 tctaattcta tcacaaagcg gtgcatgtct gcttttaccg cactacttga tgttatagcc
     1501 gataactttt catctcctag caaggaagct gtcaaacggg taatgtcatt caaatgcttt
     1561 ttaatggact tacttaaatc ttgagcacct gtagcagagc gctctctcat atccagccaa
     1621 gctttagcct taaaaataat taatactcaa tgaaaatcaa agagcaaact aggaagctag
     1681 ctgcaggctg ctcaaaacac tgttttgagg ctgtagatgg aagctgacgt ggtttgaaga
     1741 gattttcgaa gagtatagac cacaattact caataccgaa tacccctgaa tggtttcttt
     1801 ttcatgcacc aatatattat aataatcttc atccaataat aaggctgata aactagcatc
     1861 ttggtcaaaa tgtaagggaa tttctcggcc gtccttcttt aatgtatatt ctggtaagat
     1921 actaaatagt tcaatcatag aaggaaactc aggattagtt gttgtaaatc gaaaaagctg
     1981 cgctttctca tctttctgac ttccttgata ctctcccaat tctaaaaaat gattcaaggt
     2041 agtataaaat tccttatttt ttacttcatc aatgatgacc atatcataat cttttgttgt
     2101 gcgactttta aatccttgcg aatccaatac gatagaggta gcagttcccc caatcagaac
     2161 ataatagttc tgaaaatccg caaacgtttc ttgaaaaata actttcgtat tagctggcat
     2221 catcttctcc cagatactgt aatatcatat tttctagtgc ttcactctct tcctctatac
     2281 gtgggtcatc atcatctttt aaggtcaaat aaagagaaat cggatctaca aattgtttat
     2341 catgattatt tttaaaatca ttccaaaact cagatacaaa aggacgatat ttccatatct
     2401 ctagcatctt tccttttaaa atatgctgag aaagtggcaa ggataactga ttgaattttc
     2461 tctgccatat gacatagcta gtattttcat ccgtttcagc taaaaaagtt gaatgcgaca
     2521 aagcataagc accaccatat agaaggttag aaacagattt tatctgcttt atatcgccat
     2581 ctggcaataa aatccgtttt ttgatgggat taaataaaca tgacacggat tttaagaata
     2641 attctttctt tgacaccgta tatgtgtaaa gcttattttg cttgtttaac caatataaag
     2701 ctttaaaagt cctcaaacac ctataaattg ttgagtttgg aagtccagtg acttgtgaaa
     2761 gcaaatcaac atctactact ttttgacctt ttgtcaataa aaaggcaatc cacgttaatt
     2821 gttcgctagg tgttaattcc ttagggactt cagtatcatt cgcattgagt actagtccca
     2881 atggagggaa gaagaggttt cccttaaagt ctacaaacgg aactctagct tgaagtaatt
     2941 gctttttttc actgtctgat aacttcgaaa acaccaaaac aacatccata ttggcttttt
     3001 cacccatagt gcgagcctga gtaacaaatg aactcaaact cccccttctc ttttctttaa
     3061 tcaataaaaa tgattcctta tgaaaagtca tttgagtata ctcaaacctt tttacaaaac
     3121 tgattgataa agtcaaagtc agttcctcaa tactgacatc aacataaaag gattgaaaaa
     3181 ttgacattat ctttttgaca ttcatgtttt ttccttattc tatcattttt attatatttt
     3241 atcattcggt ataataaaat ataagttttt tgataaaata accaaaaact actccctatc
     3301 ccctctcaca ctaccctaca tatcgtttga catgcgactg atagttcagg aaaacttcaa
     3361 ggagaacttt tctctcatcc actatgcagg acttactatt tcacttctac tcctataggc
     3421 tcaatttgac acttttcttt ttcgaattgc tcatatgcct cctgaatagt gagttcgatt
     3481 tatccaaatt tatttttgtc tattttgatg aatacttcca cgaagatagt ctgaaaatga
     3541 atttgcacca attttccttc tctttttaag catattattc cagatatgat tgccctcttg
     3601 ttcagtaata aattacgctt taaacgcttc aatcagtata tctcctgttg tcatatgttc
     3661 taaagaaaat tcttctacat atgatttaac atctcttagg ttattacttc ctaatatccc
     3721 attatgcttt ttcgctaagg aaatagaagc cgcttctccc ttaccaataa tcttgttact
     3781 atcatgattt cttgttaaat ctctatataa tgcgtattct tcagttccaa tgtctatgct
     3841 cacaatctca gctgaaccct tagctaccaa ctgatctatc ctagatttta aatggggaat
     3901 tgtaggtata ttgatttcat catacacctc ttgtggaata acaattttac ccgaatagag
     3961 cttttctaaa agatgttcag taccaaccca taaaaatact gaaatacaat ctgcatcaat
     4021 aaatacacga ctagtcaaac gacaactccc ccctcttcat ctagcccata tacaatatca
     4081 tatctgaaag catctagtaa cagttcctca tacttccctt gcgaaattct gctattttct
     4141 aaaagttgtt cagtcaaatt aatatattat actaatacca tttccttttt actttctgac
     4201 aaaggacgat ataaacttgt atcatagcct aatcttgaag ctgtctctat aacactaata
     4261 tccatatttt taatttcttc tgcatcaagg tatccatcat tcctcaatct atataacata
     4321 gctttatgac tgataccata aaactgaccc aattttataa tatcttctac ttcaagatga
     4381 gttctattgg cattttctct gatttcctca accatcctat acagtgaaat gggaaaatta
     4441 aaaaataaga agcaaactga tccgcttttc tttcagtttc atctccttca ccaatcaaga
     4501 taagactgac tgaactcttc ttcacctcat cataataaag atgatacagt tcatgtgcta
     4561 aagaaaatct ttaccttcct aatggcatgt ctgaattgac tgcaatgaga ctgaaatgag
     4621 ttcctttata acagactccg ctaatattct ttccgagtcc ataaaatacc agcgtcaaat
     4681 tttctatctt ttgtaccaat ttaaaaatat ctatcggcga ttcaccatca gctcccaact
     4741 tttttctaag atttggagct ttattactta aatccattcg tgatattcct ttcacctttt
     4801 tccattttgg caatcatgct ttgattcaaa gacaaatact cagcaatctt atcttgagta
     4861 agatttgaag atattctaag ttcttttatt ctttttccaa catcacatac atttatcata
     4921 tacatttatc atattcattt atcatattca tacacctctc ataaaaagaa tagcacactc
     4981 ttgtcataat tttttaaata aaaaaattat gacaaaacaa ggaagcaatt tattgatgct
     5041 gcttaaaaat ctaaaattga tgatattaaa cctatttgat gaattcctat caaaaatcgt
     5101 atcttcaacc tcaaaacagt acttaaagct atccgactcg gtttacattg tcaaatttag
     5161 attttatttg agcataactt tctagtttgc tttttgattt ttgtttaata tagtagcaaa
     5221 aattgaagga aatatctcca caagaaaacg catactatta agctttttca agacctaata
     5281 atatgcgctg ttctgatttg aaagacattc cattattatt ttactgtaat caagccatct
     5341 ggctctactg tgaattctgg cttgtctgcc agtgttccgt ctggtttgag gtagtaccag
     5401 cctgttccgt ccgctgactg gataaaggca tttgatacca tggcgccttc tttagcgtct
     5461 aagtagtacc aagtgtcctt gtacttgacc cagcctgtct tcatggcacc ttcttcgttg
     5521 aaatagtacc acttatcagc gattttcttc cagcctgtag ccatttcgcc tgagttgtcg
     5581 aaccagtacc agttgccgtc tgtgtgcttc ctccagcggt ctgcaagcat atagcctgaa
     5641 ctgtcaaagt agtaccaagt gccattgatt ttctcaaact tgtcttttgg ataagagccg
     5701 tctgagtgta cgtaccagta gccagtgtca ttcttctgcc agcctgtttc aatcgtcaag
     5761 ccgttctcaa tatcatgctt aaactgctca cggctaatgc cccattttgc caagtaaggg
     5821 tatggatcca catggtctga gtggttgttt ggttggttat tcgtgcaata ctcgtgcgtt
     5881 ttaattccag ctaaactccc tgtatcaagc gttttcggca aacctgcttc atctgctaga
     5941 ttgcgtaaga gttcgatata aaggcggtag tccgtcatga actcttcttt agttgaatgg
     6001 ctttcaatca gttcaaccgc tgcataggtc tcagcattcc aaccgccccc aacgtcccag
     6061 gcaccattat caacaggtcc tacctgcatg atgcaaccgt tcccaacaat gtgcgagaaa
     6121 aaacctaatt ctgggtcttt ccgccagtga taatccgctt cattctgtac ggttgaatgc
     6181 ggattcccag ttgagtgtgc gtgtacttgc ctatatggtt gcacgccgac ttgaggcaaa
     6241 tctgttctta atttactcac attaatttcc atattctact ccttatcaat taaaacaact
     6301 cattttttac aatccaaaac cagaaactcc tttatttcta ccttacaaag aagacaatct
     6361 tagtcacgat taggcttgta gatagaacct caaaacgcac tattttgaca ctgtaaatag
     6421 gactgacaag gtctgcattc tatctacaat aacaccccag actaaaaagc ttttcaaaag
     6481 tatattttta cagtctctat atgtcctttt cataaatact atactttatt atatcatata
     6541 aaagaagtca aaagtctgtt aaactatttt caacaccaaa ctaaagaaga gaacacaagt
     6601 tttttcgatg ttcactagag gaaatggatt ttattcagta aatccaacta ggattgcact
     6661 ttggttgcca aaattgcctt tccttctttt atcaagggat gacggaatag tgagaagtac
     6721 agttgaactg tcatggcaac ccagataaga ggttcacaaa ggataacacc cttatatcct
     6781 gcccaaggaa taatcaaaac cacaaaaacg atttttccga ttagttcaat aaagctagaa
     6841 actagaggaa ggatcttctg ccccaagccc tgcaagcaat tgcgataaat caacaagagg
     6901 ctcaaaatgg gataaaaggc tgaactgatt tgcagataga gacttccatt ttctatcaag
     6961 taaccatctg tcgaactagc caagaaggaa atcaaggctg ggctggcaaa aaagaggaaa
     7021 atacaaacaa aaactgccca ggatatactt aaacgactgc cgattcgaag accttgagca
     7081 atgcggtcag gtcgcttagc tcctagattc tgagaagcaa aggtcgtcat tgatgcagaa
     7141 atagcggtca taggaagaag ggcaaaggtc ataatgcgtc gagctgccgt ctgggcacta
     7201 ataatcactg caccaaatgt attaacagaa gactgtaaaa tcacactgcc gatagataca
     7261 attgaactca tcaagcccat agccaaacct tgctccaaga gatccgcgta caagcttttg
     7321 tcccatttga aatgtttaaa ctgtggcaag agttctggca cacttttacg aatataataa
     7381 aagcagagaa ccgctgataa accttgtgaa ataatggtag caagtcctgc ggattgaact
     7441 cccagatgca attgcgtaat aaaatagaga tccagaacca cattaaccaa ggcagagaaa
     7501 atcagaaatc ccagggctgc tagactgtca ccaatagacc gcaacaagcc tgcaaaaaga
     7561 ttataagcaa agctgacacc tacacaggtc acaatcatag aaatatattg ataagattga
     7621 agaagaattt ctgcaggagt atctaagtat tgcaagagag gatacaagcc aagaaagccc
     7681 agtaacataa ctagaatgct caaaagagca cctaaaatcc aggtggctgc tactgcttcc
     7741 ttgattttag tgaaattccg agccccataa taacgagcaa tgacaatccc catgccattg
     7801 ccaacaccaa gtgtaaaacc tacaatcagg tcaaaaatcg ctgtcgtcgc tcctactgca
     7861 gccaaggatt cttgatcaag aaatcgtcca acaatcaaga catcagcagt gttatagagc
     7921 tgttgaaaaa tatttgatag caagattgga aaggtgaagc ttaagagcga gggaagaatc
     7981 ggaccatgta tcaggtccac tgttcgtttt ttattcataa agctattata tcagctttcc
     8041 agaggagcga caagaaacag caaacttata tatagcggaa tgaaataagg aaagtcaaat
     8101 cgatttttaa caatgtttta gaagtagatg tgtactattc tagtttcgat ctattatagt
     8161 tggttgagtt tggaatagta cgctgtagct gctaaaacat ttctagaa
//
LOCUS       DAVKAU010000067         7651 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVKAU010000067 DAVKAU010000000
VERSION     DAVKAU010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.067"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     misc_feature    77..212
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            251..751
                     /locus_tag="VWX48_001871"
     CDS             251..751
                     /locus_tag="VWX48_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU9172440.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            827..1195
                     /gene="rplL"
                     /locus_tag="VWX48_001872"
     CDS             827..1195
                     /gene="rplL"
                     /locus_tag="VWX48_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU9172441.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            1382..1552
                     /locus_tag="VWX48_001873"
     CDS             1382..1552
                     /locus_tag="VWX48_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172442.1"
                     /translation="MQKEGQSSRQFMKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            1552..1800
                     /locus_tag="VWX48_001874"
                     /pseudo
     CDS             1552..1800
                     /locus_tag="VWX48_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            1814..2137
                     /locus_tag="VWX48_001875"
     CDS             1814..2137
                     /locus_tag="VWX48_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172443.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     EVSYD"
     gene            2130..2510
                     /locus_tag="VWX48_001876"
     CDS             2130..2510
                     /locus_tag="VWX48_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172444.1"
                     /translation="MIDLYLSKNSRRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLKLTDFIEMILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            2523..2756
                     /locus_tag="VWX48_001877"
     CDS             2523..2756
                     /locus_tag="VWX48_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU9172445.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            2759..3346
                     /locus_tag="VWX48_001878"
     CDS             2759..3346
                     /locus_tag="VWX48_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9172446.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYCASLIS
                     FLWMYAQRKQAHKVNMKSRIKWIGIGLASLLIISLCFSLIHAQESTNQANLIGLQYQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            3548..3685
                     /locus_tag="VWX48_001879"
                     /pseudo
     CDS             3548..3685
                     /locus_tag="VWX48_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
     gene            3975..5378
                     /locus_tag="VWX48_001880"
     CDS             3975..5378
                     /locus_tag="VWX48_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEU9172447.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQKLESALKQYNGP
                     YILSDKRWDEVPIYLRYGVFRPSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYLYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAASGFRSWRETFPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            5562..6182
                     /locus_tag="VWX48_001881"
     CDS             5562..6182
                     /locus_tag="VWX48_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9172448.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYQCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            6197..6937
                     /locus_tag="VWX48_001882"
     CDS             6197..6937
                     /locus_tag="VWX48_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172449.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            6940..>7651
                     /locus_tag="VWX48_001883"
     CDS             6940..>7651
                     /locus_tag="VWX48_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9172450.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQMSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKVQIIFNIVILDIVII"
BASE COUNT         2584 a         1069 c         1527 g         2471 t
ORIGIN      
        1 aaagaaaaat cacgaaaaat tttaaaaaaa gtttgcaaaa atcttgcatt ctttttttga
       61 ctatgctata cttatatacg gtttaaaaaa actgcctaag acagtagggg agctcgactc
      121 ataaatatcc taccgaggac aaaacgtatc atgtaaaaag aagcgtattg tactttcgtg
      181 tctaggtttg ggcgcgtttt tctttttgaa aaattcccca agcaaaataa ttacggaggt
      241 gaacacacta atgagtgaag caattattgc taaaaaagcg gaactagttg acgtagtagc
      301 tgaaaaaatg aaagctgctg catctatcgt cgttgtagac gctcgtggtt tgacagttga
      361 gcaagataca gttcttcgtc gtgagcttcg tggaagcgaa gttgagtata aagttattaa
      421 aaactcaatc ttgcgtcgtg cagctgaaaa agctggtctt gaagatcttg catctgtatt
      481 tgttggacca tctgcagtag cattttctaa tgaagatgtt atcgcaccag cgaaaatctt
      541 gaacgacttt tctaaaaacg ctgaagcact tgaaattaaa ggtggtgcaa tcgaaggcgc
      601 tgtcgcatct aaagaagaga ttcttgcact tgcaactctt ccaaaccgcg aaggacttct
      661 ttctatgctc ctttctgtac ttcaagcgcc agtgcgcaac gttgctcttg cagtcaaagc
      721 ggttgcagaa agcaaagaag acgcggctta atcttaagct acacagcgta gcctagctac
      781 gaaaaaaact attataaaat ttaaaactta tttggaggaa ataacaatgg cattgaacat
      841 tgaaaacatt attgctgaaa ttaaagaagc ttcaatcctt gaattgaacg accttgtaaa
      901 agctatcgaa gaagaatttg gtgtaactgc agctgctcct gtagctgttg ctgcagctga
      961 tgcagctgat gctggtgctg ctaaagattc attcgacgtt gaattgacat ctgcaggcga
     1021 caaaaaagtt ggcgttatca aagttgtacg tgaaatcact ggtcttggtc ttaaagaagc
     1081 taaagaactt gttgacggtg caccagcact tgttaaagaa ggcgttgcaa ctgcagaagc
     1141 tgaagaaatc aaagctaaat tggaagaagc tggagcttca gttactctta aataatagag
     1201 tatcgcaatt tgattgcgga atccctattt accagtcttt gagagcgata agcgattgat
     1261 agaaactgat aaattgattt ggtttcctgc caaaaattct ttggcaggat ttttgtttta
     1321 ataaactttc gggggtagac actagattgt ctaccccttt ttttgtgttt cggaggtaat
     1381 tatgcaaaag gaaggacagt catcacgtca attcatgaag agtcatctca tgactatcat
     1441 gggagttgat attgtaaaag caactcagtt agttgatgaa atggaacaag taggtttaat
     1501 ccgatttgat gaatttggaa atgttggaat tttagtcttg gagggacaat aatgaagcgt
     1561 attaccgcta atcaatatca gacatcagag cgttattata agctccccaa acttttattt
     1621 gagagtgaac ggtataagaa tatgaaaccg gaggttaagg tggtttactc agttttaaaa
     1681 gatcggttgg agttgtcttt gagcaaaggt tggattgatg aggatgggac tatttatttg
     1741 atttattcca attcaaattt gatggcactt ttaggctgtt caaagtcaaa attactctcc
     1801 atgtgagttt gaagtgacat ttttagatga ttaccataaa aaacataact acccactatt
     1861 ttacgaatcc tatcttcaaa acgttatgga attccttgaa agtcaagaca taaagaatgg
     1921 ggttgatgcc tttgtagatg atcatcaaaa tctcgttttt gttttatatg gacaaggcta
     1981 tcgagccgag ggaaaagagg gaatacttac aacccaagta actgtaaaag cttatgatga
     2041 agacaagaaa ccgattaact tcgcaaattt attagattcc ttaatcgtgt cagaatatca
     2101 aatggaaccg aatctttggg aggtctccta tgattgatct ctatctaagt aaaaatagcc
     2161 gaagaaatca acttctttta gacttcttcc aaaactatgg catcgaggta tcttgtcatt
     2221 cagtttctga aatgacaaag gacaaattaa ttgagatgat gagctattct tcagattgtt
     2281 ttgagttttt atctccaaat ttattacgtt ttaagaatcg agataaccta aaattaacag
     2341 atttcatcga aatgatatta aaaaatcctg aactaaccat cagacttcct cttgcggttt
     2401 caaataagcg agtttatcca agtctgaatt tggaagaggc tagagctcta ttgccaagag
     2461 atacgaaaca attgatttac atggcgcaaa cacattattt atctaactaa aggagaagca
     2521 atatggctga acgattttgg gagaacttgt ccattatttt ggctgaaaga aatatcagct
     2581 ggattgagct aaccagaaaa atgtttgcgg gagagtttca ctatccaagt gaattgaatc
     2641 gtttgtatca aaagattcgt cactacaaga tggaacaacg aatgcctcaa agtccatggg
     2701 tagaaaggat tgtgcaggta ttagatttag attatgaaga tttatttcgg aggtaactat
     2761 gaaaagaata attccagttt atatattcca acaagtaaat gtcctattgg tatctctata
     2821 cttactgaaa tttctttgta tcggtgagtt aactatacta cagattctat attgtgcgtc
     2881 actcatttct tttttatgga tgtatgccca acgtaaacaa gcgcataagg tcaatatgaa
     2941 atcaaggata aaatggattg gtattggatt agccagtcta ctgattataa gtctatgttt
     3001 tagtctaatc catgcgcaag aaagcacgaa tcaagcaaac ttaattgggc ttcaatatca
     3061 agttccttgg ttttcatttt tattgttctt aatcaatgcg agtatggttg aagaatttct
     3121 gtatagagaa attttatgga acttggttag aaaattagat attcgagttg ctttgacaag
     3181 tgttttattt gccttagcac atcatccagg aaccattata gcttggtgtt tgtatgtatc
     3241 gctggggatg tttttagggc ttgtacgcta caaattggac ttatggggca gtatggggct
     3301 acatttggtg tggaacctac tagtttatag tttgctgctt ttttaaaata ggtaacctga
     3361 tttttaggta acttctaaaa ctaacttcca gttttgggag agagatggaa gttactttga
     3421 aaagttacgg aaacattatt ttctatgtga caacattgta tcattgcttg cattttactg
     3481 ctggagagag tataatgaat gtggataaag cacttaatcc caaaaattta aataggagga
     3541 gttagctatg gcagaagaag tattaaatct ttaattagta tctgttcaag ttgacgaaac
     3601 agatgaagtt gatggaatgc gatttagtac attcagtaca aaccgttgcg gtaactggag
     3661 tgcttttagt tgggaaaatt gttaattcat ttaaattgta aactttagag attctctgga
     3721 gttatggatg tcgttccaat atgtgcacgt tggaatgtta gtgcttatat ggggggaatc
     3781 caaaggattc tcccttttta ttttaataag tctgtctagc tatagatata ttaagtttga
     3841 tagaatttct tggagatttt gttatggatt ataatttcaa tttggagcat cctttctttt
     3901 tcactaataa tgattatagt acagatacta gcataaagta ctaagtaagt ctgcctttta
     3961 attggcacga agtaatgaat aatgatgagt gggtttatca ataccctatt ggaaaatttg
     4021 ttgaaagaca agggtggaaa atacacatta gttcagagta taatagttca cacgaattgt
     4081 tacaagatgt agcaaaaatt tgccatgaaa tgcgaattcc atttaaacat cttagtacag
     4141 aagacaaatt tatcatgcga aacgggaaat tggttagtcg aggattttct ggtaaattta
     4201 ttacatgtta tccaaatcaa aatgaattag agtcggtttt gcaaaagtta gaaagtgcct
     4261 taaagcaata taatgggcca tatattttaa gcgataaacg ttgggatgaa gtaccaatat
     4321 atctgaggta tggtgtgttt aggccgtcaa gggatgatga aaagaaggtt gctattgatg
     4381 aattaattgt tggcgatgaa gttgttaaag atgaacgttt accagtattt aaaattccaa
     4441 aaggtatagt gccccctgac tttttgaata aatggcttga caagaaagat aaaaaacagg
     4501 gagactttcc ctttattata gataatgcaa ttagattttc aaacagtggt gggatatata
     4561 atgctagact aaaagaagat gggaaaaaaa taattttaaa agaggctaga ccgtatacag
     4621 gtctaggatt tgatggtact tattcttcag agagattagc ttcggagtgc aaagcactaa
     4681 aaattctaaa tgaatggagc gagatgccta aaatatactt gtacggtaag atctgggagc
     4741 acaccttctt aggaattgaa catatgaagg gcgttccact aaatagatgg gttaccaata
     4801 attttccttt atatgaagtt gttgataaga ccaaagatta tctattgaga gtttcaaaga
     4861 tagtagaaaa actcatcgat ttaacgaata agtttcattc tgaaaatgta tatcatcaag
     4921 atttacattt aggaaatatc ttggttaagg atgaagatga gattagtata atagactggg
     4981 aacaggctgt cttttcgaat gatgaaaaag ttgtacataa agttgcagcc tctggtttta
     5041 gatcatggcg agaaacattt cccagtgaga tagattggta tggtattaga caaatagctc
     5101 attatttata catgccacta gtaactacat cagatttgac atacaactat gtaagtcaaa
     5161 ccaggataga aggaaaaaaa ctatttgagt ctttgggtta tacaagagaa catatagatt
     5221 atgtagaaag tttattgtca tatctagatt ctaaatgtcc acagattgag aatatttcca
     5281 ggaaaaaagt tttaaaaccc atgcatgaga ttagaactat cgagagtgag caagatatac
     5341 aagattttat tataaaagcc tttcttttag tgaactgata ggtattttct tagcaaacga
     5401 taaagtttta gggccgatac aatcaattgc ctattcatta aataagataa atacaaccat
     5461 taaggaaacc gtttttaaaa tacttaagtg gagagaagaa ttttatagac gctgaacatg
     5521 ataataacgg actgtatact tcatcaatag atgagataca catgaaagat gttgtatatt
     5581 ctattacacc agaaaataaa ttaagtattg acttctcatt taagtcacca tttagggtat
     5641 tattaacagg aacttctggt agtgggaaaa caacgatttt aaatttaatt aatggttctt
     5701 taaagccaca aaaaggttat gtaaatttgt tatcacatgg gaaaaagagt tcagattcaa
     5761 taccaacagt tgatcagaca ccatatattt ttgacactac tattcgtgag aacgtaactt
     5821 tatttcaaaa tgaatatttt tcagatgatc agataattga ggtgttaaaa aaggtaaatc
     5881 tatatgaaga attagaaaag atagatatac taaattatca atgtggtgaa aatggtagta
     5941 atttgtctgg aggtcaaaaa caaaaaatag ctttagctag agctctgatt agaaataata
     6001 aagtgtactt atttgacgaa atatcagcta atttagataa tgataattca aattccatac
     6061 atgatattct gttcaattta ggtatttcat ttattgaagt ttcacatcat tatgacttaa
     6121 atgacaagag atacactgat atatataaat tggaaaatgg aacacttttc aaaattaagt
     6181 gattggaggc aagaatatgg ataaagatta tatattaaaa gtgaaagggc tgtatcatca
     6241 atttttacta ggaaataata aaacgttgca agtgctgaaa aatgtttctc tttctgcttc
     6301 gagaggagaa tttataagta ttctaggaat tagtggttct ggaaagtcaa ctttattaaa
     6361 atgtatttct agtttgcttg aaccaacaag tggggaagta attttaaatg gaatcaaccc
     6421 ctataaaatc agaaatgcaa aattgtcaag tataagacgt aacgaagtat cttttatatt
     6481 tcaagcatac aatttaatac cttccctgcc ggtaatagaa aatatagcac ttcctttgcg
     6541 attatcacaa aaaaaattaa ctattaaaaa tgtagaaaac ttactcaaaa gaatgaagtt
     6601 taatgctggc ttaaacgatt ttgttggaac tctgtctggt ggagaacaac agaaggttgc
     6661 tatagctaga gcggttattg ctgatagtga tataatattt gctgatgagc caactggggc
     6721 tttagacagc gtttctcgtg aagtaatttt tgaattattg agagagttag taggggcggg
     6781 taagtgtgta attatggtaa cgcacgatat agaattggcc tcgaaaactg atcgtgcatt
     6841 aatattgaaa gatggaaaaa ttttcaaaga acttcataga cctagcgggg aagagttgta
     6901 taaaatctta gaggtacaat caactacgga ggaatagaga tgctcagatt agtttactat
     6961 caatttttac ataataagaa acaatggtta ggcgtttcac cagtaatttt tgtttcgagt
     7021 ttagttatgg gattggctgt taatggggta attaatgttg agaataattc gcaagtattt
     7081 gtcggacttc cagatcctaa accaattttt atgtttccga tagtattcgg aggagtaaca
     7141 ttattctttg tgctctctaa cataataaat atgttggttg aaatttttag agatgattac
     7201 gaacttctgg aggtgttggg agcaagtcgc cttcaactat catttcttgt ggggggacag
     7261 atttttatca tttcctcgat tattagtttt attgcatatc tatgctctat atttgttacg
     7321 tcaaattatt attatttttt acaatacttt ttcggggaaa atatattacc tgatatccaa
     7381 tttcaaatga gtgctgttgg atgtatcatt acagtagtgt tgatttcatt tttagccttt
     7441 ctaagtggtt gcttttatac gttcaagaag attagaaata ggaagagttc taaaataagg
     7501 catgttcttt caatagtaaa aagaatactg ctattggctg gttttagtgt tatctggttg
     7561 ctttctttgc aacaaatttt ccaagatagc acaattttag cgaaggtcca gataatattc
     7621 aatattgtaa tcttagatat tgtgattatt t
//
LOCUS       DAVKAU010000068         7600 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVKAU010000068 DAVKAU010000000
VERSION     DAVKAU010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.068"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(109..384)
                     /locus_tag="VWX48_001884"
     CDS             complement(109..384)
                     /locus_tag="VWX48_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU9172451.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(491..1330)
                     /locus_tag="VWX48_001885"
     CDS             complement(491..1330)
                     /locus_tag="VWX48_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9172452.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAVKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1472..2320
                     /locus_tag="VWX48_001886"
     CDS             1472..2320
                     /locus_tag="VWX48_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9172453.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILGWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2413..3330)
                     /locus_tag="VWX48_001887"
     CDS             complement(2413..3330)
                     /locus_tag="VWX48_001887"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU9172454.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3768..3973
                     /locus_tag="VWX48_001888"
                     /pseudo
     CDS             3768..3973
                     /locus_tag="VWX48_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4284..4577)
                     /gene="rpmA"
                     /locus_tag="VWX48_001889"
     CDS             complement(4284..4577)
                     /gene="rpmA"
                     /locus_tag="VWX48_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU9172455.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4594..4938)
                     /locus_tag="VWX48_001890"
     CDS             complement(4594..4938)
                     /locus_tag="VWX48_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU9172456.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4954..5268)
                     /gene="rplU"
                     /locus_tag="VWX48_001891"
     CDS             complement(4954..5268)
                     /gene="rplU"
                     /locus_tag="VWX48_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU9172457.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5305..5392)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5487..6086)
                     /locus_tag="VWX48_001892"
     CDS             complement(5487..6086)
                     /locus_tag="VWX48_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU9172458.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSVYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6557..6856
                     /locus_tag="VWX48_001893"
     CDS             6557..6856
                     /locus_tag="VWX48_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU9172459.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7076..7540
                     /locus_tag="VWX48_001894"
                     /pseudo
     CDS             7076..7540
                     /locus_tag="VWX48_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT         2417 a         1528 c         1264 g         2391 t
ORIGIN      
        1 attttcggaa cattcaactt tttaactcta tttattacta aatttcataa ttaaaaagcc
       61 tactgaccaa gctagaaagc ttgatacaat aggcttttta aagactgatt atttaacagc
      121 gtctttaaga gctttaccag ctttgaatgc tggtacttta gaagctgcaa ttgtcatttc
      181 tttaccagtt tgtgggttgc gacctttacg ttctgcgcgc tcacgaactt caaagttacc
      241 aaaaccgatc aactgaactt tttcaccagc tgcaagatag tcagctactg ctgcaaatac
      301 agcttcaact gctgctgctg agtctttctt agtcaattct gtagcttctg ctactttagc
      361 gatcaaatct tgtttgtttg ccatgttaat gattcctcca aataatttct aattaacaaa
      421 tataatcata tcctaaaatc ccttttaggt caagttaaaa acgctatttc ttcccatttt
      481 atttattttt ttaggagtgg taacgtatca aaatagccca agcgttctca cccgtgtgag
      541 tttgaataat ggaacccgtt tccaaaacag aaattggctt ttcaacataa gcttgtaagc
      601 tttctttcat ctcttttgcc caatcatcac taccagaata tgaaattcca atctctgcta
      661 cagcacgttc agaaagcgat gttatcaact catctaacca ttttttaaat gttttagttc
      721 cacgaccttt aaccattggc tgcaattcat ggtctttcat ttgcatgaca acacggatat
      781 tgagaaggga gctcaacaag ccagttacac ggccaattcg tccacctttg acaagatttt
      841 ccaaagttga aacaccaata taaagctctg tatggttttt aacctcttct acatgagata
      901 aaattgcctc catatcttta ccttcttgag ctaacttcac agcctcaaca acttggaatt
      961 tcagggcttg gtcagtgaag gaactatcaa caacagtcac atctgcagta gataggctag
     1021 caccttggcg tgctgcttct accgtacccg aaagagcatg ggacatatga atagcaagaa
     1081 tctggccacc atctttgcat aggtcttcaa aaatctcagc aaagacacct acaggtggct
     1141 gacttgtttt cggaagattc ttactttctt gcatcaactg aagaaattta ccttcttctt
     1201 tcaaatccgc atcagaataa acaacattat caatcattac agataatgga acaattgtaa
     1261 tatctaattg ctttactagt tcaggttcaa tagtaacaga tgaatcggtt acaatcttaa
     1321 tttttgtcat agtatcaatc tttctatttt aggattcaga ttggtttcct tacttctaat
     1381 tatatcaaaa aaaagattaa aaatcctaat ggagtcaatc aaattttccg taaaatttga
     1441 tataatcaac ttataagaaa agaggtgtcc tatgattaaa aaaatttacc ccatttttac
     1501 cattttacta ggtgctgcta tttatgcttt tggactgact tattttgtag ttccccatca
     1561 tctctttgaa ggaggggcga caggcattac cctcatcacc ttttatcttt ttaaaatccc
     1621 tgtttccctc atgaacctgc tgattaatat tccccttttc atcctaggtt ggaagatctt
     1681 tggagccaaa tccctctatt ctagtttact aggaacctta gctttgtccg gctggttagc
     1741 tttttttgag catattcccc ttcatattga tcttcaaggt gatttactaa tcacagccct
     1801 tatagcggga atcctattgg gaattggcct tggaattatt tttaatgctg gaggtacaac
     1861 tggcggaact gatattctag ctcgtattct caacaaatac actcatatat ccataggaaa
     1921 actgctcttt atcttagatt tttgtattct catgttgatt ctcctaatct tcaaggattt
     1981 gagattggtt tcctacacgc ttttgtttga ttttattgtt tctcgtgtta ttgatttgat
     2041 tggtgaagga ggatatgccg gcaaaggctt tatgattatc acaaaacgtc ctgaccaact
     2101 tgctaaggcg attaatgatg acctcggaag aggtgttact tttatttctg gtcaaggcta
     2161 ctatagtaaa gaaaatttga aaatcatcta ctgtattgtc ggaagaaatg aaattgtgaa
     2221 aacgaaggaa atgattcatc gaatcgatcc tcaagccttt ataactatta cagaagccca
     2281 tgaaatccta ggagaaggct tcacctttga aaaagaataa aaagaggtaa tgtcgtgacc
     2341 tcaaaagtta gactaaatca tctatctttt gggttacaga caacctcttt tttgttttat
     2401 ttactcaagc tcttaagacc aattccgagt tacttcttca tcagccttta actgatccac
     2461 taattggtca actgagtcaa atttggtcat atctcgaatg cgatcaagcc aataaaccat
     2521 gacggtttcc ccataaatat cttgattaaa atcaaaaata ttgacttcaa aacgtgcttc
     2581 ttctccatca aaggtcacat ttttcccgac actagccata gcacgatact tctgtctttg
     2641 aatctcaaca tcaacgacat aaacgccatc tgctggcata taagtacggt ctaaaagcac
     2701 taaattcgct gtcggataac caattgtacg accacgagca ttaccatgaa ctaccatacc
     2761 tcttgatgga agcggtgccc ccaaaagttt tcctgcttct ttcacatttc catctaaaat
     2821 agcttgacgg atacgagttg aactaatctt tcctttctca tcttctacag gtggaacaat
     2881 gataacttct ccatcaaagt aatcctttaa atcttctgct gtttttttgt cagaaccaaa
     2941 tgtataatca aaacctgcaa caataatttt ggcattcata gccttgatat aagttgcaaa
     3001 gaattcttgt gcagtgagac tagcgaattg actactaaaa tcaaggagat ataattcttc
     3061 tacaccttcg cgctttaatt ttctttcacg ttcagcaggg ttcaaaatat gcaaaaacaa
     3121 atctggatga taaggctcta aagcgatctt tggagattca ttaaaggtca taacgacgat
     3181 aggcaataaa tcctttctcg cagccttgtt ggcaacacga aataattctt gatgcccctt
     3241 atgtatgcca tcaaaatagc cgagaacaac gactgaatca gatggtgtgc caatatcttt
     3301 ttggtttttt ataggaatag taataatcat aaaataatta tatcatagcg atagctattt
     3361 ctggaacaga aaatctgaaa tgttgttttt ttcacatgaa gtgtacctgt tttcaaaagg
     3421 cactttattc tatcgttgct taactatgaa ctttgcaata ttcttctcaa aaacttgtag
     3481 gacatcttca aaattttgca aggagtgatt agacttgttc ggtaaccata aagtgtcata
     3541 ctatgcttat gtatgaaaaa gcaatgcaac taactcctga gaactttaaa ttactaattg
     3601 gtgccgaaaa ggtagaattt agaatcgagg tacacctatg gctgtaaaat ttacaaaatg
     3661 agacaacttg ggcaagatgt ttgaagaatt tcctaaactc cctgatttga agcaagtcac
     3721 tttccctgat gacaaagaaa aaagccaaag caataaagaa aaactagatg actgctttcc
     3781 aacaactccc atctagtgtg cttcagactg ggctattttt ctttccatct gttagcttgg
     3841 attctcagac cgtttcagct aaagaatatc ttttccttta tcagaaggaa cggctcaagc
     3901 cattcagaca agtgaaggga cgacaagcca atatttgaaa ccaggtagca gttcttatag
     3961 tcaattgaaa taaaatctga agaaatcgag taggaaactt aaatcaattt ttagcagtgt
     4021 tctattccag attcatactc aatgaaaatt aaagtgcaaa ctaggaagtt agccgcaggc
     4081 tgtacttgag tacggcaagg tgaaactgac gtggtttgaa tttgattttc gaagagtatc
     4141 aatccactat acatattaaa aagtatgggt accaaaacaa aaaaacaggc tctccgaaaa
     4201 ctcggaaagc cttattttaa gctgtttcta gcttcctcac ctttacattt caaggttcgg
     4261 gataaaaggt tcaatggacc tttttattta gcgattgggt aaacagaaac ttgtttttta
     4321 tcgcgtcctt tacgttcaaa gcgtactacg ccttcaactt tagcgaacaa agtatcgtct
     4381 ccaccacgac caacgtttac acctggatag atgtgtgtac cacgttgacg gtaaaggatt
     4441 gatccacctg ttacagtttg tccgtcagct gctttagctc caagacgttt cgcttgtgaa
     4501 tcacgtccgt ttgatgtaga acctccacct tttttgtggg cgaaaagttg caagttgtta
     4561 agagtcattt ttaacataat gttttcctcc gtgttagttt tctgtgataa ctctggtttg
     4621 gacgaactca gaagagttct ccgataagtt tgccatacct aagaaaaatg attcaaagaa
     4681 taactgggtc atttctctct ggtgtgaagg aagatctttt ggtatttcaa ccatcagata
     4741 gccaccttca tcttcgttta attctaggat tggttcatag cctgcaaatt tctcaataga
     4801 attgataaag ttaatggcaa gcgtagaaac cgatgcacac acgacatcta agccgtattc
     4861 gccactctcg gcgtgtccag taatttccgc actcctcagc tcgccatctt cggctctctc
     4921 aaagactgct tgtatcatgt gttctcctta aaattaagcg ttaattgcgt tgatgacaac
     4981 ttttgtatat ggttgacggt gaccttgttt acggtggcta ccttttttag gtttgtactt
     5041 gtaagtaaca actttctttt gttttccttg tttttcaaca gttccaacta cagtagctcc
     5101 agcaacaagt ggagttccga caacagtgtt ttcaccacca acaagaacaa cttcgttaaa
     5161 agtaacttct tgaccagctt caacgttcaa tttttcaatg taaactgctt gaccaacttc
     5221 aactttaact tgttttccgc cagttttgat aattgcgtat gtgctcatta tgcacctcct
     5281 atgattttta tgggtttccc cgattttttt gtgaagactc gcctagcatc gtgggacaaa
     5341 ccacttaaac ttgaataatc aagcaacgat gttcgtgcgg ttgcacagga tcgtgcatag
     5401 tcaactcttc aagtgtagca tatttcctat tttcttacaa gtaataacac ctaaaatcaa
     5461 gctttttctt ttactttttt ctgccactag gcaaaaagca tactgagata aaaaatgctc
     5521 atcataatag gaacaccaag aatggtcttt tcatgataga aaatcgtcaa atagactgaa
     5581 aagacaacgc caaggacaaa actactaagc aggctaacaa atatgaaccc ttcacgcaaa
     5641 aaaggagtgt gcttagttcg gaaataatct ccaaaagcta gcattgttcg tttgatattc
     5701 cctgtcataa aggcattatt gtaggcaata cccgaaacct caccaaaagc agttgtcacc
     5761 agtcccatac agaaggccaa gggcggcact agatagatat tatctacagt ttgtggcaca
     5821 aaaccaataa ttattgatag gattgctaaa ggaatcaagg acagaataga ttttttcaca
     5881 attctcaatt tttccttata aatcgttaat aaaaagactc ccatcataaa cgctattaag
     5941 gttaaaagct tatccctaat atccgaaaca ttattttgta tgagctctac cgaaagaaag
     6001 acaacatttc cagcttgtcc agctacaagg gtattcccgc gaacaataaa agtgtaagca
     6061 tccacatatc cagcacaaaa cgtcaaaaaa gtgctaacct tttagactga cgtgatattt
     6121 ttcttatagg taataacctc attttccctc ccattgtatt ttctcttaga aatattgtac
     6181 cattttcttt ctaaaaaatc gtaggctacc atttagattt tactattagc ataaaaataa
     6241 taatagacaa ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac
     6301 gaacctttag taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat
     6361 tattttaatt tatttctaat cactccttga cataaataac tctcaccaat aaaagactat
     6421 gtcttaaaaa aatggtataa taaaatcaat acttgggctt gatggctatg ctactaataa
     6481 caattaggag agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag
     6541 gaactttaga aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca
     6601 aaaacaaatg gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc
     6661 tcaagatctt gtccaagcaa ccttaactgg cgataagaaa gttgtcagca ttgatttcaa
     6721 tccagctgtc gttgacccag aagaccttga gactctttct gatatgaccg ttcaagccat
     6781 caactctgct cttgaacaaa tcgatgaaac tactaagaaa aaactgggtg ctttcgctgg
     6841 gaaattgcca ttctaaaaac aaggagctag aacaatgctt gtcgataaca aaggctaaga
     6901 aaggtgcaaa aattataaaa aacgcatagt atcaagcaac ctaaaacttt gggctctata
     6961 atatttgtag tgggtaaatc ccctatggat attatggagc ctatttttgt gtagaaaaaa
     7021 agtcccatat gacctataat gaaaagcgac aaaacaactc attagaaaga atcatatgga
     7081 acaattacat tttatcacaa aattactaga cattaaagac cctaatatcc agattttaga
     7141 catcatcaat aaggatacac acaaggaaat catcgccaaa ctggactatg aagctccatc
     7201 ttgtcctgag tgcggaagtc aaatgaagaa atatgacttt caaaaacctt ctaaaattcc
     7261 ttatcttgaa acgactggta tgcctactag aattctcctt agaaagcgtc atttcaagtg
     7321 ctatcactgt tctaaaatga tggtcgctga gacttctatc gtcaagaaga atcatcaaat
     7381 tccttgtatc atcaaccaaa agattgatca gaagctaatt gaaaagactt ctatgaccga
     7441 cattgatcat cagttgtcta tttcaacttc aactgtcatt cgcaagatca atgattttca
     7501 ctttgagcat gatttttcgc gtcttcctga gattatgtcc taggacgttg aaacagtctg
     7561 gggagtgact gtttcaatcg ggagatagag atgagcttta
//
LOCUS       DAVKAU010000069         7208 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVKAU010000069 DAVKAU010000000
VERSION     DAVKAU010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.069"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            459..684
                     /locus_tag="VWX48_001895"
                     /pseudo
     CDS             459..684
                     /locus_tag="VWX48_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(1368..2873)
                     /gene="pyk"
                     /locus_tag="VWX48_001896"
     CDS             complement(1368..2873)
                     /gene="pyk"
                     /locus_tag="VWX48_001896"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU9172460.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(2932..3939)
                     /gene="pfkA"
                     /locus_tag="VWX48_001897"
     CDS             complement(2932..3939)
                     /gene="pfkA"
                     /locus_tag="VWX48_001897"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU9172461.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGATSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            complement(4022..7123)
                     /locus_tag="VWX48_001898"
     CDS             complement(4022..7123)
                     /locus_tag="VWX48_001898"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU9172462.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDISLKLPRFNPARPAVEELRERAELGFVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKSEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
BASE COUNT         2208 a         1583 c         1256 g         2161 t
ORIGIN      
        1 caactataaa acaatataga ctagtaatgg ttggactcaa taagaattgg gtactaagat
       61 aggtataagt aaaaacacca ttagaaatta tgaaaaaagg gttaggtcta ctaagaaaaa
      121 tactatattt gacttagtta aagtattcag tagcttgatc gatgccctct ttcctccagt
      181 tcaaaaggat tctcctagcg atatccaatc tatctacgac caacgggaac cacccagaca
      241 aggtaaagtt ctgacctatg ccgagaggca actgtatgat cagaaaaacg aagtatcgta
      301 aaaatcatca gactggacga ctacagacag actacttact ctcgtgttag gtagtttatc
      361 tctgcaggta gccgctcgat gcaggacaac gatttagata tggagtttcc attatcccag
      421 acgactacga cccaatcgct tatgtcgtca gcaagtccat ggagccaaag ataagaaaca
      481 gcgactacct atttatcaag aataccccac agattgacta taataccatc ggcatcttcc
      541 aagtagacgg cactaactat gtcaagaaac tccgccaagg ctacctcaaa aaaactcaat
      601 cccgaatact ccgacatcca cctagacgaa agcaaccata ttcgtaccat cgggaaagtt
      661 gtcaggctat atagggagaa ttaaaaaagg gggagaatgg cgatataaaa caaacagatt
      721 ttaaaagatt cgaaaaactt tgaaaaagtt tattctacat ttcaaaaaaa gaataagtga
      781 cctaaaatag attagatttt gttaaacaat agtgatatgt aaatttagag aaaggcattt
      841 aagatcactt tgcaaaaggc aaatactaaa ctagagaaac cgataaacca gccccttagt
      901 tcccatattt tcaggcacac actccttagt acactagctg agaagaatgc tataatggtt
      961 agagtagaac acaaaaacgc taaaacagta aataacatct agactcacgt aggtaaaaga
     1021 atggagcaag ctactttgga ggttttaaat accatatcat taaatcgaaa atatatcaga
     1081 tcgaatctag acaagtagat tgcgattgct aaaacatttg tagaaattca tttgactttc
     1141 taatcaattt atgcatatct tatttcatac tcaatgaaaa tcaaagagca aactaggaag
     1201 ctagccgcaa gctgtacttg agtacggtaa ggcgacgctg acgtggtttg aagagatttt
     1261 cgaagagtat caatccatta tgaaagtttt gcctatttct taccctctat acaaaaagcc
     1321 tatcacacaa gctctaaagc tggatatgat aggtttttat atttttctta acgtactgtg
     1381 cggatacgca ttgtgtttgt gcgaacagct tctcctactg gcacaccagc aacgataacg
     1441 atatcatcgc ctgactcaac gagacctgct tctaccgctt tacgttcagc gatttcgaac
     1501 atatcgtcag ttgaagatgg agcatctgtc aacattggga taacacccca gttcaacatc
     1561 aagccacgtt ctgtcaattc gtcaaatgtc aatgctaaga tgtcagcatt tggacggtat
     1621 ttagaaatca aacgtgcagt atgacctgtc ttagtaagag ttacaaccaa tttgatatcc
     1681 attgagctag tagcatcttt aacagcagaa gccattactt ctgtcttaga gttacgctca
     1741 aatgaatctg aatcaagacg tccgtattca ttaagaagag cttgagcgtt cttgtcgatt
     1801 gtagccattg tagttactga ctcgagtggg tatttaccgt ttgcagactc gcctgacaac
     1861 attgtagcgt cagttccgtc gataacagcg ttgaatacgt ctgatacttc tgaacgagtt
     1921 gcacgtggtt tttcagtcat tgtttcaagc atgtttgttg cagtgataac aactttacct
     1981 gcagcattga ctttcttgat aatcattttt tgataaactg gaaccatttc gaacggtact
     2041 tcgataccca tatcaccacg agcaatcata ataccatcag ctgcttcgat gatttcatct
     2101 aagttatcga taccttgttg gttttcgatt ttagcgaaca attgaacatg tccgtttcca
     2161 gtttcttcac agattgcacg aacttcgttc acatcttttg cagtacgtac gaatgaaatt
     2221 gcgatgaagt tgataccttg ttcaagaccg aaacggatat cgtcgttatc gcgttcagca
     2281 agagctggga aaggaatttt agtgttaggg atgttcacac ctttttgttt agcgatgata
     2341 ccatcgtttt caacttcaac ttcaaattca cgagttgcat catctttagc aaccacacga
     2401 agaccaagtt taccatcgtc aaccaaaact tgacgaccaa cttcaacatc atcatagata
     2461 tcaagagcac cagcaacgtt caacgcaatc acttcacgag ttgatttgat tccttgttta
     2521 gttgcaacac gaattttttc accagttttg tatgaatatt ctttagcttc accttcgaac
     2581 aattctgtac ggatttcagg tccttttgta tcaagaagga aaccaacttt tttacctgca
     2641 attttttccg caagtttaac agttgccata cgctcacctt gttcttggtg gtcgccgtgt
     2701 gagaagttga atcggaatgt gttagcacca gcttcaatca atttagcaat gtttttagct
     2761 gaagcttcaa catcaagttt ttcaccccag tatccgtcct caccgaattt tttaccacca
     2821 cggatttcta ccgcaggacc caaagttgca acgattttta cacgtttgtt catgattttt
     2881 gtgactcctt tatatatatg acctttttgg tcttattaac taaattgtaa attatgacaa
     2941 gctcttattc aagctagata gctcaatatc ggctttgtgt gggttgttaa ccacaatctt
     3001 accttctgca gtaaggctaa acaatgcccc ttcttctgca gtaccaagaa ttggattttc
     3061 aaccattttt tcgttacgaa taccaaccgc aacaccaccg ataccttctt taagaagttt
     3121 aacagcatgt gcacccatac gtgacgccaa aacacggtca cgcgcagttg gagaaccacc
     3181 acgttgaata tgtccaagtt ctgttacacg aaggtcgctt gtagctccag cttctttaag
     3241 tttttgacca aattcagccg ctgacatcac accttcagct aagacgatga tattgtgttt
     3301 tttaccacat tcataaccag ctttgatgct tgctacgata tcttccatct tgaagcctgc
     3361 ttcagggatg atgatttcat cagcaccagt tgcaatacca gcccaaagag cgatatcacc
     3421 agcgttacgt cccataactt cgattacaaa agtacgacgg tgacttgatg atgtatcacg
     3481 aatcttatcg atagcgtcca tggcagtagt aaccgctgtg tcaaaaccga ttgtaaagtc
     3541 agtaccaacg atatcgttat cgattgtacc tggaagacca atagctggga agccatgttc
     3601 agtcaaacgc atagcgccgt ggtaagatcc gtcaccaccg ataacaacta caccttcaat
     3661 tccgtgtttt ttcaattgct caatcccttt aagttgccct tcaagttgag cgaactctgg
     3721 gtaacgagct gagtgaagaa aagtaccacc acgagaaatg atgtctccta ctgaagctgc
     3781 atctagggga tgaatttcac cggcaaccat accagcatat ccgtcataga taccaaacac
     3841 ttccattcct tctgaaattg cttgacgaac aactgcacgg atagcagcgt tcataccagg
     3901 tgcgtctccg ccactagtca aaacagcaat acgtttcata ttggtttatg ctcctttttc
     3961 ttttaacatt cttcttgatt atatcacatt tgattttaaa attcttctat tttccgtatt
     4021 tttagcgata aatcgttttc ataacgattt cattcaattt ctcctctaat tcattggatt
     4081 tagctacaaa atgatgggga gaaacgatgg ttttctgttc ctcttcatac cggatgatga
     4141 ctgggattgg gcctttaaat tgttctaaaa tacgtgaaat ttcttgatcc gattcatgat
     4201 ttttcacctg tatccaaaag cgttcagcaa ctgcttctct tatttcttgt gcaatcattt
     4261 gcaaacggcc atcacgtgat tgtatttttc cttttacata gtagaaggct ccctctttta
     4321 tttcctgtcc aacctgacga tataagtctg aaaagagagt gacatccaat tttttcttac
     4381 tatcatctgc ctgtaagaag gccatatttt cacccttttt ggtacgaatc acttttattt
     4441 tctgaacttc aaccaaaata atagcatagc tattttctga caaatttccg attggggtaa
     4501 tcgggtaaat agccttactt gcaatagctt gtagtggatg tttgctgaca cctatcccta
     4561 aaagctcttg ttccatataa aatttttctt gttccgtcca atcttccgat tcctgccaac
     4621 tataaatagc atctccaaac aaacttccca actctttcac aaattcaaat agattagcta
     4681 agttattaaa tactttttga cgattttttt caaatgaatc gaaaagacca acttttacca
     4741 aaggttctag cagaggaagt ttcagataat tctcaggtaa tttagctata aaatcttcaa
     4801 tgttagaata aggtctatgt tcaataatcc aaagcgccaa gtccttgctg agccccttaa
     4861 tcgatttcaa acctatatag atagacttgt tggcaatttt atcgtgatag ggaatagtat
     4921 tgatggatag agaggctact tcaaaacctg cttcaagtgc atctattaag taatcactgt
     4981 tggaataatt taacatgacc tgataaaaaa tggctggata atgcgttttg aaataagcca
     5041 actggaaggc caaggctgag taggcgtagg catgagatct attaaatcca taacctgcaa
     5101 acttctccat aacatcaaaa acctgctctg atttttccgc agtatggcct gcttctatgg
     5161 agccttgaat aaaggaagcc ctcatctcat gcatagcaga ggcatccttt ttacccatag
     5221 ctcgacgcaa aatatcggcc ttcccaagac taaatccagc aaatcgctga gcaacctgca
     5281 taacctgctc ctgatagagc ataatgccat aagttggagc caaaatatcc tccagagctg
     5341 aatctagaac agtcacttct tcctgcccat gcttccttgc cacaaaatta ttgatgtagt
     5401 cacttgcacc tggtcgattt agagaagtag ttgctacgac atcttcaaaa cagactggtt
     5461 gaacacgttt gagcaagcga atggcaccag gttgctcaaa ttgaaagata ccttttgtat
     5521 ttccagaggc aaataaatct aacgtttctt tgtcttccaa atctatttct tcaattttaa
     5581 ggtgaatacc ttctgtttca gcaagcaact cttgcatctt ctggacaaag gtcaaatttc
     5641 gtagtcccag aaagtccatc ttcaaaagtc cgctagcctc aactccatga gcatcatact
     5701 gagtcagtgg aatttcatca ccatacttta gaggaatgta gttggttaaa tcttggtcac
     5761 taattacaac accagccgca tggacagagg tttgccttgg atagccctct atcttgcaag
     5821 caatctcaaa agctttttgg tattctaact tactattgat ttgctgacga aactggagat
     5881 tgccctcata ggccgactta agattgtcac gaaaactgat tttcttagta attgcagata
     5941 attcatactc tggcacacca aagcgtttca agacatctcg aagagcttgc ttggctccaa
     6001 aggttgaaaa agtaacgatt tgtgccgcat gtttactacc atatttatta ccaacatatc
     6061 tgataaaatc tggacgataa atatctggga tatcaatatc aatatcaggc atggtatagc
     6121 gttcacgatt aagaaagcgt tcaaaaatca gatttttctc tactgggtca atccccgtga
     6181 tgtctaaggc ataagaaacc aaactgccta ctgcagaacc ccttcccatt cccatataat
     6241 agccattcga tcgtccaaaa cgcaacaaat cccaaacaac caagaaataa tcatcaaagc
     6301 ccatatcatg aataacagac aattcttggt ctagtctatc ttgatattct ttactagtca
     6361 accccttctg aacaaacccc agttcagcac gctctctcaa ctcctctact gctggtctag
     6421 ctggattaaa acgaggcagt ttcagactaa tatccaagtc gtaagaaatg cctgaaataa
     6481 gcttttctaa attgtccaaa gcttgcggaa aacgctcttg gaatagtttc tctaaagaac
     6541 ttgctgatat aaagacatct tgtctcgaac gcaagggaac ttctctgagc ggtagatttt
     6601 ctttaatcgc tgttaaaact tgaagaactt ctctatccct gctttcaaaa gcgttgaccc
     6661 gataaagagg taagatagga tgatgaaatt cgcttgctag tgtttctgga taaaccccta
     6721 tatagtaatc acagcctagt tctaacgact caactctatc aaaataaggc acaatgaccg
     6781 cgatatcctc caggtactgg gacaggactg accaagtttt ctccccctgc atcttggctg
     6841 tcgaaagctt catcaactgc tgatagccca cactagatag agctaaaaag cgcaaattca
     6901 cttcctgatc atctacaaac actgtcattt caagccctag caaaggatga atgccgtatt
     6961 tttttgtaat ctctagaaag tcgaaagcgc cataaagatt gtcaatatcc atcatagcca
     7021 aatgagtgta gccgtattct ttagctgctc tcacatactt ttcgatcgaa atgacgcttt
     7081 ccataaaact atagactgtt tttgtatcta gttgtgcgat caatttacac ttctcctcta
     7141 tccttctcac tatattatac cattttcacc tataaatggc ttctcttgag aaaaatttca
     7201 tcagctta
//
LOCUS       DAVKAU010000070         7137 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVKAU010000070 DAVKAU010000000
VERSION     DAVKAU010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.070"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..264
                     /locus_tag="VWX48_001899"
     CDS             <1..264
                     /locus_tag="VWX48_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9172463.1"
                     /translation="VILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKI
                     LLPLPPLALQNEFADFVALVDKSQFACEIAIKVWRNSLKFSII"
     gene            369..3645
                     /locus_tag="VWX48_001900"
                     /pseudo
     CDS             369..3645
                     /locus_tag="VWX48_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562199.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            3916..4116
                     /locus_tag="VWX48_001901"
     CDS             3916..4116
                     /locus_tag="VWX48_001901"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172464.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(4210..4680)
                     /locus_tag="VWX48_001902"
     CDS             complement(4210..4680)
                     /locus_tag="VWX48_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9172465.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4697..6970)
                     /locus_tag="VWX48_001903"
     CDS             complement(4697..6970)
                     /locus_tag="VWX48_001903"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU9172466.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT         2210 a         1205 c         1531 g         2191 t
ORIGIN      
        1 gtaatattac gtcccaagac accaaatcta aatcagaaat ttattatcca tgttttaagg
       61 aataataatt atagtcgagt gatatcagga agtgctcagc ctcagttacc aattacaaaa
      121 ttaaaaaaaa tacttctccc ccttccccca ctagccctcc aaaatgagtt cgcagacttt
      181 gtagccctgg tcgacaaatc acaatttgct tgtgagatag ctataaaagt gtggagaaat
      241 agcttgaaat ttagtataat atagctaaac tatttgttta aagtgagaaa aaaatgggaa
      301 attttagctt tcttttaaaa aatgacgaat atgaatcttt ttcaaaacct tgaattgaag
      361 ctgagaatat gattgctaca tcaactgtgg ctactgcctt tatggcgcgt cgtgctttag
      421 agcaggctgt ccattggata tatagtcacg attcatattt agaagctccc tatcgtgcta
      481 ctctatcttc tttagtatgg gatgatgatt ttagggatat cgtagattct gaactccaca
      541 agcagatagt tctgttgatt cggtggggaa accatgctgc tcatggtggt gaaattaagg
      601 aacgagaagc gattttagct ttgcatcatt tgtatcagtt tgttaatttt atcgattatt
      661 gttacagcaa tgagtttgtg gagcgttatt ttgatgagaa gtgcttacca ctttcagcaa
      721 acatcaaata ccgagaaact ccacaatcta tgataaagtt acaagacagt ttaccagaac
      781 tgcctgattt tcatgaacag atggctgctc agtccgtaga agttcaagag acttatactg
      841 aaaaacgtga gactgcagcg caacggcaag atgtgccttt ccatattgat caattgtctg
      901 aggcagagac aagaaagctc tttattgata tcgatctccg tttagcagga tggatatttg
      961 aagaaaactg tcgtgttgag atagccgttg atggtctcaa gcacggttca ggaattggtt
     1021 actgtgacta tgtactttat ggtaaaaatg ggaaaatttt agcgattgta gaggctaaaa
     1081 aagcctctgt caatccagaa gtaggggaag tacaggtcaa agaatatgct gaagctttgg
     1141 agaaacatat cggctatcag ccaatttgct ttattacaaa tgggttgaag cactatatac
     1201 ttgatggtcc gaaccgccgc cagattgcag gcttttactc tcaagaagaa ttgcaattag
     1261 tgatggatag acgtcatctt caaaaaccgc ttgaggatat ttctagtaaa attagggacg
     1321 atatttccgg gcgtcactac caaaaacatg ccattgcaag cgtttgtgaa gctttctcta
     1381 atcatcgtag acaggcactt ttggttatgg caactggggc ggggaaaact cgtacagcag
     1441 tttctctagt tgatatctta tcacgtcata actgggtaaa aaacgttctc ttcttagccg
     1501 atagaacttc cttggttaag caagcctatg attcgtttag aaaattactc ccagatcttt
     1561 ccgtttgtaa cttcttagaa gataaagaag gagctcaatc aagtcgtatg gtcttttcaa
     1621 cttatccgac catgattgga gcgattagtg gtcaagaaga agtaaatcaa cgccctttta
     1681 ctgttgggca ttttgacctt atcataattg acgaatctca ccgttctatt tatcagaaat
     1741 acaagtccat ttttgattat tttgatgcaa gaattgtagg cttaacagct actccgcgtc
     1801 aagatttaga taaaaacacc tatggattct ttaatttgga gaatggggtt ccaacatatg
     1861 catatgattt gaaagaggct gttaaagacg gatatttagt agcctatcat tctatcgaaa
     1921 tcaaactgaa actacctacg gatggtctac attatgatga tttgtccgaa gaagaaaagg
     1981 aacattttga tagcaaattt gaagacgata gctgtgaaaa agatattgat gggagtgtat
     2041 ttaattcctt tattttcaat aaaagtacag tagaaattgt tttaaatgaa ctcatgacaa
     2101 gaggaattca gacagcctcg ggtgatgaaa ttggtaaaac tattattttt gctaaaaatc
     2161 atgatcatgc ggaatatatc agaggtattt ttaacaaccg ctatcctgaa aaagggagcg
     2221 actatgctca ggtgattgat tatagtatta agcattatca gaccttgatt gatgatttta
     2281 aaattaagga gaagtatcct caaattgcga tttctgtcga tatgttagat acaggtattg
     2341 atgtaccaga ggttgttaat ttagtcttct tcaagaaagt acgctctaaa actaagtttt
     2401 ggcagatgat tggtcgagga acccgtctat gtaaagattt atttggacct gagcaggata
     2461 aggaaaactt cttggtattt gattatgggg ataattttga ttattttcgt gcagatccaa
     2521 gagatggaga agggtcgtca cattgtttcg ttgactcagc gtttatttaa tatcaaagtg
     2581 gacttgattc gagaacttca gggactccaa taccaagaag atcagtttgc gagagcatac
     2641 cgtcagcagc ttgtctcgga acttcaaggt cgtatagaga gcttaaatga gttggacttc
     2701 agggttcgta tggttttaga tacagtttat agctatagga aattggaaag ttggcagaat
     2761 ctaactgctg ttacaagtga aaccattcaa aaaaatctct ctccgctttt atttgatgaa
     2821 gataaagaag atgagatggc gaggagattt gatttgtggt tgcttcatat tcagttgggg
     2881 caactgacag ctaaatcttc cactgttcat atttcccaag tgatgaagac ggctagagct
     2941 ctttctgcta ttggcaatat cccgcaggtt tttgagcagg ctgaaattat caggaaagta
     3001 caggagcctg aattttggaa agaagttaac ttgtctgatt tggaaaaaat tcgtcttgct
     3061 attcgagatt tattacagtt tttggataaa acagaccgta aaccctacta tgttaacttt
     3121 gaagatcgta tactctccac tgttcacgag accacagcat ttttgcaggt caacgatctt
     3181 cggtcttaca atgaaaaagt tgagcattat ttgaaaactc atctggatga ggagtccatt
     3241 tctaagctat accataataa aaagttgaca tctgatgata tgcttgcact tgaaaaattg
     3301 ctctgggaaa aattaggtag taaagcagac taccaaagtc attatgaaaa taaggcaatt
     3361 ccgagattgg ttcgtgagat tattggctta gatagagagt ctgccaatcg tattttttct
     3421 aaatttttgt cggatgagaa tcttaatgcc aggcagattt catttgtaaa attgattgta
     3481 gactacattg tagaaaatgg ttttttagag acgaaagtgt taacgcaaga gccgtttaaa
     3541 tcttatggtt ctgttcaact actcttccaa caccaactac cagtacttcg taatattgtt
     3601 caaatcattg aacttatcaa taatcgagct ggagaagcgg cttaaattct aaagtgattg
     3661 ccatgctgag actcatttaa aattaaaaag agtagaaatt tatgctatat atgagaagtt
     3721 ttattaggaa gaatgtcatc gttttcctag aatacagtat cagttgttaa gtggttgata
     3781 aatttcaaag tagatacttg taccacgatg tttgttgatc gagttattaa caaaagagct
     3841 actttgattt taaagaaata gaaaacaaaa agctgagcaa gaattcaatt gcaggagaaa
     3901 atgaaataat actcaatgaa aatcaaagag caaactagga aactagctgc aggctgctca
     3961 aaacactgtt ttgaggttgt agataagact gacgaagtca gctcaaaaca tggttttgag
     4021 gttgtagatg aaactgacga agtcagtaac catacctacg gcaaggcgac gttgacgcgg
     4081 attgaagaga ttttcgaaga gtataaatct tcctaggata gagcaaaacg catagtatca
     4141 agggttttct gatgttaaag actttctacc aggtttttta aaagcataat tgttagttgt
     4201 agtcatttat tattcttcaa agaaaaatgg tggggcgaat tttttcagtt cttcaaagca
     4261 cttttgagca gtatctgcat cttcacagat gataagacag acatcattac cacaaagggt
     4321 agcgatagcg tcagggaagc tcaaagtatc aatgatagaa ccaaaggatt gagccagtcc
     4381 aggaagggtt tttagtagga cttggtgttg aactgggcgc atccagacaa gggcgtcttc
     4441 catgtagagt tcgagacgtt tttcccattt tgagatggaa ccattgttaa gaacataata
     4501 agcgctatct tcttcgcgga cttttgatag gttcatattt ttgatgtcgc gtgagagggt
     4561 tgcctgggtt acttgaatgt cgttctcagc aagaagggct tgcaactcag cctgtgtatg
     4621 aatcttgttt tttgtgataa gagcgcgtat aagttggtgg cggtgttctg atttattcat
     4681 aataatgtaa ctccttttag caaggtaagg taagcatgga ctgagcgagg tcgacagtca
     4741 agtggtagtc tgtattgtca cggatggtga tttcaaagtc agtagtatag aggactaaac
     4801 ggagagtgtc tccttctttt agcttgtaaa tagttggctg cagttcaaat tgaacgtcca
     4861 tccattcatc tgcagtaata tcctctacta acagtaaatc atttctattt tgtaaattaa
     4921 ggtaaccttt tgtcacgact cgttgtgcct ctggtctaaa tggcaattca cagagatttt
     4981 ccaacatgtg atagcgaccg ttatcaatgg ttctagcact taaaatagct ggataaggtt
     5041 gtaggtattt cttttgccca aattctagca gttgggcaga taagagcccc ttgtttgtac
     5101 tggatttgat acgaagattg agctgagcgc gaccgtttag gtggagatct ttagtcacag
     5161 gaaggttaat agtaatctga ttggctttcc cttgatagag ctctgtattg aaggtttggt
     5221 atgtcttacc atagcgctca aaatccttat ctgggtactg gttttgaata gcttgctctt
     5281 cttgaccaag tgagaaggtt tcacagtttt cttgcccacc gaagttatca agtgataacc
     5341 aagtctgtgg agctgtattg tcctgccaga taacagtagg aagttgaaag tctgtttcct
     5401 gtcctagtaa tttcttggtc aataaggcat ttatggactc acggaagtca attgattgcc
     5461 aattgttcat gtaaacatga gcaccattat ggaaaaagag atgcttgtgt atatgagtag
     5521 gaagagcatg gaacatctgg taaacatgaa gtggtttgac attccaatcc tgagaaccat
     5581 gagtaaagac aacctctgcc tttactttat gggcattgag cagataattg cggtcatgcc
     5641 aaaactgatt gtagtcccca gtttttcggt ctagctgagc tttcactttt tctaagtcag
     5701 cttggtgagc ttcattgcca cggatatagt cgccagctaa gagattacga gaataggtta
     5761 actcagcaag ggagtcaaag tcctcacctg gataaccacc tgggctagtc accagaccgt
     5821 tttcacggta gtagttgtac catgatgaaa ttcctgcctc ggcaatgata acttctaaac
     5881 catcgactcc tgtagtcgca agaccattgg acatggtacc tagataggaa agtcctgttg
     5941 tagcaacttt tccgtttgac caatcagcct tgacttgacg ctggcgcgtg tgatcagtaa
     6001 aggcacggca acggccgtta agccaatcga tgacattttt ataagcctcg atttgctggt
     6061 agtctccatt agtcatgaaa cctgtcgagt ctttggtacc aacacctgag acatagagat
     6121 tggcaaagcc tctcggaagg aagtagtcgt ttagtgtata gctagagttg atgtgagtta
     6181 gcttttcctc agcctctgct ataagctcag ctttaccttg gggttggacg agatttagtt
     6241 gaggtttctc tagctcaatc ttgtgaggaa gcttaacctc aagctcgccc tccatcttgt
     6301 agagagcctt gtcactagcc ttgtcattgg ttccctgatg ataagggctg gctgtcatga
     6361 tggcagggat ttttccatca aaacgagggc gaataatgct aacctttact aggtctgata
     6421 gccctttttg gtcagtatcg acacgagact caacgtaaac gacttcacga atgacatcct
     6481 ggttagaaaa agtagccaaa ctcttgccgt taaagtagtg gtagtcatta tcctccggaa
     6541 taagaccatc actaacaagt tggtcgataa gagtatttcc ttttttggtg cgagtattga
     6601 gtaactgata gagattttca atcaagtcac catatataat gggaaatcca gtttctttac
     6661 gaaaaacgtc actatcttcg aagtcaacca aataagaaaa gcctaaaagt tgaaaagcaa
     6721 cagtataaaa aatatctgct gtcagttcat cttctgattg aaaaaatgtc agcaggtctg
     6781 tttttttatc agctgctagg atagaaagtg ggtagttggt gtcttgataa gtgaaaaaga
     6841 aacgacgtaa aaaggtttca agtgagtctt tgtgattggc tgtattttgt aaatcaaagc
     6901 cacatttttt tagttcagat aagacatttt cttttggaaa attgatataa ctatattgat
     6961 taaaacgcat agaacctcca tatagaatga cagttaaggt tattatatca aaaaaaaagc
     7021 agaaagggaa ttgttaactt caaaaggaaa taatccaata aaaatgaata aagtactaaa
     7081 ttcaatatag agaacagagt aacaataaga ataaatagat agggtataaa agttcta
//
LOCUS       DAVKAU010000071         6805 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVKAU010000071 DAVKAU010000000
VERSION     DAVKAU010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.071"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(43..252)
                     /locus_tag="VWX48_001904"
                     /pseudo
     CDS             complement(43..252)
                     /locus_tag="VWX48_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            311..493
                     /locus_tag="VWX48_001905"
     CDS             311..493
                     /locus_tag="VWX48_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9172467.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
     gene            794..1633
                     /locus_tag="VWX48_001906"
     CDS             794..1633
                     /locus_tag="VWX48_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU9172468.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1651..3489
                     /locus_tag="VWX48_001907"
     CDS             1651..3489
                     /locus_tag="VWX48_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9172469.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTLAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3502..4917
                     /locus_tag="VWX48_001908"
     CDS             3502..4917
                     /locus_tag="VWX48_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9172470.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLKRYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            5215..6561
                     /locus_tag="VWX48_001909"
     CDS             5215..6561
                     /locus_tag="VWX48_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU9172471.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     QISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT         2229 a         1042 c         1302 g         2232 t
ORIGIN      
        1 gtattcaaga gaaactctat ctttagtcca gccttcatgt cagactttat gaatcatttc
       61 ttgttttaaa tcaggagaat agtaacgatt ttttcctttt ttgacgaact ctattccgta
      121 acgatcaatc aatttaatca tgtacctaag attagaattg tttatcccaa atttatttga
      181 aagcttctct aagctatatc cttgttttct aagttcatag atctgaactt tatcatcata
      241 agttagtttc atactaaaac accccaaaag ttagattttt tctgtctaac ttttggggtg
      301 cagttcacag ttgaagagcc agaaaattaa agtgtctttt actcaatcaa aaatagtaac
      361 gcctattctt ttggtgaata agactattgt ttggtatggt gcaatgccat tattagggaa
      421 ggtagatgag atgaccatat tacgtttgga atcagctagt atagcttctg aactagtggc
      481 aggtttacga tagagaaaat ttttaaaaat ttctatgtat gattttcatt tctttagtga
      541 gactgttgcc attatcacat tcgaatcaca caaaataaaa aaatttttat aagtacttga
      601 caaatagatt gaaatatcat aaaataaaaa cggttacaga gttattaatt atttaagctt
      661 catgtcacca ttaaaaattg aaataaaagg atgttatcac taatacaagt gagcaggaac
      721 ctatttaatc acatcagaag aagtttcttg atgtttttta agtaggttcc ttttatttta
      781 aaagggaaat tttatgatca taaaacgaat actaaaccac aatgccgtaa ttgcgcaaag
      841 taaaaaagat atcgatattc ttctttttgg aaggggaata gcttttggaa gaaaaattgg
      901 agataaagta aatccaattg atattgagaa aagttttttt ctcaaaaata gagataatat
      961 gacccgtttt acagagatgt ttattaacgt tcctttggag ttggtgtaca tcaccgaaaa
     1021 aataattaat ctaggtaaaa taacattagg taataatttt gatgagatta tctatataaa
     1081 tctaacggat catatttctt cgagtataga acgttataaa gaaggagtta ttatttcgaa
     1141 tcccctacgc tgggaaatat cgaaatatta taaagaagaa tttgagcttg ggaaaagggc
     1201 tttacaaata ataaaaaaag agttaggtat tgaacttcca attgacgaag ctgcattcat
     1261 agcgctacat tttgttaatg ctaatttaga aaataatttt caagagtcgt ataaaatcac
     1321 tgaaataatt atgggaattg agaaaatcat tcaagatttc tattgtactg agtttaacca
     1381 agattctatt gattattata gattcataac tcatataaaa ttatttgccc atcgcttggt
     1441 tgaaaataca acttattgtg acgatgatga tgaagacttg ttagcattaa tgaaaaataa
     1501 atatcctaga gaatatgaat gtggtgaaca ggtggcaatg tttatacaaa ctgagtacaa
     1561 ttatttgctg acttctagtg aattagttta tttgatggct catattcgtc gcttaacaaa
     1621 aaatttagat taatagaata ggagaatacc atgagttata aagatacggt acaaaaaatc
     1681 ctcgatgtaa ttggaggtga aaaaaatgtc aatagagtta cccattgtgt aacacgttta
     1741 agattagaat taaaagatga aaatttagtc aatgatgatg atgtgaagaa gataccaggt
     1801 gtaataggta ttatgaaaaa gaatggacaa tatcaaatta tacttggtaa tgatgtagct
     1861 aattattata aagaattcgt taaacttggc aattttgaat ccgattcagt tgttcaaggg
     1921 cacaaaggga atattttaga aagaatcatt gagtatatcg ctggttccat gactccaatc
     1981 attccagcaa tgttaggggg aggtatgttg aaagtcttgg taatcatttt accaatgctt
     2041 ggtatattgc aatcagattc tcagactatt gcttttttga cattttttgg ggatgctcca
     2101 tattatttct taccgctgtt attagcttat tctgcatcac aaaaattaaa agtaacatct
     2161 acattagcta tgtctgtagc aggtgtactt ctccatccaa attttgttca aatggtgcaa
     2221 tcagggaatc ctcttagttt atttggtgca cctgtgacac cagctagtta tggttcatca
     2281 gtcgttccaa ttcttattat ggtttggttg atgaaatata ttgaaaaaat aattgctaaa
     2341 ttaacactag ctattactaa gagttttttg caacctacgc tagtattatt agtatcaagc
     2401 tgtattgcct tagttgtagt cggacctatt ggagtaattg ttggtgaagg attatcaaat
     2461 ctagttgggc aaatgtatgg tgtagctgga tggcttacat tagctattct tggtgctatt
     2521 atgccattta ttgttatgac tggaatgcat tgggcttttg cacctatttt tttggcggca
     2581 tctattgcta ctccagacgt attaattctt ccagcaatgt tagggtcaaa cttagctcaa
     2641 ggggctgctt cgatggctgt tgcattaaag agtaaaaata ataatacaaa acaaattgct
     2701 tttgcagcag gtttctcagc cttacttgca gggattaccg aacctgcatt atatggtgtg
     2761 actttaaaat ataaaaaacc gctttatgca gctatgattg gtggtggatt agcgggatta
     2821 tttgcaggtc ttactagtgt taaagcatat ctatttgctg tcccatcttt gatagcgttg
     2881 cctcaattta tttattctga tgtgccatca aatattgtaa atgctttaat tgtggcggtc
     2941 atttcggttg ttattacctt tgtattagct tatatatttg gaatcgatga agaagagagt
     3001 tctagcaatt tagaagttga agctggagtt tcaaataaaa aaatgatatt ttctcctata
     3061 tcaggagaaa tcattccgtt aagcgatgtc caggataaaa cattttcaga taaactaatt
     3121 ggagacggag tagcgattat cccaagtgaa ggtaaggttt atgcaccatt tgatgggaaa
     3181 attacaaata tttttccgac taagcacgca attggattga agagtgatga gggtgttgag
     3241 ttactaattc atattggatt agatactgtt gagctaaaag gtcaaggttt tattagtcat
     3301 gtagaagaag gagacagagt tttcaaaaat cagttgattt ttgaaatgga cttgaattta
     3361 atcaagacta aaggctacga aacagttaca ccagtaattg taacgaatac caatgatttt
     3421 ctagatgtat tagtattacc taataatcag acaatcgagc attctaagga attactggta
     3481 atattataat ggaggaaagt tatgaccatt tttccagatg attttctttg gggtggagct
     3541 gttgcagcta atcaagtaga gggagcatat aatgaagatg gtaagggctt atcagttcag
     3601 gatgtgttac ccaaaggtgg attaggagaa gcaacagaaa atcctacaga agataactta
     3661 aaattgatag gtattgattt ttatcataaa tataaggaag atatatcctt gttttctgaa
     3721 atgggcttta atgtttttcg tacttctatt gcatggagta gaatttttcc aaaaggagat
     3781 gaggaagaac ctaacgaagc tggtttgaaa tattatgatg aattatttga tgaactacat
     3841 gctcacggga tagaaccact tgtaactctt tcacactatg agactccatt atatttagca
     3901 agaaaatatc atggatggat tgataggaga atgattcatt tttatgaaaa atttgctcga
     3961 acagttttaa aaaggtataa agataaagtt aaatattggc ttacatttaa cgaagtaaac
     4021 tctgttttgg aattaccgtt tactagtgga ggaatagata tacctaagga gaatctttcg
     4081 aaacaagaat tatatcaagc tatacatcat gaattagtcg cctcgagttt ggttacaaaa
     4141 attgctcgtg agattaattc agagtttaag gtggggtgta tggtattagc tatgccagct
     4201 tatccaatga ctccaaatcc aaaagatgta tgggcgactc atgagtatga gaatctaaat
     4261 tatctatttt cagatgtgca tgttagaggt tattatccga attatgcaaa aagatatttt
     4321 aaggaacatg acattaacat agagtttgca gctgaagatg cagagttatt aaaaaattat
     4381 accgtagatt ttttatcctt tagctattac atgagtgtga ctcaatctgc tcttccaaca
     4441 cagtataatt caggagaagg gaatattatt ggtggcttag taaatcctta tttagagtct
     4501 tctgagtggg gatggcaaat tgatccaatt ggactacgta taattttaaa tagatattat
     4561 gaccgttatc aaattccatt atttatagtg gaaaacggat taggtgctaa agatcaacta
     4621 ataaaagatg aatttaataa cttaacagtc caagatgatt atagaattca gtatatgaaa
     4681 gaacatttat tgcaagtagc tgaagctcta caagatggtg tggaaattat gggctatacg
     4741 tcttggggat gtattgactg tgtttctatg tccactgcac aactttctaa aaggtacggt
     4801 ctcatttatg ttgatcgaaa cgatgatgga agtggtacat taaatcgata taagaaaatg
     4861 tcttttactt ggtataaaga agtgattgaa tcaaatggag aatccttatt caaatagttt
     4921 tttattgatg actagctatt atcacggtta aggcagcatt tcattaaata tggaataaag
     4981 aagtttggaa gacattaaat tctaaacttc tttattttat agggggatta attaatttaa
     5041 ttttgttacc cccaattatt cacccctaat ctaaaaacca tccagaatcc ttgccttagc
     5101 ttagatcctg gatggtttct tttttcaccc aatgggtgtt ttttactaga caaaaaagag
     5161 tttccccttt atggtataag tgtagaaaaa aacacaaaaa gaaaggaaac tcacatgaac
     5221 agtttaccaa atcatcactt ccaaaacaag tctttttacc aactatcttt cgatggaggt
     5281 catttaaccc agtatggtgg tcttatcttt tttcaggaac ttttttccca gttgaaacta
     5341 aaagagcaga tttctaagta tttagtaacg aatgaccaac gccgctactg tcgttattcg
     5401 gattcagata tccttgtcca gttcctcttt caactgttaa caggctatgg aacggactat
     5461 gcttgtaaag aattgtcagc tgatgcctac tttccaaaat tgttggaagg agggcagctt
     5521 gcttcacagc caaccttatc ccgttttctt tccagaactg acgaggaaac agtccatagt
     5581 ttgcgatgcc tcaaccttga attggtcgaa ttctttttac agtttcacca gctaaaccaa
     5641 ctcattgtag atatcgattc tacccatttc acaacttatg gcaagcaaga aggtgttgct
     5701 tataacgctc actatcgtgc tcatggctat catcctcttt atgctttcga ggggaagaca
     5761 ggttattgtt tcaatgctca gcttcgtcct ggtaatcgtt attgttctga agaggcagac
     5821 agctttatca cacctgtttt agaacggttt aatcaacttc tctttcgaat ggatagtggc
     5881 tttgcgaccc ccaaattata cgatttaatt gaaaaaacag ggcaatacta cctcataaaa
     5941 ctcaagaaaa atactgttct gagccgtctt ggagaccttt ccctcccttg cccacaggat
     6001 gaggacttaa ccatcttgcc ccactccgcc tactcagaaa ctctctatca agcaggatct
     6061 tggtcgcaca agcgtcgtgt ctgccagttc tctgaacgaa aagaaggaaa cttgttctac
     6121 gatgttattt ctctcgttac aaatatgacg agtggaacaa gccaagacca gtttcagctt
     6181 tatcgtggac gtggtcaagc cgagaatttc atcaaggaga tgaaggaggg attttttggc
     6241 gataaaacgg atagttcaac cttaatcaaa aacgaagttc gtatgatgat gagctgtatc
     6301 gcctacaatc tctatctttt tctcaaacat ctagctggag gtgacttcca aactttaaca
     6361 atcaaacgct tccgccatct ttttcttcac gtggtaggaa aatgtgttcg aacaggacgc
     6421 aagcagctcc tcaaattgtc tagtctctat gcctattccg aattgttttc agcactttat
     6481 tctaggatta gaaaagtcaa cctgaatctt cctgttcctt atgaaccacc tagaagaaaa
     6541 gcgtcgttaa tgatgcatta aagaacagtc gagatgaaaa aatcgtgtga cgcaccaagg
     6601 gaggagtctg cccttttgag gaaatctagc gaggaaaaac gatactggaa cagcagaaag
     6661 taaaactgac ctcatgagga ggaagaaagt ggctcatgag gtcaggggtt ttgtaagtta
     6721 catctagttg agagaggtat gaatgatttg gggttacaga gagccgatta taaatagtta
     6781 acttaggata gattggttat atata
//
LOCUS       DAVKAU010000072         6264 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVKAU010000072 DAVKAU010000000
VERSION     DAVKAU010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6264
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.072"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(297..1523)
                     /locus_tag="VWX48_001910"
     CDS             complement(297..1523)
                     /locus_tag="VWX48_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9172472.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLVSDTLSAFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1595..2260)
                     /locus_tag="VWX48_001911"
     CDS             complement(1595..2260)
                     /locus_tag="VWX48_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9172473.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2328..2525)
                     /locus_tag="VWX48_001912"
     CDS             complement(2328..2525)
                     /locus_tag="VWX48_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEU9172474.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            complement(2816..3680)
                     /locus_tag="VWX48_001913"
                     /pseudo
     CDS             complement(2816..3680)
                     /locus_tag="VWX48_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
     gene            complement(4075..5247)
                     /locus_tag="VWX48_001914"
     CDS             complement(4075..5247)
                     /locus_tag="VWX48_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU9172475.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            complement(5260..6008)
                     /locus_tag="VWX48_001915"
                     /pseudo
     CDS             complement(5260..6008)
                     /locus_tag="VWX48_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
     gene            complement(6020..>6264)
                     /locus_tag="VWX48_001916"
     CDS             complement(6020..>6264)
                     /locus_tag="VWX48_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172476.1"
                     /translation="FRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIERILK
                     YLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
BASE COUNT         2182 a         1170 c          964 g         1948 t
ORIGIN      
        1 aacatatata cggcaaagtg aagctgacgt ggtttgaaga gagtttcgaa gagtataagt
       61 aggctgaaaa gaatccagcc acagcatgga ctattatata gcagattgaa ataagatgag
      121 aacaaatcga ttgggaaagt aaaattaatt tctataaatg ttttagcaat tgtttcgtac
      181 tattttagat tcagtctatt ataacacatt cagaaaagag aaaaaagtct gttgattttg
      241 accatcataa aaagactggc aatccagtct caaacatata ttatagaaat tctccactaa
      301 atactttcac gaatattcag aagcatgaca aaggcaacta gaagaaatag caataaaaca
      361 aagctaactg ccagagttcc aaagctagta gcaatggtta ccaaagctat tgtaaataag
      421 ctaggtaaaa caaccgtaat ggcactgata gaagattgaa ctgctcccat tgactcctca
      481 ggtatttgtt taaaaacgag ttcttgcaat ctaggagaga gaacacctgc gaaaaaggca
      541 tccaaggtac taaagatgag aatccagtca aaacgaactg tggcaaatcc tactagaaga
      601 agcaactgga tgacaagtga ggcatagaga gctgttttta tggaaatggt atgttgcaga
      661 tagccactta caaggcttcc gacaatcagg gctgacagtt caaaagtgga tagcaaggca
      721 agagattgac ctgtttgtaa attcaaaaag ggttgattcc tcaaaaatag agtagagaca
      781 ggaaccgtaa catttatcac tgcttgacta gtagagataa taaacaaaac caagagcacc
      841 ttattcatat tccatatcaa tttcgatgat tggagcaaat gctggcaaaa ggattttaca
      901 gagagtcctt cttgatagct aatcgttttt tctactttca agaggtcagt ttttatgaag
      961 aggataccta aaaatgcgat taaaaaggta agagcgttca gtaaggaaat aaactggatg
     1021 gatagaatgc ctagtaagac tcctcctagg atattactga ttgttttcac taaactaaca
     1081 gttgactgtt taaatccaat agcttctgcc agatggtctt gcccaataat tctaatgaaa
     1141 atcggagtga gcatggcgcc tgaaaaagca ctcaatgtat cagacacgag gttaagcaga
     1201 caaataaagg ttactagcaa caaggaaaaa gactgccctg aaagcgatag ggacactata
     1261 gagtaaagca aaaattttgt aaaactaatg actgtgtatt tcaagacacg atgatgttga
     1321 aaatctgcca aaactcccag aaagatttgt aaaatttggg gaagggtttc tgaaatcgta
     1381 atgagtaaaa tcgccaaagg tgcaaaagac gcatctgcca cataattcag aaaggccaga
     1441 taaaaaatcg tatccccaag cgttgaaatc cactggttga tagttaattg cctaaaatct
     1501 ctattttgaa gaaatacttt catcacaact ccttcttaag ttcaaatggg aatctttccc
     1561 cagaaataga ccgcgatact actaacaacc aaaattacag taacatcaaa agctgaccaa
     1621 tgccgttgta gactatatgc agtccaatag gccaataaat tgactttgtc attctaaata
     1681 agactgcaaa tataagacct ccacccatat agaagacaaa gtctgtcaag acccaaccgt
     1741 gattactaat gtgcgagacc ccaaataaaa cagcggaacc aagtacatct agcccccatt
     1801 tctttccttt ttccagagca gtcatcacta atccacgata aatcatgtct tcaaaaatgg
     1861 gacctgcaat cacaggataa aaaaaataca tcaaaaatgc cgtagctcct gtaaaagtag
     1921 gagcagcatg ttgataagaa atttcatttc gagtaggtgg gaaaagaaaa aaggtgacaa
     1981 aattccaagc aacaaaagca agcagagcta ggaaggaata gaaaagatag gatcctttaa
     2041 actttctact attgattttc tgccatttcc ccgaccaaat catagcaata agagcaaata
     2101 aaaccacaag aaaattcaac atcatatccg acagataata ggcaaagtca gatagcccag
     2161 caacaaggtc gctgcgtaaa actaaaacac tgaacttctg gtcagcaata actagtagaa
     2221 aaactataat aaagtagcgg tgtgagatta tctttttcat tctattttct cctatactat
     2281 gaaataaaga cagtccctac ccaagaaaaa ggcaaggact ctgaatatca ataatggcga
     2341 cgattaacag tggaagaatc atggttaaaa tatttcttcc agaaattagt gattgaccaa
     2401 gacgttccta aacctcccca agcaccggct gggataacag cattattccc aaattcccct
     2461 ccataaactg tctccaactc agcttctgtc aattccattg tttctgcaaa ttgtaaattt
     2521 aacatctttt acactccttc aattatcttc atttgtaaac cacttctgcg acctaggatt
     2581 tgcttcaagt gctttacaag tacagtataa cacgaaaatt ggcttatttt aaaaaatcgc
     2641 atatttgata ttttttctta tagaaatttc ttatttgcga ttttgataga tttgattatt
     2701 tccctggtat aataaagtta ttactaacaa ggaggaatat aatagatgaa gaaaagaaaa
     2761 atccaactga tactcctact tatttcggag tgggttattg ccattccatt tttaactaat
     2821 ctataagttc tttatattgc tgaaaacgca attcaaaaag ggatgttaat tgtggatttt
     2881 ctaatacctg cagagattgg ataaagcgtt caatctcttt ttgattgctt ccctttgttt
     2941 gaagaaagac actcatcttc tttaaaaatt gccacgatac tttttcaaaa acatcatacg
     3001 gtcgtaacat cctctccaac tcggcttcga agattgggat gtaggagaaa agttttcgct
     3061 ccatgagttc tgataagata tttaagagtc cttgcttcat atacaatcga ttgtgtacta
     3121 actctttaaa ttctttggat ttttcgagta aggaggttga taaaaaaaat cagatcttga
     3181 ttgctcaaga agggcatggt attgcaaaag agatagagtt caaaccaggt ccaagactcg
     3241 atagcataga gataggtggt caaaaactcg ctatcctcct ctgctagtgg gtagctttta
     3301 tttagtgaat ggatggcatc tttaatcacg atggcattca aacgacgata ggtctgcgcc
     3361 atctgttctt gatcgacttc ctccaatagc tgctctaaag cagctatatc ctgatgggca
     3421 aagcgattca caacctttcg accgattcgc atatgtggag attcttgata gttgatgagc
     3481 ttgtgcccaa actcatcaat ggtcacattt ataccttgga tagctagaat caacttatcc
     3541 gcagacagca tagactgccc tagttcaaac ttggacaact gagaagctgt tagaccctca
     3601 caagccacat ctgtctgctt aagctttctc gccaaacgta attccttgta aaattccccc
     3661 agttccattt tttcaatcat cctaccacct cctagctttt gcatattata tcattatttg
     3721 tgttcatttg tcaaaacatt ctgacacttt ggtgattgaa aaagccagcc ttaagctgac
     3781 tctaaaagga ccgagccttg tacaatacag aactcaatcc tcgttctaaa tagaatgtct
     3841 aacttttttg ggcagtacac gagcttgggg aacagccact ggaacgatga ggtgtgagct
     3901 caaaatatcc tccagttatg tttttcctaa tagtataccg gaagagtgaa aggattttat
     3961 aatggagcgg ttacaaagaa cctactttct attaaacagt atactatgaa aatgtgaaaa
     4021 tttaacattt ttttgtacaa attttataaa ttattgcctt tttaatatca atagttaatc
     4081 tcttatccag atcccccttg tgtaaacttt atctttataa gcttcaaggc ccctatccca
     4141 tctatttgca acaattagat cactttgttt tgtaaatagt tcaaaattct tttcaaaaat
     4201 tacgttatct atactaacgt ttaaatttgg ttcatatact aaaattttta taccgacaat
     4261 caatagttca ttaattatac ttaaaatagc tgactctttg taattatctg aattatattt
     4321 catccccaat ttatatattc ctactatctt tggctttcgt tccaatattt gtttaactat
     4381 gaactgtttt ctatttgtgt ttgaaatatc aatcgcttct atcactgggg catttatttc
     4441 tataaattct ttttttaatt gtttagtatc tttgggaaga caatatcctc caaatccaaa
     4501 agaaggatta ttataaaaat ttccaattct tggatctaaa caaacacctt ttattacaac
     4561 ttcagcattt aaacttctcc tctcagcaaa agaatctagt tcattaaaaa aagcaacacg
     4621 gagagctaag aatgtgttag aaaaaagctt aattgcttct gcttcagtag gagaaactaa
     4681 cataacattt ttaatattgg cagtactatg agtactaatc gaaaggaaca actctgcaat
     4741 ttttcttcct tcaactgtct catctccaac aactatgcga cttggatata aattatcata
     4801 tatagaacaa ccttctctca aaaattcagg gacaaaaatg atattttttg tatcaaacag
     4861 cctttttaat ttgtttgaaa agccgatcgg aactgttgac tttaaaataa tctttccatt
     4921 aggttttacc ctcagaatct tcgataccgt ttgttcgatt tcatatgtat taaaactacc
     4981 aattttctca tcataatctg tcggaagcgc aataatataa taatcaatat tatttttaat
     5041 ttcagaaaat gtatcaaaaa aagtaatatt taagttattc tcgcaaaaaa acttcataag
     5101 ctcttcattt ttagatggaa gaatgccctt ttttaaatta tttattttta cagaatctat
     5161 atcatatgca acaactttat atttagatgc aaatagtaac gcgtaggcca gcccaacatg
     5221 ccccaaacca attactgcta tattcataaa actacttcct tatttcttaa tccaaaatct
     5281 aatagaataa gctgccccat tccttaaata caactcttta atattgttta aaagtttttc
     5341 aactgatttc cagattatca aaatctgaga tttatagcac aatattgatg atattctatc
     5401 aatataattt tttcatcaag ttcctcttga tacattttta attctttagt ttttcccata
     5461 taactaacca tactactatc acttacatat gggaagtcct cataatatat tactttataa
     5521 cgcataaatt caagcaccct tccaatacta ttcacaaaaa catgatcaac atggtcacca
     5581 agtgaaagcg gacaatatac gacacatttg tcgtctaaat gcattaacag ctcttttatg
     5641 atatcattct ttaatgtgtc ctcatttttt aattcactat agatatgacg gtatagaaaa
     5701 ttgccatttc tatctttcct atagagacat tcatagtacg ataagtgtct aaaatcacat
     5761 tgtagacgtt cacaagctaa cctgtcttct ttcttccttt cttcaatcgg atatttccca
     5821 aggttacaca acttatgaaa ttgcttagca gagggctgta gctgttggct caaagggtaa
     5881 ccagaaaata tagtaataac aagtacaatt tctccttctg aagttaattt tgaaatataa
     5941 tcaccacagg aaaaaattgc gtcatctaaa tgtggagata aaaagatata cttagtattg
     6001 ttactcataa ccattccctc tacaatttat ctaaaaactc actaagtgtc tgattaaatt
     6061 ccacatcatc aaaaaaattc accttattct taataatgaa tatttcgtta aataaacata
     6121 tatataaata tttcaatatc ctttcaatat catcctctaa attctcctca atattttgta
     6181 tcagcccatt tacaatctta ttaaaaaaga taagctcttt atctctaaaa ttaaatattt
     6241 tcatacaact gttgtatcga aaaa
//
LOCUS       DAVKAU010000073         6222 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVKAU010000073 DAVKAU010000000
VERSION     DAVKAU010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6222
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.073"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            166..450
                     /locus_tag="VWX48_001917"
                     /pseudo
     CDS             166..450
                     /locus_tag="VWX48_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            659..1318
                     /locus_tag="VWX48_001918"
     CDS             659..1318
                     /locus_tag="VWX48_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU9172477.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIYMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1343..2410
                     /locus_tag="VWX48_001919"
     CDS             1343..2410
                     /locus_tag="VWX48_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9172478.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            2514..3524
                     /locus_tag="VWX48_001920"
     CDS             2514..3524
                     /locus_tag="VWX48_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172479.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3536..5227
                     /locus_tag="VWX48_001921"
     CDS             3536..5227
                     /locus_tag="VWX48_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9172480.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5230..5940
                     /locus_tag="VWX48_001922"
     CDS             5230..5940
                     /locus_tag="VWX48_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU9172481.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6036..>6222
                     /locus_tag="VWX48_001923"
     CDS             6036..>6222
                     /locus_tag="VWX48_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172482.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLK"
BASE COUNT         2088 a          853 c         1179 g         2102 t
ORIGIN      
        1 tactatatta tcgcttacca atatttgctt ttatatttgc taaactttca gaaaaaaagt
       61 tggagtatat gatgctaggt gactgcgtca tgttagtaaa cgaaatggaa ataactgatc
      121 atagagtaga taacttattt gaaaaaggga aaaatgagat aaaagattca tgtagtagat
      181 ttagcaatag gacatataaa agctttagaa aaagtatctg aaaaaacaga tgtttatatc
      241 tataacctat gctcgggaga aggcactagt gtattacaac ttgtaaatac atttgaaagt
      301 gttaataaga tccctattcc ttataaaata gttccaagac gttcaggaga cgttgcaact
      361 tgttatgcaa atgcagacaa agcatataag gaattaaatt ggaggacaac aaaatcgatt
      421 gaagacatgt gtagagatac atggaattag caatcaaaaa atcccaatgg ctataattga
      481 tgatactgtc tatatgagtg ctgtattttg gaaaaattac ttaacctttt aatgaaatgc
      541 atatttaatg aaagataaat taaaaaaaat gtttgacagc gcttgacaaa ggaaacggtt
      601 tcattgtata atgtaaacat gtgacaccga tgtcaaatat aaaaaagaag gtctttatat
      661 gaaaaactta acaaaaatta agttcaaaga gaatggggaa tttaatcatt tccctgggaa
      721 tacagttgta gcaaatcttt atactaaaca agatttgatg gaagttgttg atattattca
      781 atcacgttat agagaattac catttatcga taagtttact ttaactccaa ggaattctat
      841 tcacatgact gtaattgaat tgttgtgcca tgaaaatcgt gaaacggagt tttggagcag
      901 taatcttcct ctagatacac ctttacagga aatacatgat tactttgcta aacaacttga
      961 aatttttcca ttgttggatg aagaaattta tatgcgtata actgaaatgg gaaaacaaaa
     1021 catactagtt gaacctgcag atgaagcttc tgcaaagaga ttagaagaaa ttcgtactta
     1081 tgtctcagaa aaagcaggtg tttgtttccc taatcatgat agatatcaat tccatatttc
     1141 aattgggtat cttcggattc ctctaaccga agaggaggaa gaagagttta ctaaagtcag
     1201 agcagaatta actgaaattt tattagagaa gattccaact attactgtaa accgtattga
     1261 ctatactgta tttgaagata tgagacaatt tgttccatat cacgaaaaat ttaaataaaa
     1321 taataaaaaa ggagaactta tcatgaaaaa aatgaaagtt tggtctactg tacttgcaac
     1381 gggagttgct cttactacac ttgctgcttg ctctggaggt tcaaattcta cgactgcttc
     1441 ttcatctgaa gaaaaagctg ataaaagtca agaattagtt atctattcga actcagtctc
     1501 aaatggtcgt ggtgattggt taactgctaa agcaaaagaa gctggtttta atataaaaat
     1561 ggttgatatc gctggcgctc aattagcaga ccgtgttatt gctgagaaga ataatgcagt
     1621 tgcagatatg gtatttggaa ttggtgctgt tgactcaaat aaaattagag atcaaaaatt
     1681 actagtacag tacaagccta aatggttaga taaaattgat caatctttat cagataaaga
     1741 taattattat aatcctgtga ttgttcaacc attagtttta attggggcgc ctgatgtaaa
     1801 agaaatgcct aaagattgga ctgaattagg tagtaagtat aaaggtaaat attcaattta
     1861 tggtcttcaa ggtggtacag gacgggcaat tctagcaagt atcttagttc gttaccttga
     1921 tgaaaaagga gatttaggcg tatcagaaaa aggatgggaa gttgcaaaag aatactttgc
     1981 aaatgcctat actcttcaaa aaggtgaaag ctcagttgtt aaagcgttag ataaagaaag
     2041 cccaattcaa tacggtatga tctggggttc tggagcgtta attggacaaa aagaacaaaa
     2101 tgttgaattc aaagttatga ctcctgagat tggtgtacca tttgtaactg aacaaactat
     2161 ggttttaagc actagtaaaa aacaagcgtt agctaaagaa tttattgatt ggtttggtca
     2221 atcagaaatt caagtagaat atagtaaaaa atttggatct attcctgcaa ataaagatgc
     2281 cctaaaagag ttacctgaag atacgaaaaa atttgttgat caagtgaaac cacaaaatat
     2341 tgactgggaa gctgttggaa agcatttgga tgaatgggta gaaaaagctg aattagaata
     2401 cgtaaaataa gaaataagag ttatttttta tgtccaagtc tctctattat ttctaaattt
     2461 aaggaagaaa taaagagagg cttttggctt tagtaataga gggagttagt gagatgatta
     2521 aatttgataa tattcaaatt aaatatggtg attttgttgc aattgataat ctgaatttag
     2581 atatacatga aggggaattc tttacatttc ttgggccttc aggatgtggt aaatcaacta
     2641 ctttgagagc attggtaggt tttttagatc catcatcagg aagtattgaa gttaatggaa
     2701 cagatgtcac tcatttggaa cctgaaaagc gtggaattgg tattgtattt caatcttatg
     2761 cgctatttcc aactatgact gtttttgata atattgcatt tggtttaaaa gttaagaagg
     2821 tagctccaga tgttattaaa gctaaagtat cagcagtggc agcaaaaatt aagatctctg
     2881 atcaacagtt acagcgtaat gtatcagaat tatctggggg tcaacaacaa agggtagcat
     2941 tggctcgtgc tctggttctt gaacctaaaa ttctttgtct agatgaacca ttgtcaaacc
     3001 ttgacgcaaa attacgtgta gatttgagaa aagagttgaa aagacttcaa aaagagttag
     3061 gtattactac tttatatgtt actcatgatc aagaggaagc cttgacttta tctgatagaa
     3121 ttgcagtctt taacaatgga tacatcgaac aggtcggtac accagtagag atttatcata
     3181 attctcaaac tgaatttgta tgtgatttta ttggagatat taatgttttg accgatgaaa
     3241 cagtccacga agtattattg aaaaatacaa gcgttttctt agaggataaa aaaggataca
     3301 ttcgattaga gaaagttcga ttcaatcgtg aaactgaaca agattttatt ctaaaaggga
     3361 caattattga tgttgagttt tctggagtta caattcacta tacaataaaa gtttctgaaa
     3421 gtcagattct taatgtaaca agtattgata gtcaggctgc tattagatct gtcggagaaa
     3481 gtgtggaatt atttatcaca ccatcagacg ttctgcaatt ttaaggaggt gcagtatgcg
     3541 tcataaatta aatttaaaag attggcttat tcgtttaggg ttaatctggt tcttagtaac
     3601 atttattatt tatccaaact ttgatctagt agtgaatgta tttgtaaaag gaggagaatt
     3661 ttcccttgat gctgtacatc gtgttctaaa atctcagagg gcacttcaga gtattatgaa
     3721 cagttttaag ttagcatttt cactcattat tacagttaat gtcgtaggta ttctttgtgt
     3781 tctatttaca gagtactttg atattaaagg tgctaaaatt ttaaaattag gttatatgac
     3841 ctctttaatt tatggaggag tggttttagc gactggatat aaatttgtct atggtccata
     3901 tggattgatt acaaaatttt tacaaaatgt tatcccttct ttagacccta actggtttat
     3961 tgggtatggt gcagtcttat tcattatgac attttcagga actgctaatc atacattgtt
     4021 tttaacaaat acaattcgaa gcgttgacta tcacactatt gaggctgctc gaaatatggg
     4081 agcaaaacca tttactgttt tccgaaaagt agtgttacca accttaattc caactctatt
     4141 tgcacttact attatggttt ttcttagtgg tttatctgca gtagcagcac ccatgattgt
     4201 tggtggtaaa gaatttcaaa ctataaatcc aatgattatt acatttgcag ggatggggaa
     4261 ttctcgtgat ttagctgcct tacttgcaat tattttaggt attgcaacta caattttgct
     4321 tactatcatg aataagatag aaaaaggtgg aaattatatt tctatctcta agactaaagc
     4381 gcctctaaaa aaacaaaaaa ttgcgtctaa gccttggaat atcattgctc acattgtagc
     4441 atatggattg ttcacagttt tcatgcttcc actaattttt atagtattat actcatttac
     4501 agatccagtt gcaattcaaa caggtaactt aacattatca aactttactt tagaaaatta
     4561 tcgcttattc tttagtaata gtgcggcatt ctctccattc ttggtcagct ttatttattc
     4621 tattattgct gcgacaacag caacaattct cgcagttgta tttgctcgtg ttgtcagaaa
     4681 acataaatct cgttttgatt tcttatttga atatggtgct ctacttcctt ggttactacc
     4741 aagtacactt ttagcagtaa gtttattatt tacttttaat cagccacaat ttcttgtctt
     4801 gaatcagatt ttggtaggta gtttggtaat tctacttatt gcatatatag ttgtaaaaat
     4861 cccattttct tatagaatgg tacgtgctat tttatttagt gttgatgatg agatggaaga
     4921 tgcagcaaga agtatgggtg cttcaccttt ttatactatg atgaaggtta tcattccatt
     4981 tattttaccg gttgttctct ctgttattgc tttaaacttt aactctttat taactgactt
     5041 cgacttatct gtattccttt accatcccct agctcaacca ttaggtatta cgattcgatc
     5101 tgcaggtgat gaaacagcaa catctaatgc acaagctctg gtatttgttt atacaattgt
     5161 tctgatgatt atttctggaa cggtattata cttcacacaa agaccggggc gtaaagtaag
     5221 gaaataatca tgacagccac tagtcttggg ttatcaaata ttgaaatagt tgtcaggatt
     5281 gttttatcag tagtcattgg tagtataatt ggtttagaga gagggagcaa atcccagcct
     5341 gcaggcatcc gaacttatag tattgtttgt ctagctgcat gtttgattat gatgacgaat
     5401 gaatacgtat cttataaatt tgggacagga gatcctacac gattaggagc tcaagttata
     5461 tcaggtgtgg gttttctagg cgctggaacg attcttatta cagataaaaa gaaaattaca
     5521 ggtctgacaa ctgcagcagg catttgggct tcggcaggaa ttggattagc tattggagta
     5581 ggtttttatg agggagctct tttagtagcc atttctgttt ggggtgtgat atccatgttc
     5641 caaccactaa aaaaatatct gcaaaatcgt tctaaaatga ttgaattgta tatagtggtt
     5701 aaatctacag aagcctataa tcgtgtattg gtttattgtg cagaaaatgg tatcagaatg
     5761 accgattcaa gaacagcgtt tggagatgtt aattctgaca gaattgaata ctttgatgtt
     5821 ccggacaaaa aaatagcgtc atttattact ctggaattat caggtagatt tgaacatctt
     5881 cgactgatgg aagaaattgc taatattgta ggtgttattt atgtcgaaga aattagctga
     5941 aatttagtaa acaaagggac agatgttttt gtccttttgc tttttagatg ttttaatcat
     6001 ctaatttttg agtagatttt tgctcagagg tttttatgaa agattataaa atcaattttg
     6061 atttaggtaa aatagaatat tttgataata attgtttgat acaagtatac aaatttattt
     6121 ctttttatga tatttgtgaa atggtgtttg cctttcattt acctcctgat gagttgataa
     6181 caaatgttat ctttaaagaa aaaattaact ctatgttaaa at
//
LOCUS       DAVKAU010000074         6090 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVKAU010000074 DAVKAU010000000
VERSION     DAVKAU010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6090
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.074"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..120
                     /gene="deoA"
                     /locus_tag="VWX48_001924"
     CDS             <1..120
                     /gene="deoA"
                     /locus_tag="VWX48_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Catalyzes the reversible phosphorolysis of
                     thymidine, deoxyuridine and their analogues to their
                     respective bases and 2-deoxyribose 1-phosphate; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU9172483.1"
                     /translation="VAKVYTNEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            138..800
                     /gene="deoC"
                     /locus_tag="VWX48_001925"
     CDS             138..800
                     /gene="deoC"
                     /locus_tag="VWX48_001925"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU9172484.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            787..1176
                     /locus_tag="VWX48_001926"
     CDS             787..1176
                     /locus_tag="VWX48_001926"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9172485.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            1267..2319
                     /locus_tag="VWX48_001927"
     CDS             1267..2319
                     /locus_tag="VWX48_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU9172486.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            2463..3998
                     /locus_tag="VWX48_001928"
     CDS             2463..3998
                     /locus_tag="VWX48_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172487.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            3991..5049
                     /locus_tag="VWX48_001929"
     CDS             3991..5049
                     /locus_tag="VWX48_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9172488.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            5052..6008
                     /locus_tag="VWX48_001930"
     CDS             5052..6008
                     /locus_tag="VWX48_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9172489.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         1716 a         1131 c         1424 g         1819 t
ORIGIN      
        1 gttgcaaaag tatacacaaa tgaaaaaatt ccacctcaac tagttacaga tttccaaaaa
       61 tgtgttaaaa taagtgatga agtgaaaaaa atccgtgaaa ttgtagaaat catctcctaa
      121 atggagggaa aaccgaaatg aaattaaata aatatataga tcatacgctt ttaaaacaag
      181 atgcaaagaa aaaacaaatt gatagtttgt tgtctgaggc tagagagtat gactttgcca
      241 gtgtttgcgt taatccgacc tgggttgaac atgctaaaaa aggacttgaa ggcacagatg
      301 ttaaggtttg cacagtagta ggtttccctt tgggagcaac aacttcagcc gtgaaagcat
      361 ttgagacaaa agaagctatc caaaatggtg cagatgagat tgatatggtg atcaatgttg
      421 gagctctcaa atcaggtaat ttagccttgg ttgagtcaga tattcgcgca gtagtggaag
      481 caagtggtga taagttagtg aaagtcatta ttgaagcttg ccttctgaca gaccaagaaa
      541 aaattgttgt ttgccaattg gcccaaaaag ctggggctga ctttgttaaa acatctactg
      601 gtttttcaac tggtggtgct acgatagcag atgttacatt aatgcgtgaa acagttggat
      661 ctgatatggg agtcaaggct gctggtggag ctcgttctta tgcagatgct cttgcctttg
      721 tcgaagcagg tgcgacccgt atcggaacgt cagctggggt agctatttta aaaggagaat
      781 tggcagatgg cgactactga gttgattgaa ctggcaattg aaaccagcaa acatgcctat
      841 gtcccctatt ctcactttcc tatcggagca gttttagtag ccaaagacgg aaatgtttac
      901 acgggagtga atatcgaaaa tgctagctat cctttgacca attgcggtga gagaacagct
      961 atttttaagg ctatatctga aggccaaaga gaattttcag aattgattgt ctatggtcaa
     1021 actgaaaaac cgatttcacc atgtggtgct tgtcgccaag taatggtcga attttttgaa
     1081 caagatttaa aagtgacctt agtcgcaaaa gataaatcga cggtcgagat gacggtcggg
     1141 gagttacttc catattcttt tacagactta aattagtctg agtcgctctt tgagtggcaa
     1201 gggtctttgt gaccaatcaa tccatacttg caacatcgtt gcacatctta tttaggaggt
     1261 tcagtaatga acaagaaaca atggctaggt cttggcctag ttgcagtggc agcagttgga
     1321 cttgctgcat gtggtaaccg ctcttctcgt aacgcagctt catcttctga tgtgaagaca
     1381 aaagcagcaa tcgtcactga tactggtggt gttgatgaca aatcattcaa ccaatcagct
     1441 tgggaaggtt tgcaggcttg gggtaaagaa cacaatcttt caaaagataa cggtttcact
     1501 tacttccaat caacaagtga agctgactac gctaacaact tgcaacaagc ggctggaagt
     1561 tacaacctaa tctttggtgt tggttttgcc cttcacaatg cagttgaaga agcagctaaa
     1621 gaacacactg acttgaacta tgtcttgatt gatgatgtga ttaaagacca aaagaatgtt
     1681 gcgagcgtaa ctttcgctga taatgagtca ggttaccttg caggtgtggc tgcagcaaaa
     1741 acaactaaga caaaacaagt tggttttgta ggtggtatcg aatctgaagt tatctctcgt
     1801 tttgaagcag gattcaaggc tggtgttgcg tcagtagacc catctatcaa agtccaagtt
     1861 gactacgctg gttcatttgg tgatgcggct aaaggtaaaa caattgcagc cgcacaatac
     1921 gcagccggtg cagatattgt ttaccaagta gctggtggta caggtgcagg tgtctttgca
     1981 gaggcaaaat ctctcaacga aagccgtcct gaaaatgaaa aagtttgggt tatcggtgtt
     2041 gaccgtgacc aagaagcaga aggtaaatac acttctaaag atggcaaaga atcaaacttt
     2101 gttcttgtat ctactttgaa acaagttggt acaactgtaa aagatatttc taacaaggca
     2161 gaaaaaggag aattccctgg cggtcaagtg atcgtttact cattgaagga taaaggggtt
     2221 gacttggcag taacaaacct ttcagaagaa ggtaaaaaag ctgtcgaaga tgcaaaagct
     2281 aaaatccttg atggaagcgt aaaagttcct gaaaaataat ggatggaagt catttcttag
     2341 gaagcggcca agggccgctt ttttaagagt tgagacaaag tcattttgtc tcagtaaagc
     2401 ttgctactag acaaactagc aagttttatt gaaataaaat aagactctga aaggaagagc
     2461 acatggcaca cgaaaatgtc attgagatgc gtgatattac caaggtgttt ggtggatttg
     2521 ttgctaacga caaaatcaac ttgcacctac gaaaaggtga aattcatgca cttttaggag
     2581 aaaatggggc tggtaagtcc acgctaatga acatgttagc agggcttctt gaaccaacta
     2641 gtggtgaaat cgcggtcaac ggtcaagttg tcaatctcga ctccccatct aaagcagcta
     2701 gcttgggaat cgggatggtt caccagcact ttatgttggt tgaagccttc acagtggctg
     2761 aaaacatcat tttaggtagt gaattgacta aaaatggtgt gctagatatc gctggagcta
     2821 gcaaagaaat caaggctctt tctgaacgtt atggcttagc tgttgaccct tctgccaagg
     2881 tagcagatat ctcagttgga gcccaacaac gtgtagaaat tttaaaaaca ctttatcggg
     2941 gggctgatat ccttatcttt gacgaaccaa cggctgtttt gactccatca gaaattgatg
     3001 agttgatggc tattatgaaa aatcttgtca aagaaggaaa atcaattatc ttgattaccc
     3061 acaaattgga tgaaattcga gcagtttctg accgtgttac agttatccgt cgtgggaaat
     3121 caattgaaac cgttgaaatt gcaggggcta ccaatgctga tttggcggaa atgatggtag
     3181 gacgttctgt ttcctttaaa acagagaagc aagcctctaa accaaaagaa gtggttttgt
     3241 ctatcaaaga tttggtggtc aatgaaaacc gtggtgttcc agctgttaaa aatctgtcct
     3301 tggatgttcg tgctggagag attgttggta ttgcggggat tgatggaaat ggtcagtctg
     3361 aactgattca agccattaca ggtcttcgta aggttgaatc tggtagcatt gagctaaaag
     3421 gagattcaat tgtaggcttg cacccacgtc agattacaga actaagtgtt gggcacgttc
     3481 cagaagaccg tcaccgtgat ggcttgattt tggaaatgat gatatctgaa aatattgccc
     3541 ttcaaaccta ctataaagaa ccacatagta aaaatggaat tttgaattat tcaaatatta
     3601 cttcttatgc taaaaagctg atggaagagt ttgatgttcg cgctgccagt gaattagttc
     3661 ctgcagctgc actctcagga ggaaatcaac aaaaagcaat tattgctcgt gaaattgatc
     3721 gagatcctga tctccttatc gttagccagc caactcgtgg gttggatgtc ggtgccattg
     3781 agtatatcca caaacgcttg attgaagagc gtgataatgg caaggctgtc cttgttgtca
     3841 gctttgaatt ggatgagatt ttaaacgtct cagaccgtat tgccgttatc cacgatggta
     3901 agattcaagg tattgtatca ccagaaacaa ccaataaaca agaacttggt gtcttgatgg
     3961 ctggtggaaa cttgggaaag gagaagagtg atgtctaaaa aattacaaca aatttcggtt
     4021 cccttgattt ctgtatttct aggaatttta ctcggagcca ttgtcatgtg gatcttcggt
     4081 tatgatgcta tttggggcta cgaagaattg ttctatacag cctttggcag tctgcgtggg
     4141 attggagaaa tcttccgtgc tatgggtcct ctggtcttga ttggtcttgg ttttgcggtt
     4201 gccagtcgag ctggtttctt taacgtcgga cttcctggtc aggctttggc aggttggatt
     4261 ctcagtggtt ggtttgcgct gtcgcatcca gatatgcccc gtcccttgat gattctagca
     4321 accatcgtga ttgccttgat tgctggtggg attgtcggag cgattccagg tattcttagg
     4381 gcctatctag ggacgtcaga ggttattgta accatcatga tgaactacat tgtcttgtat
     4441 gtagggaatg cctttatcca tgctttccct aaagacttca tgcaaagtac agattcgacc
     4501 attcgtgttg gggctaatgc aacctatcag acaccttggt tggctgagtt gactggtaac
     4561 tcacggatga atattggtat tttctttgcc atcattgccg ttgcagttat ttggttcatg
     4621 ctcaagaaaa caactcttgg ttttgaaatc cgtgcagttg gtcttaatcc acatgcttca
     4681 gaatatgctg gtatttctgc caagcggact attatcctat ctatgattat ttcaggtgcc
     4741 ttggcaggtc ttggtggagc tgttgaaggt ttgggaacct tccagaacgt ctatgttcaa
     4801 ggttcgtcat tagctatcgg atttaacgga atggcggtta gtttgcttgc ggccaactca
     4861 ccaattggta tactctttgc agccttccta tttggcgttc tccaagttgg ggctcctggt
     4921 atgaatgcgg cgcaggtacc atctgagctt gtcagcattg taacagcgtc tattatcttc
     4981 tttgtcagtg ttcattacct tatcgaacgc tttgtcaaac cgaaaaaaca agttaaagga
     5041 ggtaagtaaa gatgtctatt ataaccttgc tccccctctt ggtgtcttct atgctgattt
     5101 actcagcacc tctcatcttt acaagtatcg gtggtgtttt ctctgaacgt ggtggtgtgg
     5161 taaacgttgg ccttgaagga attatggtta tgggtgcctt ttctggagtt gtctttaacc
     5221 ttgaatttgc agaacaattt ggagcagcaa ctccatggct atccttgctt gtagcaggat
     5281 tggttggtag tgttttctct atcatccacg cagcagcgac ggttcatttc cgtgcagacc
     5341 atgttgtcag cggtacggta ttgaacttga tggcgcctgc cttggctgtt ttcttagtta
     5401 aagttcttta taacaaagga caaaccgaca acctaagtca aacttttgga cgctttgatt
     5461 tcccagtctt ggcaaatatc ccagtgattg gtgatatctt cttcaagtca actagtctac
     5521 ttggttatct ggcgattgcc ttctcattcc ttgcttggtt tattctcttt aagactcaat
     5581 ttggtcttcg tctccgctct gtcggtgaac atcctcaagc agcggatacc ttgggaatca
     5641 acgtctacaa gatgagatat ttagggatta ttatttcagg ttttctaggt ggaattggcg
     5701 gagcgattta tgcgcaatca atctcagtta acttttcagt gacaactatt gttggacctg
     5761 gatttatcgc ccttgctgcg atgatctttg ggaaatggaa tccaatcggt gctatgcttt
     5821 ctagtctctt ctttggactt tcacaaagtt tggctgttat cggttctcaa ttgccgttcc
     5881 tacaaggagt gccagcggtt tatcttcaaa ttgcacctta tgttttgaca attcttgtct
     5941 tagcagcctt ctttggaaaa gcagtcgcac caaaagcaga tggtatcaac tacatcaaat
     6001 caaaataagc atacaaaaaa acgtcagtcc aatgactgaa ctgcccccca aaagttagac
     6061 agaaaaaatc taacttttgg ggtgttttta
//
LOCUS       DAVKAU010000075         6069 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVKAU010000075 DAVKAU010000000
VERSION     DAVKAU010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6069
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.075"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..197
                     /locus_tag="VWX48_001931"
     CDS             <1..197
                     /locus_tag="VWX48_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172490.1"
                     /translation="SVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYYFLPIEI
                     LIAISGANLLLSFLKKLQTK"
     gene            1079..2137
                     /locus_tag="VWX48_001932"
     CDS             1079..2137
                     /locus_tag="VWX48_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172491.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLIQNQSKVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2452..3429
                     /locus_tag="VWX48_001933"
     CDS             2452..3429
                     /locus_tag="VWX48_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172492.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIVCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            3806..4180
                     /locus_tag="VWX48_001934"
     CDS             3806..4180
                     /locus_tag="VWX48_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU9172493.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            4388..5290
                     /locus_tag="VWX48_001935"
     CDS             4388..5290
                     /locus_tag="VWX48_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172494.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLITIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIRWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEAILGKI
                     VDSESTLLCIGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            5346..5699
                     /locus_tag="VWX48_001936"
     CDS             5346..5699
                     /locus_tag="VWX48_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU9172495.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGTYLSKRACQGICVALAMSPGT
                     FIALTGAAVLTKKLINYIKVGSFGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            5696..>6069
                     /locus_tag="VWX48_001937"
     CDS             5696..>6069
                     /locus_tag="VWX48_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172496.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKV"
BASE COUNT         2012 a          769 c         1069 g         2219 t
ORIGIN      
        1 tttcagttat tgttgcattc ctgtatcata aaattacaga gtatgtcaac aacaggaaaa
       61 ttgatattgt tatttttcta tcattgctga tttctcattt tatttggaat tactattttt
      121 taccaattga aatattgata gcaatcagtg gagcaaattt actattaagt tttttaaaaa
      181 aattacagac taaataatat taatctgtgt aatacagtag ctcggtcatt agattctatt
      241 gaagatataa attaaaaatg aggctgggaa aaaactcaat ttgaaaatga gattgagtaa
      301 atctttctat ctatataacg tatatcatca atatttttga acacctgata atatgcattt
      361 ttcttatttt aaagattttt tgcctttctt catttcttga atgaattgga gagatgactt
      421 tatttaggtg tttgacatta ctatagatag gatttagcag tactaatatg aactcatatt
      481 ataggtgcag acttaaattt tggaagcaag ctaaaggata tcttatctag gtaactaagt
      541 gctataacaa gatatattgg tggagttagt atggcaacta ttactaatgc tcttaatatt
      601 gcggctactg ttgctgaagt cttctcatta ggaggagcca ttgcatatgg tttagatatc
      661 gtagacggta aatttgatgg gtatttatgg gcgtaaaact atagctatga aacatttttt
      721 tgcaggaatt ggtgaaattc attttttgtt atttttatta tatctaagca tgtctgctag
      781 tccaattatt ggactagtga ttggatatac taaaataaat ctaataaatt ctattattat
      841 agctcttggt atgatattgg cattaatttt ggtattatca agagtgtata gaaaatattt
      901 ttatagagac gatgatgact aaagttttta tcaataattt gggctccttg tcaactgtag
      961 tgggttgaag aaaagctaac gtctggggaa ggggttaaag ctttgcttta tcaaatattg
     1021 acttacagag ttgctctatt gtattgatgt attcttagta aataatatgg tgttttgaat
     1081 gaaagatgat cagaaatatt tattagcggg actttattcg cttctagttg caatatttta
     1141 ttttccattg attgagtcca aggggatttt tgtaagtata ttgatggcgg ttttactttt
     1201 atatttaata tacttcattg caacagtcat tcatattgtg ataattaagt ttataagaaa
     1261 aaaatctttt aagtatttgg ttctatatcc atttacttat gatgggagct ggagatttca
     1321 acctataaac ttactctact ttccagaaat ggtgagagat gtcattccga ttaatttagt
     1381 tcaagaatat tgccaaggac aaccttacgg actgttaaaa aagatgctga aaagaattcg
     1441 attgtcacga gagatatctt tactcctggc tactattatc gtctattttt ttacgcatag
     1501 aattctacct ctttcagtat ttacgttcat attttcttac atattgctat ttgcacaatc
     1561 ttatttgggt ggtaataccg tttggattgg aaatagaaga ttaataatag atgatgaatt
     1621 tgaaaaaatc ttgctttcaa aaagttatat aaaagaaata tcatctgcac gatactcaga
     1681 atacttgaca tgtgaataca aaaactttac accaatcata ttgttagcta tttttgaaaa
     1741 tttgcttgac tcctacttga ttcagaatca gagtaaggtt gacttagata ttttttataa
     1801 agttttacct ttgctttata aagaaaaata tactatggga ttcaattact ttgtaagttt
     1861 aaattattta ctatataagg ttggattttt gggaatcatt tacgataatg aagcattaag
     1921 agatttgtca aaacaatatt taaacaaaaa tatttcggaa ttacaagatg gttctttcga
     1981 gggcggtata caagatgctg ttgcctctaa acaaatagta gttataaatg aatttatagc
     2041 ttgtttaaat tccagatgcg tgccatccca atatgataga tttttttata aagatagacc
     2101 ttatattttt tccagaaaga gtcctattaa ggggtgaaaa tttgttacat ttggattaac
     2161 aagtgtccta gggattagaa ataactctag tatagctaga tatttttgag taactagaaa
     2221 tatcattagg ctacccatat gattgccaga aaagatggct gatgaatctt atttatactg
     2281 ttgcagtagg cattgtctag gataaataag ctatcttgat gggggagatt ggaataattt
     2341 tagtagaaac attaaaggat tatggacaag tagcgtagga ttaggtgatg caatgtgcta
     2401 agttggcttg gtgttagcag tagtattatt taacaatgga aagtagacta aatgaaaaat
     2461 aagcgttatt tttttgacac aattttaata attttactgc ttataagcac gatattttgt
     2521 gtcagcccag tatttataaa attggacatc ttaggaactc cctctcatgc catcttaacc
     2581 tttgtattgg cgataccgtt attctatatt ttgtctcaat gcttacatac tttgctatta
     2641 ctagtttcct caatcgtttg taaattaaga ccaatttatt tttattttat atttgtgatc
     2701 attataggag ctaggaaata ctatcgaatt ctctttcacc aactaatggg atttagtcca
     2761 ggaatagcag tgttttataa ggagagtcaa acaactaaga atctgtttaa attttactac
     2821 ttcttgtact ttacaacact aatttcatac tattttttct ttacttttgt gtatgacaaa
     2881 tcgttgcttt tgcctcttat tccattttct attatcatag cattagtaca aaaactttat
     2941 agaattgaga atcaacaatt atttctgtta aaatcaaagg tactaacaat actggaatct
     3001 aagagggatt gtgagtttaa tcttcaggat tatcatgaaa tttggaaatt gcaatcaaaa
     3061 tctgagttgc catgcgtggc tttatcttat atcagtttga tcaagccata tctttcagag
     3121 agcgtgcgtg aacaaattga tttattagaa gttaagcgat ttaaaaaaat aaatcatcca
     3181 atatcacttt atggtatgtt ggatgttata aaattaaatc tatatttacg gcattataat
     3241 gaaaaaaata aatatgaatc aatgttaaag aaaattttag aggtaagacc agactttgtt
     3301 ttaatcgagc agaatattga tgatagttta aatagctcgc aaccattatc tttatcttta
     3361 gctatttcag aaatccaact tttgcttgaa gtgtatatag ggatcaaaca tgtttcaatt
     3421 aggagataaa actagaataa catttgctat tataggggca agttgcatat tagtcagtat
     3481 gtatcttata cctctcatta acacggataa taaattttgg gaaatacttt tatttatatt
     3541 aggtgtattg ctaattggaa ttgcgttact aagtcaaaaa aaataaattt tgaaatagta
     3601 ttagtgagtt cgcaatcatt tattgctagt ggcttagaac tgttaagttt caaacaataa
     3661 ttgattttaa accttaggta acctataaaa acaaataagg tagagaaagg atatcttatc
     3721 taggtagcta agtgataaaa acacagtcgt ctatcacttg ttaggaaact atcctaacta
     3781 tgcttaataa aaaaggagaa aataaatgga actcgtatta ccaaataatt atgttgttct
     3841 tgagcaagaa gagatgatgt atcttgatgg gggattttct attccgagat ggcctgttgc
     3901 aacagccatt aatatagctt ttaatggtgt tttaggtgga ggagcaatca gtctagttag
     3961 aaattatatt cgtaattatg gtttgcggcg agttacaagc gcaattgctg gagcagctgc
     4021 aagatatgtt ggggtacgag ttgcaaatag agtggcagga tttgcactgt ctgctattaa
     4081 tggatttgca gcttggatgt caattggcga tgctattaca acaatctggg ccaataatga
     4141 tgtaaatagg agagacccaa atttaaacgc cttgtggtaa ctagatatgg gtattaaaat
     4201 ggaaaaaatt tttgttatta ttttttttgt atgtctattt atatcatcca taactttttt
     4261 agcctatgat tttgttagcg aagaaataaa aaagttgatt atttggatga atgtcgtttt
     4321 tttgatttta atcatagcaa tgatgattta tccaaaatta agaaaatgat aaggacactg
     4381 taaaattatg atacgtaaac taattgtttt cttactaatg ctccctcttt ttgtcttgtg
     4441 gctagagttg catgtcctag tgaataactt actattgaat ctagaatctc cccttgattt
     4501 tgtgattagt atgagtcttg ctttttgtag tttgatttta tcaaaaatag ttttagacat
     4561 actatacgca ttgaaagatt tatacaagaa agaaggtctt attacgattt ttccctttat
     4621 ttttataaga aggaaaaaag tgaatgtgag attctcgccc tatttttcat tccatcgtaa
     4681 aagtttgtcg cctgatgatt taagatctag gattagatgg agttttattc ttgaaattgc
     4741 tattatccta gtatttattt taaaaattcc ttttgcaatc atcatgctta ctacaatatt
     4801 tttctggact ataatggata tcaatcatct cgtttttaat aagacggaat ttctttttaa
     4861 tcaaaacaaa tggcaaaaag aagattcgtt tgaaagtgat ttgacgaaaa cgttaaagga
     4921 taaaatacaa aagtcagagc taagttattc tgacttaatg tctctacagc tgtatgatgc
     4981 gatgaaccaa tccacctttt taacggatag tgaactcttt gaggctattc tgggaaaaat
     5041 tgtagattct gagagcactc ttctttgtat aggacttgta gagttgctgc tatatgaaat
     5101 gtctattagt aacaataaca actggtccaa caaggttgat aaaattagga tacacctcat
     5161 cagaatcaat caattagatt ttttctatta tacaagttgg ttaaggcaaa attttgattt
     5221 ctgtatgaat agagagtatc ataaaatgaa atctcggaaa ttattactga gtaataaaaa
     5281 gatagtttaa gttcgtccta tttgtaaaac aaatgaaaca atttcaacta aggaggagaa
     5341 aacaaatgga acttgtatta ccaaataatt atgttgtgat tgatgaagaa gaaatgatgt
     5401 atcttgatgg gggaacttat ttaagcaagc gtgcttgtca aggaatttgc gtagctttag
     5461 ctatgagtcc aggaactttt atagcattga ctggagctgc agttttaacc aaaaaactaa
     5521 taaactatat taaggttgga agctttggag gctggcttat tggtgcagca gcaggtgtat
     5581 tggctacagc agcaggaaaa atagcttact gtattggata tggtgttctt aatagaggtt
     5641 gtgatattaa cgggaaccct tatccttggg atggattcat atctgcaaca gtaagatgag
     5701 taatgtagat aagattcgaa aaatacacat catcgtgtgt tgggtgtata tatttttatc
     5761 attcagggcg attataaatg atacggagta ttttttgctt atttttttag cttttatcta
     5821 ctcaatagta tcactacctc tatattctgt gaaaaataaa atagtatcta tctgtctagc
     5881 cataaattcg attctgttaa tgagtttccc cattttaatc aataagtttt tcccagaaag
     5941 ttttttgact tataccgtat taataagtgt ttttattaca gagttgataa tttttcattt
     6001 aattgggaaa gattttgata ttaaattgac taacgaatat aagaaaatta gtcagtttag
     6061 aagcaaggt
//
LOCUS       DAVKAU010000076         5520 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVKAU010000076 DAVKAU010000000
VERSION     DAVKAU010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.076"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            432..1142
                     /gene="deoD"
                     /locus_tag="VWX48_001938"
     CDS             432..1142
                     /gene="deoD"
                     /locus_tag="VWX48_001938"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9172497.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1165..1689)
                     /locus_tag="VWX48_001939"
     CDS             complement(1165..1689)
                     /locus_tag="VWX48_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU9172498.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1742..1978)
                     /locus_tag="VWX48_001940"
     CDS             complement(1742..1978)
                     /locus_tag="VWX48_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU9172499.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(2046..2966)
                     /locus_tag="VWX48_001941"
     CDS             complement(2046..2966)
                     /locus_tag="VWX48_001941"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU9172500.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3156..3560
                     /locus_tag="VWX48_001942"
     CDS             3156..3560
                     /locus_tag="VWX48_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172501.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFICSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            3776..4357
                     /locus_tag="VWX48_001943"
     CDS             3776..4357
                     /locus_tag="VWX48_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9172502.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4354..>5520
                     /locus_tag="VWX48_001944"
     CDS             4354..>5520
                     /locus_tag="VWX48_001944"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU9172503.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAK"
BASE COUNT         1592 a          932 c         1231 g         1765 t
ORIGIN      
        1 ggtttgaaga gattttagaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaagcaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa aggaattgac cccaccctaa
      181 aagtagtggg aaaaagatag ttggtctagc gagcatcgct cactgcgccc aactcctatt
      241 ttcccttcgc tttttgatgg gtttggtatc tttctcaata taaaatataa aataaagaaa
      301 gatagagcgt gtgttttgat ttgaacacga gcggaaaact cggaaaatag ataatctgac
      361 tgaaaaatca ggatttctcg tcaggttcct aattttcagt cgttttcttc tcgctctttg
      421 tatcataaat tatgtctatc catattgctg ctcagcaggg tgaaattgct gataaaattc
      481 ttcttcctgg ggatcctctt cgtgctaagt ttattgcgga gaatttcctt gatgatgctg
      541 tttgttttaa cgaagtgcgt aacatgtttg gttacactgg tacttacaag ggtcactgtg
      601 tatctgtcat gggaactggg atgggaatgc catctatttc gatttatgcg cgtgagttaa
      661 tcgtagacta cggtgtgaag aaattgattc gtgtgggaac tgcaggttct ttgaatgaag
      721 aggttcatgt tcgtgaatta gttttggcgc aggcggctgc aaccaactca aacatcgttc
      781 gtaatgactg gccacagtac gattttccac aaattgctag ctttgatttg cttgataaag
      841 cttaccatat cgccaaaaaa cttggtatga ctactcacgt tgggaacgtt ttgtcatctg
      901 atgtctttta ctcaaattac tttgaaaaga atatcgagct tggtaaatgg ggagtcaagg
      961 ctgtggaaat ggaagcagca gctctttact atcttgctgc ccaataccat gttgatgcgc
     1021 tagctatcat gaccatctct gatagcttgg tcaatccaga cgaagacaca actgcagaag
     1081 aacgtcaaaa taccttcact gatatgatga aggttggttt ggaaaccttg attgcagaat
     1141 aattatagcc aaaaaggaag ccctttatga attgtaggac ttccttttct tatccagaaa
     1201 ttgatctagc tctctctgat ttcgaagaat agtgacttta tgtgaatatt cttggcaaag
     1261 tttttggtaa ttttcttttt gagttttgct acgcccatcc caaagaatcc atctgataaa
     1321 ctcccactca aagcgttcag ggcaatctgc cgccatactt tctctgactt ttccacggta
     1381 tttaagataa cgcttaaagg ctctaaagag acaggtcaat ggcgaaaaat tgagaaagat
     1441 gatttggtca gcttcttgca ttcgttcttg gtagtagcac caagaataat taccatcgat
     1501 gacccaagct ttatgcttgg tgagaaagtt ttttatctcg gttaacatcc attcgcagtc
     1561 actgtcttgc caaccaggtt gaaattggag tgtgtccatg tgcagttttg gaatggagta
     1621 gtagttagat aacttttctg ctagagttga cttaccagaa ccagaatatc cgataattgc
     1681 gattttcatt ttctaccttt tcctatttgg agacaaaaaa acagcctcta tggactgttt
     1741 cttatttagc aagtttagct gaaagacgag ctttatcgcg gcttgctttg tttttgtgaa
     1801 tcaaaccttt agtttctgct ttatcgatag ctgagctagc agcacggaaa agttcttcag
     1861 atgggtttgc ttcgaaagct tttatagcag tacgcatagc tgatttttga gctgagttct
     1921 tttcgttttg tttaacgttc aattcagcgc gtttgatagc tgatttaatg tttgccaatg
     1981 ttcttacctc catatttact aactatacca ttatatatga aaacttacgt tttgacaagg
     2041 gaaaattact tttttaagta aatttcatcg atttcatggt tcttgctttt atgaagaatc
     2101 acttctgcac gatttctggt tggttcaata taattttgca gatttgtgag attgatactg
     2161 gtccagacct gatgggcaaa ggactccact tccccaatcg gcatctgagt aaaacgataa
     2221 tagtagctat cagggtcgtt ttgggctagg ctcagcattt tcaagaaacg gtccagatac
     2281 caactttcaa tatcatccac tccagcatct acatagatgg aaaagtcaaa gaagtcagtg
     2341 atatagagac gatcgttttg tggattttga aagacattaa ttccctcaac aattacaaaa
     2401 tcagcagctt tgacactttg tttcttttcg ggtacgatgt cgtaaacttc atgagaatag
     2461 acaggaatat ctacatcttg tccatttttg atgcggtcca agaagttgag aagagcttcc
     2521 atatcatagc tttcaggaaa tcctttacga tttaaaatcc cctgctcaat caaggtttga
     2581 ttgggataga gaaaaccatc agttgtaacc aactcaaccg tagcatctgt aaacgtacgg
     2641 gacagtagga tttgaagtag gcgactggtt gtggattttc caacggcaac actcccagaa
     2701 accccaataa taaaaggttg agatttactt tcacgttgga ggaaaattcc ttttgaaaag
     2761 gctaaatctt ccttagttcg cttgtaaatc tgaatcagat gagccaaggg gagatagata
     2821 tctgtaacgt cttggagact gatttggtca ttaaaactct tgatagattc caattcttct
     2881 tctgtcaaag gaggtgttgt ctttcgatgt aaagattgcc aagtctggcg gctgattttt
     2941 tcaaaatgta aaaattcgtt ggtcatttgt tttcccctag atattttgtc tatcatacca
     3001 taaaaagcta aaaaaataaa gcggtttctt gaatgtggta agtcaatggt atatagtata
     3061 agtgatcaat ttattgatga aataggagat agattctact gatttataag cttataaagg
     3121 gggcttttta gttcacaact tataggaggt gtactatgaa aatcttaaaa cgttacatat
     3181 tggaactctg ttttatttta agttttgctt taccttttat aaaaggagcc aatgcagata
     3241 atggtagatg ctttgtggaa acctattacg gttttacttt tttgatggaa catgctattg
     3301 taacagctgt ctttatctgt tcgttcttaa ttgctttctt actaaaaaaa cgatgggcga
     3361 aatggattgc tgctggtagt tattgctttt tagtcctatg gattgcgaca gagggttatt
     3421 tcttccgcat gtcactagaa gatttgatac gactttggac aagtttggaa atcctgacac
     3481 aaacgtatca gttgggcttt tatctaaaca ttttgttagg aattttgttg ataataaagt
     3541 attttaaggt taagcaatag aaataataat ctgcctgatt atagatgata aactttttgt
     3601 ttttatctgg actgtgatat ttatagttct aaatgtttta ttatttataa gtgttgaaag
     3661 agattgaaga aaatggcttc gtgactcgct ttcttcggtc tttttcgttt tattatcaat
     3721 ttgtaaacga tttacaattt gagtcaaatt atggtaaaat agtgtcatga gtaaaatgta
     3781 ttatgcagaa aatcctgacg ctgctcacga cattcatgag ttgagagtag agttgttggg
     3841 acaaaaaatg acctttttaa cggatgcggg tgtttttagc aagaaaatag ttgactttgg
     3901 aagtcaacta ttgctcaagt gtcttgaggt caaccaagga gaaactgtcc ttgatgtagg
     3961 ctgtggttac ggacctttgg gtttgtcctt agctaaggct tatggagttc aggctactat
     4021 ggttgatatc aacactcgtg ccttggattt agctcggaga aatgctgaaa aaaataatgc
     4081 aaaagcgacg attttccagt ccaacatcta tgaacaagtt gaaggacatt ttgatcatgt
     4141 catttccaat cctcctatcc gtgcgggcaa gcaagtcgtt catgaaatca ttgagaaaag
     4201 taaagatttc ttggaaactg gtggggattt gacaatcgtc atccagaaaa aacaaggggc
     4261 tccaagtgct aagtccaaga tggaggatgt gtttggtaat tgtgaaatcc ttaaaaaaga
     4321 caaaggatac tatatcctta gaagtgtgaa agaatgagag cagttgattt aatccaaaaa
     4381 aaacgagacg gtcaagaact gacttcaagt gaaattgaat ggctgataga aggctatgta
     4441 tcaggaactg ttcctgatta tcagatgtct gcctttgcta tggctgttta ttttaaagga
     4501 atgacgactc gagaaatctc tgatttaacg atgaatatgg ttaagactgg gcaagagttt
     4561 gacctgtcag ccattgatgg tgtgaaagtt gacaagcatt ctactggtgg tgtcggcgat
     4621 aaggtaacct tgattttagc tcctcttgtt gctagcttcg gtgtgcctgt agcaaaaatg
     4681 agtggtcgtg gtcttggcca tacaggcgga acaattgata aattggagtc cattaggggc
     4741 tatcaagtag aacgtagtca agaggatttt attcgtcagg ttcaggatat tggagtatct
     4801 gtcattgggc aatcagacca gctggtcaaa gcagataagc ttctctatgc ccttcgtgat
     4861 gtgaccgcaa ctgtcgacac gattcctttg attgcgagtt cggtgatgag caagaaaatc
     4921 gcggcagggg cggatgctat tttgctagac gtgactgtcg gtgagggtgc cttcatgaag
     4981 acggttgatg aggcgcgtga gttggctcaa actatggtag atcttggtaa ggttgttgga
     5041 cggaagacag tagcagtgat tacggatatg agccagcctc tgggacgagc gattggaaat
     5101 cgtctggaaa tccttgaagc attggagatt ttgcaaggtc aaggacgtca ggatattacc
     5161 cactttattt gtgaattggc tcaaattatg cttggtttgg caaatgttaa caagactgtt
     5221 gaagaagttc gccaacatct tgagaatggt caagcactgg ctaagtttga ggaaatggtg
     5281 caagcccaag gtggagactt ggaagacctc tatcgtcctg taaatgtagc tcatgtggtg
     5341 gaaatccctg ctcaggaaac gggtgtcatt tcagctcttc cagctatgga ctttggtctt
     5401 tatgccatga ggttgggtgc tggtcgtgca gttaagtctg atgccttgga ctatgaaaca
     5461 ggaattgttt ttgaaaagaa gattggagac tccgttcaaa agggtgaaat tgttgcaaaa
//
LOCUS       DAVKAU010000077         5356 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVKAU010000077 DAVKAU010000000
VERSION     DAVKAU010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5356
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.077"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            40..933
                     /locus_tag="VWX48_001945"
     CDS             40..933
                     /locus_tag="VWX48_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEU9172504.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLGKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NVMYMPIIKTIEELDFVLSFEGINTVAVELVFQDLENPIISKKVIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     NNNKGELSCSKTLKRLHSLLH"
     gene            891..1952
                     /locus_tag="VWX48_001946"
     CDS             891..1952
                     /locus_tag="VWX48_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9172505.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTGFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNELKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            1969..2973
                     /locus_tag="VWX48_001947"
     CDS             1969..2973
                     /locus_tag="VWX48_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172506.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSETQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIEEKVTMYINPRDIMQF
                     "
     gene            2985..4679
                     /locus_tag="VWX48_001948"
     CDS             2985..4679
                     /locus_tag="VWX48_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9172507.1"
                     /translation="MRKSLNWKDCLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEADKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIAAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            4681..>5356
                     /locus_tag="VWX48_001949"
     CDS             4681..>5356
                     /locus_tag="VWX48_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU9172508.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     YNRLLIYLNTSGIKILEIQNGIGNLDEERQLNKIKSTKVSCYLSLKLNENFEHLKLME
                     EMHNIAG"
BASE COUNT         1841 a          741 c          982 g         1792 t
ORIGIN      
        1 gatacaatgt aattaacaat aaagatagga gaaaataatt tgaatccatt aaaagaatgc
       61 tatgaaaaaa acggtatact aattgcagca caccgtggta caaacggagg aaatatatta
      121 caaaacacat caaaagccta tttgaattcc atacgccata acgcagatat gtttgaggtt
      181 gatgtaattc gttcaaaaga tggagaattt tttgcatttc acgatgggca agaaccttta
      241 gtatttggtg aaaaaattga tattagaact ttgagttctg aagagatcca aagaaaggaa
      301 tgttttaatt cactgaatga acccatatta caaaagattg aaaaaatttc tgatgtatta
      361 aaaaattttg agggacagtc tttaataaat atagatagaa gttggtttta ctgggatacc
      421 ttcctaggta agttaaaaac atatccatct ttgaatcaag ttcttttaaa atcacctgta
      481 aaaaaagaat tattggaaat gcttagagac tctggtttga atgttatgta tatgccaatt
      541 atcaaaacaa ttgaagagtt agattttgtt ctttcatttg aaggaataaa tacagtagct
      601 gtcgaacttg tattccaaga tttagaaaat ccaatcataa gtaagaaagt aattgatgat
      661 ttacatgaaa aaggattact tatttgggtt aatgctttaa ccttaagtga ttcaattatt
      721 ctttcggcta agattgatga tgatacagct attgctcatg atggcgaatc ttgggggaaa
      781 ttggtttcaa taggatttga tattattcaa acagattggc cattattact ttatcaatat
      841 ctagttgaaa aaaataaaaa aataaaaaat aataataaag gagaactatc atgttcaaaa
      901 actttaaaaa gattgcattc acttcttcac taattttact tgctgcttgc tcaaacaatg
      961 cttcaaatac aaatcagtct actgatgaag gaagtgttga taaatctcaa gaaattgtaa
     1021 tctatacaaa ttcggcttct aatggacgtg cagattggtt acaaactaaa gcatcagagc
     1081 aaggatacaa tctccgtttg gtagatattt caggtggaga actagctgac cgtttgattg
     1141 cagaaaagaa taatgctgtg gctgatatgg taattggatt aaataaatta gaatttaacc
     1201 gtattaaagc tgaaaaactt cttgtaaaat actcaccaaa atgggctgat gaagtagata
     1261 gctctttggg agattctgaa gggtattatt caccaattgt aaatcaacca ttagttttga
     1321 ttggtaataa agatgctaaa atgccatccg actggacagg ttttactgat tcatcttata
     1381 aaggtaaata tggtatttca aaattaagta caggtacatc taagaacatc tttgcaagta
     1441 ttgtttcgag atataaagat gaaaaaggtg agttaggaat atctgatgaa ggttggaaag
     1501 ttgcaaaagc ttaccttaaa aatgcacacg tttatgcaga aggtgaagac tatatctctt
     1561 caattatgga taataataat gagctaaaat atagtatgat gtggggatct ggtgttctac
     1621 aaaatcaaaa agaacgtgaa tataaattcc aagtaatgtc accaaaagtt ggtgttcctt
     1681 atgtaactga acaagttggg attttaaata caagtaagaa gcaagcatta ttaaaagaat
     1741 ttgtagattg gtttggctct tcagaacttc aaaaagaatg gtctgataaa tttggttcaa
     1801 ttccagctaa taaaaaagct ctagagcaag caaaagatga actcaaacag tttgctaata
     1861 gtgttaaacc acaagaactt gactgggaat ttatcgggaa aaacatcgat tcttggattg
     1921 aaaaagcaca gcttgaattt gttgaacaat aatagttagg attaagtgat gattacattt
     1981 aaggatattc aaattaagta taatgatttt attgccatcg ataatctcaa tttaacaatc
     2041 aatgagggag agtttttcac atttttagga ccaagtggtt gtgggaaatc aacaactctt
     2101 cgtgcactag ttggattttt ggagccttca caggggcaaa tactagttga taatcaagat
     2161 attacgaatt tagatccaga aaaacgcgaa attggtattg tgtttcaaag ttatgcatta
     2221 ttcccaacaa tgactgtttt tgataatatt gcttttggtc taaaagttaa aaaagtttct
     2281 cctgaaatta ttaaagctaa agttcatgaa attgcgaaaa aaattaatat ctcagacgag
     2341 caactaaacc gaaatatttc tgaattatca gggggacaac aacagcgtgt agctttagca
     2401 cgtgcattag tattagaacc aaaaattctt tgtttggatg aaccgttatc aaacctagat
     2461 gccaaactac gagtttcgtt gagaaaagaa ttgaaacgat tgcaaaaaga actaggaatc
     2521 actactcttt atgtcacaca tgatcaagaa gaagcattaa cattatcaga taggattgct
     2581 gtgtttaata atggatttat tgagcaagtt ggcacgccgt atgatattta taatcaatcc
     2641 gaaactcaat ttgtctgtga ttttattggc tcaatcaata aaattagcca agaagttctt
     2701 aaaaaattac aaggcgagaa taaatacttt aaagaaactg aaggatacat acgcttagag
     2761 cgtgttaagt tagagaaaac ttcacctcaa gatttatcta taacaggggt aattagtgat
     2821 attgagttta atggtgtact tattaagtat aaagtagact tgtcgaatag tgaaagtatt
     2881 catattatcg aaaagaatga tggactatca cgtcatataa tcgaagaaaa agtcactatg
     2941 tacattaatc cgcgtgatat aatgcaattt taaggagatt gtgcatgaga aagagtctaa
     3001 actggaaaga ttgtctcata agattaggag ttttatggct aatctttgcc ctgattattt
     3061 atccaaatat tgaacttttg tctggagtgt tttataaaaa tggttcattt actctagagg
     3121 cattcaataa gattatacac tctcagagag cgatgagtag tatatttaat agctttattt
     3181 tggcgatttc aatggtcttt actgtaaata ttgttgggac attgattgtt ctactcacag
     3241 agtactggga tattaggggt tcaaaaatac ttaaattagg ttatatgagc tctctagtat
     3301 atggaggaat tgtattagcg acaggatata aatttgttta tggcgctaat ggtcttgtaa
     3361 ctaaaacgct ctcaagtata attccaggtc ttgcccctaa ctggtttcaa ggatttggtg
     3421 cagtattgtt tattatgaca tttgcttgta cctcaaatca cataatgttt ttaacaaatg
     3481 cagttcgtag tgttgattat catacaattg aagcagataa aaatatgggt gcaagtcctt
     3541 taaaagtttt ctttagtgtg gtttttccaa cttttaaacc tacgttattt gccttaacca
     3601 tcttaacttt tttgacaggt ctttcagcag tttctgctcc tttgatagta ggggggaaag
     3661 attttcaaac tattaaccca ttgattatca gtttcgctaa aactacaagt tcgagagatt
     3721 tagcagcttt actagctatc atgttaggtt tagcaactat tctattattg acacttttga
     3781 atcatgtcga aaaaggaggt aattatgtat ctgtttcgaa aaccaaggct agtattaaga
     3841 agcagataat ttcttctcca ttatggaata ctcttgctca cattgctgcg tatgtattgt
     3901 ttgcaatcta tatgttacca atagttttga taattctata ctcgtttaca gactcgttga
     3961 cgatcaagac gggaacttta gatctatcta aatttacgtt agcgaactat gctaatttat
     4021 ttacagatgc tcaatcattt cgtccttacc tagtcagcgt tgtttatgca attttagctg
     4081 cggtaattgc tacaattata gcaatagtaa tttcacgtat tgtacataaa aacaagagta
     4141 agttcgataa attctttgag tatggtgcac tgataccatg gatattgcca ggtacattga
     4201 ttgcactagg attaatgttc acttataata tacctcattt aatactattt aatttagttt
     4261 tagtaggaac agtaattatt ttacttattg catatactat tcaaaaatta ccattttctt
     4321 atagaatgat tcgggctgta tttttcagta tagataatga tatggaagaa gctgcacgta
     4381 gtatgggtgc atctagtttc tacactatgg tgcgagttat tataccgtat attttaccag
     4441 tcgtattatc agtagttgtg ttaaacttta attctttatt atctgactat gacttatctg
     4501 tattcttgta ccatccactt ttccaaccat tgggaatcgt tattaaacag tctactgatg
     4561 aaacagcaac tttaaatgca caggcaatga tgtttgttta ttctgtaatt ttaatgatta
     4621 tgtctagtgc agctctttat ttatcaagcc tattccaagg taaacgaggt aagagataat
     4681 atgaatcttt catacgaact gagtatttgg gaaatacttc ttaggtgctt tttagcgatt
     4741 cttttcggtg gcattgttgg ctatgagcga ggagtcaaaa accaagcagc agggattaga
     4801 acctacttac tagtttgttt gggaacttgt gttgtaatga tgacaaatca gttcatcact
     4861 agtcgttatg gtagcggtga tcctagtcga atgggagccc aagtaattag tggcttgggt
     4921 ttcctagggg caggaacaat catggtaact aatcaaaaag ttaaaggttt aacaacagca
     4981 gctggattat ggtcttcagc aactattggt ttagctatag gcattggttt ttatgaaggt
     5041 gctattttag ccggagttgt actcatagca gttttaactc tatttactcc tcttaaagat
     5101 tatttaaact cgaaaactaa aattgctgat tactacttgg tttttagttc tttagaaggt
     5161 tataatcgtt tacttatata tttaaataca tcgggtatta agattttaga aattcaaaat
     5221 ggtataggaa atcttgatga agaacgtcaa ttaaataaaa ttaagtcaac aaaagtgtcc
     5281 tgctatttat cattaaaatt aaacgaaaac tttgaacatt taaaattaat ggaagaaatg
     5341 cataatattg ctggtg
//
LOCUS       DAVKAU010000078         5044 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVKAU010000078 DAVKAU010000000
VERSION     DAVKAU010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5044
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.078"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..259
                     /locus_tag="VWX48_001950"
     CDS             <1..259
                     /locus_tag="VWX48_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="two pore domain potassium channel family
                     protein"
                     /protein_id="HEU9172509.1"
                     /translation="GSSILSVVEEKSFSDSLWWALVTVTTVGYGDIVPVSLLGKWLAV
                     LLMLVGIGTIGMLTSALTNFFVKDNPDEQIKLDKLKDELSS"
     gene            complement(608..1594)
                     /locus_tag="VWX48_001951"
     CDS             complement(608..1594)
                     /locus_tag="VWX48_001951"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU9172510.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALSFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            1788..4256
                     /gene="gyrA"
                     /locus_tag="VWX48_001952"
     CDS             1788..4256
                     /gene="gyrA"
                     /locus_tag="VWX48_001952"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU9172511.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQTQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLVITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            4256..5002
                     /gene="srtA"
                     /locus_tag="VWX48_001953"
     CDS             4256..5002
                     /gene="srtA"
                     /locus_tag="VWX48_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU9172512.1"
                     /translation="MSQKKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIV
                     WNTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIP
                     ELEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDN
                     AKNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERII
                     VKGDLKETKDYSQTSNEILTAFNQPYKQFY"
BASE COUNT         1582 a          868 c         1113 g         1481 t
ORIGIN      
        1 aggaagttca attttatctg tagttgaaga aaaatccttc tcagatagtc tttggtgggc
       61 tcttgtgaca gtaactactg ttggttatgg tgatattgtt ccagtttccc ttttggggaa
      121 atggctagca gttttactga tgcttgtcgg tattggaaca atagggatgc taacaagtgc
      181 tttgacgaac ttttttgtaa aggataatcc agatgaacag ataaaacttg ataaactcaa
      241 agacgaatta tcgagctaaa gaatattaat agagaaacaa tctgaaaaaa tcgaagaact
      301 acattgaatg ataaaagact tagttgaaaa aatatcataa aggtgagaca aaataaaact
      361 tgattcgagg agaaatcaag taagtcttga cacaatagaa cgcatattat caggtataaa
      421 aacttgatac tatgcgtttt atagagaaat aaaataaaat ctgaacaaat caattaggaa
      481 tttaaagcat tttataacaa cgttttagag taatggggtg ctatttcaac ttcaacctac
      541 tataatacag aaaaaaatac agaaaaaaac aactccctga tgattcaagg agttgtctat
      601 agttaaatta gtttttagaa gcttcttgga attctggatt tttccatgct tcgtcaataa
      661 tagcttgcaa ttctttagca gatgcttgca ttttttgagt ttctgcatcg ttcaatggaa
      721 tgtttactgg acgaacgata ccatgtgcac caacaacagc tggttgaccg ataaagacat
      781 tctcaactcc gtattgacct tcttggaata ctgaaagtgg aagtactgcg ttttcatcgt
      841 caaggattgc tttagtgata cgagcaaggg ctactgcgat accgtagtat gttgcacctt
      901 ttttgttgat gattgtgtag gctgcatcac gaacaccttc gaacaattca atcaattcag
      961 cttcttgaac attttgagtg tctttaagga attcttcaag gtttacacca gcgatgttag
     1021 cgtgtgacca aacagcgaac tcagagtcac cgtgttcacc catgatgtag gcgtgcactg
     1081 aacgagcatc cacatccaat ttttcagcaa gtgcttgacg gaaacgagct gagtcaagtg
     1141 aagtacctga accgataacg cgttctttag ggaaaccaga gaatttccaa gttgagtaag
     1201 tcaaaacgtc aactgggtta gcagcaacaa ggaagatacc tttgaaacca gattcaacaa
     1261 cttgagttac gattgatttg ttgatagcaa ggtttttacc tacaaggtca agacgagttt
     1321 cacctggttt ttgaggtgca cctgcagtga tcacaacaag gtcagcgtct gcacagtcag
     1381 agtattgagc tgcatagatt tttttaggtg aagtgaagga aagggcgtga ctaaggtcaa
     1441 gcgcatcacc aacagctttt tcatgcaatt gtggaatttc gataattcca agctcttgtg
     1501 caattccttg gttaacaagt gcaaaagcgt aagatgaacc tacagcacca tcaccgacaa
     1561 ggataacttt tttgtgttgt ttagttgaag tcattgtttt aaacatctcc ttaattttat
     1621 taggggattt tccctagaca acttcattct atcactttta aaaaactttg tcacgaatat
     1681 gccttatagt tctctatgta aacgttttag tggtttagag gctgaaatag atgggaattt
     1741 atggtataat gttgttactt actaattgtg aaatgaggca tttattaatg caggataaaa
     1801 atttagtgaa tgtcaatctg acaaaggaga tgaaggcaag ttttatcgac tacgccatga
     1861 gtgttatcgt agcgcgagct cttcctgatg ttcgagatgg cttaaaacct gttcaccgtc
     1921 gcattctcta cggaatgaat gaattgggtg tgaccccaga caaaccccat aaaaaatctg
     1981 ctcgtattac aggggatgtc atgggtaaat atcacccaca cggggattcc tctatttatg
     2041 aagccatggt ccgtatggct caatggtgga gctaccgtta catgcttgta gatggtcatg
     2101 ggaattttgg ttccatggat ggagatagtg ctgccgctca acgttatacc gaggcacgta
     2161 tgagcaagat tgctctggaa atgcttcgtg atatcaacaa aaatacagtt gatttcgttg
     2221 ataactatga tgccaatgaa cgggaaccct tggtcttgcc agcgcgtttt ccaaaccttt
     2281 tggttaatgg agcaactggt atcgcggttg ggatggcaac caatattcca cctcataatc
     2341 tgggtgaaac cattgatgca gtgaagttgg tcatggataa tcctgaagtg actaccaagg
     2401 acttgatgga agtcttgcct ggaccagatt ttccaactgg tgctcttgtc atggggaaat
     2461 caggtatcca taaggcttat gaaacaggta aaggttcgat tgtcctacgt tctcgtacag
     2521 agattgaaac gactaagact ggtcgtgagc gcatcgttgt aacagaattt ccttacatgg
     2581 tcaataaaac caaggtgcat gagcatattg ttcgcttggt tcaggaaaaa cgcattgagg
     2641 gtatcacagc agtacgtgat gagtcaaacc gtgaaggtgt tcgatttgtt attgaagtca
     2701 agcgcgacgc ctcagccaat gttattctca ataacctctt caaaatgacc caaatgcaaa
     2761 ccaattttgg tttcaatatg ctcgctatcc aaaatggtat accgaaaatt ttgtctcttc
     2821 gtcagatttt ggatgcttat atcgagcacc aaaaagaagt ggttgttcgt cgtacacgtt
     2881 ttgataagga aaaagcggaa gcgcgcgctc atatcttaga aggtctcttg attgcgctag
     2941 accatatcga cgaagtgatt cgtatcatcc gtgctagtga aacggatgcg gaagctcaag
     3001 ctgagttgat gagcaagttt aagctttctg aacgtcaaac tcaagctatc cttgatatgc
     3061 gtcttcgtcg tttgacaggt ttggaacgcg ataagattca atctgagtat gatgacctct
     3121 tggctctgat tgcggattta gcagatattc ttgctaagcc tgaacgtgtt tctcaaatta
     3181 tcaaagacga attggatgaa gttaaacgta aattttctga taaacgccgt acagagttga
     3241 tggttggaca ggtcttgagt ctcgaggatg aggacttgat tgaagaatcg gatgtcttga
     3301 ttaccctttc taacagaggc tacattaagc gtttggatca ggacgagttc actgctcaaa
     3361 aacgtggggg tcgtggtgtc caaggaacgg gagtgaaaga tgatgacttt gttcgtgagt
     3421 tagtgtcaac tagcacccat gatcatctgc tcttcttcac aaacaaggga cgtgtctatc
     3481 gtcttaaagg ttatgaaatt cctgagtatg gtcggactgc caaagggcta ccagtagtca
     3541 atctcttgaa attggatgaa gacgaaagta ttcagacggt tatcaatgtt gagtctgatc
     3601 gcagtgatga tgcttatctc ttctttacaa cccgtcacgg tattgtgaag agaaccagtg
     3661 ttaaggagtt tgccaatatt cgtcaaaatg gtctcaaagc gctgaattta aaggatgaag
     3721 atgagttaat caatgtcttg ttggcagaag gagatatgga tattatcatt ggtaccaagt
     3781 ttggttatgc agttcgcttt aatcaatcag ccgttcgtgg tatgagccgt atcgccactg
     3841 gtgtgaaagg tgttaacctt cgtgaaggag acacagttgt tggtgccagc ttgattactg
     3901 atcaagatga ggttcttgtt atcacagaaa aaggatatgg taagcgtaca gtcgctactg
     3961 aatacccaac aaaaggtcgt ggtggtaagg gaatgcagac agctaaaatt accgaaaaaa
     4021 atggcttgct ggccggtctt atgactgttc aaggggatga ggatttgatg attatcactg
     4081 atacaggtgt catgattcga accaatcttg ccaatatttc acaaacagga cgtgcaacta
     4141 tgggagttaa agtaatgcgc ctggatcaag atgctcagat agtgactttc acaacggttg
     4201 cggtggcaga aaaagaagaa gttgggacag aaaacgaaac agaaggtgaa gcataatgtc
     4261 tcaaaaaaaa aataataaaa agaaaaacaa gcgaaaaaat ttgctgacaa atatcctagc
     4321 aggatttctg atattactgt cactggcttt gatttttaat actcaaattc gaaatatttt
     4381 catagtctgg aataccaata agtatcaagt tagccaggta tcaaaagaaa aattagaaga
     4441 aaatcaggat acagaaggca attttgactt tgattctgtc aaagctatct cttcggaagc
     4501 tgttctaact tctcaatggg atgctcaaaa attaccagtt attgggggaa ttgcaattcc
     4561 tgaattggaa atgaatttgc cgatttttaa aggacttgat aatgttaatc tcttctacgg
     4621 agctggtaca atgaaacgcg agcaagtaat gggagaagga aattatagtc tagctagtca
     4681 ccatatcttt ggtgttgata atgctaataa aatgttattt tctcctttag ataatgctaa
     4741 aaatggcatg aagatttatc taaccgataa aaataaagtt tatacttatg aaatacgtga
     4801 agtcaaacgt gtgacaccgg atcgtgttga tgaagttgat gatagagatg gggtcaatga
     4861 aatcacatta gtaacctgtg aagaccttgc tgctacagaa cgtattattg tcaaaggtga
     4921 tttgaaagaa acaaaagatt attcacaaac atctaatgaa atcctaacag ctttcaatca
     4981 accatataaa caattttatt aatacaaatc agtgaaatca tggatttcac tgatttttta
     5041 agat
//
LOCUS       DAVKAU010000079         4953 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVKAU010000079 DAVKAU010000000
VERSION     DAVKAU010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.079"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(6..518)
                     /locus_tag="VWX48_001954"
     CDS             complement(6..518)
                     /locus_tag="VWX48_001954"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU9172513.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            complement(605..1363)
                     /locus_tag="VWX48_001955"
     CDS             complement(605..1363)
                     /locus_tag="VWX48_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9172514.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            1571..1717
                     /locus_tag="VWX48_001956"
     CDS             1571..1717
                     /locus_tag="VWX48_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172515.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            complement(1864..2994)
                     /gene="ugpC"
                     /locus_tag="VWX48_001957"
     CDS             complement(1864..2994)
                     /gene="ugpC"
                     /locus_tag="VWX48_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU9172516.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(3278..3363)
                     /locus_tag="VWX48_001958"
     tRNA            complement(3278..3363)
                     /locus_tag="VWX48_001958"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3327..3329),aa:Leu,seq:aag)
     gene            complement(3445..4020)
                     /locus_tag="VWX48_001959"
     CDS             complement(3445..4020)
                     /locus_tag="VWX48_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9172517.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            complement(4020..4808)
                     /gene="codY"
                     /locus_tag="VWX48_001960"
     CDS             complement(4020..4808)
                     /gene="codY"
                     /locus_tag="VWX48_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU9172518.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
BASE COUNT         1505 a         1071 c          809 g         1568 t
ORIGIN      
        1 tttcattaat aatgcataag aactttgtag tcgtagtcac caattttttc acggccgttc
       61 aattcatcca attcaacaag gaaggcacaa cctgccataa caccaccaag tttttcaatc
      121 atctcgatag ttgccttaac agttccacct gtcgccaaaa ggtcatctac aataagaaca
      181 cgttgacctg gcttaatggc atccgcgtgc atagtcaagg tatcgacacc gtactctttt
      241 tcatagtcag cagaaataac ttcgcgtggc aatttacctg gcttacgaac aggcgcaaaa
      301 ccaattccca actcaaaggc aactggacaa cccacgataa atccacgagc ttcaggtccc
      361 acgatcatgt cgactttctt gtcagtagca tactgaacga tttcacgaac agcgtagcta
      421 taagcatttc catcagccat caaaggacta atatcacgga aggtaatgcc ttcctttgga
      481 taattttcaa ttgttgcaat gtaatctttt aaattcatct ttttctttct ttcaaagttt
      541 tttactctct attatagcat attttttaag aaagaaaaaa ggaaaagtta acttcaataa
      601 ttatctaacg ttttgacgat ttataactag ccatcgcaat aaagcccaat ttctgtttat
      661 tcttagcaaa cattttatac atagttaaaa actgctttct attctccttt ttacaagcat
      721 ttacacaaat tttcaaagtt cctagcaaac cttcgtcata aatcataccc gataatttca
      781 ttaatgtcat ttcaccagtc aatgctttca catcacaata acctgattct atcatcacct
      841 gttcccaacc atcttgagtt aaaggaccta catttacatg aattgcttgt gataattcct
      901 gtctgataga ctctttagct tccttaagaa gcacatcatg tgtcaagaga agacctccag
      961 gttttaatac ccttagatat tccattacac attttttctt agcttgatcg gcttgcatag
     1021 tcagcatagc ttcatttata acaatatcaa aactagcatc ttgataagga agtttcattg
     1081 catttgctct ttcaaaactg attaaatgag caacacctgc cgttccagca gattttttag
     1141 ccacttctaa agcttgagca tccatatcaa cagcagttat cttgcaacca aaacgctgtg
     1201 ccaactcaat tgctgtagtt cccctattac acgcaacctc tagtattctc ttttcttttg
     1261 aaaatcctcc ttctgcaatt aaccaatctg tggcacgctt tccacctgga cgtaagcgtt
     1321 ttttccccaa ttttgctaaa aacttatgac ctgcttctga catttgaaca cctctgtttt
     1381 ttcttcatta taacacaaaa tgatattatc tgacaattct aatctattat ttgataaact
     1441 agaatcaaaa gcatacaagt caccataact atagcataaa tttattatta cctctctagt
     1501 tcgaattcaa ttgctcacgt agtttacgca tatagcttca cttgtagatg gtacccacaa
     1561 ataatactca atggaaatca aagagcaaac taggaaacta gccgtaagct gctcaaagta
     1621 catctttgag gttgcagata aaactgacga aatcagtaat catacgtacg gcaaggcgac
     1681 gttgacgtgg tttgaagaga ttttcgaaga gtattaaaga gcatcacaat atagatgcat
     1741 aatatgactt ccctagcaaa aaggagagaa gcattttgtt tctctcccta gattaactga
     1801 tatctctcca ctacaattga taaagagata tcttttcttg tagtgctttg aattttattt
     1861 attttagtag attgtttttt cagtttctac atcgaagaag tgtgctttgt tcaagtcaaa
     1921 tccaagctca actgttgcac ctgtttgcaa gtagtcacga gcatcaactt ttgcaacaaa
     1981 ctcgtcttta ccaacttggc agtaaaggtg agattctgaa ccaagcagtt ctgatacaga
     2041 gatagtcgct tttacaacac agtctgggaa tgtttcaagg aaagcaggtt ctgcattcac
     2101 gtcttctgga cggataccaa agatcaattc ttttccttcg tagccttttt cacgaagaac
     2161 tttcaatgct ccttctggca ctttcaaacg gaaaccgtca gaaacaattt cgctaccaac
     2221 caatttcacg gtgatgaagt tcatagctgg gcttccgatg aatcctgcaa cgaatttgtt
     2281 aactggattt ttgtaaactt cttgaggagt accgatttgt tctacacgtc cgatagtacc
     2341 tgtaccagca gggttcttag tagctgacat aataacgata cggtctgcaa gtgtcatcgc
     2401 ttctgtttgg tcgtgagtta catagatagt tgtagctccg atacgacggt gaattttagc
     2461 gatttcagca cgcattgata cacgaagttt ggcatccaag tttgacaaag gttcgtccat
     2521 caagaatact ttcgcatcac ggacaatcgc acgccccatg gcaacacgtt gacgttgacc
     2581 acctgaaagg tcagctggtt tacgttccaa gaattctttc aatccaagta tttcagctgc
     2641 ttcttgaaca cgtttgttaa tgtcttcttt gctgtattta cgcaatttca aaccgaaagc
     2701 catgttgtca taaacagtca tgtgtgggta aagagcgtag ttttggaata ccatggcgat
     2761 atcacggtct tttggagcta cgtcgttgac aactacgcca tcgatagatg cagtaccttc
     2821 tgtaatgtct tcaagaccag caatcatacg gagtgtagtt gatttaccac atcctgaagg
     2881 tcctacgaaa acgataaatt ctttatcttt gatgttcaag ttgaaatctt caactgaata
     2941 gtgttcgctg tttggatatt ttttgtaaat atttttaaga ttcaattcta ccatgaggtg
     3001 aactcctttt gtcttttaat aattatatta tatatgaaaa cgctttatat ttctatggca
     3061 agatgaccaa aaaaataaac aagttctgtg caacttgcac aaaactttag agaatatcgg
     3121 agaatttgaa gaagataatc tttattattc ttctatagac aaaagcagaa acaaggatca
     3181 gttttcccat attttcgctg attctccact acatttgact ggattctaat tttttagaga
     3241 aatacaaaag agctagcttt agctaactct tttcctatgc ggagagaggg acttgaaccc
     3301 tcacgaccta aagcggtcac aggatcctta gtcctgcgcg tctgccaatt ccgccatccc
     3361 cgcatcgatt actttactag tatatcaact tttgggatgc ttgtcaacac tttttttcaa
     3421 attttttcat tttcaccaac caggttactc agaaagttca tttagatttt catctactaa
     3481 cttagctccg agtgtatttt tgaaatgacc tagggcaaat tgatgatttt caggccagat
     3541 ggaagcaaca gctggtttaa caatctcgat gtcatatcct agattatagg catctatagc
     3601 tgtatgtagg acacagatat ccgtcaagac acctgttaag ataacggtag acactctacg
     3661 ctctctcaaa cgaatatcta ggtcagtccc tgaaaaagct gagtaatggc gtttatccat
     3721 ccaaaagaca cgactgtctg aaccatgctc ttgataaaag atccccaaat ctccatataa
     3781 attccgtcca ctcgtcccaa tcagattatg aggaggaaat aacttacttt ccggatggaa
     3841 acaatcgttt tcttcatgag catcaatagt aaagaagata taatctcctc gttcaaaagc
     3901 taatcgagtt accttgctga tggcatccga aatcgcctga gctggagcac ctgctgttag
     3961 tttcccacta tcagcaacaa aatcttctgt ataatcaatc gaaattaaag cctttgtcat
     4021 tagtaatctc ttttcttcac ttcttcaaaa atatctgaaa tcaagacctt aagataggtt
     4081 cccttcattc caagtgagcg actttcaata atccccgcag actcaagttt acgaagagca
     4141 ttgacaatca cagagcgagt gattccgata cgatctgcaa tcactgacgc agtcaacttc
     4201 ccttcatttc catttaattc ccctaaaatt gctgaaacag cacggagttc ggagtaagaa
     4261 agggtattga ccgccatggt gacagcagta cgacgacgaa tatttttctc atcttcttca
     4321 cgttggaagt taagaagctg aatcccaaca acggtactgg caatctcaac aagaaccaag
     4381 tcctcatctt cgaatttttt atcattacgc caaataatca aagaaccaag gcgaatcccc
     4441 gatacatgaa tcggtgcaat agtcgtcaag ccatctggaa aatcatctct actctcaaca
     4501 gggaaaatac tcatatcatg ctcaacaggc aagtttgctt ctgtttcgta aatcatatta
     4561 gccccttgaa cgtagtcatc tgggaaaatc ttagtttgga agaattgctc tacgcgatct
     4621 gtatttgttt tataacgcat aaaatagcca agcagacgtc ccttactatt gataatgcag
     4681 gcattgcaat gaataatatc cgctaactga cgcgtaatag cgttgtaagg gagctcatcc
     4741 tgcaactgct cctctgagcg tttcaaaatt gatgtaattt ttctagtttt ttctaataaa
     4801 tgtgccattt ttcacctcga atttaatcgc tatcattata acataaaaac gtctcttttt
     4861 caataattat ctgaaaattc cttattgact tgcattgact tacaatttaa ttaaaaacca
     4921 gaatattttt aattaaattg ttccttttct att
//
LOCUS       DAVKAU010000080         4891 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVKAU010000080 DAVKAU010000000
VERSION     DAVKAU010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4891
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.080"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            749..1036
                     /locus_tag="VWX48_001961"
     CDS             749..1036
                     /locus_tag="VWX48_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172519.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIFDGKAVEVTLREPYSRDILQVVKSIKQRQKLIAYRYKEGKLLFVKKEV"
     gene            1194..1490
                     /locus_tag="VWX48_001962"
     CDS             1194..1490
                     /locus_tag="VWX48_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000941983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172520.1"
                     /translation="MLQSPYAIDTINLKKDFLEKPIDIEKFKAFLEKEEIPLAIAWQG
                     DSLHFYTKDRSILDNHLDHLLEKMVNDPEKLSDFSMDKSLDDTIDEAKSQITFK"
     gene            complement(1724..2770)
                     /locus_tag="VWX48_001963"
                     /pseudo
     CDS             complement(1724..2770)
                     /locus_tag="VWX48_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            3026..3834
                     /locus_tag="VWX48_001964"
                     /pseudo
     CDS             3026..3834
                     /locus_tag="VWX48_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            3851..4429
                     /locus_tag="VWX48_001965"
                     /pseudo
     CDS             3851..4429
                     /locus_tag="VWX48_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            4442..4612
                     /locus_tag="VWX48_001966"
     CDS             4442..4612
                     /locus_tag="VWX48_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172521.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT         1608 a          776 c          941 g         1566 t
ORIGIN      
        1 tcgttccaat atgtgcacgt tggaatgtta gtgcttatat ggggggaaca gaatcctctc
       61 ttgattgaag acaagctagt cattaggcta gtttgtcttt ttgtcaactg tagtgggttg
      121 atataatagt attagtgagt gggataaaag tttcatttag tttattcagt acaaatttaa
      181 cgggtcaaga tttatatact ggtggtgttt ttggggctga gagaagtatc ttgattttat
      241 gtgtggtttt tatacttaca gttgttctgc tccaaagagc ttgtagagaa gaattagctc
      301 ataaaggaga ttgattattt tgatatcaaa aaaatgcaca ggataacctg atgcattttt
      361 ttagcgacaa tgcttgctac ttccttctgt cgaatttaga caattttaaa taaaagaatg
      421 aaatattccc tactgtattt ttagacgaag aacgttagtt aataatactc aaatttattt
      481 caaactcttt gattagtatg aatttagctc tacagaaaaa taaaaaatgt gataaaaatt
      541 tcaactactc ttatctataa taaagctacc tgttctttga aaattgaatc cactccgtct
      601 tgattagcgt gcctgtgtaa gtagggactg agagtatttc cctgtgaagg gcaactggca
      661 caagacgtgt gtgagaattt tctaacagac acggagttta tcgtttccag actcaaacga
      721 tgcgacaaac tagataaagg agttaatcat gaaggtagta aacttgtatg atttgaaaca
      781 aatgggaaat aaaggtggtt gtaccatcca attgattcat cactttcctt ttggtatggg
      841 cttaggacat ctcaaaaagg actacattga atttaaacgt gttggtatct ttgatgggaa
      901 agcagtagaa gttactcttc gagaacctta ttcgagagat atactgcagg ttgtcaagtc
      961 gattaagcaa cgtcagaaat tgatagctta tcgttataaa gaaggaaagc tgctatttgt
     1021 taagaaggag gtctgagatg tcctctgaac aacaggaacg aatggcagtt caatatgctg
     1081 agcgtagtct tttatttact gtaaaaggtc ttttaaagat actagaatgg tctagatgtc
     1141 aggctttaga acaggattcc gcctataaga taggggtgta gaaattagaa gaattgctac
     1201 aatctcccta tgcgattgat acgattaatc tgaaaaaaga ttttttagaa aaaccaattg
     1261 atatagagaa atttaaagct tttttagaaa aagaagagat tcctttagcc atcgcttggc
     1321 aaggggattc tctgcatttc tacacgaaag accgttcgat tctagacaat catttagacc
     1381 atctgttaga aaaaatggtg aatgatcctg agaaattatc tgatttttcc atggataagt
     1441 cattagacga tacaattgat gaggctaaat cccaaattac ctttaaataa tagagtatcg
     1501 caatttgatt gcggaactct tgtttaatga gagttgagat aatataaagg cgataataat
     1561 tgggagaata attatattcc ccgccaaacc ccactaagtt tttatcttgg tggggtttct
     1621 tggtacgact tacccttatt aaaattatta tgtagttttt ttgaatttag catcatcaag
     1681 attctgattg ttttgatatt gacttttcat ttatttctaa tactcatctg ttttcaaaaa
     1741 gcattctagt ccatctccga ttaacgatgg actttatcac ctccttctcc agtccttgta
     1801 tgacatcttg aagttgattc atgacatctt ccaaagttcg aaaggcctta ttcttaaatc
     1861 cacgtttacg aatctctttc cacacttgtt caatgggttc atctctggtg tgtatggagg
     1921 aataaaggta aaaccaatat tagtcggaat ctttaaggta cttgatttat gccatatagc
     1981 attgtccata acgagtaaaa gataatcatc tggataagct tgtgaaagct cttctaaaaa
     2041 ggagttcatc cactcagtat tacatccacc agctattaag aaaaatgatt cgcctgtatg
     2101 ggcatcaaca gctccataac aatagtgaaa ttctcgtata tagtgactat ggacatgtgg
     2161 acctactcct attggagacc aacaagatcc cagtttactg attctaccga aaccagcctc
     2221 atcttggtac atcaagcgaa ccttatgaaa acgtctactg gttttaaatc gctttcttgt
     2281 cttcttgaat tgagatttta tttttagacg cgacaatggt ttgagcgtct gctttcttag
     2341 gatgttctgg acgtggcata atatttcgcc agccatggcg cttcaacagt tgatagaagg
     2401 catcacgtgt gtaggaacga cctaactcct ttttataagc ctgaaataag gcatcaattg
     2461 taacaaattc tcctgcctct gtagccttca aatggcgggc aagaaagact ttctcttcct
     2521 caactgtcat atatgcatgg ttacgaccac cacgtgtttc ttgaaggaga gagtcgagtc
     2581 cgaactcctc atattttttt acattttgct aaatcgttgt ttaattacag tctaaaagct
     2641 ctataatctc tttataagat ttgcccatca gacgaaatag aacgatttga aggcgtttat
     2701 gatatttagc tgtacgagag tcttttaaaa gtgttttgat ggtttggatt tcttctttag
     2761 ttgatttcat atcactattg tataatgctt tttgatttta gtctagtata aatagcgaga
     2821 aatatctatc ctatcttcta gaatgtcttc caaacgagga aactctcgta aacaaagagg
     2881 ttttagaggc ctatttaccg tggactaaag ttgtacaaga aaagtgcaaa taagaaatct
     2941 ccagattagg aactatccgt gagttctcta gtctggagat ttttcaatag acttcctgcg
     3001 aaacaaaata tggtataata gttctatgaa tgatgaagca agtaaacaac taaccgatgc
     3061 acgatttaag cgtcttgttg gtgttcaacg cacgactttt gaagagatgt tagctgtatt
     3121 aaaaacagct tatcaactta aacacgcaaa aggtggacga aaacctaaat taagcctaga
     3181 agactttctt atggccactc ttcaatatgt gcgagaatac cgcacttatg aagaaattgc
     3241 ggctgatttt ggtatccacg aaagcaactt actccgtcgg agccaatggg ttgaagtaac
     3301 tcttgttcaa aggtggtgtt acgatttcaa gaactcctct cagttctgaa gacacggtaa
     3361 tgattgatgc gacggaagta aaaatcaatc gccctaaaaa aaaaacaatt agcgaatgat
     3421 tctggtaaaa agaaatttta cgctatgaag gctcaagcga ttgtcacaag tcaaggaaga
     3481 attatttctt tggatatcac tgtgaactat tgtcatgata tgaagttgtt caaaatgagt
     3541 cgcggaaata tcggacaagc tggtaaaatc ttggctgaca gtaattatca agggctcatg
     3601 aagatatatc ctcaagcaca aactccacgt aaatccagca aactcaagcc gctaatagct
     3661 gaagataaag cctataacca tgcactatct aaggatagaa gcaaggttga gaacatcctt
     3721 gccaaagtaa aaacgtttaa aatgttttca acaacctatc gaaatcatcg taaacgcttt
     3781 ggattacgaa tgaatttgag tgctggtatt atcaatcatg aactaggatt ctagttttgc
     3841 aggaagtcta ttatcaaaaa taccatcagg attatataag attgatacag gaaaagtttt
     3901 atttgatggt gtaaatatta atcaaataga taaaaaaata ttaagtcaaa atttaggagt
     3961 agttccacag gattcgtttt tattgaacag aagtattctt gataacataa ctttaaagca
     4021 cgaagttact tcacaaaaga tagaggaagt ttgtaaagca gttcaaatct atgatgaaat
     4081 catggctatg ccgatgaaat ttaatactat catctcagag atgggttcaa atatttcagg
     4141 tggtcaaaga caacggatag cactggcacg tgcattaata aataatccta gtattgtaat
     4201 tttagatgaa gcaactagtg ctttagacac tattaatgag gaaagaataa caaagtatat
     4261 aaaaagtcag ggctgtactc aaataattgt agctcataga ttgtcaacga ttaaggatgc
     4321 ggatattatt gttgtaatga aaggtggtaa gattgttgag tcaggaaatc ataagtactt
     4381 aatggatctt ggtggagagt actacagctt atatacaaaa aggaaatgag gtgtaaagaa
     4441 aatgaagaaa gaaaatgaat atgtaatttt aacaacagcc tcactagggg tgatgattgg
     4501 aatagtgttt gcaatttttt tagattttcc agttgaatat ggtatttctt taggattgtt
     4561 gaatggaata gtattgggtt cgctgattgt ttacaaaaac aataagaatt aagcataatt
     4621 ttttgctgta aactaaggag tagagatggc tatagttgaa attataaatc taacaaaaag
     4681 ctttaaagat attgaagtta ttcataacac ttaaataata gagcaactac agtagtagct
     4741 taaaaacatg attaaatcgc tattcttagg agtagcgttt tttctttttg tttaatactc
     4801 tttgaaaatc tcttcaaacc acgtcagctt tgccttgccg tactcaagta cagcctgcga
     4861 ctcgcttcct agtttgctct ttgattttca t
//
LOCUS       DAVKAU010000081         4854 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVKAU010000081 DAVKAU010000000
VERSION     DAVKAU010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.081"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            146..1691
                     /locus_tag="VWX48_001967"
     rRNA            146..1691
                     /locus_tag="VWX48_001967"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1743..1815
                     /locus_tag="VWX48_001968"
     tRNA            1743..1815
                     /locus_tag="VWX48_001968"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1776..1778,aa:Ala,seq:tgc)
     gene            1940..4841
                     /locus_tag="VWX48_001969"
     rRNA            1940..4841
                     /locus_tag="VWX48_001969"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1363 a          994 c         1433 g         1064 t
ORIGIN      
        1 tcgcttgaga gaagcaagtg acaaagacct ttgaaaactg aacaagacga accaatgtgc
       61 agggcgctac aacataagtt gtagtactga acaatgaaaa aaacaataaa tctgtcagtg
      121 acagaaatga gtaagaactc aaacttttaa tgagagtttg atcctggctc aggacgaacg
      181 ctggcggcgt gcctaataca tgcaagtaga acgctgaagg aggagcttgc ttctctggat
      241 gagttgcgaa cgggtgagta acgcgtaggt aacctgcctg gtagcggggg ataactattg
      301 gaaacgatag ctaataccgc ataagagtag atgttgcatg acatttgctt aaaaggtgca
      361 cttgcatcac taccagatgg acctgcgttg tattagctag ttggtggggt aacggctcac
      421 caaggcgacg atacatagcc gacctgagag ggtgatcggc cacactggga ctgagacacg
      481 gcccagactc ctacgggagg cagcagtagg gaatcttcgg caatggacgg aagtctgacc
      541 gagcaacgcc gcgtgagtga agaaggtttt cggatcgtaa agctctgttg taagagaaga
      601 acgagtgtga gagtggaaag ttcacactgt gacggtatct taccagaaag ggacggctaa
      661 ctacgtgcca gcagccgcgg taatacgtag gtcccgagcg ttgtccggat ttattgggcg
      721 taaagcgagc gcaggcggtt agataagtct gaagttaaag gctgtggctt aaccatagta
      781 ggctttggaa actgtttaac ttgagtgcaa gaggggagag tggaattcca tgtgtagcgg
      841 tgaaatgcgt agatatatgg aggaacaccg gtggcgaaag cggctctctg gcttgtaact
      901 gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgct
      961 gtaaacgatg agtgctaggt gttagaccct ttccggggtt tagtgccgta gctaacgcat
     1021 taagcactcc gcctggggag tacgaccgca aggttgaaac tcaaaggaat tgacgggggc
     1081 ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc
     1141 ttgacatccc tctgaccgct ctagagatag agttttcctt cgggacagag gtgacaggtg
     1201 gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca
     1261 acccctattg ttagttgcca tcatttagtt gggcactcta gcgagactgc cggtaataaa
     1321 ccggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg
     1381 tgctacaatg gctggtacaa cgagtcgcaa gccggtgacg gcaagctaat ctcttaaagc
     1441 cagtctcagt tcggattgta ggctgcaact cgcctacatg aagtcggaat cgctagtaat
     1501 cgcggatcag cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac
     1561 cacgagagtt tgtaacaccc gaagtcggtg aggtaaccgt aaggagccag ccgcctaagg
     1621 tgggatagat gattggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga
     1681 tcacctcctt tctaaggata aggaactgcg cattggtctt gtttagtctt gagaggtctt
     1741 gtggggcctt agctcagctg ggagagcgcc tgctttgcac gcaggaggtc agcggttcga
     1801 tcccgctagg ctccattggt gagagatcac caagtaatgc acattgaaaa ttgaatatct
     1861 atatcaaata gtaacaagaa aataaaccga aaacgctgta gtattaataa gagtttatga
     1921 ctgaaaggtc agaaaataag gttaagttaa taagggcgca cggtggatgc cttggcacta
     1981 ggagccgacg aaggacgtga caaacgacga tatgccttgg gtagctgtaa gtaagcgatg
     2041 atccagggat ttccgaatgg gggaacccaa caggtaatac ctgttaccca catctgttaa
     2101 ggatgtgagg aggaagacgc agtgaactga aacatctaag tagctgcagg aagagaaagc
     2161 aaaagcgatt gccttagtag cggcgagcga aacggcagaa gggcaaaccg aagagtttac
     2221 tcttcggggt tgtaggactg caatgtggac tcaaagatta tagaagaatg atttgggaag
     2281 atcagccaaa gagagtaata gcctcgtatt taaaatagtc tttgtaccta gcagtatcct
     2341 gagtacggcg ggacacgtga aatcccgtcg gaatctggga ggaccatctc ccaaccctaa
     2401 atactcccta gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa agcaccccgg
     2461 gaggggagtg aaatagaacc tgaaaccgtg tgcctacaac aagttcgagc ccgttaatgg
     2521 gtgagagcgt gccttttgta gaatgaaccg gcgagttacg ttatgatgcg aggttaagtt
     2581 gaagagacgg agccgtaggg aaaccgagtc tgaatagggc gccttagtat catgacgtag
     2641 acccgaaacc atgtgaccta cccatgagca ggttgaaggt gcggtaagac gcactggagg
     2701 accgaaccag ggcacgttga aaagtgcttg gatgacttgt gggtagcgga gaaattccaa
     2761 acgaacttgg agatagctgg ttctctccga aatagcttta gggctagcgt cgacattaga
     2821 gattcttgga ggtagagcac tgtttgggtg aggggtccat cccggattac caatctcaga
     2881 taaactccga atgccaatga attatggtcg gcagtcagac tgcgagtgct aagatccgta
     2941 gtcgaaaggg aaacagccca gaccaccagc taaggtccca aaataattgt taagtggaaa
     3001 aggatgtggg gttgcacaga caactaggat gttagcttag aagcagctat tcattcaaag
     3061 agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg ggctaaaaca
     3121 atttaccgaa gctgtggata cctttatagg tatggtagga gagcgttcta tgtgtgatga
     3181 aggtataccg tgaggagtgc tggaacgcat agaagtgaga atgccggtat gagtagcgaa
     3241 agacaggtga gaatcctgtc caccgtaaga ctaaggtttc caggggaagg ctcgtccgcc
     3301 ctgggttagt cgggacctaa ggagagaccg aaaggtgtat ccgatggaca acaggttgat
     3361 attcctgtac tagagtatgt agtgatggag ggacgcagta ggctaactaa agcagacgat
     3421 tggaagagtc tgtctaagca gtgaggtgtg aattgagtca aatgcttaat tctataacat
     3481 tgagctgtga tggggagcga agtttagtag cgaagttagt gacgtcacac tgccaagaaa
     3541 agcttctagc gtttaaacat actctacccg taccgcaaac cgacacaggt agtcgaggcg
     3601 agtagcctca ggtgagcgag agaactctcg ttaaggaact cggcaaaatg accccgtaac
     3661 ttcgggagaa ggggtgctga ctttaagtca gccgcagtga ataggcccaa gcaactgttt
     3721 atcaaaaaca cagctctctg ctaaatcgta agatgatgta tagggggtga cgcctgcccg
     3781 gtgctggaag gttaagagga gtgcttagcg taagcgaagg tatgaattga agccccagta
     3841 aacggcggcc gtaactataa cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg
     3901 acccgcacga aaggcgtaat gatttgggca ctgtctcaac gagagactcg gtgaaatttt
     3961 agtacctgtg aagatgcagg ttacccgcga caggacggaa agaccccatg gagctttact
     4021 gcagtttgat attgagtgtc tgtaccacat gtacaggata ggtaggagtc taagagatcg
     4081 ggacgccagt ttcgaaggag acgctgttgg gatactaccc ttgtgttatg gccactctaa
     4141 cccagatagg tgatccctat cggagacagt gtctgacggg cagtttgact ggggcggtcg
     4201 cctcctaaaa ggtaacggag gcgcccaaag gttccctcag aatggttgga aatcattcgc
     4261 agagtgtaaa ggtataaggg agcttgactg cgagagctac aactcgagca gggacgaaag
     4321 tcgggcttag tgatccggtg gttccgtatg gaagggccat cgctcaacgg ataaaagcta
     4381 ccctggggat aacaggctta tctcccccaa gagttcacat cgacggggag gtttggcacc
     4441 tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc caagggttgg gctgttcgcc
     4501 cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag acagttcggt ccctatccgt
     4561 cgcgggcgta ggaaatttga gaggatctgc tcctagtacg agaggaccag agtggactta
     4621 ccgctggtgt accagttgtc ttgccaaagg catcgctggg tagctatgta gggaagggat
     4681 aaacgctgaa agcatctaag tgtgaaaccc acctcaagat gagatttccc atgattatat
     4741 atcagtaaga gccctgagag atgatcaggt agataggtta gaagtggaag tgtggcgaca
     4801 catgtagcgg actaatacta atagctcgag gacttatcca aagtaactga gaat
//
LOCUS       DAVKAU010000082         4530 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVKAU010000082 DAVKAU010000000
VERSION     DAVKAU010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4530
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.082"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(311..862)
                     /locus_tag="VWX48_001970"
     CDS             complement(311..862)
                     /locus_tag="VWX48_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9172522.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(1212..2036)
                     /gene="nadE"
                     /locus_tag="VWX48_001971"
     CDS             complement(1212..2036)
                     /gene="nadE"
                     /locus_tag="VWX48_001971"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU9172523.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(2033..3493)
                     /locus_tag="VWX48_001972"
     CDS             complement(2033..3493)
                     /locus_tag="VWX48_001972"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU9172524.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRLVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(3609..4097)
                     /locus_tag="VWX48_001973"
     CDS             complement(3609..4097)
                     /locus_tag="VWX48_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172525.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(4087..4296)
                     /locus_tag="VWX48_001974"
     CDS             complement(4087..4296)
                     /locus_tag="VWX48_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9172526.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
BASE COUNT         1289 a         1054 c          839 g         1348 t
ORIGIN      
        1 cataaataaa attggttgaa tttaattccc taactcgata gaggattcta ttttaaattt
       61 aacaacagct aggattacac tataaaaagt acattaccac ctgttcggct ggagaatcta
      121 gtcgattagc tccctcttag ttacaagctt aaagcgattt tttaactaat actaaaccag
      181 attaaagaag gaactagaac atctgtcttg tactaatcaa tatgctattt taaaattgca
      241 aataaacttg gaatgctaat tattatattt acaataaata gttgacttcg atagaaacag
      301 aaaatagaat tcaacattct tccctactta taccataata aataagatcc gcaagatagc
      361 cttttctctc tacaccatta acaatggttt gtagatagga cattccagcc ttttccatga
      421 cacgacctga agctgggttg agactggcat aacgtgctct gaccttttga aaacctgctt
      481 gagtaaaaca aaagtccaag acagctttca aggcctctgt catcatacca tgtccccagt
      541 aagccttgcc tagcacatag ccgatttcac agcttaaatc agcctcgtct atcttaacga
      601 tgctgatatc tcctatcact tgctctgggt tttcttttag acaaatggcc catttgtaat
      661 agttgagatt agtataggaa gcaacccaat tgcgaatcga gtttcgagtg atttcgacat
      721 caggatgggg atcccaggta acataggtca gattctcagc ggatgaagcc caattttgaa
      781 acatggcttc tgcatcactc tccacaaatc ttcttaaaat caaacgttct gtctgtaata
      841 tttgcgtacc aatagatttc atgatgctac ctcacttcct tatttctatg ctcgtagtaa
      901 aaaggctcaa ctcagtaaca gctagaaaac gagtttgtct tctaatttct tgacgcagtc
      961 gctgcctggt ttgaaatgcg atctagcaag ctttttcaaa cctagtcatc gttgcagggg
     1021 taagacgatg aaatcgaact cttcgagtta ccgaatctgc ctcattttct tatttctaaa
     1081 ctcgaggttc aagatccccc ggaccttctc tcactttctt atttcaagat gagaggctga
     1141 aaacctccag tggaggtttt tcttgctttt taatttcagg gcaagaagct aaaaaggtcc
     1201 cccggacctt tttactccca aaagtcatca aatacggtga tgggtaagtg gcgtttgtgt
     1261 tggcctttgt gccaccagtt ttcaatggtc gcttgagctt ctgggctgat tgttttgcct
     1321 tctaggtagt cgtcaatctc tgcgtaggtg actccaagtg cgacttcgtc agctaggcct
     1381 ggtttatctt cttctaggtc tgccgttggg attttttcat aaagggctgg ctctgcgcca
     1441 agtttctgca agagctgttt tccttggcgt ttattgaggc ggtaaagagg gagaatatcc
     1501 gcaccgccgt caccaaactt ggtaaagaaa cctgtgatat tttctgcggc gtggtctgtt
     1561 ccaatgaccg ctccgctatg ggaaccagca agggcatact gagcaatcat acggcaacgt
     1621 gccttgatat tccccttgtt gaagtctgaa acaggactac ctgtcgcttc aactgcagct
     1681 gtcatggcat cagctgattc cttgatattc acaaccaagc tgacatctgg ctggatgaag
     1741 gctagggctt tttgagcatc tgcttcatca gcttgcactc cgtatggcag gcggacagcg
     1801 ataaatttgt agctatcgtc tcccgtttca gctcgcagtt cttccatagc taattgcgcc
     1861 aaacgtcctg ccaaggttga gtcttgtccc ccagaaatcc ctagtacaaa ggtttttagg
     1921 aagggatgtt ttttcagata tctttttaag aaatcaatag aacgacggat ttcttcctgg
     1981 gcatcaatca ctggtttgac acccagctct tggataatcg tttcttgcaa actcattctt
     2041 cttctccttc accaagggct tccttgcgca tcttatcaat caagtccatc ttatcttgcc
     2101 atacgtcacg cgccaaatcc actggatagt gctgcggatt gagcacacgc ttatactcat
     2161 cccacaactt gtcaaattcc ttacgggcat aatcctgaat gtcagtcaaa ctaggcaagt
     2221 tgtaaactaa tattccttct ttgaagatat ccaccaagag aggaacggca tcaaaattac
     2281 gaaccgtctt cttgatgtat gtataggtcg gatggaacat cttgatttct gtcatgtcgc
     2341 taatatccac accatcataa gtgatgtagt caccttctga cttgcctttt tcacgactgg
     2401 taatgcgcca cacctgcttc ttacctggcg tcgacacttt ttccgcatta ttagacagct
     2461 taatcgtatt gcgcatctgg ccgttttcat cttcgattgc aacaatcttg taaaccgccc
     2521 caagagccgg ctggtcatag gctgtaatca gcttggtacc cacaccccag acatcaatct
     2581 tggccttttg catcttgagg ttaaggatgg tattttcatc tagatcatta gaagcataaa
     2641 tcttagcctc tggaaatcca gcctcgtcca gttgctgacg gactttctta gaaatgtagg
     2701 caatatcccc agagtcaatc cgcacaccca taaagttaat ctgatcaccc agctcacgcg
     2761 ccacctgaat ggcagctggt acaccgatgc gaagggtatc ataggtatcc acaagaaaga
     2821 cacaattttt gtgggtcgca gcgtaagcct tgaaagcctc atagtcattg ccataaacct
     2881 gtaccaaggc atgggcatgg gttcccaaaa caggaatgtc aaagagctta cccgcacgca
     2941 cgttgctggt tccattggcg ccaccaatca ccgctgcgcg tgttccccag atggccgcat
     3001 ccatttcttg agcccgacgt gtcccaaact ccatcaaggg ttcatcttcg ataaccaaac
     3061 gaatacgagc tgccttcgtc gccaccaagg tctggtagtt gacgatgttc aaaagagccg
     3121 tttcgaccaa ctgacattgg gctagaggtc cttccacctg cacaatcggt tcattagcaa
     3181 aaaccaaatc cccttcttgg gcagaacgaa cggtcaactc caacttgaaa ttgcgaaggt
     3241 aatccaagaa cgccccatga taaccaagcg actccaaata ggctatatca ctatctgaaa
     3301 aacgcaagtc ttcaagatag ttcacaattc tttccaaacc tgcaaaaacc gcatagccgt
     3361 tcttaaaagg ctgttggcgg aaatacacct caaagaccgc cttcttattg taaatccctt
     3421 gatcaaagta aacctgcatc atgttgatct ggtacaagtc cgtgtgcaat gtcaaactat
     3481 catctggata catacttttc ctacttcctt agctagaaac ccatgaaaat tttcaagaac
     3541 tttcatgtat tccaataaat tagtactatt atatcacatt ttagctggat tgagaaaaga
     3601 gtaacaagct attctccact ctccaattca tccatatctt gttcaaattt tttctgagcc
     3661 cattcgccat agctcttaag accaagattg ccaataaaga cccacggaag gtaaatgaca
     3721 taagtaatga cccaagcaga caggtattta aaattcaaag gattgtgctg ataaatttct
     3781 atgttgaatt gataattctg caacatcaaa agagccgtaa tagccaaggt taggaaaaaa
     3841 caacccaaaa tcgtaaaatg aaaacgacta tagtaggtca ctcccagata acgggcacga
     3901 ttgaaaaagt aaaatgtccc tatgatgata acgattagca gcatattaga attaaaaagg
     3961 cttggtgcta atactgaaat gatataagat aggagcgaca aagcaatgca gatatagaaa
     4021 ctttcagagc ccgctttatt gaacagttgt tcttctcttt cgtctagtaa ttgataataa
     4081 taaaatctat ttttcatctt cttcctccca aaatagttgg tctagggttt tccctaaaca
     4141 tctgcaaata gactggcaga gcgagagact gggattgtat tttcccgcct ctatcaaacc
     4201 aatagtctgg cgtgtcaccc cgacagcctc tgccagttga ccttgtgtta aatcacgctc
     4261 tacccgagct aattttaatt ttaaattttt agccaccttc gtcctcctta tagttttaat
     4321 actcatctac tcttaaaaaa tccaaaacca acacaagcta tcagctattt attataaccc
     4381 cattaatttg cactccagta ttatcttcag ccgaaaatca gtattttagg ttgtttgaaa
     4441 taaacttcct agtttactct tttattttta tttagtatta gctttagtag gatcttttaa
     4501 acgagttttt attgcttata tttcttgttt
//
LOCUS       DAVKAU010000083         4256 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVKAU010000083 DAVKAU010000000
VERSION     DAVKAU010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.083"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            213..476
                     /locus_tag="VWX48_001975"
     CDS             213..476
                     /locus_tag="VWX48_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU9172527.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            482..2215
                     /gene="ptsP"
                     /locus_tag="VWX48_001976"
     CDS             482..2215
                     /gene="ptsP"
                     /locus_tag="VWX48_001976"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU9172528.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            2470..>4256
                     /locus_tag="VWX48_001977"
     CDS             2470..>4256
                     /locus_tag="VWX48_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9172529.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEQPSLQPTPEPSPSPQPAPSNPIDEK
                     LVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDL
                     PSSDREFYNKAYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILA
                     FLAPIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTP
                     HMTHSHWIKKDSLSEAERAAAQAYAKEKG"
BASE COUNT         1403 a          825 c          919 g         1109 t
ORIGIN      
        1 atagcaatga ttatcctata aattgttttt gaagaaacta tatcctgtgt tttgttatct
       61 aggatagaag attttcagca agttatctga aaggaaattg aaggaaaatc cagaaaatgc
      121 ttgaaaaaaa tcctagaaga tggtataata ctaaattgta agggttatca catataactc
      181 aaaaaaagaa agaacaaaag gagagtcaaa ctatggcttc taaagatttc cacgtagtgg
      241 cagaaacagg tattcacgca cgtccagcaa cattgttggt acaaactgct agcaaatttg
      301 cttcagatat cactcttgag tacaaaggta aatcagttaa ccttaaatca attatgggtg
      361 ttatgagtct tggtgttggt caaggtgctg acgtaactat ctcagctgaa ggtgcagatg
      421 cagatgacgc tatcgctgca atctcagaaa caatggaaaa agaaggattg gcataaggga
      481 aatgacagaa atgcttaaag gaatcgcagc atctgacggt gttgcagttg caaaagcata
      541 tctactcgtt cagccggatt tgtcatttga gactattaca gtcgaagata caaacgcaga
      601 agaagctcgc cttgatgccg ctctacaggc atcacaagac gagctttctg ttattcgcga
      661 gaaagcagta ggtacgctcg gtgaagaagc agctcaagtt tttgatgctc acttaatggt
      721 tcttgctgac ccagaaatga tcagccaaat caaggaaact atccgtgcga agaaagtgaa
      781 tgcagaagca ggtctgaaag aagttacaga tatgtttatc actatctttg aaggcatgga
      841 agacaaccca tacatgcaag aacgcgcagc ggatatccgc gacgtgacaa aacgtgtatt
      901 ggcaaacctt cttggtaaaa aattgccaaa cccagcttct atcaatgaag aagtgattgt
      961 gattgcgcat gacttgactc cttcagatac agctcaattg gacaaaaact ttgtaaaagc
     1021 ttttgtaacc aacattggtg gacgtacaag ccactcagct atcatggcac gtacacttga
     1081 aattgctgct gtattaggta caaacaacat cactgaaatc gttaaagacg gtgacatcct
     1141 tgctgttaac gggatcactg gagaagtgat tatcaaccca acagatgaac aagcggcaga
     1201 atttaaagca gctggtgaag cctatgcgaa acaaaaagct gaatgggcac ttttgaaaga
     1261 tgctcaaaca gtgactgctg acggtaaaca cttcgagttg gctgccaata ttggtactcc
     1321 aaaagacgtt gaaggtgtta acaacaacgg tgcagaagct gttggacttt accgtacaga
     1381 gttcttgtac atggattctc aagacttccc aactgaagat gagcagtatg aagcatacaa
     1441 ggctgttctt gaaggaatga acggtaaacc tgttgtcgtt cgtacaatgg atatcggtgg
     1501 agataaggaa cttccttact tcgatatgcc tcacgaaatg aacccattcc ttggattccg
     1561 tgctcttcgt atctctatct ctgagactgg agatgctatg ttccgcacac aaatccgtgc
     1621 tcttcttcgt gcgtctgttc acggtcaatt gcgtatcatg ttcccaatgg ttgcgctctt
     1681 gaaagaattc cgtgcagcga aagcagtctt tgatgaagaa aaagcaaacc ttcttgctga
     1741 aggtgttgca gttgcggata acattcaagt tggtatcatg atcgagattc ctgcagcggc
     1801 tatgcttgca gaccaatttg ctaaagaagt tgacttcttc tcaattggta caaatgactt
     1861 gatccaatat acaatggcag cagaccgtat gaacgaacaa gtttcatacc tttaccaacc
     1921 atacaaccca tcaatcctac gcttgattaa caatgtgatc aaagcagctc acgctgaagg
     1981 taaatgggct ggtatgtgtg gtgagatggc tggtgaccaa caagctgttc cacttcttgt
     2041 cggaatgggc ttggatgagt tctctatgtc agcaacatct gtacttcgta cacgcagctt
     2101 gatgaagaaa ctcgacacag ctaagatgga agagtacgca aaccgtgccc ttacagaatg
     2161 ctcaacaatg gaagaagttc ttgaacttca aaaagaatac gttaattttg attaatcgaa
     2221 aagtccctgc aactcagtta cagggacttt ttttgatatt ttaaaaagaa ttttcaagaa
     2281 aatctttctt ataaaaagtc caaccttgaa aaagtagtgg tcagaacaaa aaatacttaa
     2341 atggttcata aaattcttga caagttggag atttaggagt aaactattaa ccagttaagt
     2401 aatagagagg agtttctgca atttagaaat gaattgcaac tagaaatatc aaatagaaag
     2461 agagtttcga tgaaaattaa taagaaatac cttgttggtt ctgcggcagc tttgatttta
     2521 agtgtttgtt cttacgagtt gggactgtat caagctagaa cggttaagga aaataatcgt
     2581 gtttcctata tagatggaaa acaagcgacg caaaaaacgg agaatttgac tcctgatgag
     2641 gttagcaagc gtgaaggaat caatgctgag caaatcgtca tcaagataac agaccaaggc
     2701 tatgtcactt cacatggcga ccactatcat tattacaatg gtaaggttcc ttatgatgcg
     2761 attttcagtg aagaattact catgaaagat ccaaactata agctaaaaga tgaggatatt
     2821 gttaatgagg tcaagggtgg atatgttatc aaggtagatg gaaaatacta tgtttacctt
     2881 aaggatgctg cccacgcgga taacgtccgt acaaaagagg aaatcaatcg acaaaaacaa
     2941 gaacatagtc agcatcgtga aggagggact tcaacaaacg atggtgcggt agcctttgca
     3001 cgttcacagg gacgctacac cacagatgat gggtatatct tcaatgcatc tgatatcatt
     3061 gaggacactg gtgatgctta tatcgttcct catggagatc attaccatta cattcctaag
     3121 aatgagttat cagctagcga gttggctgct gcagaagcct tcctatctgg tcgggaaaat
     3181 ctgtcaaatt taagaaccta tcgccgacaa aatagcgata acactccaag aacaaactgg
     3241 gtaccttctg taagcaatcc aggaactaca aatactaaca caagcaacaa cagcaacact
     3301 aacagtcaag caagtcaaag taatgacatt gatagtctct tgaaacagct ctacaaactg
     3361 cctttgagtc aacgacatgt ggaatcggat ggccttattt tcgacccagc gcaaatcaca
     3421 agtcgaaccg ccagaggtgt agctgtccct catggtaacc attaccactt tatcccttat
     3481 gaacaaatgt ctgaattgga agaacgaatt gctcgtatta ttccccttcg ttatcgttca
     3541 aaccattggg taccagattc aagaccagaa caaccaagtc tacaaccgac tccagaacct
     3601 agtccaagtc ctcaaccagc tccaagcaat ccaattgatg agaaattggt caaagaagct
     3661 gttcgaaaag taggcgatgg ttatgtcttt gaggagaatg gagtttctcg ttatatccca
     3721 gccaaggatc tttcagcaga aacagcagca ggcattgata gcaaactggc caagcaggaa
     3781 agtttatctc ataagctagg agctaagaaa actgacctcc catctagtga tcgagaattt
     3841 tacaataagg cttatgactt actagcaaga attcaccaag atttacttga taataaaggt
     3901 cgacaagttg attttgaggc tttggataac ctgttggaac gactcaagga tgtctcaagt
     3961 gataaagtca agttagtgga tgatattctt gccttcttag ctccgattcg tcatccagaa
     4021 cgtttaggaa aaccaaatgc gcaaattacc tacactgatg atgagattca agtagccaag
     4081 ttggcaggca agtacacaac agaagacggt tatatctttg atcctcgtga tataaccagt
     4141 gatgaggggg atgcctatgt gactccacat atgacccata gccactggat taaaaaagat
     4201 agtttgtctg aagctgagag agcggcagcc caggcttatg ctaaagagaa aggttt
//
LOCUS       DAVKAU010000084         4177 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVKAU010000084 DAVKAU010000000
VERSION     DAVKAU010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.084"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..328
                     /locus_tag="VWX48_001978"
                     /pseudo
     CDS             1..328
                     /locus_tag="VWX48_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            256..708
                     /locus_tag="VWX48_001979"
     CDS             256..708
                     /locus_tag="VWX48_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172530.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1540..1899
                     /locus_tag="VWX48_001980"
     CDS             1540..1899
                     /locus_tag="VWX48_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172531.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            1909..2274
                     /gene="mobC"
                     /locus_tag="VWX48_001981"
                     /pseudo
     CDS             1909..2274
                     /gene="mobC"
                     /locus_tag="VWX48_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
     gene            2261..4111
                     /locus_tag="VWX48_001982"
     CDS             2261..4111
                     /locus_tag="VWX48_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU9172532.1"
                     /translation="MVVTKHFAIHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSHAEMVEIYNVNFSNNDKLYESRNDRQEKHQQNIHAHHLIQSFSPEDNLTPKEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKMAGAKIIEKRFSYRDYQEYRATSHKFELKQRLYFLMQQSKSFDDFLEKAEQLH
                     VHIDFSQKHSRFMMTDRAMTKPIRGRQLSKRDLYDEDFFRMHFAKQEIASRLEFLLNC
                     VNSLEGLLTKSKELNLTIDLKQKNVIFILEENGKQFSLSHKKISDEKLYDVNFFQDYF
                     KNKEVGVSEGIENLQAQYRAFQEERDKEKVSTEEIEEAFETFKEKRDAVHEFEVKLTE
                     HQIEKLVDEGIYIKVSFGINQSGLIFIPNYQLDIMEEDNHKKYKVYIRETSSYFVYNK
                     ENRDNNCFIKGRTLIRQLSNDSQKLPYRRPTLKSLQEKISEINLMIELSNTNKQYQEI
                     KDELVLEIAEIDMKLEETQEKIATLNKMAEVLINLKSEDEIGRKLARYDFSKLNLTES
                     TSLENVNEEIRVLQENLDYYLYEFEKRAIRLEIFVSTLNMEKDVFVIDKF"
BASE COUNT         1534 a          605 c          823 g         1215 t
ORIGIN      
        1 gcagcagata aattgcatat tgtatgtata tatgattatg aacaagaatc atgggttaat
       61 caatggttaa gtgaaaatat tataagtgag aaagatggaa gttatcaaca ttcactgact
      121 ataatgaagg atttcaataa tcaaaaaata gttaactata ttgctcattt caatagttat
      181 gacattttga aaaaaggttc tcacttatta ggtgcatata aacgaaaaat tttttctaaa
      241 gaaaatacac gatttttgga gtttaatatt aactcgaaag aatcttcgca acaacttgat
      301 attctctata aagaagttgg tgtattaagt ttgggacaaa aagttgtagc catgcttgat
      361 tttttattag catatagtga ctattctaaa gacttcagac cattgattat tgatcagcct
      421 gaagacaatc tagacaatcg ttatatttac aggcatttag ttcagcagtt tagagatgtg
      481 aaagctcaac gtcaaattat tttagcaaca cataatgcta caattgtaac aaattctatg
      541 acagatcaag ttgttattat ggagtcagat ggagttaacg gatggattga atcacaggga
      601 tatgttagtg aaaaatatat aaaaaatcat atcatcaatc aattagaggg aggaaaagat
      661 tccttcaagc ataaaatgtc tatatatgag acggctttat cagagtagag tcagaaaaag
      721 taggctagaa atttagccta cttttttctt tgtccgacag gcatagtgta catctgaggt
      781 ccaagtcctc tgtggatatt tgctgcagat gaaaccaata gcgactccta atcctgaata
      841 tcgtgaggta ggggggatag gaaggaatta gcgaaatcaa ggctctacaa acagaatcgt
      901 gacttgaagc catatatagc ggatgaggaa ctctaaaatc caaataggtg tcgtaaccta
      961 tatacgtgaa ttacgagagt aaactaggaa agatgtacgg cttattccgt gagcgtttag
     1021 gacgtagtac aacgaatcat gggagtcagc tgaacacata gtattgaaga aatttctgta
     1081 atggaaatgg agcgaagaag tgaacaatta aatgaatacc tctctaatta aatttgtcaa
     1141 ttctaattcc tggtatgaaa agacagtgac ctgaaaatgt aaatgatggg agctgatcat
     1201 aaatatagga cgatacatgc agtagtgtta gagattagtc cctacttgat ttgtgataac
     1261 ttccccaaat ttcttctgct atacttttct caacttttaa aaatccaact aagaatttta
     1321 cctgggtgtt tgggggcgga gccaccaagt tatcttatgg ttagctgtca aaactagaag
     1381 gttttgatag gctggcgata tgatttttgg gatattgtgt ccacaatatc tgagctcgca
     1441 aagaccgaac aaggagagac tgaggtcttt aggaatcgta ctgacaatgt gaggcagcct
     1501 tacactgtca gacaagttga atgttgaagg aatatcagaa tgggacaaga aattaagtta
     1561 atccgtaagc aatttagaat cacgagacaa gaagaaaaac agataaaaga aatgatgagg
     1621 gaacaaaaag tggatagttt ctcagaattt cttcgtcaaa atttattgaa aaagaattat
     1681 caggatagaa tttttgaaag ttggttctcc ctttggcagt ctcaaaagtt tgaacagatt
     1741 agtcgagatg tgtatgaagt tctggttgtc gcaagagaaa atcatcaagt gactcaagag
     1801 cacgtctcaa tcttattgac ttgcgttcaa gaattgattg cagaagtgaa tcaagtacag
     1861 ccactcagtc gtgagtttcg tgaaaaatat atgggttagg aggatgtaat ggtttatcgc
     1921 tatcgtacca atctcaaaaa agtatttcta actgatccag aattgaatta attaaatgat
     1981 cgtattacta agagtcactg tcaaaatttc tcagtctacg ccagaaaagt gttacttaat
     2041 cctaatatgg cttttgtcac aattaacacg gatacctatg aacagttagt atttgaattg
     2101 agacggattg gaaataatat taatcaaatt gcgcgcgcta tcaatcagag ccatctgatt
     2161 tctcaggacc aattacaaga attgagtaag ggaattagtg agttaattac tggagtagag
     2221 aaagattttc aagttgaagt gaatagactg aaggagtttt atggtagtca ctaaacattt
     2281 tgcgatacat ggtaaaaaat atcgtaggcg tttaattaag tatattctca accctgataa
     2341 aacggacaat ttgaaattgg tatctgattt tggcatgagc aattacttgg acttccctag
     2401 tcatgcagaa atggtagaga tatacaatgt caacttcagc aataatgaca agttgtacga
     2461 atccagaaac gaccgacagg aaaaacacca acaaaatatt catgctcatc accttattca
     2521 atcattttct cctgaggata atttaacacc aaaagaaatc aatcggattg gttatgagac
     2581 cattatggaa ttaacaggag gccgttttcg tttcatcgta gcgactcata cagacaaaga
     2641 tcatattcat aatcacatct taatcaacgc cattgactgt aattcagata aaaagttgat
     2701 atggaattat gccttggaac gaaaccttcg tatgatttca gaccgcattt ctaaaatggc
     2761 tggggcgaaa attattgaaa agcgtttctc ttaccgtgac tatcaagaat atagagcgac
     2821 tagccataag tttgaactaa agcaacgtct ttattttttg atgcagcagt caaaatcctt
     2881 tgatgatttt ttagaaaaag cagagcaatt acatgttcat attgatttta gtcagaagca
     2941 tagtcgattc atgatgacgg atcgggcaat gacaaaacca attcgaggac gtcaactcag
     3001 taaacgagat ttatatgatg aagatttttt tagaatgcat tttgccaagc aagagattgc
     3061 aagtcgttta gaatttttgt tgaactgtgt caattcttta gaagggttac taacaaaatc
     3121 aaaagaattg aatctaacca ttgacttaaa acaaaaaaat gtaatcttta tacttgaaga
     3181 aaatggaaag caattcagtc tgagtcataa aaaaataagt gatgagaaat tatatgatgt
     3241 caattttttt caagattatt ttaaaaataa ggaagtaggt gtttcagaag gaatagaaaa
     3301 tctacaggca cagtaccgtg cttttcaaga agaacgagat aaggagaagg tatctactga
     3361 agaaattgag gaagcctttg agacatttaa ggaaaaacga gatgccgttc atgaatttga
     3421 agtaaaactt acagaacacc aaattgagaa gttagttgat gaggggattt atatcaaagt
     3481 gtcctttggt ataaatcaga gtggtcttat tttcattcct aactatcaac tggatattat
     3541 ggaagaagac aatcataaaa aatataaagt ctacattcga gaaacgtctt cttactttgt
     3601 ctataataaa gaaaacaggg ataataattg tttcatcaag ggtaggacct taatcagaca
     3661 attgagcaac gatagccaaa aactccccta tagacgacca actttaaaaa gtcttcaaga
     3721 gaagatttct gaaattaatc ttatgattga actatctaac acgaacaaac aataccaaga
     3781 aatcaaagat gagcttgtgt tagaaattgc agagattgat atgaagctag aagaaaccca
     3841 agaaaaaatc gccaccttaa acaaaatggc ggaagtgctt atcaatctga agagtgaaga
     3901 tgagatcggt agaaaattag ccaggtatga cttttcaaaa ctgaacttaa cagaatcaac
     3961 ttcattagaa aatgtgaacg aagaaataag agtattgcaa gaaaacttag actattatct
     4021 ttatgagttt gagaaaagag caataagatt agaaattttt gtaagcacgt taaatatgga
     4081 aaaagatgtt ttcgtaattg acaaatttta gaggagggat aaagctagaa atgctggatt
     4141 atgcttgatt taaggaactg caatacatgg agcacac
//
LOCUS       DAVKAU010000085         4064 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVKAU010000085 DAVKAU010000000
VERSION     DAVKAU010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.085"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..272
                     /locus_tag="VWX48_001983"
     CDS             <1..272
                     /locus_tag="VWX48_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172533.1"
                     /translation="NHVLTLIFLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDV
                     IAYLFLGYLLVIQKAGYLFSVLLLFSNFSVPFIKEKEYELFKNSK"
     gene            1404..1643
                     /locus_tag="VWX48_001984"
     CDS             1404..1643
                     /locus_tag="VWX48_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172534.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            1628..1906
                     /locus_tag="VWX48_001985"
     CDS             1628..1906
                     /locus_tag="VWX48_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172535.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCSVASDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYVKVRKTDVKEMKWL"
     gene            2192..>4064
                     /gene="pspA"
                     /locus_tag="VWX48_001986"
     CDS             2192..>4064
                     /gene="pspA"
                     /locus_tag="VWX48_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEU9172536.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEDAPVANQSQAEK
                     DYDAAMKKSEAAKKEYETAKKKAEDAQKKYDEDQKKTEEKAELVRKADEKRQKANLAV
                     QEAYVKFQEAQREFNESPSRKKSDAKKKLDDASAHIEEVKLKQKEADANFNKEQAKVI
                     PEASDLAVTKQKAEEAKKEAEVAKEKYDKAVQEVEVEKNKILEQDAENEKKIDVLQNK
                     VADLEKGIAPYQNKVAELNKEIARLQSDLKDAEENNVEDYIKEGLEQAIADKKAELAT
                     TQQNIDKTQKDLEDAELELEKVLATLDPEGKTQDELDKEAAEDANIEALQNKVADLEN
                     KVAELDKEVTRLQSDLKDAEENNVEDYVKEGLDKALTDKKVELNNTQKALDTAQKALD
                     TALNELGPDGDEEETPAPAPKPEQPAEQPKPAPAPQPAPAPKPEKTDDQQAEEDYARR
                     SEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWLQ
                     NNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGW
                     LQYNDSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMAT
                     "
BASE COUNT         1501 a          617 c          788 g         1158 t
ORIGIN      
        1 ctaatcatgt actgactctt atctttttga taaaaatttg tgtagatacc acgataaaat
       61 ttttattcat cagattattt gacacaagta ctttaatgaa gaggagaata ttttttcttt
      121 tcgcattgga tgttatagct tacttatttt taggatatct tttagtgatt caaaaagcag
      181 gctatttgtt ttcggtttta cttctttttt ctaatttttc agttccattt atcaaagaaa
      241 aggaatacga attatttaaa aatagcaagt aatagaaata tggattaaat cttagaacgg
      301 cttaaaatca gatatgataa agggaaatag tcttatctag gtaactaagt gctacaaaca
      361 cagtcgagga tcacttgtta ggattacatt ttaatcatgc ttaataagaa tggagaattc
      421 ctatggggat tgtattactc tgaagtttcg aataccttag ttctcgtgat tttgagctat
      481 tctagcttta gaatccttca gaacgtaaaa ttttaagcag tcaaagactt agaatagccc
      541 gaaaacattt attttataac aattctaaga ttagaattgc tcatatatat gtatttgagc
      601 tgctcgatag ttaggacagc tctattctga gaaatctgac ctatcaatgc ttcagaatag
      661 tatttcgcaa atggttttta ttgaagaggt gattgtttta tgatagtcta aaataaaact
      721 gatttatgga gtaaatggag aatcgtcaca tgaaacattt ttttgcagga attggtgaga
      781 taaaacttgt tggctactta ttgtatatat gtgtaggact agcccctctt tttcatatat
      841 atgtcatagg ttcggaactg agttttgtga aaatagtgtt atctattttg ggagttatat
      901 ttgtaagtat gttaactatt gctcgaattt atcggacttt tctataaaga atagtttgga
      961 cttgaactgt atctaaaaac agaggttggt cgattatcag cctctttctt gtcgttgaaa
     1021 agagtgagat atattgactt ttgaaaaaaa tgtcataatt gagttgggat aaacctaaaa
     1081 gtaatatagt agattgaatc tggaatagtc cgttatgact gttaaaatat ttctagaaat
     1141 taatttgact ttcctaatcg atttgttcac atcttgtttc aatctactat actttctcgt
     1201 taaaccgttc ggcaattcat ggtgacatgg acacatagta gtaagcacac tatgtggctt
     1261 ggcagagcta aaaactgttc ccttgcgata agcctaataa gcacaacata gggagttaga
     1321 gaagccgact ctaatcaacc actttgggca atagtgagaa ctgccccgtg cttttttatt
     1381 ttgagaaaat atggagtttg tcgttgaaat tacttgattg tattttggac tatcaagaaa
     1441 gattcaatgg aaaaacatgt caagtatcaa cgaattataa gtatttagag attttcaaag
     1501 tgaatttttg tttgactgat ttacatcatt tatttgactt atacaaaatc acacgagatt
     1561 atgctagtca aacaaaacct gctattcaag ctggtgtttt tattttagaa gattttagaa
     1621 atatcctatg tacaatgatg taatcgaaag gatatcttta tatgagttta tcggtgatat
     1681 tttctattct aaaataataa gttgttgcag cgtagctagc gatttatcta aaaatactat
     1741 gaaattggac gtcatatttt ttgaggataa aaataaaaga tccgcagttt taggtttacg
     1801 aagagacaaa agcggagtat ttaaaccagt tactctacat tttacaagcg ctaagaaata
     1861 tgttaaagtt cgtaaaacag atgtgaaaga aatgaaatgg ctataaagat tgtccgcagg
     1921 cttaagcttg cgttttttgt tgtttaacga aattaaaaaa caagctctct catcggaaat
     1981 gtttttatag gaatgaagga agatgatgct atgtttaaaa agagaatcga aaagggcaaa
     2041 agtagtgtct ttatcttttt ggagtagaag cttatgatat agaaatttgt aataaaaatg
     2101 taatataaaa catttgacaa atatttacgg ggggagtata cttaatataa gtatagtcta
     2161 aaaatgacta tcagaaaaga ggtaaattta gatgaataag aaaaaaatga ttttaacaag
     2221 tctagccagc gtcgctatct taggggctgg ttttgttgcg tctcagccta cttttgtaag
     2281 agcagaagac gctcccgtag ctaaccagtc tcaagctgag aaagactacg atgcagcaat
     2341 gaaaaaatct gaagctgcta agaaagaata cgaaacggct aaaaagaaag cagaagacgc
     2401 tcagaagaaa tatgatgagg atcagaagaa aactgaggag aaagcagagc ttgttcgaaa
     2461 agcggatgaa aaacgtcaaa aagcgaattt ggcagttcaa gaagcatatg taaaattcca
     2521 agaagcacaa agagaattta acgaaagtcc aagcagaaaa aaatctgatg ctaaaaagaa
     2581 attagatgat gcatcagctc atattgaaga ggtaaaatta aaacaaaaag aggcggatgc
     2641 gaattttaat aaggaacaag caaaagtaat tcccgaagca agtgacttag ctgttactaa
     2701 acaaaaagcg gaagaagcta aaaaagaagc agaagtagct aaggaaaaat atgataaggc
     2761 agttcaagag gtagaagtag agaaaaataa aatacttgaa caagatgctg aaaacgaaaa
     2821 gaaaattgac gtacttcaaa acaaagtcgc tgatttagaa aaaggaattg ctccttatca
     2881 aaacaaagtc gctgaattaa ataaagaaat tgctagactt caaagcgatt taaaagatgc
     2941 tgaagaaaat aatgtagaag actatattaa agaaggttta gagcaagcta tcgctgataa
     3001 aaaagctgaa ttagctacaa ctcaacaaaa catagataaa actcaaaaag atttagagga
     3061 tgctgaatta gaacttgaaa aagtattagc tacattagac cctgaaggta aaactcaaga
     3121 tgaattagat aaagaagctg cagaagatgc taatattgaa gctcttcaaa acaaagttgc
     3181 tgatctagaa aacaaggttg ctgaattaga taaagaagtt actagacttc aaagcgattt
     3241 aaaagatgct gaagaaaaca atgtagaaga ctacgttaaa gaaggcttag ataaagctct
     3301 tactgataaa aaagttgaat taaataatac tcaaaaagca ttagatactg ctcaaaaagc
     3361 attagatact gctcttaatg aattaggtcc tgacggtgat gaagaagaaa ctccagctcc
     3421 agcaccaaaa ccagagcaac cagctgaaca accaaaacca gcgccggctc ctcaaccagc
     3481 tccagcacca aaaccagaaa aaacagatga tcaacaagct gaagaagact atgctcgtag
     3541 atcagaagaa gaatataacc gcttgcccca acagcaaccg ccaaaagcag aaaaaccagc
     3601 tccagcacca aaaccagagc aaccagttcc tgcaccaaaa acaggttgga aacaagaaaa
     3661 cggtatgtgg tacttctaca atactgatgg ttcaatggct acaggttggc tccaaaacaa
     3721 cggttcatgg tattacctca acagcaatgg cgctatggct acaggttggc tccaatacaa
     3781 tggttcatgg tattacctaa acgctaacgg cgctatggct acaggttggg ctaaagtcaa
     3841 cggttcatgg tactacctca acgctaatgg tgctatggct acaggatggc tccaatacaa
     3901 cgattcatgg tattacctaa acgctaacgg cgctatggcg acaggatggc tccaatacaa
     3961 cggttcatgg tactacctca acgctaacgg tgctatggct acaggttggg ctaaagtcaa
     4021 cggttcatgg tactacctca acgctaacgg ttcaatggca acag
//
LOCUS       DAVKAU010000086         3589 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVKAU010000086 DAVKAU010000000
VERSION     DAVKAU010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.086"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(29..1021)
                     /locus_tag="VWX48_001987"
     CDS             complement(29..1021)
                     /locus_tag="VWX48_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9172537.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1181..2935
                     /locus_tag="VWX48_001988"
     CDS             1181..2935
                     /locus_tag="VWX48_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172538.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            2919..>3589
                     /locus_tag="VWX48_001989"
     CDS             2919..>3589
                     /locus_tag="VWX48_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172539.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     EDLYK"
BASE COUNT         1261 a          509 c          592 g         1227 t
ORIGIN      
        1 ataaaaacat ggcttgtaaa aaattacttt aatcacaata atcgcattta aaattgtgat
       61 gtttgcaagc taaattacgg acttcacttg gaagttttcc cttgtatctt ttataataga
      121 tagaaaattt gctggcagat gaatatccaa cagattctgc tatctctttt ataggtagtt
      181 cagtgtttaa aagaagagtt tcagctacat tcattctttt tctttgagtg tactctgtaa
      241 tgctttgaca atatttttcc ttaaataaat tttttaattt agtaccactc attttagata
      301 ttttttcaag cgtgccttga tttacattcg ttgcaaaatg atcatctaag aatcttgcta
      361 catcttcaag tgctttatca tcatcaattt caattttata tttttttcta tttaagtatg
      421 tgtcaattac tatacttatc cattcatttg cctttgcttt aaagaaaaaa tcagcggcag
      481 gagcgtccat cttacaattt aatatttcca ttgccactct ttctaaggcc tttgtaagta
      541 ttatttgatt cggttgaagc aaggttgaat aaaaagattc tggattaatg ttaatagatg
      601 ctaaatgttt ttctattagc tcttttttaa aaccaatgga aacagcaaga taacaacaat
      661 tctcgtgtaa taaaaaaaca aaatcatctt ttatattatc aaaatcaaaa gtacataaag
      721 agtttgcggt aatagtttga tacggattaa acttttctcc gtttgcactg acaatataac
      781 ttgaataaat tgaaacatag tctgacatac tataagtgct attttgaact acttcctctt
      841 tgatataaaa atcatgtata tcgataatga agctgcctcc ttcataaaac caatataggc
      901 cttctgcata agttgaattc tcttttttcc aacaaaatgt atgacctgca cttgaatact
      961 tctcattgtt tttacattca tctactttca tataatcttt tacaaaatca taatatgaca
     1021 taacacacta tcccttttag acaatattcc aattagcctt attaattcaa aactattgta
     1081 ttagtaatta taacagatgt ataatagaaa agcaatgata gatattatca attaagcgaa
     1141 tttatatcta aaagggatat taaagaaagg agatatgctt atgaagattt acaaaaaact
     1201 atttgcttat gtccaagata agaaatatct tggggttttg gccataattt tttctgctat
     1261 atctgctgca cttacagtat atggatatta tttaatctac aaatttctag ataagttaat
     1321 aattaattca aacttatccg gtgcagagag tatagcatta aaatctgtta ttacactaac
     1381 aagtggagcg atattttatt ttgtctcagg aatgttttca catatcttgg gatttaggct
     1441 tgaaacaaat ttaagaaaaa ggggaatcga tggtctggaa aaagcaagtt ttaggttctt
     1501 tgacttaaat ccatctggtc aaataagaaa gatcatagat gataatgcag cacaaactca
     1561 tcaggtggta gctcacatga ttccagatag ctctcaggca atagtcacac ctatacttgt
     1621 ccttgtacta ggctttatag taagtataag agttggcata attttgcttg ctcttactat
     1681 aattggtggc ttaattttag gggcaatgat gggcgagcaa gaatttatga agatatacca
     1741 agaatcccta tctaaactaa gtgctgaaac tgttgagtac gtgagaggaa tgcaagttgt
     1801 aaaaatattt aaagcaaatg tagagtcatt taaaagcttt tacaaggcta taaaagatta
     1861 ctcaaagtat gcttatgatt attccctatc ttgtaaaagg ccttatgttt tgtatcaatg
     1921 gttatttttt ggactgattg caattttaat tattcctata gtttatttta tgactagctt
     1981 agctagcgca aaggtgattt tacttgagct tatcatgatt ttatttttat caggagttct
     2041 ctttgtttca ttcatgagaa tgatgtggta ctccatgtat atttctcaag gaaattatgc
     2101 agtagatact ttagaggcgc tttacgaaga tatgcaaaaa gacaaattag tgcatggtaa
     2161 tgtcaataat tttaaaaact ataatataga atttgagaat gttagctttg cttataatga
     2221 taaagctgtc attgaaaatt tatcctttaa tttagaagaa ggaaagtcct acgcacttgt
     2281 cggttcatct ggatcaggca aatcaacagt agcaaaactt atatcaggtt tttacaatgt
     2341 taatgaagga agcataaaga taggcgggat agcaataagt gaatattctg acgaagcctt
     2401 aattaaagcc atttcctttg tttttcaaga ttcaaaatta ttcaagaaga gcatttatga
     2461 taatgtagct ttagctaata aagatgcgac gaaagatgac gttatgagag ccttaaaatt
     2521 agcaggatgc gatttaatat tagacaaatt cccagaaaga gaaaatacaa tcataggctc
     2581 aaaaggtgtt tatttatccg gtggagaaaa acaaagaatt gcaattgcta gagcaatttt
     2641 aaaggattcc aaaattatta ttatggatga agcatcagca tctattgacc cagataatga
     2701 gtttgaattg caaaaagctt ttaaaaatct tatgaaggat aaaacagtta tcatgattgc
     2761 acacaggcta tctacaatta aagaccttga tgaaattatt gtcatggata gtggaaaaat
     2821 tatagaaaga gggtctgaca aagaattaat gtcaaaagat acaaggtata agagcctgca
     2881 agagatgttt aacagtgcga atgaatggag ggtttcaaat gaaagagttt tataaaaaaa
     2941 gatttgctct tacagatgga ggagcaagaa atttaagtaa agcaacactg gcttcatttt
     3001 tcgtttattg tataaacatg cttcctgcca tattacttat gatttttgct caggaagttt
     3061 tggaaaatat gggcaaaagc aatggctttt atatagtatt ctcagttttg actttgatag
     3121 caatgtatat tttgctttct atcgaatacg ataaattata taacacaacc tatcaagaaa
     3181 gtgcagattt aagaataagg acagcggaga atttatcaaa attacctcta tcttactttt
     3241 ctaaacatga catttccgac atttcacaaa caatcatggc tgatattgaa ggcatagagc
     3301 atgcaatgag ccactcaata ccaaaggtgg gcggcatggt actgtttttc ccattaatat
     3361 ctgtaatgat gctagcgggc aatgtcaaga tgggtttagc tgtaattatt ccatctattt
     3421 taagctttat atttatacct ttatctaaaa aatatcaggt taatggacag aatagatatt
     3481 atgatgtctt aagaaaaaac tcagaaagct ttcaagaaaa tatcgaaatg caaatggaga
     3541 ttaaagcata taatttatcg aaggatatta aagaagactt atataaaaa
//
LOCUS       DAVKAU010000087         3363 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVKAU010000087 DAVKAU010000000
VERSION     DAVKAU010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.087"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..708)
                     /locus_tag="VWX48_001990"
     CDS             complement(<1..708)
                     /locus_tag="VWX48_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9172540.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALPPLSEQQRI"
     gene            complement(708..2171)
                     /locus_tag="VWX48_001991"
     CDS             complement(708..2171)
                     /locus_tag="VWX48_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9172541.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILDPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            complement(2184..>3363)
                     /locus_tag="VWX48_001992"
     CDS             complement(2184..>3363)
                     /locus_tag="VWX48_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HEU9172542.1"
                     /translation="NGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFD
                     KTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNF
                     PAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDF
                     RNVTNLFADPDFDGDPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNST
                     VQVLDENGKLITESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLD
                     AIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEIL
                     LNKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA
                     "
BASE COUNT         1005 a          662 c          502 g         1194 t
ORIGIN      
        1 tattcgttgt tgttcggata gtggggggag agcaattaat aatagattaa aattataatc
       61 attgattgca ggataacttg ttccagtaga tttattatta acacgattga taaaattatc
      121 tgataataaa taatatttca aatatgtttc gttaagtaaa gtatccaaaa caataaatgc
      181 tgtactagct atcaaatact ctttaagttc tctaactaca gcaatatttt ttagatatgg
      241 tctaactgtt gaaaataaga cactattctg cgaaactaat tttctagcac gggaaggcgc
      301 ttgttcaggt gaaagatatt gtagattttt gtagttgatt atgttctttt ttctatcaat
      361 actagacgta tctatatacc taaaggattt ctctggctta ttttgcccaa aattccaata
      421 aattgatttt atcctcaccc actcccaagt atcaggaata tcataaggaa catcaatttc
      481 ttgagtgctt ccatcagcaa acttcccata atgtttccca tcatcaccac gaaatatctc
      541 agtttccttt ttatctcgtt tgatttttcc ttcactgata agtttttctt tttcagcttt
      601 aattctcttt aataattcac ttgcaggttc gtcattggga ttttgcggca ctaatttccc
      661 ttccatcgct ctttggagaa tacttgcttt aagttgttct ggtgtcatta tttgtcctcc
      721 aacaactgca aaatatcagc taatacatta tcaatcttat gatttaaagt tgctctttcc
      781 gcttgataat tctgaatcaa ctcaaaggga tctaagattt cctcttcctc ttttggaaag
      841 ccacactggt ctaaattata attcaactca gccaattcac taggtgtaaa tgatttagat
      901 ttgtagaact taccttccag aatctcttca cgattttccc accagtcacg aacaggattg
      961 aagtgttctg acttcatcgg cttagttttc gagaaatttt tataaccatc tggcatatct
     1021 aaacgataaa accaagtttc ttctgttttc tttgttttat caaagaaaag aatgttcgta
     1081 tggattcctg tatacggtgc aaagacacta tgaggcaacc taataatcgt atgcaagttg
     1141 aactcatcta ccagtttttg tttcaagcga gtttttacac cttcaccaaa tagaaaacca
     1201 tcaggtaaaa taactccaac acgaccattt tctttcaaac gatacataat gacagccata
     1261 aataaatcag ctgtttcaga actccgtaat tctgctggaa agttattttt tattgtttct
     1321 aattctgacc ctccaaaagg tggattcatc ataataatgt caaatttttc atcatccgta
     1381 tattcacgaa catttttctc caaagtattt ccatgaacaa ttttagggtc atcaatttcg
     1441 tgaagaaaca gatttgtaac tgctaaaaga tgaggaaatg ctttcttttc aataccaaaa
     1501 acagctgtat tatatttttt ggtatcttca ctagttttac gttgactact taaacggttc
     1561 agagtcgaag tcaagaagcc tcctgttccg caagcaaggt ctgccattga ttctccaagt
     1621 tttgggttaa gaacttcggc aataaaatca gtcgctgcac gtggcgtata aaattctcct
     1681 gagttcccag cattttgaat atctttaaga attttttcgt aaatatcatt aaacgaatga
     1741 cgatcttcag ggctattgaa atcaacttca tcaataacat tgatgacttg gcgtaacaag
     1801 acgccatttt tcatatagtt gttcgcatct tcaaaagctg atttaacaat cgtttttcga
     1861 ataggcatat ttgaagttat ttcaagctct ttcaactctt tgaataactt gttattgaca
     1921 aaatcaagta attcatcgcc tgtcaatacc cgttccccat tttgagcatg agcccaattt
     1981 cgccatttta attcctctgg gataattgac tcatactcgt cttcttctaa ttcccaaacc
     2041 atttcacggc tatcataaat ttttaagaat aataaccaag acatttgctc aatacgttga
     2101 gcatcaccat taacaccagc atcgtttcga gtgatatctt gaattctttt tacaaatgat
     2161 gtaattgaca tactttcctt tcattaagct actgtaaata gctcttgctc caattcttta
     2221 attgcttgta aatatcgttt tttatctcca aaataagtat tgatgatttt gaaggttcca
     2281 ccatatatct gaaattctgg aagttttaat gtttcaatgc tttcgagttc tccaatacct
     2341 ttatccatgt atttgttcag taaaatttcc aaaacagcac gcgcttcctc actatattta
     2401 tataaatatc cgctttgttt gagtttattg atacgttccg ttttggttaa ttctttttga
     2461 ccataggcaa gttttaggag taaatcaaaa tcatcgattt cttgttctga tattccctcc
     2521 gactctcgaa tagcatctag ataaactcct tttttataaa gttcgtctaa gataagcttc
     2581 tttttatccg ccgtatgcca aactgtgata aaatcgttca aagtggcgta gctacctaag
     2641 atattcttcc gagtgtagtc ggtcaggctt tcggtaatca gtttcccgtt ttcatctaat
     2701 acttgaacag tagaattaag aatggtaacc tgcttgtctg taacgatata tttttctact
     2761 gggtcacctt cctcatctac gaaaccgggc gtagaaccac tgactgtttt cgcacctgtt
     2821 tccagcacct tcacaggatc accatcaaaa tcagggtcag caaacaaatt ggtaacattt
     2881 cgaaaatcaa taatcgtaaa aaattctttc cccttttgag gataaagacg tgtgccacga
     2941 ccaataattt gtttaaattc agtcatggat tggatattag agtctaaaac aatcaaacga
     3001 catgttttag cattaactcc tgtcgttaat aatttagacg ttgttacaat agcgggaaaa
     3061 ttagaattga catccataaa gttatccagt tgagcttttc cttcagcgtt gtcaccagtt
     3121 acttgcatga cataacgata gtcttcttgg actaagtcta gattctcttt tacaagtgca
     3181 gcacgcattc gctcggcatg gtcaatatca acacaaaaaa caattgtttt atcaaatcgt
     3241 gcattgcttt gcttcatata atcagaaaca aacttggcaa ctctttgcgt tctatcatca
     3301 atgacaatgg ttttatcaaa atctttcctg ccgtagtacc tatcttctat taattgtccg
     3361 tta
//
LOCUS       DAVKAU010000088         3223 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVKAU010000088 DAVKAU010000000
VERSION     DAVKAU010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.088"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(213..746)
                     /locus_tag="VWX48_001993"
     CDS             complement(213..746)
                     /locus_tag="VWX48_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU9172543.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(835..1611)
                     /gene="recX"
                     /locus_tag="VWX48_001994"
     CDS             complement(835..1611)
                     /gene="recX"
                     /locus_tag="VWX48_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU9172544.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKLISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKKISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1649..3004
                     /gene="rlmD"
                     /locus_tag="VWX48_001995"
     CDS             1649..3004
                     /gene="rlmD"
                     /locus_tag="VWX48_001995"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9172545.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            3066..3137
                     /locus_tag="VWX48_001996"
     tRNA            3066..3137
                     /locus_tag="VWX48_001996"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3099..3101,aa:Glu,seq:ttc)
BASE COUNT         1034 a          565 c          598 g         1026 t
ORIGIN      
        1 ataagtttgt tgtaaactta caaggaataa agacattaaa aaataacagt atatctattt
       61 gttttatata ttttacgaat tctgcataaa tttctttcta gtaatgtgtt gtaactctgc
      121 tataatggat ttattccttt ttgtgtttac acaatttatt ttatactacc aaaaaaacaa
      181 ggtcaggatt ttgttcctga cctttgacaa ctttaccgat tctttagttc tacatagcgc
      241 ttgtaccaaa tgtttacata ggcttctgag aaaggaccac gtccattgtt aatccaatca
      301 acaagaattt tgacatgttc ttttaaaata tagtccaagt catcagaata attcattttg
      361 cgtttgtgac gctcgtactc ttcaacgtcc aagagacgtt tttccccatc tgtaaaaatt
      421 ttaacatcca aatcgtaatc aatatacttc agtgcttctt catccagata gtaggggcta
      481 gccatattgc aatagtaaga agttccatta tcacgaatca tggcaatgat attaaaccaa
      541 tatttcttgt gaaagtaaac aatagccggt tctcgagtga cccaacgacg accatcactt
      601 tcggtaacaa gtgtatgatc gttgacacca ataatggcgt tttctgttgt ttttagtacc
      661 atggtgtccc gccaagttcg gtggagactc ccatcatgct tataactttg aattgtaata
      721 aagtcgcctt cttttggaag cttcataact aaccaacttt ctacaattta taagtttatc
      781 atttactatt gtaccataaa attacctaaa atctgtgaat ttcacttgga aatattaaag
      841 atattctcta agagcgcttg ctatatccga aaaatcgtag ccctttcgtg ctaaaacttg
      901 agttaaacgc tgcttcagtt cgtatccttc atactttcga gcatacttag tatattgctt
      961 atcaagttcc ttgaagatga gttcttgagt cgtttcttgg tcaacttggc tatctaagtc
     1021 gtcaaaggca attttagcat cagaataaga gaagcccttg ttagtcaagt tctggataat
     1081 cttatcttgc agggcacgag ctggaagttt tccctcatat tttttcaata gtttattagc
     1141 tacacgttga gcaacttcag aaaaatcaaa ttctttcaag ttctcttcta tagtagattt
     1201 tgaaatcttt ttttgagcta gtttctgagt cagcacataa ggacccttgt ctcctgaaag
     1261 ttgattggta ttgatgatag cataagcgta ctgaccatca ttaatccact tatcttcttt
     1321 aagattagca ataacttgag aaacgatgtt tttatcaata tcgtattttt tcagatattc
     1381 tctgacttct ttttcagtgc gtgctttaaa ggataagtgg tagagggcca gattcttacc
     1441 ataagaaaat tgagcaaagt cttgaatctc tttcaattcc tcttcgctta tcagcttatc
     1501 tctcgataac ataaaacgaa caattgtatc ttcggtgata tagcatttgt cgccattatc
     1561 aagctccatc agatagagtc tttttttctt ttcaagtttt gtgattttca tagctctatt
     1621 ataactcaaa atgtgataag ataggggtat gaatctgaaa gtgaaacaaa aaataccatt
     1681 aaaaatcaag cgcatgggaa ttaacggtga gggaatcggc ttttaccaaa aaacattagt
     1741 ctttgtacca ggagctctca aaggcgaaga tatctattgt cagattactt ctattagacg
     1801 caactttgtt gaagcaaaat tactgaaggt caacaagaag tctaaatttc gaattgtgcc
     1861 atcttgtact atttataatg aatgcggagg ctgccaaatc atgcacctgc attatgataa
     1921 gcagctggag ttcaagacgg acttacttca tcaagcgctg aaaaaatttg ctcctgcagg
     1981 atatgaaaat tatgaaattc gtccaactat tggaatgcag gaaccaaaat attacagagc
     2041 taagttacaa tttcagactc gaaaatttaa aaatcaggtc aaggcgggct tatatgcaca
     2101 aaactctcac tatttagtag agttgaaaga ctgcctggta caagataagg aaacccaagt
     2161 gattgctaat cgcttagcag aattacttac ttatcaccag attccaatca cggatgagag
     2221 aaaagttcta ggtgtccgta ctattatggt ccgacgcgcg agaaagaccg gacaggttca
     2281 gattattatt gttacaaacc gccagcttaa tttaactcaa ttggtaaaag agttggttaa
     2341 agatttccca gaagttgtga cagtagctgt taatacaaat acagctaaaa ccagtgagat
     2401 atatggtgaa aagacagaga ttatctgggg gcaagagagt attcaagaag gtgtactcaa
     2461 ttatgaattt tcactatccc ctcgagcttt ttatcaacta aatcctgagc aaacagaagt
     2521 cctctatagc gaagcagtaa aagcgctgga tgttgataaa gaagaccatt tgattgacgc
     2581 ttattgtgga gttggaacga ttggatttgc ctttgcaaag aaagtaaaaa cactcagagg
     2641 tatggatatt attccagaag ctattgaaga tgccaagcga aatgctaaaa gaatgggatt
     2701 tgacaatact cattatgaag ctggaacggc agaagagatt attcctcgtt ggtacaagga
     2761 aggctaccga gcagatgctt tgattgttga cccaccacgt acaggtctgg atgataagtt
     2821 attagatact attcttactt atgtaccaga aaaaatggtt tatatttctt gtaatgtttc
     2881 gaccttggct cgtgatttgg tacgcttagt agaagtctat gatcttcatt atatccagtc
     2941 ggtcgatatg ttcccacata cagctcgaac tgaagctgtt gtaaaattaa taaaaaaagt
     3001 ttaaaaaagg tgttgacaaa gtttgaaaag actgtataat agtaagagtt gaaaataaca
     3061 actcaggtcc gttggtcaag gggttaagac accgcctttt cacggcggta acacgggttc
     3121 gaatcccgta cggactatgg tatgttgcgg ttggaacact tgatgaaaaa aagtttaaaa
     3181 aagcttaaaa atcttcaaaa aaagtgttga caagtgaaag tgg
//
LOCUS       DAVKAU010000089         2954 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVKAU010000089 DAVKAU010000000
VERSION     DAVKAU010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2954
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.089"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..978
                     /locus_tag="VWX48_001997"
     CDS             <1..978
                     /locus_tag="VWX48_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9172546.1"
                     /translation="FSACSSNSVKNEENTSKEHAPDKIVLDHAFGQTILDKKPERVAT
                     IAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKELNGKANLFDDLDGLNF
                     EAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQTLWRDMIKIDSKALGME
                     KEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAADTSKFWIYTSKDPRANY
                     LTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITYGDDKTLEALQKDPLLG
                     KINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLGNACKNAK"
     gene            968..1975
                     /locus_tag="VWX48_001998"
     CDS             968..1975
                     /locus_tag="VWX48_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9172547.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            1975..>2954
                     /locus_tag="VWX48_001999"
     CDS             1975..>2954
                     /locus_tag="VWX48_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9172548.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLL"
BASE COUNT         1002 a          429 c          514 g         1009 t
ORIGIN      
        1 tttagcgctt gttcttctaa ttctgttaaa aatgaagaaa atacttctaa agagcatgcg
       61 cctgataaaa tagttttaga tcatgctttc ggtcaaacta tattagataa aaaacctgaa
      121 agagttgcaa ctattgcttg gggaaatcat gatgtagcat tagctttagg aatagttcct
      181 gttggatttt caaaagcaaa ttacggtgta agtgctgata aaggagtttt accatggaca
      241 gaagaaaaaa tcaaagaact aaatggtaaa gctaacctat ttgacgattt ggatggactt
      301 aactttgaag caatatcaaa ttctaaacca gatgttatct tagcaggtta ttctggtata
      361 actaaagaag attatgacac tctatcaaaa attgctcctg tagcagcata caaatctaaa
      421 ccttggcaaa ctttatggag agatatgatt aaaattgatt caaaagcctt aggtatggaa
      481 aaagaaggtg atgagttaat caaaaatact gaagctcgta tatccaaaga attagaaaaa
      541 catccagaaa tcaaaggaaa aatcaaagga aaaaaagtat tatttactat gattaatgct
      601 gcagatacat caaaattctg gatttatact agcaaagatc caagagcaaa ttatttaaca
      661 gatttaggtc tagttttccc tgaatcatta aaagaatttg agagtgaaga tagttttgca
      721 aaggaaattt ctgcagaaga agcaaataag ataaatgatg ctgatgtaat cataacttat
      781 ggtgatgata aaactcttga agctttacaa aaagatcctc ttttaggtaa aataaatgca
      841 attaaaaatg gtgccgttgc tgtaattcca gataatacac cgttagcagc ctcatgcact
      901 ccaacaccac tttcaataaa ctatactatt gaagaatacc taaatctttt aggaaatgca
      961 tgcaaaaatg cgaaataaaa aacaaataaa cctaggcata atttttgtaa tctgcctagg
     1021 tcttcttatt acaatatttt tgtcattaaa gcttggaaca aaagaaatta atatcagaga
     1081 ttttttagca gcttttggaa tgggcaatac aaatgatgat tttattaaat caattatata
     1141 taaaagaata cctagaacta tttttgcaat tttagcaggt tctagtcttg ccataagcgg
     1201 tgtattgatg caatcagtta ctagaaaccc aatagctgat ccaggtatac tcggtataaa
     1261 cacaggagca agtcttagtg tagtaattgg tctttctttt ttaggaattt catcaagcat
     1321 aagccatata agttttgcaa tcattggtgg cttagtaagt gcaatttttg tatacgcgat
     1381 tgctgtaagc ggaaaagcag gccttacccc tataaaactt gccttatcag gaacttgtgt
     1441 tagtatggct ttaagcagtt ttgtaagttt tttaatttta ccgaataata acgtcttaga
     1501 caaatttaga ttttggcaaa taggtagcct tggagcagct acattatctt ctatatctac
     1561 actactacct tttataattt taggtcactt gatagctata tttatttcat cagatttaaa
     1621 cgctttagct atgggtgatg aaatggctgt tggtcttgga gttaatgtta ataggataag
     1681 atcacttgca ataattgcaa gtgtgctttt atgttcaagt attactgcaa ttggtggacc
     1741 tattggcttc gtaggtctta tagttcctca cttttgtggc ttatttataa gcaaagatat
     1801 acgcacaatg accatttctt catcttttat aggtgcagag ctcttgctta tatgtgatat
     1861 aatcggccgt atgttaggta aaccaggtga aattgaagta gggataatta ctgcaataat
     1921 cgggggtcca gtacttattt atgtaactat gaaaaataga ggggttaata actaatgcaa
     1981 aatttaatta taggtattca aaaaagaaaa aatagaataa cactattttc ctcactattt
     2041 ttattaataa taatcagtct atcatttttc attttactta tcggagatga aagttattct
     2101 ttttcaactt tgattaaagt cttaaatagt gaaactgttc ctggagctag tttttcgatt
     2161 atggaaatta gattaccaaa attattagca ggaattatag ctggctggtc ttttggattg
     2221 gcaggattta tctttcaaac tatgttaaga aatcctcttg caagtcctga tataatcggt
     2281 gtcacaagtt cttcatctat tgcagcggtc ttttgcatat tggtattaaa aacaaatagt
     2341 ttaactactg gaattatttc aataacttgt ggactaacat catctttaat attattttta
     2401 ctagctaaaa aagatggttt ttcagcagca agactgataa tattaggtat tggttttcaa
     2461 gctgtcacaa gagcaggcac ctcattttta ttgttgaaag tagcaagata tgaattacaa
     2521 gaagttatga gatggctcag tggctcttta tcttttacaa agttagatga catacctctt
     2581 gttctaatag taagtattat tgctactata ttagttttat tttttaataa aagactagaa
     2641 attattgaac ttggtgaaga aatagcaatc ggacttggag caaatcccga gctttcaagg
     2701 cttgttttaa ttttttgcgc tgtatcttta actgcttttt ctacttcaat tacaggacca
     2761 atagcttgta tatctttttt agctggtccc atagccttaa atattggcaa gaaaagaagc
     2821 ccaatattag ctggattggt tggaatttta ctagttttgt tatcagacat attctctcaa
     2881 aatattttac cagctagata tccagtaggt gttgtaactg gcttgttagg ttcaccatac
     2941 ttaatatact tact
//
LOCUS       DAVKAU010000090         2782 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVKAU010000090 DAVKAU010000000
VERSION     DAVKAU010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2782
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.090"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..431)
                     /locus_tag="VWX48_002000"
     CDS             complement(<1..431)
                     /locus_tag="VWX48_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172549.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLK"
     gene            complement(445..1158)
                     /locus_tag="VWX48_002001"
     CDS             complement(445..1158)
                     /locus_tag="VWX48_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU9172550.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1617..1997)
                     /locus_tag="VWX48_002002"
     CDS             complement(1617..1997)
                     /locus_tag="VWX48_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU9172551.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2419..>2782)
                     /locus_tag="VWX48_002003"
     CDS             complement(2419..>2782)
                     /locus_tag="VWX48_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU9172552.1"
                     /translation="RNKNGQADTNQTEKPQTEKPEEETPREEKPQSEKPESPKPTEEP
                     EESPEESEEPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDN
                     NTIMAEAEKLLALLKESK"
BASE COUNT          855 a          540 c          437 g          950 t
ORIGIN      
        1 ctttttaaag gataatactc tttaatatta ttaacttttt gttcgtaggc atattttgct
       61 acatgatcta ggtatatatc aaaaaagtca tgaggaaaat ctcccataca gccattacga
      121 ttcatattga ggctatattt tcgattagta agataattcg gaaatatatt tcctattact
      181 ctaagattat ctacttgtga atcccttctc ccaatataat ccccttcttt gactaatgat
      241 ggagatttcc aagtaaaaat taaatcgcca gagaaatttt tcttatcaaa aaacttaaaa
      301 agagattgat aaatactatt tgctaattga caagtgtcag atgtaaattc ataattaaca
      361 gcttcattaa aatcaacttc agacatttca atgtactctt caatagtaat attagctttt
      421 tttgtagtca ttagctaatc tcctttaaaa cgtgatcttt tcaagaatat ttttatctaa
      481 acaatccagc aagtcttggt aagaatagac ttcgtaagtc ggctgggctt gtgtgtgatt
      541 ttcgaggtga tgaggattat accagatagt gtcaatcccc gcattattgc caccttgaat
      601 gtcggcggtt agagaatctc caatcatcag cgtcttttct ttactaaatc cagcaatttg
      661 ctggccaatc ttttcataaa aaagagcatc cggcttttga gtttgcaact gttctgagat
      721 aaagacttga ttgaaataag gtgctagacc agattgagcc aaacgtcctg tctgaatggc
      781 agtaatgcca tttgtcgcag catacaagtt ataatcacgc tcaatgaggc tgtccaagag
      841 atcatgagcg cccgatagtg tttgtccctg ctgggcgagg taaaattggt aacgctgggc
      901 aagaaaacta ccgtcttttt cctgtccaaa atgagcaaat aaacgagaaa agcgcgtgtt
      961 aaccagctct tgtttactga ttttcttcag ctccaagtct ttccagagag ccttgttcat
     1021 aggaacgtaa taatctttat aagcctgaat atccgcaact ccttcttctt ttagaagttg
     1081 agtcaaagcc acatcctcag cagcatcaaa atcaagaaga gtgtggtcga ggtcgaagag
     1141 tagaaatttg tagaacaatt tgaggttttc ctttctgaaa attcattaag aacattatat
     1201 cataaagcac ctcatacaat taactaattt aatcacttaa aaaaaattcg aacactttct
     1261 atacaactga cagctcaaat ctttcagaat agaacaatac taactatcga acaccccgtc
     1321 ttcataaata catatgtaat tctaggccta gaattcctat aaactaaatg ctttcatact
     1381 cttccaagta attgattgcc ttaaatttta atttttgaag gtttctaaag ctagaatagc
     1441 cccatcacaa tcagttttga ttgattcaca atttagaaac actatagttt cactcctgtt
     1501 aaaataaaaa ggaactgcat aaagcaatcc ctttctgatt ttgaaatcat ttacttaaca
     1561 ttttatagtt gagataatca atagcttatc tataaaaaga gttatagtaa aattccttat
     1621 ttattgattt caagctccgc taactgtatt tgaataactg acagttctgc accagcctga
     1681 agaagagcag ctgcattata ggcaccttct acaattggaa ccctgttgat gatgatactt
     1741 ttatcactga aatcagtcac catttttaag ttcattttag cagaacctag gtcaaaaaag
     1801 gcaagtaaag tatctgctgg attttcggaa acaaccctat ctacttgatc aaaactcgtt
     1861 ccaattcctc cgccctcggt tcctcctaca taagtaatcg gaacatcttt agctacttta
     1921 ctaatcagtt caacaacacc ttctgcaatg tgtttggaat gtgaaacgat aacaagacca
     1981 ataccaatac tttccatcaa accactccag tttctaaaat agcagtaaag agtaatcctg
     2041 atgagaatga tccaggatca atatgtccaa gaaaccacat gctcctaaga caagagctaa
     2101 cagactggcc atcaataata gtattgttct ttttttcatc attactcctt aactagtgtt
     2161 taactgatta attagccagt aaatagttta tctttattta cactatctgt taagatatag
     2221 taaaatgaaa taagaacagg acagtcaaat cgatttctaa caatgtttta gaagtagagg
     2281 tatactattc tagtttcaat ctactatatt ttgcacattt tcatgaaaaa aatgagaact
     2341 agaactcaca ttctgctctc atttttcgtt ttcccgttct cctatcctgt ttttaggagt
     2401 tagaaaatgc tgctaccttt acttactctc ctttaataaa gccaatagtt tttcagcttc
     2461 tgccataata gtattgttgt cctgggtgcc aaatagtaaa ttatttttta atcctgtgag
     2521 agtctctttg gcattggact tgataattgg atcctggatt tttccaagta aatcttcagc
     2581 ctctctcagt ttttcttcaa ccttttcagt ctcgacctga ggttcttctg attcctctgg
     2641 tgattcttct ggttcctctg ttggttttgg agactctggt ttctcgcttt gcggtttctc
     2701 ttctcgaggg gtttcttcct caggtttttc tgtctgaggt ttctccgttt gattggtatc
     2761 agcttgacca tttttgtttc tt
//
LOCUS       DAVKAU010000091         2731 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVKAU010000091 DAVKAU010000000
VERSION     DAVKAU010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.091"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            49..753
                     /locus_tag="VWX48_002004"
     CDS             49..753
                     /locus_tag="VWX48_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9172553.1"
                     /translation="MGIKNSRGKYISFLDDDDEYMPDRILKLMACFKKSRMKNLALVY
                     SYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIAGTSFWLCKKEVLELINGFEKIDSHQ
                     DGVVLLKLLAQGYQIDIVREFLVNYYAHSKENGITGVTQKTINADEEYYNYCRKYFNL
                     LSFNERILVTKKYYSLNIKRLLLIGDKCKALKVIKKAREEKIFNEFLFLKYMLLYNFG
                     FFYCIYDNYVQLKFRK"
     gene            763..2379
                     /locus_tag="VWX48_002005"
     CDS             763..2379
                     /locus_tag="VWX48_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172554.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          985 a          312 c          500 g          934 t
ORIGIN      
        1 aagttaattt taagtaatga agatttaggt gcaactaatg ccagaaacat aggtatcaaa
       61 aattctagag gtaagtatat atcattttta gacgatgatg atgaatatat gccagatcga
      121 attttaaagt tgatggcttg ttttaaaaag agtagaatga agaatttagc tttagtttat
      181 agttatggaa taataattta tccaaatggt acacgagaag aggagaagac cgattttgtt
      241 ggaaatccct tgtttgttca aatggttcac aatatagcag gtacgtcatt ttggttgtgt
      301 aaaaaagagg tgctagaatt aattaatggt tttgagaaaa tagattcaca tcaggacggt
      361 gttgttttat taaaactact tgctcaagga taccaaattg atatagtgcg agaattcttg
      421 gtgaattact acgctcacag taaagaaaac ggtatcactg gagtgacaca aaaaacaatt
      481 aatgcagatg aagaatatta taattactgt aggaaatatt ttaatttatt gagtttcaac
      541 gagagaatat tggttacaaa gaaatattat tctttaaaca taaagcggtt actattaata
      601 ggagacaaat gcaaggcttt aaaagtaatc aagaaggcaa gagaagaaaa aatttttaac
      661 gaatttcttt ttttgaaata tatgttatta tataattttg gttttttcta ttgtatatat
      721 gacaactatg ttcaattaaa atttagaaag tgagaaacta ttgtgtatac tattataaaa
      781 tcaaatataa aaaaatttag tttattaacg atatttattg ttgctggtca attattgcta
      841 atttatgcag caactattaa tgctctggtg ttgaatgaat taattgcgat gaatttagag
      901 cggtttttga aattgtcaat ctaccaaatg attgtctggt gtgggataat attccttgac
      961 tgggtagtga aaaattatca ggttgaagtg atccaagagt ttaatctaga gattcgaaat
     1021 agagttgcca cagacatctc taactctacc tatcaagaat ttcatagtaa atcatcagga
     1081 acatatcttt cgtggctaaa taatgatgtt cagactttaa atgatcaggc ttttaaacaa
     1141 ctttttttag taataaaagg aatttctggt actatatttg cagttgtgac tcttaatcac
     1201 tatcattggt cattgactgt agccaccttg ttttcattaa tgattatgct acttgtacca
     1261 aaaatctttg catcgaaaat gcgagaagtt agtctaaatt taactagcca aaatgaagct
     1321 tttttaaaat ctagtgagac tatattgaat ggatttgatg tgttagcgtc cttgaatctt
     1381 ttatatgtat tgcctaagaa aattaaagaa gcaggaattt tattaaagat ggttatacaa
     1441 agaaagacaa ctgtagaaac gttagcaggc gctattagct tctttctcaa tatttttttt
     1501 cagatatctc tcgttttttt aacaggctat cttgcaataa aaggaatagt gaaaattggt
     1561 actattgaag caataggagc actaacaggt gttattttta cagcgctagg tgaattagga
     1621 ggtcaattat cctctattat tggtacgaag cctatttttt taaaattgta ttcaattaat
     1681 ccaattgagt caaataaaat gaatgatatc gaaccaaatg aggtgaatag agattttccg
     1741 ttatatgaag caaaaaatat ttgctataag tatggagata aagaaatatt aaaaaactta
     1801 aatttttgtt ttcaacgtaa tgaaaagtat ttaattttag gtgaaagtgg aagcgggaaa
     1861 tctacattat taaaattatt gaatggcttt ttgagagatt atagtggaga attgcgattc
     1921 tgcggggatg atataaaaaa aacctcctat ttaaatatgg tttcgaatgt tctatatgta
     1981 gatcaaaaag cttatttgtt tgaaggtacg attagagata atattttatt ggaagaaaat
     2041 tatactgatg aagaaatact acagtcttta gaacaagttg gtttgagtgt aaaagatttt
     2101 cctaataaca ttttagatta ttatgttggt gatgatggga gattactgtc aggagggcag
     2161 aaacaaaaaa ttactttagc tagaggccta attagaaata agaaaatagt attaattgac
     2221 gagggaactt ctgctatcga taggagaact tcgttagcga ttgaacgtaa gatattagat
     2281 agagaggatt tgactgtcat tattgttacc catgctccgc atccggaact taaacaatat
     2341 tttactaaga tatatcaatt tccaaaggat tttatttaag aatatagggg agggaaacat
     2401 gagattctat tgtgaagctt atgaggtaat tactgaagag aaaaaagtat cattttttta
     2461 tgtagatgag aaacccttaa ggtatctgtt atttgactat atatttctac tagttctagc
     2521 taaaaaaaat atcccaatct tatgaactgc accccaaaag ttagatttat tctgtctaac
     2581 ttttggggtg cagttcattt tgcatagttt tggcattcat cctagatatc catataaaat
     2641 gtctgagatt gttgaaatgt ctaaaaaaat atcaaatcta aacgataaaa aagaatttca
     2701 caaaaagaac tgtgagttga ggtttcaaga t
//
LOCUS       DAVKAU010000092         2704 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVKAU010000092 DAVKAU010000000
VERSION     DAVKAU010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.092"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            212..1189
                     /locus_tag="VWX48_002006"
     CDS             212..1189
                     /locus_tag="VWX48_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9172555.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETATTFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQTHHT
                     MTEEVAAFAHMIQQPDLNLYQTWLDDAGSVHELLYTMRQTAGIRFEAEK"
     gene            1186..2268
                     /locus_tag="VWX48_002007"
     CDS             1186..2268
                     /locus_tag="VWX48_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9172556.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFDPLLTGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKNGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2332..>2704)
                     /locus_tag="VWX48_002008"
     CDS             complement(2332..>2704)
                     /locus_tag="VWX48_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9172557.1"
                     /translation="GESFFLIAGRCNTEWMNAFLEELSQAYPDDYFLLVMDNAIWHKS
                     SILKIPTNIGFAFIPPYTPEMNPIEQVWKEIRKRGFKNKAFRILEDVMNQLQDVIQGL
                     EKEVIKSIVNRRWTRMLFESR"
BASE COUNT          852 a          595 c          471 g          786 t
ORIGIN      
        1 gtgtactatt atagattcaa tatactatat tatagcacat ttttaaatct aggtttacta
       61 gattctctgg ctctatctat ttattcggaa aagaaagctt ttcttcagaa gaaagctagt
      121 agcttatttg aaattttctc ctctctgttg gatagtcccg tctatctatg ttataatgaa
      181 agaaggattt aaaatcggaa aaggagtatt tatgctaaaa ttaggtgtca tcggaactgg
      241 cgctatcagc catcatttca tagaagcagc ccataccagt ggagaatacc aactggtcgc
      301 aatctattct agaaaactag aaactgcaac aacctttgct tctcgctatc agaatatcca
      361 actattcgat caattagaag tcttcttcaa atcttctttt gatttagttt atatcgccag
      421 tccaaactcc ttacattttg ctcaggcaaa agctgccttg tctgctggta aacatgttat
      481 tcttgaaaag ccagctgtca ctcaaccaca agaatggttt gatttgattc aaacagctga
      541 aaaaaataac tgttttatct ttgaagcagc tcgtaattac cacgagaaag cctttactac
      601 tatcaaaaac tttttagcag ataagcaagt gttaggagca gatttcaact atgccaaata
      661 ctcttccaag atgcctgact tgttggctgg acaaacacca aatgtctttt cagaccgttt
      721 tgctggtgga gccctcatgg atttgggaat ttatcccctc tatgctgctg ttcgtctttt
      781 tggaaaagct aatgacgcga cttaccatgc tcaacagctt gacaatagca ttgacctaaa
      841 tggagatggt atcctcttct acccagacta tcaagttcac atcaaggctg gaaaaaacat
      901 cacttccaat cttccttgcg agatttatac aacagatgga accttgactc tcaacacgat
      961 tgagcatatt cgctcagcta tttttaccga ccaccaagga aatcaagtcc agcttcctat
     1021 ccaacagact catcatacga tgactgagga agtcgctgca tttgcacaca tgatccagca
     1081 accagatctg aatctctacc aaacttggct ggatgatgca ggctctgttc atgagctact
     1141 atataccatg cgccagactg ctggcattag atttgaggca gaaaaatgaa aaccaaacta
     1201 ccgactgaat ggcaagaact gagtgaccaa ctcggtttcc aagaattcac ccccattcaa
     1261 actcaactat ttgatcccct tcttactgga gaaaacctcc taggagtgag ccaaaccgga
     1321 actggtaaga ccctagcgta tctcctacca agtcttctca gactacaaaa gaaaaaagcc
     1381 caacaactct tgattctagc accaaacacg gaacttgctg gacagatttt tgatgtatgt
     1441 aaaacgtggg cagaagctat cggattgact gctcaactct tcctttcagg ttcaagtcag
     1501 aaacgacaaa ttgaacgcct taaaaacggg ccagaaattc tgattggaac tcctggccgt
     1561 atctttgaac tcattaaact taaaaaaatc aagatgatga atgtggaaac catcatcctg
     1621 gatgaatttg accaattact agatgattct cagattcact ttgtagaaaa aatcactcac
     1681 tacgcacctc gtgaccacca actggtctac atgagtgcca cgaccaagtt tgaccaagaa
     1741 aagattgtgc cgaatacacg cactattgat ctctctgatc aaaaattgga caatatccag
     1801 catttctaca tgcaggtaga ccaacgtcat cgagtggata tgctacgaaa actggctcat
     1861 gtagaggatt tccgtggtct agtcttcttc aatagcctgt cagaccttgg gaatgccgag
     1921 gaaaaactac agtatcgtga tatattggct gtttccctcg ctagtgatgt taatgttaaa
     1981 tttagaaaaa tcatcttaga aaagtttaaa gataaccaac taaccctgct tcttgcaact
     2041 gaccttttgg ctcgtggaat tgatatcgat agcctagaat gtgtcgtaaa ctttgatatt
     2101 cctagagata gcgaaaccta cacacaccgt gctggccgta ctggtcgtat gggcaaggaa
     2161 ggttatgtta tcactctcgt cactcatcca gaagaaatca aaaaacttaa aaagtttgca
     2221 agtatccgag aaattgtcct aaaaaaccaa gaactctata tcaaataaag ccccattgct
     2281 ctatacacat ccagtgtatg gagctttttt ataagcaatt caattttata ctcatctgct
     2341 ttcaaaaagc attctagtcc atctccgatt aacgatggac tttatcacct ccttctccaa
     2401 tccttgtatg acatcttgaa gttgattcat gacatcttcc aaaattcgaa aggctttatt
     2461 cttaaatcca cgtttacgaa tctctttcca cacttgttca atggggttca tctctggtgt
     2521 gtatggagga ataaatgcaa aaccaatatt agtcggaatc tttaagatac ttgatttatg
     2581 ccatatagca ttgtccataa cgagtaaaaa ataatcatct ggataagctt gtgaaagctc
     2641 ttctaaaaag gcgttcatcc actcagtatt acatctacca gctattaaga aaaatgattc
     2701 gcct
//
LOCUS       DAVKAU010000093         2684 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVKAU010000093 DAVKAU010000000
VERSION     DAVKAU010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2684)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2684)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2684
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.093"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..623)
                     /locus_tag="VWX48_002009"
     CDS             complement(<1..623)
                     /locus_tag="VWX48_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172558.1"
                     /translation="MVEIKNLSLDYGEKHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDR"
     gene            complement(611..1168)
                     /locus_tag="VWX48_002010"
     CDS             complement(611..1168)
                     /locus_tag="VWX48_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9172559.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            complement(1069..1698)
                     /locus_tag="VWX48_002011"
     CDS             complement(1069..1698)
                     /locus_tag="VWX48_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9172560.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            complement(1709..>2684)
                     /locus_tag="VWX48_002012"
     CDS             complement(1709..>2684)
                     /locus_tag="VWX48_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172561.1"
                     /translation="SFISLAVVIFVGVNLIINKEINSLYLIGYLLAAMKIKDSLDASK
                     EGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKDVEFAYNKDAKVLNGVSF
                     KAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGKDIKEISTESLFDKVSIV
                     FQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIEKMDKGFDTVIGENGAEL
                     SGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQESLNNLVKDKTVVIISHRM
                     KSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTKMAEEFIY"
BASE COUNT          853 a          520 c          338 g          973 t
ORIGIN      
        1 cggtcaacta tgtccatcaa ataataaatt ctatgctctg caacaattat gcttatgcct
       61 ttctctttta atatctttag catctttgcc aaaacactta tgcttttaat atctaaattc
      121 gatgaaggct catccataac tataatcttt gtacctgcta tataagaagc tgcaatgcaa
      181 agaatttgtt tttcaccgcc ggatagatta aatatatttc tgttcaaaag attttttatc
      241 gggaatatct caagtatatc cttcaaacgc ctgtccatct cttctcttgc aagaccgata
      301 ttttccaaat aaaataataa ttctaatgtc gtattgacat taaaaaaata tgtcttagga
      361 ttttgaaaaa cagttgaaac aagcattgag atttgataaa gttccaaatt ttttatattc
      421 ttaccatcaa taattatttc gccctttgtc tttgcgttat cataccttac agctagtcca
      481 ttgattgaat ttattaaaga tgacttacca tttccacttt ttcctgtaaa tagcacgcac
      541 tctccctcgg ctatggatag tgatatatca tctaatatat gcttttcacc ataatcaaga
      601 cttaaatttt ttatttcaac catattaagc ctcccacaat aagtccagca accgctaaaa
      661 cataaacaaa atcaattagc tgtatcttta cgcgaatgta tctggtctta gcaattggat
      721 tttctattgc ctttgtttct gccgcttttg caatgtcatc tgatatatta gatgatataa
      781 tgagtagtgg tacagaaaca tattcaagat atttgactgg gtttttaaaa tttatccctc
      841 ttactctcat agccattttg atgtttttct tctcctcctt aaaagatggg aagaatctaa
      901 acataaccgc aataggtatg gatacattct ttgaaatctt aagcttatcc atcgatgaaa
      961 ttattgcgcc tacatccgag gtctttatca taaagcttgc tgccataaat ggtaaaataa
     1021 acattctaat aacaataggt atactcaaaa acatcttaac tatagggttt aattcagata
     1081 acaccataaa attaggcaag gagtaaagta tcccacacaa tataatccat ttgaaaagtg
     1141 ttttttcaat agagccttgc ctatatatgc tccaagaatt cctcctaaga aagcacctaa
     1201 ggctactaaa gccatgtgag gataagttat taacttttct aatacatcaa cataatcttt
     1261 tcccatcgtc atcaaagacc actccatata tttttctttt gctaaaagca tttgcattaa
     1321 agagctacat atccatgtgc tgaagattgc ataagaaagc atattgtatt taaatgaatt
     1381 ataattacca atctttctaa ttaattctgc tattatcatt actataagtg ataaaaccac
     1441 aactacgtag gtatgaccag ctgcaaacat cacaagtggt gatatcatac caaatataaa
     1501 tagtgcccat ggcttttgaa ccttagccat aaataacata acaacagttc ctgcaactat
     1561 ggctaatact gtcgggtata ttaagaacaa tattggaatc aagcccatca taccaactcc
     1621 aaacatgaag gcaaaataaa ttacgccaaa aacaccgata cttactaaat cttttacttt
     1681 taatttttta ttatccattg tagtcctcct aataaataaa ttcttctgcc atttttgtct
     1741 tttctattaa atttttgtaa atttttgatt tttgtaaaag ctcttcatgc ttaccttcgc
     1801 tttctactct tccgttttga agaactacta tcttgtctgc attttctatg gatttcattc
     1861 tatgtgaaat gattacaaca gttttatctt taactaaatt atttaaagac tcttgaatct
     1921 ttttctcgtt gttaacatca aggcttgctg ttatctcatc taagatcaat atcggcgcat
     1981 cttttaagaa ggctctggct attgataatc tttgtctttc tcctcctgat agctcagctc
     2041 cgttctcacc aataactgta tcgaaacctt tatccatttt ttctataaaa tctgtgcaat
     2101 ttgcaagttt tgctgctctt ttaacctctt cgtcacttgc atcttgcttt ccgattctaa
     2161 tattttccat aatgctttga ttaaagagaa ccacatcttg gaaaactata gagaccttat
     2221 caaaaagaga ttctgttgat atttctttta tatctttgcc atcgattaag atttgtccct
     2281 tgtcataatc ataaagtctt gatataagtt tcaagatagt tgttttaccg cagccacttg
     2341 cacctaccaa agcagtgacc tctccctgct tagctttaaa acttacacca tttaaaactt
     2401 ttgcgtcttt attgtaggca aactcaacat cttttagatc aatatcaaat ttttttaagc
     2461 tatagtcatc gccttcttgt aaatcttgat tttgaatttc ttttaatctt tctattttgg
     2521 gcgataaata aaatatttcc atcaagccct ctttagatgc atctaaagag tcttttatct
     2581 tcatagcagc tagtaaatat cctataaggt agagagaatt tatctcttta ttaataatta
     2641 gatttacgcc gacaaatatc acaacagcaa gagatataaa gcta
//
LOCUS       DAVKAU010000094         1650 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVKAU010000094 DAVKAU010000000
VERSION     DAVKAU010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.095"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            72..527
                     /locus_tag="VWX48_002013"
     CDS             72..527
                     /locus_tag="VWX48_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9172562.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVYAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            692..991
                     /locus_tag="VWX48_002014"
     CDS             692..991
                     /locus_tag="VWX48_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU9172563.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1252..1575
                     /gene="tnpB"
                     /locus_tag="VWX48_002015"
                     /pseudo
     CDS             1252..1575
                     /gene="tnpB"
                     /locus_tag="VWX48_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          566 a          325 c          289 g          470 t
ORIGIN      
        1 gattatacca cattgtgtac tatttttggt tcatttcact ataataataa cgatactaga
       61 taatgaggaa aatgcaatgg caaacccaac tttcggagaa aaaagcgaat acagactata
      121 ttgctcgcta tggcgtatat gcagttatcc ctaatcctga acaaaaacaa attgttcttg
      181 ttcaagaacc aaatggtgct tggttcctac catgtggaga aattgaagca ggtgaaaatc
      241 atcaggaagc cctaaagcgt gagttgattg aagagcttgg tttcacagca gaaattggta
      301 cctattacgg acaagctgac gaatatttct attctcgtca tcgtgatacc tactactaca
      361 atcctgccta cctctatgaa gcaactcctt tcaaagaagt acaaaagcca ctagaaaact
      421 ttaatcatat tgcctggttc cctattgacg aggctatcaa aaaccttaaa cgtggtagcc
      481 ataaatgggc cattgaatct tggaaaaaac agcataagat tgactaatac tcaatgaaaa
      541 taaaattcaa accacgtcag cgtcgcctta ccgtactcaa gtatagcctg cggctagctt
      601 cctagtttgc tcttttattt tcattgagta taaatcaagc gactttattc aaaaagtgct
      661 ataatagaat tagaaaatcg gaggaaatat tatgaagctt atcaatacga caaactcaca
      721 ctcgcaactt gtaaaaagtc agctagaaag taccgatgca acccttgttg aggtttattc
      781 tgcagggaat acagatgtta tttttaccca agctccgctt cactatgaaa tcctcatctc
      841 aaacaaacac cgtgctattc gtgagcctga aatcgaaacc attcaagaat ttttcttgaa
      901 acgtaaaatt gataagacct ctgttgatga agccaatatc aagacactct actcagagaa
      961 attaattgga atttcaatcc caatcaagta agaaaattga gtaaaaactc gatttgagag
     1021 aaagtccaat aagtctttcc ataataaaac gcatagtagc aagagtttct acacccacta
     1081 ttatgcgttt ttatcatttt gaaatctact gctaatcaat gaagaagcaa agatcaaact
     1141 aggcagctag ttacaagtta cgtaagcgcg tcataacaag gtatctatcc taattcccca
     1201 acttccagta tactagataa aaaataatta tcggaggaaa ggtattgtac tatgataatt
     1261 caactaagtg atttaggtca agttcacctt gtttgtggca agacagatat gaggcaggga
     1321 atagactcat tagcctatgt agttaaaacc cactttgaat tggatccttt ctccggtcaa
     1381 gcctttctct tttgtggtgg acgtaaagac cgctttaaag ccctttactg ggatggtcaa
     1441 ggattttggc tactatataa acgctttgag aacggaaaac tgacttgacc aagtacagaa
     1501 aaggatgtca aagctctcac accagaacaa gtagactggc ttatgaaggg cttttctatc
     1561 actccccaaa tatagtggat ttaaactaga atagtacacc cctacttcta aaacattgtt
     1621 agaaatcgat ttgactgtcc tgatcaattt
//
LOCUS       DAVKAU010000095         1629 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVKAU010000095 DAVKAU010000000
VERSION     DAVKAU010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1629
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.096"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..225
                     /locus_tag="VWX48_002016"
                     /pseudo
     CDS             1..225
                     /locus_tag="VWX48_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            607..1100
                     /locus_tag="VWX48_002017"
                     /pseudo
     CDS             607..1100
                     /locus_tag="VWX48_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452046.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1116..1328
                     /locus_tag="VWX48_002018"
     CDS             1116..1328
                     /locus_tag="VWX48_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172564.1"
                     /translation="MKLNKFNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHAN"
BASE COUNT          560 a          203 c          293 g          573 t
ORIGIN      
        1 gatcgagttg aattttatgg ttcaggtttc cgtcattttg aaacctatat tgaagatttg
       61 catgatgcca aaggcaataa aatcgaccgc gctccaaatc caatggaact attgactatt
      121 aaagtcccat aacctgttca atcaggagac atggttcgtg cattaaaaga aggactcatc
      181 aatctttata aggaagatgg aaccagcgtc acagttcgtg cttaatgtag ttgtttagtt
      241 ttaaaaaatt atgcaaagct ccatatacaa cacttaaacg agattaaaga atggcgaaat
      301 cccttgatgc gcaagagatt agctgtcctt ttttattttt taagtgataa agtcggagct
      361 taggtatcaa agcctatcaa attaaacaaa gaagcgatgt cttagatatt ttgaaaaaaa
      421 ttaataagca aaaaactctc tattattttg ttgtagagag ttttttgtta ataaaatttt
      481 acaaaatgac atttatatat tgcattaagt tagatatatg atataatgtt gttaaaaaga
      541 ggcgcaactt tttaaactca ataagaatca aagagcaaac catgaatatt aattgaggaa
      601 taaaaaatgt aagttataaa tgtaagtaag cattatggtc attcaatcat tctcaaagat
      661 ataaattttg cacttaacaa gggtgaaatt gttggtcaag tagggagaaa tggagttggt
      721 aagagtacgt tgatgaaaat tcttgttcag aataatcaac cgacttcagg taatattata
      781 agcagtgata atgtattgaa gaaatttgtg agagggttct tttcttggag agcgggcttt
      841 tgacatttca aaaagtagga aaagatagtc ataatttctt gtttgagata gctttttcat
      901 cagctacaga tagagacatt ttcattacca aacaagaatt tggggatatt gttcaggaag
      961 agggactgag aattactatg tctgggaata ttcaaagtag tgagcttttt aaatttttta
     1021 acgaaaactc tattaaagta gttgattttg aaactaaaaa agagacgctt aaagatattt
     1081 atctaaatcg ttcaaaataa aggaaggtta taatcatgaa attaaataaa tttaattttc
     1141 ttaaggaaaa tataagaaat ttatattcat caggtgtaat atatctcggt ttgcttatct
     1201 catttatacc gccgatattg gttacattct ttattctaaa gactcaaggg acatcgcttg
     1261 gtattaagca tatttcaaac ttttatgcta tgctcggtat gttaatggct gttatacatg
     1321 ctaattgagt cattagtaga gatttttccc acaatacggt aagtttgttt tataatcaac
     1381 agaagaatcg gatgatttac gtcttgtcta attttctata tgccatctca gtttccatta
     1441 tttatgcttt gaatggcatt gtgttactag tcatagtaag taaattgggt attccaggtg
     1501 atttaggatt agattttata gtagctattg tagtcaatac aattttgtta gtcctgtttt
     1561 attttctatt atcttacatt ttctatttat acaaattgaa aagtggcttg gtatttggta
     1621 ttttagtag
//
LOCUS       DAVKAU010000096         1611 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVKAU010000096 DAVKAU010000000
VERSION     DAVKAU010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.097"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(192..>1611)
                     /locus_tag="VWX48_002019"
     CDS             complement(192..>1611)
                     /locus_tag="VWX48_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9172565.1"
                     /translation="LLSLYPTLKNFAKYDCIFVDDEDLMHTLLDLFDWFTIIDRPKIC
                     LIGSRVWFEKRNLFYIHLDYRILALNTAENLESRNSSIVPVKDGKQILIDQLFDGECD
                     DIYLLTVHSPMNKALEILSEKYKQISGKNIKIIEKRYDELLEMIESGDVSSSFDMIRM
                     DMAWLPTFGKKYFQEITSFRQTKSINQNISKSVSREYMYIDQKQYTFPLDVSSQILVY
                     RKDLFEDSFLQRRYFEKTKRKLTVPKSYQEFDELSEFFTLTENPFSPTLYGHSLALSS
                     SVRAACEFIPRFRERLAQSRMNLAVLPQVLTEYEKSYQFTEKSFNSSWNDFVTNLNSG
                     KTSMEIIFSNYTSPLFDGLNVSAQFEFATATIPGNTPVIGGGSIGISKYSNRVEECLN
                     FINWLYSEEISILLTSLGGFLPSKYVMQNRMLQFQYPWLSSLEDTFSIGSRTKWYGFN
                     TDFRFEQMLGQELIESVKHRYG"
BASE COUNT          580 a          274 c          192 g          565 t
ORIGIN      
        1 atcagttaat tgtttacttg cttcatcatt catagaacta ctataccata ttttgtttcg
       61 caggaagtct aataaaataa ctttgcaata aaaaaatgtc aaaataataa ttttaaatat
      121 aattggtgtt tacttgaatc tttaatttta aacaataata aataaactag taataaaaat
      181 ttagtattaa tttatccata tctatgcttc acactttcta ttaactcttg ccctaacatc
      241 tgctcaaatc taaaatcagt attaaagccg taccattttg ttctactccc aatactaaat
      301 gtatcttcta aactagataa ccatggatat tgaaattgta acatcctatt ttgcatgaca
      361 tactttgatg gtaaaaaacc acccagagat gttagtaaaa tagaaatctc ttcagaatat
      421 aaccaattaa taaagtttag acattcttcc actctatttg aatatttaga aattccaatt
      481 gagccaccac ctatcacagg agtattacca ggtatagtgg cagttgcaaa ctcaaactga
      541 gcagaaacat tgagaccatc aaataatgga ctagtataat ttgaaaaaat tatttccatt
      601 gaagttttac cactgtttaa gttcgtaacg aaatcgttcc acgaagaatt aaatgatttt
      661 tcggtaaact gataactttt ctcatactca gttaaaacct gaggaagtac agcaagattc
      721 attctagatt gtgctaatct ctcacgaaac cgaggaataa attcacatgc tgctctcact
      781 gaagaactta aagctaaact atggccataa agtgtaggtg aaaatggatt ttctgttaat
      841 gtaaaaaatt cacttaactc atcaaactct tgataacttt ttggtacagt taattttctt
      901 tttgtttttt caaagtatcg tctttgtaaa aatgaatctt caaataagtc ttttctatat
      961 actaaaatct gactactaac atccaatgga aaagtatatt gcttctgatc aatatacata
     1021 tactctcgag acaccgactt agaaatattt tgattaatac tttttgtttg tctaaagctt
     1081 gtaatctctt gaaaatactt tttcccaaat gttggaagcc aagccatatc cattctaatc
     1141 atatcaaaac tggatgaaac atcgccagac tcaatcatct ccaaaagttc atcatatctt
     1201 ttctcgataa ttttaatatt tttcccagaa atttgtttat acttttctga taaaatttct
     1261 aaggctttat tcattggtga atggacagta agtaaataaa tatcatcaca ttctccatca
     1321 aataattgat caattaaaat ttgtttgcca tctttaactg gtacaattga actatttcta
     1381 ctttctaaat tttcggcagt attgagtgcc aatattctat aatctaaatg tatataaaaa
     1441 agatttcttt tttcgaacca aacacgtgaa cctatcaaac atatttttgg tctatcaatt
     1501 atagtaaacc aatcaaataa gtctaatagc gtgtgcatca aatcttcatc atcaacaaat
     1561 atacaatcat actttgcaaa gttttttaga gtaggatata gagacaacaa t
//
LOCUS       DAVKAU010000097         1575 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVKAU010000097 DAVKAU010000000
VERSION     DAVKAU010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1575
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.098"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            26..1372
                     /gene="gdhA"
                     /locus_tag="VWX48_002020"
     CDS             26..1372
                     /gene="gdhA"
                     /locus_tag="VWX48_002020"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU9172566.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWNYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          476 a          305 c          329 g          465 t
ORIGIN      
        1 aatatgacaa taaaaggaga acgatatgac atctgctaaa gaatatatcc aaagcgtgtt
       61 tgaaactgtg aaagctcgta acgggcacga ggctgaattc ctccaagctg ttgaagaatt
      121 tttcaacact ttagaacctg tatttgaaaa acaccctgag tatatcgaag aaaatatctt
      181 ggcacgtatt actgagcctg agcgcgtgat ttctttccgt gttccttggg ttgaccgtga
      241 tggaaaagtt caagtaaacc gtggttaccg tgttcaattc aactcagctg ttggaccata
      301 caaaggtgga cttcgtttcc acccaactgt aaaccaaggg atcttgaaat tcctcggatt
      361 tgaacaaatc tttaaaaatg tcttgactgg acttcctatc ggtggaggta aaggtggatc
      421 agacttcgat cctaaaggta aaacagatgc tgaagtgatg cgcttctgcc aaagcttcat
      481 gactgaattg caaaaacaca tcggaccatc acttgacgta cctgctggtg atatcggtgt
      541 tggtggacgt gagattggtt acctttacgg tcaatacaaa cgtcttaacc aatttgatgc
      601 tggtgtcttg actggtaaac ctcttggatt tggtggtagc ttgattcgtc cagaagcaac
      661 tggttacggt ttggtttact atactgaaga aatgctcaaa gctaacggta acagctttgc
      721 tggtaagaaa gtcgttattt caggttctgg taacgttgct caatatgctc ttcaaaaagc
      781 aactgaactc ggtgcaactg ttatttctgt ttctgactca aatggttatg tcatcgatga
      841 aaatggtatc gacttcgatc ttttggttga tgttaaagaa aaacgtcgtg ctcgtttgac
      901 tgagtatgca gctgaaaaag caactgcaac ctaccacgaa ggtactgtat ggaattacgc
      961 tggaaactat gacattgctc ttccatgtgc cactcaaaac gaaatcaacg gtgaagcagc
     1021 taaacgtttg gttgctcaag gcgttatctg tgtatctgaa ggtgccaaca tgccgagcga
     1081 ccttgatgcc atcaaagttt acaaagaaaa tggtatctta tacggacctg caaaagctgc
     1141 caacgctggt ggtgtagccg tttcagctct tgaaatgagc caaaacagtc ttcgcctctc
     1201 atggactcgt gaagaagttg atgaccgtct caaagacatc atgacaaaca tcttcaacac
     1261 agctaaaacg acttcagaaa catacggtct tgataaagac taccttgcag gagctaacat
     1321 tgctgccttt gaaaatgtag caaacgctat gattgcccaa ggtattgttt aagatttatt
     1381 tgcttaatcc tcaatcacta cgattgggga tttttagttg agttagacag ttgggaaatt
     1441 ctaattaaat gaaataaaaa ctgaacaaat tgattgcgga attcaaacca atttctaaca
     1501 tatttctaga aattaatttg acttttctaa tcgatttgtt catatcttat ttcaatttac
     1561 tatacttact taacc
//
LOCUS       DAVKAU010000098         1470 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVKAU010000098 DAVKAU010000000
VERSION     DAVKAU010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1470
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.099"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            132..>1470
                     /locus_tag="VWX48_002021"
     CDS             132..>1470
                     /locus_tag="VWX48_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEU9172567.1"
                     /translation="MNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPN
                     ELHKLIEKIAPKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGD
                     FSKKNIVLKEDDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNT
                     FKLDAKNAYFYTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLE
                     VLSENRSQDVNNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQ
                     LRFEIDGHEELRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKA
                     KFRELANIAFRQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILN
                     SVTGDEKKIIEFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNH"
BASE COUNT          557 a          173 c          262 g          478 t
ORIGIN      
        1 ataatttatc tataactcaa ataaagaatt ctattaaaga aaattcctta gttttgtttg
       61 ttgatgcagg aatatcagct aattctaatc taccaacttg gggagaattg attcaatcat
      121 taaaaaaaga attgaacata ccagaagaaa gaacagatag tccactgaga attgctcagt
      181 attattatga tacttttggg aaaaatcagt acacaaagaa gatagaagaa attttcttta
      241 agaagggatt gagtaaacca aatgagttac ataaattaat agaaaaaatt gcaccaaaac
      301 atattattac gacaaactat gattcacttc tggagagtca atttgaaagt ggcttgttaa
      361 agtacaatgt agtcgctgag gataaagaca tcccttatac gagttcggaa agatacttga
      421 ttaaaatgca tggtgacttc agtaagaaaa atattgtttt gaaagaagat gattatttag
      481 actatcattt gaacttccca atgatttcta ctttaatcca gtcattgata atgaatcata
      541 ctctattgtt tgtggggtat tctctaagtg attcgacttt taattcaatt tttagaatga
      601 ttcaaaatac atttaaattg gatgctaaaa atgcttattt ttatactccc gaggaaccgt
      661 ctatgatcat tcgagagtat tataagaagc aaggaatttt cattatctct aatgaagaga
      721 atctaggtca ggagacatca gaaaaacaga acaaattgta ttgcaggaca aaagattttt
      781 tagaggttct atcagaaaac cgaagtcaag atgtaaataa tgctgatgat ttatggaatc
      841 aactggcttt tttagataga cttagtttta ttgatgcgaa agatttttct agatattctg
      901 atttaaagaa aagggcttta aactgggatg atgagtattg ctggtttgga aatgatcaat
      961 taagatttga aattgatggt catgaagaat tacgaattat ggtatctaaa aaatctttat
     1021 taaatcgctt tctagatatg gagattggtg agcctaggga tttaaagggg aatcgattct
     1081 taagtaaggc ttttaagttg tatgaagaaa aacaatattc tttagcaaaa gcaaaattta
     1141 gagaactagc taatatagca tttcgtcaga aagactattt taatttctta gtttgtgaat
     1201 ttaattttca gcaaattcaa ataattgata gatacgaaaa aacacctagt tatgcagagc
     1261 cactttatga tggagaatta agcgaattaa cagaacaaat tcttaactcg gttacaggag
     1321 atgagaaaaa gattatagaa ttttttagag attcaatcct taacttcaat tttttatata
     1381 gaaaattaga aactattaat gaattatttg atgaaattcg tgaagagcat gaaagctata
     1441 gaagaggagg atggtctgct aataatcatc
//
LOCUS       DAVKAU010000099         1313 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVKAU010000099 DAVKAU010000000
VERSION     DAVKAU010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.100"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            30..827
                     /locus_tag="VWX48_002022"
                     /pseudo
     CDS             30..827
                     /locus_tag="VWX48_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(862..1071)
                     /locus_tag="VWX48_002023"
                     /pseudo
     CDS             complement(862..1071)
                     /locus_tag="VWX48_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1237..1310)
                     /locus_tag="VWX48_002024"
     tRNA            complement(1237..1310)
                     /locus_tag="VWX48_002024"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1274..1276),aa:Asn,seq:gtt)
BASE COUNT          435 a          272 c          207 g          399 t
ORIGIN      
        1 ttctgatttt ctagtataaa aaaattcaaa ctagaattct tcttagaaaa ggccgtttta
       61 agtgctatca ttgctcaaaa atggagctcg ctgagacttc tatcgtcaag aagaatcatc
      121 aaattccttg tatcatcaac caaaagattg ctcagaagct aattaaaaag acttctatga
      181 ccgacattga tcatcagttg tctatttcaa cttcaactgt cattcgcaag atcaatgatt
      241 ttcactttga gcatgatttt tcgcgtcttc ctgagattat gtcctaggac gttgaaacag
      301 tccggggagt gactgtttca atcgggagat ggagatgagc tttattgctc aagactttga
      361 taagctcaat atcataactg ttcttgagag cagaacacaa gccatcatcc gaaatcccat
      421 gaatacaagg ctatcaagcg atactgaaag ctcattcaac aagatagtca gaaactgagt
      481 gataaacgat tttatcgccc tacttttcgt atgcacttga ctaataaaga aattctagat
      541 aaacttttga gctattccga agacttgaaa caccactata atctctacca gctcttgctt
      601 ttccacctct ttttcagact ctgtttaaaa ccttcctcaa agataaagag aaaatcgtca
      661 acgcccttca attaccttat tccaacgcca aactggaagc caccaataat ctcatcaaac
      721 ttatcaagta caatgccttt ggttttagga actttgaaaa cttcaaaaaa gaaaggacga
      781 aatttgtcct ttctagatct tcgctttctt caacccacta cagttgacaa agaaccgaaa
      841 aatgtctcgc ctctaatata gtcaattgaa acaagaacaa gacaaaagag cctcataaaa
      901 ggtattgcaa cttggtaata cctttttggg gttctttttg atatgaaccc atgttttctc
      961 aataggattg tactcaggtg agtagggagg aagaggtaaa agtttatgcc caaactcttc
     1021 acacaagagt tctagcttac ccattctatg gaatcttgca ttgtccataa tatagtagat
     1081 tgaaactaga atagtacacc tctacttcta aaacattgtt agaattcgat tttactgtcc
     1141 tgatcgattt gtcctattct tatttcattt tactataaca cgaaatagat tattattaca
     1201 taacaaaaaa gaggtctaaa cctcttaact aaattactcc gccagtagga ctcgaaccta
     1261 cgacatcatg attaacagtc atgcgctact accaactgag ctatggcgga tta
//
LOCUS       DAVKAU010000100         1242 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVKAU010000100 DAVKAU010000000
VERSION     DAVKAU010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1242
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.101"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..110
                     /locus_tag="VWX48_002025"
     CDS             <1..110
                     /locus_tag="VWX48_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU9172568.1"
                     /translation="KDQISSTVLPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            76..390
                     /locus_tag="VWX48_002026"
     CDS             76..390
                     /locus_tag="VWX48_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172569.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1075..1236
                     /locus_tag="VWX48_002027"
     CDS             1075..1236
                     /locus_tag="VWX48_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172570.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
BASE COUNT          521 a          158 c          232 g          331 t
ORIGIN      
        1 ataaagatca aatatctagc acagtattgc cagatatcaa aattaaatta ccgatagaca
       61 gtagaggtac tccagattgg aattacatgg aaagatatag agatagataa agagagagag
      121 ggagagatag ataaaaagtc cacccccatt ttttatggag aattcaaaaa tgtaaggtta
      181 agcaaagaag aatataaaaa tctaaaagaa aaattaaact cacacacaga tataatgata
      241 aataaactat ccagatacat ggaaagcagt ggtaagacct atcaaaacca ctatgtgaca
      301 atcttaaaat ggtatgaaga agataaagac aaactaagac agaaaggttt aaataaaaaa
      361 atgaattatg atgtaggaga atctttatag ataaaaagag gtggaaaggc actattaaag
      421 actttaagtc taaaaaggta tcaaagtatg ccagagataa aaaaaatata aatatgacac
      481 tttaaaggcg attagaaaat taaagaaatg ctagaagact tttagatgac agttaccaag
      541 agggtctaat tttcactgct atttatgcag tgggaattgg acctttttat ataagcaaat
      601 tctatttcaa aattggttac caagaaagac ttcttttcac tgttaagtat aagagggtaa
      661 tttatagaat tttgttacat caagataaat attttctgat ggtcaaattt taaaaagatt
      721 aataactctc gataaatttt gaaccttaac aattgaatag accaagacaa gacgttaatt
      781 atttttggag cgtaataacc tatccgtcaa gatctttcgg ctgaataatt cggcaaaaaa
      841 agttctgcta agcaaaaaga aagtgagcga taagtaagag tttgaatata gggagggata
      901 ccctatccgc tatgaagaaa atgagggtaa tgatacttct aaggttgaag ccggctcatc
      961 cggaatagag gcggaagtga gattcctatg ttgctaatcc aaagcacttg tcaatgtcaa
     1021 aaaacttaat taaacaaata attattagat ataaaacttt agaggaggta tatattggac
     1081 aatgactgga atggattggc tgatttaata gcaaatctga ttgcaaaata tgctggtgct
     1141 ttagatttag ataatctacc cgatccaacg ccagcaaaaa atcaagagat gaaaaatagt
     1201 tttgacatgg caaaaacaca aattgagacg gactaataaa ag
//
LOCUS       DAVKAU010000101         1077 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVKAU010000101 DAVKAU010000000
VERSION     DAVKAU010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1077
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.102"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            470..>1077
                     /locus_tag="VWX48_002028"
     CDS             470..>1077
                     /locus_tag="VWX48_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9172571.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRW"
BASE COUNT          314 a          181 c          228 g          354 t
ORIGIN      
        1 gagctttttt ctttttaaat attgattgtt tctaaaagtt ctagtaatat tgctatttct
       61 catttttcca aatatgttat tcaacttatt agctacgtct ctattcatat ttgggtataa
      121 aacaaaaaat caattctaac agttttatat cagaataata aataaaaaag cgatattcta
      181 gactgtatca atccttttcc attataggag caacagagtg ggagtagtca tctaaggact
      241 aatttatata tttttacgag tcagtatctt gggatactgg tttttacttt tttagacttt
      301 ttgactactt gttaaaactg gggtaatttt cgactgttta atagttatta tgcaaagtct
      361 aaaagattag aattgtcaaa acaatccgtc taggcttgat tttatccttt atttactata
      421 aaatgagaag gaaaaatgtc aaacttttat attgcaaata ggagaaatta tgacaaaaac
      481 attaaaacgt cctgaggttt tatcacctgc agggacttta gagaagctaa aggtagctgt
      541 tcagtatgga gcagatgctg tctttatcgg tggtcaggcc tatggtcttc gtagccgtgc
      601 gggaaacttt actttcgaac agatggaaga aggcgtgcag tttgcggcca agtatggtgc
      661 caaggtctat gtagcggcta atatggttat gcacgaagga aatgaagctg gtgctggtga
      721 gtggttccgt aaactgcgtg atatcgggat tgcagcagtt atcgtatctg acccagcctt
      781 gattatgatt gcagctactg aagcaccagg ccttgaaatc cacctttcta cccaagccag
      841 tgccactaac tatgaaaccc ttgagttctg gaaagagcta ggcttgactc gtgtcgtttt
      901 agcgcgtgag gtttcaatgg aagaattagc tgaaatccgc aaacgtacag atgttgaaat
      961 tgaagccttt gtccatggag ctatgtgtat ttcatactct ggacgttgta ctctttcaaa
     1021 ccacatgagt atgcgtgatg ccaaccgtgg tggatgttct cagtcatgcc gttggaa
//
LOCUS       DAVKAU010000102          953 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVKAU010000102 DAVKAU010000000
VERSION     DAVKAU010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..953
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.103"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            71..253
                     /locus_tag="VWX48_002029"
     CDS             71..253
                     /locus_tag="VWX48_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9172572.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            263..616
                     /locus_tag="VWX48_002030"
     CDS             263..616
                     /locus_tag="VWX48_002030"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9172573.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYETKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIENKKQG"
     gene            624..>953
                     /locus_tag="VWX48_002031"
     CDS             624..>953
                     /locus_tag="VWX48_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU9172574.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWN"
BASE COUNT          390 a          119 c          158 g          286 t
ORIGIN      
        1 aaaaatcgaa aaattagcta agaaatattc tgataactta aacatcaaag ttcaagagag
       61 agttcgtgaa atggcaaatg ataataagag ccattatttg atatacagag ttttaggtat
      121 ttcatttgaa gaaggagaaa atatcgattt gtatcaaaat aaaggtcgtt ttttatacaa
      181 atatgctggt tcatttttag aagaagctgc agtactatcc tttaacgaaa aatttggtac
      241 agaaaatact taaaaagtta acattcctaa ttctgaaagt acaaaaccta agacttttga
      301 aattgattgt ttagtcggag aaaaacacgc atacgaaaca aaatggtggg atgcaactac
      361 agatggagac catataacta aagaacacac tagaataaaa gttattcata acaaaggata
      421 tataccaatt cggttaatgt tctactatcc aaatagaact caagctataa aaattcagca
      481 aactttagaa acattgtata acggtattgg agggaaatat tattatggag attctgcctg
      541 ggaacattta agagcagtga ccggtattga tttacttagt attctaacag atattgaaaa
      601 taaaaaacag gggtaaaatc aaaatgacag tattaaaagg agataactta gaaatattaa
      661 aaactattga atcctcaagt attgatttaa tctatatgga ccctcctttc tttacacaga
      721 aaacccaaaa attatctaat aacaaaaata ttatgtattc attcgaagat acgtggactt
      781 cgattgagga ttacaaagaa tttttgtctg taagattaga agaatgcaaa agagtgctaa
      841 aaaatagtgg cagtattttc gttcattgtg ataaaattgc aaatcatcat attagattaa
      901 ttttagataa tatctttgga gcagatatgt ttcaaagcga aattatatgg aac
//
LOCUS       DAVKAU010000103          892 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVKAU010000103 DAVKAU010000000
VERSION     DAVKAU010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..892
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.104"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            21..497
                     /locus_tag="VWX48_002032"
     CDS             21..497
                     /locus_tag="VWX48_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9172575.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKSVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEAIA"
     gene            535..837
                     /locus_tag="VWX48_002033"
     CDS             535..837
                     /locus_tag="VWX48_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9172576.1"
                     /translation="MIKILAACGAGVNSSYQIKSALEEELSNRSYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIRLPAKQNMV"
BASE COUNT          302 a          156 c          171 g          263 t
ORIGIN      
        1 tggaaagaag ggaaaacctt atggtattag attatttctt tgacaaaaac cttgtgtttt
       61 gcttagaagc ggataatcaa gaacaactct ttgatcaggt agcaagcttg ttggaagaac
      121 gagaaattgt cactccaact tatcgtgaag ccttgatcac gcgtgaaaag tcatttccaa
      181 ctggtttaga tatggaattt ctaggaaagg acttgccaaa tgtagcgatt cctcacacag
      241 atattgttca taatctagct gaaaaagtgg tggttgttcg attagaaaaa tcagtaactt
      301 ttcacaatat gatagctcct gataaggaag tagaagtatc cctactcttc tttatcatta
      361 acaattcaag ttcaagtcaa acaaatattc tggctcagtt gatggacttt ttcacaggaa
      421 atggacatct tgaagattta tcaaaaattt ccgaaccaga aaaactttat gcttacattg
      481 ctgaagcaat cgcttaatct tgtctattaa aaaataaaat cggaggaaat ccaaatgatt
      541 aaaattcttg ctgcctgcgg tgcaggtgtt aactcaagtt accaaattaa aagtgctcta
      601 gaagaagaac tttcaaaccg tagttatgat gttcactgtg atgcagtcat ggtgaaagat
      661 gtaaacgaag accttatgaa aggttacgat atctttacac caatcgctgc aacagatctt
      721 ggttttgaac caggtatccc agttatcgaa gctgggccaa tcttattccg tataccagca
      781 atgagcgctc cagtatttga caatattaga ctccctgcga aacaaaatat ggtatagtag
      841 ttctatgaat gatgaagcaa gtaaacaact aactgatgca cgatttaagc gt
//
LOCUS       DAVKAU010000104          866 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVKAU010000104 DAVKAU010000000
VERSION     DAVKAU010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.105"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            4..744
                     /locus_tag="VWX48_002034"
     CDS             4..744
                     /locus_tag="VWX48_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9172577.1"
                     /translation="MENINIKIPEEKISVIIGSNGCGKSTLIKTLSRLIKPLEGEVLL
                     DNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGRFPYRKPFKSLGKDDLEII
                     NRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSILLLDEPTTYLDISYQIEL
                     LDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKLVAEGKPEDILNDKLVKDI
                     FNLEAKIIRDPISNSPLMIPIGKHHINS"
BASE COUNT          332 a          147 c          139 g          248 t
ORIGIN      
        1 atcttggaaa atataaatat aaaaatacct gaagaaaaaa tatcagttat tattgggtca
       61 aatggttgtg ggaaatcaac actcattaaa accttgtctc gacttataaa gccattagag
      121 ggagaagtat tgcttgataa taaatcaatt aattcttata aagaaaaaga tttagcaaaa
      181 cacatagcta tattacctca atctccaata atccctgaat caataacagt agctgatctt
      241 gtaagccgtg gtcgtttccc ctacagaaag ccttttaaga gtcttggaaa agatgacctt
      301 gaaataataa acagatcaat ggttaaggcc aatgttgaag atctagcaaa taacctagtt
      361 gaagaacttt ctgggggtca aaggcaaaga gtatggatag ctctagccct agcccaagat
      421 acaagtatcc tacttttaga tgagccaact acttacttgg atatctcata tcaaatagaa
      481 ctattagacc tcttgactga tctaaaccaa aaatataaga caaccatttg catgattttg
      541 cacgatataa atctaacagc aagatacgct gattacctat ttgcaattaa agaaggtaaa
      601 cttgttgcag agggaaagcc tgaagatata ctaaatgata aactagttaa agatatcttt
      661 aatcttgaag caaaaattat acgtgaccct atttccaatt cgcctctaat gattcctatt
      721 ggcaagcacc atattaactc ttaataattg aatattggaa ttcatttaaa agtcgcaaat
      781 tttgaactga ccctcaaaag ttaggccaaa aaactaacta aaggaggtca gttttttaat
      841 ggcaaataca gcacagaatt taagat
//
LOCUS       DAVKAU010000105          846 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVKAU010000105 DAVKAU010000000
VERSION     DAVKAU010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.106"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(296..607)
                     /locus_tag="VWX48_002035"
     CDS             complement(296..607)
                     /locus_tag="VWX48_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172578.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(622..>846)
                     /locus_tag="VWX48_002036"
     CDS             complement(622..>846)
                     /locus_tag="VWX48_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU9172579.1"
                     /translation="DQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIKVPQ
                     PVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          266 a          155 c          145 g          280 t
ORIGIN      
        1 ttccaacggc atgactgaga acatccacca cggttggcat cacgcatact ctagacggat
       61 tgttttgaca attctaatct tttagacttt gcataataac tgttaaacag ttgaaaatta
      121 acccagtttt aacaagtagt caaaatacca gataaaggaa aaaagtcttt aaaatcttaa
      181 aaacgcatag tatcaggtat tgaacaatct tgatattatg cgttttattg tgggaagatt
      241 tacttcattt tctcttggaa ttgagttttc tcctacttca aaactagatg atttgctatt
      301 taaaatagcg ttccttatga ttttggcaac ctggattaaa gcgagaaaaa caaaaggggc
      361 aacttaaact ttctttatat tgcttatatg ttagtagttt tagacaaaca ccacataaaa
      421 taggcttatc ctgtatcaaa gataagggat acggctcaaa agggtgattt tctaatgaat
      481 catgacaccg ataacaagca tagtactttt tacaatcata gcattgtaaa gcaataatat
      541 ccagcttgct atggtaatga atgcatcttg tttgcttatc cactaagaaa ccctgtgcct
      601 ctatcatttc cttttccttt cttaagctcg aactgtgacg ctggttccat cttccttata
      661 aagattgatg agtccttctt ttaatgcacg aaccatgtct cctgattgaa cgggttgtgg
      721 gactttaata gtcaatagtt ccattggatt tggagcgcgg tcgattttat tgcctttggc
      781 atcatgcaaa tcttcaatat aggtttcaaa atgacggaaa cctggaccat aaaactcaac
      841 ttggtc
//
LOCUS       DAVKAU010000106          821 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVKAU010000106 DAVKAU010000000
VERSION     DAVKAU010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.107"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..560)
                     /locus_tag="VWX48_002037"
     CDS             complement(<1..560)
                     /locus_tag="VWX48_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9172580.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLT"
     gene            complement(570..>821)
                     /locus_tag="VWX48_002038"
     CDS             complement(570..>821)
                     /locus_tag="VWX48_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEU9172581.1"
                     /translation="LDSVLSKVSSVLDGYVISCEVKMMKPQKEIYLSLVNKYQLDIKD
                     CIFLDDLEENVEAARTLGIKAFQIKERKEISNILKDLLN"
BASE COUNT          294 a          130 c           92 g          305 t
ORIGIN      
        1 gttaaatatt caaataaaga atgttctttt tcattagtaa gtgaaataaa atataaatta
       61 gatagctttt cagtccgaac caactcaagt acaatctcaa atattttatc actatcaaag
      121 gaagataaag ttttattaga ttgatatgta tctacttcaa aaatcggaat attatcttca
      181 atatcaacga atctttttgg agaaaaacct aagcaaacta taaattgagg attttcactt
      241 aaaattgcag atatcttatt tttaatctct gagaatttat gtaagtaaac atattctaca
      301 tctaaagata actgatcaat ttctgcaaaa tactcagcat actttttgcg tgcattatta
      361 aataacaaga aaaaacattt actagaagcg ccttttcgaa gaaactgagc ttgagaattc
      421 atattataac ccaatttttt cgcagtctct tctactaact ttattttagc tgctgagaca
      481 ttaccttttt tatttaaaac gtttgaaact gtcccatgtg agactccaga cactcttgca
      541 atatctttta ttgtaaccat aattaacctc tagtttaaga gatcttttag tatatttgag
      601 atctctttac gctctttaat ttgaaatgct ttaataccta gagttcttgc agcttctaca
      661 ttttcttcta aatcatctaa aaatatacaa tcttttatat ctaattgata tttattaact
      721 aatgacaagt aaatttcttt ttgtggtttc atcattttaa cttcacaaga aattacgtaa
      781 ccatctaaaa cagatgatac tttagataga acagaatcta a
//
LOCUS       DAVKAU010000107          796 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVKAU010000107 DAVKAU010000000
VERSION     DAVKAU010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.108"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            224..442
                     /locus_tag="VWX48_002039"
     CDS             224..442
                     /locus_tag="VWX48_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9172582.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
BASE COUNT          350 a           87 c          129 g          230 t
ORIGIN      
        1 cagacgatag aaattaaaaa ctctatcgtc ttttttatac tcaaaattag gaggtaaaaa
       61 tggtaaggat aagaggtccc acttaaaaca atttatggca aaataaggac ggaataacac
      121 aacaaattct ctaaaacaaa tcactaaatc aatgtaagat tgaatgaaat caatatttat
      181 gctataatta aataaattta atgaagaaaa aaagagggat attatggcac ttaactataa
      241 accattatgg atacagttag caaaaaaagg actaaagaaa acagatgtaa tagctatggc
      301 aggacttaca acaaatgtta tggcacaaat gggaaaggat aaaccaatta catttaagaa
      361 tttagaaaga atatgtaagg ctttatcttg cactcctaat gatattatta gttttgaaga
      421 taattttagt gacgaggaat agaaaatgac tttaaggaca gaagatcaag ttagggatta
      481 tgcaagagaa gtataggctt taatgaagtt gaagaaaaca tcaatcaagg tactggtcaa
      541 ataactactt ttaatcaatt aggcttcaag ggatattcag ataagccaga tggttggtat
      601 ttacctaaaa atatgaatga tgtagcaata atccttgaaa caaaatcaga agaaagagat
      661 attagcaaac aaatttttat tgatgagtta atgaaaaata tagacataat ttaactaaaa
      721 ataaaaacta gatccttttt tgaaaaaatt atattattaa atttgtaact gtatctattg
      781 acaatgataa ttatta
//
LOCUS       DAVKAU010000108          794 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVKAU010000108 DAVKAU010000000
VERSION     DAVKAU010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.109"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..>794
                     /locus_tag="VWX48_002040"
     CDS             <1..>794
                     /locus_tag="VWX48_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU9172583.1"
                     /translation="LQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKIL
                     HYHKQKFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNF
                     KPAGKSIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKT
                     AESVNQALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHN
                     RLIRRWLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          275 a          144 c          161 g          214 t
ORIGIN      
        1 tttacaacaa gtgagaaaag ggctatacaa aaaggtctat tctgccgatt acgcacaaac
       61 tgtttaccaa ttcaatcgaa aacggtcggt gaaaaagtta attttaacaa aggaaatcag
      121 agagaagatc ttacactatc ataagcaaaa attttcgcct gaaatgatgg ttaacaagaa
      181 gcaagtgaaa gttggtattt caaccatcta ctactggttt cataatggtc atttaggatt
      241 gacgaaggcc gacatgcttt atcccagaaa aaggaaaggt gtcaagaagc aagctagtcc
      301 gaactttaag ccggcaggta aatctatcga agaacgtcct gacgttatta atcttcgctt
      361 ggaaaatggt cattatgaaa ttgataccgt cctactgact aagataaaaa attattgcct
      421 gttagtctta accgaccggc ggagcagaca ccaaattata aggttaattc caaataaaac
      481 tgctgaatct gtcaatcagg cgcttacgtt actattaggg gagcatcgta ttctgtccat
      541 tactgcagat aatggttcgg agttcaaacg attgtctgag gtatttcctg aggaacatat
      601 ctactacgca catgcttact cttcatggga gagaggttca aatgaaaatc ataatcgatt
      661 aattcggaga tggttaccta aaggaaccaa gaaaacgact ccgaaagaag tagcttttat
      721 cgaaaattgg attaacaact accctaaaaa atgcttggac tacaagtcgc caagtgaatt
      781 tcttttgggt ggct
//
LOCUS       DAVKAU010000109          593 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVKAU010000109 DAVKAU010000000
VERSION     DAVKAU010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.110"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..>593
                     /locus_tag="VWX48_002041"
     CDS             <1..>593
                     /locus_tag="VWX48_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9172584.1"
                     /translation="EYQIKNLSYKFTDDECLSLKDISFKLGKIYGIIGSNGRGKSTLL
                     RCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFKDEVFNELRLGVKNFD
                     EEKAKIILKDLCLDEFIERHPMSLSGGQKQRLAIASVMCKNSPFVFFDEPSSGMDYSN
                     MIKISELINKYKTMDKIIFIVSHDIEFLNEVADEIFE"
BASE COUNT          230 a           68 c          111 g          184 t
ORIGIN      
        1 gagtatcaga taaaaaatct tagctacaaa tttactgatg atgagtgttt aagcttaaaa
       61 gatatttcgt tcaagcttgg gaaaatttat ggcataatag gatccaacgg acgaggaaaa
      121 tcaacgcttt taagatgttt aataggtctt gagaaaaaat caaaagaaga aatttatttt
      181 aagggagaga agctatctaa aaaagaaaga ctcaaaaact cttcacttgt tatgcaagat
      241 gtaaatcatc aattattcaa agatgaagta ttcaacgagc ttagattagg agtaaagaat
      301 tttgatgaag aaaaggcgaa aatcatttta aaagatttat gcctggacga atttattgaa
      361 aggcatccga tgagtttatc aggagggcaa aagcaaaggc ttgcaatagc atctgttatg
      421 tgcaagaatt ctccatttgt cttttttgac gaaccttcaa gtggtatgga ttattccaat
      481 atgataaaaa tatctgaact gattaataag tataaaacca tggataaaat aatttttatt
      541 gtttcccatg atatagaatt tttaaatgaa gtggcagatg aaatttttga att
//
LOCUS       DAVKAU010000110          511 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVKAU010000110 DAVKAU010000000
VERSION     DAVKAU010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.111"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..511
                     /locus_tag="VWX48_002042"
                     /pseudo
     CDS             1..511
                     /locus_tag="VWX48_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800706.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
BASE COUNT          211 a           54 c           86 g          160 t
ORIGIN      
        1 ataaaaaata agcaacaaaa actttttgag aagagtggga aaaaactcat aaaataaata
       61 caattatggt tcagggatta tgaaatcagc tagattgtaa tcatgtagtt agtagagatg
      121 atctaaattt agtatatgac tatttattcc agaaggaacg atgggagtcc tatgagataa
      181 cgctgattgg taatttatat catctttttg aaatagatta tatttacatg gtcggaaaag
      241 aaatactaga gcgtacacat tattacgaaa aaatcggcaa gaatagaaat ttagttgtgt
      301 cagcttgttt aaatttttgg ttctgttgcc ttgaaaattc acatctaata tatgcagact
      361 actttgaaat gaaattaaaa aaattattaa aggatgacac aaaagttttt gaaaaatcta
      421 cattcaaatt tgtagaagga tataaaatat acctgacaga atctaaagaa tctggaatta
      481 aacaaatgga caatgtcata aaatattttg a
//
LOCUS       DAVKAU010000111          429 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVKAU010000111 DAVKAU010000000
VERSION     DAVKAU010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.112"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..>429)
                     /locus_tag="VWX48_002043"
     CDS             complement(<1..>429)
                     /locus_tag="VWX48_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9172585.1"
                     /translation="IFRNNFMFIVSKWNLLYRKPYIKSISAAITGAILLISSFQMISQ
                     NILSQFQDDSDLELRVAFIVYVGAPILIVLANIISIAFLSSHQERIEIQQFEILGTSN
                     YQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYYSLEDIL"
BASE COUNT          171 a           66 c           53 g          139 t
ORIGIN      
        1 taaaatatcc tctaaagagt agtatattaa agccataatt ttaatgttaa gtaaaaatgc
       61 aattaatgaa gtaacaaatg tcaaaaatat agcctcacca actttaatct taaccatctg
      121 gtaattagaa gttcctaaaa tttcaaattg ctgaatctca atcctttctt gatgcgatga
      181 caaaaatgca attgaaataa tatttgcaag tactatcaaa attggtgctc ctacatagac
      241 aataaatgcc actcttagct ctaaatcact gtcatcttga aattgagata gtatattctg
      301 agaaatcatt tgaaaactag aaattagtaa tatagctcct gtaattgcag cactgataga
      361 ttttatataa ggcttacgat atagtaaatt ccacttcgaa acaatgaaca taaaattatt
      421 tctaaatat
//
LOCUS       DAVKAU010000112          410 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVKAU010000112 DAVKAU010000000
VERSION     DAVKAU010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.113"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..>410
                     /locus_tag="VWX48_002044"
     CDS             <1..>410
                     /locus_tag="VWX48_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9172586.1"
                     /translation="FGKERKSLQGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEG
                     RMKSIHYVSTVTNCYKAAVDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPS
                     ENEQLFGARRKIPEYKFVAEVVSYDDAAQTATIR"
BASE COUNT          124 a           74 c          101 g          111 t
ORIGIN      
        1 tttgggaaag aacgtaagag tttgcagggt gagattccag aagaattttc aatgtcagcc
       61 gttgacatgt ctatgattga ccacattcca gatatgattg aaaatggtgt ggacagtcta
      121 aaaatcgaag gacgtatgaa gtctattcac tacgtatcaa cagtaaccaa ctgctacaag
      181 gcggctgtgg atgcctatct tgaaagtcct gaaaagtttg aagctatcaa acaagacttg
      241 gtggacgaga tgtggaaggt tgcccaacgt gaactggcta caggatttta ctatggtaca
      301 ccatctgaaa atgagcagtt gtttggtgct cgccgtaaaa ttcctgagta caagtttgtc
      361 gctgaagtgg tttcttatga tgatgcggca caaacagcaa ccattcgtca
//
LOCUS       DAVKAU010000113          404 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVKAU010000113 DAVKAU010000000
VERSION     DAVKAU010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.denovo.114"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..404
                     /locus_tag="VWX48_002045"
                     /pseudo
     CDS             1..404
                     /locus_tag="VWX48_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          134 a           81 c           87 g          102 t
ORIGIN      
        1 gctaaagggg ttaacgtggg aatttcaacc atttactatt ggattcatca tggaaaattg
       61 gggtaaagca agcaggatct gctttaccct agaaaaggaa aagcgcttaa gaaacaggcc
      121 agcaccaact ttaaacctgc tggtcaatcc atcgaacagc ggcctgaagc tatcaatttt
      181 cgcttggaga atgggcatta tgagattgat acggttctac ttacgagagc gaaaaactac
      241 tgcttgcttg tcttgacgga tcgaaaaagt agacatcaga tcatccgatt gattccaaat
      301 aaaagtgctg aggtggtcaa tcaggctcta aaactcatct taaaacaaca caagattctt
      361 tccatcacgg cagataatgg aacggaattc aatcgcttgt ctaa
//
LOCUS       DAVKAU010000114         1661 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00060124
            SAMN33606257-rid17944653.guided.094, whole genome shotgun sequence.
ACCESSION   DAVKAU010000114 DAVKAU010000000
VERSION     DAVKAU010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606257
            Sequence Read Archive: SRR23727651
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722693.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722693.1
            Genome Coverage       :: 124x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 03:17:23
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,047
            CDSs (total)                      :: 1,997
            Genes (coding)                    :: 1,851
            CDSs (with protein)               :: 1,851
            Genes (RNA)                       :: 50
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 146
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 71 of 146
            Pseudo Genes (incomplete)         :: 67 of 146
            Pseudo Genes (internal stop)      :: 43 of 146
            Pseudo Genes (multiple problems)  :: 32 of 146
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606257-rid17944653.guided.094"
                     /strain="AUSMDU00060124"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2021"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            302..730
                     /locus_tag="VWX48_002046"
     CDS             302..730
                     /locus_tag="VWX48_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9172587.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            809..1396
                     /locus_tag="VWX48_002047"
     CDS             809..1396
                     /locus_tag="VWX48_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU9172588.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
BASE COUNT          613 a          216 c          341 g          491 t
ORIGIN      
        1 cacaaggaaa tcatcgccaa actggactac gacgcaccat gttgaggcag tatcactgct
       61 tgtacaagct gaggcatcag cgaagtagaa gtaaatgatc tcccatgcgg taggactcgt
      121 agaatgagga ggaaaaccga cgaaatgata aggtaagtcc gaaccgctga gtgcgtggct
      181 ctgctcttcc gatctgagac agtcgaaaag tagaagggga tggtattggt atcaatcaat
      241 gagtaacaaa gtatcagcat gattcgaaac atttacttgt aatttgcgga ggaacatcaa
      301 tatggatgga ataacaaaag attttataaa aacggctaaa ctaatgaaac aattatggcc
      361 ccaattgacc gataaagaag ctattgatga agtaaaaaaa tatacgaatg gcaaaaatac
      421 tgcaatcttt actgaagttg aaggtgacac aattgtaggt ctagcactat gttcactcag
      481 atttgattat gttgaaggtt gtaaatatag tcctgttgga ttcttagaag ggattattgt
      541 tgacgaggaa tatcgtttaa aggatattgc taaaaatctc tgtacaaaat gtgaggaatg
      601 ggcgaaaaat aaaggatgta aggaatttgc aagtgactgt actttaacga atacggattc
      661 tataagattt catctcaata ttggatttca ggaggcaaat agaattattc attttaagaa
      721 aaaattataa tttagaaacg tgaataaact tgtttaaact ttatgtatct ttagaaagtg
      781 tgttaacttg aaagaacaaa tttttttgat gggtgggaat cccccaatga agaaatatag
      841 tattgttgat aaaattgtat tatcaaccaa gattaaaaga attatcattt ttacagtttt
      901 tcgagaaaat tgggaaccgt acatgaaaaa gtacacggaa gtttttcaaa gtcaatttcc
      961 taatctaaac attgattact tgctcctgga cactgagcag attgatcttg atagctatct
     1021 agatgctgac ataattatca tcggtggtgg aaatacggaa aaatatattg ctacttatgt
     1081 taatcaggag ttcaaaagtt atatcgatca tatgcttaat aaagaggcaa aaattatagg
     1141 attttctgca ggagccctac tattaggaga aaaagtctat gtctcaccta atgataattc
     1201 agatcatcag ataaagataa aaaatggatt aggactcttt agtcagtttt taattagtgt
     1261 ccattatgat tcctggaatg ataaagcaaa taaggataga gctgaagaac tcgttaatgt
     1321 tcccataatt ccactaaatg atcattcttg tcttgtattg gataaacttg gaaacatcat
     1381 agagaaaatt gattaacttt cataatgtaa aaatggatct aggaaataaa agtgtagacg
     1441 aactggatag gttactagtg aaaactgcaa aaagtgttgt aaagtgaatc ggagtgtgct
     1501 tgatggattt tagtagtaag atagccataa ataaaggctg gtcagatgat aaaaaatatt
     1561 gtgtgacaga tcaaaatcag taaaaatatt tcttgcgtgt ttctgataag tcgaagttag
     1621 attataaaaa aatttgaatt tgatatgatg gagaaagtag c
//
